F ASCIOLA H EPATICA Amy Liberio Heather Peters. F ASCIOLA HEPATICA One of the worlds largest fluke...

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FASCIOLA HEPATICA Amy Liberio Heather Peters

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G EOGRAPHICAL D ISTRIBUTION Worldwide (excluding Antarctica) Where sheep or cattle are raised

Transcript of F ASCIOLA H EPATICA Amy Liberio Heather Peters. F ASCIOLA HEPATICA One of the worlds largest fluke...

Page 1: F ASCIOLA H EPATICA Amy Liberio Heather Peters. F ASCIOLA HEPATICA One of the worlds largest fluke Worm: 30 mm x 13 mm Distinguishable from other faciolidae.

FASCIOLA HEPATICAAmy LiberioHeather Peters

Page 2: F ASCIOLA H EPATICA Amy Liberio Heather Peters. F ASCIOLA HEPATICA One of the worlds largest fluke Worm: 30 mm x 13 mm Distinguishable from other faciolidae.

FASCIOLA HEPATICA One of the world’s largest fluke

Worm: 30 mm x 13 mm Distinguishable from other faciolidae by:

Oral cone “Shoulders”

Widening of body at base of oral cone Highly branched ceca

Page 3: F ASCIOLA H EPATICA Amy Liberio Heather Peters. F ASCIOLA HEPATICA One of the worlds largest fluke Worm: 30 mm x 13 mm Distinguishable from other faciolidae.

GEOGRAPHICAL DISTRIBUTION Worldwide (excluding Antarctica)

Where sheep or cattle are raised

Page 4: F ASCIOLA H EPATICA Amy Liberio Heather Peters. F ASCIOLA HEPATICA One of the worlds largest fluke Worm: 30 mm x 13 mm Distinguishable from other faciolidae.

HOSTS

Definitive host: sheep, cattle Accidental host: humans

Intermediate hosts: snails

Page 5: F ASCIOLA H EPATICA Amy Liberio Heather Peters. F ASCIOLA HEPATICA One of the worlds largest fluke Worm: 30 mm x 13 mm Distinguishable from other faciolidae.

MORPHOLOGICAL FORMS Fluke (worm) Eggs Micracidium Sporocyst Rediae Cercariae Metacercaria

Hermaphroditic

Page 6: F ASCIOLA H EPATICA Amy Liberio Heather Peters. F ASCIOLA HEPATICA One of the worlds largest fluke Worm: 30 mm x 13 mm Distinguishable from other faciolidae.

LIFE CYCLE

Page 7: F ASCIOLA H EPATICA Amy Liberio Heather Peters. F ASCIOLA HEPATICA One of the worlds largest fluke Worm: 30 mm x 13 mm Distinguishable from other faciolidae.

LIFE CYCLE Metacercariae ingested Young flukes released from cyst in digestive

tract Adult fluke moves to bile ducts Eggs are released and passed in feces Eggs develop in water and hatch miracidium Miracidium penetrates snail Mother sporocyst produce daughter rediae Daughter rediae produce cercariae Cercariae released in water Cercariae encyst and become metacercariae

Page 8: F ASCIOLA H EPATICA Amy Liberio Heather Peters. F ASCIOLA HEPATICA One of the worlds largest fluke Worm: 30 mm x 13 mm Distinguishable from other faciolidae.

INFECTION AND SIGNS Symptoms:

Gastrointestinal problems: Nausea Vomiting Abdominal pain/tenderness

Fever Rash Difficulty breathing Anemia Migrating juveniles can produce ulcers in eyes,

brain, skin and lungso Can eventually lead to Fascioliasis

Page 9: F ASCIOLA H EPATICA Amy Liberio Heather Peters. F ASCIOLA HEPATICA One of the worlds largest fluke Worm: 30 mm x 13 mm Distinguishable from other faciolidae.

DIAGNOSIS AND TREATMENTo Diagnosis:

o Eggs in stool sample (after a few months)o Enzyme-linked immunosorbent assay (ELISA)o Antibodies in blood sample

o Treatment:o Prescription drugs

o Rafoxanideo Trichlabendazole

o No vaccine

Page 10: F ASCIOLA H EPATICA Amy Liberio Heather Peters. F ASCIOLA HEPATICA One of the worlds largest fluke Worm: 30 mm x 13 mm Distinguishable from other faciolidae.

ECONOMIC IMPORTANCE Huge issue in cattle and sheep industries

Lowered productivity Lowered fertility Lowered quality of animal products

Page 11: F ASCIOLA H EPATICA Amy Liberio Heather Peters. F ASCIOLA HEPATICA One of the worlds largest fluke Worm: 30 mm x 13 mm Distinguishable from other faciolidae.

PREVENTION & CONTROL Control growth and sale of watercress and other

water plants Avoid potentially contaminated water and/or food Cook vegetables well that were possibly grown

with contaminated water

Page 12: F ASCIOLA H EPATICA Amy Liberio Heather Peters. F ASCIOLA HEPATICA One of the worlds largest fluke Worm: 30 mm x 13 mm Distinguishable from other faciolidae.

REVIEW What is a definitive host for F. Hepatica?

What are a few symptoms?

What morphological form is considered infective?

What is one way to prevent infection?