E.Coli Med TECH

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E.Coli 0157 h7



What is E.Coli ?

` Escherichia coli (E. coli) is a bacterium thatcommonly lives in the intestines of people and

animals . There are many types of E.Coli . E.Coli

0157 h7 is the most common and dangerous strain (

type ) of E.Coli .



E.Coli 0157 h7

` E coli O157:H7 is a strain of EHEC. It causes colitis

and bloody diarrhea by producing a toxin called

Shiga toxin, which damages the intestines.



Where can and how can you be infected

with E. Coli ?

` Eating undercooked ground beef (the inside is pink)

` Drinking contaminated (impure) water

` Drinking unpasteurized (raw) milk



History

` Theodore von

Escherich, a German

bacteriologist,

discovered the

bacterium Escherichia

coli in 1885.

` It was first recognized

as a cause of illness

during an outbreak in1982 due to

contaminated meat.



The bacteria E.Coli

` 2 microbes in length

` Rod shaped

` Small pills for mobility

Scientific classification

Domain:Bacteria

Phylum:Proteobacteria

Class:GammaProteobacteria

Order:Enterobacteriales

Family:

Enterobacteriacea

e

Genus:Escherichia

Species:E. coli



S ymptoms

` Severe stomach cramps and stomach tenderness.

` Diarrhea, watery at first, but often becoming very

bloody.

` Passing small amounts of urine

` Nausea and vomiting.

` Weakness

` Fever



Detection and elimination

` ³The Colitag Test is used

on water and food ( takes

about 18 to 24 Hrs . It

incorporates many tests,

namely: (1) detection of

a chemical used for gas

and acid in E. Coli , (2)

reaction with E. coli ¶s

waste to produce a red

stain, and (3) flooding thesample with chemicals,

which are then exposed to

a UV light. If they

fluoresce, E. coli is

present. ¶¶



Detection and elimination (conti«)

` ³The (LAL) test is used

for medical equipment

and injections, and

takes at least 1 hour. It

uses horseshoe crabblood, which clots when

exposed to broken

down bacteria

(endotoxins).´



Detection and elimination (conti«)

` ³The SMART -II E. coli

test takes 8 or 24

hours, in which enriched

media is flooded

with colloidal goldantibodies. If E. coli is

present, they bond, and

a gold line forms

on the test strip.´



What can E.Coli o157 h7 cause

` E.Coli can cause Hemolytic Uremic Syndrome.

HUS is a disease that destroys the red blood

cells.



What can E.Coli Cause conti«

Thrombotic

thrombocytopenic purpura

(TTP) is a blood disorder

that causes blood clots to

form in small bloodvessels around the body,

and leads to a low platelet

count.

Complications

- Kidney failure

- Nervous system problems

- Severe bleeding

- Stroke



T reatment

` Most people recover within 5 ± 10 days without

antibiotics .

` the replacement of fluids and electrolytes to prevent

dehydration . Infection with E. coli 0157:H7 should

be treated by a physician` Some Studies have proven that antibiotics use can

increase your chance of developing HUS

Antibiotic resistance is becoming a growing problem

` Blood transfusions and kidney dialysis people whodevelop HUS



References

` http://dev.nsta.org/evwebs/2217/history.htmm

` http://www.medicinenet.com/e_coli__0157h7/pag

e3.htm

`

http://www.cdc.gov/nczved/dfbmd/disease_listing/stec_gi.html

E.Coli Med TECH

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