Dr Caroline Barelle MBA Giving birth to a biotech........ where’s the pain relief ?!
-
Upload
cameron-brooks -
Category
Documents
-
view
220 -
download
3
Transcript of Dr Caroline Barelle MBA Giving birth to a biotech........ where’s the pain relief ?!
![Page 1: Dr Caroline Barelle MBA Giving birth to a biotech........ where’s the pain relief ?!](https://reader036.fdocuments.us/reader036/viewer/2022062802/56649e885503460f94b8c546/html5/thumbnails/1.jpg)
Dr Caroline Barelle MBA
Giving birth to a biotech........where’s
the pain relief ?!
![Page 2: Dr Caroline Barelle MBA Giving birth to a biotech........ where’s the pain relief ?!](https://reader036.fdocuments.us/reader036/viewer/2022062802/56649e885503460f94b8c546/html5/thumbnails/2.jpg)
University
Fibrinolysis - PhD
BSc Biochem
![Page 3: Dr Caroline Barelle MBA Giving birth to a biotech........ where’s the pain relief ?!](https://reader036.fdocuments.us/reader036/viewer/2022062802/56649e885503460f94b8c546/html5/thumbnails/3.jpg)
University
Academia
Medical mycology
![Page 4: Dr Caroline Barelle MBA Giving birth to a biotech........ where’s the pain relief ?!](https://reader036.fdocuments.us/reader036/viewer/2022062802/56649e885503460f94b8c546/html5/thumbnails/4.jpg)
University
Academia
PI
![Page 5: Dr Caroline Barelle MBA Giving birth to a biotech........ where’s the pain relief ?!](https://reader036.fdocuments.us/reader036/viewer/2022062802/56649e885503460f94b8c546/html5/thumbnails/5.jpg)
University
Biotech
Academia
![Page 6: Dr Caroline Barelle MBA Giving birth to a biotech........ where’s the pain relief ?!](https://reader036.fdocuments.us/reader036/viewer/2022062802/56649e885503460f94b8c546/html5/thumbnails/6.jpg)
Stop Press………October 2007 Wyeth acquires Haptogen
![Page 7: Dr Caroline Barelle MBA Giving birth to a biotech........ where’s the pain relief ?!](https://reader036.fdocuments.us/reader036/viewer/2022062802/56649e885503460f94b8c546/html5/thumbnails/7.jpg)
From the ocean to the clinic……………..
7
![Page 8: Dr Caroline Barelle MBA Giving birth to a biotech........ where’s the pain relief ?!](https://reader036.fdocuments.us/reader036/viewer/2022062802/56649e885503460f94b8c546/html5/thumbnails/8.jpg)
University
Biotech
Pharma
Academia
![Page 9: Dr Caroline Barelle MBA Giving birth to a biotech........ where’s the pain relief ?!](https://reader036.fdocuments.us/reader036/viewer/2022062802/56649e885503460f94b8c546/html5/thumbnails/9.jpg)
A shot from the blue………………..
9
![Page 10: Dr Caroline Barelle MBA Giving birth to a biotech........ where’s the pain relief ?!](https://reader036.fdocuments.us/reader036/viewer/2022062802/56649e885503460f94b8c546/html5/thumbnails/10.jpg)
University
Biotech
Pharma
The biggest Pharma
Academia
![Page 11: Dr Caroline Barelle MBA Giving birth to a biotech........ where’s the pain relief ?!](https://reader036.fdocuments.us/reader036/viewer/2022062802/56649e885503460f94b8c546/html5/thumbnails/11.jpg)
University
Biotech
Pharma
The biggest Pharma
Academia
?
![Page 12: Dr Caroline Barelle MBA Giving birth to a biotech........ where’s the pain relief ?!](https://reader036.fdocuments.us/reader036/viewer/2022062802/56649e885503460f94b8c546/html5/thumbnails/12.jpg)
University
Biotech
Pharma
The biggest Pharma
Academia
Asset portfolio
IP/domains
![Page 13: Dr Caroline Barelle MBA Giving birth to a biotech........ where’s the pain relief ?!](https://reader036.fdocuments.us/reader036/viewer/2022062802/56649e885503460f94b8c546/html5/thumbnails/13.jpg)
University
Biotech
Pharma
The biggest Pharma
Academia
Investment
![Page 14: Dr Caroline Barelle MBA Giving birth to a biotech........ where’s the pain relief ?!](https://reader036.fdocuments.us/reader036/viewer/2022062802/56649e885503460f94b8c546/html5/thumbnails/14.jpg)
Pushmi-Pullyu/Need-Desire………………
![Page 15: Dr Caroline Barelle MBA Giving birth to a biotech........ where’s the pain relief ?!](https://reader036.fdocuments.us/reader036/viewer/2022062802/56649e885503460f94b8c546/html5/thumbnails/15.jpg)
The Business of Biotech………………
15
Takes a long time and a lot of money
![Page 16: Dr Caroline Barelle MBA Giving birth to a biotech........ where’s the pain relief ?!](https://reader036.fdocuments.us/reader036/viewer/2022062802/56649e885503460f94b8c546/html5/thumbnails/16.jpg)
The Model………………
Medical devices,
Clinical Diagnostics,
Lower risk, lower return
Potential for early revenues
Exit often trade-sale
Drug discovery
High risk
Makes nothing, sells nothing
99% chance of failure
Consumes loads of cash
Returns are staggering if successful
![Page 17: Dr Caroline Barelle MBA Giving birth to a biotech........ where’s the pain relief ?!](https://reader036.fdocuments.us/reader036/viewer/2022062802/56649e885503460f94b8c546/html5/thumbnails/17.jpg)
The Model………………
Medical devices,
Clinical Diagnostics,
Lower risk, lower return
Potential for early revenues
Exit often trade-sale
Drug discovery
High risk
Makes nothing, sells nothing
99% chance of failure
Consumes loads of cash
Returns are staggering if successful
![Page 18: Dr Caroline Barelle MBA Giving birth to a biotech........ where’s the pain relief ?!](https://reader036.fdocuments.us/reader036/viewer/2022062802/56649e885503460f94b8c546/html5/thumbnails/18.jpg)
Money, money, money………………..
Seed Series A Series B Series C
![Page 19: Dr Caroline Barelle MBA Giving birth to a biotech........ where’s the pain relief ?!](https://reader036.fdocuments.us/reader036/viewer/2022062802/56649e885503460f94b8c546/html5/thumbnails/19.jpg)
• IP from University/parent body• Technology validation – “Proof of
Concept”• Commercial prototype and early pre –
clinical trials.
Idea generation
and validation
• Technology platform and IP broadening• Management team & Scientific group
hiring• Partnership and building company
infrastructure
Early Stage – Start up
• Continue with clinical development (Launching of product) and prepare exit (Eg., IPO)
• Aim for cash flow, break – even and lastly profit
Late stage – Expansion/public offering
The Process………………
![Page 20: Dr Caroline Barelle MBA Giving birth to a biotech........ where’s the pain relief ?!](https://reader036.fdocuments.us/reader036/viewer/2022062802/56649e885503460f94b8c546/html5/thumbnails/20.jpg)
The Conception………………..
Asset portfolio
Proposals
Pre-commercialisation cash
Build team and company value
![Page 21: Dr Caroline Barelle MBA Giving birth to a biotech........ where’s the pain relief ?!](https://reader036.fdocuments.us/reader036/viewer/2022062802/56649e885503460f94b8c546/html5/thumbnails/21.jpg)
The Development………………..
Science
Commercial
Investor ready
Value proposition
BP
IP
InvestorsConsultants
Milestones
CROs
Reporting
Meetings
Customers
Secure seed/series A
Value build
Conferences
Collaborations
![Page 22: Dr Caroline Barelle MBA Giving birth to a biotech........ where’s the pain relief ?!](https://reader036.fdocuments.us/reader036/viewer/2022062802/56649e885503460f94b8c546/html5/thumbnails/22.jpg)
The Labour………………..
22
• Lead the Science
• Operations
• Business Development
• Commercialisation/Corporate
• Alliance management
• Reports
• Due Diligence
• IP
• Papers
• Conferences
• BioPartnering
• Budget
![Page 23: Dr Caroline Barelle MBA Giving birth to a biotech........ where’s the pain relief ?!](https://reader036.fdocuments.us/reader036/viewer/2022062802/56649e885503460f94b8c546/html5/thumbnails/23.jpg)
The Birth………………..
23
• Articles of association
• Shareholding
• Legal
• Employee contracts
• Facilities
• Finance
• IP
• Consultants
• SAB
• Chair
• Directors
• NEDs
• Marketing
• Website
• HR
• Organizational Development
• Press
The next tranche of cash!
![Page 24: Dr Caroline Barelle MBA Giving birth to a biotech........ where’s the pain relief ?!](https://reader036.fdocuments.us/reader036/viewer/2022062802/56649e885503460f94b8c546/html5/thumbnails/24.jpg)
The Pain Relief………………..
24
• A good team
• External support
• Be realistic
• Enjoy
![Page 25: Dr Caroline Barelle MBA Giving birth to a biotech........ where’s the pain relief ?!](https://reader036.fdocuments.us/reader036/viewer/2022062802/56649e885503460f94b8c546/html5/thumbnails/25.jpg)
25Questions??