March 18, 2011

Energy/Climate Sustainability Program

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Our Global Corporation

● >10,000 employees worldwide

● Helping patients in 100 countries

● 8 manufacturing sites

● 20 major marketed products

● 2010 revenue of $4.05 billion

● ~70 locations in >40 countries

● Henri Termeer: Chairman, CEO

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Global Energy Sustainability Program: Overview

Demand

Greenhouse Gases

Supply Market Intelligence Strategic Sourcing Leverage Scale

Competitive Energy Pricing

Eliminate Waste Benchmark Metrics

Measure Carbon Footprint Engage Employees

Reduction in:• Energy

Consumption• Operating cost

• Achieve Target• Environmental

Leader

Mission:To partner with sites to procure and use energy at Genzyme in an efficient, cost effective, and environmentally responsible way

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Sustainable Buildings

● 9 certified green buildings– LEED– French HQE– UK Carbon Trust

● 8 additional green buildings ‘in the pipeline’– LEED– China Star

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Deep Energy Efficiency Improvements for Buildings

● Global Energy Assessment Program

– Comprehensive energy audits at 5 major sites

– 200+ energy conservation opportunities

– Median payback under 2 years

– Reduction of at least 3,000 MTCO2e

– Goal: annual audits

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Deep Energy Efficiency Improvements for Buildings

● NSTAR Rebates: Memorandum of Understanding (Massachusetts)

– Genzyme: Commitment to annual minimum investment in energy efficiency

– NSTAR: Corresponding minimum annual investment (97 cents per dollar)

– Up to 6,450 MTCO2e reduction

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Deep Energy Efficiency Improvements for Buildings

● Genzyme Center: Ongoing Commissioning (OCx) Project– 14 opportunities identified – Actual energy cost reduction of 24% HVAC (16% total) – Potential energy cost reduction 38% HVAC (25% total)– Potential reduction of 1,207 MTCO2

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Deep Energy Efficiency Improvements for Buildings

● Deadband Project

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Electricity (Energy) Supply

● DOER Alternative Portfolio Standard (APS)– APS requires a certain percentage of the state’s electric load to

be met by eligible highly efficient technologies such as CHP– Allows Genzyme to monetize the energy efficiency of Allston

Combined Heat & Power (CHP) plant

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Electricity (Energy) Supply

● Green Power– Strategy: purchase 100% green power for all certified green buildings – Approximately 15% of Genzyme global electricity is third party verified

green power (RECs)– 2010: purchased over 65,000 MWH green power– Waterford, Ireland: 46,727 MWH yielding reduction of 27,423 MTCO2e

at zero price premium

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Transportation

● Massachusetts Rideshare Program– Framingham: 150 carpool or transit (7%)– Cambridge: 375 carpool, transit or walk/bike (47%) – Strategies:

• Web based ride matching• Subsidized transit passes• Guaranteed ride home• Preferred parking• Bicycle incentives• Zip Car • Genzyme Shuttle Busses

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Transportation

● Scope 3 Business Travel: 20,000 MTCO2e reduction

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Green Communities

● Volunteer weatherization and energy efficiency “barn-raising”– Demonstrates strong employee connection to local communities– Support from Cambridge HEET http://heetma.com – Genzyme G.I.V.E. eligible

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Non-Energy Emissions

● 2010 Solid Waste Recycling Statistics (global)– Total Solid Waste: 5,517 ton– Recycled Solid Waste: 2,235 ton– Recycling Ratio: 41%

● LEED Recycled Construction and Demolition Debris– Allston MA: 969 tons (97%)– Ridgefield NJ: 1,182 tons (91%)

● 2009: Wastewise Partner of the Year, Large Business

● 2010: Wastewise Honorable Mention, Large Business

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“Cross Cutting” Initiatives

● EDF Climate Corps Fellow– MBA students with a passion for energy and

the environment– 10-12 week fellowship– “We train tomorrow's business leaders to

incorporate energy efficiency as a standard management practice.”

– Funding support from A Better City (ABC)

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Overall Progress

March 18, 2011

Energy/Climate Sustainability Program