Embryology of the Reproductive Organs The entire process of sexual development depends on a...

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Embryology of the Reproductive Organs The entire process of sexual development depends on a sequential series of interactions between regulatory factors and genetic machinery.

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Page 1: Embryology of the Reproductive Organs The entire process of sexual development depends on a sequential series of interactions between regulatory factors.

Embryology of the Reproductive Organs

The entire process of sexual development depends on a

sequential series of interactions between regulatory factors and

genetic machinery.

Page 2: Embryology of the Reproductive Organs The entire process of sexual development depends on a sequential series of interactions between regulatory factors.

Stages of Sexual Determination (Differentiation)

1. Chromosomal Determination

XX or XY

2. Gonadal Determination

Ovary or testes

3. Phenotypic determination

What do sex organs look like

Page 3: Embryology of the Reproductive Organs The entire process of sexual development depends on a sequential series of interactions between regulatory factors.

1. Chromosomal DeterminationOvum

22 Autosomes

1 X chromosome

Sperm

22 Autosomes

1 X chromosome

or

1 Y chromosome

Zygote = 46 XX

or

46 XY

Page 4: Embryology of the Reproductive Organs The entire process of sexual development depends on a sequential series of interactions between regulatory factors.

Cleavage

Page 5: Embryology of the Reproductive Organs The entire process of sexual development depends on a sequential series of interactions between regulatory factors.

Blastocyst

Page 6: Embryology of the Reproductive Organs The entire process of sexual development depends on a sequential series of interactions between regulatory factors.

Implantation

Page 7: Embryology of the Reproductive Organs The entire process of sexual development depends on a sequential series of interactions between regulatory factors.

Formation of the Placenta

Page 8: Embryology of the Reproductive Organs The entire process of sexual development depends on a sequential series of interactions between regulatory factors.

Primordial Germ Cells

Page 9: Embryology of the Reproductive Organs The entire process of sexual development depends on a sequential series of interactions between regulatory factors.

3 Week Embryo

Page 10: Embryology of the Reproductive Organs The entire process of sexual development depends on a sequential series of interactions between regulatory factors.

6 Weeks embryo

Page 11: Embryology of the Reproductive Organs The entire process of sexual development depends on a sequential series of interactions between regulatory factors.

6 weeks

Page 12: Embryology of the Reproductive Organs The entire process of sexual development depends on a sequential series of interactions between regulatory factors.

At Six Weeks

Primordial Germ Cells

Genital/GonadalRidge

Page 13: Embryology of the Reproductive Organs The entire process of sexual development depends on a sequential series of interactions between regulatory factors.

TDF

Page 14: Embryology of the Reproductive Organs The entire process of sexual development depends on a sequential series of interactions between regulatory factors.

Testes Determining Factor

TDF is a gene on the Y chromosome that converts the Gonadal/Genital ridge to a testes

Inside a testes you have:- Seminiferous tubules – Spermatogonia inside- Sertoli cells – Produces MIF (Mullerian inhibiting

Factor in embryo.- Interstitial cells – Produce Testosterone

Page 15: Embryology of the Reproductive Organs The entire process of sexual development depends on a sequential series of interactions between regulatory factors.

Gonadal

Ridge

Mullerian Duct

Wolffian Duct

Page 16: Embryology of the Reproductive Organs The entire process of sexual development depends on a sequential series of interactions between regulatory factors.

Gonadal Ridge

Mullerian Duct

Wolffian Duct

Page 17: Embryology of the Reproductive Organs The entire process of sexual development depends on a sequential series of interactions between regulatory factors.

Epidydidimis

Vas deferens

Degenerating Mullerian Duct

Seminal Vesicle

Page 18: Embryology of the Reproductive Organs The entire process of sexual development depends on a sequential series of interactions between regulatory factors.

Ovaries

Uterus

Fallopian Tubes

Upper Part of Vagina

Page 19: Embryology of the Reproductive Organs The entire process of sexual development depends on a sequential series of interactions between regulatory factors.

Undifferentiated external

Genital tubercle

Genital foldGenital groove

Labioscrotal swelling

Page 20: Embryology of the Reproductive Organs The entire process of sexual development depends on a sequential series of interactions between regulatory factors.

Undifferentiated external

Genital Tubercle

Genital Fold

Genital Groove

Labioscrotal Swelling

Page 21: Embryology of the Reproductive Organs The entire process of sexual development depends on a sequential series of interactions between regulatory factors.

Undifferentiated Stage

Genital Tubercle

Genital Fold

Genital Groove

Labioscrotal Swelling

Page 22: Embryology of the Reproductive Organs The entire process of sexual development depends on a sequential series of interactions between regulatory factors.

Genital Tubercle

Glans Penis

Genital Fold

Genital Groove

Labioscrotal Swelling

Penile Rafe

Urethra

Scrotal Sac

Page 23: Embryology of the Reproductive Organs The entire process of sexual development depends on a sequential series of interactions between regulatory factors.

Genital Tubercle

Clitoris

Genital Fold

Labia Minor

Genital Groove

Labioscrotal Swelling

Labia Major

Vaginal and Urethral Opening

Page 24: Embryology of the Reproductive Organs The entire process of sexual development depends on a sequential series of interactions between regulatory factors.
Page 25: Embryology of the Reproductive Organs The entire process of sexual development depends on a sequential series of interactions between regulatory factors.
Page 26: Embryology of the Reproductive Organs The entire process of sexual development depends on a sequential series of interactions between regulatory factors.

7 Months 8 Months

Page 27: Embryology of the Reproductive Organs The entire process of sexual development depends on a sequential series of interactions between regulatory factors.

Transabdominal movement

Formation of the Inguinal Canal

Movement into scrotal sac

Page 28: Embryology of the Reproductive Organs The entire process of sexual development depends on a sequential series of interactions between regulatory factors.

1. Gubernaculum

2. Phallus

3. Inguinal Canal

4. Testes

5. Abdominal cavity

6. Vas deferens

Page 29: Embryology of the Reproductive Organs The entire process of sexual development depends on a sequential series of interactions between regulatory factors.

Masculanize the Wolffian Duct

Testosterone

Page 30: Embryology of the Reproductive Organs The entire process of sexual development depends on a sequential series of interactions between regulatory factors.

Masculanize the external genitals

Page 31: Embryology of the Reproductive Organs The entire process of sexual development depends on a sequential series of interactions between regulatory factors.

Masculanize the Brain


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