ExSciTecH: Expanding Volunteer Computing to Explore Science, Technology, and Health.
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Transcript of ExSciTecH: Expanding Volunteer Computing to Explore Science, Technology, and Health.
ExSciTecH: Expanding Volunteer Computing to Explore Science, Technology, and Health
M. Matheny1, S. Schlachter1, L.M. Crouse2, E.T. Kimmel2, T. Estrada1, M. Schumann3, R. Armen3, G. ZoppeB2, and
M. Taufer1
1University of Delaware 2University of Millersville
3Thomas Jefferson University
Volunteer Computing • Volunteer Computing (VC) is a
form of distributed computing in which volunteers donate processing and storage resources to computing projects.
• Every job represents a portion of a larger problem whose computation is divided into smaller chunks and addressed in parallel.
• Applications suited for VC include searches in very large spaces, parameter tuning, and data analysis.
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Volunteers • Are not representative of the general population
• White males with a background in computers • Paradigm causes them to be passive • Lose interest in the project and uninstall the VC software within a few
months of participation
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Main Contribution • Problem: Volunteer Computing appeals to a very narrow demographic
– We want to utilize intuitive technologies and user interfaces to appeal to historic minorities in Science, Technology, Engineering and Mathematics (STEM)
• Problem: In VC participants are generally passive and not involved in the research process – We want to get volunteers to help solve important research problems
and make scientific discovery
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Outline • Background • Motivation and Plan • Implementation • Game Testing • Conclusion and Future Work
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Outline • Background • Motivation and Plan • Implementation • Testing • Conclusion and Future Work
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Docking@Home
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• Docking@Home is powered by Berkley Infrastructure for Network Computing (BOINC)
D@H Scientific Goals • Self-Docking
– Searching for protein inhibitors – Targeted diseases
• HIV • Breast cancer (trypsin)
• Cross-Docking – Identifying drug side effects – Look at proteins similar to the disease protein – Naïve approach: all to all
• All proteins • All ligands
– This is where we want to utilize volunteers to reduce search space
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Related Work • Fold.it
– Developed by the same team as Rosetta@Home – Aims to use volunteers to fold proteins through puzzles – Complements VC system, does not integrate with VC system
• Bossa – Developed by the BOINC team – Volunteers use cognition, knowledge, and intelligence to solve
problems • Luis von Ahn’s work
– Phetch – improving web accessibility – Games with a purpose (GWAP) – reCAPTCHA
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Outline • Background • Motivation and Plan • Implementation • Testing • Conclusion and Future Work
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Docking@Home: As it stands
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ExSciTecH: Learning Stage
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ExSciTecH: Engaging Stage
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ExSciTecH: Engaging Stage
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ExSciTecH: the full circle
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Outline • Background • Motivation and Plan • Implementation • Testing • Conclusion and Future Work
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BOINC Infrastructure
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BOINC"
Local File System"
Web Browser"
Upload"
Download"
BOINC DB"
Daemons"CGI
BOINC"BOINC"Client"
Web Interface!
Front-end!Client!
BOINC!
C L I E N T" S E R V E R"
Back-end!
BOINC + ExSciTecH
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Player" Teacher" BOINC"
Game DB"
Local File System"
Web Browser"
Upload"
Download"
BOINC DB"
Daemons"CGI
BOINC"
CGI Learn"
CGI Engage"
BOINC"Client"
Learn"Game"
Engage Game"
Web Interface!
Front-end!Client!
Player!Teacher!BOINC!
C L I E N T" S E R V E R"
ExSciTecH"Daemons"
Back-end!
VMD"
ExSciTecH Client
• Modularly designed – each game is a separate program and the client acts as a manager
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Learning Games • Teach volunteers about science without intimidating them • Several levels available:
– High school student – Under graduate student – Graduate student – Pharmaceutical student – Professional chemist
• As players progress through the levels the game becomes more challenging
• Familiarize volunteers with the science • Give D@H more exposure
– Students in classrooms
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Molecule Flashcards
• Players must identify or categorize a 3D molecule as it flies towards them • If the player incorrectly identifies the molecule they’re given access to
additional information about it
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Engaging Games • Volunteers have been trained by the learning stage • Building a job
– Short game – Game objects correlate to job input parameters
• Protein (disease) • Ligand (drug) • Ligand Confirmation • Ligand Rotation
• Submitting a job – Game submits these parameters to the server – Server builds a job based on these parameters
• Getting results – Good results More games! – Volunteering CPU time More games!
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Drag’n’Dock
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• Volunteers rotate a protein and select a ligand
• Then they fly a spaceship over the protein with the ligand in tow
• They attempt to dock the ligand in the protein with the space ship
• The game submits data to the server to build a D@H work unit
Drag’n’Dock • Volunteers rotate a
protein and select a ligand
• Then they fly a spaceship over the protein with the ligand in tow
• They attempt to dock the ligand in the protein with the space ship
• The game submits data to the server to build a D@H work unit
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Drag’n’Dock • Volunteers rotate a
protein and select a ligand
• Then they fly a spaceship over the protein with the ligand in tow
• They attempt to dock the ligand in the protein with the space ship
• The game submits data to the server to build a D@H work unit
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Outline • Background • Motivation and Plan • Implementation • Testing • Conclusion and Future Work
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Testing the Molecule Flashcard Game • What we want to learn:
– Do people learn more with the game than they do with a paper test? – Do they enjoy our game more than a paper test? – What improvements can we make to the game?
• How we tested: – We took a group of students and had half of them attempt to identify
molecules with our flashcard game and half of them attempt to identify molecules on a paper test
• What we measured: – Time to complete the game/test – Number of molecules correctly identified – Survey with level of enjoyment and comments
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Testing Setup • 24 computer science students
– 14 undergraduate students – 10 graduate students
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Vs.
• 10-minute introduction • Students split into two groups
– Paper test – Molecule flashcard game
Results and Discussion
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• Make more errors, but enjoy the game more • Tend to be faster – less reflection
Results and Discussion
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• Learning Curve • Confusing 3D representations
Outline • Background • Motivation and Plan • Implementation • Testing • Conclusion and Future Work
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Conclusions and Future Work • We can transform the way volunteers participate in VC projects
– More accessible – More exciting
• We show students had a higher level of enthusiasm when using ExSciTecH rather than traditional learning tools
• We identified improvements that could be made to the flashcard game: – Variable speed – Pause – Skip and come back
• We are moving forward with the ExSciTecH development by continuing development of engaging games
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Acknowledgments
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Thanks to: M. Matheny (UD) S. Schlachter (UD) L.M. Crouse (U. Millersville) E.T. Kimmel (U. Millersville) T. Estrada (UD) M. Schumann (TJU) R. Armen (TJU) G. ZoppeB (U. Millersville)
Sponsors: Contact: [email protected]
GCLab group
IIS #0968350/#0968368