#ESOT2019 Advanced Programme · 2019-07-31 · — #ESOT2019 — 3 Dear Colleagues, Dear Friends,...

— #ESOT2019 — 1

19th Congress of the European Society for Organ Transplantation

September 15 - 18, 2019Copenhagen, Denmark

#ESOT2019 Advanced Programme

ECTORS European

Cell Therapy andorgan regeneration

Section

2 — #ESOT2019 —

TEN REasoNs To aTTENd1 Be inspired2 Drive progress3 Explore the edge of our current practice and

achievements4 Discuss with experts and innovative thinkers about

Why vs Why Not?5 Interact with peers and pave the way forward

together6 Master the latest trends of basic and translational

science

7 Explore how to manage career development8 Attend dedicated tracks to maximise the learning

experience9 Share your research and be selected for focused

discussions – guided and instructed by key opinion leaders in the field

10 Get engaged in this interactive meeting and take an active role in shaping the future of transplantation research and clinical practice

Who should aTTENd?The target audience for this conference includes all fields involved in health care and research with an affiliation in transplantation. This includes but is not limited to:

¢ Transplant surgeons¢ Physicians of all fields with an involvement in

transplantation¢ Coordinators, Nurses¢ General surgeons and clinicians with an interest in

transplantation

¢ Transplant scientists¢ Nutrition and rehabilitation specialists and

coordinators¢Transplant pharmacists¢Perfusionists

Further, health care professionals with an involvement in treatment of organ failure, cell therapy, tissue and regenerative medicine are warmly welcome to our conference.

FIVE PIllaRs oF ThE EsoT 2019 CoNGREss

— #ESOT2019 — 3

Dear Colleagues, Dear Friends,

The 19th Congress of ESOT will take place in Copenhagen, the beautiful capital of Denmark. The ESOT 2019 Congress will cover all areas of transplantation, both basic science and clinical aspects. Some of the major topics of the Con-gress will be: from ancient legends to modern miracles, the importance of advances in molecular medicine for solid organ transplantation, and tissue engineering. These, together with other hot topics from all areas of transplantation will be presented in a program developed by world leading transplant physicians, surgeons and scientists. Solid organ transplantation has a long history in Denmark. Kismeyer and Simonsen are among the real pioneers de-veloping Transplant Immunology since the early sixties. Since then, all types of organ transplantation have evolved in Denmark to high international standards. We are therefore delighted and honoured that ESOT selected Copenhagen for its prestigious Congress. Copenhagen is an ideal congress city, known to be a safe, eco-friendly and bike friendly capital city. It has extensive green areas and a harbor so clean that you can swim in it. Transportation from the modern congress centre to the city is easy and short, so time can be spent efficiently. After an intense day at the Congress, relaxation in cosy Copenhagen will be a delight. Get inspired by award winning new Nordic cuisine, the impressive mixture of historic and modern Danish design and architecture, Royal Castles, see the Little Mermaid or take a tour through the old canals. On behalf of the Danish Transplantation Society and on behalf of the Congress Organizing Committee we warmly welcome you to ESOT 2019 in Copenhagen.

Allan Rasmussen and Finn GustafssonCongress Chairs

Dear Colleagues, Dear Friends

We are truly delighted to cordially invite you to be Inspired and experience real Progress at the ESOT Congress in Co-penhagen, a transplant meeting of truly great scientific substance delivered in great ESOT style! The philosophy behind every ESOT Congress is that every two years we produce a totally New Congress in content and format; ESOT 2019 Copenhagen not only follows this rule but aspires to be the best transplant congress ever! ESOT 2019 Copenhagen is designed to be Your Congress, tailoring and targeting its content to the discipline that you serve, the stage of your career journey in transplantation and your professional aspirations. Knowledge will be delivered through a plethora of networking opportunities leading to new collaborations so that the end of the Congress will mark many new beginnings in transplantation. We aim to explore the edge of our current prac-tice and achievements and also challenge each other about great things that have not yet happened, ask ourselves, Why Not? And pave together the way forward. Looking at the hot topics of the Congress (which are just the appetisers for a great feast…), we will learn from history and each other, make patients active partners in our endeavours, vigorously debate our ethical conduct, take deep dives in the waters of basic and translational science so that we can bring to the surface clinical solutions, admit the moments we reached our clinical limits and explore how to push them further, debate and design innovation with realism and all in the context of our palpable and substantial professional development. Furthermore, the ESOT award winning Digital Congress Innovations have now reached new heights and they are designed to bring people together (even if they are not physically at the Congress!), maximise their interaction and advance their knowledge. Last but most certainly not least, all these are going to happen in Copenhagen, a dream city that can make those who adore classic fairy tales and the enthusiasts of modern miracles equally happy and in the Bella Conference Centre that is designed to make your time at the Congress Productive and Enjoyable. Join us in Copenhagen!Be Inspired and Drive Progress!

Vassilios Papalois and Allan RasmussenScientific Program Committee Chairs

4 — #ESOT2019 —

NEW aT #EsoT2019

Find Out What’s neW:

n Machine Perfusion and VAD Contestn Organ Reconditioningn Regenerative Medicinen Stem cells and Gene Editing: a disruptive weddingn ‘Omics’ technologies in Transplantationn The unthinkable donors and recipientsn The Patient definitionn Cross-specialty learningn Empowered transplanters can get to the TOPn How to navigate the environment of Regulatory authorities and Bodies

and much mOre On the FOrmat:

Campfires The chance to interact with the speaker and your peers in small group sessions based on informal

discussion.

Hottopictables Take advantage of valuable peer-to-peer learning with small, moderated discussions with your

peers on topics relevant to you.

EducationTrack Absorb the vision and expertise of Big Players at classroom-style learning sessions

TheBuddySystem Connect “First time” ESOT Congress participants with experienced attendees.

Arenas Debating cutting edge topics

— #ESOT2019 — 5

Table of content

6 Programme Overview

8 Committees

10 Legenda

12 Plenary sessions

12 State of the Art Sessions

13 Inspire & Drive Sessions

13 Education Tracks

14 MDT Sessions

14 Refresher

16 Speciality Update Symposia

19 Scientific programme

43 ESOT 2019 Congress Awards

44 Registration

45 Copenhagen informations

45 Venue

46 Partners

sCIENTIFIC PRoGRammE oVERVIEW

9:00 12:50

SPECIAlTy UPDATE SyMPOSIA

edtcO ectta eLita ePita eKita YPt Bsc Vca ectOrs etahP eLPat

13:30 14:30

edu tracK 1 Immunology

ABCs and beyond

mdt 1 It’s all about

safety

eLeVatOr Pitch

EP 01 reFresher 1 Translational Science

FOcus GrOuPsFG 01 - FG 05

mOderated e-POster

MP 01MP 04

BrieF OraL sessiOns

BOS 01BOS 05

14:30 15:00

15:10 16:40

cOrPOrateParaLLeL

sYmPOsium

cOrPOrateParaLLeL

sYmPOsium

sPeciaL sessiOn Antibody mediated rejection and complement. Brothers in

arms?

JOint sessiOn

esOt-iPta

BanFF meetseKita:

from histology to bedside

mdt 2The great ECMO

challenge!(Joint EDTCO/ECTTA/BSC)

eu traincaLLinG

17:0019:00

PLenarY 1Be inspired, be driven

19:00 20:00 Networking Cocktail

mOndaY, sePtemBer 167:30 8:00

edu tracK 2 Tolerance is here to stay

8:00 9:00

FuLL OraL sessiOnsOS 01 - OS 06

BrieF OraL sessiOnsBOS 06 - BOS 07

9:10 10:40

sOta 1Microbiome in transplantation:

friend or foe?

sOta 2Organ allocation algorithm

sOta 3How to choose the right research model

10:40 11:10 Break

11:10 11:40

insPire & driVe 1How to get to the top

transPLantresearch

chaLLenGe

reFresher 2learning from neighbouring

specialities


FOcus GrOuPsFG 06 - FG 1011:40

12:40cOrPOrate (HANDS-ON)

WOrKshOP

13:00 14:00

mOderated e-POsterMP 05 - MP 08

cOrPOrate ParaLLeL

sYmPOsium

cOrPOrate ParaLLeL

sYmPOsium

cOrPOrate ParaLLeL

sYmPOsium

esOt ViPVIP 01

YPt Future Leaders

On staGe

BrieF OraL sessiOnsBOS 08 BOS 10

14:05 15:35

PLenarY 2single cells omics: generating an atlas to chart transplant organs

15:35 16:00 Break

16:00 16:30

insPire & driVe 2Evidence based practice is killing

the art of medicine

edu tracK 3Xenotransplantation,

soon a reality?

cOrPOrate(HANDS-ON) WOrKshOP


BrieF OraL sessiOns

BOS 11 - BOS 13

eLeVatOr Pitch

EP 0216:30 17:0017:00 17:30 reFresher 3

Big Data

cOrPOrate(HANDS-ON) WOrKshOP


BrieF OraL sessiOns

BOS 14 - BOS 16esOt

GeneraLassemBLY

17:30 18:00

18:05 18:3018:30 19:35

sundaY, sePtemBer 15

cOrPOrate PLenarY sYmPOsium

SATURDAy, SEPTEMBER 14uems/esOt

eXams

tuesdaY, sePtemBer 177:30 8:00

edu tracK 4 Machine perfusion

goes prime time8:00 9:00



9:10 10:40

sOta 4 Pluripotent Stem Cells Meet Genome

Editing: a disruptive wedding

sOta 5 DCD: push the boundaries

sOta 6Small Patients, Big Challenges

10:40 11:10 Break

11:10 11:40

insPire & driVe 3 Relight my fire

reFresher 4 Inflammation


cOrPOrate (HANDS-ON) WOrKshOP

FOcus GrOuPsFG 11 - FG 15

eLeVatOr Pitch

EP 0311:40 12:40


13:00 14:00

cOrPOrate ParaLLeL

sYmPOsium

cOrPOrate ParaLLeL

sYmPOsium

cOrPOrate ParaLLeL

sYmPOsiumesOt ViP

VIP 02



14:05 15:35

PLenarY 3Perfect organ preservation and reconditioning - an elusive dream?

15:35 16:00 Break

16:00 17:00

insPire & driVe 4 Engineering the future

edu tracK 5 Ischemia

reperfusion injury – still a

challenge?

mdt 3The unthinkable donor/recipient


FOcus GrOuPs

FG 16 - FG 20


BrieF OraL sessiOns

BOS 23 - BOS 25

cOrPOrate ParaLLeL

sYmPOsium


17:05 17:30 cOrPOrate

ParaLLeLsYmPOsium

cOrPOrate ParaLLeL

sYmPOsium

eLeVatOr Pitch

EP 04


17:3018:0518:0518:35 turninG

research intO an aGent OF

chanGe off-site event

live from Stanford

University

BrieF OraL sessiOns

BOS 26 - BOS 28

18:4019:1019:10 19:4019:40 20:00

WednesdaY, sePtemBer 187:30 8:00

edu tracK 6Regenerative Transplantation

8:00 8:30 FuLL OraL sessiOns

OS 43 - OS 48Os LB BrieF OraL sessiOns

BOS 29 - BOS 318:30 9:00

9:10 10:40

sOta 7 Pharmaco Genomics.

Are we ready for implementation into clinical practice?

sOta 8 New imaging techniques

sOta 9Transplant success:

the patient’s definition

10:40 11:10 Break

11:10 13:00

PLenarY 4 & PresidentiaL sessiOnDealing with organ failure: a change in the direction of travel?

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EsoT 2019 CoPENhaGEN CommITTEEs

Congress ChairsFinn Gustafsson, Copenhagen, Denmarkallan rasmussen, Copenhagen, Denmark

Scientific ProgrammeCOMMITTEE CHAIRSVassilios Papalois, London, United Kingdomallan rasmussen, Copenhagen, Denmark

MEMBERSerik Berglund, Stockholm, Sweden ❚ menna clatworthy, Cambridge, United Kingdom ❚

constantino Fondevila, Barcelona, Spain ❚ Finn Gustafsson, Copenhagen, Denmark ❚ Luuk hilbrands, Nijmegen, The Netherlands ❚ Franz immer, Bern, Switzerland ❚ ina Jochmans, Leuven, Belgium ❚ nicos Kessaris, London, United Kingdom ❚ henri Leuvenink, Groningen, The Netherlands ❚ Gavin Pettigrew, Cambridge, United Kingdom ❚ Lorenzo Piemonti, Milan, Italy ❚ thomas resch, Innsbruck, Austria ❚ david rodriguez-arias, Granada, Spain ❚ søren schwartz sørensen, Copenhagen, Denmark ❚ Luca toti, Rome, Italy ❚ andreas Zuckermann, Vienna, Austria

Organising Executive CommitteeVassilios Papalois, London, United Kingdom ❚ allan rasmussen, Copenhagen, Denmark ❚ annalisa Ponchia, Padova, Italy ❚ erik Berglund, Stockholm, Sweden ❚ menna clatworthy, Cambridge, United Kingdom ❚ ina Jochmans, Leuven, Belgium ❚ søren schwartz sørensen, Copenhagen, Denmark ❚ Luca toti, Rome, Italy

Local CommitteeFinn Gustafsson, Copenhagen ❚ mads hornum, Copenhagen ❚ Pernille Kofoed-nielsen, Aarhus ❚ Paul Krohn, Copenhagen ❚ carina Lund sørense, Hillerød ❚ michael Perch, Copenhagen ❚ Vibeke rømming sørensen, Copenhagen ❚ nicolai schultz, Copenhagen ❚ helle c. thiesson, Odense

Ambassadors International Committeeellis morris randall, Carmel, USA ❚ hassan argani, Tehran, Iran ❚ ahn curie, Seoul, South Korea ❚ roslyn B. mannon, Birmingham, USA ❚ elmi muller, Cape Town, South Africa ❚ John s. Gill, Vancouver, Canada ❚ Krishnakumar madhavan, Singapore,❚ david sutherland, Minneapolis, USA ❚ arvinder soin, Gurgaon, India ❚ Waldo conception, Palo Alto, USA

The ESOT Council

stefan schneeberger, President ❚ thierry Berney, Past President ❚ Vassilios Papalois, President-Elect ❚ Luciano Potena, Treasurer ❚ Gabriel Oniscu, Secretary ❚ Luca segantini, CEO

— #ESOT2019 — 9

WITH COUNCIllORS:

Oriol Bestard, Barcelona, Spain ❚ umberto cillo, Padova, Italy ❚ Frank dor, London, United Kingdom ❚ Luuk hilbrands, Nijmegen, The Netherlands ❚ maarten naesens, Leuven, Belgium ❚ Xavier rogiers, Ghent, Belgium ❚ Olivier thaunat, Lyon, France

AND

ivan Knezevic, ECTTA Chair ❚ robert Langer, EKITA Chair ❚ christophe duvoux, ELITA Chair ❚ eelco de Koning, EPITA Chair ❚ david Paredes, EDTCO Chair ❚ emma massey, ELPAT Chair ❚ henri Leuvenink, BSC Chair ❚ raj thuraisingham, EC Chair ❚ Gerald Brandacher, VCA Chair ❚ marjo Van helden, ETAHP Chair ❚ Zeeshan ahktar, YPT Chair ❚ Liset Pengel, CET ❚ rainer Oberbauer and thomas Wekerle, TI Editors in Chief

10 — #ESOT2019 —

lEGENda

Types of sessionsAcronym & colour code

nSUS – Specialty Update SymposiumAt Speciality Update Symposia leading specialists are invited to present as part of a deep dive into a specific organ or field within transplantation. Sessions are developed in collaboration with the relevant ESOT Section or Committee. All transplant professionals are invited to start their congress experience by participating in the Speciality Update Symposia of their choice.

nPL – Plenary Session The whole congress gathers for Plenary sessions to experience powerful out-of-the-box presentations delivered by expert speakers from inside and outside medical science. Plenary sessions energise and inspire the ESOT community while raising important issues and asking crucial questions that reframe the past and define the future of transplantation.

nSOTA – State of the Art SessionState of the Art sessions offer participants an opportunity to gain a better understanding of the best methods and the most robust procedures in transplantation. This is a unique opportunity to get a global perspective on transplantation and learn from a diverse group of peers.

nID – Inspire & Drive Inspiring minds and driving progress (the motto of the congress) is the focus on the Inspire & Drive sessions. The sessions explore the benefits of mentoring among other ways of keeping young transplant professionals driven and inspired to develop in the field of transplantation.

nEDU – Education Track Education Track sessions address the always important fundamentals of transplantation. The sessions are aimed at transplant professionals looking to learn or relearn the elementary aspects of transplantation. Sessions start with a knowledge gap assessment, continue with presentations from experts and conclude with an assessment on the topics covered.

nMDT – Multidisciplinary Team SessionMDT sessions bring together the multiple fascinating aspects of transplantation. Key topics are presented and discussed from the different perspectives, typical of multi-disciplinary teams. The skills discussed are easily transferable to other fields, even outside medical science. MDT sessions are a prime example of what makes organ transplantation such a rich and unique field.

nR – Refresher Session Refresher sessions offer a fresh view on some of the fundamentals of transplantation. Experienced transplant professionals share new perspectives on some of the most important and well-established topics in transplantation.

nOFF – Offsite event

nSS – Special SessionSessions with special focus on different matters in transplantation and/or collaborations with other medical societies or bodies linked to transplantation.

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Abstracts Driven sessions

Types of audience Acronym & colour code based on ESOT Sections & Committees

lECTTA Cardio Thoracic transplant professionals

lEKITA Kidney transplant professionals

lELITA Liver and Intestine transplant professionals

lEPITA Pancreas and Islet transplant professionals

lEDTCO Donation & Transplant coordinators

lELPAT Ethical, Legal and Psychosocial Aspects of Organ Transplantation professionals

lECTORS Cell Therapy and Organ Regeneration transplant professionals

lBSC Basic Science transplant professionals

lVCA Vascularized Composite Allotransplantation professionsals

lETAHP Transplant Allied Healthcare Professionals

lYPT Young Professionals in Transplantation

Full Oral Presentation7 minutes long (5 minutes for presentation, 2 minutes Q&A’s).

Focus Group10 minutes long (2 minutes for presentation, 8 minutes moderated discussion-Highly scored abstracts to be allocated for top-level moderated group discussion and SWOT analysis of the submitted work).

Brief Oral3 minutes long (2 minutes for presentation, 1 minute Q&A’s).

Elevator Pitch1 slide 1 minute to convince 3 judges, if you succeed you can extend your presentation up to 5 minutes in total.

Moderated e-Poster5 minutes long (1 minute introduction, 4 minutes discussion).

e-PostersYour research available to all delegates of the ESOT 2019 via interactive mobile app, which allows to book individual appointments and discuss your work.

ViP – Video Presentation Session

MPLab – Machine Perfusion Lab

12 — #ESOT2019 —

PL 1 Be insPired, Be driVen - A NEW PERSPECTIVE ON THE FUTURE OF MEDICINE: IS ORGAN TRANSPlANTATION GOING TO BE OUT OF BUSINESS?

PL 2 sinGLe ceLLs Omics GeneratinG an atLas tO chart transPLant OrGans

PL 3 PerFect OrGan PreserVatiOn and recOnditiOninG – an eLusiVe dream?

PL 4 & PresidentiaL sessiOn - deaLinG With OrGan FaiLure: a chanGe in the directiOn OF traVeL?

PlENaRy sEssIoNs (Pl)

sOta 1 micrOBiOme in transPLantatiOn: Friend Or FOe?

sOta 2 OrGan aLLOcatiOn aLGOrYthm

sOta 3 hOW tO chOOse the riGht research mOdeL

sOta 4 stem ceLLs and Gene editinG - PlURIPOTENT STEM CEllS MEET GENOME EDITING: A DISRUPTIVE WEDDING

sOta 5 dcd: Push the BOundaries

sOta 6 smaLL Patients, BiG chaLLenGes

sOta 7 PharmacO GenOmics – ARE WE READy FOR IMPlEMENTATION INTO ClINICAl PRACTICE?

sOta 8 neW imaGinG techniQues

sOta 9 transPLant success: the Patient’s deFinitiOn

sTaTE oF ThE aRT sEssIoNs (soTa)

— #ESOT2019 — 13

INsPIRE & dRIVE sEssIoNs (Id)

insPire & driVe 1 hOW tO Get tO the tOP

insPire & driVe 2 eVidence Based Practice is KiLLinG the art OF medicine

insPire & driVe 3 reLiGht mY Fire - “GET BACk OUT THERE AND TRy IT AGAIN.”

insPire & driVe 4 enGineerinG the Future

EduCaTIoN TRaCks (Edu)

tracK 1 immunOLOGY: aBcs and BeYOnd

tracK 2 tOLerance is here tO staY

tracK 3 XenOtransPLantatiOn - sOOn a reaLitY?

tracK 4 machine PerFusiOn GOes Prime time

tracK 5 ischemia rePerFusiOn inJurY – stiLL?

tracK 6 reGeneratiVe transPLantatiOn

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mdT sEssIoNs (mdT)

mdt 1 it’s aLL aBOut saFetY

mdt 2 the Great ecmO chaLLenGe

mdt 3 the unthinKaBLe dOnOr/reciPient

REFREshER (R)

reFresher 1 transLatiOnaL science

reFresher 2 LearninG FrOm neiGhBOurinG sPeciaLities

reFresher 3 BiG data

reFresher 4 inFLammatiOn

— #ESOT2019 — 15

sPECIalITy uPdaTE symPosIa (sus)

about ectOrsGOaLs To facility the integration of regenerative medicine in clinical organ transplantation.aim Provide a forum for discussing and stimulating novel developments in the fields of cellular therapies in organ transplantation, organ reconditioning / regeneration and generation of new organs from stem cells and biomaterialsLearninG OBJectiVes Participants will be updated on the state of the art in regenerative med-icine in the field of organ transplantation.tarGet audience Basic scientists, clinicians, corporations interested in stem cell therapy, or-gan reconditioning and organ regeneration

ECTORS European

Cell Therapy andorgan regeneration

Section

about BscThe Basic Science Committee promotes Basic science in transplantation in Europe.GOaLs Translation of innovation into clinical activity; Communication between basic scientists and clinicians; Collaboration between laboratories in Europe.tarGet audience Basic Scientists, Transplant immunologists, Regenerative Medicine re-searchers, Transplant physicians.

about VcaVascularized Composite Allotransplantation (VCA) has opened a new chapter in the field of transplantation, reconstructive, and restorative surgery. This committee brings together 8 repre-sentatives of major European teams at the forefront in this field. GOaLs Our goal is to raise the scientific and clinical development oVf ascularized Composite Allotransplantation (VCA) in Europe and to serve as a platform for scientists and clinicians for information and ex change.aim This SUS aims to provide an update on clinical outcomes and latest developments in the field of VCA including upper extremity, face, and uterus transplantation. In addition, we will pro-vide and outlook on how latest developments in the area of organ preservation and regenera-tive medicine might shape the future of this innovative field.LearninG OBJectiVes At the end of this SUS the participants will have learned about out-comes (functional, immunological, psychosocial), as well as complications and potential pit-falls in the world experience with VCA including upper extremity, face, and uterus transplanta-tion. The participates will learn to assess the pros and cons of different immunomodulatory approaches in VCA and get a perspective on the future of the field.tarGet audience Surgeons, physicians, researchers, transplant coordinators.

about ecttaBringing back to life heart and lung failure patients: it is time to move away from transplanta-tion? Will DCD donation and new frontiers for organ preservation and allocation improve surviv-al and QOL of patients suffering heart and lung failure.?Establish a role for mechanical support during end-stage heart and lung failure and the relation-ship with bioengineered organs, regenerative medicine and transplantation.Improve the long term follow-up: the role of precision medicine in the management of thoracic transplantation. GOaLs A survey will involve the ECTTA members and affiliates in the setup of the program look-ing at a balanced match between open discussion and state of the art lectures.aim The meeting will deal with the recent impulse that Thoracic transplantation has received in Europe from DCD donation and from the new techniques of organ preservation aiming at pre-serve more vulnerable organs.Describe the right use of mechanical replacement or support of thoracic organs (ECMO, VAD, ar-tificial lungs) and thoracic transplantation in Europe aiming to enlarge the number of patients treated and their survival and QOL.

16 — #ESOT2019 —

The faculty will also highlight the limitations in the improvement of exercise capacity of patients receiving thoracic transplantation and mechanical circulatory support and possible solutions to improve outcomes of destination therapy.LearninG OBJectiVes A well balanced mixture of state of the art lectures and open discussion will allow participants to deal with the new solutions aiming to treat heart and lung failure in the upcoming future.tarGet audience transplant professionals (cardiologists, pneumologists, surgeons, anaes-thesiologists, VAD and transplant coordinators, expert in rehab medicine).

about eKitaEKITA is the kidney section of ESOT and deals with all aspects of renal transplantation. As a European platform, EKITA supports research, education and clinical work in this area. Further-more, EKITA is highly ambitious in preparing policies and creating transnational interactions to advance renal allografting in all European member states.GOaLs The main goal of EKITA is to improve quality of life of people with ESRD by advancing all aspects of kidney transplantation. aims The ultimate aim of EKITA is the optimization of renal transplantation trough activities in research, education, clinical collaboration and health policy.LearninG OBJectiVes To provide an overview on T & B-cell interaction. tarGet audience Transplant surgeons and physicians, nephrologist, immunologists at all stages of training and expertise.

about eLitaThe European Liver and Intestine Transplantation Association is a multi-disciplinary Society of health care professionals in liver and intestine transplantation which is the official professional society delegated by ESOT for liver and intestine transplantation in Europe.GOaLs To provide a range of educational activities, stimulate discussion and influence Euro-pean legislation in liver and intestine transplantation. To stimulate clinical research and publi-cations from analysis of the registry, in partnership with the European Liver Transplant Registry.aim Our aim is to set guidelines and standards and to provide education and support in liver and intestine transplantation within the European Countries and beyond.LearninG OBJectiVes To learn about the current state of different types machine preserva-tion in liver transplantation and normothermic regional perfusion in donors after circulatory death as well in the currents trends and innovations in immunosuppression after liver trans-plantation.tarGet audience Liver transplant surgeons and hepatologists, HPB surgeons and general hepatologists, specialist nurses in liver transplantation, HPB, hepatology and oncology.

about ePitaThe European pancreas and Islet Transplantation Association is a section of ESOT founded to provide a Forum for the pancreas and islet transplantation community in Europe.GOaLs To facilitate the exchange of information of the field of pancreas and islet transplantation.aim The aim of EPITA is to contribute to the development of the pancreas and islet transplan-tation field and of alternate forms of beta-cell replacement therapy for the benefit of patients suffering from type 1 diabetes.LearninG OBJectiVes The participant will know what donor characteristics to focus on in the decision to use marginal donors for pancreas or islet transplantation, how to monitor islet and pancreas graft rejection and to implement the diagnostic tools to be able to assess the success of pancreas and islet transplantation.Target audience: Surgeons, nephrologists, diabetologists, transplant coordinators interested in pancreas and islet transplantation. tarGet audience Transplant surgeons and physicians, transplant coordinator, nurses and medical student with an interest in transplantation of pancreas and islets.

sPECIalITy uPdaTE symPosIa (sus)

— #ESOT2019 — 17

about edtcOEDTCO is a section within ESOT dedicated to donation and procurement activities.GOaLs Increase organ and tissue availability. Ensure the quality and safety of organs and tis-sues for transplantation. Optimise the safety of living donors and care for deceased donors and their relatives. Optimise potential recipient care and follow-up through effective clinical coordination.aim To establish clinically effective programmes in organ and tissue donation, procurement and transplantation by supporting and representing all healthcare professionals involved in the process.tarGet audience Healthcare professionals involved in intensive care and emer- gency medicine, end of life care, organ and tissue donation and coordination. Patient, family and society representatives, EU commissioners.

about eLPatELPAT is a section of ESOT dedicated to the ethical, legal and psychosocial aspects of organ donation and transplantation.GOaLs ELPAT goals include organizing symposia and conferences, as well as initiating and par-ticipating in research, and disseminating knowledge through publications and events.aim ELPAT aims to stimulate collaboration, innovation and knowledge exchange on ethical, le-gal and psychosocial aspects of transplantation. We bring continuity and structure to the dia-logue on these issues and to contribute to development of clinical practice, research and policy. LearninG OBJectiVes A description of what a participant will achieve at the conclusion of the programme. When writing outcomes, it is helpful to use verbs that are measurable or that de-scribe an observable action. The best learning objectives will include a description of the condi-tions (“when given x, you will be able to…”) and the acceptable performance level. After following these lectures participants will have greater knowledge and understanding of current ethical, legal and psychosocial challenges in deceased and living donation.tarGet audience Physicians, nurses, ethicists, lawyers, psychologists, coordinators.

about etahPETAHP reaches out to nurses (e.g. clinical nurses, advanced practice n urses and nurse co-ordinators (recipient care), psychologists, physical therapists, occupational therapists, social workers, dieticians, pharmacists and other disciplines working in the field of transplantation.GOaLs Within ETAHP, nurses and allied healthcare professionals throughout Europe will be united to ensure the best care possible to all transplant patients, with the aim to optimize patient outcomes.aims We will do so by creating a strong European interdisciplinary platform to: share evidence based knowledge; exchange experiences and provide training; facilitate research and clinical collaborations; set the standards for the quality of care in transplant nursing and for allied health professionals.LearninG OBJectiVes After the SUS the participant will be able to identify and overcome barriers for implementation of knowledge into transplant practice and to recognize and de-velop leadership behaviours that support EBP, manage risk associated with medicine use, re-duce errors and incident reporting (open and honest culture/organisations with memory etc).tarGet audience Nurses and Allied Healthcare Professionals in Transplantation.

18 — #ESOT2019 —

saturdaY, sePtemBer 14

09:00 – 19:001st ectOrs meetinGThe content of this meeting is centred around the state of the art of regenerative medicine in organ transplantation and its road to clinical application.

09:00 – 09:30 WeLcOme and reVieW 2008 - 2018 Marc Dahlke, Regensburg, Germany; Martin Hoogduijn, Rotterdam, The Netherlands

09.30 – 11.00 session 1: stem ceLLs neW deVeLOPments Chairs: Marc Dahlke, Regensburg, Germany; Martin Hoogduijn, Rotterdam, The Netherlands

msc mechanisms of action Francesco Dazzi, London, United Kingdom msc in organ injury Rafael kramann, Aachen, Germany Liver organoids from adult stem cells luc van der laan, Rotterdam, The Netherlands

11.00 – 11.30 COFFEE BREAK

11.30 – 13.00 sessiOn 2: ceLL theraPY cLinicaL triaLsChairs: Marcella Franquesa, Barcelona, Spain Christian Johnson, Regensburg, Germany

msc in clinical kidney transplantation Norberto Perico, Bergamo, Italy From phase 1 to phase 2 clinical trials with msc in kidney transplantation Marlies Reinders, Leiden, The Netherlands Lessons from other phase 1 trials Jens kastrup, Copenhagen, Denmark

13.00 – 14.00 LUNCH

14.00 – 15.30 sessiOn 3: OrGan recOnditiOninGChairs: Sarah Hosgood, Cambridge, United Kingdom; Marlies Reinders, Leiden, The Netherlands Kidney machine perfusion Sarah Hosgood, Cambridge, United Kingdom Liver machine perfusion Nicholas Gilbo, Leuven, Belgium regeneration on the pump Rutger Ploeg, Oxford, United Kingdom

15.30 – 16.00 COFFEE BREAK

16.00 – 17.30 sessiOn 4: cOrPOrate sessiOnChairs: Martin Hoogduijn, Rotterdam, The Netherlands; Chris Johnson, Regensburg, Germany

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09:00 – 10.00 sessiOn 5: aBstract PresentatiOnsChairs: Federica Casiraghi, Bergamo, Italy; Marc Dahlke, Regensburg, Germany

10.00 – 10.50 Keynote lecture: the use of pluripotent stem cells for organ regenerationNuria Montserrat, Barcelona, Spain

10.50 – 11.20 COFFEE/TEA

11.20 – 12.50JOint sessiOn With Vca and BscVca QuO Vadis?

11:20 – 11:50 advances in organ preservation and machine perfusion: potential impact on VcaAnnemarie Weissenbacher, Oxford University, United Kingdom / Innsbruck Medical University, Austria

11:50 – 12:20 thinking outside the box: combining Vca and regenerative medicine?Robert Rieben, Bern, Switzerland

12:20 – 12:50 cell-based immunoregulation and tolerance induction: are we getting any closer?Fadi Issa, Oxford University, United Kingdom

12.50 CLOSING

09:00 – 12:50 Vca specialty update symposiumOutcOmes in Vca

09:00 – 11:00 sessiOn 1: the GOOd, the Bad, and the uGLY

09:00 – 09:30 upper extremity transplantationChristina kaufman, Louiseville, United States

09:30 – 10:00 Face transplantationlaurent lantieri, Paris, France

10:00 – 10:30 uterus transplantationMatt Brannstrom, Gothenburg, Sweden

10:30 – 11:00 immunomodulatory protocolsGerald Brandacher, Baltimore, United States

11:00 – 11:20 COFFEE BREAK

11.20 – 12.50JOint sessiOn With Bsc & ectOrsVca QuO Vadis?

11:20 – 11:50 advances in organ preservation and machine perfusion: potential impact on VcaAnnemarie Weissenbacher, Oxford University, United Kingdom / Innsbruck Medical University, Austria

11:50 – 12:20 thinking outside the box: combining Vca and regenerative medicine?Robert Rieben, Bern, Switzerland

12:20 – 12:50 cell-based immunoregulation and tolerance induction: are we getting any closer?Fadi Issa, Oxford University, United Kingdom

12.50 CLOSING


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09:00 – 12:50 ectta specialty update symposium

09:00 – 09:40 tO die Or nOt tO die?Chair: Arne Neyrinck, Leuven, Belgium; David Paredes, Barcelona, Spain

09:00 – 09:10 Physiological benefitDavid Paredes, Barcelona, Spain

09:10 – 09:20 ethical counterpartsEline Bunnick, Rotterdam, The Netherlands

09:20 – 09:40 discussion

09:40 – 10:20 nrP dO nOt harm mY OrGans Chair: Michiel Erasmus, Groningen, The Netherlands; Edouard Sage, Paris, France

09:40 – 09:50 Over the diaphragm Stephen large, Papworth, United Kingdom

09:50 – 10:00 under the diaphragm Benoit Barrou, Paris, France



10:40 – 11:35 Part 1 Chair: Robin Vos, Leuven, Belgium; Andreas Zuckerman, Vienna, Austria

10:40 – 10:55 Over europe organ exchangeJacqueline Smiths, Leiden, The Netherlands

10:55 – 11:05 Xenotransplantation is the future of heart transplantation Sebastian Michel, Munchen, Germany

11:05 – 11:20 Bioengineered heart and lungsDarcy Wagner, Lund, Sweden

11:20 – 11:35 Q&a

11:35 – 12:50 Part 2Chair: Cristiano Amarelli, Naples, Italy; Johan Nilsson, Lund, Sweden

11:35 – 11:50 Patient-LVad interactionPia Jury, Astsana, Kazakhstan

11:50 – 12:05 Towards the artificial lung: technical limitations and future opportunities Simon Sonntag, Aachen, Germany

12:05 – 12:20 mechanical biventricular optionArnt Fiane, Oslo, Norway

12:20 – 12:50 Panel interactive debate: machines will overcomePRO: mechanical heart is already hereJan Schmitto, Hannover, GermanyCON: transplant of biological organs is still invincibleIvan knezevic, Ljubljana, Slovenia

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09:00 – 12:50 eLita specialty update symposium

machine PerFusiOn and immunOsuPPressiOn in LiVer transPLantatiOn – the Best FrOm BOth WOrLds09:00 – 09:05 intrOductiOn

Christophe Duvoux, Paris, France

9.05-10.50 sessiOn 1: machine cOntestChairs: Constantino Fondevila, Barcelona, Spain; Wojciech Polak, Rotterdam, The Netherlands

rOund 1 - cOLd Vs Warmhypothermic machine perfusion vs normothermic machine perfusion

09:05 – 09:20 hypothermic – cold is cool!Presentation by junior – Otto van leeuwen, Groningen, The Netherlands Mentor: Robert Porte, Groningen, The Netherlands

09:20 – 09:35 normothermic – warm is sexy!Presentation by junior – Rohit Gaurav, Cambridge, United Kingdom Mentor: Chris Watson, Cambridge, United Kingdom

09:35 – 09:50 What’s is this fuzz about? Just rewarm it!Presentation by junior – Charlotte von Horn, Essen, Germany Mentor: Thomas Minor, Essen, Germany

09:50 – 10:10 debate supported by mentorsRobert Porte, Groningen, The Netherlands & Christopher Watson, Cambridge, United Kingdom & Thomas Minor, Essen, Germany

rOund 2regional perfusion vs ex-situ perfusion in dcd

10:10 – 10:25 normothermic regional perfusion – let’s asses the liver in the donorPresentation by junior – Ahmed Sherif, Edinburgh, United Kingdom Mentor: Gabriel Oniscu, Edinburgh, United Kingdom

10:25 – 10:40 ex-situ perfusion – be quick and do it ex-situ!Presentation by junior – Nicholas Gilbo, Leuven, Belgium Mentor: Ina Jochmans, Leuven, Belgium

10:40 – 10:50 debate supported by mentorsGabriel Oniscu, Edinburgh, United Kingdom & Ina Jochmans, Leuven, Belgium


11.10 – 12.50 sessiOn 2: 30 Years OF immunOsuPPressiOn: is there such a thinG as PrOtOcOL immunOsuPPressiOn in LiVer transPLantatiOn?Chairs: Marina Berenguer, Valencia, Spain; Giacomo Germani, Padova, Italy

11.10 – 11.30 individualized immunosuppression: when and how Manuel Rodriguez Peralvarez, Cordoba, Spain

11.30 – 12.10 antibody mediated rejection: a real problem in Lt?PATHOLOGIST POINT OF VIEWMylene Sebagh, Paris, France CLINICIAN POINT OF VIEW Christophe Duvuox, Paris, France

12.10 – 12.30 Risks and benefits associated with minimization of immunosuppressionPatrizia Burra, Padova, Italy

12.30 – 12.50 establishing the net status of immunosuppression: the holy grail of transplantationAlberto Sanchez Fueyo, London, United Kingdom

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09:00 – 12:50 eKita specialty update symposium

09:00-10:40 sessiOn 1: – interactiOn OF B &t-ceLL aLLOimmunitYChairs: Robert langer, Linz, Austria; luuk Hilbrands, Nijmegen, The Netherlands

09:00 – 09:20 t & B-cell interaction Gavin Pettigrew, Cambridge, United Kingdom

09:20 – 09:40 complement system – novel insights in alloimmunityOlivier Thaunat, Lyon, France

09:40 – 10:00 Lymphocyte receptor repertoire – new opportunitiesRainer Oberbauer, Vienna, Austria

10:00 – 10:20 eplet matching. how to and is it better?Nils lachman, Berlin, Germany

10:20 – 10:40 spontaneous operational tolerance – does it exist?Annick Massart, Brussels, Belgium


11:00-12:50 sessiOn 2: – cOmPLicatiOn manaGement in the PatientChairs: Gabriel Oniscu, Edinburgh, United Kingdom; lucrezia Furian, Padova, Italy

11:00 – 11:25 treatment of aBmr – is there any? Menna Clathworthy, Cambridge, United Kingdom

11:25 – 11:50 the multiple transplant patient – what are the challenges?Maria Irene Bellini, London, United Kingdom

11:50 – 12:15 non-technical approaches to management of surgical complicationsNizam Mamode, London, United Kingdom

12:15 – 12:40 Practicability of the COMMIT guidelines for the kidney graft Franco Citterio, Rome, Italy

12:40 – 12:50 Past, Present and Future of eKitaRobert langer, Linz, Austria

09:00 – 12:50 ePita specialty update symposium

09:00 – 10:30 sessiOn 1: – marGinaL dOnOrsChairs: Helmut Arbogast, Heidelberg, Germany; Roger lehmann, Zurich, Switzerland

09:00 – 09:30 Where have all the pancreas gone? Steve White, Newcastle, United Kingdom

09:30 – 10:00 expanding donor characteristics: results from the eXPand trialStefan Farkas, Regensburg, Germany

10:00 – 10:30 using dcd pancreas for islet isolationMarten Engelse, Leiden, The Netherlands


11:00 – 12:50 sessiOn 2: – mOnitOrinG reJectiOn and OutcOme assessmentChairs: Eelco de koning, Leiden, The Netherlands; Julie kerr-Conte, Lille, France

11.00 – 11.30 How to close the gap in pancreas graft outcome between SPK and solitary pancreas Tx?Thierry Berney, Geneva, Switzerland

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11.30 – 12.00 Islet graft monitoring for rejection Marie-Christine Vantyghem, Lille, France

12.00 – 12.30 Defining the outcome of pancreas and islet graft functionMichael Rickels, Philadelphia, United States

12:30 – 12:50 Q&a

09:00 – 12:50 edtcO specialty update symposium

09:00 – 09:40 tO die Or nOt tO die?Chair: Arne Neyrinck, Leuven, Belgium; David Paredes, Barcelona, Spain

09:00 – 09:10 Physiological benefitDavid Paredes, Barcelona, Spain

09:10 – 09:20 ethical counterpartsEline Bunnick, Rotterdam, The Netherlands


09:40 – 10:20 nrP dO nOt harm mY OrGans Chair: Michiel Erasmus, Groningen, The Netherlands; Edouard Sage, Paris, France

09:40 – 09:50 Over the diaphragm Stephen large, Papworth, United Kingdom

09:50 – 10:00 under the diaphragm Benoit Barrou, Paris, France


10:20 – 10:40 COFFEE BREAK (&split)

11:00 – 11:20 expanded organ donor TBA

11:20 – 12:00 Organ donation – 3 challenge cases

12:00 – 12:20 expanded tissue donor

12:20 – 12:50 tissue donation – 2 challenge cases

09:00 – 12:50 eLPat specialty update symposium

chaLLenGinG the mindset On dOnatiOn09.00 – 10.30 sessiOn 1

Chairs: Antonia Cronin, London, United Kingdom; Emma Massey, Rotterdam, The Netherlands

09:00 – 09:30 death determination in dcd and dBd.Anne Dalle Ave, Lausanne, Switzerland

09:30 – 10:00 should we facilitate organ donation by patients who wish to die? ethical and legal boundaries.Penney lewis, London, United Kingdom

10:00 – 10:30 Opinion polls, public perception and practice: how do the public view opt-in versus opt-out?David Rodriguez-Arias, Granada, Spain


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09:00 – 12:50 etahP specialty update symposium

09.00 – 12.50 Fasten YOur seatBeLts- hOW tO JOin the ride OF eVidence Based Practicethe art of overcoming barriers for eBP

09:00 – 10:00 how to make a safe trip-identify the reasons why knowledge do not get used in practice-Hester Vermeulen, Nijmegen, The Netherlands

10:00 – 10:45 Learning from our mistakes- safe medication practiceClare Crowley, Oxford, United Kingdom


11:00 – 12:00 Profound knowledge of improvement- tools to improve the practice including examples of successful quality improvement Ann-Christine Andersson, Jönköping, Sweden

12:00 – 12:45 identify and overcome your own barriers “practice” Ann-Christine Andersson, Jönköping, Sweden & Anna Forberg, Lund, Sweden

12:45 – 12:50 closing

11:00 – 12:50 sessiOn 2Chairs: Antonia Cronin, London, United Kingdom; Emma Massey, Rotterdam, The Netherlands

11.00 – 11.30 Banking on living donors? the ethics of advanced living organ donation. Dominique Martin, Victoria, Australia

11.30 – 12.00 increasing opportunities for pre-emptive transplantation. David van Dellen, Manchester, United Kingdom

12.00 – 12.30 should organ sales be decriminalized?Sean Columb, Liverpool, United Kingdom

12:30 – 12:50 Q & a

09:00 – 12:50 YPt Workshop

about YPtThe Young Professionals in Transplantation (YPT) is the Network for Junior Transplant professionals of ESOT. It has been created to represent all young transplant clinicians and scientists who are beginning a career in transplantation and organ donation. YPT provides a forum for the junior professionals throughout Europe, working in the field of transplantation to discuss their needs and support their improvement. By creating a network based on a “younger perspective” we want to address our issues and facilitate the collaboration and friendship across inter-national bor-ders. We provide a platform for information, communication and ex-change between young transplant professionals who want to enhance their knowledge in transplantation and provide the opportunity to be actively involved in inter-national clinical and scientific exchange programs.GOaLs The group was designed to establish and maintain a network of young ESOT members under the age of 40 years, who want to become clinical and/or scientific experts in the field of transplantation. YPT is actively involved in the ESOT Biennial Meeting, organizing innovative sessions dedicated to junior professionals and arranging network-ing events to contact all young professionals and share their ideas.aims YPT wants to help young transplant professionals to enter the community of ESOT and therefore represents ESOT as a clinical, scientific and especially educational entity, which can help young professionals in their individual career development. We collaborate closely with the Education Committee in order to endorse high scientific and clinical standards for ev-ery YPT member. Together we promote educational programs and are actively involved in the organization of cutting-edge scientific sessions, carever development meetings and networking events on ESOT-associated congresses all over Europe through international collaboration with the national transplant societies.

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innOVatiOn WOrKshOPChair: Thomas Resch, Innsbruck, Austria

CrisismanagementEveryday transplant professionals deal with critical situations that arise. In this YPT session we will be learning from the best to understand how to deal with critical circumstances, drawing in on experience from diplomats, pilots, CEOs and surgeons.

09:00 – 09:20 crisis management. negotiating in times of crisisSir Stewart Eldon, Former United Kingdom Ambassador to NATO and Ireland, United Kingdom

09:20 – 09:30 discussionInterviewer Thomas Resch, Innsbruck, Austria

interVieW With...

09:30 – 09:45 the army captainCaptain Owen Davies, London, United Kingdom

09:45 – 10:00 the ceOAnnalisa Ponchia, Padova, Italy

10:00 – 10:15 the surgeonGeorgios Vrakas, Oxford, United Kingdom

10:15 – 10:30 Wrap up & take home message


10:40 – 11:40 shark tank session Chair: Zeeshan Akhtar, Oxford, United Kingdom; Sushma Shankar, Oxford, United KingdomSharks: Sir Stewart Eldon (Former Ambassador); John Piano (Transplant Connect); Annalisa Ponchia (former CEO ESOT)

Applicants: Start up invitations from #some campaigns

11:40 – 12:00 YPt activities

11:40 – 11:55 Winner of YPt fellowship: “my experience” - together with Mentor

11:55 – 12:05 “Get on the YPt-map!”


12:10 – 12:50 Board electionNewcomers briefly presenting themselves and their ideas Online voting via esOt app announcement & Photos

13:30 – 15:00 educatiOn tracK 1

Created by Luca Toti, rome, italy

immunOLOGY: aBcs and BeYOndChairs: Menna Clatworthy, Cambridge, United Kingdom; Anthony Warrens, London, United Kingdom

13:30 – 13:45 introduction by story teller & pre-assessment quizGiuseppe Tisone, Rome, Italy

13:45 – 14:05 Overview: hLa and immunologySebastiaan Heidt, Leiden, The Netherlands

14:05 – 14:25 the high immunological risk recipientChristophe legendre, Paris, France

14:25 – 14:45 the t and B cells in your transplant practiceCarla Baan, Rotterdam, The Netherlands

14:45 – 15:00 Post assessment quizGiuseppe Tisone, Rome, Italy

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Created by: Nicos kessaris, london, United Kingdom

it’s aLL aBOut saFetY - high performance, risk and safety lessons in transplantation

13:30 – 13:50 Building resilient systems in healthcare

13:50 – 14:10 threat and error management in surgeryNiall Downey, London, United Kingdom

14:10 – 14:30 human performance in crisis – a study in transplant surgeryPetrut Gogalniceanu, London, United Kingdom

14:30 – 15:00 mdt discussionAll involved

13:30 – 14:30 reFresher 1

The wonders of basic research: the clinical needs translational research the fastest and most efficient way from one to another.Created by: Henri leuvenink, Groningen, The Netherlands; Gavin Pettigrew, Cambridge, United Kingdom

transLatiOnaL scienceChairs: katja kotsch, Berlin, Germany; Gavin Pettigrew, Cambridge, United Kingdom

13:30 – 13:45 clinical models on warm perfusion and organ manipulationCyril Moers, Groningen, The Netherlands

13:45 – 14:00 Pre-clinical modelling of the alloimmune responseGiovanna lombardi, London, United Kingdom

14:00 – 14:15 Why bother about pre-clinical models?Carla Baan, Rotterdam, The Netherlands

14:15 – 14:30 Panel discussion

15:10 – 16:40 esOt & iPta JOint sessiOn

the cLinicaL reaLiZatiOn OF PrOGress in Pediatric transPLantatiOn

15:10 – 15:30 interspecies chimerism and Organ Generation; from miracle to reality

15:30 – 15:50 clinical realization of Organ reconditioning and repair

15:50 – 16:10 Liver splitting during machine Perfusion: fact or phantasy?

16:10 – 16:30 tolerance induction in Pediatric Organ transplantation: pros and cons

16:30 – 16:40 Q&a


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15:10 – 16:40 eutrain caLLinG: 1st stOP cOPenhaGen!

15:10 – 15:25 station master’s announcement: the eutrain consortiumCarmen lefaucheur, Paris, France

15:25 – 15:40 methodomicsOlivier Aubert, Paris, France

15:40 – 15:55 the future of biomarker guided patient care in solid organ transplantationOriol Bestard, Barcelona, Spain

15:55 – 16:10 molecular platform for precision diagnostics, data integration and analyticsAlexandre loupy, Paris, France

16:10 – 16:30 now get your boarding pass ready: how to catch the (eu-) train?yassine Bouatou, Paris, France

16:30 – 16:40 awardsCarmen lefaucheur & Alexandre loupy, Paris, France

15:10 -16:40 mdt 2 Created by: EDTCO, ECTTA, BSC

the Great ecmO chaLLenGe! (JOINT EDTCO/ECTTA/BSC)Chairs: Ivan knezevic, Ljubljana, Slovenia; David Paredes, Barcelona, Spain; Henri leuvenink, Groningen, The Netherlands

15:10 – 15:30 setting the scene

15:30 – 16:30 cLinicaL cases – Open discussion with audience with live voting (per-case discussion)

15:30 – 15:40 aV ecmO patient complicated with catastrophic cerebral damageArne Neyrinck, Leuven, Belgium

15:40 – 15:50 Discussion & Live Voting

15:50 – 16:00 nrP as organ rescue therapy in sudden irreversible ca in already diagnosed dBd


16:10 – 16:20 NRP after circulatory death declaration, as organ rescue therapy in already diagnosed DBD, in countries where Bd concept is not “well understood or accepted by relatives, as death concept”David Paredes, Barcelona, Spain


16:30 – 16:40 take home message via wordcloud

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antiBOdY mediated reJectiOn and cOmPLement. BrOthers in arms?Chairs: luuk Hilbrands, Nijmegen, The Netherlands; Henri leuvenink, Groningen, The Netherlands

15:10 – 15:25 role of non-hLa antibodies in antibody mediated rejectionDany Anglicheau, Paris, France

15:25 – 15:40 How does antibody binding induce graft injury?Olivier Thaunat, Lyon, France

15:40 – 15:55 tough-refractory amr: are we ready to throw the towel?David Taube, London, United Kingdom

15:55 – 16:10 management of ahus in kidney transplant patients: eculizumab for once and for all?Caroline Duineveld, Nijmegen, The Netherlands

16:10 – 16:25 next generation complement inhibitorsSøren Pischke, Oslo, Norway

16:25 – 16:40 Q&a

15:10 -16:40 cOrPOrate ParaLLeL sYmPOsia

17:00 – 19:00 PLenarY 1Created by: Finn Gustafsson, Copenhagen, Denmark; Allan Rasmussen, Copenhagen, Denmark

“Nothing in biology make sense except in the light of evolution” (Theodosius Dobzhansky)Why do we have diseases such as Parkinson’s disease, depression, and schizophrenia?If the concept “evolution” really works, these conditions should have been removed from our genes long times ago. Maybe the explanation is, that these genes constitute an advantage under other circumstances than those we have today. If this is so, we can find the explanation by studying DNA in ancient times. The study of evolution of diseases in this way may change our understanding of how, why, and when we get these kinds of diseases determined by our genes. Professor Eske Willerslev is one of the World’s leading DNA-scientists. Today we know a lot of diseases caused by our genetic constitution, and Eske Willerslev believes that this research will make us able to map most of the genomes leading to diseases.Having this knowledge, we will be able to take over the “responsibility” of the evolution. It will be possible to test embryos for the unwanted genomes and consequently offer abortion or via Crispr based technique to manipulate the genome. Therefore, we do not have to wait for the natural evolution to remove the genes causing disease when the advantages of having the genome vanished many generations ago.This, obviously, raises several ethical questions on which we must decide. When we have the knowledge about the genes causing disease, we cannot avoid decisions. To leave a person with a disease causing genome is also a decision. This may be a relatively easy decision if the genome causes a mild or a life-threatening disease. In between, it will be extremely difficult. And one thing is for sure, there will be enormous disagreement.Finally, an interesting thought in relation to organ transplantation. Most diseases leading to organ failure treated by transplantation are related to our genomic structure.

Be insPired, Be driVen: a neW PersPectiVe On the Future OF medicine.is OrGan transPLantatiOn GOinG tO Be Out OF Business?Chairs: Finn Gustafsson, Copenhagen, Denmark; Allan Rasmussen, Copenhagen, Denmark

17:00 – 17:10 Welcome by the congress chairs

17:10 – 17:40 KeYnOte LectureEske Willerslev, Copenhagen, Denmark


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17:40 – 18:00 about crisPr techniqueCord Herbert Brakebusch, Copenhagen, Denmark

18:00 – 18:20 ethical question? Rasmus Grønfeldt Winther, Santa Cruz, United States

18:20 – 19:00 honorary membership ceremony

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07:30 - 09:00 educatiOn tracK 2

Created by Luca Toti, rome, italy

tOLerance is here tO staYChairs: Menna Clatworthy, Cambridge, United Kingdom; Alberto Sanchez-Fueyo, London, United Kingdom

07:30 – 07:45 introduction by story teller & pre-assessment quizluca Toti, Rome, Italy

07:45 – 08:05 regulatory cells and toleranceDavid Berglund, Uppsala, Sweden

08:05 – 08:25 tolerance in kidney transplantationDavid Sachs, Boston, United States

08:25 – 08:45 tolerance in liver transplantationGiovanna lombardi, London, United Kingdom

08:45 – 09:00 Post assessment quizluca Toti, Rome, Italy

09:10 - 10:40 state OF the art 1Created by: Menna Clatworthy, Cambridge, United Kingdom; Gavin Pettigrew, Cambridge, United Kingdom

This is a high profile topic in biomedical research, as evidenced by the fact that many of the papers are published in the journals with the highest impact factors, Nature, Science, Cell etc.

micrOBiOme in transPLantatiOn: Friend Or FOe?

09:10 – 09:30 manipulating immunity with the microbiome Timor liwinski, Rehovot, Israel

09:30 – 10:00 the microbiome and immunotherapy Tomas Gajweski, Chicago, United States

10:00 – 10:20 the microbiome and rejectionSophie Brouard, Nantes, France

10:20 – 10:40 the urine microbiome and transplant toleranceMarisa Alegre, Chicago, United States

09:10 - 10:40 state OF the art 2Created by: Franz Immer, Zurich, Switzerland; David Rodriguez-Arias, Granada, Spain

Organ allocation is one of the key elements in-between organ donation and transplantation. As such, it takes place in a challenging framework. While it is guided by and must follow specific allocation prin-ciples, it often takes place in circumstances where time and/or information is limited, and it usually involves an interdisciplinary group of health care professionals. Additional factors that may influence the allocation process can include logistics, availability of resources, and organisational structures.

OrGan aLLOcatiOn aLGOrithm - heartless mathematics? how arithmetic impacts on organ allocationChairs: Franz Immer, Zurich, Switzerland; David Rodriguez-Arias, Granada, Spain

09:10 – 09:40 Very complicated math – reconfiguring organ allocation

09:40 – 10:00 ethical dilemmas in Liver transplant Organ allocation: is it time for a new mathematical modelAaron Ahearn, Los Angeles, United States

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11:10 - 12:40 insPire & driVe 1Created by: Constantino Fondevila, Barcelona, Spain; Vassilios Papalois, London, United Kingdom

Navigate transplant professionals as to how they can direct their efforts to advance their professional development and reach positions of responsibility leadership and esteem to shape the future of the world of transplantation.

hOW tO Get tO the tOPChairs: Constantino Fondevila, Barcelona, Spain; Vassilios Papalois, London, United Kingdom

11:10 - 11:30 are the values, principles and ethical standards of medical practice changing? a compass for the ambitious professionalsAnthony Warrens, London, United Kingdom

11:30 - 11:50 the healthcare landscape in transplantation and beyond in the 21st century; challenges and op-portunities for an ambitious generationElias Mossialos, London, United Kingdom

11:50 - 12:10 clinical achievement trough challenge and adversity; yes we can!Maria Siemionow, Chicago, United States

12:10 - 12:30 Career acceleration; wind behind the wings by Europe and European Organizations/ Scientific societiesRomuald krajewski, Warsaw, Poland

12:30 - 12:40 Q&a

09:10 - 10:40 state OF the art 3Created by: Henri leuvenink, Groningen, The Netherlands; Gavin Pettigrew, Cambridge, United Kingdom

Animal models have limitations, and as advances in our understanding of human transplant immunology con-tinue, these limitations become all the more apparent.Addressing the pertinent clinical research questions, such as the nature of the B cell response that underpins chronic rejection, is likely to need ever more specialized transplant models.

hOW tO chOOse the riGht research mOdeLChairs: Henri leuvenink, Groningen, The Netherlands, Nikke Norregard, Aarhus, Denmark

09:10 – 09:40 mouse modelsGavin Pettigrew, Cambridge, United Kingdom

09:40 – 10:00 Porcine models and what’s been achieved in the field of ex vivo normothermic perfusionMichael Nicholson, Leicester, United Kingdom

10:00 – 10:20 non-human primates: advantages and disadvantagesPer-Olof Berggren, Stockholm, Sweden

10:20 – 10:40 to be announcedZeeshan Ahktar, Oxford, United Kingdom

10:00 – 10:20 clinical impact of liver allocation algorithm on outcomeAxel Rahmel, Frankfurt, Germany


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11:10 - 12:40 reFresher 2Created by: Menna Clatworthy, Cambridge, United Kingdom; luuk Hilbrands, Nijmegen, The Netherlands

The pipeline of new immunosuppressive drugs is rather dry. Nevertheless in cancer / hematological malignancies and autoimmunity new drugs are introduced that may also find application in transplantation. A brand new field is immunometabolism.

LearninG FrOm neiGhBOurinG sPeciaLitiesChairs: Menna Clatworthy, Cambridge, United Kingdom; luuk Hilbrands, Nijmegen, The Netherlands

11:10 – 11:30 What is autoimmunity and autoinflammation in our patientsBent Winding Deleuran, Aarhus, Denmark

11:30 – 11:50 the potential of car t cell therapy Maeve O’Reilly, London, United Kingdom

11:50 – 12:10 immunometabolism

12:10 – 12:30 interactive discussion

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11:10 - 12:40 esOt LeOnardO da Vinci transPLant innOVatiOn research aWard

transPLant research chaLLenGe

11:10 - 11:15 editOr presents candidate 1

11:15 – 11:25 candidate 1

11:25 – 11:30 editOr presents candidate 2

11:30 – 11:40 candidate 2


11:45 – 11:55 candidate 3


12:00 – 12:10 candidate 4


12:15 – 12:25 candidate 5

12:25 – 12:30 Live voting & Jury result

12:30 – 12:40 acknowledgements on stage

13:00 - 14:00 Future Leaders On staGe

13:00 – 13:15 an experience in translational transplant immunologyMaria Meneghini, Barcelona, Spain

13:15 – 13:30 Enhancing the efficacy of T regulatory cells expressing a chimeric antigen receptor specific for MHC class i moleculesCaroline Dudreuilh, London, United Kingdom

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14:05 – 15:35 PLenarY 2Created by: Menna Clatworthy, Cambridge, United Kingdom; Gavin Pettigrew, Cambridge, United Kingdom

We currently use ‘omics’ technologies (proteomics, transcriptomics, genomics), in transplantation to identify biomarkers, signatures, or genetic variants associated with di erential outcomes. These technologies have been applied to bulk tissue or blood samples. Recent advances in genomics and informatics allow their application at the level of a single cell, using RNA sequencing and mass cytometry. These approaches are revolutionising our understanding of the cellular composition, origin and interactions within human organs and are being used to generate the first draft of the Human Cell Atlas (HCA) – an ambitious international e ort. The HCA will catalogue every cell and every cell state in the human body to deliver health-transforming insights into human biology. For example, single cell RNA sequencing has already allowed researchers to identify a previously unknown type of dendritic cell in peripheral blood.

sinGLe ceLLs Omics GeneratinG an atLas tO chart transPLant OrGansChairs: Menna Clatworthy, Cambridge, Country, TBA

14:05 – 14:25 using single cell technologies to generate a human cell atlasJohn Marioni, Cambridge, United Kingdom

14:25 – 14:45 spatial transcriptomics - Precision anatomical mapping of human organsMats Nilsson, Solna, Sweden

14:45 – 15:05 exploring the complexity of kidney transplant rejection using single cell technologiesBenjamin Humphreys, St. Louis, United States

15:05 – 15:25 human liver progenitors unveiled by single cell technologiesTamir Rashid, London, United Kingdom

15:25 – 15:35 Q&a

13:30 – 13:45 ex-vivo heart perfusion - clinical reality and future perspectives David Schibilsky, Freiburg, Germany

13:45 – 14:00 tBcFrancesca Tinti, Rome, Italy

16:00 - 17:00 insPire & driVe 2Created by: Franz Immer, Zurich, Switzerland; Vassilios Papalois, London, United Kingdom

The session aims to appraise to what extent evidence based practice is a driving force or a limitation for innovation and progress in the field of medicine and especially transplantation.

eVidence Based Practice is KiLLinG the art OF medicineChairs: Vassilios Papalois, London, United Kingdom; Stefan Schneeberger, Innsbruck, Austria

16:00 – 16:15 is modern medical practice an art or a science?Antony Warrens, London, United Kingdom

16:15 - 16:30 Learning from other professions: evidence and instincts in modern policingPeter Spindler, London, United Kingdom

16:30 - 16:45 triumphs and disasters in transplantation either evidence based and non-evidence basedThierry Berney, Geneva, Switzerland

16:45 – 17:00 Q&a

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17:00 - 18:00 reFresher 3Created by: Soren Sorensen Schwartz, Copenhagen, Denmark; Thomas Resch, Innsbruck, Austria

For health care professionals it is important to understand the possibilities and pitfalls in big data analysis in order to be able to direct this research area towards clinically relevant areas. In order to interact with professionals within big data analysis, i.e. within bioinformatics and related area of statistics, we need to have a more profound understanding of big data analysis than just looking at it as black box. We need to understand the various steps in big data analysis i.e data curation, data analysis modalities, data interpretation etc.

BiG data and BiOinFOrmatics in transPLantatiOn – neW tOOLs FOr transPLant research

17:00 – 17:20 can big data help predict post-transplant patient trajectory?Søren Brunak, Copenhagen, Denmark

17:20 – 17:40 Explainable artificial intelligence in health care – time to come out of the black box?lars kai Hansen, Copenhabgen, Denmark

17:40 – 18:00 Bioinformatic tools applied to characterize immune function – implication for transplantationMorten Nielsen, Copenhagen, Denmark

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Created by Luca Toti, rome, italyXenotransplantation is one among various alternatives to human organ donation. Offering several advantages, but still among main barriers are the strong immunological responses that human develop against animal antigens and zoonoses.

XenOtransPLantatiOn - sOOn a reaLitY?


16:15 – 16:35 immunologic barriers?Megan Sykes, New York, United States

16:35 – 16:55 infectious barrier?Jay Fishman, Boston, United States

16:55 – 17:15 regulatory barrier?linda Scobie, Glasgow, United Kingdom


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tuesdaY, sePtemBer 17


Created by Luca Toti, rome, italyClinical cutting edge education in organ perfusion: which organs, when, how, and why?

machine PerFusiOn GOes Prime timeChairs: Umberto Cillo, Padova, Italy; Constantino Fondevila, Barcelona, Spain

07:30 - 07:45 introduction by story teller & pre-assessment quizluca Toti, Rome, Italy

07:45 - 08:05 machine Perfusion in Liver transplantationIna Jochmas, Leuven, Belgium

08:05 - 08:25 machine Perfusion in Kidney and Pancreas transplantationkarim Hamaoui, London, United Kingdom

08:25 - 08:45 machine Perfusion in Lung transplantationJerome Jungschleger, Newcastle, United Kingdom


09:10 - 10:40 state OF the art 4

Created by: lorenzo Piemonti, Milan, Italy

No field in health sciences has more interest than organ transplantation in fostering progress in regenerative medi-cine because the future of no other field more than the future of organ transplantation will be forged by progress occurring in regenerative medicine. It is extremely rare for a single experiment to be so impactful and timely that it shapes and forecasts the experi-ments of the next decade. Here, we will adress how two such experiments—the generation of human induced plu-ripotent stem cells (iPSCs) and the development of CRISPR/Cas9 technology—have fundamentally reshaped our approach to biomedical research, stem cell biology, human genetics and potentially transplant medicine.

stem ceLLs and Gene editinG - Pluripotent stem cells meet genome editing: a disruptive wedding

09:10 – 09:40 Gene editing, Gene therapy, and cell Xenotransplantation: cell transplantation across species Pierre Gianello, Leuven, Belgium

09:40 – 10:00 ex vivo gene transfer and correction for cell-based therapiesluigi Naldini, Milan, Italy

10:00 – 10:20 iPs in humans: retinal regenerationMasayo Takahashi, Kyoto, Japan


09:10 - 10:40 state OF the art 5

Created by: Franz Immer, Zurich, Switzerland; David Rodriguez-Arias, Granada, Spain

How we reach our limits? Is there scope for expansion? How extended can be Extended Criteria? Is it for everybody?

dcd Push the BOundaries Chairs: Franz Immer, Zurich, Switzerland; David Rodriguez-Arias, Granada, Spain

09:10 – 09:40 european survey on dcd-practices in the member states of the cd-P-tOBeatriz Dominguez-Gil, Madrid, Spain

09:40 – 10:00 ethical issues in dcd-donationAnna dalle Ave, Lausanne, Switzerland

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11:10 - 12:40 insPire & driVe 3Created by: Ina Jochmans, Leuven, Belgium; Nicos kessaris, London, United Kingdom

What would you do if you had a history of depression, suicidal ideation or substance abuse? What would you do when ‘the light just goes out’ and you find yourself burned out?Learn first hand from a team of experts how mental health challenges can be recognised and overcome. Help us open the discussion on the importance of self-care and how we can break the stigma associated with mental health challenges such as burnout and depression in healthcare workers.

reLiGht mY FireChairs: Ina Jochmans, Leuven, Belgium; Nicos kessaris, London, United Kingdom

11:10 - 11:15 Why are we seeing burnout in transplant surgeons and how can we tackle it?Jan lerut, Brussels, Belgium

11:15 - 11:30 Psychological stress in transplant teams, what does the science tell us?Michelle Jesse, Detroit, United States

11:30 – 12:40 strengthening resilience and empowerment at workElke Geraerts, Antwerp, Belgium

11:10 - 12:40 reFresher 4

inFLammatiOn

11:10 – 11:30 Inflammation, frailty and morbidity in relation to organ transplantation – how to evaluate and what is the connectionHelle Bruunsgaard, Copenhagen, Denmark

09:10 - 10:25 state OF the art 6Created by: Nicos kessaris, London, United Kingdom

Paediatric transplantation can be very challenging and is not performed in many countries. Promote discussions in collaboration with our international partners to shape a new Era.

smaLL Patients, BiG chaLLenGesChair: Nicos kessaris, London, United Kingdom

09:10 – 09:25 Paediatric transplant recipients in the 21st centuryJelena Stojanovic, London, United Kingdom

09:25 - 09:40 immunosuppression challenges in paediatric transplantationStephen Marks, London, United Kingdom

09:40 - 09:55 Kidney transplantation in children with vascular complicationsMarco Spada, Rome, Italy

09:55 - 10:10 Liver transplantation in complex paediatric recipientsUmberto Cillo, Padova, Italy

10:10 - 10:25 cardiothoracic transplantation in complex paediatric recipientsAnne Dipchand, Toronto, Canada

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10:00 – 10:20 Impact of procurement modalities and machine perfusion techniques on prediction of graft function and outcomePhilipp Dutkovski, Zurich, Switzerland


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14:05 – 15:35 PLenarY 3Created by: Ina Jochmans, Leuven, Belgium; Henri leuvenink, Groningen, The Netherlands

Perfect organ preservation – a cornerstone of transplantation – might sound like a dream ... yet, the last years have seen tremendous progress. Technology has caught up with our creative minds and we are now able to preserve organs in dynamic and more physiological conditions than static cold storage ever could. Organ perfusion is here to stay, paving the path towards perfect organ preservation and opening doors to organ reconditioning, treatment, modification, management and more. Be inspired and motivated by the most creative thinkers in the organ preservation arena and discover what they dream of.

PerFect OrGan PreserVatiOn and recOnditiOninG – an eLusiVe dream?Chairs: Ina Jochmans, Leuven, Belgium; Henri leuvenink, Groningen, The Netherlands

14:05 – 14:15 meet modern preservation strategies: media introduction

14:15 – 14:55 tOP dOG deBatePeter Friend, Oxford, United Kingdom Stefan Berger, Groningen, The Netherlands Constantino Fondevila, Barcelona, SpainChristina Falk, Hannover, GermanyJohn Dark, Newcastle, United Kingdom

15:05 – 15:25 Grand chaLLenGes rOund

15:25 – 15:35 criticaL cOmmentatOrsRutger Ploeg, Oxford, United KingdomAmelia Hessheimer, Barcelona, Spain

16:00 – 17:00 insPire & driVe 4Created by: Erik Berglund, Stockholm, Sweden; Andreas Zuckermann, Vienna, Austria

This session will highlight the most promising engineering progress in the field of artificial organs.

enGineerinG the Future

16:00 – 16:20 Bioartificial Liver : what next ?Cecile legallais

16:20 – 16:40 (Bio)artificial kidney: opportunities and challenges for achieving better blood detoxificationDimitrios Stamatialis

16:40 – 17:00 Artificial heart

16:00 - 17:00 mdt 3 Created by: Constantino Fondevila, Barcelona, Spain; Gavin Pettigrew, Cambridge, United Kingdom

Challenging the boundaries and exploring the limits of our abilities and ambitions. Based on expert experience debates and challenging cases. End up in trials and disasters.

the unthinKaBLe dOnOr/reciPientChair: Constantino Fondevila, Barcelona, Spain

11:30 – 11:50 Inflammation and antibody mediated rejection – the missing link?Caner Susal, Heidelberg, Germany

11:50 – 12:20 Anti-inflammatory and cardiovascular risk reduction - what are the treatment optionsAlan Jardine, Glasgow, United Kingdom

12:20 – 12:40 Q&a

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16:00 – 17:30 educatiOn tracK 5

Created by luca Toti, Rome, Italy

New strategies to avoid the injury: is there still a place for them?

ischemia rePerFusiOn inJurY – stiLL?


16:15 – 16:35 how cell death in regulated in transplantationAndreas linkermann, Dresden, Germany

16:35 – 16:55 the Organ repair center: Bringing Organ Preservation to the next LevelGiuseppe Orlando, WinstonSalem, United States

16:55 – 17:15 approaches to prevent iri experimentally and clinicallyAnthony Warrens, London, United Kingdom



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Created by Luca Toti, rome, italyWhat changed in the last 60 years, how far we can go? Will it replace transplantation?

reGeneratiVe transPLantatiOnChairs: Pierre Gianello, Brussels, Belgium; Giuseppe Orlando, WinstonSalem, United States

07:30 - 07:45 introduction by story teller & pre-assessment quizluca Toti, Rome, Italy

07:45 - 08:05 stem cell therapy: state of the artGraziella Pellegrini, Modena, Italy

08:05 - 08:25 Artificial oesophagi in children with major malformations of the oesophagusPaolo De Coppi, London, United Kingdom

08:25 - 08:45 Bioengineering a Human Face GraftBenoit lengele, Leuven, Belgium


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09:10 - 10:40 state OF the art 7Created by: luuk Hilbrands, Nijmegen, The Netherlands

Adequate dosing of immunosuppressive drugs is key to the success of organ transplantation. During recent years new insight have been acquired concerning the effects of pharmocogenetic variations on the disposition of com-monly used drugs. However, it remains a challenge to demonstrate the clinical relevance of pharmacogenetic testing for transplant patients. A unique situation in organ transplantation is the co-existence of the genotype of the donor and that of the recipient, both potentially affecting the pharmacokinetics and pharmacodynamics of a drug. Moreover, transplant patients frequently use multiple drugs besides their immunosuppressives. The pre-emptive genotyping of a panel of established clinically relevant pharmacogenomic markers holds promise for a next step in precision medicine.

PharmacO GenOmics

09:10 – 09:30 is knowledge of the cYP3a4 and cYP3a5 genotype useful in tacrolimus treated patients?Teun van Gelder, Rotterdam, The Netherlands

09:30 – 09:50 Which genotype is relevant: recipient or donor?Dirk kuypers, Leuven, Belgium

09:50 – 10:10 Pharmacogenomics of triazole antifungal agents – translation into clinical practicekelly E. Caudle, Memphis, United States

10:10 – 10:30 Pre-emptive pharmacogenetic testing to reduce adverse drug reactions – a next step?Henk-Jan Guchelaar, Leiden, The Netherlands

10:30 – 10:40 Q&a

09:10 - 10:40 state OF the art 8Created by: Soren Sorensen Schwartz, Copenhagen, Denmark

Traditional PET, CT, MR and ultrasound imaging have been used in relation to organ transplantation for years. How-ever, new exciting development both in relation to tracers, in relation to analysis of data and development within the technique has occurred during recent years. Potentially it can be possible to image the immune response and the metabolic processes in transplanted organs in real time but also to dig our hidden information from traditional images. Also 3D ultrasound imaging combined with contrast may revail new information on transplanted organs. Although largely untested in relation to transplantation, these new techniques could prove of great value in relation to organ transplantation in clinic as well as in research.

neW imaGinG techniQues

09:10 – 09:40 immune imaging in transplantation – a game changer?Andeas kjær, Copenhagen, Denmark

09:40 – 10:00 radiomics – there is more in a picture than meets the eye Philippe lambin, Maastricht, The Netherlands

10:00 – 10:20 hyperpolarized magnetic resonance imaging – Potentials and pitfallsChristopher laustsen, Aarhus, Denmark

10:20 – 10:40 3d ultrasound – ready for daily clinical use in organ transplantation? Ben Stenberg, Newcastle, United Kingdom

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Created by: luuk Hilbrands, Nijmegen, The Netherlands; Finn Gustafsson, Copenhagen, Denmark

Traditional outcome measures in organ transplantation include patient survival, graft survival, and graft function. Growing attention for the patient’s perspective of health and disease has led to the development of patient-re-ported measures which can be classified into two different categories: patient-reported outcomes (PROs), usually referring to health-related quality of life, and patient-reported experiences (PREs), referring to perception of the care that was received. Tools to measure PROs and PREs are labeled PROMs and PREMs. While there is a rapid expansion of the reporting of patient-reported outcomes in various medical areas, the use in organ transplantation is strikingly limited. This session focuses on the current status of PREMs and PROMs in organ transplantation: a premise or still a prom-ise? In addition to measuring patient- reported outcomes after transplantation, it is relevant to know what patients actually expect from a transplantation. Importantly, for successful design and implementation of patient-reported outcomes in patient management and clinical research the participation of patients is an absolute prerequisite.

transPLant success: the Patient’s deFinitiOn

09:10 – 09:30 how to include patient reported outcome measures in clinical trialsAndrew Bottomley, Brussels, Belgium

09:30 – 09:50 development and use of PrOms in patients with chronic kidney disease and kidney transplantationFriedo Dekker, Leiden, The Netherlands

09:50 – 10:10 What do patients expect from a transplant?Allison Tong, Sydney, Australia

10:10 – 10:30 How to define a successful transplantation: the patient’s perspectiveHenning Søndergaard, Copenhagen, Denmark

10:30 – 10:40 Q&a

11:10 – 13:00 PLenarY 4Created by: Erik Berglund, Stockholm, Sweden; Vassilios Papalois, London, United Kingdom; lorenzo Piemonti, Milan, Italy; Thomas Resch, Innsbruck, Austria; Andreas Zuckermann, Vienna, Austria

The session aims to critically appraise all the indications in modern practice that we are moving into a more holistic approach when dealing with end stage organ failure including modalities beyond transplantation.Clear signals FROM ESOT2019 Congress in Copenhagen that the direction of travel is changing. Clear signals BEYOND ESOT2019 Congress in Copenhagen that the direction of travel is changing. How our practice for treating organ failure will look like at the ESOT Congress of 2039?

deaLinG With OrGan FaiLure: a chanGe in the directiOn OF traVeL? have your sayChairs: Vassilios Papalois, London, United Kingdom; Stefan Schneeberger, Innsbruck, Austria

11:10 – 11:30 clear signals FrOm esOt2019 that the direction of travel is changingIna Jochmans, Leuven, Belgium

11:30 – 11:50 clear signals BeYOnd esOt2019 that the direction of travel is changingMenna Clatworthy, Cambridge, United Kingdom

11:50 – 12:10 Moderated panel discussion:how our practice for treating organ failure will look like at the esOt congress of 2039?

12:10 – 12:40 it’s Your time

12:40 – 13:00 the way forward: the future is Great, the Future is esOt!Vassilios Papalois, London, United Kingdom


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SHAPING THE FUTUREIN TRANSPLANTS

*Certican_Trasplants_Campaign_ENG_2.indd 1 29/4/19 12:30

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EsoTin collaboration with

sChool oF mEdICINE, sTaNFoRd uNIVERsITy

TuRNING REsEaRCh INTo aN aGENT oF ChaNGE

This satellite meeting will take place at stanford, university california. Delegates in Copenhagen and others do not need to travel to Stanford.

the session will be live broadcasted from the esOt transplant Live show.

tuesdaY, sePtemBer 17, 201918:35 – 20:20

local time in Copenhagen09:35 – 11:20

local time in Stanford

ESOT

From ideas to startup to clinical products to patients: a roadmap. common milestones from birth to growth and success.

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EsoT 2019 CoNGREss aWaRds

esOt Young investigator awardAwards will be assigned to 10 young clinicians or scientists (under 35 years of age), who have submitted the ten best abstracts to the ESOT 2019 Copehagen Congress. The award will be given to the first author/presenter on the basis of the quality of the contribution to donation or transplantation and the best abstract score.

Awards amount to € 1.500 each.

esOt Leonardo da Vinci transplant research innovation awardSupported by Ten outstanding contributions are selected from all submitted abstracts by the Scientific Program Committee, based on the overall referees’ score. The award will be presented during the ‘Transplant Research Challenge’ session on Monday, September 16 from 11:10 to 12:40. During this session, the audience together with a jury of top journal edi-tors selects the winner and two runners-up.

Awards amount to € 10.000 for the winner and 2 awards of € 2.500 for the runners-up..

strongertogether awardThe award will be assigned to the Transplant Centre submitting between 5 and 10 abstracts.The Award is assigned by the Scientific Program Committee of the ESOT2019 Congress and notified by email at the same time of the Abstract notification.Awards recognition will be honoured during the presentation Session.

Award amounts to € 2.500.

strongertogether pro awardThe award will be assigned to the Transplant Centre submitting between 5 and 10 abstracts with the best score among all abstract submitted from single centres.The Award is assigned by the Scientific Program Committee of the ESOT2019 Congress and notified by email at the same time of the Abstract notification.Awards recognition will be honoured during the presentation Session.

Award amounts to € 5.000.

TuRNING REsEaRCh INTo aN aGENT oF ChaNGE

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EsoT 2019 CoNGREss REGIsTRaTIoN FEEs

type of registration regular registrationUntil 01 September

Late & Onsite From 02 September

esOt member € 670 € 700

easyesOt* € 770 € 800

non-member € 940 € 970

members qualifying for a reduced fee ** € 370 € 400

easyesOt reduced ** € 420 € 450

Fees are VAT exempt.* easy esOt includes: the lowest registration fee for the ESOT Congress (i.e. the reduced fee for ESOT members) ∙ Your ESOT membership fee for the current year (including full benefits).** reduced fee (available for esOt members only): trainees, nurses, transplant coordinators, allied health professional/participants from low/middle income countries (According to World Bank List: http://data.worldbank.org/country) ∙ Local hospital staff members OR Members of the Danish Transplant Society.

registration for the esOt2019 congress in copenhagen is open online.

registration includes:¢Admission to all scientific sessions¢Admission to all Specialty Update Symposia¢Access to the exhibition¢Access to delegate lounges¢Participant’s kit with Congress material¢Admission to poster opening & networking reception¢Refreshment breaks

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CoPENhaGEN

THE CREATIVE CAPITAL Meet Copenhagen, the cultural capital of the NorthWith an abundance of world-renowned museums, music venues, festivals and historical sites, Copenhagen is full of character. And among the picturesque cobbled squares, canals and copper spires, the city boasts the best shopping, restaurants and nightlife in Northern Europe.Copenhagen is often labelled the ‘world’s most livable city’, the title supported with many key reasons. Among them were safety, tolerance, green initiatives, international connectivity, creative environments, relaxed lifestyle, democratic design and the active use of city spaces to name just a few.From marauding Vikings and the world’s oldest monarchy to philosophical pioneers and the iconic Little Mermaid – Copenhagen is the image of a modern-day fairy tale.Danish design is internationally recognized for its clean lines, advanced manufacturing processes and use of quality materials – resulting in timeless products, buildings and civic spaces found in the city.Copenhagen is home to the recent boom in New Nordic cuisine and has earned itself a unique reputation as a gastronomic capital. The city offers an impressive choice of a constantly evolving Copenhagen’s food and the restaurant scene caters to all budgets and tastes.Copenhagen truly is a green city – with climate-friendly citizens to match. In fact, Copenhagen has excellent public transport and one of the world’s most dedicated cycling cultures. In line with this, we are committed to make ESOT2019 a sustainable event.ESOT is proud and honoured to feature a brand new logo for the ESOT2019 Congress in Copenhagen designed by the famous Danish designer and artist Per arnoldi.

VENUEBella Center Copenhagen is located centrally in the new part of Copenhagen, Ørestad, and also the neighborhood around is developing rapidly into a modern and active part of Copenhagen. Bella Center Copenhagen is just 6 kilometers away from Copenhagen Airport and 8 kilometers away from Copenhagen city centre. Bella Center Copenhagen is also surrounded by Fields, Scandinavia’s largest shopping centre, Royal Golf Center and protected natural areas that are ideal for a jog.Bella center copenhagen - Center Boulevard 5 - DK - 2300 Copenhagen

HOTEL ACCOMMODATIONCAP Partner has been appointed as the official booking agent for the ESOT 2019 in Copenhagen and will be happy to assist you with your bedroom reservation (group bookings as well as individuals).Our hotel selection includes a wide range of hotels and we hope you will be able to choose the most suitable accommodation for you.In case your enquiry is more specific, please do not hesitate to contact us and we will be happy to look for best alternative for you.hotel accommodation for individual clients (up to 5 bedrooms)Please click on this link to see full list of hotels that can be reserved:https://www.esotcongress.org/hotel-accommodation/

COPENHAGEN TRAVEL PASSThe Copenhagen Travel Pass offers congress participants unlimited transportation by bus, train and Metro in the Greater

Copenhagen area (zones 1-99) for 36,00 kr. a day, including upon arrival at Copenhagen Airport. This is 72% cheaper than regular day tickets for public transport in Copenhagen.Order your Travel Pass and have the ticket sent directly to your e-mail and/or your mobile phone as a text message. Check on https://www.esotcongress.org/copenhagen-travel-pass/

AIR TRAVELDiscounted travel is available to with two airline groups AIR FRANCE-KLM and Lufthansa. Check on https://www.esotcongress.org/air-travel/

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Bella Center Copenhagen is located centrally in the new part of Copenhagen, Ørestad, and also the neighborhood around is developing rapidly into a modern and active part of Copenhagen. Bella Center Copenhagen is just 6 kilometers away from Copenhagen Airport and 8 kilometers away from Copenhagen city centre. Bella Center

Copenhagen is also surrounded by Fields, Scandinavia’s largest shopping centre, Royal Golf Center and protected natural areas that are ideal for a jog.

ESOT GOLD CIRCLE

ESOT EDUCATION CIRCLE

ESOT SILVER CIRCLE

ESOT2019 SUPPORTERS

EsoT CoRPoRaTE suPPoRTERs

ESOT gratefully acknowledges the support of our Corporate Partners, Congress Supporters and Exhibitors.

ESOT2019 EXHIBITORS

atara Biotherapeutics ❚ Biotest ❚ Bridge to Life ❚ china Organ harvest

research center ❚ csL Behring ❚ dr. Franz Köhler chemie ❚ donation

& transplantation institute ❚ e3 cortex ❚ eBers medical technology ❚

Fresenius medical care ❚ Glycorex transplantation ❚ hansa Biopharma ❚ iGL

❚ immudex ❚ mallinckrodt Pharmaceuticals ❚ natera ❚ neovii ❚ One Lambda

❚ OrganOx ❚ Organ assist ❚ Organ recovery systems ❚ QuOd ❚ saLF ❚

the transplantation society ❚ ViroGates ❚ Wisepress.com

RECREATE PMS(FROM PDF)

RECREATE PMS(FROM PDF)

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ESOT OFFICE Ph +39 049 8597652 ¡ Mob +39 346 1779104

E: [email protected] ¡ W: www.esotcongress.org ¡ T/F: @ESOTtransplant ¡ #ESOT2019

visit www.esotcongress.org

#ESOT2019 Advanced Programme · 2019-07-31 · — #ESOT2019 — 3 Dear Colleagues, Dear Friends,...

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Transcript of #ESOT2019 Advanced Programme · 2019-07-31 · — #ESOT2019 — 3 Dear Colleagues, Dear Friends,...