Drugs ‘n’ stuffCogs 174

Winter 2012

Mike Datko

Correlation between signal in different brain regions?

???

“Functional connectivity”

BOLD signal(blood flow)

Anticorrelations?

Default Mode Network

a.k.a. Resting State Network

Looked at interaction between MDMA and THC in 3 measures of neurotoxicity

•Microglia activation•Astrocyte activation•Reduction in tyrosine hydroxylase

In room temperature vs. warm temperature

LinksCarl Sagan's pro-marijuana letter:http://marijuana-uses.com/mr-x

Huge forum site about everything drug-related:http://www.bluelight.ru/vb/

http://www.bluelight.ru/vb/threads/317270-Brain-Imaging-amp-Psychoactives-(fMRI-PET-EEG-MRI-SPECT-DOT-fNIR-MEG-etc.)

Mouse Party:http://learn.genetics.utah.edu/content/addiction/drugs/index.html

Massive drug information website. Information about pharmacological, cognitive, and behavioral effects, news articles, experience reports, and much more:http://www.erowid.org

Linkshttp://www.drugwarfacts.org/cms/

http://stopthedrugwar.org/

ethics of cognitive stimulants:http://thetechnologicalcitizen.com/?p=2444

Recent (March 13) debate hosted by Google on the war on drugs:http://www.youtube.com/watch?v=gSrN2zIRwN8

Bush Sr. and crack:http://www.metafilter.com/94969/The-Kid-Who-Sold-Crack-to-the-Presidenthttp://www.c-spanvideo.org/program/8921-1

"Just Say No” police/DARE music video from late 80's/early 90's. http://www.youtube.com/watch?v=mcxDPJ5a5oQ

Forum thread with links about issue of Marijuana legalization:http://www.metafilter.com/112959/Progress-Stalled

1994 Tobacco company executive testimony before congressional committee:http://www.youtube.com/watch?v=NC4f_yfuR34

LinksEffects of MDMA:

Post in forum thread about ecstasy, from an apparent expert in the field:http://ask.metafilter.com/128422/I-took-MDMA-for-the-first-time-and-have-some-questions#1835735

"Does Ecstasy cause brain damage?" Gigantic page from Erowid with a lot of studies cited. Dated 2001 so may need to be updated:http://www.erowid.org/chemicals/mdma/mdma_neurotoxicity1.shtml

Conclusions

What you should take away from this course:

Question what society and organizations tell you…know the facts.

Question your own biases…know the facts

Where do you get the facts? Science!

Timothy Leary may have said it best:

“Think for yourself, question authority”