Drug Study Hepatitis

DRUG STUDY

Medical Diagnosis: Drug induced Hepatitis 2o anti koch’s medicationCategory: I

Indication/contraindication

Mechanism of action Rationale for patient

Side effects / adverse effects

Nursing considerations

Generic name:Vitamin B-Complex with vitamin CBrand name:Vaneular tablet

Classification:Dietary supplement

Dosage:1 tablet

Frequency:Two times a day

Route:Per Orem

Date Ordered:June 16, 2010

Recommended dose: 27 years old-

Mild cases &

for

maintenance 1

-2 tab daily

Therapeutic level:

conditions eg malabsorption syndrome; radiation sickness; malnutrition or deficiency diseases; severe infections.

Transient diarrhea

Itching- and urticarcia

Anaphylactic shock

Increased uric acid levels, increased urinary calcium

Patient education: Instruct patient strict compliance of taking multivitamins and report side-effects

http://www.mims.com.ph/Page.aspx?menuid=companionhome&ID=1434







Generic name:

L-ornithine-L-

aspartate

Brand name:Hepa-Merz sachet

Classification:Cholelitholytics & Hepatic Protectors

Dosage:1 sachet dissolve with ½ glass of water

Frequency:Two times a day

Route:Per orem

Date Ordered:June 26,2010


1-2 sachets of Hepa-Merz 1-2 times daily

Therapeutic level:

Acute and

chronic liver

disease eg, liver

cirrhosis, fatty

liver, hepatitis

L-ornithine-L-aspartate stimulates ammonia detoxification by enhancing urea synthesis in the urea cycle. Additionally, it eliminates extrahepatic ammonia from the tissues.

Severe renal impairment

Monitor laboratory results such as liver function test, and

serum creatinine level exceeding 3 mg/100 mL

Dissolve content of the sachet with plenty of liquids










Generic name:Ursodeoxycholic acidBrand name:Ursofalk


Dosage:250 mg/cap

Frequency:Three times a day

Route:Per orem


Recommended dose: 27 years old- 300 mg b.i.d.

Therapeutic level:

Treatment of cholestatic liver disease.

Supress hepatic synthesis , biliary secretion and intestinal reabsorbing of cholesterol.

CNS: Anxiety, fatigue, depression

CV: chest pain, hypertension, peripheral edema.

Gallstone calcification

Administer with food intake

Be aware of too much intake of drug, diarrhea may occur

Urge patient to notify the physician immediately for signs of acute cholecytitis







Generic name:

Brand name:Essentiale Forte


Dosage:1 capsule


Route:Per orem



1-2 forte caps 3 times

a day for the

first 2 months

Therapeutic level:

Acute and Chronic Hepatitis.

Liver Damaged by

Toxins

It activates metabolic

function and supports

the energy balance of

the liver. It restores

enzyme functions and

promotes detoxification

of the liver. Neutral fats

and cholesterol are

transformed into

transportable forms and

led to their physiological

oxidation. Liver cell

regeneration is

stimulated and the bile

is stabilized.





Generic name:LactuloseBrand name:Duphalac

Classification:Ammonia reducer

Dosage:30 ml


Route:Per Orem



20 to 30 g (30 to 45 ml) P.O. t.i.d. or q.i.d.

Therapeutic level:

Prevention of hepatic encephalopathy

It makes the intestinal contents more acidic than blood. This prevent ammonia diffusion from the intestine into the blood, as occur in hepatic encephalopathy. The trapped ammonia ions and by lactulose laxative effect is expelled by the feces.

Gi: Abdominal cramping and distention, diarrhea and flatulence

Hypokalemia, hypovolemia, hypernatremia.

Monitor blood ammonia level, electrolytes level and signs of dehydration

Dilute the medication with water or take it with food

Inform patient to report any adverse reaction of the medication to the physician





Generic name:Potassium ChlorideBrand name:Kalium

Classification:Electrolytes

Dosage:

Frequency:For ever 6 hours

Route:



.

Therapeutic level:

Hypokalemia

Acts as the major cation in intracellular fluid, activating many enzymatic reactions that are essential for physiologic process, including nerve impulse transmission and cardiac and skeletal muscle contraction.Given to patient with drugs that causes hypokalemia such as lactulose

Acute dehydration

Addison’s disease

Hypersensitivityto potassium salt

Renal impairment

Arrhythmias

Hyperkalemia

Rash Ulceration Nasea and

vomiting

Administer oral potassium with or immediately after meals

Mix potassium chloride for oral solution in cold water, orange juice and stir it for 1 minute before administering

Regularly assess for signs of hypokalemia

Monitor for the serum creatinine, and urinary outputHealth education: teach ways on how to take potassium medication and take drugs after

Drug Study Hepatitis

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