Driving healthcare savingsThe EliA Calprotectin 2 test – helping rule out inflammatory bowel disease (IBD) correctly, the first time

Driving healthcare savingsEliA Calprotectin 2 test offers you:

The ability to correctly rule out more IBD, the first time6

By using a test with high NPV you can help your clinical customers rule out IBD correctly; helping, due to a low false positive rate, reduce the number of avoidable endoscopies and therefore leading to healthcare cost savings

A test optimised to save time and reduce laboratory costs

Due to the broad GI portfolio on Phadia Laboratory Systems, in one GI workflow you have the ability to test to identify or exclude: IBS, IBD, coeliac disease, wheat allergy and non-coeliac gluten sensitivity

The ability to introduce a dedicated instrument

Due to the small footprint of the Phadia 200* instrument you can test for EliA Calprotectin 2 wherever sample extraction takes place and receive collated results on the same network using Phadia Prime software

*Phadia 200 instrument is capable of performing over 700 different ImmunoCAP and EliA tests

REFERENCES1. Scherl EJ, et al. Gastroenterology and endoscopy new special edition. October 2013. Available from http://www.gastroendonews.com/download/UC_IBDgen0513_WM.pdf; last accessed January 2020. 2. Vavrika SR, et al. Inflamm Bowel Dis 2012;18:496-505. 3. Schoepfer AM, et al. Am J Gastroenterology 2013;108:1744-1753. 4. Furfaro F, et al. Outcomes of conservatively managed acute small bowel obstruction and predictors for subsequent surgery in Crohn’s disease. Poster No P187 on the 9th congress of ECCO, Copenhagen, Denmark, 2014. 5. Sabatino A, et al. Previous misdiagnosis and diagnostic delay in inflammatory bowel diseases. Poster No P118 on the 6th congress of ECCO, Dublin, Ireland, 2011. 6. Wulandari AA, Schulz J, Hartmann F, Dignass A, Stein J. Poster No 119 presented at 11th Congress of ECCO, Amsterdam, Netherlands, 2016 e 48. 7. Thermo Fisher Scientific. Internal Data on File. 8. EliA Calprotectin 2. Directions for Use.

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Reducing the number of avoidable endoscopies

A partner you can rely on to help simplify laboratory lifeOptimised workflow – supporting your lean approach

EliA Calprotectin 2 can help your clinical customers reduce healthcare costs

Early diagnosis in IBD is associated with improved patient outcomes

EliA Calprotectin 2 test and Phadia 200 instrument: made to measure together

Easily integrates into existing workflows

A fast and accurate test

Provides more flexibility to the laboratory routine

Saves costs

EliA Calprotectin 2 test can be performed at the same time as other EliA and ImmunoCAP™ serum tests

The optimised stool extraction buffer means that stool extracts are stable for three days at room temperature8

High measuring range for less dilution of highly positive samples

Routine stool extraction samplesare processed automatically

by Phadia™ instruments

Based on your lab volume of 1,000 and prevalence of 2%, this would mean: EliATM Calprotectin 2 correctly differentiates 105 additional patients (IBD and non-IBD patients) versus supplier 1 (746 vs. 641.5)

EliA Calprotectin 2 also reduces the number of false positive results by 104 versus supplier 1 (253.8 vs. 357.7) meaning 104 fewer avoidable endoscopies. A potential cost saving of €41,288 based on an average endoscopy cost of €397.

*Negative predictive value Performance of EliA Calprotectin 2 test and one other supplier in 99 symptomatic IBD patients and 83 controls with functional bowel disease6

35% of IBD patients are incorrectly diagnosed with irritable bowel syndrome (IBS) first – the average time to diagnosis of Crohn’s disease (CrD) is 18 months1,2

Early diagnosis is associated with:

Increased treatment success2,3

Reduced risk of surgery in CrD3,4

Fewer relapses in CrD3,5

Capable of performing over 700 different ImmunoCAP and EliA tests

Define test menus for your customers’ unique clinical needs

Reduce outsourcing of tests to other labs with an automated instrument designed for small spaces

Phadia Prime software integrates all in one network3

Use a dedicated system for your stool samples1 456

Wherever the sample extraction takes place, you can put Phadia 200 instrument there2

100%

0%

99% 95.9% 93.1%

63.5%

74.1%

98.4%

EliA Calprotectin 2 Supplier 1

Sensitivity Specificity NPV*