Emerging Infectious Diseases

NAOEM Scientific Conference

October 27, 2015

Rodd E. Marcum, MD, MPH, FACP

© National Museum of Health and Medicine, Washington, D.C., United States

Bryan van der Beek Inside the ICU Tan Tock Seng Hospital, Singapore

Agenda

• Impacts of Emerging Infectious Diseases (EID’s) • Zoonotic interface • Remerging infectious diseases • Newly emerging infectious diseases • EID resources

- The views I am about to express are my own and do not necessarily represent the views of the Army or the DoD

- I have no financial disclosures

Societal Impacts

• Social • Political • Economic • Food & agriculture • Life sciences • Health care

Economic Impact

Zoonotic connection

1 Gortazar C, Reperant LA, Kuiken T, de la Fuente J, Boadella M, Martínez-Lopez B, et al. (2014) Crossing the Interspecies Barrier: Opening the Door to Zoonotic Pathogens. PLoS Pathog 10(6): e1004129. doi:10.1371/journal.ppat.1004129

Global EID’s

Image courtesy Morens et al. Nature 430:242, 2004

Re-emerging Infectious Diseases

• Drug-resistant infections • Multi-drug resistant Tuberculosis (MDR TB) • Vancomycin resistant Enterococcus (VRE) • Carbapenam resistant Enterococcus (CRE) • Methicillin resistant Staphylococcus Aureus (MRSA) • Clostridium Difficile (C.Diff)

Re-emerging Infectious Diseases

• Diphtheria • Cholera • Yellow Fever • Bubonic plague • Dengue • Chikungunya • Polio Source cdc.gov

Emerging Infectious Diseases • West Nile virus • Novel Coronavirus

• Severe Adult Respiratory Syndrome (SARS) • Middle East Coronavirus Syndrome (MERS-CoV)

• Enterovirus Serovar D-68 • Novel Influenza virus • Nipah • Zika • Hendra • Naegleria Fowleri • Bourbon virus • Heartland virus

Photo courtesy cdc.gov

Image courtesy sciencemag.org

Photo courtesy reburn.com

Nipah Virus

Photo courtesy topnews.com

Neti Pot Demo by Dan Machold Photo courtesy buzzfeed.com

Number of Case-reports of Primary Amebic Meningoencephalitis Caused by Naegleria fowleri by State of Exposure*— United States, 1962–2014)

Bourbon virus

Image courtesy medscape.com

Resources

Thank you for your valuable time!

Images courtesy google images