emqs-obs

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EMQs in Obstetrics

Transcript of emqs-obs

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EMQs in Obstetrics

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Normal pregnancy

Theme: Physiological changes in

pregnancy

Options:

A Increase in plasma fibrinogenB Reduction of renal threshold for glucoseC Rise in cardiac outputD Increase in red cell massE Increase in creatinine clearanceF Increase in plasma volumeG Delayed gastric emptyingH Inhibition of gonadotrophin secretionI Decrease in peripheral vascular resistanceJ Venous compression by enlarging uterus

Lead-in:

For each of the following case scenarios, please select the relevantphysiological mechanism from the option list. Each option may beused once, more than once or not at all.

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�Q1 A 30-year-old G3 P2 presents for a routine ante-natal clinicvisit at 22 weeks’ gestation. She is very well and the preg-nancy has been progressing in a satisfactory fashion. Herlast recorded pre-pregnancy blood pressure was 138/85mmHg. Today her BP is 88/50 mmHg.

�Q2 A 23-year-old G1 P0 has a routine FBC taken at 36 weeks’gestation. This reveals an Hb of 10.0 g/dl (11.5–16.5), anMCV of 81 fl (80–90) and an MCH of 28 pg (27–32).

�Q3 A 31-year-old G2 P1 presents for a routine ante-natal clinicvisit at 32 weeks’ gestation. Her blood pressure is 110/76mmHg and the urinalysis reveals no protein, no nitrites and+ of glucose.

�Q4 A 22-year-old primigravida is admitted to the labour wardat 41 weeks’ gestation in advanced labour; her cervix is6 cm dilated and the fetal membranes are absent on vaginalexamination. The fetal heart rate is satisfactory. She isgiven oral ranitidine by her attending midwife.

�Q5 A 27-year-old primigravida at 36 weeks’ gestation attendsthe ante-natal clinic for a routine appointment. She com-plains of vulval discomfort and on examination vulvalvaricosities are apparent.

Theme: Pregnancy milestones

Options:

A 20–22 weeksB 9 weeksC 6 weeksD 16 weeksE 34 weeksF 12 weeks

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G 3 days post-partumH 42 weeksI 36–38 weeksJ 12 hours post-partum

Lead-in:

For each of the following case scenarios, please select the mostlikely time of onset from the option list. Each option may be usedonce, more than once or not at all.

�Q6 A 33-year-old G3 P2, who has had two spontaneous vaginaldeliveries at term previously, attends for routine ante-natalcare in her third pregnancy. She has just started feeling fetalmovements.

�Q7 A 23-year-old woman in her first pregnancy has undergonean emergency Caesarean section for delay in the first stageat 42 weeks’ gestation. The baby was born in good con-dition. She is now feeling low, tired and tearful.

�Q8 A 29-year-old G2 P1 with an uncomplicated singletonpregnancy attends a routine ante-natal clinic appointment.Her symphysio-fundal height has been satisfactory so far.On examination today, the uterine fundus is palpable at thexiphisternum for the first time.

�Q9 A 38-year-old woman in her first pregnancy attends forroutine ante-natal care. For the first time in this pregnancy,the midwife describes the presenting part as engaged.

�Q10 A 27-year-old G5 P3 with a viable singleton pregnancyattends for routine ante-natal care. The uterine fundus ispalpable at the umbilicus.

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Ante-natal care andpre-natal diagnosis

Theme: Ante-natal screening and

diagnosis

Options:

A AmniocentesisB Nuchal translucency screeningC Chorionic villous samplingD CordocentesisE Fetal cardiac echoF Pre-implantation diagnosisG Sex selectionH Second trimester triple testI Serum AFPJ Uterine artery Doppler

Lead-in:

For each of the case scenarios below, select the most useful ante-natal test from the option list. Each option may be used once, morethan once or not at all.

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�Q11 A 42-year-old G1 P0 seeks your advice about ante-natalscreening and diagnosis. She is currently nine weeks preg-nant. She would like to know whether or not her baby hasDown’s syndrome, and would like a test at the earliestpossible opportunity.

�Q12 A 24-year-old woman with a 10-year history of IDDMpresents for a booking visit at 22 weeks’ gestation in herfirst pregnancy. Her HbA1c is found to be 10.1%.

�Q13 A 33-year-old G1 P0 attends for her booking visit at 11weeks’ gestation. She wishes to know the risk of her babyhaving Down’s syndrome at the earliest possible stage.

�Q14 A 25-year-old G2 P1 attends for an ante-natal visit at 22weeks’ gestation. In her previous pregnancy she developedsevere pre-eclampsia and intrauterine growth restriction,and had to be delivered by Caesarean section at 29 weeks’gestation.

�Q15 A 29-year-old woman presents for ante-natal counsellingat 15 weeks’ gestation. Her sister had a baby with Down’ssyndrome, and she would like to know whether or not herbaby is affected.

Theme: Aneuploidy and genetic

disorders

Options:

A Edwards’ syndromeB Turner’s syndromeC AchondroplasiaD Cystic fibrosisE Fragile X syndromeF Klinefelter’s syndrome

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G Turner mosaicH Down’s syndromeI TriploidyJ Congenital adrenal hyperplasia

Lead-in:

For each of the case scenarios below, select the most likely diag-nosis from the option list. Each option may be used once, more thanonce or not at all.

�Q16 A 42-year-old G1 P0 declines the second-trimester Down’sserum screening test, but attends for a detailed ultrasoundscan at 21 weeks’ gestation. On ultrasound the baby issmall, hasbilateral choroid plexus cysts and a ‘rocker bottom’appearance of both feet.

�Q17 A 24-year-old G2 P1 has a booking for ultrasound scan at11 weeks’ gestation, which reveals a cystic hygroma. Shedeclines further testing and on subsequent scans the hygromaappears to resolve; she delivers a live female infant at 38weeks’ gestation. The baby has a webbed neck and bilateralpedal oedema.

�Q18 A 39-year-old G4 P3 undergoes nuchal translucencyscreening at 11 weeks’ gestation. This reveals an increasednuchal translucency, but the patient decides against invasivetesting. At 21 weeks she undergoes a detailed ultrasoundscan, which suggests the presence of a ventricular septumdefect, a short femur, a thick nuchal fold and a sandal gap.

�Q19 A 25-year-old G2 P1 undergoes a detailed ultrasound scanat 19 weeks’ gestation. This reveals a significantly smallbaby and a disproportionately large placenta. The patientfeels unwell during the scan and a midwife is called to seeher. She finds her blood pressure to be 165/100 mmHg andthere is +++ of proteinuria on urinalysis.

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�Q20 A 33-year-old G1 P0, who books late, undergoes anultrasound scan at 28 weeks’ gestation. This reveals a fetalhead and abdominal circumference on the 50th centile, butall four limbs are below the 3rd centile. The sonographeralso notes ‘frontal bossing’. On further enquiry, the patientdenies a history of musculoskeletal disorders in her or herpartner’s family.

Theme: Ante-natal risk assessment

Options:

A Fetal growth restrictionB Intrauterine fetal deathC MacrosomiaD Pulmonary hypoplasiaE Trisomy 21F Congenital heart defectG Neural tube defectH Placenta percretaI Pre-eclampsiaJ Post-maturity

Lead-in:

For each of the case scenarios below, select the most likely risk tothe pregnancy from the option list. Each option may be used once,more than once or not at all.

�Q21 A 29-year-old G5 P4, who has had four previous Caesareansections, falls pregnant following contraceptive failure.The detailed fetal ultrasound at 22 weeks’ gestation reportsnormal fetal anatomy and an anterior placenta whichreaches the cervical os but does not cover it.

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�Q22 A 37-year-old G1 P0 of Indo-Asian origin attends the ante-natal clinic at 35 weeks’ gestation. She has no complaints,but you note from her hand-held record that her urinalysishas revealed glycosuria for the past three ante-natal visits.

�Q23 A 43-year-old woman is admitted to the labour ward withregular uterine tightenings, now occurring every threeminutes. She is currently 27 weeks pregnant. She had anamniocentesis at 20 weeks’ gestation because of soft markersfor aneuploidy on her detailed anomaly ultrasound scan.The fetal karyotype was normal, but she reports that shehas had a copious watery vaginal discharge since theamniocentesis.

�Q24 A 22-year-old woman books for ante-natal care at 19 weeks’gestation in her first pregnancy. She has epilepsy, and herseizures are controlled on sodium valproate 600 mg b.d.

�Q25 A 29-year-old G1 P0 attends the ante-natal clinic at 33weeks’ gestation, having had generalised pruritus for thepast three weeks. It is becoming increasingly distressingand she has not been able to sleep properly for severalnights. Her midwife took a number of blood tests two daysago and the serum bile acids are raised.

Theme: Teratogens

Options:

A LamotrigineB WarfarinC Ionising radiationD RubellaE PhenytoinF CytomegalovirusG Varicella

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H TetracyclineI Vitamin AJ Alcohol

Lead-in:

For each of the case scenarios below, select the teratogen mostlikely to be responsible from the option list. Each option may beused once, more than once or not at all.

�Q26 A 26-year-old G1 P0 with a prosthetic mitral valve deliversa live male infant at 38 weeks’ gestation. The child issubsequently found to have chondrodysplasia punctata.

�Q27 A 31-year-old G3 P2 with epilepsy and gingival hyper-plasia, who has not sought any ante-natal care, delivers alive female infant at approximately 34–35 weeks’ ges-tation. The newborn has a cleft lip and palate, and acongenital heart defect.

�Q28 A 31-year-old G2 P1 with spider naevi, palmar erythemaand deranged liver function tests delivers a female infant at33 weeks’ gestation. The baby’s birth weight is below the3rd centile, and there is marked microcephaly and mid-facehypoplasia. The child is subsequently found to have mod-erate mental retardation.

�Q29 A 19-year-old G2 P0 with a history of chlamydial PIDdelivers an appropriately grown baby at 41 weeks’ ges-tation. In subsequent months, the child’s teeth are noted tobe of yellow-brown colour.

�Q30 A 29-year-old G1 P0 delivers a live male infant at full term.Her pregnancy was uncomplicated apart from mild flu-likesymptoms at 8–10 weeks’ gestation. The baby has bilateralcataracts, sensorineural deafness, a cardiac malformationand microcephaly.

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Commonpresentations inpregnancy

Theme: Early pregnancy

Options:

A Threatened miscarriageB Ectopic pregnancyC Retained products of conceptionD Ruptured luteal cystE Urinary tract infectionF Complete miscarriageG AppendicitisH Incomplete miscarriageI Molar pregnancyJ Missed miscarriage

Lead-in:

For each of the case scenarios below, select the most likely diag-nosis from the option list. Each option may be used once, more thanonce or not at all.

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�Q31 A 30-year-old woman in her fourth pregnancy attends fora routine ante-natal clinic visit at 16 weeks’ gestation. Shehas had vague lower abdominal discomfort, but no bleed-ing per vaginam. She mentions that her nausea, breasttenderness and urinary frequency have now completelyresolved. On examination her uterus is not palpable abovethe symphysis pubis.

�Q32 A 41-year-old P2 is 14 weeks pregnant by dates. Herperiods were regular prior to pregnancy (5/35). She hashad recurrent hospital admissions with excessive vomitingin this pregnancy, but has not yet had a dating ultrasoundscan. At today’s booking visit she is still complaining ofvomiting, and the midwife finds the uterus to be large fordates on palpation.

�Q33 A 44-year-old G2 P0 calls out her midwife at 15 weeks’gestation. She reports a 24-hour history of spotting pervaginam, and is very anxious. She denies pain. The midwifefinds her uterus palpable above the symphysis pubis and thefetal heart is audible with a SonicAid.

�Q34 A 39-year-old G3 P0 is admitted to the gynaecology wardat eight weeks’ gestation. She reports a five-day history ofspotting per vaginam. Over the past six hours she experi-enced increased bleeding with passage of clots and severecramping pain. After passing a particularly large clot intothe toilet, the symptoms of pain and bleeding appear tohave resolved completely, but the patient is still anxious.On pelvic examination the uterus is of normal size and thecervical os is closed.

�Q35 A 22-year-old G1 P0 calls her midwife complaining of lowerabdominal pain and vaginal bleeding. She underwent medicalevacuation of the uterus three days ago because of a ‘blightedovum’ at eight weeks’ gestation. Since the intervention thebleedinghasbeengettingprogressivelyheavierandassociatedwith intermittent cramping lower abdominal pain.

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Theme: Abdominal pain 1

Options:

A Urinary tract infectionB Placental abruptionC Red degeneration of fibroidD Musculoskeletal painE AppendicitisF PyelonephritisG Symphysis pubis dysfunctionH Pre-term labourI Ovarian cyst torsionJ Gastroenteritis

Lead-in:

For each of the following cases, please select the most likelydiagnosis from the option list. Each option may be used once,more than once or not at all.

�Q36 A 25-year-old primigravida at 26 weeks’ gestation is ad-mitted to the labour ward with a one-day history of inter-mittent, sharp left iliac fossa (LIF) pain, associated withnausea. On examination there is marked tenderness in theLIF and features of peritonism. Her pulse is 100 bpm, BP is122/67 mmHg and temperature is 37.0 8C. Urinalysis isnegative.

�Q37 A 37-year-old G3 P2 of Afro-Caribbean origin presents tothe labour ward at 32 weeks’ gestation with severe constantleft-sided abdominal pain. This is a singleton pregnancy.On examination the symphysio-fundal height is 36 cm. Heruterus is soft but irregular, and there is marked tendernessover the right side of the uterus. Maternal pulse is 114 bpm,BP is 119/62 mmHg and temperature is 36.9 8C. The fetalheart is 146 bpm. Urinalysis is negative.

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�Q38 A 30-year-old primigravida at 28 weeks’ gestation is ad-mitted to the labour ward with a three-day history ofabdominal pain and backache. The pain is worse on move-ment. She is currently in the process of decorating thenursery. On examination her uterus is soft, and there ismild generalised abdominal tenderness. Maternal pulse is88 bpm, BP is 132/75 mmHg and temperature is 37.0 8C.The fetal heart is 142 bpm. Urinalysis is negative.

�Q39 A 17-year-old primigravida with a twin pregnancy at20 weeks’ gestation is admitted to the labour ward with a24-hour history of worsening, right-sided, constant abdom-inal pain associated with nausea and anorexia. On exam-ination her uterus is soft, but there is marked tendernesswith rebound to the right of the umbilicus. Maternal pulseis 110 bpm, BP is 100/58 mmHg and temperature is 37.68C. The fetal heart rates are 168 and 159 bpm, respectively.Urinalysis is clear.

�Q40 A41-year-oldprimigravidaat31weeks’ gestation is admittedto the labour ward with a six-hour history of intermittentabdominal pain and backache, which appears to increasein severity every 10 minutes. On examination the presen-tation is cephalic and the head is engaged. Maternal pulse is100 bpm, BP is 122/67 mmHg and temperature is 37.2 8C;the fetal heart is 137 bpm. Urinalysis reveals + of protein.

Theme: Abdominal pain 2

Options:

A FBCB Urine cultureC Blood culturesD Abdominal X-rayE Pelvic ultrasound scan

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F MRIG CTH LFTI Upper GI endoscopyJ Serum bile acids

Lead-in:

For each of the following cases, please select the most usefulinvestigation from the option list. Each option may be used once,more than once or not at all.

�Q41 A25-year-oldprimigravidaat18weeks’ gestation is admittedto the labour ward with a one-day history of intermittent,sharp left iliac fossa (LIF) pain, associated with nausea.On examination there is marked tenderness in the LIFand features of peritonism. Her pulse is 100 bpm, BP is122/67 mmHg and temperature is 37.2 8C. Urinalysis isnegative.

�Q42 A 41-year-old G3 P2 of African origin presents to thelabour ward at 24 weeks’ gestation with severe, constant,left-sided abdominal pain. On examination the symphysio-fundal height is 28 cm. Her uterus is soft but irregular, andthere is marked tenderness over the right side of the uterus.Her pulse is 114 bpm, BP is 119/62 mmHg and temperatureis 36.9 8C. The fetal heart rate is 146 bpm. Urinalysis isnegative.

�Q43 A 38-year-old primigravida at 28 weeks’ gestation is ad-mitted to the labour ward with a three-day history ofworsening upper abdominal pain associated with nauseaand vomiting. On examination her uterus is soft, and thereis marked tenderness in the right upper quadrant of theabdomen. Maternal pulse is 108 bpm, BP is 112/75 mmHgand her temperature is 37.5 8C. The fetal heart rate is142 bpm. Urinalysis is negative.

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�Q44 A 17-year-old primigravida is admitted to the labour wardat 26 weeks’ gestation with a 24-hour history of worsening,right-sided, constant abdominal pain associated with nauseaand anorexia. On examination her uterus is soft, but thereis marked tenderness with rebound to the right of theumbilicus. Maternal pulse is 110 bpm, BP is 100/58 mmHgand her temperature is 37.6 8C. The fetal heart rate is159 bpm. Urinalysis is negative.

�Q45 A 41-year-old primigravida at 28 weeks’ gestation is ad-mitted to the labour ward with a 12-hour history of inter-mittent abdominal pain and backache, which appears toincrease in severity every 20 minutes. On examination thepresentation is cephalic and the presenting part is free.The uterus is soft but irritable. Her pulse is 100 bpm, BP is122/67 mmHg and temperature is 37.1 8C; the fetal heartrate is 137 bpm. Urinalysis reveals + of protein and ++ ofleucocytes.

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Theme: Anaemia

Options:

Lead-in:

For each patient described below, please select the most likely fullblood count result from the options above. Each option can be usedonce, more than once or not at all.

�Q46 A 41-year-old G8 P5 presents for booking at approx-imately 29 weeks’ gestation. She has a longstanding historyof alcohol abuse and poor social circumstances.

�Q47 A 29-year-old primigravida is admitted from the ante-natalclinic at 30 weeks’ gestation with a BP of 165/105 mmHg.She is complaining of nausea and vomiting, and of rightupper quadrant discomfort. Her urinalysis reveals ++++ ofproteinuria and + of blood.

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Hb (g/dl)11.5–16.5

Haemat-ocrit (%)37–47

MCV (fl)80–90

MCH(pg)27–32

WCC(�109/l)4–11

Platelets(�109/l)150–400

A 10.5 35 90 29 9 190

B 8.9 30 79 22 8.7 220

C 12.1 38 85 30 10 399

D 15.3 50 82 30 11 370

E 9.9 35 101 34 6 189

F 13.1 39 85 29 7.6 133

G 8.1 30 80 27 12.8 69

H 13.8 37 82 28 8.8 151

I 11.9 50 90 32 6.6 755

J 11.0 37 89 31 15.8 620

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�Q48 A 19-year-old primigravida of Indo-Asian origin presentsfor booking in at the ante-natal clinic. She has recentlyarrived in the country, and is thought to be approximately11 weekspregnant.You are takingahistoryviaan interpreter.When asked about family history, the patient discloses thatone of her siblings died in childhood from severe anaemia.

�Q49 A 30-year-old G3 P2, who has had hyperemesis gravidarumin both her previous pregnancies, is admitted at sevenweeks’ gestation to the gynaecology ward with excessivevomiting. She has not been able to tolerate any solids orfluids for the past week. Urinalysis reveals +++ of ketones.

�Q50 A 36-year-old woman delivers spontaneously at 33 weeks’gestation, having had pre-labour pre-term rupture of mem-branes from 29 weeks’ gestation. She is re-admitted to thepost-natal ward one week post-partum five days later withlower abdominal pain. On examination her temperatureis 38.9 8C, pulse is 128 bpm and her uterine fundus ispalpable at the level of the umbilicus and tender.

Theme: Shortness of breath

Options:

A Pulmonary oedemaB PneumoniaC Pulmonary embolismD Hyperventilation syndromeE Physiological effect of pregnancyF PneumothoraxG AnaemiaH Heart failureI Pleural effusionJ Asthma

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Lead-in:

For each patient described below, please select the most likelyunderlying cause from the above option list. Each option can beused once, more than once or not at all.

�Q51 A 41-year-old G8 P6, who is currently 16 weeks pregnant,is admitted to A&E with acute breathlessness followinga lengthy car journey. Her BMI is 38 and she smokes fivecigarettes per day. She has no known medical problems.Her O2 saturation in room air is 93%, pulse is 96 bpm, BP is102/67 mmHg and her respiratory rate is 28 bpm. Onauscultation her chest is clear, with normal air entry bilat-erally.

�Q52 A 19-year-old nullipara with a BMI of 25 is admitted to thelabour ward at 20 weeks’ gestation complaining of chesttightness and breathlessness over the past two hours. Shehas no known medical problems apart from hay fever. Onexamination she appears dyspnoeic at rest and is usingaccessory muscles. Her O2 saturation in room air is 95%,pulse is 122 bpm, and her BP is 102/67 mmHg. On aus-cultation there is widespread wheezing over both lungs.

�Q53 A 28-year-old primigravida with a BMI of 27 is admitted tothe labour ward at 36 weeks’ gestation complaining ofoccasional shortness of breath, fatigue, palpitations, dizzi-ness and headaches. She has had symptoms for four weeksbut only mentioned them to her midwife today. She lookspale, BP is 124/76 mmHg, her pulse is 104 bpm and her O2

saturation in room air is 98%. Her chest is clear onauscultation.

�Q54 A 17-year-old GI PO, who is a known substance misuser, isadmitted to hospital at 28 weeks’ gestation with chest painand breathlessness. On examination her BP is 100/66 mmHg,pulse is 104 bpm and O2 saturation in room air is 95%. Onchest auscultation she has right basal crepitations and thereis bronchial breathing.

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�Q55 A 35-year-old GI PO is brought in by ambulance to thelabour ward because of difficulty breathing for the past twohours. She is currently 24 weeks pregnant. She denies chestpain, but complains of dizziness and tingling in both hands;her symptoms started after she received some bad newsabout a member of her family. On examination her BPis 110/82 mmHg, pulse is 100 bpm and her O2 saturation inroom air is 98%. On auscultation her chest is clear.

Theme: Reduced fetal movements

Options:

A PolyhydramniosB Maternal anxietyC Fetal dyskinesia syndromeD Anterior placentaE Fetal growth restrictionF Placental abruptionG Talipes equinovarusH Obstetric cholestasisI Drug effectJ Vasa praevia

Lead-in:

For each patient described below, please select the most likely causefor reduced fetal movements from the above option list. Eachoption can be used once, more than once or not at all.

�Q56 A 41-year-old G6 P0, who is currently 18 weeks pregnant,is admitted to hospital having not felt the baby move for thepast four hours. Her BP is 128/64 mmHg, pulse is 88 bpm,and urinalysis is negative. Her uterus is soft, non-tender,equivalent to dates in terms of size, and the fetal heart isheard with a SonicAid at 165 bpm.

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�Q57 A 25-year-old G3 P2 is admitted to the labour ward with a10-day history of reduced fetal movements. She is currently32 weeks pregnant, and her dating and detailed ultrasoundscans were entirely normal. On examination her uterus istense but non-tender, and her symphysio-fundal heightis 37 cm. Her BP is 110/65 mmHg, pulse is 92 bpm andurinalysis reveals +++ of glucose. A CTG is performed andis found to be normal.

�Q58 A 28-year-old primigravida is admitted to the labour wardat 34 weeks’ gestation with reduced fetal movements for24 hours. On examination her uterus is non-tender and hersymphisio-fundal height is 27 cm. BP is 154/96 mmHg, pulseis 104 bpm and urinalysis reveals ++ of protein. A CTG isperformed and reveals a reduced baseline vari-ability andabsence of accelerations over a one-hour period.

�Q59 A 17-year-old G1 P0 is admitted to hospital at 28 weeks’gestation with reduced fetal movements. She has beenfeeling increasingly uncomfortable today. On examinationher uterus is tense and tender, and her symphysio-fundalheight is 32 cm. Her BP is 96/46 mmHg, pulse is 124 bpmand urinalysis reveals + of protein. Auscultation with aSonicAid reveals a fetal heart rate of 60 bpm.

�Q60 A 26-year-old G2 P1 is attending for a routine anomalyscan at 21 weeks’ gestation. She mentions that she is feelingless fetal movements than she did in her last pregnancy.During the ultrasound examination the fetal heart rateappears normal, but only minimal movement is observed.The sonographer is also concerned about the baby’s postureand the position of its limbs.

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Theme: Vaginal bleeding

Options:

A Placental abruptionB Vaginal traumaC Vasa praeviaD Vulvo-vaginitisE Placenta praeviaF Cervical ectropionG Circumvallate placentaH ShowI Cervical carcinomaJ Foreign body

Lead-in:

For each of the following cases, please select the most likelydiagnosis from the option list. Each option may be used once,more than once or not at all.

�Q61 A 25-year-old primigravida at 30 weeks’ gestation is ad-mitted to the labour ward with moderate fresh vaginalbleeding and abdominal pain, associated with irregularuterine tightenings. On examination her uterus is tenderand irritable. Her blood pressure is 88/46 mmHg, pulse is112 bpm and temperature is 36.9 8C.

�Q62 A 20-year-old primigravida at 38 weeks’ gestation is ad-mitted to the labour ward with fresh vaginal bleeding. Hermembranes ruptured 20 minutes ago and she started bleed-ing immediately after they ruptured. On examination heruterus is soft, her pulse is 88 bpm, BP is 132/75 mmHg andtemperature is 37.0 8C. The fetal heart rate is 90 bpm.Urinalysis is clear.

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�Q63 A 41-year-old G4 P2, who has had two previous Caesareansections, is admitted to the labour ward at 32 weeks’gestation with sudden onset of heavy fresh vaginal bleed-ing. On examination her uterus is soft and non-tender. Herpulse is 120 bpm, BP is 98/52 mmHg and temperature is36.6 8C. The fetal heart rate is 148 bpm. Urinalysis is clear.

�Q64 A 37-year-old refugee of African origin, who is HIV-positive and has only recently arrived in the UK, booksfor ante-natal care at 22 weeks’ gestation. She mentions atwo-month history of heavy, fresh, post-coital bleedingfollowing each episode of intercourse. On examination heruterus is soft and non-tender, and the fetal heart rate is166 bpm.

�Q65 A 22-year-old primigravida presents to the labour wardwith vaginal bleeding at 17 weeks’ gestation. She has had athick, white vaginal discharge and vulval pruritus and sore-ness for the past week; for the past 24 hours she hasobserved blood on wiping herself.

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Complications ofpregnancy

Theme: Hypertensive disorders

Options:

A 24-hour urinary protein measurementB FBC and coagulation profileC Ultrasound scanD 24-hour ambulatory BP measurementE Urea and electrolytesF LFTG Uterine artery DopplerH Renal ultrasound scanI Chest X-rayJ MSU for culture and sensitivity

Lead-in:

For each of the following clinical situations, please select the mostuseful investigation from the option list. Each option may be usedonce, more than once or not at all.

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�Q66 A42-year-old primigravida isundergoing inductionof labourat 36 weeks because of hypertension and proteinuria from31 weeks’ gestation. She is on oral labetolol 200 mg tds.During the first stage of labour she becomes increasinglybreathless and her O2 saturations drop to 91–93%. Youreview her fluid balance chart and find that she is 2500 mlin positive balance.

�Q67 You are asked to see a 25-year-old woman, 30 weeks intoher first pregnancy, with a family history of pre-eclampsia,who was referred by her GP to the hospital with increasingpre-tibial oedema. She is asymptomatic. On admission herBP is 128/75 mmHg and her urine is clear. Symphysio-fundal height is 25 cm and the baby has been active.

�Q68 A community midwife refers a 28-year-old P2 with twonormal pregnancies in the past to the ante-natal clinicbecause of proteinuria. The patient is 24 weeks pregnant,and has made an appointment to see the midwife because ofleft-sided loin pain. On examination her BP is 125/60 mmHg,urinalysis reveals + proteinuria, +++ leucocytes, ++ nitrites.

�Q69 A 23-year-old woman attends the ante-natal clinic at 22weeks’ gestation. In her previous pregnancy she developedsevere early onset pre-eclampsia and fetal growth restric-tion, and had to be delivered by Caesarean section at 31weeks’ gestation. On examination her BP is 100/62 mmHgand her urinalysis is clear. Her detailed anomaly scan yester-day was reported as normal.

�Q70 A 29-year-old G1 P0 with known pre-eclampsia is admit-ted to the labour ward in established labour at 37 weeks’gestation. She is on oral methyldopa 500 mg qds. She isrequesting epidural analgesia.

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Theme: Diabetes in pregnancy

Options:

A Insulin regime and dietary modificationB Metformin and dietary modificationC Termination of pregnancyD Dietary intervention onlyE Induction of labourF BetamethasoneG Caesarean sectionH Glibenclamide and dietary modificationI Folic acidJ Hypostop

Lead-in:

For each of the following clinical situations, please select the mostappropriate management from the option list. Each option may beused once, more than once or not at all.

�Q71 A 36-year-old primigravida is referred by her midwife for aglucose tolerance test at 30 weeks’ gestation because of apositive family history. Her fasting value is 6.2 mmol/l andthe two-hour value is 9.1 mmol/l.

�Q72 A 28-year-old woman with pre-existing Type 1 diabetesis 38 weeks pregnant. Her blood sugar control has beensatisfactory throughout the pregnancy, but an ultrasoundscan at 37 weeks’ gestation suggests an estimated fetalweight of 4.9 kg.

�Q73 A 44-year-old G4 P2 is referred for a glucose tolerance testat 27 weeks’ gestation because of her BMI. Her fasting glucoseis 8 mmol/l and her two-hour glucose level is 12.7 mmol/l.

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�Q74 A 30-year-old woman with recently diagnosed mild ges-tational diabetes, whose blood sugars have been satisfac-tory without drug therapy, is admitted to the labour wardat 29 weeks’ gestation with painful tightenings. On exam-ination she appears to be contracting every 20 minutes, andher cervix is effaced butnotyet dilated.Thebaby ispresentingby the vertex, and the fetal heart rate is satisfactory.

�Q75 A 32-year-old G3 P2 with well-controlled pre-existingType 1 diabetes presents to the hospital at 37 weeks’ gestationon two occasions with reduced fetal movements. Accord-ing to a recent ultrasound scan, the estimated fetal weightis 3.35 kg and amniotic fluid volume is normal. Her firstpregnancy resulted in a stillbirth at 39 weeks’ gestation;the second baby was delivered by the vaginal route at 38weeks’ gestation.

Theme: Collapse

Options:

A EclampsiaB Vasovagal attackC EpilepsyD Cerbrovascular accidentE Pulmonary embolusF Postural hypotensionG Amniotic fluid embolismH Cardiac dysrhythmiaI Hyperventilation syndromeJ Uterine inversion

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Lead-in:

For each of the clinical presentations below, select the most likelyunderlying cause from the list of options. Each option may be usedonce, more than once or not at all.

�Q76 A 21-year-old G1 P0 at 16 weeks’ gestation is admittedto the hospital. She was out shopping with a friend; shesuddenly felt faint whilst queuing at the till, became paleand sweaty and collapsed. The paramedics checked herblood pressure, and found it to be 96/52 mmHg, and herpulse was 90 bpm. Urinalysis is negative. She is nowcompletely asymptomatic but is concerned about the baby.

�Q77 A 29-year-old G2 P1 with gestational diabetes is induced at39 weeks’ gestation because of discomfort associated withpolyhydramnios. She delivers spontaneously after a labourlasting only 45 minutes. A few minutes after the baby andplacenta are delivered she suddenly collapses. Her BP is70/35 mmHg, pulse is 146 bpm and thready, and she iscyanosed. You note that she appears to be bleeding frompuncture sites on her arms.

�Q78 A 39-year-old G1 P0 develops severe pre-eclampsia andlabour is induced at 36 weeks’ gestation. Her blood pres-sure is labile and difficult to control. You are called to seeher when she complains of a headache. Her speech is slurred,and you find her blood pressure to be 238/160 mmHg.Urinalysis reveals ++ of protein. Whilst you are assessingher, the patient suddenly collapses and loses consciousness.

�Q79 A 25-year-old primigravida, who is currently 29 weekspregnant, is brought in by ambulance having collapsed athome. Her partner describes that she suddenly collapsed,her body went stiff and her limbs started to jerk. The attacklasted about two minutes. Her BP is 149/95 mmHg and herpulse is 88 bpm. Urinalysis reveals +++ of protein.

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�Q80 A 33-year-old G2 P1 labours spontaneously at term. Shemakes good progress in labour and delivers a live maleinfant. Syntometrine is administered in the third stage, butthe midwife has difficulty delivering the placenta. She allowsa further 15 minutes and applies controlled cord traction.The cord appears to be lengthening, but the patient sud-denly complains of feeling unwell and collapses.

Theme: Obstetric haemorrhage

Options:

A Rhesus antibody titreB MRI scanC CTGD Fetal blood samplingE Cervical smearF No investigation necessaryG Ultrasound scanH MSU for culture and sensitivityI Apt testJ Cordocentesis

Lead-in:

For each case scenario please select the most useful investigationfrom the option list. Each option can be used once, more than onceor not at all.

�Q81 A 42-year-old G3 P2 who has had two previous Caesareansections is admitted to the labour ward at 31 weeks’ ges-tation with unprovoked, painless, fresh vaginal bleeding.The estimated blood loss is 150–200 ml. Fetal movementshave been normal. Her vital signs are within normal limits,and the fetal heart rate is 145 bpm.

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�Q82 A 23-year-old primigravida, who smokes 20 cigarettes perday, is admitted to the labour ward at 29 weeks’ gestationwith fresh vaginal bleeding. She is also complaining ofabdominal pain and reduced fetal movements. The estim-ated blood loss is approximately 100 ml. Her vital signs arewithin normal limits. At 20 weeks her placenta was reportedto be fundal.

�Q83 A 39-year-old woman who is HIV-positive attends theante-natal clinic at 26 weeks’ gestation. She complains ofbloodstained vaginal discharge and recurrent painless post-coital bleeding for the past six weeks. Fetal movementshave been normal.

�Q84 A 26-year-old primigravida, who has had an uneventfulpregnancy, telephones the hospital for advice. She is cur-rently at 39 weeks’ gestation and has had backache andirregular tightenings for the past 48 hours. The tighteninghas become more regular today, and she has noticed blood-stained mucus per vaginam on wiping herself. Fetal move-ments have been normal.

�Q85 A 19-year-old primigravida who is Rhesus-negative at-tends for routine ante-natal care at 34 weeks’ gestation.She has failed to attend her last two appointments, and hasnot seen her midwife since 22 weeks’ gestation. A detailedultrasound scan at 24 weeks’ gestation did not reveal anyabnormalities. She reports having had two episodes ofpainless vaginal bleeding at 25 and 26 weeks’ gestation.Fetal movements have been normal, and her symphysio-fundal height is 36 cm.

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Theme: Fetal growth disorders

Options:

A TriploidyB Beckwith–Wiedeman syndromeC Gestational diabetesD Marijuana useE ObesityF Pre-eclampsiaG Constitutional small-for-datesH Amphetamine useI Congenital cytomegalovirusJ Antiphospholipid syndrome

Lead-in:

For each case scenario please select the most likely cause from theoption list. Each option can be used once, more than once or notat all.

�Q86 A 30-year-old G1 P0 with a BMI of 24 is delivered byemergency Caesarean section for intrapartum fetal distressat 40 weeks’ gestation. Her pregnancy is reported to havebeen uncomplicated. The baby’s birth weight is 2.1 kg, andon examination, multiple petechial haemorrhages, jaun-dice and hepatosplenomegaly are noted.

�Q87 A homeless 20-year-old G1 P0 with a BMI of 18, who hasonly attended one ante-natal appointment during her preg-nancy, is admitted with severe abdominal pain and vaginalbleeding at approximately 34 weeks’ gestation. Her BP is130/88 mmHg and urinalysis is negative. She is deliveredby emergency Caesarean section and placental abruptionis confirmed. The baby, whose birth weight is below the3rd centile, appears jittery and irritable.

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�Q88 A 39-year-old G6 P1 with a BMI of 29, who has had fourmiscarriages in the past and a pulmonary embolism duringher last pregnancy, is admitted to the labour ward withabdominal pain and vaginal bleeding at 35 weeks’ ges-tation. Her BP is 128/88 mmHg and urinalysis is negative.She undergoes an emergency Caesarean section for suspectedplacental abruption. The baby’s weight is below the 3rdcentile, and the placenta is small with multiple thrombi andinfarcts.

�Q89 A 42-year-old G4 P3 with a BMI of 38 goes into spon-taneous labour at 37 weeks’ gestation. Her labour prog-resses well; however, the delivery is complicated by mildshoulder dystocia. The baby’s birth weight is 4.8 kg. Dur-ing the first 48 hours of life the baby experiences recurrentepisodes of hypoglycaemia.

�Q90 A 26-year-old G1 P0 of Indo-Asian origin with a BMI of 19delivers spontaneously at 40 weeks’ gestation. The baby,whose birth weight is on the 5th centile, is well and has anunremarkable neonatal course.

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