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Transcript of Evaluation & Treatment of Urinary Incontinence Andy M. Norman, M.D. Assistant Clinical Professor,...
Evaluation & Treatment of Evaluation & Treatment of Urinary IncontinenceUrinary Incontinence
Andy M. Norman, M.D.Andy M. Norman, M.D.
Assistant Clinical Professor, Assistant Clinical Professor, Ob-GynOb-Gyn
Vanderbilt University Medical Vanderbilt University Medical CenterCenter
GoalsGoals
• Discuss Urinary Incontinence (UI)Discuss Urinary Incontinence (UI)
• Discuss Incidental Causes of UIDiscuss Incidental Causes of UI– DIAPERS MnemonicDIAPERS Mnemonic
• Discuss Preliminary DiagnosticsDiscuss Preliminary Diagnostics
• Discuss Treatment of Urgency UIDiscuss Treatment of Urgency UI
• Discuss Treatment of Stress UIDiscuss Treatment of Stress UI
• Discuss Overflow IncontinenceDiscuss Overflow Incontinence
• Review Some Cases of UI with Review Some Cases of UI with Emphasis on Medical ManagementEmphasis on Medical Management
AcknowledgementAcknowledgement
• Cases designed by:Cases designed by:
Dr. Patricia Goode, IM/Geriatrics, UABDr. Patricia Goode, IM/Geriatrics, UAB
• Special thanks to:Special thanks to:
Kathryn Burgio, PhD, UABKathryn Burgio, PhD, UAB– Author of “Staying Dry,” a self help book Author of “Staying Dry,” a self help book
for patients incontinence.for patients incontinence.
DisclaimerDisclaimerI am a Urogynaecologist. All of I am a Urogynaecologist. All of
my incontinence patients are my incontinence patients are female. This discussion is, female. This discussion is, therefore, mostly centered therefore, mostly centered around problems of females. around problems of females. Some of the observations and Some of the observations and treatments are also applicable to treatments are also applicable to male patients. male patients.
Prevalence of Urinary IncontinencePrevalence of Urinary Incontinence
• Age 15 to 64 1.5 - 5% men10-30% women
• Noninstitutionalized 15-35%>60 years old Twice as high in
women
• Homebound elderly 50%
• Nursing home residents 50% (two thirds if catheterized population included)
In 1995, more than $16.3 In 1995, more than $16.3 billion was spent on urinary billion was spent on urinary
incontinence care.incontinence care.More is spent on incontinence More is spent on incontinence
care than other chronic care than other chronic diseases such as breast diseases such as breast
cancer and osteoporosis.cancer and osteoporosis.
ICS DEFINITION OF ICS DEFINITION OF URINARY INCONTINENCEURINARY INCONTINENCE
Complaint of any Complaint of any involuntary leakage of urineinvoluntary leakage of urine
International Continence Society.Abrams P, et al. Neurourol Urodyn. 2002;21(2):167-178.
Urinary IncontinenceUrinary Incontinence
• Transient Causes of IncontinenceTransient Causes of Incontinence
• Urge IncontinenceUrge Incontinence
• Stress Urinary IncontinenceStress Urinary Incontinence
• Mixed Incontinence Mixed Incontinence – Both Urgency & Stress InducedBoth Urgency & Stress Induced
• Overflow IncontinenceOverflow Incontinence
URINARY URINARY INCONTINENCE INCONTINENCE
URINARY URINARY INCONTINENCE INCONTINENCE
• 3884 community-dwelling older adult 3884 community-dwelling older adult volunteers for a health promotion studyvolunteers for a health promotion study
• Ages 65 – 79Ages 65 – 79
• 1104 (28.4%) had self-reported incontinence1104 (28.4%) had self-reported incontinence
Burgio, et al: JAGS 42: 208, 1994Burgio, et al: JAGS 42: 208, 1994
• 3884 community-dwelling older adult 3884 community-dwelling older adult volunteers for a health promotion studyvolunteers for a health promotion study
• Ages 65 – 79Ages 65 – 79
• 1104 (28.4%) had self-reported incontinence1104 (28.4%) had self-reported incontinence
Burgio, et al: JAGS 42: 208, 1994Burgio, et al: JAGS 42: 208, 1994
Treatment Seeking (1)Treatment Seeking (1)
URINARY URINARY INCONTINENCE INCONTINENCE
URINARY URINARY INCONTINENCE INCONTINENCE
Treatment Seeking (2)
Burgio et al: JAGS 42: 208, 1994
Volume
31
4757
0
20
40
60
80
100
Drop or Two ChangeUndergarments
Wet OuterClothing
% r
ep
ort
ing
to M
.D.
URINARY INCONTINENCEURINARY INCONTINENCE
• Personal problem (not medical)Personal problem (not medical)• EmbarrassedEmbarrassed• Normal after childbearingNormal after childbearing• Normal aging changeNormal aging change• Fear of nursing home placementFear of nursing home placement• Afraid treatment requires Afraid treatment requires
surgerysurgery
Failure to Report UI to Health Care ProviderFailure to Report UI to Health Care Provider
INCONTINENCEINCONTINENCE
YOU GOTTA ASK!!YOU GOTTA ASK!!
Diagnosis of UIDiagnosis of UI
• HistoryHistory
• Physical ExamPhysical Exam1.1. Pelvic Organ Prolapse AssessmentPelvic Organ Prolapse Assessment
2.2. In & Out Cath for Residual Urine VolumeIn & Out Cath for Residual Urine Volume
3.3. U/A U/A +/-+/- Urine C & S Urine C & S
4.4. Qtip Test for Bladder Neck HypermobilityQtip Test for Bladder Neck Hypermobility
BLADDER DIARYBLADDER DIARY• Fluid intakeFluid intake
– Time, type, amountTime, type, amount
• Urine outputUrine output– Time, amountTime, amount
• Urine leakageUrine leakage– Time, amountTime, amount– Precipitating events (cough, sneeze, exercise, Precipitating events (cough, sneeze, exercise,
etc.)etc.)– Associated symptoms (urgency, pain, etc.)Associated symptoms (urgency, pain, etc.)
• Pad usagePad usage– Number, typeNumber, type
Transient Causes of UITransient Causes of UI
• DDrugs & rugs & DDietiet• IInfectionnfection• AAtrophic Urethritistrophic Urethritis• PPsychological - Depression, Deliriumsychological - Depression, Delirium• EEndocrine - Diabetes, Hypercalcemiandocrine - Diabetes, Hypercalcemia• RRestricted Mobilityestricted Mobility• SStool Impactiontool Impaction
Transient Causes of UITransient Causes of UI• DRUGS DRUGS
– ACE Inhibitors -- coughACE Inhibitors -- cough– Alpha Blockers – relax internal sphincterAlpha Blockers – relax internal sphincter– Anticholinergics/Antimuscularinics – decrease Anticholinergics/Antimuscularinics – decrease
effective bladder emptyingeffective bladder emptying– Diuretics -- timingDiuretics -- timing– Neuroleptics – pseudoparkinsonismNeuroleptics – pseudoparkinsonism– Sedatives – especially in the dementedSedatives – especially in the demented
• DIETDIET– Caffeine – provokes detrusor instabilityCaffeine – provokes detrusor instability– Artificial Sweeteners-bladder irritantsArtificial Sweeteners-bladder irritants
Urgency IncontinenceUrgency Incontinence(Overactive Bladder)(Overactive Bladder)
Therapeutic OptionsTherapeutic Options
Behavioral Treatment: Behavioral Treatment: Multi-component ProgramsMulti-component Programs
• Pelvic floor muscle trainingPelvic floor muscle training
• Home practice and exerciseHome practice and exercise
• Self-MonitoringSelf-Monitoring
• Voiding schedules—timed and Voiding schedules—timed and prompted voidingprompted voiding
• ““Urge” strategies—FREEZE & Urge” strategies—FREEZE & SQUEEZESQUEEZE
BiofeedbackBiofeedback
• Teaching methodTeaching method
• Facilitates learned control of Facilitates learned control of physiological responsesphysiological responses
• Patients learn by feedback of Patients learn by feedback of their attempts to control bladder their attempts to control bladder and sphincter responses.and sphincter responses.
Detrusor ContractionDetrusor Contraction
10 mmHg10 mmHg
U
Urge WaveUrge Wave
When the Urge StrikesWhen the Urge Strikes“Freeze & Squeeze”“Freeze & Squeeze”
• Stop and stay stillStop and stay still
• Squeeze pelvic floor musclesSqueeze pelvic floor muscles
• Relax rest of bodyRelax rest of body
• Concentrate on suppressing Concentrate on suppressing urgeurge
• Wait until the urge subsidesWait until the urge subsides
• Walk to bathroom at normal Walk to bathroom at normal pacepace
When to VoidWhen to Void
WorstWorstTimeTime
WorstWorstTimeTime
BestBestTimeTime
CalmCalmPeriodPeriod
RCT Comparing RCT Comparing Behavior and Drug TherapyBehavior and Drug Therapy
• 197 older, community-197 older, community-dwelling women with Urge dwelling women with Urge IncontinenceIncontinence
• Randomized to:Randomized to:– Behavioral training Behavioral training (biofeedback)(biofeedback)
– Drug therapy (oxybutynin)Drug therapy (oxybutynin)– Placebo controlPlacebo control
Burgio et alBurgio et al, JAMA, , JAMA, 19981998
Biofeedback-Assisted Biofeedback-Assisted Behavioral TreatmentBehavioral Treatment
• Visit #1:Visit #1: Anorectal BF to teach PFM Anorectal BF to teach PFM control. Home exercise instructions.control. Home exercise instructions.
• Visit #2:Visit #2: “Urge strategies” and “stress “Urge strategies” and “stress strategies”strategies”
• Visit #3:Visit #3: If not If not >>50% improved, 50% improved, bladder/sphincter biofeedbackbladder/sphincter biofeedback
• Visit #4:Visit #4: Individual adjustments and Individual adjustments and reinforcementreinforcement
Reduction of IncontinenceReduction of Incontinencein the Randomized Clinical in the Randomized Clinical
TrialTrial
81%
39%
68%
0
20
40
60
80
100
Behavioral Drug Control
% R
edu
ctio
n
Patient Satisfaction with Patient Satisfaction with Treatment Treatment
for Urge Urinary Incontinencefor Urge Urinary Incontinence
78%
22%
0%
49%
40%
11%
28%34%
38%
0%10%20%30%40%50%60%70%80%90%
Completelysatisfied
Somewhatsatisfied
Not satisfied
BehaviorDrugPlacebo
Behavioral Training Behavioral Training
• Tested the same behavioral Tested the same behavioral program with all components program with all components minusminus biofeedbackbiofeedback
vs.vs.• Verbal feedback based on Vaginal Verbal feedback based on Vaginal
PalpationPalpationvs.vs.
• Same program, but Booklet form Same program, but Booklet form (Minimal Treatment Control).(Minimal Treatment Control).
Is Biofeedback a necessary component?
Is Biofeedback a necessary component?
Burgio, Goode, et.al., Burgio, Goode, et.al., JAMAJAMA, 2002, 2002Burgio, Goode, et.al., Burgio, Goode, et.al., JAMAJAMA, 2002, 2002
Reduction of IncontinenceReduction of Incontinencein a Randomized Clinical Trialin a Randomized Clinical Trial
74% 64%69%
0
20
40
60
80
100
Biofeedback ManualTraining
Booklet
% R
edu
ctio
n
Burgio, Goode, et.al., JAMA, 2002Burgio, Goode, et.al., JAMA, 2002
Stress urinary incontinence is the Stress urinary incontinence is the most common type of most common type of incontinence in womenincontinence in women
Burgio, Matthews and Engel, Burgio, Matthews and Engel, 19911991
Stress incontinence = Urethral incompetence
Bladder Neck HypermobilityIntrinsic Sphincter DeficiencyPelvic Organ Prolapse
Treatments for SUI
• Pelvic Floor Physical Therapy
• Topical Estrogen Therapy
• Urethral Plugs
• Incontinence Pessaries
• Surgical Therapy
Women’s lifetime risk of surgery for SUI or POP is 11%
Olsen, Smith and Bergstrom, 1997
The Sling is the Thing!
TVT – Transvaginal Tape
• Relatively new procedure
• Large cohort analysis shows cure rate 80%, improvement 94%
Kuuva, 2000
• Numerous surgical techniques to treat stress incontinence
• Important to know both objective and subjective cure rates as well as side effects of surgical procedures
• Thoughtful evaluation of patients with individualization of therapy is advisable
CONCLUSIONS regards Surgical Care of SUI
Overflow Incontinence
• Common Causes1. Obstuctive Uropathy such as BPH in men
and Pelvic Organ Prolapse in women.
2. Neurogenic Bladder
• Treatments1. Relief of the Obstruction
2. Clean Intermittent Self Catheterization
3. Indwelling Catheters
4. Diversion Procedures
SUMMARY
• Incontinence is very common, so question ALL patients
• Reversible causes of UI– D – I – A – P – E – R – S
• Behavioral Therapy– Effective– No side effects
Transient Causes of UI
• Drugs & Diet• Infection• Atrophic Urethritis• Psychological - Depression, Delirium• Endocrine - Diabetes, Hypercalcemia• Restricted Mobility• Stool Impaction
Try with Some Case StudiesTry with Some Case Studies
PATIENT CASE 1 PATIENT CASE 1 PATIENT CASE 1 PATIENT CASE 1
• 48 year old woman48 year old woman– Complains that she just can’t get to Complains that she just can’t get to
the bathroom fast enough for the the bathroom fast enough for the past 3 monthspast 3 months
– 1-2 urge accidents per day (no 1-2 urge accidents per day (no stress)stress)
– Nocturia x 2, often with an accidentNocturia x 2, often with an accident– Wears a pad all the timeWears a pad all the time– Wants a bladder tackWants a bladder tack
• 48 year old woman48 year old woman– Complains that she just can’t get to Complains that she just can’t get to
the bathroom fast enough for the the bathroom fast enough for the past 3 monthspast 3 months
– 1-2 urge accidents per day (no 1-2 urge accidents per day (no stress)stress)
– Nocturia x 2, often with an accidentNocturia x 2, often with an accident– Wears a pad all the timeWears a pad all the time– Wants a bladder tackWants a bladder tack
History
PATIENT CASE 1 PATIENT CASE 1 PATIENT CASE 1 PATIENT CASE 1
• Last menstrual period 6 Last menstrual period 6 months agomonths ago– Having hot flashesHaving hot flashes– Afraid to take hormone Afraid to take hormone
replacement therapyreplacement therapy
• Trying to lose weight; drinks Trying to lose weight; drinks 6-8 diet Cokes per day6-8 diet Cokes per day
• Last menstrual period 6 Last menstrual period 6 months agomonths ago– Having hot flashesHaving hot flashes– Afraid to take hormone Afraid to take hormone
replacement therapyreplacement therapy
• Trying to lose weight; drinks Trying to lose weight; drinks 6-8 diet Cokes per day6-8 diet Cokes per day
History
PATIENT CASE 1 PATIENT CASE 1 PATIENT CASE 1 PATIENT CASE 1 • EXAMEXAM
– Vaginal mucosa mildly atrophicVaginal mucosa mildly atrophic– Otherwise exam normalOtherwise exam normal
• URINALYSISURINALYSIS– NormalNormal
• PVRPVR– 40 cc40 cc
• EXAMEXAM– Vaginal mucosa mildly atrophicVaginal mucosa mildly atrophic– Otherwise exam normalOtherwise exam normal
• URINALYSISURINALYSIS– NormalNormal
• PVRPVR– 40 cc40 cc
PATIENT CASE 1PATIENT CASE 1
• DDrugs & Dietrugs & Diet1.1. CaffieneCaffiene2.2. Taper off caffeine ½ per weekTaper off caffeine ½ per week3.3. Begin ExercisingBegin Exercising
• IInfectionnfection• AAtrophic Urethritistrophic Urethritis
1.1. YesYes2.2. Consider HRTConsider HRT3.3. Vaginal estrogen cream – ½ gram 3 Vaginal estrogen cream – ½ gram 3
times/week to vaginal entrancetimes/week to vaginal entrance
PATIENT CASE 1PATIENT CASE 1
•PPsychological - nosychological - no•EEndocrine - nondocrine - no•RRestricted Mobility – noestricted Mobility – no•SStool Impaction – notool Impaction – no
PATIENT CASE 1 PATIENT CASE 1 PATIENT CASE 1 PATIENT CASE 1
• Taper off CaffeineTaper off Caffeine• Vaginal EstrogenVaginal Estrogen
• Drugs?Drugs?– Hold off for nowHold off for now
• Behavioral TrainingBehavioral Training
• Taper off CaffeineTaper off Caffeine• Vaginal EstrogenVaginal Estrogen
• Drugs?Drugs?– Hold off for nowHold off for now
• Behavioral TrainingBehavioral Training
TREATMENT
PATIENT CASE 1 PATIENT CASE 1 PATIENT CASE 1 PATIENT CASE 1
• Teach Kegel exercises during her Teach Kegel exercises during her examexam
• Home ExercisesHome Exercises– 10 paired contractions and 10 paired contractions and
relaxationsrelaxations– 3 seconds each – build up to 10 3 seconds each – build up to 10
secondsseconds– TID (standing, sitting, lying)TID (standing, sitting, lying)
• Urge StrategyUrge Strategy– Freeze/Squeeze to suppress urgencyFreeze/Squeeze to suppress urgency
• RTC 1 monthRTC 1 month
• Teach Kegel exercises during her Teach Kegel exercises during her examexam
• Home ExercisesHome Exercises– 10 paired contractions and 10 paired contractions and
relaxationsrelaxations– 3 seconds each – build up to 10 3 seconds each – build up to 10
secondsseconds– TID (standing, sitting, lying)TID (standing, sitting, lying)
• Urge StrategyUrge Strategy– Freeze/Squeeze to suppress urgencyFreeze/Squeeze to suppress urgency
• RTC 1 monthRTC 1 month
Behavioral Treatment
PATIENT CASE 1 PATIENT CASE 1 PATIENT CASE 1 PATIENT CASE 1
• Doing much betterDoing much better• Down to 1-2 accidents per Down to 1-2 accidents per
weekweek• Nocturia resolvedNocturia resolved• Continue Behavioral TherapyContinue Behavioral Therapy
– Will continue to improve for 6 Will continue to improve for 6 monthsmonths
• RTC 3 monthsRTC 3 months
• Doing much betterDoing much better• Down to 1-2 accidents per Down to 1-2 accidents per
weekweek• Nocturia resolvedNocturia resolved• Continue Behavioral TherapyContinue Behavioral Therapy
– Will continue to improve for 6 Will continue to improve for 6 monthsmonths
• RTC 3 monthsRTC 3 months
Return Visit
PATIENT CASE 2 PATIENT CASE 2 PATIENT CASE 2 PATIENT CASE 2
• 26 year old woman, P 100126 year old woman, P 1001• Leaks when she sneezes or Leaks when she sneezes or
coughscoughs• Has to wear a pad all the timeHas to wear a pad all the time• Planning to have 2 more childrenPlanning to have 2 more children• Smokes 1 PPDSmokes 1 PPD• Has diabetes – last Hgb A1C = Has diabetes – last Hgb A1C =
8.08.0
• 26 year old woman, P 100126 year old woman, P 1001• Leaks when she sneezes or Leaks when she sneezes or
coughscoughs• Has to wear a pad all the timeHas to wear a pad all the time• Planning to have 2 more childrenPlanning to have 2 more children• Smokes 1 PPDSmokes 1 PPD• Has diabetes – last Hgb A1C = Has diabetes – last Hgb A1C =
8.08.0
History
PATIENT CASE 2 PATIENT CASE 2 PATIENT CASE 2 PATIENT CASE 2
• Small cystoceleSmall cystocele• Q tip test – 60Q tip test – 60o o rotation with coughrotation with cough• No leakage with coughNo leakage with cough• Otherwise normalOtherwise normal
• Normal UrinalysisNormal Urinalysis• PVR = 25PVR = 25
• Small cystoceleSmall cystocele• Q tip test – 60Q tip test – 60o o rotation with coughrotation with cough• No leakage with coughNo leakage with cough• Otherwise normalOtherwise normal
• Normal UrinalysisNormal Urinalysis• PVR = 25PVR = 25
ExamExam
TestsTests
PATIENT CASE 2 PATIENT CASE 2 PATIENT CASE 2 PATIENT CASE 2
• Surgery & MedicationSurgery & Medication– Still 2 more pregnancies Still 2 more pregnancies
plannedplanned
• PessaryPessary– She is not enthusedShe is not enthused
• Behavioral TrainingBehavioral Training
• Surgery & MedicationSurgery & Medication– Still 2 more pregnancies Still 2 more pregnancies
plannedplanned
• PessaryPessary– She is not enthusedShe is not enthused
• Behavioral TrainingBehavioral Training
Treatment Treatment OptionsOptions
PATIENT CASE 2 PATIENT CASE 2 PATIENT CASE 2 PATIENT CASE 2
• Teach Kegel exercises during her examTeach Kegel exercises during her exam• Get/Read “7 Steps to Normal Bladder Get/Read “7 Steps to Normal Bladder
Control”Control”• Home ExercisesHome Exercises
– 10 paired contractions and relaxations10 paired contractions and relaxations– 3 seconds each – build up to 10 seconds3 seconds each – build up to 10 seconds– TID in 3 positions (standing, sitting, TID in 3 positions (standing, sitting,
lying)lying)• Stress StrategyStress Strategy
– Squeeze before you sneeze or coughSqueeze before you sneeze or cough• RTC 1-3 monthsRTC 1-3 months
• Teach Kegel exercises during her examTeach Kegel exercises during her exam• Get/Read “7 Steps to Normal Bladder Get/Read “7 Steps to Normal Bladder
Control”Control”• Home ExercisesHome Exercises
– 10 paired contractions and relaxations10 paired contractions and relaxations– 3 seconds each – build up to 10 seconds3 seconds each – build up to 10 seconds– TID in 3 positions (standing, sitting, TID in 3 positions (standing, sitting,
lying)lying)• Stress StrategyStress Strategy
– Squeeze before you sneeze or coughSqueeze before you sneeze or cough• RTC 1-3 monthsRTC 1-3 months
Behavioral Behavioral TreatmentTreatment
PATIENT CASE 2 PATIENT CASE 2 PATIENT CASE 2 PATIENT CASE 2
• Diabetes – suboptimal controlDiabetes – suboptimal control• Tobacco useTobacco use
• Quit SmokingQuit Smoking• Diabetes EducationDiabetes Education
• Diabetes – suboptimal controlDiabetes – suboptimal control• Tobacco useTobacco use
• Quit SmokingQuit Smoking• Diabetes EducationDiabetes Education
Other Other DiagnosesDiagnoses
Other TreatmentsOther TreatmentsOther TreatmentsOther Treatments
PATIENT CASE 2 PATIENT CASE 2 PATIENT CASE 2 PATIENT CASE 2
• She is much improved, She is much improved, both in volume and both in volume and frequency of accidentsfrequency of accidents
• Only wearing a minipad Only wearing a minipad when she goes outwhen she goes out
• Completely satisfied with Completely satisfied with her treatmenther treatment
• She is much improved, She is much improved, both in volume and both in volume and frequency of accidentsfrequency of accidents
• Only wearing a minipad Only wearing a minipad when she goes outwhen she goes out
• Completely satisfied with Completely satisfied with her treatmenther treatment
Return VisitReturn Visit
PATIENT CASE 3 PATIENT CASE 3 PATIENT CASE 3 PATIENT CASE 3
• 65 year old woman65 year old woman• Can’t reach the bathroom in Can’t reach the bathroom in
timetime• 5-6 accidents / day5-6 accidents / day• Urinary frequency and urgency Urinary frequency and urgency
interfering with her golf gameinterfering with her golf game• Wants something done Wants something done
yesterday!yesterday!
• 65 year old woman65 year old woman• Can’t reach the bathroom in Can’t reach the bathroom in
timetime• 5-6 accidents / day5-6 accidents / day• Urinary frequency and urgency Urinary frequency and urgency
interfering with her golf gameinterfering with her golf game• Wants something done Wants something done
yesterday!yesterday!
HistoryHistory
PATIENT CASE 3 PATIENT CASE 3 PATIENT CASE 3 PATIENT CASE 3
• MedsMeds– HCTZ 50 mg/dayHCTZ 50 mg/day– AspirinAspirin
• NKDANKDA• S/P TAHS/P TAH
• MedsMeds– HCTZ 50 mg/dayHCTZ 50 mg/day– AspirinAspirin
• NKDANKDA• S/P TAHS/P TAH
HistoryHistory
PATIENT CASE 3 PATIENT CASE 3 PATIENT CASE 3 PATIENT CASE 3
• Atrophic mucosaAtrophic mucosa• Small CystoceleSmall Cystocele• No leakage with coughNo leakage with cough
• Urinalysis - normalUrinalysis - normal• PVR = 30 ccPVR = 30 cc
• Atrophic mucosaAtrophic mucosa• Small CystoceleSmall Cystocele• No leakage with coughNo leakage with cough
• Urinalysis - normalUrinalysis - normal• PVR = 30 ccPVR = 30 cc
ExamExam
TestingTesting
PATIENT CASE 3 PATIENT CASE 3 PATIENT CASE 3 PATIENT CASE 3
• Dx – Urge UI, Atrophic VaginitisDx – Urge UI, Atrophic Vaginitis• D/C HCTZ, start beta blocker or D/C HCTZ, start beta blocker or
ACE inhibitor for BP controlACE inhibitor for BP control• Estrogen Cream ½ gram 3x / wk Estrogen Cream ½ gram 3x / wk
(apply into introitus with finger (apply into introitus with finger amount like kidney bean size)amount like kidney bean size)
• Ditropan XL 5 mg dailyDitropan XL 5 mg daily• RTC 1 monthRTC 1 month
• Dx – Urge UI, Atrophic VaginitisDx – Urge UI, Atrophic Vaginitis• D/C HCTZ, start beta blocker or D/C HCTZ, start beta blocker or
ACE inhibitor for BP controlACE inhibitor for BP control• Estrogen Cream ½ gram 3x / wk Estrogen Cream ½ gram 3x / wk
(apply into introitus with finger (apply into introitus with finger amount like kidney bean size)amount like kidney bean size)
• Ditropan XL 5 mg dailyDitropan XL 5 mg daily• RTC 1 monthRTC 1 month
TreatmentTreatment
PATIENT CASE 3 PATIENT CASE 3 PATIENT CASE 3 PATIENT CASE 3
• Doing betterDoing better• Only 1-2 accidents per day versus Only 1-2 accidents per day versus
5-6, but often large volume, still 5-6, but often large volume, still afraid to play golf.afraid to play golf.
• Taking Ditropan XL 5 mg, but Taking Ditropan XL 5 mg, but mouth is quite drymouth is quite dry
• Teach pelvic muscle exercises and Teach pelvic muscle exercises and urge strategiesurge strategies
• RTC 1 monthRTC 1 month
• Doing betterDoing better• Only 1-2 accidents per day versus Only 1-2 accidents per day versus
5-6, but often large volume, still 5-6, but often large volume, still afraid to play golf.afraid to play golf.
• Taking Ditropan XL 5 mg, but Taking Ditropan XL 5 mg, but mouth is quite drymouth is quite dry
• Teach pelvic muscle exercises and Teach pelvic muscle exercises and urge strategiesurge strategies
• RTC 1 monthRTC 1 month
Visit 2Visit 2
PATIENT CASE 3 PATIENT CASE 3 PATIENT CASE 3 PATIENT CASE 3
• Doing much betterDoing much better• Able to play golfAble to play golf• 1 accident in last 2 weeks1 accident in last 2 weeks• Continue Behavioral Continue Behavioral
Therapy, Meds, Estrogen Therapy, Meds, Estrogen creamcream
• RTC 3 monthsRTC 3 months
• Doing much betterDoing much better• Able to play golfAble to play golf• 1 accident in last 2 weeks1 accident in last 2 weeks• Continue Behavioral Continue Behavioral
Therapy, Meds, Estrogen Therapy, Meds, Estrogen creamcream
• RTC 3 monthsRTC 3 months
Visit 3Visit 3
PATIENT CASE 3 PATIENT CASE 3 PATIENT CASE 3 PATIENT CASE 3
• Continues to do wellContinues to do well• Golf game improvingGolf game improving• Rare accident in last 2 Rare accident in last 2
monthsmonths• D/C Ditropan XL?D/C Ditropan XL?
• Continues to do wellContinues to do well• Golf game improvingGolf game improving• Rare accident in last 2 Rare accident in last 2
monthsmonths• D/C Ditropan XL?D/C Ditropan XL?
Visit 3Visit 3
PATIENT CASE 4 PATIENT CASE 4 PATIENT CASE 4 PATIENT CASE 4
• 80 year old woman, 80 year old woman, referred by her golf referred by her golf partnerpartner
• Can’t reach the bathroom Can’t reach the bathroom in timein time
• 5-6 urge accidents / day5-6 urge accidents / day• Gave up golfGave up golf
• 80 year old woman, 80 year old woman, referred by her golf referred by her golf partnerpartner
• Can’t reach the bathroom Can’t reach the bathroom in timein time
• 5-6 urge accidents / day5-6 urge accidents / day• Gave up golfGave up golf
HistoryHistory
PATIENT CASE 4 PATIENT CASE 4 PATIENT CASE 4 PATIENT CASE 4
• ExamExam– Mildly atrophic vaginal Mildly atrophic vaginal
mucosamucosa
• UrinalysisUrinalysis– NormalNormal
• PVR = 80PVR = 80
• ExamExam– Mildly atrophic vaginal Mildly atrophic vaginal
mucosamucosa
• UrinalysisUrinalysis– NormalNormal
• PVR = 80PVR = 80
PATIENT CASE 4 PATIENT CASE 4 PATIENT CASE 4 PATIENT CASE 4
• Declines Estrogen Vaginal creamDeclines Estrogen Vaginal cream
• You prescribe Detrol LA 4 mg dailyYou prescribe Detrol LA 4 mg daily
• She calls and tells you her She calls and tells you her frequency and urgency are worsefrequency and urgency are worse
• What is going on?What is going on?
• Declines Estrogen Vaginal creamDeclines Estrogen Vaginal cream
• You prescribe Detrol LA 4 mg dailyYou prescribe Detrol LA 4 mg daily
• She calls and tells you her She calls and tells you her frequency and urgency are worsefrequency and urgency are worse
• What is going on?What is going on?
TreatmentTreatment
PATIENT CASE 4 PATIENT CASE 4 PATIENT CASE 4 PATIENT CASE 4
• Urinalysis normalUrinalysis normal• PVR = 200 ccPVR = 200 cc• What do you do?What do you do?• D/C DetrolD/C Detrol• Teach her pelvic muscle Teach her pelvic muscle
exercise and the urge exercise and the urge strategystrategy
• RTC 1 monthRTC 1 month
• Urinalysis normalUrinalysis normal• PVR = 200 ccPVR = 200 cc• What do you do?What do you do?• D/C DetrolD/C Detrol• Teach her pelvic muscle Teach her pelvic muscle
exercise and the urge exercise and the urge strategystrategy
• RTC 1 monthRTC 1 month
Return VisitReturn Visit
PATIENT CASE 4PATIENT CASE 4
• Urgency is much betterUrgency is much better• Urge strategy really worksUrge strategy really works• Only 1-2 very small accidents per Only 1-2 very small accidents per
week; also she’s gained control of week; also she’s gained control of her flatusher flatus
• She thinks she will try golf againShe thinks she will try golf again• PVR = 50 ccPVR = 50 cc• Continue Pelvic Muscle Exercises Continue Pelvic Muscle Exercises
and Urge Strategyand Urge Strategy• RTC 3 monthsRTC 3 months
Return VisitReturn VisitReturn VisitReturn Visit
PATIENT CASE 5PATIENT CASE 5
• 90 yo woman brought in by her 90 yo woman brought in by her daughter (also your patient) for daughter (also your patient) for urinary incontinenceurinary incontinence
• Stands up to go to the bathroom and Stands up to go to the bathroom and voids on her clothes and the floor on voids on her clothes and the floor on the waythe way
• About 4 accidents per dayAbout 4 accidents per day• Moderately advanced Alzheimer’s Moderately advanced Alzheimer’s
dementiadementia• Refuses to wear pads (takes them off Refuses to wear pads (takes them off
and hides them)and hides them)• Drinks 2-3 Diet Pepsi’s per dayDrinks 2-3 Diet Pepsi’s per day
HistoryHistory
PATIENT CASE 5PATIENT CASE 5
• Repeats herself frequently during Repeats herself frequently during the examthe exam
• Slow, shuffling gaitSlow, shuffling gait• Mild atrophic vaginal mucosaMild atrophic vaginal mucosa• Soft fecal impactionSoft fecal impaction
• Urinalysis – normalUrinalysis – normal• PVR – 45 ccPVR – 45 cc
ExamExam
TestingTesting
PATIENT CASE 5PATIENT CASE 5
• Functional IncontinenceFunctional Incontinence– Prompted Voiding – Prompted Voiding –
• Before and after each meal, Q am, Before and after each meal, Q am, & Q HS& Q HS
• Q 2 hours even hours while awakeQ 2 hours even hours while awake– Stop CaffeineStop Caffeine– Consider Physical TherapyConsider Physical Therapy– If needed, pull-up diapers and hide If needed, pull-up diapers and hide
regular underwearregular underwear– Manage ConstipationManage Constipation– Consider Geriatric AssessmentConsider Geriatric Assessment
TreatmentTreatment
PATIENT CASE 5PATIENT CASE 5
• Daughter reports she is Daughter reports she is continent.continent.
• Didn’t realize she was Didn’t realize she was constipated, now daily BM constipated, now daily BM with prunes each morning.with prunes each morning.
• Didn’t need the pull-up Didn’t need the pull-up diapers since the prompted diapers since the prompted voiding schedule worked so voiding schedule worked so well.well.
Return VisitReturn Visit
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