Empower resource Management for Analysis of Workflow and System Utilization. Workshop … ·...

©2013 Waters Corporation 1

Empower resource Management for Analysis

of Workflow and System Utilization.

Workshop C2

Gilles Bassard / Ömer Yilmaz


Empower Driven Services - A Suite of Services

Empower Environment

Waters LC and MS

Instrument Service

Agilent LC and GC

Instrument Qualification

Software Qualification

Validation

Compliance Asset

Management

Asset Care

Connections INSIGHT

iRequests

Resource Management

Report

Resource and Workflow

Management

Service Event Management

Software Compliance

Audit

Empower Database

Server Audit


Throughput Challenges in Analytical Labs Today

Optimizing multiple labs,

working on multiple projects, on multiple time lines and goals

to decrease costs and maximize asset utilization

………is a challenge.

Standards and sample preparation

Data acquisition and processing

Data compilation and management


What are the Key Impacts on Your Business?

Greater Efficiency

Manage Capacity

Drive Continuous Improvement Initiatives

Optimize Resource Utilization

Improve Workflow

Comply with Regulatory Compliance

Reduce Costs


What is Your Laboratory Overall Usage Pattern?

Significant Improvement


What is Your Individual System Usage?

From a high level, to a low level, by instrument or by time period

How are the instruments really being used?

System 4 used significantly less

than other systems in the lab


Can You Predict When to Schedule Maintenance?

Set your PM schedule based on actual usage of each individual system and…


Have You Considered New Technology Adoption?

By switching from traditional HPLC to UPLC technology –

potential time savings of two days for specific instrument method


Manufactured Drug In-process Timeline Using Established Lab Technology

DAYS 1 2 6 3 4 5

RxN #1 (12 hours)

HPLC

Data Analysis & Sign-Off (1 hour)

In-Process Monitoring #1 (6 hours)

RxN #2 (8 hours)



HPLC

HPLC

RxN #3 (19 hours)


Analysis & Sign-Off (1 hour)

HPLC

RxN #4 (7 hours)

Release & Sign-Off (1 hour)


6 hours per HPLC

monitoring step

Total of 24 hours per

batch


Manufactured Drug In-process Timeline Using Latest Lab Technology

DAYS 1 2 6 3 4 5

RxN #1 (12 hours)


In-Process Monitoring #1 (1 hr, 40 min)

RxN #2 (8 hours)

RxN #3 (19 hours)

RxN #4 (7 hours)







Bulk drug substance shipped to

Formulation

35% faster

Solvent usage reduced by 50%

for this method

savings in purchasing &

disposal costs:

$20,000/year

1 hour 40 minutes per UPLC

monitoring step

Total of < 7 hours per batch


Where are the Bottlenecks in the Laboratory Workflow?

Number of Days to Sign-Off

34 vs 7 days


What is Your Audit Trail Trying to Tell You?

The Audit Trail gives a good indication of the usage of

Empower overall, and can highlight a number of issues


Do You Measure Processing Method Robustness?

Examining the number of re-processes, and the % of

manual processing gives an indication of method robustness

Some methods show 100% manual

processing


How Many Messages are in Your Message Center?

Analysis of the Message Center can uncover any underlying

issues within the system


Are User Comments Meeting Compliance Requirements?

Examining the comments that users are entering for

methods and method changes can assure compliance


Do You Know the Number of Versions for Each method…and Why?

Examining a method summary listing number of versions

could identify compliance concerns


Do You Monitor Your Service Metrics?

Response time:

• more than 3 days • is there an issue?

Repair duration:

• more than 3 days • why?


Consultation Services and Resource Management Reporting

Consultation Process

– Waters Business Impact Consultant will work with you to:

o Understand your business objectives and goals to determine

how these affect your laboratories

o Gain understanding of your processes within your Empower

environment

o Mine data and service information in a secure manner from

your Empower database

o Customize analytics and reporting

– Meet with your key team members and Waters personnel

supporting your account

o Deliver recommendations that provide meaningful business

impact for your organization


Resource Management Report

Service Event Information

End User Feedback


Consultative to Professional Services

Optimize process flow

Improve Methods

Improve instrument utilization

Manage Empower efficiently

Recover $$ on old assets

Manage budgets effectively

Reduce user errors

Free up lab space

Harmonize qualification

Customize Maintenance

Monitor impact of changes

Consultative Service Professional Services


Resource Management Report

Executive Summary

Business Analysis and Objectives

Technical Analysis

Service Analysis

Summary of Recommendations


Resource Management Report – Technical Analysis

Resource Utilization

– System / user usage patterns

– Detailed UPLC Analysis

– Workstation vs LACE vs Citrix

– Column Usage

Laboratory Workflow

– Detailed workflow analysis

– Processing method complexity

– Manual integration


Resource Management Report – Technical Analysis

Administration

– LACE reboots

– Specific Message Center analysis

– Project Audit trails

– Sample Set recovery

– Custom field usage

– Administrative overhead

Compliance

– AQT usage

– sQT usage

– System Policies

– Project Audit trail investigations

Security

– System Policies

– Logons


Resource Management Report – Service Analytics

Service Analysis

– Time to service

– Instruments with multiple unscheduled service events

– Status of Performance Maintenance service events


Empower Driven Services

EDS 365v1


Empower Driven Services EDS 365

Giving EDS (Empower Driven Services) customers the ability

to obtain and monitor metrics related to their Empower

system.

Metrics will be in addition to, and complementary to the

delivered Resource Management Report.

The delivery mechanism for initial release of EDS 365 is

Business Intelligence style dashboards accessed by

customers on site by installing an EDSIP image and

collecting data on a scheduled basis.


EDS 365 System Usage by Date (1)

Empower Environment


EDS 365 System Usage by Date (2)

Empower Environment


EDS 365 System Usage – Days used

Empower Environment


EDS 365 System Usage – Days used (2)

Empower Environment


EDS 365 System % Usage

Empower Environment


EDS 365 System % Usage patterns

Empower Environment


EDS 365 Message Center summary (1)

Empower Environment



Empower Environment


EDS 365 Message Center Details


What are the Key Impacts on Your Business?

Greater Efficiency

Manage Capacity

Drive Continuous Improvement Initiatives

Optimize Resource Utilization

Improve Workflow

Comply with Regulatory Compliance

Reduce Costs

Monitor diverse aspects of the Empower Network and workflow to help focus on system utilization, training needs, method productivity and provide justifications for laboratory needs.

Resource Management Report and

EDS365


Questions

Empower resource Management for Analysis of Workflow and System Utilization. Workshop … ·...

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