EssenthyalTM is a homogeneous injectable hydrogel for medical use.It is indicated for deficit of soft tissues and it allows a long lasting correction and a natural look.

CompositionEssenthyalTM is a monophasic hyaluronic acid hydrogel.

IndicationsEssenthyalTM is suitable for temporary correction of congenital and acquired soft tissue deficits.

Innovative formulaThe hyaluronic acid used in our formulation is derived from Bacillus subtilis, a human nonpathogenic microorganism. The result is a high pure product free of contaminant DNA, proteins and pyrogens, with a decrease of unpredictable adverse reactions.

Long lasting effectEssenthyalTM is resistant to mechanical stress and it preserves its own mechanical properties, while maintaining an easy handling of injection; so it yields a very good result.

Biological safety and eficacy testsBoth in vitro and in vivo tests, in accordance with the relevantregulations, have demonstrated that EssenthyalTM is highly pure and biocompatible, non-mutagenic, non-toxic, non-sensitizing and resistant to mechanical stresses:• Chemical characterization, including FTIR and NMR spectroscopy• Mechanical characterization (rheology and texture analysis)• In vitro cytotoxicity• In vivo implantation test• Intracutaneous reactivity test• Acute systemic toxicity test• Delayed hypersensitivity test• Bacterial reverse mutation assay (Ames test)• In vitro Mammalian Chromosome Aberration Test• Degradation test

EUmaterials S.R.L.SS 7 Km 7+300, Cittadella della Ricerca72100 Brindisi, Italy

FeATuRes ADvANTAgesMonophasic hyaluronic acid hydrogelderived from human nonpathogenic bacteria

High performance and elasticityLow immunological response risk

Innovative technology for obtaining hyaluronic acid uses minimal media, no organic solvents and a highly efficient purification process

Very pure product

Texture similar to surrounding tissues Natural feeling

Injection technique EssenthyalTM can be injected with the techniques commonly used for other hyaluronic acid fillers.It is a mini-invasive procedure and a topical anesthetic administered to the site of injection is enough to avoid the pain.The augmentation usually lasts five-six months, depending on your life style, body reaction and quantity injected.

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