ENDOMETRIOSIS 2003
Transcript of ENDOMETRIOSIS 2003
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MOHAMMED KASHIFGROUP:6YEAR:4
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Endometriosis is a condition where tissuesimilar to the lining of the uterus (theendometrial stroma and glands, which should
only be located inside the uterus) is foundelsewhere in the body.Example : - Ovaries,bladder, fallopian tubes
Lesions may occur at distant sites: pleural
cavity, liver, kidney, gluteal muscles, bladder,etc . 10% of all women during their reproductive
years are affected by endometriosis .
Affects an estimated 176 million womenworldwide re ardless of their ethnic and social
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Illustration of the organs inside awoman's abdomen, showing siteswhere endometriosis can develop.Possible sites are shown in blue.From top: abdominal wall,intestines, fallopian tubes, ovary,appendix, uterus, peritoneum,
cervix, rectum, bladder, vulva.
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The exact cause of endometriosis remainsunknown, many theories have been presentedto better understand and explain its
development. Estrogens Retrograde menstruation Mllerianosis
Coelomic Metaplasia Genetics Transplantation Immune system
Environment Birth Defect
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Endometriosis lesions react to hormonalstimulation and may "bleed" at the time ofmenstruation. The blood accumulates
locally, causes swelling, and triggersinflammatory responses with the activationof cytokines. It is thought that this processmay cause pain.
Pain can also occurfrom adhesions (internal scar tissue)binding internal organs to each other,causing organ dislocation. Fallopian tubes,ovaries, the uterus, the bowels, and the
bladder can be bound together in ways that
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Pelvic pain(acute or chronic) Infertility
DysmenorrheaDyspareuniaDysuria
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Constipation chronic fatigue heavy or long uncontrollable menstrual periods with
small or large blood clots gastrointestinal problems including diarrhea, bloating
and painful defecation extreme pain in legs and thighs pain from adhesions which may bind an ovary to the
side of the pelvic wall, or they may extend betweenthe bladder and the bowel,uterus, etc.
extreme pain with or without the presence of menses premenstrual spotting mild to severe fever headaches depression hypoglycemia (low blood sugar) anxiety
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Endoscopic image ofendometriotic lesions at
the peritoneum of thepelvic wall.
A small adhesion on anovary about to be removed
surgically
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Severe endometriosis on theback of the uterus causingadhesions of the bowel andpelvic organs
Endometriosis growingon the ovary andfallopian tube
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Complications of endometriosisinclude:
Internal scarringAdhesionsPelvic cystsChocolate cyst of ovariesRuptured cystBowel obstruction
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Pelvic exam.Ultrasound
MRILaparoscopy
http://images.google.com/imgres?imgurl=http://www.emedicine.com/radio/images/2277ultrasound.jpg&imgrefurl=http://www.emedicine.com/radio/topic250.htm&h=200&w=200&sz=10&hl=en&start=1&tbnid=lKBrQGzOiToZFM:&tbnh=104&tbnw=104&prev=/images?q=endometrioma&svnum=10&hl=en&lr=&sa=G -
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Procedures are classified as conservative when reproductive organs
are retained -Cystectomy semi-conservative when ovarian function
is allowed to continue, and
radical when the uterus and ovaries areremoved Hysterectomy, Bilateralsalpingo-oophorectomy
Laparoscopy
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Use of fertility medication thatstimulates ovulation (clomiphene
citrate, gonadotropins) combinedwith intrauterine insemination (IUI)enhances fertility in the patients.
In-vitro fertilization (IVF) proceduresare effective in improving fertility inmany women with endometriosis
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Men can also develop endometriosisafter prolonged treatments involvingsynthetic estrogen
Reported cases in primates such asbaboons, African Green Monkeys, andRhesus Monkeys
Pharmaceutical companies cashing inon womens pain= 3 monthEndometriosis Kit $525.95 USD
Endometriosis has been removed fromareas other than the abdomen such asthe thigh, thumb, and knee
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This is a disease without a cure butwith the proper communication, a
woman with endometriosis canattempt to live a normal, functioninglife. Using cystectomy and ablativesurgery, pregnancy rates areapproximately 40%
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