EU Project Informatics Alignment Workshop

Imperial College LondonApril 24th-25th

Natalja Kurbatova (EMBL-EBI)eTOX

What is eTOX

• eTOX - Integrating bioinformatics and chemoinformatics for the development of Expert systems allowing the in silico prediction of toxicities (http://www.e-tox.net/project_summary.html).

• eTOX objectives:– Database building and management,– Ontologies and text mining techniques,– Chemistry and structure-based approaches for the molecular description of the

studied compounds,– Development and validation of QSARs (Quantitative structure–activity

relationship models), integrative models, expert systems and meta-tools.– etc.

• Funded by: IMI / EFPI in kind/ Other• Time frames: 7 years (01/01/2010 --- 31/12/2016)• Members:

– Pharma partners (13)– Academic groups (12) – Commercial Suppliers (5)

Data collected by eTOX

Specific needs for MyProject

• Data marshalling layer

• Version updates and compatibility

• Multi-omics data support

Specific needs for tranSMART instances at EMBL-EBI