Extremes of Life Tutorial Questions Sept 2015 (2) (1)
2
Clinical Diagnostics and Therapeutics “Pharmacokinetics at the extremes of age” What is required of you? Each group will prepare a short presentation covering a different aspect of the above topic. Illustrate each presentation with no more five slides. Please bring these on a memory stick to the tutorial. Do not just put a lot of text on the slides – try to summarise your topic with a table or graph. Be critical. e.g. “It can happen but does it matter?” Give clinical examples. The quality of the tutorials will depend on your input - come prepared! Topics 1. Drug metabolism in the young and elderly. Is it different? How can we measure it? What are the reasons for it? What are its consequences? What can we do about it? 2. Must we adjust dose to take account of age? If so how? In what drug groups? What equations can we use to help make decisions? 3. Does body composition change with age? How might such changes affect drug pharmacokinetics? Please give examples! Clinical Diagnostics and Therapeutics JP Thompson Sept 2015
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Transcript of Extremes of Life Tutorial Questions Sept 2015 (2) (1)
Clinical Diagnostics and Therapeutics
“Pharmacokinetics at the extremes of age”
What is required of you?
Each group will prepare a short presentation covering a different aspect of the above topic. Illustrate each presentation with no more five slides. Please bring these on a memory stick to the tutorial. Do not just put a lot of text on the slides – try to summarise your topic with a table or graph. Be critical. e.g. “It can happen but does it matter?” Give clinical examples.
The quality of the tutorials will depend on your input - come prepared!
Topics
1. Drug metabolism in the young and elderly. Is it different? How can we measure it? What are the reasons for it? What are its consequences? What can we do about it?
2. Must we adjust dose to take account of age? If so how? In what drug groups? What equations can we use to help make decisions?
3. Does body composition change with age? How might such changes affect drug pharmacokinetics? Please give examples!
4. How does renal function vary with age and how might this affect pharmacokinetics? How do we measure it? To what groups of drugs is this relevant?
5. Why are the elderly more susceptible to adverse drug reactions? Please give examples to illustrate your discussion. What can we do about it?
Clinical Diagnostics and Therapeutics JP Thompson Sept 2015
Tutorial Topics Applied Clinical Sciences September 2015
Each group should prepare a short presentation on the topic allocated below.Group Topic Number Group Topic Number Group Topic Number Group Topic Number Group Topic Number
15/09/2015 Tuesday 09:00 - 12:00 D1 1 D2 2 E 3 E1 4 E2 515/09/2015 Tuesday 09:00 - 12:00 F 1 F1 2 F2 3 G 4 G1 515/09/2015 Tuesday 14:00 - 17:00 G2 1 H 2 H1 3 H2 4 I 515/09/2015 Tuesday 14:00 - 17:00 I1 1 J 2 J1 3 K 4 K1 517/09/2015 Thursday 09:00 - 12:00 L 1 L1 2 M 3 M1 4 N 517/09/2015 Thursday 09:00 - 12:00 N1 1 O 2 O1 3 P 4 P1 517/09/2015 Thursday 14:00 - 17:00 Q 1 Q1 2 R 3 R1 4 S 517/09/2015 Thursday 14:00 - 17:00 S1 1 T 2 T1 3 U 4 U1 518/09/2015 Friday 09:00 - 12:00 V 1 V1 2 W 3 W1 4 X 518/09/2015 Friday 09:00 - 12:00 X1 1 Y 2 Y1 3 Z 4 Z1 518/09/2015 Friday 14:00 - 17:00 A 1 A1 2 A2 3 B 4 B1 518/09/2015 Friday 14:00 - 17:00 B2 1 C 2 C1 3 C2 4 D 5
Clinical Diagnostics and Therapeutics JP Thompson Sept 2015
