약학정보원 · 2016. 10. 11. · 20B24 240 10 mggt 100 m 80 10 mg P450 cytochrome P450 3A4011...

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Transcript of 약학정보원 · 2016. 10. 11. · 20B24 240 10 mggt 100 m 80 10 mg P450 cytochrome P450 3A4011...

Page 1: 약학정보원 · 2016. 10. 11. · 20B24 240 10 mggt 100 m 80 10 mg P450 cytochrome P450 3A4011 2) 3) 01 cytochrome P450 3A4 01 cytochrome P450 3A4 4) cytochrome P450 3A4 gg + P450
Page 2: 약학정보원 · 2016. 10. 11. · 20B24 240 10 mggt 100 m 80 10 mg P450 cytochrome P450 3A4011 2) 3) 01 cytochrome P450 3A4 01 cytochrome P450 3A4 4) cytochrome P450 3A4 gg + P450

Herbal Tea Extracts Inhibit Cytochrome P450 3A4 in Vitro

Herbal Tea Extracts Inhibit Cytochrome P450 3A4 in Vitro

A Model of the Membrane-bound Cytochrome b5 -Cytochrome P450 ...

A Model of the Membrane-bound Cytochrome b5 -Cytochrome P450 ...

Identification and characterization of cytochrome P450 1232A24 …eprints.whiterose.ac.uk/143786/1/Author_Accepted... · 2020. 9. 16. · 2 Summary Cytochrome P450 monooxygenases

Identification and characterization of cytochrome P450 1232A24 …eprints.whiterose.ac.uk/143786/1/Author_Accepted... · 2020. 9. 16. · 2 Summary Cytochrome P450 monooxygenases

Functional Investigations of Cytochrome P450 3A4...It has been more than fifty years since Garfinkel (2) and (Klingenberg (3) first reported the existence of an unusual cytochrome

Functional Investigations of Cytochrome P450 3A4...It has been more than fifty years since Garfinkel (2) and (Klingenberg (3) first reported the existence of an unusual cytochrome

The cytochrome P450 - Leeds Beckett Universityeprints.leedsbeckett.ac.uk/3309/1/The cytochrome P450 CYP6P4 is... · The cytochrome P450 CYP6P4 is responsible for the high pyrethroid

The cytochrome P450 - Leeds Beckett Universityeprints.leedsbeckett.ac.uk/3309/1/The cytochrome P450 CYP6P4 is... · The cytochrome P450 CYP6P4 is responsible for the high pyrethroid

Cytochrome P450 derived eicosanoids

Cytochrome P450 derived eicosanoids

...Cytochrome P450 ÿYt±) Cytochrome b o Cytochrome Cytochrome ("11*H Cytochrome Cytochrome RH +NADPH + +02. ROH + NADP* + H20 (P450) y —A (Cytochrome*) fiž P450& Cytochrome F

...Cytochrome P450 ÿYt±) Cytochrome b o Cytochrome Cytochrome ("11*H Cytochrome Cytochrome RH +NADPH + +02. ROH + NADP* + H20 (P450) y —A (Cytochrome*) fiž P450& Cytochrome F

Gianfranco Gilardi, FRSC · Gilardi, G. “Human cytochrome P450 3A4 as a biocatalyst: Effects of the engineered linker in modulation of coupling efficiency in 3A4-BMR chimeras”

Gianfranco Gilardi, FRSC · Gilardi, G. “Human cytochrome P450 3A4 as a biocatalyst: Effects of the engineered linker in modulation of coupling efficiency in 3A4-BMR chimeras”

Overexpression of the cytochrome P450 cyp71av1 cpr content ... · Overexpression of the cytochrome P450 monooxygenase (cyp71av1) and cytochrome P450 reductase ... while CPR is a redox

Overexpression of the cytochrome P450 cyp71av1 cpr content ... · Overexpression of the cytochrome P450 monooxygenase (cyp71av1) and cytochrome P450 reductase ... while CPR is a redox

Inactivation of Human Cytochrome P450 3A4 and 3A5 by · cytochrome P450 enzymes (CYP) (Ferrari and Dusi, 2012). N-desbutyl dronedarone (NDBD) (Fig. 1C), the main metab-olite formed

Inactivation of Human Cytochrome P450 3A4 and 3A5 by · cytochrome P450 enzymes (CYP) (Ferrari and Dusi, 2012). N-desbutyl dronedarone (NDBD) (Fig. 1C), the main metab-olite formed

The Cytochrome P450 gene CYP6P12 confers pyrethroid ...archive.lstmed.ac.uk/5851/1/Sci_Rep_6_24707_The Cytochrome P45… · The P450 transcript Aalb_oocyte_ GH79BIP02GBWB9, with the

The Cytochrome P450 gene CYP6P12 confers pyrethroid ...archive.lstmed.ac.uk/5851/1/Sci_Rep_6_24707_The Cytochrome P45… · The P450 transcript Aalb_oocyte_ GH79BIP02GBWB9, with the

Ligand Binding to Cytochrome P450 3A4 in Phospholipid Bilayer ...

Ligand Binding to Cytochrome P450 3A4 in Phospholipid Bilayer ...

MOL #103721molpharm.aspetjournals.org/content/molpharm/early/2016/... · MOL #103721 1 N-heterocyclic carbene capture by cytochrome P450 3A4 Gareth K. Jennings, Caroline M. Ritchie,

MOL #103721molpharm.aspetjournals.org/content/molpharm/early/2016/... · MOL #103721 1 N-heterocyclic carbene capture by cytochrome P450 3A4 Gareth K. Jennings, Caroline M. Ritchie,

WARNINGS AND PRECAUTIONS - Food and Drug Administration€¦ · 5.11 Drug Interactions with Strong Cytochrome P450 3A4 . Inhibitors 5.12 Eosinophilic Conditions and Churg -Strauss

WARNINGS AND PRECAUTIONS - Food and Drug Administration€¦ · 5.11 Drug Interactions with Strong Cytochrome P450 3A4 . Inhibitors 5.12 Eosinophilic Conditions and Churg -Strauss

Directed Evolution of Cytochrome P450 CYP102A2 from Bacillus …globalsciencebooks.info/Online/GSBOnline/images/2010/DBPBMB_4(… · Cytochrome P450 BM-3 (CYP102A1 or CYP102 or P450

Directed Evolution of Cytochrome P450 CYP102A2 from Bacillus …globalsciencebooks.info/Online/GSBOnline/images/2010/DBPBMB_4(… · Cytochrome P450 BM-3 (CYP102A1 or CYP102 or P450

PHARMACOGENETICS AND CANINE CYTOCHROME P450 POLYMORPHISMSlib.ugent.be/fulltxt/RUG01/002/216/035/RUG01-002216035_2015_0001... · PHARMACOGENETICS AND CANINE CYTOCHROME P450 POLYMORPHISMS

PHARMACOGENETICS AND CANINE CYTOCHROME P450 POLYMORPHISMSlib.ugent.be/fulltxt/RUG01/002/216/035/RUG01-002216035_2015_0001... · PHARMACOGENETICS AND CANINE CYTOCHROME P450 POLYMORPHISMS

Inactivation of Human Cytochrome P450 3A4 and 3A5 bymolpharm.aspetjournals.org/content/molpharm/89/1/1.full.pdf · discovery of glutathione adducts derived from ... toxicity and clinical

Inactivation of Human Cytochrome P450 3A4 and 3A5 bymolpharm.aspetjournals.org/content/molpharm/89/1/1.full.pdf · discovery of glutathione adducts derived from ... toxicity and clinical

Pharmacogenomics of human P450 oxidoreductaseboris.unibe.ch/65307/1/fphar-05-00103.pdf · Cytochrome P450 oxidoreductase (POR) supports reactions of microsomal cytochrome P450 which

Pharmacogenomics of human P450 oxidoreductaseboris.unibe.ch/65307/1/fphar-05-00103.pdf · Cytochrome P450 oxidoreductase (POR) supports reactions of microsomal cytochrome P450 which

Cytochrome P450 (Cyp450)

Cytochrome P450 (Cyp450)

4.11.Drug Metabolism Cytochrome P450

4.11.Drug Metabolism Cytochrome P450