Effect of 21-day Holistic Therapy at

“Our Native Village Eco Resorts”

on Diabetes Mellitus as assessed by blood glucose levels and consumption of oral hypoglycemic

agents

Our Native Village Eco Resorts110, 1st Floor

2nd Cross 4th MainH.A.L III Stage, Bangalore -560075

Sequence Of Presentation

Introduction Study Objectives Study End Points Study Procedure Results

Clinical data Medication Usage

Conclusion

Human body has the inbuilt capability of healing itself completely of diseases. At Our Native Village, an eco-resort for holistic health, an environment is created that is conducive for the body’s self-healing mechanism to work.

The fundamental belief behind the 21 day holistic healing program is that the human system in general and the body in specific, has the capability of healing itself completely of diseases of the body, mind and soul.

The 21-day holistic health protocol for diabetes practiced at Our Native Village is a combination of ayurvedic therapies, acupressure, naturopathy, sound healing, meditation, yoga, pranayams, mudras, re-birthing breath work, past life regression, and mind body medicine knowledge.

Introduction

Primary Objective:

Study the effect of 21 day holistic therapy on reduction in blood glucose level.

Secondary Objective:

Study the effect of 21 day holistic therapy on lipid levels, HbA1c and the consumption of antidiabetic medications.

Study Objectives

Study End Points

Primary endpoint:

Reduction in fasting blood glucose from baseline to end of the study period (21 days).

Reduction in postprandial blood glucose from baseline to end of the study period (21 days).

Secondary endpoints:

Change in HbA1C from baseline to end of the study period (21 days).

Change in the use of antidiabetic medications from baseline to end of the study period (21 days).

Change in cholesterol, triglyceride, LDL, VLDL, HDL from baseline to end of the study period (21 days).

21 subjects enrolled in the study Parameters measured (at baseline, day 0 and end of study, day

21)o Fasting Blood Glucose Postprandial Blood Glucose HbA1c (glycosylated hemoglobin) Cholesterol Triglyceride Direct LDL cholesterol Very low density lipoprotein HDL cholesterol Antidiabetic medication usage

Study Procedure

Lab parameters were compared before and after the administration of holistic therapy.

Results

Change in Lab parameters at the end of the 21 day Holistic Therapy

Sl. no Lab ParametersReduction (No of

Subjects)

1 Fasting Blood Glucose 12

2 Blood Glucose, Post-prandial 14

3 Cholesterol 11

4 Triglycerides 13

5 Direct LDL cholestrol 10

6 Very low density lipoprotein 14

7Glycosylated hemoglobin (HBA1C) 20

Sl.no Lab ParametersElevation (No of

Subjects)

1 Cholesterol HDL 6

Results: Fasting Glucose

Out of 21 subjects enrolled in the study, 12 subjects showed reduction in fasting glucose levels at the end of 21 day holistic therapy.

Mean fasting glucose value reduced from155.29 mg/dl to 141.71 mg/dl.

Results: PP Glucose

Out of 21 subjects enrolled in the study, 14 subjects showed reduction in postprandial glucose levels at the end of 21 day holistic therapy.

Mean postprandial glucose value reduced from 240.91 mg/dl to 211.29 mg/dl - a fall of about 29 units.

Results: HbA1c

Out of 21 subjects enrolled in the study, 20 subjects showed reduction in HbA1c levels at the end of 21 day holistic therapy.

Mean glycosylated hemoglobin showed a decrease from 8.44% to 7.72%.

Results: Triglycerides

Out of 21 subjects enrolled in the study, 13 subjects showed reduction in triglycerides level at the end of 21 day holistic therapy.

Mean triglyceride level reduced from 167.24 mg/dl to 158.52 mg/dl.

Results: VLDL

Out of 21 subjects enrolled in the study, 14 subjects showed reduction in VLDL (very low density lipoprotein) level at the end of 21 day holistic therapy

Mean VLDL values showed a reduction from 33.45 to 30.94 mg/dl.

Sl. no Lab ParametersMaximum reduction

1 Fasting Glucose 91 mg/dL2 Glucose, Post-prandial 244 mg/dL3 Cholesterol 70 mg/dL4 Triglycerides 104 mg/dL5 Direct LDL cholestrol 46 mg/dL6 Chol/HDL ratio 1.67 LDL/HDL ratio 1.58 Very low density lipoprotein 21.8 mg/dL

9Glycosylated hemoglobin

(HBA1C) 2 mg/dL

Sl.no Lab Parameters Maximum increase1 Cholesterol HDL 7 mg/dL

Maximum Change seen in Lab parameters at the end of 21- day Holistic Therapy

Results: Maximum Change

Medication Usage

Sl. no

Study Parameter No. of subject

s1 Total number of subjects in the study* 21

2 Total number of subjects for whom the antidiabetic medications were completely stopped

6

3 Total number of subjects for whom at least 1 antidiabetic medication was stopped

6

4 Total number of subjects for whom dosage of at least 1 antidiabetic medication was decreased

4

5 Total number of subjects with no change in dosage of antidiabetic medication

7

6 Total number of subjects with increase in dosage of at least 1 antidiabetic medication**

1

Antidiabetic Medication Usage at the End of Holistic Therapy

*No information on prescreening medication for 1 subject and 1 subject was not on any antidiabetic medication.**No information for 3 antidiabetic medications at the end of study period.

Study Conclusion

With 21 day dietary therapy (plant based diet) and other modalities of holistic healing like yoga, meditation, acupressure etc., reduction was seen not only in blood sugar levels (fasting and postprandial blood glucose), HbA1c but also some of the lipid profile parameters like triglycerides and VLDL. The consumption of antidiabetic medication was also reduced at the end of the 21 day period.

The results of the study conducted by “Our Native Village Eco Resorts” on the effect of 21-day Holistic Therapy on Diabetes Mellitus indicate that the program supporting lifestyle change can be very effective in diabetes prevention and control.