Endocrineexxx

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    Endocrine

    Glands

    Hormone

    Secreted

    Chemical

    GroupTarget Tissue Action/Response

    Hypothalamus

    (Produced by

    Hypothalamus,

    released from posterior

    Pituitary)

    OxytocinPeptide

    Uterus,

    Mammary glands

    Stimulates Uterine muscle contraction,

    release of milk by mammary glands

    AntidiureticHormone Peptide Kidneys Stimulates water reabsorption by kidneys

    Hypotalamic!releasing and

    inibiting ormonesPeptide Anterior Pituitary "egulate anterior pituitary ormones

    Pituitary Gland

    PosteriorAntidiuretic

    Hormone Peptide Kidneys

    #onser$es water

    #onstricts %lood $essels

    Oxytocin Peptide

    Uterus,

    Mammary glands

    increases uterine contractions

    &ncrease milk letdown from mammary glan

    Anterior'yroid!stimulating

    ormone('SH)

    *lycoprotein 'yroid gland

    &ncrease 'yroid ormonesecretion

    ('yroxine and 'riiodotyronine)

    +uteiniing Hormone(+H)

    or interstitial cell!stimulating

    ormone (SH)

    *lycoprotein

    O$ary,

    'estis

    Promotes o$ulation andprogesterone production in o$ary-

    Promotes testosterone syntesis and suppfor sperm cell production in testis

    .ollicle!stimulatingormone

    (.SH)*lycoprotein

    .ollicles in o$aryin females,

    Seminiferoustubules in males

    Promotes follicle maturation and estrogensecretion

    Promotes sperm cell production in testis

    Adrenocorticotropicormone(A#'H)

    Peptide Adrenal #ortex

    &ncreases secretion of glucocorticoidormones

    (#ortisol!increases skin pigmentation of iconcentrations)

    Melanocyte!stimulating

    ormone (MSH)Peptide

    Melanocytes inskin

    &ncreases melanin production in melanocytto make te skin darker in color

    *rowt Hormone Protein

    Soft tissues,

    bones

    &ncreases gene expression, lipid breakdowand release of fatty acids from cells

    &ncreases blood glucose le$elsMammary glands, Stimulates milk production and prolongs

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    Nicole Nibshian Dela Rosa Seat #:15

    Section: 2G-PHARMACY

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    Endocrine

    Glands

    Hormone

    Secreted

    Chemical

    Group Target Tissue Action/Response

    Thyroid Gland

    'yroidHormones

    &odinatedAmino acid

    All tissues

    &ncrease metabolic rates,

    /ssential for normal process of growt anmaturation

    #alcitonin Peptide%ones, Kidneys,

    &ntestine

    0ecreases rate of bone breakdown,

    Pre$ents large increase in blood #a12 le$efollowing a meal

    Parathyroid

    Gland

    ParatyroidHormone

    Peptide %ones, Kidneys,

    &ncreases rate of bone breakdown byOsteoclasts,

    &ncreases 3itamin 0 Syntesis,

    /ssential for maintenance of normal bloodcalcium le$els

    Pancreas

    Insulin Protein

    Especially Liver,

    Skeletal muscle,

    Adipose tissue

    Increases uptake and use of glucose and

    amino acids

    Glucagon Protein Primary Liver

    Increases breakdown of glycogen

    Release of glucose into the circulatory syst

    Adrenal Glands

    Adrenal Medulla

    Epinephrine

    some

    Norepinephrine

    Modified

    Amino acid

    Heart, Blood vessels,

    liver, fat cells

    Increases cardiac output,

    Increases blood flow to skeletal muscles an

    heart,

    Increases release of glucose and fatty acid

    into blood,

    (prepares body for physical activity)

    Adrenal Cortex

    Mineralcorticoids

    (aldosterone)Steroid

    Kidneys; to lesser

    degree,

    Intestine and Sweat

    glands

    Increase rate of sodium transport into bod

    Increase rate of potassium excretion,

    Secondarily favor water retention

    Glucocorticoids

    (cortisol)Steroid

    Most tissues

    (e.g. liver, fat,

    skeletal m., immune,

    tissues

    Increase fat and protein breakdown,

    Increase glucose synthesis from amino acid

    Increase blood nutrient levels,

    Inhibit inflammation and immune respons

    Endocrine

    Glands

    Hormone

    Secreted

    Chemical

    Group

    Target Tissue Action/Response

    Reproductive

    Organs/Gonads

    Testes Testosterone Steroid Gonads, Skin

    muscle, bones

    (most tissues)

    Aids in sperm cell production,

    maintenance of functional reproductive

    organs,

    secondary sexual characteristics and sexu

    behaviour

    Ovaries Estrogens

    Progesterone

    Steroid Gonads, Skin

    muscle, bones

    (most tissues)

    Aid in uterine and mammary gland

    development and function, external genital

    structure, secondary sexual characteristics

    sexual behaviour, menstrual cycle

    Uterus, Ovaries,Inflammed tissues

    Prostaglandins Steroid Most tissues Mediate Inflammatory responses,

    Increase Uterine contractions and ovulatio

    Pineal Gland Melatonin Modified

    Amino acid

    Brain (hypothalamus) Inhibits secretion of gonadotropin-releasin

    hormone (inhibiting reproduction)

    Thymus Thymosin Peptide Immune tissues

    T Lymphocytes

    Promotes immune system development an

    function

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