ELASTIN - POWERPOINT
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Transcript of ELASTIN - POWERPOINT
ELASTIN
Hizon, Kenneth EdwardIleto, Olga EleaneLimun, Rollen JerlandMT12214
Elastin
Is found in skin and tissue of the body. It is a protein in connective tissue that
is elastic and allows many tissues in the body to resume their shape after stretching or contracting.
It is a protein that helps to keep our skin flexible but tight.
It also helps keep skin smooth as it stretches to accommodate normal activities like flexing a muscle or opening and closing the mouth to talk or eat.
Elastin Elastin are like
rubber bands. It helps skin to
return to its original position when it is poked or pinched
Elastin
Multiple copies of the tropoelastin protein attach to one another and are processed to form a mature protein
Tropoelastin has some secondary structure, mainly alpha-helices and beta-turns but does not form any stable tertiary structure. Even the secondary structure can be lost as the microenvironment changes until they are linked into an elastin fiber which stabilizes them.
It is created by fibroblasts which are a type of connective tissues.
The capacity of fibroblasts goes on decreasing as we grow older.
Amino Acids in Elastin
Composed of amino acids. Hexapeptide 2 Valine, 2 Glycine, Alanine and Proline.
Structures
Secondary Structure
Desmosine and Isodesmosine
Four lysine chains can be combined to form a desmosine cross-link
Conformation and Folding of Elastin
Quaternary Structure
Tertiary Structure
Damaged Elastin
Once our body tissues loose their elasticity, they can never regain it.
It can be reduced or damaged due to various reasons like stress, hormones and smoking
It can be also due to aging. As the body and its organs loose elasticity,
our body’s functioning is also affected. Elastin is also damaged due to
overexposure to sunlight
Elastin
Used for skin-care products Anti-aging creams Skin Renewing Face Treatment Body Lotion Used as a coating on collagen patches for
injuries. The addition of an active form of elastin to the
skin’s surface has the potential to reduce the requirement for drugs or cosmetic surgery procedures, making it a highly cost effective and safe alternative.