QURAT KHAN, M.D. Epilepsy, Stroke. BRIEF OVERVIEW TLE Epilepsy.
Epilepsy
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Transcript of Epilepsy
DEFINITION:
When nerve cells in the brain fire electrical impulses at a rate of up to four times
higher than normal, this causes a sort of electrical storm in the brain, known as a seizure. A
pattern of repeated seizures is referred to as epilepsy.
Epilepsy is a group of related disorders in the brain's electrical systems that are
characterized by a tendency to cause recurrent seizures. Seizures cause changes in movement,
behavior, sensation, or awareness, including loss of consciousness or convulsions, which last
from a few seconds to a few minutes in most individuals.
SYMPTOMS:
Generalized seizures
Seizures that appear to involve all areas of the brain are called generalized seizures. Six types
of generalized seizures exist.
Absence seizures. Absence seizures, previously known as petit mal seizures, often
occur in children and are characterized by staring into space or subtle body
movements such as eye blinking or lip smacking. These seizures may occur in clusters
and cause a brief loss of awareness.
STARING EYE BLINKING LIP SMACKING LOSS OF
INTO SPACE AWARENESS
Tonic seizures. Tonic seizures cause stiffening of your muscles. These seizures
usually affect muscles in your back, arms and legs and may cause you to fall to the
ground.
STIFENING OF MUSCLES FALL DOWN
Atonic seizures. Atonic seizures, also known as drop seizures, cause a loss of muscle
control, which may cause you to suddenly collapse or fall down.
LOSS OF MUSCLE CONTROL FALL DOWN
Clonic seizures. Clonic seizures are associated with repeated or rhythmic, jerking
muscle movements. These seizures usually affect the neck, face and arms.
JERKING MUSCLE MOVEMENTS
Myoclonic seizures. Myoclonic seizures usually appear as sudden brief jerks or
twitches of your arms and legs.
JERKS OF ARM TWITCHING OF LEG
Tonic-clonic seizures.
are the most dramatic
type of epileptic
seizure and can cause an abrupt loss of consciousness, body stiffening and shaking,
and sometimes loss of bladder control or biting your tongue.
LOSS OF CONCIOUSNESS BODY STIFFENING &
BITING TOUNGUE
SHAKING
Partial seizures
Partial seizures involve just one side of the brain. Partial seizures
may be classified as simple or complex.
Simple partial seizures usually involve a single part of the brain such as the
motor area and sensory area.
Motor area- These cause a change in muscle activity. For example, a person may have
abnormal movements such as jerking of a finger or stiffening of part of the body.
JERKING OF HAND JERKING OF FINGER
Sensory area- People with sensory seizures may smell or taste things that aren't there;
hear clicking, ringing, or a person's voice when there is no actual sound; or feel a
sensation of "pins and needles" or numbness.
SENSE OF SMELL SENSE OF HEARING
SENSATION OF PINS AND NEEDLES NUMBNESS
Psychological area- Memory or emotional disturbances.
MEMORY DISTURBANCE EMOTIONAL DISTURBANCE
Complex partial seizures occur in the frontal or temporal lobe with the brain
and often involve other areas of the brain that affect alertness and awareness. These
seizures result in daydream like states and sometimes involve unusual activities like
picking at the air as if something was there, repeating words or phrases, laughing, or
other activities.
DAY DREAMING UNUSUAL LAUGHING
CAUSES:
Sleep deprivation – overtired, not sleeping well, not getting enough sleep
At times of fevers or other illnesses
Flashing bright lights or patterns
Alcohol or drug use.
Stress
Associated with menstrual cycle (women) or other hormonal changes
Not eating well, low blood sugar
Specific foods, excess caffeine or other products that may aggravate seizures
Use of certain medications
Head trauma.
Infectious diseases
Genetic influence.
Electrolyte abnormalities.
Prenatal injury. Developmental disorders.
LIFESTYLE MODIFICATIONS FOR EPILEPSY:
The best preventive measure is to comply strictly with the drug regimen as prescribed.
Seizures and epilepsy cannot be prevented by lifestyle changes alone, but people can
make behavioural changes that improve their lives and give them a sense of control.
FIRST AID FOR EPILEPSY
Do’s and Dont’s
AVOIDING EPILEPTIC TRIGGERS
In most cases, there is no known cause for epilepsy, specific events or conditions may
trigger them and they should be avoided.
Inadequate or Fragmented Sleep Alcohol and
Smoking
Flashing Lights Head trauma
Stress
RELAXATION TECHNIQUES
Deep breathing Biofeedback
Meditation techniques
EXERCISE
Exercise is important for many
aspects of epilepsy, although it can
be problematic.
Weight bearing exercise helps
maintain bone density.
Exercise can also help to prevent
weight gain.
There have been some reports that
exercise may trigger seizures in
some patients, but this is
uncommon.
DIETARY MEASURES
Many nutrients and have been implicated
in the treatment of epilepsy, however, only the Ketogenic and Modified
Ketogenic Diets have been medically proven to effectively treat epilepsy.
Nutritionally balanced diet with adequate fluid intake
a. Balancing macronutrients (fat, carbohydrate, protein)
b. Eating a wide variety of foods to maximize micronutrient
intake
Maintain a healthy weight by consuming the appropriate amount
of calories, fat, protein and carbohydrate.
Balance calorie intake with energy output.
Cut back on portion sizes.
Make half your plate vegetables.
Choose low fat dairy like skimmed milk, etc.
Cut back on foods with solid fats and added salt.
Drink water and avoid sugar and sweetened beverages.
Control your food: eat at home more often, eat lean protein.
THE KETOGENIC DIET
The Ketogenic diet, which is very high in fat (90%), very low in carbohydrates,
and low in protein, has been studied and debated for decades. It has proven to be
helpful for many children with severe epilepsy that does not respond to AEDs. It is
not clear why it works.
The standard theory is that burning fat instead of carbohydrates causes an increase
in ketones (chemical substances in the body that result from the breakdown of fat
in the body). When excessive levels of ketones are produced, a metabolic state
called ketosis happens.
Ketosis appears to alter certain amino acids in the brain and to increase levels of
the neurotransmitter gamma aminobutyric acid (GABA), which helps prevent
nerve cells from over firing.
Side Effects and Complications:
To prevent serious side effects, children need regular monitoring by a doctor, especially
when the diet is first initiated. Side effects or complications that may occur at the start of
the diet include:
Acidosis, a build-up of acid in the blood and body
Low blood sugar (hypoglycaemia)
Stomach upset
Dehydration
Lethargy
Side effects that may occur later on include:
Unhealthy cholesterol and lipid levels
Kidney stones, which may be a complication of acidosis, occur in about 5% of
children on the diet. Patients should drink plenty of fluids. Oral potassium citrate
may be protective.
Slowing of growth
Decreased bone density
EMOTIONAL AND PSYCHOLOGIC SUPPORT
Some of the following tips may help the patients with epilepsy:
Often patient can be given the hope that they will outgrow the disorder.
Most of patients will not have seizures triggered by sports or by any other ordinary
activities that are enjoyable and healthy.
The patients should be active participants in maintaining their drug regimens,
which should be presented in as positive a light as possible.