ADRENALINEAction N Stimulates beta receptors in lung.N Relaxes bronchial smooth muscle. N Increases vital capacityN Increases BP, HR, PR N Decreases airway resistance.

N AsthmaN BronchitisN EmphysemaN All cardiac arrest, anaphylaxisN Used for symptomatic bradycardia.N Relief of bronchospasm occurring during anesthesiaN Exercised-induced bronchospasm

Contraindications N With angle-closure glaucoma, shock (other than anaphylactic shock), organic brain damage, cardiac dilation, arrhythmias, coronary insufficiency, or cerebral arteriosclerosis. Also contraindicated in patient receiving general anesthesia with halogenated hydrocarbons or cyclopropane and in patients in labor (may delay second stage)N In conjunction with local anesthesia, epinephrine is contraindicated for use in finger, toes, ears, nose, and genitalia.N In pregnant woman, drug is contraindicated.N In breast feeding do not use the drug or stop breast feeding.

Nursing Management1. Monitor V/S. and check for cardiac dysrrhythmias2. Drug increases rigidity and tremor in patients with Parkinsons disease 3. Epinephrine therapy interferes with tests for urinary catecholamine 4. Avoid IM use of parenteral suspension into buttocks. Gas gangrene may occur 5. Massage site after IM injection to counteract possible vasoconstriction. 6. Observe patient closely for adverse reactions. Notify doctor if adverse reaction develop 7. If blood pressure increases sharply, rapid-acting vasodilators such as nitrates or alpha blockers can be given to counteract

ATROPINE[ Pre-op meds/pre-anesthetic meds[ To restore cardiac rate and arterial pressure during anesthesia when vagal[ To lessen the degree of A-V heart block[ To overcome severe carotid sinus reflex[ Antidote for cholinergic toxicity

Contraindications[ Hypersensitivity[ With acute angle closure glaucoma, obstructive uropathy, obstructive disease of GI tract, paralytic ileus, toxic megacolon, intestinal atony, unstable CV status in acute hemorrhage, asthma, or myasthenia gravis.[ Pregnant women.

Nursing ManagementN Monitor VS.N Report HRN Monitor for constipation, oliguria.N Instruct to take 30 mins before mealsN Eat foods high in fiber and drink plenty fluids.N Can cause photophobiaN Instruct client not to drive a motor vehicle or participate in activities requiring alertness.N Advise to use hard candy, ice chips, etc. for dry mouth

ADENOSINE

AMIODARONE Life threatening recurrent arrhythmias Ventricular fibrillation Ventricular tachycardia

Contraindications Severe sinus node dysfunction 2nd or 3rd degree AV block Hypersensitivity

Nursing Management Assess cardiovascular status before therapy Assess pulmonary, hepatic and thyroid function before and during therapy Monitor fluid and electrolytes, I&O, K, Na and Cl Monitor ECG, BP Assess vision

CA CLMild hypocalcemia due to neonatal tetany, tetany due to parathyroid deficiency or vitamin D deficiency, and alkalosis.Prophylaxix of hypocalcemia during exchange transfusions.Intestinal malabsorption.Adjunct to treat insect bites or stings to relieve muscle cramping.Depression due to magnesium overdosage.Acute symptoms of lead colic.Rickets, osteomalacia.Reverse symptoms of verapamil overdosage.Decrease capillary permeability in allergic conditions, nonthrombocytopenic purpura, and exudative dermatoses.Pruritus due to certain drugs.Hyperkalemia to antagonize cardiac toxicity.

LIDOCAINEIndication

Anesthesia

Arrhythmias

Control of Status epilepticus refractory to other treatments

VASSOPRESSINIncrease permeability of renal tubular epithelium to adenosine monophosphate and water, the epithelium promotes reabsorption of water and concentrated urineIndication Diabetes Insipidus Abdominal Distention GI bleeding Esophageal varices

Nursing Management Give 1-2 glass of H20 to reduce adverse reactions and improve therapeutic response Warm vasopressin in your hands and mixed until it is distributed evenly in the solution Monitor urine Sp. Gravity and I&O to aid evaluation of drug effectiveness

NAHCO3

DOPAMINE

DOBUTAMINE

NOR ADRENALINE

DORMICUMProvides sedation/ anxiolysis/ amnesia during therapeutic, diagnostic, or radiographic procedures (conscious sedation). Aids in the induction of anesthesia and as part of balanced anesthesia. As a continuous infusion, provides sedation of mechanically ventilated patients during anesthesia or in a critical care setting, Status epilepticus.

FLUMAZENIL

FRUSEMIDEAction

Inhibits Na and Cl reabsorption at the proximal and distal tubules and in the ascending loop of Henle

Indication

[ Acute pulmonary edema

[ Edema

[ HypertensionSide Effects/Adverse ReactionsSigns of hypotension, hypokalemia and hyperglycemia

Contraindications [ Hypersensitivity[ Anuria

Nursing Management1. Monitor wt., BP and PR2. Monitor fluid, I&O, electrolyte, BUN and CO2 levels frequently3. WOF signs of hypokalemia4. Monitor uric acid levels5. Monitor glucose levels esp in DM pts

D50-50

MGSO4Seizures associated with toxemia of pregnancy, epilepsy, or when abnormally low levels of magnewium may be a contributing factor in convulsions, such as in hypothyroidism or glomerulonephritis. For eclampsi, IV use is restricted to control of life-threatening seizures.Acute nephritis in children to control hypertension, encephalopathy, and seizures.Replacement therapy in magnesium deficiency.Adjunct in total parenteral nutrition.Laxative.

NALOXONEComplete or partial reversal of opiod depression, including respiratory depression, induced by natural and synthetic opiods. Adjunctive agent to increase blood pressure in the management of septic shock

KCL

DIAZEPAM

PROPOFOL