Generic name Mechanism of action indication Side effect contraindication Nursing consideration

Erdosteine( ectrin)

. Erdosteine contains two sulfhydryl groups, which are freed after metabolic transformation in the liver. The liberated sulfhydryl groups break the disulphide bonds, which hold the glycoprotein fibres of mucus together. This makes the bronchial secretions more fluid and enhances elimination.

Treatment of acute bronchitis, chronic bronchitis and its exacerbations. Respiratory disorders characterized by abnormal bronchial secretions and impaired mucus transport.

No gastrointestinal nor systemic side effects due to Ectrin have been observed

Known hypersensitivity to erdosteine. Because of a possible interference of erdosteine metabolites with the methionine metabolism, erdosteine is contraindicated in patients suffering from hepatic cirrhosis and deficiency of the cystathionine-synthetase enzyme.Suspension: Phenylketonuria, due to the presence of aspartame.

This drug can be taken with or without food• For the reason that of a probable intrusion of erdosteine metabolites with the methionine metabolism, erdosteine is no recommended in subjects experiencing hepatic cirrhosis and insufficiency of the cystathionine synthetase enzyme.• Ectrin Suspension is also contraindicated for Phenylketonuria, because of existence of aspartame.