Encapsulation Technologies - Lambson Ltd€¦ · Encapsulation material Gelatine + Gum Arabic...
Transcript of Encapsulation Technologies - Lambson Ltd€¦ · Encapsulation material Gelatine + Gum Arabic...
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Leading the way
Encapsulation Technologies
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Leading the wayWhat is Microencapsulation?Lambson Microencapsulation Technologies
• Size: typically 1µm- 1mm
• Active ingredients are entrapped in a shell or matrix
• This renders them temporarily inactive
• Release of the active is “triggered” by a stimulus
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Leading the wayWhy Encapsulate?
Isolate, Protect and Stabilise
Controlled Release
Appearance
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Leading the wayIsolate, Protect and Stabilise
• Prevents degradation
• Flavour and odour masking
• Separates reactive components
• Manipulation of encapsulate (Oil & water)
• “Plug and play” add to formulation without changing it
• Flavour /Fragrance burst or slow over time release
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Leading the wayControlled Release
Microcapsule
Active
Shear
pH
Temperature
Other
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Leading the wayAppearance
Visual cues
Aesthetic appeal
Colour changes
Premier branding
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Personal & Home Care
Consumer Markets
Food, Beverages & Nutrition
• Shampoo and Shower gels
• Cosmetic Creams
• Hand Sanitisers
• Deodorants
• Toothpaste
• Detergent & Fabric conditioner
• Targeted release
• Self-healing actives
Pharma & Medicine
• Vitamins, minerals, amino acids & unsaturated fatty acids
• Animal & Plant extracts, Flavours & Fragrances
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Leading the wayIndustrial Markets
Construction & coatings Agriculture & Environment
• Pesticides & repellents
• Fertilisers
• Paints, antimicrobials & protection coatings
• Self-healing actives
• Phase changing materials
• Breakage markers
• Inkjet pigment
• Thermochromic dyes Invo-Caps containing Concrete healing active[1]
[1] A Kanellopoulos et al 2017 Smart Mater. Struct. 26 04502
Capsule wall
Encapsulated healing
active
Crack Healed concrete
Illustration of self-healing concrete
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Leading the waySelecting the right technology
Consider:
• Core Material• Physical state, size, hydrophobicity• Concentration of active
• Wall material• Market: Consumer or industrial• Application: Isolate, protect, stabilise• Regulatory: grade, FDA, etc.• Release mechanism
• Process• Stability of core material• Particle size and distribution• feasibility
SEM image of Vida-Caps
Light Micrograph of Vida-Caps
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Leading the wayInvo-CapCore/Shell Matrix
TechnologyComplex
CoacervationSpray Chilling
Material encapsulatedOils, some aqueous
activesAqueous, oils
Encapsulation material
Gelatine + Gum Arabic Lipids/ waxes, gelatine
% loading of active 90% 40%
Trigger mechanism Pressure, DigestionPressure,
Temperature,Digestion
Particle size 5-1500µm 10-1000µm
Biodegradability
Vegan
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Leading the wayInvo-CapCore/Shell Matrix
TechnologyComplex
CoacervationIn situ polymerisation Spray Chilling
Hydrogel matrix beads
Material encapsulatedOils, some aqueous
activesOils, some aqueous
activesAqueous, oils
Large water soluble molecules, oils
Encapsulation material
Gelatine + Gum ArabicMelamine
Formaldehyde, Urea Formaldehyde
Lipids/ waxes, gelatine Alginate, agar
% loading of active 90% 90% 40% 15%
Trigger mechanism Pressure, Digestion PressurePressure,
Temperature,Digestion
Pressure, Diffusionequilibrium
Particle size 5-1500µm 0.1-300µm 10-1000µm 200-4000µm
Biodegradability
Vegan
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Leading the wayVida-Caps
TechnologyComplex Coacervation
GelatineComplex Coacervation
Gelatine – free (Vida-Caps)
Material encapsulated
Oils, some aqueous actives Oils, some aqueous actives
Encapsulation material
Gelatine + Gum Arabic Chitosan + Gum Arabic
% loading of active 90% 90%
Trigger mechanism Pressure, Digestion Pressure
Particle size5-1500µm 20-1500µm
Hydro-alcoholicstability
Vegan
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Leading the way
20– 1500µmHydro-
alcoholic Stability
Why Choose Vida-Caps?
Encapsulates hydrophobic
materials
High Loading (90%)
Bio-degradable
Vegan
Plastic Free
Pressure release
Bespoke Design
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Leading the wayConclusion
Lambson are proud to offer a wide range of encapsulation products, customised to suit your requirements, and created to help take your formulations and developments to the next level.
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With offices and facilities in England, Europe, China, Japan and America we offer a truly Global Supply Network.
Thank you for your attentionAny Questions?