Buffers used in dna overstretching and unzipping experiments
Experiments that led to the discovery of DNA
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Transcript of Experiments that led to the discovery of DNA
Experiments that led to the discovery of DNA
Spark notes Edition
Griffith
Experiment:1. S strain bacteria injected into mouse -> mouse died 2. R strain bacteria injected into mouse -> mouse lived3. Heated S strain injected into mouse -> mouse lived4. Heated S (dead) and alive R strain ->mouse died
Outcome: Cells contain a substance called transforming factor that can change the genome of a host.
AveryExperiment:1. S strain bacteria injected into mouse -> mouse died 2. R strain bacteria injected into mouse -> mouse lived3. Heated S strain injected into mouse -> mouse lived4. Heated S (dead) and alive R strain ->mouse died
Outcome: When the S strain was heated and killed its DNA was incorporated into the R strains DNA and changed the R strain into S strain.
*Still unknown whether DNA or protein was the “transforming factor”
Hershey-ChaseExperiment:
Outcome: DNA NOT proteins were the source of genetic material. DNA is the “transforming factor”