1

Dori L. Borjesson DVM, PhD, Dipl. ACVP (Clinical Pathology) Professor and Chair, Vet Med: Pathology, Microbiology, Immunology School of Veterinary Medicine University of California Davis, CA 95616 EDUCATION: PhD 2002 University of California, Davis. Comparative Pathology. Dissertation Title: Host Cell-Pathogen Interactions and Infection Kinetics of

Human Granulocytic Ehrlichiosis in a Mouse Model DVM 1995 University of California, Davis, CA Graduated Phi Zeta MPVM 1995 University of California, Davis, CA Emphasis: Epidemiology/ Wildlife Health BA 1988 The Colorado College, Colorado Springs, CO Major: Biology, Graduated with distinction

BOARD CERTIFICATION: Diplomate, American College Veterinary Pathologists. Specialty Boards in Clinical Pathology, 1999. PROFESSIONAL POSITIONS: 1995-1996 Associate Veterinarian (Small Animal), Animal Hospital of Salinas, Salinas, CA. 1996-1999 Resident in Clinical Pathology, University of California, Davis. 1998-2001 Relief Clinical Pathologist, IDEXX Laboratory, Inc., West Sacramento, CA. 1999-2002 NIH Postdoctoral Fellow (PhD candidate), University of California, Davis.

T32 Comparative Medical Science Program. Major Professor: Stephen Barthold, DVM, PhD, Dipl. ACVP

3/2002-9/2006 Assistant Professor, Dept of Veterinary Population Medicine, College of Veterinary

Medicine, University of Minnesota, St. Paul, MN 4/2002- 9/2006 Division Head, University Veterinary Medical Center Clinical Laboratories, College of

Veterinary Medicine, University of Minnesota, St. Paul, MN 4/2002- 9/2006 Director of Clinical Laboratories, University Veterinary Medical Center, College of

Veterinary Medicine, University of Minnesota, St. Paul, MN 3/2003- 9/2006 Clinical Pathology Section Head, Veterinary Diagnostic Laboratory, University of

Minnesota, St. Paul, MN

2

2006-2011 Associate Professor, Dept of Pathology, Microbiology, Immunology, School of Veterinary Medicine, University of California, Davis, CA

2008-2009 Service Chief, Clinical Pathology Labs, School of Veterinary Medicine, University of

California, Davis, CA 2009-2010 Interim Department Chair, Pathology, Microbiology, Immunology, School of Veterinary

Medicine, University of California, Davis, CA 2010-present Director, Clinical Regenerative Medicine Laboratory, School of Veterinary Medicine,

University of California, Davis, CA 2015-2019 Director, Veterinary Institute for Regenerative Cures, School of Veterinary Medicine,

University of California, Davis, CA 2012-present Full Professor, Dept of Pathology, Microbiology, Immunology, School of Veterinary

Medicine, University of California, Davis, CA 2013-present Department Chair, Dept of Pathology, Microbiology, Immunology, School of Veterinary

Medicine, University of California, Davis, CA LEADERSHIP TRAINING: 2012 UC Davis Department Chairs Leadership Program. University of California, UC Davis

Extension, Davis, CA 2013-2014 AAVMC Leadership Academy TEACHING EXPERIENCE: DVM Professional Curriculum

Year Role Course Locatio Hours/yr Instruction Type 1996-1999 Instructor Clinical Hematology UCD 15 Discussion/Lab 1996-1999 Instructor Cytology/ Clinical Chemistry UCD 12 Discussion/Lab 1996-1999 Instructor Senior Rotation in Clinical Pathology UCD 120 Small groups 2002-2006 Director Senior Rotation in Laboratory Medicine UMN 100 Small groups 2002-2005 Instructor Veterinary Pathology (Inflammation) UMN 12 Lecture/Lab 2002-2005 Instructor Multisystemic Disease (Hematology and

Coagulation) UMN 6 Lecture

2005-2006 Instructor Veterinary Clinical Pathology (WBC, platelets, bone marrow, hemic neoplasia)

UMN 12 Lecture/Lab

2006-2007 Instructor Veterinary Hematology (RBC structure and function

UCD 9 Lecture/Lab

2006-2012 Instructor Senior Rotation in Clinical Pathology UCD 120 Small groups 2007-2012 Director Veterinary Clinical Pathology UCD 75 Lecture/Labs 2011-2013 Block Leader Clinical Foundations UCD 15 Lecture/Labs 2012-present Instructor Hematology/ Coagulation UCD 12 Lecture/Labs 2012-present Instructor Oncology UCD 2 Discussion 2012-present Instructor Musculoskeletal UCD 2 Discussion 2012-present Instructor Clinical Foundations UCD 8 Discussions 2012-present Instructor Senior Rotation in Clinical Pathology UCD 6 Small groups

3

Resident Curriculum Year Role Course Location Hours/yr Instruction Type 2002-2006 Director Clinical Pathology Seminar UMN 16 Rounds 2006-present Director Weekly Cytology rounds UCD 48 Rounds 2006-present Instructor Weekly journal club/ Topical rounds UCD 48 Rounds 2006-2009 Instructor Resident Board Preparation-bone

marrow and hemic neoplasia UCD 2 Rounds

Graduate Curriculum Year Role Course Location Hours/yr Instruction Type 2002-2006 Instructor Ethical Conduct of Animal Research UMN 1 Lecture 2004-2006 Instructor Mechanisms of Animal Health and

Disease (Innate Immunity) UMN 1 Lecture

2012 Instructor Cellular Basis of Disease UCD 2 Lecture 2013-2015 Director Integrative Pathobiology I UCD 15 Lecture/ Journal Club 2013-present Instructor Integrative Pathobiology II UCD 10 Lecture/Journal Club 2013-present Instructor Clinical Immunology UCD 2 Lecture 2015-present Director Research Foundations UCD 10 Lecture Other Curriculum

STUDENTS/RESIDENTS MENTORED: Residents: Dr. Jennifer Brazzell, clinical pathology resident, passed boards 2005 Dr. Inese Berzina, clinical pathology resident, passed European Boards in 2009 Dr. Jed Overmann, clinical pathology resident, passed boards 2007 Dr. Shanon Zabolotzky, clinical pathology resident, passed boards in 2008 Dr. Keith DeJong, clinical pathology resident, passed boards in 2010 Dr. Joy Atkin, clinical pathology resident, sitting boards in 2009 Dr. Joanne Hodges, clinical pathology resident, passed boards in 2010 Dr. Amir Kol, clinical pathology resident, passed boards in 2011 Dr. Connie Wu, clinical pathology resident, passed boards in 2014 Dr. Andrew Burton, clinical pathology resident, passed boards in 2014 Dr. Yemi Adedeji, clinical pathology resident, passed boards in 2015 Dr. Diana Schwartz, clinical pathology resident, passed boards in 2017 Dr. Noa Safra, clinical pathology resident, passed boards in 2018 Dr. Demi Vasilatis, 3rd year clinical pathology resident, sitting boards in 2020 Dr. Flavio Alonso, 2nd year clinical pathology resident, sitting boards in 2021

Year Role Course Location Hours/yr Instruction Type 2018-present Director Veterinarian for a Day: Blood and Discovery

for Davis Senior High School Students UCD 2 Lab

2019-present Director VetMed Exploration Academy: Blood and Discovery for URM and first generation students

UCD 3 Lab

4

Graduate students: Dr. Melissa Blauvelt, MS student, primary mentor, MS received 2004 (University of MN) Zhenya Ni, thesis committee member, PhD received 2008 (University of MN) Dr. Jennifer Granick, MS, graduate advisor, MS received 2008 (University of MN) Dr. Jennifer Johns, PhD student, primary PhD mentor (UC Davis), 2006-2011 (PhD received) Elizabeth Schuh, MS student, graduate advisor, 2007-2008 (UC Davis) Dr. Jennifer Granick, PhD student, primary PhD mentor, (UC Davis), 2008-2012 (PhD received) Danielle Carrade, PhD student, primary PhD mentor, (UC Davis), 2008-2012 (PhD received) Rhiannon Davies, MS student, (Comparative Pathology, UCD), committee member, 2007-2008 Hiromi Inoue, MPVM student (UCD), committee member, 2008-2009, MPVM received 2009 Robert Gower, PhD student (Biomedical Engineering, UCD), committee member, PhD received 2010. Mary Saunders, PhD student (Comparative Pathology, UCD), committee member, PhD received 2013. David Olivos, PhD student (Comparative Pathology, UCD), committee member, PhD received 2013. Astra Chang, PhD student (Comparative Pathology, UCD), committee member, PhD received 2013. Dr. Barbara Gericota, PhD student (Comparative Pathology, UCD), committee member, PhD received 2014. Soraya Foutahi, PhD student (Comparative Pathology, UCD), committee member, PhD received 2014. Dr. Amir Kol, PhD student (Comparative Pathology, UCD), primary PhD mentor, PhD received 2015. Dr. Dawn Kingsbury, PhD student (Comparative Pathology, UCD), committee member, PhD received 2015. Julie Beegle, PhD student (Comparative Pathology, UCD), committee member, PhD received 2015. Matt Mullin, MS student (Animal Sciences, UCD), committee member, 2014-2016 Kaitlin Clark, MS student (Stem Cell Biology, Sacramento State), primary mentor. 2014-2016 Ash Sundaram, PhD student (VSTP program; Integrative Pathobiology, UCD), primary PhD mentor. 2016-2017.

NIH 5T32OD010931-11 Program (Yearlong Exposure to Advanced Research (YEAR) Program for Vet Students

Dr. Nopmanee Taechangam (Integrative Pathobiology, UCD), MS student (Fulbright scholar), Primary PI. 2017-2019 Dr. Nopmanee Taechangam (Integrative Pathobiology, UCD), PhD student, Primary PI. 2019-present Ellie Harness (Animal Biology, UCD), PhD student, dissertation committee member. 2015- Maryam Moshref (Integrative Pathobiology, UCD), PhD student, dissertation committee member. 2015- Dr. Laura Cagle (Integrative Pathobiology, UCD), PhD student, dissertation committee member, 2016- Research students: Kelly O’Donnell, Hodson Summer Research Internship Program (2003), St. Johns College, Annapolis, MD.

Platelet-neutrophil interactions during Anaplasma phagocytophilum infection. Jamie Chou, senior thesis advisor, School of Agriculture, University of Minnesota (2004-2005).

Development of a PCR for the detection of Borrelia burgdorferi in canine formalin-fixed tissues. Mary McKie, Summer Scholars Program, College of Veterinary Medicine, University of Minnesota (2005), Mechanisms of platelet dysfunction associated with Anaplasma phagocytophilum infection. Alyssa Bernanke, Hodson Summer Research Internship Program (2009), St. Johns College, Annapolis, MD. Point-of-care cell therapies Kristin Trott, STAR student, Summer 2007 (UC Davis) Kaitlin Clark, UC Davis, B.S. in psychobiology UC, Davis (2010). 2009-2011

Equine Stem cell phenotype and proliferation in serum-free media Salpi Shahbenderian, BS, 2012-2013, research student from ABI Research Based Major in Animal Biology Canine MSCs in serum-free media Jessica Gillette, BS, STAR student, summer 2012, equine stem cell project Equine MSC modulation of lymphocyte phenotype in vivo Zoe Williams, BS, Student volunteer, 2012-2013. Andrea Bledsoe, BS, STAR student. Summer 2014.

5

Equine wound healing project Monica Nordstrom, pre-vet student, UC San Diego. Summer 2014.

Stem cells for canine inflammatory bowel disease Arik Davidyan, BS student, UC Davis. 2014-2015.

Stem cells for canine inflammatory bowel disease Rushdi Kayed. Undergraduate student, UC Davis. 10/14- 12/15.

Gene expression in equine wounds Lyndsey Marsh. Undergraduate student, UC Davis. 3/15- present. Equine biomarkers for foot diseases. Evelyn Bulkeley, BS, STAR student, NIH Merial, UCD. Summer 2015.

Feline chronic gingivostomatitis project Arash Sarlati, BS, Summer DVM student, UCD. Summer 2015. Canine MSC transfection project Seldy Nelson, BS, 2015-2017, research student from ABI Research Based Major in Animal Biology Equine Recurrent Uveitis Ayswarya Sundaram (Ash), BS, STAR student, NIH Merial, UCD. Summer 2016. Mesenchymal stem cells and Feline CD8+ T cells Kathryn Ann Beswetherick, BS, STAR student, UCD. Summer 2016. Canine MSC transfection project Laurel Saldinger, BS, STAR student, UCD. Summer 2017 and Summer 2018 Equine recurrent uveitis project Anthony Diamino, BS, UCD. Fall, 2018 Feline chronic ginvivostomatitis study Giovani Pimental (high school student), Summer 2018. Postdoctoral research fellows: Laurie Bohannon, DVM. UC Davis. 2010-2011. Effects of ancillary products on equine MSC function Scott Haskell, DVM, PhD, (visiting scholar). 2011. GI microbe-MSC interaction Josh A Wood, PhD. Tissue Engineering, UC Davis. 2013-2014. Jamie Textor, DVM, PhD. UC Davis. 2013-2014. Equine wound healing using MSCs Emily Mills Ko, PhD. Immunology, UC Davis. 11/2014 - 3/2016. Fabio A. Aristizabal, DVM, equine surgeon. 7/2015- 4/2016 Pablo Espinosa Mur, DVM, equine surgeon. 8/1/16-12/31/17 Visiting scholars Dr. Danielle Barberini DVM, PhD candidate, visiting scholar from Brazil, FAPESP program, 3/15-12/15.

Mesenchymal stem cells for treatment of neurological diseases in horses Dr. Rogerio Martins Amorim DVM, PhD (neurologist), visiting scholar (sabbatical) from Brazil, FAPESP

program, 8/1/16- 7/31/17. Mesenchymal stem cells for treatment of inflammatory brain disease in dogs. Dr. Takashi Taguchi DVM. Masters candidate, visiting scholar from Western University, 6/2017-8/2017.

Influence of Donor’s Age on Canine Adipose-Derived Mesenchymal Stem Cells. PROFESSIONAL MEMBERSHIPS: American College of Veterinary Pathology (ACVP) American Society for Veterinary Clinical Pathology (ASVCP) International Society for Cellular Therapy (ISCT) North American Veterinary Regenerative Medicine Association (NAVRMA)

6

IN THE NEWS AND OUTREACH: 2008 http://www.bizjournals.com/sacramento/stories/2008/03/10/story2.html 2009 http://www.theaggie.org/2009/06/03/uc-davis-veterinary-school-opens-new-stateoftheart-stem-

cell-lab/ 2010 http://www.thehorse.com/articles/25156/regenerative-medicine-conference-attracts-vets-

researchers 2012 http://www.bizjournals.com/sacramento/print-edition/2012/07/20/job-growth-from-stem-cell-

grants.html 2013 http://www.nature.com/news/stem-cells-boom-in-vet-clinics-1.12765 2014 http://www.aahanet.org/blog/NewStat/post/2014/07/31/790914/Presenters-voice-optimism-for-

the-future-of-veterinary-stem-cell-therapy-at-AVMA-convention.aspx 2014 http://consciouscat.net/2014/04/14/stem-cell-therapy-helps-cat-stomatitis/ 2014 http://giving.ucdavis.edu/impacts-of-giving/campaign-gala.html 2015 http://veterinarynews.dvm360.com/print/426406?page=full (Cutting Edge Stem Cell Cures) 2015 http://www.healthline.com/health-news/medical-researchers-suggest-fewer-mice-more-cats-and-

dogs-100715 2015 http://medicalxpress.com/news/2015-10-companion-animal-patients-aid-scientists.html 2016 http://www.dailydemocrat.com/science/20160201/cat-stem-cell-therapy-gives-humans-hope 2016 https://theaggie.org/2016/02/10/httpstheaggie-org20160209uc-davis-researco-human-medicine/ 2016 http://www.horse-canada.com/horse-news/inaugural-equine-world-stem-cell-summit/ 2017 http://www.sacbee.com/news/local/health-and-medicine/article169277882.html;

https://www.ucdavis.edu/news/stem-cell-treatment-children-spina-bifida-helps-dogs-first/; https://www.technologynetworks.com/cell-science/news/stem-cell-treatment-helps-puppies-with-spina-bifida-291374

http://veterinarynews.dvm360.com/stem-cell-treatment-helps-dogs-with-spina-bifida-approach-could-be-used-with-children

2018 http://www.latimes.com/la-me-uc-davis-vet-hospital-20180107-htmlstory.html https://www.thedailybeast.com/cats-and-dogs-might-help-figure-out-human-diseases?ref=home https://theaggie.org/2018/02/20/uc-davis-unique-method-treat-humans-pets/ http://www.americanveterinarian.com/news/feline-mesenchymal-stem-cells-whats-known-and-

whats-possible https://www.purinaproclub.com/sites/g/files/auxxlc346/files/2018-06/CatUpdate_Sumr2018.pdf PROFESSIONAL ACTIVITIES: Ad hoc manuscript reviewer: 2002- 2010

J. Dental Research, Vet. Clinical Pathology, Blood, J. Zoo and Wildlife Med., JVIM, AJVR, JAVMA, Leukemia Lymphoma, J. Parasitology, Equine Vet. Education, J. Feline Med and Surg.

2010-present Vet. Clin. Path., J. Feline Med and Surg., Comparative Immunology, Microbiology and Infectious Diseases, Recent Patents on Regenerative Medicine, Vet. Dermatology, J. Equine Vet. Science, Stem Cells, AJVR, JAVMA, Stem Cell Development, Cytotherapy, Cellular & Molecular Immunology, Tissue Engineering, Peer J, Future Medicine, Stem Cell Research and Therapy, BMC Vet. Research, Stem Cell Translational Medicine, J. Tissue Engineering and Regen. Med., Stem cell Reports, Veterinary Ophthalmology, J. Orthopedic Research, Vet Immunology Immunopathology

Grant reviewer: 2004, 2012 Ad hoc RO1 grant reviewer Infectious Diseases and Microbiology IRG panel, NIH. 2009 Grant Reviewer for Canine Health Foundation

7

2009-2013 Center for Companion Animal Health Scientific Advisory Committee 2011-2013 Center for Equine Health Scientific Review Board 2014-2016 GSSP, STAR and REACH student fellowship grant reviews, School of Veterinary

Medicine, UC Davis 2016 Ad hoc grant review, National Science Center, Poland 2019 Ad hoc grant review, Johnson Cancer Research Center, Kansas State University Search Committee Service: 2003 Clinical Pathology Faculty Search Committee, College of Veterinary Medicine, University of

Minnesota (Member) 2008 Clinical Pathology Faculty Search Committee, School of Veterinary Medicine, UC Davis (Chair) 2008 Health Sciences Assistant Clinical Professor-Anatomic Pathology Faculty Position, UC Davis

(Member) 2011 Anatomic Pathology Faculty Search Committee, School of Veterinary Medicine, UC Davis (Chair) 2014 Center for Comparative Medicine Faculty Search Committee (2 faculty hires) (Co-Chair) 2017 Center for Comparative Medicine Director Search Committee (Co-Chair) Committee Service (Department, School): 2002-2006 Curriculum & Education Policy Committee, College of Veterinary Medicine, University of

Minnesota (Member) 2002-2006 University Veterinary Medical Center Clinical Management Committee, College of

Veterinary Medicine, University of Minnesota (Member) 2002-2006 Point of Care Testing Task Force, College of Veterinary Medicine, University of Minnesota

(Member) 2004 Behavioral Interview Committee, College of Veterinary Medicine, University of Minnesota

(Member) 2007 VMTH Next Generation Steering Committee, Veterinary Medical Teaching Hospital, UC

Davis (Member) 2007-2009 Pathology, Microbiology and Immunology Department Resources Committee, UC Davis

(Member) 2008 Awards Committee, School of Veterinary Medicine, UC Davis (Member) 2008-2010 Research Committee, School of Veterinary Medicine, UC Davis (Member) 2010 Telemedicine Committee, VMTH, UC Davis (Member) 2010-2011 Admissions Advisory Committee, SVM, UC Davis (Member) 2011-2014 Graduate Clinical Education Committee, SVM, UC Davis (Member) 2012-2017 SVM Strategic Planning Committee (Member and Champion) 2013-present Academic Council (Leadership Team), SVM, UC Davis (Member) 2015-2016 Communications Advisory Committee, SVM, UC Davis (Member) 2015 Multiple Mini Interviews (MMI) interviewer 2017-2018 SVM Strategic Planning Committee (Member) Graduate School/ Group Service: 2002-2006 Veterinary Medicine Graduate Program, College of Veterinary Medicine, University of

Minnesota (member) 2002-2006 Molecular Veterinary Biosciences Graduate Program, College of Veterinary Medicine,

University of Minnesota (member) 2011-2014 Chair of the Graduate Group in Comparative Pathology, University of California, Davis, CA. 2014-2017 Chair of Admissions, Graduate Group in Integrative Pathobiology (formerly Comparative

Pathology), University of California, Davis. 2018 MPVM Thesis reviewer, SVM, UC Davis 2019 Graduate Studies Fellowship Review Committee

8

National Service: 2008-2013 ASVCP Treasurer HONORS, SCHOLARSHIPS AND AWARDS: Zoetis Excellence in Research Award, 2014 CL Davis Student Scholarship Award, 2001 ASVCP Excellence in Scientific Presentation Award, 1997 Phi Zeta Veterinary Honor Society, 1995 Hanson-Welles Memorial Scholarship, 1994 Best research/ presentation award for undergraduate thesis research, 1990 Graduation with Distinction, The Colorado College, 1988 PATENT APPLICATIONS: 1. Use Of Mesenchymal Stem Cells For The Treatment Of Inflammation, PCT/US2014/051524. USA

non-provisional: US20160199414; European Union non-provisional: EP3041929A1; Canada non-provisional: CA2960268A1.

All exclusively licensed by VetCell Therapeutics 2. Biomarker to Predict Response to MSC Treatment for Oral Inflammation, PCT/US2014/055529 GRANTS FUNDED: Center for Companion Animal Health (CCAH: 2019-24-R) $5,000 Borjesson (PI)- 5% effort (resident mentor, Demi Vasilatis) 2019-2020 Utility of amikacin to dissociate platelet aggregates in dogs and cats Center for Companion Animal Health (CCAH: 2019-10-F) $15,000 Borjesson (PI)- 5% effort 2019-2020 Safety and Efficacy of Stem Cells for Canine Myasthenia Gravis Center for Companion Animal Health (CCAH: 2019-38-R) $5,000 Borjesson (PI)- 5% effort (resident mentor, Flavio Herberg) 2019-2020 Do dogs and cats have transudative chylous effusion? Shriners Hospitals for Children. Co-investigator (5% effort) (Wang, PI). $500,000 Stem Cell-based Treatment of Spina Bifida in a Naturally Occurring 2018- 2020 Disease Model NIH (NIAMS), R01 AR067821. Co-investigator (2% effort) (Athanasiou, PI). $1,868,448 Title: Self-assembling process in tissue engineering of articular cartilage. 2015-2020 Center for Companion Animal Health (CCAH: 2018-15-F) $15,000 Borjesson (PI)- 5% effort 2018-2019 Systemic immunomodulation by feline mesenchymal stem cells in cats with Chronic Gingivostomatitis Center for Companion Animal Health (CCAH: 2017-57-F) $15,000

9

Borjesson (PI)-5% effort 2018-2019 Stem Cell-Based Treatment of Spina Bifida in English Bulldogs Winn Feline Foundation (MT17-008), Co-PI (5% effort), Arzi (PI) $28,000 Early Intervention Using Autologous Adipose-Derived Mesenchymal Stem Cell 2017-2018 Therapy for Cats with Chronic Gingivostomatitis: A Randomized, Controlled and Blinded Study GRANTS PENDING: Winn Feline Foundation. Borjesson (PI), 5% effort $30,000 Defining stem cell-induced alterations in CD8+ T cells in cats with Chronic Gingivostomatitis Center for Equine Health. Borjesson (PI), 5% effort $30,000 Mitotherapy for osteoarthritis (OA) related synovitis treatment – a new tool for veterinary medicine. GRANTS COMPLETED: Winn Feline Foundation. Borjesson (PI), 5% effort $13,000 Exploring the mechanisms by which feline mesenchymal stem cells 2017-2018 downregulate T cell activation and proliferation. VIRC Pilot Grant Program. PI (5% effort). $19,000 Deciphering feline stem cell interactions with CD8+ T cells 2017-2018 Center for Companion Animal Health (CCAH) and Center Equine Health (CEH), PI (5% effort) $48,294 Mesenchymal stem cells for canine inflammatory brain disease 2016-2018 Center for Equine Health (CEH), University of California. PI (5% effort) $109,445 Mesenchymal stem cell therapy for neurological diseases of horses 2015-2017 Center for Equine Health (CEH- 16-16). PI (5% effort). $27,149 Equine recurrent uveitis: defining lymphocyte phenotype, lymphocyte function 2016-2017 and potential mechanisms of mesenchymal stem cell immunomodulation Center for Equine Health (CEH). Co-Investigator (PI:Spriet). 2% effort. $25,910 Stem Cell Tracking in the equine distal limb using Positron Emission Tomography. 2016-2018 Winn Feline Foundation. Co-Principal-Investigator (MT15-016, 2% effort, with B. Arzi) $41,494 A Multicenter Clinical Trial using Autologous Adipose-Derived Mesenchymal 2016-2017 Stem Cell Therapy for Cats with Chronic, Non-Responsive Gingivostomatitis Center for Equine Health (CEH), University of California. Co-PI (Co-PI: Athanasiou) $30,000 Self-assembly of chondrodifferentiated equine mesenchymal stem cells. 2015-2017 Center for Equine Health (CEH, Haas Family Foundation). PI (5% effort). $188,388 Identification of blood biomarkers for the detection and monitoring of degenerative 2015-2017 disorders of the equine foot

10

Center for Equine Health/ Stem Vita. PI (5% effort). $53,785 Safety of intraarticular and ocular administration of stem cell derived mediators in horses 2016-2017 NIH (NIAID), R21. 1R21AI116415-01 Co-PI with S. Dandekar. $275,000 Mesenchymal Stem Cell Therapy for Gut Mucosal Recovery in the SIV Model 2015-2017 of AIDS. 2% effort. AKC Canine Health Foundation. Co-investigator (PI: Fierro). $12,953 Pilot clinical trial to test the efficacy of Mesenchymal Stem Cells over-expressing 2015-2016 IL-10 to treat Osteoarthritis in elbows of senior dogs Center for Companion Animal Health (CCAH). Co-PI with A. Kol. $15,000. Th17 pathways as a target for mesenchymal stem cell therapy in dogs. 2015-2016 Center for Companion Animal Health (CCAH). Co-PI with B. Arzi $15,000 The immune profile of cats with chronic gingivostomatitis before and after 2015-2016 full-mouth extraction. Center for Companion Animal Health (CCAH). Co-PI with D. Simpson. $15,000 Development of cell-free regenerative medicine therapeutic for the treatment 2015-2016 of dilated cardiomyopathy. NIH (NIDCR), R21. 5R21DE024711-02 PI (15% effort). $275,000 Development of the Feline Chronic Gingivostomatitis Model for Stem Cell-Based 2014-2016 Regenerative Medicine. NIH (NHBLI), RO1. Co-investigator (5% effort) (Griffiths, PI). $1,250,000 Xenogeneic Scaffolds for Heart Valve Tissue Engineering. 2013- 2018 NIH (NIAID), K01. Mentor (5% effort). PI: Jen Johns. $275,000 Dynamics of neutrophil trafficking in Granulocytic Anaplasmosis 2011-2016 Center for Equine Health, University of California. Randall Grants. 2007-2015 Basic Science and Clinical Applications of Stem Cells in Regenerative Veterinary Medicine: Bone Regeneration. Borjesson, D (Project Leader). 10% effort. Funded 2012 grants (Borjesson PI): 1) The influence of mesenchymal stem cell (MSC) $50,000 culture expansion method on equine and canine MSC properties-- can MSC expansion be scaled up to meet good manufacturing practices? 2) Microbial interactions with $ 98,104 mesenchymal stem cells alters their anti-inflammatory phenotype and 3) Mechanisms underlying the downregulation of lymphocytes by equine $96,054 mesenchymal stem cells. Funded 2013 grants (Borjesson PI): Equine mesenchymal $113,669 stem cells for cutaneous wound repair Funded 2014 grants (Borjesson PI): Using Stem Cell Therapy to Treat Canine Inflammatory Bowel Disease $ 74,847 Winn Feline Foundation. Co-PI with B. Arzi (5% effort). $24,095 Allogeneic Adipose-Derived Mesenchymal Stem Cell Therapy for Syncytial Foamy 2014-2016 Virus-positive Cats with Chronic, Non-Responsive Gingivostomatitis. Center for Companion Animal Health (CCAH). PI (5% effort). $15,000 Immunomodulation by MSCs in canine inflammatory bowel disease. 2013-2014

11

Center for Equine Health (CEH), University of California. PI (5% effort). $29,600 Stem Cells Therapy to Facilitate Wound Healing in Horses. 2013-2014 Center for Equine Health (CEH), University of California. Co-Investigator (PI: Gericota) $72,678 Transplantation of dog neural crest stem cells in clinical dogs with spinal cord injury 2012-2013 as a model for translational human clinical trials. Winn Feline Foundation. Co-Investigator (PI: Arzi). $20,000 Autologous Adipose-Derived Mesenchymal Stem-Cell Therapy for Cats 2012-2014 with Chronic, Non-responsive Gingivostomatitis. Center for Companion Animal Health (CCAH). Co-investigator (PI: Spriet) $29,910 Tracking mesenchymal stem cells to target the liver. 2012-2014 Center for Companion Animal Health (CCAH). PI (5% effort). $30,000 Exploring the niche - a proposed role for hematopoietic niche dysregulation 2012-2014 in the pathogenesis of pancytopenia in dogs with chronic Ehrlichia canis infection. Center for Equine Health (CEH), University of California. Co-Investigator (PI: Hunt). $86,950 Effect of autologous mesenchymal stem cell treatment on liver development and 2012-2013 resolution of pathological abnormalities in dogs with congenital portosystemic shunt. Center for Companion Animal Health (CCAH). Co-investigator (PI: Arzi). $15,000 Autologous Adipose-Derived Mesenchymal Stem-Cell Therapy for Cats with Chronic, 2012-2013 Non-responsive Gingivostomatitis. Center for Equine Health, UC Davis. Co-Investigator (PI: JL Watson). $27,200 Molecular profile of equine hematopoietic stem/progenitor cells from peripheral 2011-2012 blood, bone marrow and umbilical cord blood. Marcia MacDonald Rivas Grant (CEH). (M. Vidal, PI) Co-investigator (5% effort). $40,000 Global and specific temporal expression of inflammatory, growth factor and 2010-2011 extracellular matrix proteins in acute diode laser-induced tendon lesions in horses after treatment with bone marrow-derived mesenchymal stromal cells. NIH (National Institute of Aging), Small Business Innovative Research (SBIR) $500,000 (Friedman PI at Thermogenesis/Vantus: Borjesson PI at UC Davis) 2009-2011 Allogeneic placental stem cells for tissue repair and regeneration. NIH, R21. Collaborator (5% effort). (PI: R. Vulliet) $525,000 LPL-Deficient Cats-A Quantitative Model For Gene Delivery. 2009-2011 ASVCP Share the Future Research Award. $2,500 Investigation of Hypercoagulability and Thrombosis in Dogs with Multicentric 2009 Lymphoma. Alamo Pintado. (J.L. Watson, PI) Collaborator (5% effort). $8,120 Reconstitution of a functional equine immune system in the mouse. 2009 Thermogenesis Corporation. Borjesson (PI), 5% effort $20,500

12

The role of soluble growth factors and 3-dimensional synthetic extracellular matrix 2008 composites in placental stem cell differentiation. Thermogenesis Corporation. Borjesson (PI), 5% effort $11,000 Administration of placental tissue-derived equine mesenchymal stem cells for use in 2008 related individuals. Center for Equine Health, University of California. Co-PI (10% effort). $34,300 Evaluation of post-transfusion survival of biotin labeled autologous erythrocytes 2007 in adult Thoroughbred horses. CVM Small Companion Animal Grants, University of Minnesota. Co-Investigator < 5% effort $9,000 Evaluation of microsatellite instability as a diagnostic test for transitional cell 2005 carcinoma of the lower urinary tract in dogs. Grant-in-Aid of Research, Artistry and Scholarship, University of Minnesota. PI $27,168 Anaplasma phagocytophila Infection of Megakaryocytes. 1/2004-6/2005 NIH, 3 year mentored clinician scientist award (KO8). PI (75% effort). $345,000 Granulocytic Ehrlichiosis: Cell-Pathogen Interactions. 2003-2006 CVM Small Animal Companion Grants. University of Minnesota. Co-I (Torres, PI) $5,000 Development of Canine Eosinophil Granule Protein Antibodies. 2004 CVM Small Animal Companion Grants, University of MN. Borjesson PI (5% effort) $5,000 Evaluation of Antithrombin III and D-Dimer Concentrations in Populations of 2003 Healthy and Clinically Ill Cats. REFERRED PUBLICATIONS: 1. Foutouhi S.H., N. Mohamad-Fauzi, D.B. Storey, A.A. Foutouhi, N. Kong, A. Kol, D.L. Borjesson, P.

Desai, J. Shah, J.D. Murray, and B.C. Weimer. Salmonella Enhances Osteogenic Differentiation in Adipose-Derived Mesenchymal Stem Cells [in review, BioRxiv].

2. Vapniarsky N., B. Arzi, N. Fazel, M. Kiuru, W. Murphy, N.J. Walker, E. Bulkeley, D.L. Simpson, P. Davari, E. Mills Ko, D.L. Borjesson. Histological, immunological, and genetic comparison of human oral lichen planus and feline chronic gingivostomatitis [in review, Stem Cell Development].

3. Goodale EC, E.K. Varjonen, C.A. Outerbridge, P. Bizikova, D.L. Borjesson, D.F. Murrell, A. Bisconte, M. Francesco, R. Hill, M. Masjedizadeh, S. Gourlay, S.D. White. Efficacy of a Bruton’s Tyrosine Kinase Inhibitor in the treatment of Canine Pemphigus Foliaceus [in review, Veterinary Dermatology].

4. Arzi B., S. Peralta, N. Fiani, N. Vapniarsky, N. Taechangam, U. Delatorre, K.C. Clark, N.J. Walker, M.R. Loscar, MJ Lommer, A. Fulton, J. Battig, D.L. Borjesson. A Multicenter Experience Using Shipped Adipose-Derived Mesenchymal Stem Cell Therapy for Cats with Chronic, Non-Responsive Gingivostomatitis [in review, Stem Cells Transl Med].

5. Taguchi T, D.L. Borjesson, C. Osmond, D.J. Griffon. 2019. Influence of Donor’s Age on Immunomodulatory Properties of Canine Adipose Tissue-Derived Mesenchymal Stem Cells. Stem Cells Dev. Oct 5. doi: 10.1089/scd.2019.0118. PMID:31588862

6. Saldinger L.K., S.G. Nelson, R.R. Bellone, M. Lassaline, M. Mack, N.J. Walker, D.L. Borjesson. 2019. Horses with Equine Recurrent Uveitis have an Activated CD4+ T Cell Phenotype that can be

13

Modulated by Mesenchymal Stem Cells In Vitro. Veterinary Ophthalmology. 22 August. https://doi.org/10.1111/vop.12704. PMID: 31441218

7. Taechangam N., S. Iyer, N.J. Walker, B. Arzi, D.L. Borjesson. 2019. Mechanisms utilized by feline adipose-derived mesenchymal stem cells to inhibit T-lymphocyte proliferation. Stem Cell Res Ther. Jun 25;10(1):188. PMID: 31238978.

8. Torrent A., M. Spriet, P. Espinosa, K.C. Clark, B. Vaughan, MB Whitcomb, D.L. Borjesson, L.D. Galuppo. 2019. Ultrasound-guided injection of the cranial tibial artery for stem cell administration in horses. Equine Vet J. Jan 8. doi: 10.1111/evj.13065. PMID: 30623489

9. Kaufman A.C., S.J. Robinson, D.L. Borjesson, M. Barbieri, and C.L. Littnan. 2018. Establishing hematology and serum chemistry reference intervals for wild Hawaiian Monk Seals (Neomonachus schauinslandi). J Zoo Wildl Med. Dec;49(4):1036-1040. doi: 10.1638/2017-039.1.PMID: 30592935

10. Espinosa P., Clark K.C., Verkh L., Zhigalko N., Simpson D.L., Martins-Amorim R., D.L. Borjesson Intra-articular administration of factors secreted by mesenchymal stem cells: safety in healthy equine joints and efficacy in a lipopolysaccharide induced synovitis model [in review, Veterinary Surgery].

11. White, J.L., N.J. Walker, J.C. Hu, D.L. Borjesson, K.A. Athanasiou. 2018. A Comparison of Bone Marrow and Cord Blood Mesenchymal Stem Cells for Cartilage Self-Assembly. Tissue Eng Part A. 2018 Apr 2. doi: 10.1089/ten.TEA.2017.0424. [Epub ahead of print] PMID: 29478385

12. Quimby J.M., and D.L. Borjesson. 2018. Mesenchymal stem cell therapy in cats: Current knowledge and future potential. J Fel Med and Surg [invited review]. Mar;20(3):208-216. doi: 10.1177/1098612X18758590. PMID: 29478398

13. Woods S.J., M. Spriet, N. Safra, D. D. Cissell, D.L. Borjesson. 2018. Hounsfield units are a useful predictor of pleural effusion cytological type in dogs but not in cats.Vet Radiol Ultrasound. Apr 23. doi: 10.1111/vru.12618. [Epub ahead of print]. PMID: 29687517.

14. Barberini D.J., M. Aleman, F. Aristizabal, M. Spriet, N.J. Walker, L.D. Galuppo, K.D. Woolard, R.Martins Amorim, D.L. Borjesson. 2018. Safety and tracking of intrathecal allogeneic mesenchymal stem cell transplantation in healthy and diseased horses. Stem Cell Res Ther. 2018 Apr 10;9(1):96. doi: 10.1186/s13287-018-0849-6. PMID: 29631634

15. Textor J.A., Clark K.C., Walker N.J., Aristizobal F.A., Kol A., Lejeune S.M., Bledsoe A., Davidyan A., Gray S.N., Bohannon-Worsley L.K., Woolard K.D., Borjesson D.L. 2017. Allogeneic Stem Cells Alter Gene Expression and Improve Healing of Distal Limb Wounds in Horses Stem Cells Transl Med. 2017 Oct 24. doi: 10.1002/sctm.17-0071. [Epub ahead of print] PMID: 29063737

16. Long C., L. Lankford, P. Kumar, D.L. Borjesson, D. Farmer, A. Wang. 2017. Isolation and Characterization of Canine Placenta-derived Mesenchymal Stromal Cells for the Treatment of Neurological Disorders in Dogs Cytometry A. 2017 Jul 17. doi: 10.1002/cyto.a.23171. [Epub ahead of print]. PMID: 28715613

17. Arzi B., K.C. Clark, A. Sundaram, F.J.M. Verstraete, N.J. Walker, M.R. Badgley, N. Fazel, W.J Murphy, N. Vapniarsky, D.L. Borjesson. 2017. Therapeutic Efficacy of Fresh, Allogeneic Mesenchymal Stem Cells for Severe Refractory Gingivostomatitis in Cats. Stem Cells Transl Med. 2017 Jun 15. doi: 10.1002/sctm.17-0035. [Epub ahead of print].PMID: 28618186

18. Clark K.C., F.A. Fierro, E. Mills Ko, N.J. Walker, B. Arzi, C. Tepper, H. Dahlenburg, A. Cicchetto, A. Kol, L. Marsh, W.J. Murphy, N.Fazel, D.L. Borjesson. 2017. Human and feline adipose-derived mesenchymal stem cells have comparable phenotype, immunomodulatory functions and transcriptome. Stem Cell Res Ther. Mar 20;8(1):69. PMID: 28320483.

19. Oki A.T., B. Huang, A.R. Beyer, L.J. May, H.K. Truchan, N.J. Walker, N.L. Galloway, D.L. Borjesson, J.A. Carlyon. 2016. Anaplasma phagocytophilum APH0032 is exposed on the cytosolic face of the pathogen-occupied vacuole and co-opts host cell SUMOylation. Front Cell Infect Microbiol. Sep 22;6:108. PMID: 27713867

14

20. Owens S.D., A. Kol, N.J. Walker, D.L. Borjesson. 2016. Allogeneic mesenchymal stem cell treatment induces specific allo-antibodies in horses. Stem Cell International. Volume 2016, Article ID 5830103, 8 pages. http://dx.doi.org/10.1155/2016/5830103. Epub 2016 Aug 28. PMID: 27648075

21. Kol A., N.J. Walker, M. Nordstrom, D.L. Borjesson. 2016. Th17 Pathway As a Target for Multipotent Stromal Cell Therapy in Dogs: Implications for Translational Research. PLoS One. Feb 12;11(2):e0148568. PMID: 26872054

22. Arzi B., E. Mills-Ko, F. J.M. Verstraete, A. Kol, N.J. Walker, M.R. Badgley, N. Fazel, W.J Murphy, N. Vapniarsky, D.L. Borjesson. 2016. Therapeutic Efficacy of Fresh, Autologous Mesenchymal Stem Cells for Severe Refractory Gingivostomatitis in Cats. Stem Cells Transl Med. Jan;5(1):75-86. Epub 2015 Nov 18. PMID: 26582907.

23. Clark K.C., A. Kol, S. Shahbenderian, J.L. Granick, N.J. Walker, D.L. Borjesson. 2016. Canine and equine mesenchymal stem cells grown in serum free media have altered immunophenotype Stem Cell Rev. Apr;12(2):245-56. PMID: 26638159

24. Kol A., B. Arzi, K.A. Athanasiou, D.L. Farmer, J.A. Nolta, R.B. Rebhun, X. Chen, L.G. Griffiths, F.J.M. Verstaete, C.J. Murphy, and D.L. Borjesson. 2015. Companion animals: Translational scientists’ new best friends. Sci Transl Med. Oct 7;7(308). PMID: 26446953. **selected for cover image

25. McMahill B.G., M.Spriet, S. Siso, M.D. Manzer, G. Mitchell, J. McGee, T.C. Garcia, D.L. Borjesson, M. Sieber-Blum, J.A. Nolta, B.K. Sturges. 2015. Feasibility Study of Canine Epidermal Neural Crest Stem Cell Transplantation in the Spinal Cord of Dogs. Stem Cells Transl Med. Oct;4(10):1173-86.PMID: 26273065

26. Arzi, B., G. D. DuRaine, C.A. Lee, D.J. Huey, D.L. Borjesson, B. Murphy, J.C.Y Hu, N. Baumgarth, K.A. Athanasiou. 2015. Cartilage immunoprivilege depends on donor source and lesion location. Acta Biomater. Sep 1;23:72-81. Epub 2015 May 28. PMID: 26028293

27. Kol A., J.A. Wood, D.D. Carrade Holt, J.A. Gillette, L.K. Bohannon-Worsley, S.M. Puchalski, N.J. Walker, K.C.Clark, J.L. Watson, D.L. Borjesson. 2015. Multiple intravenous injections of allogeneic equine mesenchymal stem cells do not induce a systemic inflammatory response but do alter lymphocyte subsets in healthy horses Stem Cell Res Ther. (1):73. Apr 15;6:73.PMID: 25888916

28. Morgan J.T., H. Sun Kwon, J.A. Wood, D.L. Borjesson, S.I. Tomarev, C.J. Murphy, P. Russell. 2015. Thermally labile components of aqueous humor potently induce osteogenic potential in adipose-derived mesenchymal stem cells. Exp Eye Res. 135:127-33. PMID: 25720657

29. Adedeji A.O., D.L. Borjesson, T.A. Kozikowski, A.N Cartoceti, J. Prutton, M. Aleman. 2015. What is your diagnosis? Cerebrospinal fluid from a horse. What is your diagnosis? Cerebrospinal fluid from a horse. Vet Clin Pathol. Mar;44(1):171-2. PMID: 25639591

30. Burton A.G., K.C. Clark, D.L. Borjesson, D.D. Carrade, J.W. Burges and S.D. Owens. 2015. Equine bone marrow volume reduction, red cell depletion and mononuclear cell recovery using the PrepaCyte®-CB processing system. Vet Clin Pathol. Jun;44(2):188-93.PMID: 25627833

31. Spriet M., G.B. Hunt, N.J. Walker, D.L. Borjesson. 2015. Scintigraphic tracking of mesenchymal stem cells after portal, systemic intravenous and splenic administration in healthy beagle dogs. Vet Radiol Ultrasound. May;56 (3):327-34. PMID: 25582730

32. Arzi B., A. Kol, B. Murphy, N.J. Walker, J.A. Wood, K. Clark, F.J.M. Verstraete, D.L. Borjesson. 2015. An endogenous retrovirus adversely affects feline mesenchymal stem cell culture and expansion: implications for animal model development. Stem Cells Dev. Apr 1;24(7):814-23. PMID: 25404388

33. Gericota B., D.L. Borjesson, M. Sieber-Blum, J.A. Nolta, B.K. Sturges. 2015. Stem Cells in Canine Spinal Cord Injury – Promise for Regenerative Therapy in a Large Animal Model of Human Disease Stem Cell Rev. Feb;11(1):180-93. PMID: 25173879.

15

34. Beyer, A.R., H.K. Truchan, L.J. May, N. J. Walker, D. L. Borjesson, and J.A. Carlyon. 2015. The Anaplasma phagocytophilum effector AmpA hijacks host cell SUMOylation. Cell Microbiol. Apr;17(4):504-19. PMID: 25308709 ** Selected for Editor’s Choice. ** Selected for cover image.

35. Screven R., E. Kenyon, M.J. Myers, H. F. Yancy, M. Skasko, L. Boxer, E.C. Bigley III, D.L. Borjesson, M. Zhu. 2014. Immunophenotype and gene expression profile of mesenchymal stem cells derived from canine adipose tissue and bone marrow. Vet Immuno Immunopath. Sep 15;161(1-2):21-31. PMID: 25026887

36. Kol A., S. Foutouhi, N.J. Walker, Kong, B.C.Weimer and D.L. Borjesson. 2014. Gastrointestinal microbes interact with canine adipose derived mesenchymal stem cells in vitro and enhance immunomodulatory functions in a distinct fashion. Stem Cells Dev. Aug 15;23(16):1831-43. PMID: 24803072.

37. Burton A.G., D. L. Borjesson, W. Vernau. 2014. Thymoma-associated lymphocytosis in a dog. Vet Clin Pathol. Dec;43(4):584-8. PMID: 25295998

38. Seidman D., N. Ojogun, N.J. Walker, J. Mastronunzio, A. Kahlon, K.S. Hebert, S.Karandashova, D. P. Miller, B.K. Tegels, R.T. Marconi, E. Fikrig, D.L. Borjesson, J.A. Carlyon. 2014. Anaplasma phagocytophilum surface protein AipA mediates invasion of mammalian host cells. Cell Microbiol. Aug;16(8):1133-45. PMID: 24612118

39. Carrade Holt D.D., J.A. Wood, J.L. Granick, K.C. Clark, and D.L. Borjesson. 2014. Equine mesenchymal stem cells inhibit T cell proliferation through different mechanisms depending on tissue source. Stem Cells Dev. Jun 1;23(11):1258-65. PMID: 24438346

40. Morgan J.T., J.A. Wood, N.J. Walker, V.K. Raghunathan, D.L. Borjesson, C. J. Murphy, P. Russell. 2014. Human Trabecular Meshwork Cells Exhibit Several Characteristics of, but are Distinct from, Adipose-derived Mesenchymal Stem Cells. J Ocul Pharmacol Ther. Mar-Apr;30(2-3):254-66. PMID: 24456002.

41. Gericota B., J. S. Anderson, G. Mitchell, D.L. Borjesson, B. K. Sturges, J.A. Nolta, M. Sieber-Blum. 2014. Canine Epidermal Neural Crest Stem Cells (cEPI-NCSC) – Characterization and Potential as a Therapy Candidate for a Large Animal Model of Spinal Cord Injury. Stem Cells Transl Med. Mar;3(3):334-45. PMID: 24443004

42. Park S.A., J.A Wood, C.M. Reilly, D.J. Chung, D.D. Carrade, S.L. Deremer, R.L .Seraphin, K.C. Clark, A.L. Zwingenburger, D.L. Borjesson, K. Hayashi, P. Russell, C.J. Murphy. 2013. Safety and immunomodulatory effects of allogeneic canine adipose-derived mesenchymal stem cells transplanted into the region of the lacrimal gland and gland of the third eyelid and the knee joint. Cytotherapy. Dec;15(12):1498-510.PMID: 23992828.

43. Toupadakis, C.A., J.L. Granick, M. Sagy, A. Wong, E. Ghassemi, D.J. Chung, D.L. Borjesson, C.E. Yellowley. 2013. Mobilization of Endogenous Stem Cell Populations Enhances Fracture Healing in Murine Femoral Fracture Model. Cytotherapy. Sep;15(9):1136-47. PMID: 23831362.

44. Granick, J.L., P.C. Falahee, D. Dahmubed, D.L. Borjesson, L.S. Miller, S.I. Simon. 2013. Staphylococcus aureus recognition by hematopoietic stem and progenitor cells via TLR2/MyD88/PGE2 stimulates granulopoiesis in wounds. Blood. 122(10):1770-8.

45. Carrade, D.D., and D.L. Borjesson. 2013. Immunomodulation by Mesenchymal Stem Cells in Veterinary Species. Comp Med. 63(3):207-17.

46. Kol A., Nelson R.W., Gosselin R.C., D.L. Borjesson. 2013. Characterization of thrombelastography over time in dogs with hyperadrenocorticism. Vet J. 197(3):675-681. PMID: 23838206

16

47. Kol A, S.L. Marks, K.A. Skorupski, P.H. Kass, T. Guerrero, R.C. Gosselin and D.L. Borjesson. 2013. Serial hemostatic monitoring of dogs with multicentric lymphoma. Vet Comp Oncol. May 25. [Epub ahead of print].

48. Sole A., M. Spriet, K. Padgett, B. Vaughan, L.D. Galuppo, D.L. Borjesson, E.R. Wisner, M.A. Vidal. 2013. Distribution and persistence of technetium-99 hexamethyl propylene amine oxime-labelled bone marrow-derived mesenchymal stem cells in experimentally induced tendon lesions after intratendinous injection and regional perfusion of the equine distal limb. Equine Vet J. Nov;45(6):726-31. PMID: 23574488.

49. Bohannon, L.K., S.D. Owens, N.J. Walker, .D.D. Carrade, L.D. Galuppo, D.L. Borjesson. 2013. The effects of therapeutic concentrations of gentamicin, amikacin, and hyaluronic acid on cultured bone marrow derived equine mesenchymal stem cells. Equine Vet J. Nov;45(6):732-6. PMID: 23448189.

50. Kahlon, A.., N. Ojogun, S.A. Ragland, M.J. Troese, D.Seidman, A.K. Ottens, J.E. Mastronunzio, H.K. Truchan, N.J. Walker, D.L. Borjesson, E.Fikrig, and J.A. Carlyon. 2012. Anaplasma phagocytophilum Asp14 (APH_0248) is an invasin that interacts with mammalian host cells via its C-terminus to facilitate infection. Infection Immunity. 81(1): 65-79.

51. Granick, J.L., S.I. Simon, and D.L. Borjesson. 2012. Hematopoietic Stem and Progenitor Cells as Effectors in Innate Immunity. Bone Marrow Res:165107. PMID: 22762001.

52. Ojogun N, A. Kahlon, S.A. Ragland, M.J. Troese, J.E. Mastronunzio, N.J. Walker, L. VieBrock, R.J. Thomas, D.L. Borjesson, E.Fikrig, and J.A. Carlyon. 2012. Anaplasma phagocytophilum outer membrane protein A interacts with sialylated glycoproteins to promote infection of mammalian host cells. Infection Immunity. 80(11): 3748-60.

53. Wood, J.A., I. Ly, D.L. Borjesson, P. Nealey, P. Russell, C.J. Murphy. 2012. The Modulation of Canine Mesenchymal Stem Cells by Nano-topographic Cues. Exp Cell Research. 318(19): 2438-45.

54. Kol, A., N.J. Walker, L.D. Galuppo, K.C. Clark, S. Buerchler, A. Bernanke, D.L. Borjesson. 2012. Autologous point-of-care cellular therapies variably induce equine mesenchymal stem cell migration, proliferation and cytokine expression. Equine Veterinary Journal. 45(2): 193-198.

55. Inoue, H., D. L. Clifford, T.W. Vickers, T.J. Coonan, D.K. Garcelon and D.L. Borjesson. 2012. Biochemical and hematologic reference intervals for the endangered island fox (urocyon littoralis). J. Wildl Dis. 48 (3): 583-592.

56. Carrade, D.D., M.W. Lame, M.S. Kent, K.C. Clark, N.J. Walker, D.L. Borjesson. 2012. Comparative analysis of the immunomodulatory properties of equine adult-derived mesenchymal stem cells. Cell Medicine. 4(1): 1-11.

57. Mudge, M., Walker, N.J., D.L. Borjesson, Johns, J.L, Librach, F., S.D. Owens. 2012. Post-transfusion survival of biotin labeled allogeneic RBCs in adult horses. Vet Clin Path. 41(1): 56-62.

58. Johns, J.L. and D.L. Borjesson. 2012. Proliferation and mobilization of hematopoietic stem and progenitor cells occur simultaneously with downregulation of CXCL12 signaling in acute Anaplasma phagocytophilum infection. Innate Immunity 18(3): 418 - 428.

59. Wood, J. Chung, D.J., Park, S.A., Zwingenberger, A.L., Reilly, C.M., Ly, I., Walker, N.J., Vernau W., Hayashi, K., Wisner, E.R., Cannon, M.S., Kass, P.H., Cherry, S.R., D.L. Borjesson, Russell, P., Murphy, C.J. 2012. Peri-ocular and intra-articular injection of canine adipose derived mesenchymal stem cells: an in vivo imaging and migration study. Journal of Ocular Pharmacology and Therapeutics 28(3): 307-317.

60. Sole A., Spriet M., Galuppo L.D., Padgett K.A., D.L. Borjesson, Wisner E.R., Brosnan R.J., Vidal M.A. 2012. Scintigraphic evaluation of intra-arterial and intra-venous regional limb perfusion of allogeneic bone marrow-derived mesenchymal stem cells in the normal equine distal limb using 99mTc-HMPAO. Equine Veterinary Journal. 44(5): 594-599.

17

61. Davies, R.S., J.E. Madigan, E. Hodzic, D.L Borjesson, J.S. Dumler. 2011. Dexamethasone-induced cytokine changes associated with diminished disease severity in horses infected with Anaplasma phagocytophilum. Clinical Vaccine Immunology. 18(11): 1962-1968.

62. Carrade, D.D., V.K. Affolter, C.A. Outerbridge, J.L. Watson., L.D. Galuppo, S.Buerchler V. Kumar, N. J. Walker, D.L. Borjesson. 2011. Intradermal Injections of Equine Allogenic Umbilical Cord Derived Mesenchymal Stem Cells do not Elicit Graft Rejection or a Delayed Type Hypersensitivity Reaction. Cytotherapy 13(10): 1190-1192.

63. Owens, S.D., J. Burges, J.L. Johns, D.D. Carrade, L.D. Galuppo, F. Librach, D.L. Borjesson. 2011. Processing of equine bone marrow using the automated MarrowXpress System: RBC depletion, volume reduction, and mononuclear cell recovery. Vet Clin Pathol: 40(4) 444-449.

64. Troese, M.J., A. Kahlon, S.A. Ragland, A.K. Ottens, N. Ojogun, K.T. Nelson, N.J. Walker, D.L. Borjesson, and J.A. Carlyon. 2011. Proteomic analysis of Anaplasma phagocytophilum during infection of human myeloid cells identifies a protein that is pronouncedly upregulated on the infectious dense-cored form. Infection Immunity. 79(11): 4696-4707.

65. Vidal, M.A., N.J.Walker, E. Napoli, D.L. Borjesson. 2012. Evaluation of senescence in mesenchymal stem cells isolated from equine bone marrow, adipose tissue and umbilical cord tissue. Stem Cells and Development. 21(2): 273-283.

66. Kim, M.H., J.L. Granick, C. Kwok, N.J.Walker, D.L. Borjesson, F.R. Curry, L.S. Miller, S.I. Simon. 2011. Neutrophil survival and c-kit+ progenitor proliferation in Staphylococcus aureus infected skin wounds promote resolution. Blood 117(12): 3343-3352.

67. Carrade, D.D., S.D. Owens, L.D. Galuppo, M.A.Vidal, G.L. Ferraro, F. Librach, S. Buerchler, M.S. Friedman, N.J. Walker, D.L. Borjesson. 2011. Clinicopathologic findings following intra-articular injection of autologous and allogeneic placentally-derived equine mesenchymal stem cells in horses. Cytotherapy 13(4) 419-430.

68. Mylonakis, M.E, D.L. Borjesson, L. Leontides, V.I. Siarkou, K. Theodorou, A.F. Koutinas. 2011. Cytologic patterns of lymphadenopathy in canine monocytic ehrlichiosis (Ehrlichia canis) Veterinary Clinical Pathology 40(1): 78-83.

69. MacNamara, K.C., Oduro, K.Martin, O.Jones, D. D.McLaughlin, M. Choi, D.L Borjesson, G.M. Winslow. 2011. Infection-Induced Myelopoiesis during Intracellular Bacterial Infection Is Critically Dependent upon IFN-γ Signaling. Journal of Immunology 186(2): 1032-1043.

70. Huang, B., M. J. Troese, Dale Howe, S. Ye, J.T. Sims, R. Heinzen, D.L. Borjesson, J.A. Carlyon. 2010. Anaplasma phagocytophilum APH_0032 is expressed late during infection and localizes to the pathogen-occupied vacuolar membrane. Microbial Pathogenesis 49 (5): 273-284.

71. Kol, A. and D.L. Borjesson . Thrombelastography / Thromboelastometry and its application to veterinary medicine – a literature review. 2010. Veterinary Clinical Pathology 39(4): 405-416.

72. Owens, S.D., J.L. Johns, N.J. Walker, F.Librach, D.D. Carrade, F. Tablin, D.L. Borjesson. 2010. In vitro biotinylation for determination of post-transfusion survival of fresh and stored autologous red blood cells in thoroughbred horses. AJVR 71(8): 960-966.

73. Toupadakis, C.A., Wong A., Genetos D.C., Cheung W.K., D.L. Borjesson, Ferraro GL, Leach JK, Galuppo LD, Owens SD, and Yellowley CE. 2010. Comparison of the osteogenic potential of equine mesenchymal stem cells from bone marrow, adipose tissue, umbilical cord blood and umbilical cord tissue. AJVR 71:1237-1245.

74. Huang, B., M.J. Troese, S.Ye, J. Sims, N.L. Galloway, D. L. Borjesson, J. A. Carlyon. 2010. Anaplasma phagocytophilum APH1387 is expressed throughout bacterial intracellular development and localizes to the pathogen-occupied vacuolar membrane. Infection and Immunity 78(5): 1864-1873.

18

75. Schaff, U.Y., K.A. Trott, J.L. Johns, J.A. Carlyon, S.I. Simon, D.L. Borjesson. 2010. Neutrophils exposed to Anaplasma phagocytophilum under shear stress fail to fully activate, polarize, and transmigrate across inflamed endothelium. American Journal Physiology-Cell Physiology 299(1): C87-96.

76. Carrade, D.D., J.E. Foley, D.L. Borjesson, J.E. Sykes. 2009. Canine Granulocytic Anaplasmosis: A Review. Journal Vet Internal Medicine 23(6): 1129-1141.

** ACVIM awarded this paper one of the top 5 downloaded articles from JVIM in 2009- 2010 77. Schuh, E.M., M. Friedman, D.D. Carrade, J. Li, D. Heeke, S. Oyserman, L. D. Galuppo, D.J.

Lara, N. J. Walker, G.L. Ferraro, S.D. Owens, D.L. Borjesson. 2009. Identification of variables that optimize isolation and culture of multipotent mesenchymal stem cells from equine umbilical-cord blood. American Journal Veterinary Research 70(12): 1526- 1535.

78. Bartholomew, S., S.D. Owens, G. L. Ferraro, D.L. Borjesson, D.D Carrade, D. J. Lara, L.D. Galuppo. 2009. Collection of Equine Cord Blood and Placental Tissues in Forty Thoroughbred Mares. Equine Veterinary Journal 41(8): 724-728.

79. Johns, J.L., K.C. MacNamara, N.J. Walker, G.M. Winslow, D.L. Borjesson. 2009. Infection with Anaplasma phagocytophilum Induces Multilineage Alterations in Hematopoietic Progenitor Cells and Peripheral Blood Cells. Infection and Immunity 77(9): 4070-4080.

80. MacNamara, K.C., R.Racine, M. Chatterjee, D.L. Borjesson, G.M. Winslow. 2009. Diminished Hematopoietic Activity Associated with Alterations in Innate and Adaptive Immunity in a Mouse Model of Human Monocytic Ehrlichiosis. Infection and Immunity 77(9): 4061-4069.

81. Yabsley, M.J., E. Greiner, F.S. Tseng, V. Joseph, M.M. Garner, M.H. Ziccardi, D.L. Borjesson and S. Zabolotzky. 2009. Description of Novel Babesia species and Associated Lesions from Common Murres (Uria aalge) from California. Journal of Parasitology 95(5): 1183-1188.

82. Borjesson, D.L., K.C. MacNamara, J.L. Johns and G.M. Winslow. 2009. Anaplasma phagocytophilum and Ehrlichia muris induce cytopenias and global defects in hematopoiesis. Clinical Microbiol Infect 15 (Suppl. 1) 1-2.

83. Schiller, K.A., M. Zillhardt, J. Alley, D.L. Borjesson, A. Beitz, and L.J. Mauro. 2009. Regulation of MCP-1 secretion in a novel tumor-bone co-culture model. BMC Cancer 9:45-53.

84. Johns, J.L., J.A. Luff, M.P. Shooshtari, A.M. Zehnder, D.L. Borjesson. 2009. What is your Diagnosis? Blood smear from an injured red-tailed hawk. Veterinary Clinical Pathology. 38(2): 247-252.

85. Granick, J.L., D.V. Reneer, J.A. Carylon and D.L. Borjesson. 2008. Anaplasma phagocytophilum infects cells of the megakaryocytic lineage through sialylated ligands but fails to alter platelet production. Journal of Medical Microbiology. 57: 416 – 423.

86. Kim, M.H., W. Liu, D.L. Borjesson, F.E. Curry, F. Liu, R.R. Isseroff and S.I. Simon. 2008. Dynamics of neutrophil infiltration and vascular permeability during cutaneous wound healing using fluorescence imaging. Journal of Investigative Dermatology. 128(7): 1812-1820.

87. Overmann, J.E., L. Sharkey, D. Weiss and D.L. Borjesson. 2007. Performance of Two Canine Microtiter Coombs' tests. Veterinary Clinical Pathology. 36(2): 179-183.

88. Brazzell, J.L., and D.L. Borjesson. 2007. Evaluation of plasma antithrombin activity and D-dimer concentration in populations of healthy, clinically ill, and cardiomyopathic cats. Veterinary Clinical Pathology. 36(1): 79-84.

89. Chou, J., A. Wunschmann, E. Hodzic and D.L. Borjesson. 2006. Detection of Borrelia burgdorferi DNA in Tissues from Dogs with Presumptive Lyme Borreliosis. J Am Vet Med Assoc. Oct 15; 229(8): 1260-1265.

19

90. Reif, J.S., M.M. Kliks, A.A. Aguirre, D.L. Borjesson, L. Kashinsky, and R. Braun. 2006. Gastrointestinal Helminths in the Hawaiian Monk Seal (Monachus schauinslandi): Association with body size, hematology and serum chemistry. Aquatic Mammals. 32(2): 157-167.

91. Brazzell, J.L., and D.L. Borjesson. 2006. What is your Diagnosis? Intraabdominal mass aspirate from a dog. Veterinary Clinical Pathology. 35(2): 259-262.

92. Brazzell, J.L., H. Kaese, and D.L. Borjesson. 2006. What is your Diagnosis? Transtracheal wash from a Jersey calf. Veterinary Clinical Pathology. 35(2): 247-249.

93. Borjesson, D.L., J.L. Brazzell, and R. Feferman. 2005. Platelet Dysfunction after Association with Anaplasma phagocytophilum in Vitro. Ann. N.Y. Acad. Sci. 1063: 1-3.

94. Berent, A.C., T. Murakami, R.S. Scroggin, and D.L. Borjesson. 2005. Reliability of Using Reagent Test Strips to Estimate Blood Urea Nitrogen Concentration in Dogs and Cats. J Am Vet Med Assoc. Oct 15;227(8):1253-6.

95. Borjesson, D.L., S.D. Kobayashi, A. R. Whitney, J.M. Voyich, C.M. Argue, and F.R. DeLeo. 2005. Insights into pathogen immune evasion mechanisms: Anaplasma phagocytophilum fails to induce an apoptosis differentiation program in human neutrophils. Journal of Immunology 174: 6364-6372.

96. Reif, J.S., A.M. Bachand, A.A. Aguirre, L. Kashinsky, D.L. Borjesson, R. Braun, and G.A. Antonelis. 2004. Morphometry, Hematology and Serum Chemistry in the Hawaiian Monk Seal (Monachus schauinslandi). Marine Mammal Science 20(4): 851–860.

97. Sims, C.S., A.H. Tobias, D.W. Hayden, D.M. Fine, D.L Borjesson, and B.A. Aird. 2003. Pericardial Effusion due to Primary Cardiac Lymphosarcoma in a Dog. Journal of Veterinary Internal Medicine 17(6): 923-927.

98. Borjesson, D.L., S.I. Simon, E. Hodzic, H.E.V. DeCock, C.M. Ballantyne and S.W. Barthold. 2003. Roles of Neutrophil B2 integrins in Kinetics of Bacteremia, Extravasation and Tick Acquisition of Anaplasma phagocytophila in Mice. Blood 101(8): 3257-3264.

99. Hodzic, E., S. Feng, K.J. Freet, D.L. Borjesson, and S.W. Barthold. 2002. Borrelia burgdorferi Population Kinetics and Selected Gene Expression at the Host-Vector Interface. Infection and Immunity 70(7): 3382-3388.

100. Borjesson, D.L. and S.W. Barthold. 2002. The Mouse as a Model for Investigation of Human Granulocytic Ehrlichiosis: Current Knowledge and Future Directions. Comparative Medicine 52(5): 403-413.

101. Borjesson, D.L., S.I. Simon, E. Hodzic, C.M. Ballantyne and S.W. Barthold. 2002. Kinetics of CD11b/CD18 upregulation during infection with the agent of Human Granulocytic Ehrlichiosis in Mice. Laboratory Investigations 82(3): 303-311.

102. Foley, J.E., D.L. Borjesson, T.L. Gross, C. Rand, M. Needham and A. Polland. 2002. Clinical, Microscopic and Molecular Aspects of Canine Leproid Granulomas in the United States. Veterinary Pathology 39(2): 234-239.

103. Borjesson, D.L., S.I. Simon, F. Tablin, S.W. Barthold. 2001. Thrombocytopenia in laboratory mice infected with the Agent of Human Granulocytic Ehrlichiosis. Journal of Infectious Diseases 184(11): 1475-1480.

104. Hodzic, E., D.L. Borjesson, S. Feng, and S.W. Barthold. 2001. Acquisition dynamics of Borrelia burgdorferi and the agent of human granulocytic ehrlichiosis at the host-vector interface. 2001. Journal of Vector-Borne and Zoonotic Diseases 1(2): 149-158.

105. Borjesson, D.L., M.M. Christopher and W. M. Boyce. 2000. Biochemical and hematologic reference intervals for free-ranging desert bighorn sheep. Journal of Wildlife Disease 36(2): 294-300.

20

106. Borjesson, D.L., M.M. Christopher and G. Ling. 1999. Detection of canine transitional cell carcinoma using a bladder tumor antigen urine dipstick test. Veterinary Clinical Pathology, 28(1): 33-38.

107. Borjesson, D.L., W.M. Boyce, I. Gardner, J. DeForge and B. Lasley. 1996. Pregnancy detection in bighorn sheep (Ovis canadensis) using a fecal-based enzyme immunoassay. Journal of Wildlife Disease, 32: 67-74.

108. Borjesson, D.L. and W. Szelistowski. 1989. Shell selection, utilization and predation in the hermit crab, Clibinarius panamensis in a tropical mangrove estuary. Journal of Experimental Marine Biology and Ecology, 133: 213-228.

BOOK CHAPTERS:

1. Borjesson D.L. 2019. Stem Cell Biology. In: Schalm’s Veterinary Hematology.

2. Borjesson, D.L and K.D. DeJong. 2014. Cytologic examination of the urinary tract. In: Atlas of

Canine and Feline Cytology. Raskin, RE and DJ Meyer, (eds). 3rd edition. W.B Saunders, Philadelphia, PA.

3. Borjesson, D.L. Pancreas Cytology. In: Diagnostic Cytology and Hematology of the Dog and Cat. 2014. Cowell, R.L., R.D. Tyler, J.H. Meinkoth, and DeNicola (eds). 2nd edition. Mosby, St. Louis, MO.

3. Peroni, J and D.L. Borjesson. Anti-Inflammatory and Immuno-Modulatory Activities of Stem

Cells. In: Veterinary Clinics of North America: Equine Practice (Regenerative Medicine). 27(2): 351-362. A. Stewart and M. Stewart (eds). Elsevier, Inc., Philadelphia, PA. 2011.

4. Borjesson, D.L. and J. Peroni. The Regenerative Medicine Laboratory: Facilitating Stem Cell

Therapy for Equine Disease. In: The Clinics of North America, Clinics in Laboratory Medicine. 31(1): 109-123. Christopher, MM (ed). Elsevier, Inc., Philadelphia, PA. 2011.

5. Borjesson, D.L and K.D. DeJong. Cytologic examination of the urinary tract. In: Atlas of Canine

and Feline Cytology. Raskin, RE and DJ Meyer, (eds). 2nd edition. W.B Saunders, Philadelphia, PA, 2009.

6. Borjesson, D.L. Pancreas Cytology. In: Diagnostic Cytology and Hematology of the Dog and Cat.

Cowell, R.L., R.D. Tyler, J.H. Meinkoth, and DeNicola (eds). Mosby, St. Louis, MO. 2008. 7. Borjesson, D.L. Culture, isolation and labeling of Anaplasma phagocytophilum for subsequent

infection of human neutrophils. In: Bacterial Pathogenesis: Methods and Protocols. Michael Otto and Frank R. DeLeo, (eds). The Humana press Inc. 2008.

8. Borjesson, D.L. Renal Cytology. In: Cytology. The Veterinary Clinics of North America: Small

Animal Practice 33: 119-134. Cowell, R.L. (ed). W.B. Saunders, Philadelphia, PA. 2003. 9. Borjesson, D.L. Cytologic examination of the urinary tract. In: Atlas of Canine and Feline

Cytology. Raskin, RE and DJ Meyer, (eds). W.B Saunders, Philadelphia, PA. 2001.

21

ABSTRACTS/ SCIENTIFIC PRESENTATIONS: 1. Borjesson, D.L. Immune Profiles of Cats with Feline Chronic Gingivostomatitis Prior to and After

Mesenchymal Stem Cell Therapy. [oral presentation]. North American Veterinary Regenerative Medicine Association (NAVRMA) Conference. September, 2019. Ontario, Canada.

2. Clark K.C., Borjesson D.L. Wang A. Translational Applications of Placenta-Derived Mesenchymal Stem Cells for the Treatment of Spina Bifida: A Canine Model. 2019. ISCT conference.

3. Taechangam, N., Arzi, B., Walker N.J., Borjesson, D.L. Mechanisms Utilized by Feline Mesenchymal Stem Cells to Inhibit T-Lymphocyte Proliferation [oral presentation]. 6th North American Veterinary Regenerative Medicine Association (NAVRMA) Conference, Sacramento, CA, September, 2018.

4. Saldinger, LK., Nelson S.G., Bellone R., Lassaline M., Borjesson, D.L. Adipose-derived mesenchymal stem cells as a potential therapy for equine recurrent uveitis. [oral presentation]. 6th North American Veterinary Regenerative Medicine Association (NAVRMA) Conference, Sacramento, CA, September, 2018.

5. Spriet M., Espinosa P., Walker N.J., Galuppo L.D., Borjesson D.L. Preliminary Experience with Positron Emission Tomography Stem Cell Tracking in the Horse [oral presentation]. 6th North American Veterinary Regenerative Medicine Association (NAVRMA) Conference, Sacramento, CA, September, 2018.

6. Amorim. R. M.; Clark, K. C.; Walker, N. J. ; Wang, A. ; Borjesson, D. L. Placental mesenchymal stem cells: A promising potential cell-based therapy for canine inflammatory brain disease. [poster]. World Stem Cell Summit, annual conference, West Palm Beach, FL, Dec. 2016.

7. K.C. Clark, F. Aristizabal, D. Schwartz, M. Spriet, N.J. Walker, D.L. Borjesson. Identification of blood biomarkers for the detection and monitoring of degenerative disorders of the equine foot. [poster]. World Stem Cell Summit, annual conference, West Palm Beach, FL, Dec. 2016.

8. S. J. Woods, M. Spriet, N. Safra, D.D. Cissell, D.L. Borjesson. Quantitative computed tomography analysis of pleural effusion in dogs and cats. [oral presentation]. American College of Veterinary Radiology annual conference, Florida, Oct. 2016.

9. Development of PRN1008, a novel, reversible covalent BTK inhibitor in clinical development for pemphigus. D Murrell1, S Gourlay2, R. Hill2, A. Bisconte2, P. Smith3, D. Karr2, C. Outerbridge4, K. Varjonen4, E. Goodale4, D. Borjesson4, V. Werth5, P. Nunn2, S. White4. Medical Dermatology Society. 2016.

10. Simpson D.L., L.D. Galuppo, D.L. Borjesson. A robust equine model of bone healing to evaluate regenerative therapies. [poster]. Stem Cell on the Mesa, Oct. 2015.

11. Mills Ko, E. and D.L. Borjesson. Adipose Derived Mesenchymal Stem Cell Therapy for Immune-

Mediated, Inflammatory Disorders in Veterinary and Human Medicine. [poster]. Stem Cell on the Mesa, Oct. 2015.

12. Outerbridge C., S. White K. Varjonen E.C. Goodale, D.L. Borjesson, D. Murrell, A. Bisconte, R.

Hill, M. Masjedizadeh, S. Gourlay. A new treatment for pemphigus foliaceus - Efficacy of the

22

Bruton’s Tyrosine Kinase inhibitor PRN473 in canine pemphigus foliaceus. 74th Annual Meeting of the American Academy of Dermatology, Washington DC, March 2016.

13. Textor JA, K.C. Clark, KD Woolard, F. Aristizabal, A. Kol, NJ Walker, A. Davidyan, S. LeJeune, L. Bohannon, D.L. Borjesson. Evaluation of Equine Mesenchymal Stem Cells for Cutaneous Wound Repair. [oral presentation]. 5th North American Veterinary Regenerative Medicine Association (NAVRMA) Conference, Asilomar, CA, July 2015.

14. Kol A., and D.L. Borjesson. Th17 pathway as a target for Mesenchymal Stem Cell Therapy in dogs. [oral presentation]. 5th North American Veterinary Regenerative Medicine Association (NAVRMA) Conference, Asilomar, CA, July 2015.

15. Arzi B., FM Verstrate, E. Mills Ko, NJ Walker and D.L. Borjesson. Fresh, cultured autologous

Mesenchymal Stem Cell therapy for non-responsive gingivostomatitis in cats. [oral presentation]. 5th North American Veterinary Regenerative Medicine Association (NAVRMA) Conference, Asilomar, CA, July 2015.

16. Arzi B, FM Verstrate, D.L. Borjesson. Mesenchymal stem cell therapy for feline chronic

gingivostomatitis: concept, progress and obstacles. European Congress of Veterinary Dentistry, 2015.

17. Russell P, J.T. Morgan, J.A. Wood, N. J. Walker, V.K. Raghunathan, D.L. Borjesson, C.J. Murphy

Trabecular Meshwork Exhibit Certain Characteristics of Adipose-derived Mesenchymal Stem Cells. Association for Research in Vision and Ophthalomology, May, 2014.

18. Clark, K.C., J. L. Granick, D.D. Carrade Holt, A. Kol, N.J. Walker, D.L. Borjesson. The influence

of culture conditions on equine MSC proliferation, surface phenotype and immune function. [Oral presentation]. 4th Annual NAVRMA conference, Atlanta, GA, Nov. 2013.

19. Spriet, M., G.B. Hunt, N.J. Walker, D.L. Borjesson. Scintigraphic comparison of 3 different techniques of administration of MSCs to the liver in dogs. [Oral presentation]. 4th Annual NAVRMA conference, Atlanta, GA, Nov. 2013.

20. Kol A., S. Foutouhi, N.J. Walker, B.C.Weimer and D.L. Borjesson. Gastrointestinal microbes

interact with canine adipose derived mesenchymal stem cells in vitro and enhance immunomodulatory functions in a distinct fashion. [Abstract-Presentation]. 5th International Stem Cell Meeting, Jerusalem, Israel. 2013,

21. Spriet M., G.B. Hunt, N.J. Walker, D.L. Borjesson. Scintigraphic comparison of 3 different

techniques of administration of mesenchymal stem cells to the liver of healthy research dogs. European Veterinary Diagnostic Imaging meeting. [Abstract-Presentation]. Portugal, Summer, 2013.

22. Duraine G.D., B. Arzi, D.J. Huey, D.L. Borjesson, B. Murphy, N. Baumgarth C.A. Lee, J. Hu, K.

Athanasiou. Success of articular cartilage implants is dependent upon anatomic location and graft-based immune reaction. ICRS meeting, 2013.

23. Clark, K.C., D.L. Borjesson, D.D. Carrade, J.W. Burges, S.D. Owens. Equine BM Volume

Reduction, RBC Depletion and MNC Recovery Using the PrepaCyte-CB Processing System. [Abstract-Presentation]. 3rd Annual NAVRMA conference, Savannah, GA, Nov. 2012.

23

24. Bohannon L.K., T.L. Sarrafian, T.C. Garcia-Nolan, N.J. Walker, D.D Carrade, P.H. Kass, K. Leach, B.Murphy, D.L. Borjesson, S.M. Stover, and L.D. Galuppo. Comparing Allogeneic and Autogenous BM-MSCs with Scaffolding in Equine Mandibular Bone Healing Model. [Abstract-Presentation]. 3rd Annual NAVRMA conference, Savannah, GA, Nov. 2012.

25. Carrade D.D., L.K. Bohannon, S.M. Puchalski, N.J. Walker, J.A.Gilette, L.D. Galuppo, J.L.

Granick, A. Kol, S.D. Owens, D.L. Borjesson. Multiple injections of allogeneic equine MSCs do not induce a systemic inflammatory response or alter lymphocyte reactivity in healthy horses. [Abstract-Presentation]. 3rd Annual NAVRMA conference, Savannah, GA, Nov. 2012.

26. Carrade D.D, J.L. Granick, K.C. Clark, and D.L. Borjesson. Mechanisms of equine mesenchymal

stem cell inhibition of T cell proliferation. [Abstract-Presentation]. 3rd Annual NAVRMA conference, Savannah, GA, Nov. 2012.

27. Sole A., M. Spriet, K.A. Padgett, M.E. Vaughan, L.D. Galuppo, D.L. Borjesson, E.R. Wisner,

M.A. Vidal. Scintigraphic in-vivo tracking of MSCs in an equine model of tendinopathy. [Abstract-Presentation]. 3rd Annual NAVRMA conference, Savannah, GA, Nov. 2012.

28. Burton AG, Vernau W, Borjesson DL. Thymoma and TCRγδ lymphocytosis in a dog. ASVCP

meeting, Seattle WA, December, 2012.

29. Moore S.B., S.R. Hollingsworth S.R., D.L. Borjesson, C.M. Reilly, R.J. Brosnan, T.H. Ferriera, L.D. Galuppo, D. Holve, J.A. Wood, P. Russell, N.J.Walker, D.D. Carrade, P.H. Kass, C.J. Murphy. Ocular Toxicity and Distribution of Allogeneic and Autologous Mesenchymal Stem Cells Following Intravitreal Injection into Normal Equine Eyes. [abstract-presentation], American College Veterinary Ophthalmology, 2012.

30. N.Ojogun, A. Kahlon, S. A. Ragland, M.J. Troese, J.E. Mastronunzio, N. J. Walker, L. VieBrock,

D.L. Borjesson, E.Fikrig, and J.A. Carlyon. Anaplasma phagocytophilum outer membrane protein A interacts with sialylated glycoproteins to promote infection of mammalian host cells. [abstract-oral presentation], American Society Rickettsiology, Park City, UT, July, 2012.

31. Murphy CJ, Park SA, Wood JA, Carrade DD, Reilly CM, Ly I, Chung DJ, Zwingenberger A,

Hayashi K, Cherry SR, Borjesson DL, and Russell P. Peri-ocular injection of MSCs: an in vivo safety, imaging and immunomodulation study. [abstract-oral presentation].Annual meeting of American College of Veterinary Ophthalmologists October, 2011.

32. Granick, JL, D.L. Borjesson, SI Simon. Hematopoietic stem and progenitor cells traffic to S.

aureus infected wounds where they proliferate and differentiate along the myeloid lineage in a MyD88 dependent manner. Society of Leukocyte Biology Annual Meeting, Kansas City, MO, Sept. 2011.

33. M. Spriet, A. Sole, L.D. Galuppo, K.A. Padgett, D.L. Borjesson, E.R. Wisner, R.J. Brosnan, M.A.

Vidal. Use of scintigraphy for in-vivo tracking of equine mesenchymal stem cells. European Veterinary Diagnostic Imaging Conference, London, September, 2011 [abstract-poster].

34. M. Spriet, A. Sole, L.D. Galuppo, K.A. Padgett, D.L. Borjesson, E.R. Wisner, R. J. Brosnan,

M.A. Vidal. In-vivo tracking of equine MSCs using Tc-HMPAO labeling and scintigraphy [abstract-oral presentation] North American Veterinary Regenerative Medicine Association, 2nd Annual meeting, June, 2011.

24

35. L.K. Bohannon, N.J. Walker, J.W. Burges, L.D. Galuppo, S.D. Owens, D.L. Borjesson. The Effects of Mixing Pharmaceuticals with Equine Stem Cells Prior to Treatment of Orthopedic Injuries in the Horse. [abstract-poster] North American Veterinary Regenerative Medicine Association, 2nd Annual meeting, June, 2011.

36. D.D. Carrade, V.K. Affolter, C.A. Outerbridge, J.L. Watson, L.D. Galuppo, S. Buerchler, V.

Kumar, N. J. Walker, D.L. Borjesson. Intradermal Injections of Equine Allogeneic Umbilical Cord Derived Mesenchymal Stem Cells are Well Tolerated and do not Elicit Immediate or Delayed Hypersensitivity Reactions. [abstract-poster] North American Veterinary Regenerative Medicine Association, 2nd Annual meeting, June, 2011.

37. A. Kol, N.J. Walker, L.D. Galuppo, K.C. Clark, S. Buerchler, A. Bernanke, D.L. Borjesson.

Soluble Factors Released from Adipose-Derived Progenitor Cells, Bone Marrow Mononuclear Cells, Cord Blood Mononuclear Cells and Platelet Lysate Induce Equine Mesenchymal Stem Cell Migration, Proliferation and Growth Factor Expression. [abstract-poster] North American Veterinary Regenerative Medicine Association, 2nd Annual meeting, June, 2011.

38. L.K. Bohannon, L.D. Galuppo, N.J. Walker, K.C. Clark, J.W. Burges, S.D. Owens, D.L.

Borjesson. Adverse reactions associated with clinical application of autologous and allogeneic bone marrow derived mesenchymal stem cells. [abstract-oral presentation] North American Veterinary Regenerative Medicine Association, 2nd Annual meeting, June, 2011.

39. Sole, A, M. Spriet, L.D. Galuppo, K.A. Padgett, D.L. Borjesson, E.R. Wisner, R.J. Brosnan, M.A.

Vidal.Evaluation of intra-arterial and intra-venous regional limb perfusion of mesenchymal stem cells in the normal equine distal limb using scintigraphy. [abstract-oral presentation] American College Veterinary Surgeons. 2011.

40. Wood, J.A., Chung, Dai-Jung, Park, Shin, A., Reilly, C.M., Carrade, D.D., Zwingenberger, A.,

Hayashi, K.,Cherry, S.R., Borjesson, D.L., Russell, P., and Murphy, C.J. Peri-Ocular and Intra-Articular Injection of Canine MSCs: An In Vivo Safety, Imaging, Migration, and Immunomodulation Study, International Society for Stem Cell Research, [abstract-oral presentation] June, 2011.

41. Bohannon, L.K., N.J. Walker, .J.W. Burges, L.D. Galuppo, S.D. Owens, D.L. Borjesson. The

Effects of Mixing Pharmaceuticals with Equine Stem Cells Prior to Treatment of Orthopedic Injuries in the Horse. [abstract-oral presentation] American College Veterinary Surgeons. 2011.

42. Murphy, C.J., S. A. Park, J. A. Wood, D. D. Carrade, C. M. Reilly, I. Ly, D. J. Chung, A.

Zwingenberger, K. Hayashi, S. Cherry, D.L Borjesson, and P. Russell. Peri-Ocular Injection of MSCs: An In Vivo Safety, Imaging, and Immunomodulation Study. Assoc for Research in Vision Science and Ophthalmology, [abstract-oral presentation] May, 2011

43. Granick, J.L., Min-Ho, D.L. Borjesson, S.I.Simon. Hematopoietic progenitor cells are involved in

the resolution of cutaneous Staphylococcus aureus abscesses. [abstract-poster].Host microbe Interactions, 5th Annual research retreat, Granlibakken, CA, Oct. 2010.

44. Watson, J.L., K.A. Jackson and D.L. Borjesson. Equine hematopoietic progenitor stem cells are

enriched in lineage-negative populations of cord blood mononuclear cells. [abstract-poster]. Conference of Research Workers in Animal Diseases (CRWAD), Chicago, IL 2010.

25

45. Johns, J.L., and D.L. Borjesson. Diminished SDF-1/CXCR4 signaling occurs simultaneously with hematopoietic stem and progenitor cell mobilization during acute A. phagocytophilum infection. [abstract-poster]. ISEH, Australia, 2010.

46. A. Kol, S.L. Marks, K.A. Skorupski, D.L. Borjesson. Serial Thromboelastographic Monitoring of

Dogs with Multicentric Lymphoma. [abstract-oral presentation]. ACVIM, Anaheim, CA. 2010. 47. CA.Wisner ER, Spriet M, Puchalski SM, Vidal MA, Galuppo LD, Walker NJ, Larson RF,

Borjesson D.L. Can magnetic forces be used to induce anisotropic migration of iron oxide labeled stem cells in normal tendon? [abstract-poster]. Contrast Media Research, 2009.

48. Yabsley, M.J., E. Greiner, F.S. Tseng, M.M.Garner, R.W. Nordhausen, M.H. Ziccardi, D.L.

Borjesson, S. Zabolotzky. Description of Novel Babesia specis and Associated Lesions from Common Murres (Uria aalge) from California. [abstract-poster]. Wildlife Disease Association, 2009.

49. E.M. Schuh, S.D. Owens, L. Galuppo, and D.L. Borjesson. Isolation and Characterization of

Mesenchymal Stem Cells from Equine Cord Blood. [abstract-poster]. ACVP annual meeting, San Antonio, November, 2008.

50. D.D Carrade, D. L. Borjesson, D. Lara, E. Schuh, S. Owens. Evaluation of the VetExpress Cell

Separation System for Equine Cord Blood Volume Reduction. [abstract-poster]. ACVP annual meeting, San Antonio, November, 2008.

51. Borjesson, D.L., K. MacNamara, J.L. Johns and G. Winslow. Anaplasma phagocytophilum and

Ehrlichia muris Induce Cytopenias and Global Defects in Hematopoiesis [abstract-poster]. 5th International Conference on Rickettsiae and Rickettsial Diseases, Marseille, France, May, 2008.

52. R. Davies, J.E. Madigan, E. Hodzic, D.L. Borjesson, and J.S. Dumler. Dexamethasone-induced

Redcution in IFN-γ Decreases Disease Severity in Horses Infected with Anaplasma phagocytophilum. [abstract-poster]. 5th International Conference on Rickettsiae and Rickettsial Diseases, Marseille, France, May, 2008.

53. K.C. MacNamara, K. Oduro, K. Choi, D.L. Borjesson, and G. Winslow. Alterations in

Hematopoietic Stem Cells and Committed Progenitor Cells Contribute to Hematological Abnormalities During Ehrlichiosis. [abstract-poster]. 5th International Conference on Rickettsiae and Rickettsial Diseases, Marseille, France, May, 2008.

54. Borjesson, D.L. and R. Feferman. Anaplasma phagocytophilum Infects Cells of the

Megakaryocyte Lineage and Alters Murine Megakaryopoiesis [abstract-poster]. Annual meeting of the American Society of Microbiology, May, 2006, Orlando, FL.

55. Overmann, J. D. L. Borjesson, D. Weiss and L. Sharkey. Performance of Two Canine Coombs'

Tests at a Veterinary Teaching Hospital [abstract-oral presentation]: Veterinary Clinical Pathology 34. Supplement: 284, 2005.

56. Borjesson, D.L., J.L. Brazzell, and R. Feferman. Platelet dysfunction and activation after

association with Anaplasma phagocytophilum in vitro [abstract-poster]: 4th International Conference on Rickettsiae and Rickettsial Diseases, Logroño, Spain, June 2005

26

57. Brazzell, J. L and D.L. Borjesson. Evaluation of plasma antithrombin III and D-dimer concentrations in populations of healthy and clinically ill cats [abstract-oral presentation]: Veterinary Clinical Pathology 33 (3): 183, 2004

58. M.M. Blauvelt, D.L. Borjesson and J.L Brazzell. Nucleated Red Blood Cells in clinically ill

dogs and cats may indicate increased risk of mortality [abstract-oral presentation]: Veterinary Clinical Pathology 32 (3): 154, 2003.

59. Borjesson, D.L., M.M. Christopher, and G. Ling. Evaluation of a bladder tumor antigen test for

diagnosis of canine transitional cell carcinoma [abstract-oral presentation]: Veterinary Pathology 34: 472, 1997.

60. Borjesson, D.L. and B.L. Lasley. Fecal-based enzyme immunoassays and pregnancy detection

[abstract-poster]: Society for the Study of Reproduction, Ann Arbor, MI, 1994.

OTHER PUBLICATIONS: 1. Borjesson, D.L. Ehrlichiosis: new perspectives on pathogenesis and diagnosis [proceedings]. 18th

Annual Veterinary Medical Forum, American College of Veterinary Internal Medicine, Seattle, 2000, pp. 574-578.

2. Borjesson, D.L. Cytology of sarcomas [proceedings]. Veterinary Cancer Society Conference,

Focus: Feline vaccine-associated fibrosarcomas, Bodega Bay, CA, pp. 1,4. 1999.

3. Borjesson, D.L. Handbook of cetacean cytology [book review]. 1999. Veterinary Clinical Pathology, 28(3): 115.

INVITED PRESENTATIONS:

1. Borjesson, DL. “Mesenchymal Stem Cells: Program Building to Product Use, UC Davis

Veterinary Clinical Trials”. Oregon State University, Dept of Biomedical Sciences Seminar Series, Corvallis, OR, October, 2019.

2. Borjesson, DL. “Cell Therapies Using the Dog and Cat as Models for Human Disease” International Society for Cell & Gene Therapy (ISCT), Madison, WI. September, 2019.

3. Borjesson DL. “Cytology: Decision Making in Practice”. Solano Pet Emergency and Solano

County Veterinarians Association, Fairfield, CA. August, 2019.

4. Borjesson DL. “Harnessing naturally occurring disease models to drive translational regenerative medicine”. California Animal Health and Food Safety Lab, San Bernardino, CA. March, 2019.

5. Borjesson, DL. “Insights into MSC immunomodulation: Informing potency assays and disease indications for MSC therapy”. CVM Food and Drug Administration (FDA) Rockville, MD, March 2019.

6. Borjesson DL. “Mentored by Dr. Barthold: Lessons Learned on My Path to Discovery”. CCM 20th anniversary symposium, Davis, CA, October 9th, 2018.

27

7. Borjesson DL. “The journey from curing oral inflammation in cats to initiating a human clinical trial: how a naturally occurring disease model drives translational regenerative medicine”. Animal Models in the Development and Implementation of Regenerative and Cell-based Therapies Symposium, University of Pennsylvania, Institute for Regenerative Medicine, October 3, 2018.

8. Borjesson DL. “The journey from curing oral inflammation in cats to initiating a human clinical trial”, 6th Annual Midwest Conference on Cell Therapy and Regenerative Medicine, Kansas City, September, 2018.

9. Borjesson DL. “Harnessing naturally occurring disease models to drive translational regenerative medicine” Keynote speaker, 19th Annual UC Bioengineering Systemwide, UC Riverside, June, 2018.

10. Borjesson DL. “My Pathway from bighorn sheep and helicopter safety to stem cell research and leadership”. Kansas State University, College of Veterinary Medicine. Phi Zeta Keynote Speaker, March, 2018.

11. Borjesson DL. “Time Management”. Faculty Leadership Academy. UC Davis, Jan. 2018

12. Borjesson DL. “The UC Davis Veterinary Institute for Regenerative Cures (VIRC): supporting

stem cell-based clinical trials for veterinary and human applications”. Bio-techne, Minneapolis, MN, Nov, 2017.

13. Borjesson DL. “The Veterinary Institute for Regenerative Cures (VIRC): supporting MSC therapy clinical trials focused on immunomodulation”. Hong Kong Veterinary Symposium, Hong Kong, Oct. 2017- Keynote Speaker

14. Borjesson DL. “Stem Cell Imaging and Tracking to Facilitate Translational Research”. miniEXPLORER Symposium, UC Davis. June, 2017.

15. Borjesson DL. “SVM-SOM Collaborative Clinical Trials-Cell Therapy”. 1st Pilot CTSC Retreat, UC Davis, MIND institute. May, 2017.

16. Borjesson DL. “Best Practices for Using Regenerative Medicine Products: Current Clinical

Trials and FDA guidelines”. Northern California Association of Equine Practitioners. Vallejo, CA. May, 2017.

17. Borjesson DL. “Introduction to Stem Cells and Regenerative Medicine”. Clinical Innovations in Regenerative Medicine, UC Davis, SVM Continuing Education Symposium. April, 2017.

18. Borjesson DL. “The Future of Stem Cell Therapy”. Clinical Innovations in Regenerative Medicine, UC Davis, SVM Continuing Education Symposium. April, 2017.

19. Borjesson DL. “From the Bench to Bedside: Current Clinical Trials Using Stem Cells in Cats, Dogs and Horses”. Comparative and Translational Regenerative Medicine Network (grand opening- keynote speaker). University of Guelph. April, 2017.

20. Borjesson DL. Allogenic stem cell applications in horses. 4th annual Current Veterinary Practices Symposium, Ghent, Belgium. March, 2017.

21. Borjesson DL. “Time Management”. Faculty Leadership Academy. UC Davis, Jan. 2017

28

22. Borjesson DL. Stem cell applications in horses. World Stem Cell Summit, Palm Beach, FL.

December, 2016.

23. Borjesson DL. Regenerative Medicine and One Health. American Association Medical Colleges Alumni Reception. Seattle, WA. November 2016

24. Borjesson DL. Stem Cells and the Immune System. Kansas Veterinary Regenerative Symposium, Manhattan, Kansas. June, 2016.

25. Borjesson DL. An Overview of Graduate Research Programs at the UC Davis School of

Veterinary Medicine. Chengdu University, China. February, 2016.

26. Borjesson DL. “Time Management”. Faculty Leadership Academy. UC Davis, Jan. 2016

27. Borjesson DL. “Stem Cell Therapy: Current Research Informing Clinical Medicine Applications in Veterinary Species”, American Association Zoological Veterinarians Annual Meeting, Portland, OR, October, 2015.

28. Borjesson DL. “Informing Clinical Trials: Stem Cell Function and Tracking”. 5th Annual North American Veterinary Regenerative Medicine Conference, Asilomar, CA, June, 2015.

29. Borjesson DL “It Takes a Team to Help Animals”. UC Davis. Spring Showcase. May, 2015

30. Borjesson DL. “Gastrointestinal microbe interactions with adipose-derived mesenchymal stem cells”. American Society of Microbiology Annual Meeting, May, 2015. New Orleans, LA (Workshop session: Stem Cells and Microbial Reprogramming of Host Cells and Tissues).

31. Borjesson DL. Fulfilling the promise of stem cell therapy using naturally-occurring large animal models of disease. University of Minnesota, April, 2015.

32. Borjesson DL. “Stem Cell Treatments for Inflammatory and Traumatic Diseases”. UC Davis Tahoe Environmental Research Center, Incline Village, Tahoe, January, 2015.

33. Borjesson DL. “Mesenchymal Stem Cells: Research, Translation and Fulfilling the Promise of Stem Cell Therapy using Naturally-Occurring Large Animal Models of Disease”. Stanford University, October, 2014.

34. Borjesson DL. “Stem Cell Therapies: Fact or Fiction”. AVMA hot topics. AVMA Annual Convention. July, 2014, Denver, CO.

35. Borjesson, DL. “Mesenchymal Stem Cells and Immunomodulation in Veterinary Medicine”. ACVIM forum, June, 2014, Nashville, TN.

36. Borjesson, DL. “Mesenchymal Stem Cells: Translation and Clinical Applications in Large and Small Animal Medicine”. ACVIM forum, June, 2014, Nashville, TN.

37. Borjesson, DL. “Fulfilling the promise of stem cell therapy using naturally-occurring large

animal models of disease”. AALAS 8th district annual meeting, San Francisco, CA, April, 2014.

29

38. Borjesson, DL. “Stem Cell Applications in Pets and Horses". Safety Services All Staff meeting, Davis, CA. January, 2014.

39. Borjesson, DL. “Immunomodulatory and Anti-inflammatory Properties of Mesenchymal Stem

Cells: Advances and Applications in Veterinary Medicine”. 3rd Annual North American Veterinary Regenerative Medicine Conference, Savannah, GA November, 2012.

40. Borjesson, DL. “A win for the races and for medicine”. Sacramento Valley American

Association for Laboratory Animal Science, Davis, CA, June, 2012. 41. Borjesson, DL. “Activated equine mesenchymal stem cells derived from fat, bone marrow and

placental tissues secrete specific mediators to modulate lymphocyte proliferation”, 2nd North American Veterinary Regenerative Medicine Conference, Lexington, KT, June, 2011.

42. Borjesson, D.L. Tick-borne diseases, 3- 3 hr. presentations, Veterinary Pathology Services,

Antwerp, Belgium, May, 2011.

43. Borjesson, D.L. “Stem Cells and Regenerative Medicine: From Clinical Use to the Research Bench and Back Again - The Science Behind the Promise”. Joint Winter Continuing Education Symposium (Veterinary Specialty Hospital and UC Veterinary Medical Center-San Diego). February, 2011.

44. Borjesson, D.L., S.D. Owens, G.L. Ferraro. Therapeutic Applications of Stem Cells. December,

2010. 12 hrs of lecture. Center for Veterinary Medicine, Federal Drug Administration, Rockville, MD.

45. Borjesson, D.L. Mesenchymal Stem Cells in Veterinary Medicine-Translating Research into

Cellular Therapy Products. UCD Clinical and Translational Science Center, Sacramento, CA. December, 2010.

46. Borjesson, D.L. Immunomodulatory Activity of Allogeneic Bone Marrow, Adipose and

Placentally Derived Equine MSCs. 1st North American Veterinary Regenerative Medicine Conference, Santa Ynez Valley, CA, 2010.

47. Borjesson, D.L. From Blood to Bone Marrow: Hematopoietic Suppression during Anaplasma

phagocytophilum Infection. Wadsworth Center, NY State Dept of Health, 2007. 48. Borjesson, D.L. Connecting the Dots: From Exposure to Infection to Disease to Diagnosis: The

Challenge of Diagnosing Tick-Borne Diseases. Student Chapter of the American Veterinary Medical Association Annual Meeting, Minneapolis, MN. 2005

49. Borjesson, D.L. Cytology workshop, 22nd Annual Veterinary Medical Forum, ACVIM,

Minneapolis, MN. 2004. 50. Borjesson, D.L. "Human Granulocytic Anaplasmosis: Pathogen-Host Cell Interactions".

National Institutes Allergy and Infectious Diseases, Rocky Mountain Laboratory, Annual science seminar, Hamilton, MT. 2004.

51. Borjesson, D.L. "Canine Lyme Disease, A Diagnostic Dilemma". Mather Lecture Series,

University of Minnesota, College of Veterinary Medicine, St Paul, MN. 2004.

30

52. Borjesson, D.L. Ehrlichiosis: new perspective on pathogenesis and diagnosis, 18th Annual Veterinary Medical Forum, American College of Veterinary Internal Medicine, Seattle, 2000.

53. Borjesson, D.L. Cytology of sarcomas, Veterinary Cancer Society Conference, Focus: feline

vaccine-associated fibrosarcomas, Bodega Bay, CA, 1999. CONTINUING EDUCATION PRESENTATIONS 1. Cytology. Summer Enrichment Program, UC Davis. 2008. 2. Stem Cells and Equine Regenerative Medicine. Kentucky Farms Managers Meeting. 2008. 3. Current and Future Research in Stem Cell Biology, Alamo Pintado, 2009. 4. Cytology. Summer Enrichment Program, UC Davis. 2009. 5. Small Animal Resident Physiology Board Review sessions: “Evaluation of Bone Marrow

Hematopoietic Disorders: Neoplasia, Dysplasia, Fibrosis and Necrosis”. 2010, 2012. 6. Student SAVMA symposium, UC Davis. 2011. 2-hr wet lab on case-based clinical pathology. 7. Veterinary School Hot Topics: “Stem Cell Research and Applications”. 2012. 8. Dentistry and Oral Surgery Journal Club: “Mesenchymal Stem Cells: An Overview and Their Role

in Immunomodulation”. 2012 9. Cytology Grand Rounds: “Mesenchymal Stem Cells and their Interaction with T cells- the

Potential for Immunomodulation in Veterinary Medicine". 2013. 10. Banfield Discovery Day. “Stem Cell Therapy for Inflammatory Diseases” Nov, 2013. 11. UC Davis “New Horizons Translational Research Colloquium”. March, 2016. Chair and Presenter:

Regenerative Medicine. 12. UC Davis. “The Immunomodulatory role of MSCs in feline and human chronic oral

inflammation”. November, 2016, Veterinary Institute for Regenerative Cures Seminar Series.