“Experience is simply the name we give our mistakes.” ~ Oscar Wilde

Friday, October 18, 2013

S.C. Standards for Today: B-2: The student will demonstrate an understanding of the structure and function of cells and their organelles.

Today’s Objectives:• Uncontrollable Cell Division• Cancer Mini- Research Activity

Reminder: Content Recovery must be completed by TODAY 10/18/13. Midterm, next Thursday 10/24/13.

Warm Up:

• What is the difference between primary and secondary succession?

• True or False: Commensalism is defined as both species benefitting from the relationship.

Uncontrollable Cell Division

Cell Cycle ControlCell cycle is driven by a chemical control system Triggers and coordinates the cell cycle

Regulated at certain checkpoints

Cell Cycle Control2 types of signals:

Internal signalsCell senses presence of enzymes that were produced inside

External SignalsCell senses chemicals that were produced outside in other cells

Cell Cycle ControlCells can respond to physical signals from their envt.

Examples: Too close= stop dividing Too much space= start division

G1

S

G2

M

CStart: Is the environment favorable?

G2/M:Is all the DNA replicated? Is the envt. favorable?

Metaphase/Anaphase: Are all of the chrom. attatched to the spindle?

What happens to the cell if it is not ready for the next step?

The cell can wait until the environment is favorable

It will hold the cell at the checkpoint until the problems are solved If all of the DNA is not copied correctly, cell cycle is held at the G2/M checkpoint until the error is corrected

ApoptosisProgrammed cell death

Suicide program is activated within an animal cell

Death is mediated by intracellular enzymes

Problems that cannot be fixed and the cell will self-destruct in for the benefit of the entire organism

Cells receive a change in signals

Mutagens Latin for origin of changePhysical or chemical agent that changes the genetic material

Increases the frequency of mutations

Carcinogens: Any agent, such as a chemical or

form of radiation that causes cancer

Cancer Cells ignore the normal signals that control cell division

Divide excessivelyNormally: immune system realizes that the cell is damage & destroys it

Cancer Abnormally: cell divides and each daughter cell is a cancer cell

Malignant tumor: mass of cells that invades and impairs the functions of one or more organs

Benign tumor: Mass of cells that remain at the original site

Mini-Cancer Research

You will work with one partner to research different types of cancer

You will select a cancer from the following list, based on how your stick is pulled from the bag

You will access the file from the website and submit via eBackpack

Name Cancer Type

Basal Cell Carcnoma

Bladder Cancer

Intraocular Melanoma

Fibrous Histiocytoma

Appendix Cancer

Mesothelioma

Kaposi Sarcoma

Nasal Cavity and Paranasal Sinus Cancer

Wilms Tumor

Pancreatic Cancer

Esophageal Cancer

Salivary Gland Cancer

Hodgkin Lymphoma

Soft Tissue Sarcoma

Oropharyngeal Cancer

Pituitary Tumor

Merkel Cell Carcinoma

Craniopharyngioma, Childhood

Stomach Cancer