DMD 2012 Program

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Design of Medical Devices

Conference

University Hotel MinneapolisMinneapolis, MN

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Welcome! We are excited to present the 11th Annual University of Minnesota Design of Medical Devices Conference. The conference was created in 2001 to enhance collaboration between academia and industry, promote policy, research and educational initiatives as they relate to medical device design and to support medical devices education at the University of Minnesota.

This forum, uniquely positioned in the middle of one of the most significant medical device communities in the world, has provided invaluable insight and leadership to promote the future of this evolving industry. Conference attendance has more than tripled since its inception, and we look forward to continued growth.

The success of this conference is due in large part to the continued support from our industry sponsors and University of Minnesota partners. On behalf of the DMD Planning Committee, we thank you. We hope you enjoy this year’s conference!

Sincerely,

Arthur Erdman, Ph.D. Conference Chair

Paul Iaizzo, Ph.D. Conference Co-Chair

John Bischof, Ph.D. Conference Co-Chair

Dan Keefe, Ph.D. Conference Co-Chair

The Design of Medical Devices Conference is presented by the University of Minnesota Medical Devices Center (part of the Institute for Engineering in Medicine), the College of Science and Engineering, the Department of Mechanical Engineering and the Academic Health Center.

In Cooperation with the University of Minnesota Office of Business Relations.

DMD Corporate Sponsors

PremiereBoston Scientific CorporationMedtronic, Inc.Saitama Prefecture, JapanExecutiveMinnetronix, Inc. Associate3MLifeScience AlleySupportingAlandra MedicalCharacterization Facility UMN College of Science & EngineeringDepartment of Biomedical Engineering, University of MinnesotaDesign ConceptsExperimental Surgical ServicesIPrimeMaterialiseMedical Devices Center, University of MinnesotaMedical Industry Leadership Institute, Carlson School of Management Minnesota Science & Technology AuthorityMinntech Corporation Office of Business Relations, University of MinnesotaOffice for Technology Commercialization, University of MinnesotaPaR Systems, Inc.Scanlan GroupSIMULIASoftware Engineering Institute, Carnegie Mellon UniversityStarkey Hearing TechnologiesStratasys, Inc. Summit Medical, Inc. Supercomputing Institute, University of MinnesotaTechnological Leadership Institute, University of MinnesotaUNITE, University of MinnesotaValtronicXimedica

William Durfee, Ph.D. Conference Co-Chair

Just Herder, Ph.D. Contributed Papers Chair

Saurav Paul, Ph.D. Conference Co-Chair

Join us on twitter for live tweets of session topics and presentations during DMD! #dmdconf

April 9, 2012 - Medical Device Innovation Workshop: “Becoming a Medical Technology Innovator”

Tuesday, April 10, 2012 - Technical Sessions

Ballroom A Ballroom B Ballroom C A.I. Johnson Great Room Ski-U-Mah Minnesota

Room University Hotel Minneapolis McNamara Alumni Center

7:00 am Registration and Continental Breakfast (Prefunction Area)8:15 - 10:00 am Conference Welcome and Plenary Session10:00-10:30 am Sponsor Exhibit Showcase (Prefunction Area)

10:30 am-12:00 pm Neuroengineering 1 Micro & Nano

Devices 1 Cardiovascular 1 Human Factors 1

Neuroendovascular Devices for Treating Stroke and Vascular

Malformation

Engineered Tissues

12:15-1:45 pm Keynote Luncheon (Memorial Hall)

2:00-3:30 pm Neuroengineering 2 Micro & Nano Devices 2 Human Factors 2 Cardiovascular 2 Entrepreneurship

3:30-4:00 pm Sponsor Exhibit Showcase (Prefunction Area)

4:00-5:30 pm Prosthetics and Orthotics

Micro & Nano Devices 3 Cardiovascular 3

Valuing Early and Global Medical

Technology within a University

Medical Device Design

5:30-7:30 pm Medical Devices Industry Job Fair (Hubert H. Humphrey Ballroom)

International Student Design Showcase(Heritage Gallery)

Wednesday, April 11, 2012 - Technical Sessions7:00-8:15 am Registration and Continental Breakfast (Prefunction area)7:15-8:45 am 3-in-5 Competition

9:00-10:30 am Neuroengineering 3 Rehabilitation Robotics

FDA Innovation Initiative Cardiovascular 4 Medical Device

Innovation

10:30-11:00 am Sponsor Exhibit Showcase (Prefunction Area)

11:00 am-12:30 pm Neuroengineering 4 Surgical Robotics Cardiovascular 5

What’s New in Minnesota to

Support the Medical Device Industry

12:45-1:45 pm Award Keynote Luncheon (Memorial Hall)

2:00-3:30 pm Laser TherapiesPower for Implanted

Medical DevicesCardiovascular 6 Live Surgery

Computer-Aided Design of Medical

Devices3:30-4:00 pm Sponsor Exhibit Showcase (Prefunction Area)3:30-5:00 pm Scientific Poster Session 1 (Hubert H. Humphrey Ballroom)

Thursday, April 12, 20127:00 am Registration and Continental Breakfast (Prefunction Area)

Symposium: “Virtual Prototyping of Medical Devices” Technical Sessions

8:00-9:30 am Symposium Keynote Presentations Contributed Papers 1 Design for Global Health

9:30-10:00 am Sponsor Exhibit Showcase (Prefunction Area)10:00-11:45 am Symposium Keynote Presentations Orthopedics Contributed Papers 212:00-1:45 pm Keynote Luncheon and Awards (Memorial Hall)2:00-2:30 pm Sponsor Exhibit Showcase (Prefunction Area)2:00-3:30 pm Scientific Poster Session 2 (Hubert H. Humphrey Ballroom)3:30-4:30 pm Post Conference Tours - MDC, ESS, CREST, VH Lab (see page 10 for more details)

DMD 2012 Program Overview

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Additional Symposium Keynote Thursday, April 12, Ballrooms B-D, University Hotel Minneapolis

Update on Efforts to Support Medical Device Innovation

U.S. Senator Al Franken

Additions to the ProgrAm

Entrepreneurship Tuesday, April 10, 2:00-3:30, Ski-U-Mah, McNamara Alumni Center

Speaker Addition: The Role of Corporate Strategic Investment in the Mix of Start-up Financing - Panel Discussion

Erich A. Wolff, Director, Corporate Development, Medtronic, Inc

Medical Device Design Tuesday, April 10, 4:00-5:30, Ski-U-Mah, McNamara Alumni Center

Speaker Addition: Enhancing the Design Process via Knowledge Management

Ken Merdan, R&D Director, Design Services, Boston Scientific Corporation

Additional Luncheon Keynote Tuesday, April 10, 12:15, Memorial Hall, McNamara Alumni Center

The Importance of the Medical Device Industry in Minnesota

U.S. Senator Amy Klobuchar

Additional Symposium Keynote Thursday, April 12, Ballrooms B-D, University Hotel Minneapolis

Update on Efforts to Support Medical Device Innovation

U.S. Senator Al Franken

Three-in-Five Competition Wednesday, April 11, 7:15-8:45, Ballroom C, University Hotel Minneapolis

Affiliation Correction: Design, Development, and Validation of KIDS-CRRT - A Safe and Accurate Pediatric Continuous Renal Replacement Device

Arvind Santhanakrishnan, Georgia Institute of Technology

Presenter Change: Design of an Atraumatic Compliant Surgical Grasper

Alan Goyzueta, Department of Mechanical & Materials Engineering, University of Nebraska–Lincoln

Paper Withdrawn: HepatoSeal - Multimodal Mono-Bipolar Device for Liver Resection Surgery

Balakrishna Haridas and Mary Beth Privitera, M.Design, School of Energy, Environment, Biological and Medical Engineering, University of Cincinnati; Steven M. Rudich, MD, PhD, Department of Surgery, University of Cincinnati Georgia Institute of Technology

Cardiovascular 3 Tuesday, April 10, 4:00-5:30, Ballroom C, University Hotel Minneapolis Alex Hill, PhD, Principal Scientist, Structural Heart Research & Technology, Medtronic, Inc

Contributed Papers 1 Thursday April 12, 8:00-9:30, A.I. Johnson Great Room, McNamara Alumni Center Name and Title Change: Variable Assessment for Design of Monopolar Hot Biopsy Forceps

Randolph Robert, Department of Mechanical Engineering, Ohio University

Live Surgery Wednesday, April 11, 2:00, A.I. Johnson Great Room, McNamara Alumni Center Surgeon: Elizabeth Raskin, MD, Adjunct Assistant Professor of Surgery, University of Minnesota

Moderator: Genevieve Melton-Meaux, MD, Department of Surgery, University of Minnesota

Additional Job Fair Participants

Food and Drug Administration (FDA) Ware Technology Services

Additional Supporting Sponsor

ISIS Services

Design for Global Health Thursday, April 12, 8:00-9:30, Ski-U-Mah, McNamara Alumni Center Speaker Order Change: Innovating to Save More Lives

Harshad Sanghvi, Jhpiego, Johns Hopkins University

From De-tuned to De-signed - Medical Devices for the Emerging Markets

Mike Hess, Medtronic, Inc

The Magic of Science and Empathy

Jon Polhamus, GE Healthcare Global Design

Cardiovascular 5 Wednesday, April 11, 11:00-12:30, Ballroom C, University Hotel Minneapolis Speaker Order Change: Ablative Cardiac Therapies in the Clinic (UM experience)

Lin Yee Chen, MD, Cardiac Arrhythmia Center, University of Minnesota Medical School

Cryoablation Devices Description and Review for the Treatment of Heart Arrhythmia

Jean-Pierre Lalonde, Principal R+D Engineer, Medtronic CryoCath LP

Ablative Therapy Device Testing at the Cellular and Tissue Level

John Bischof, PhD, Mechanical Engineering, University of Minnesota

Ablative Therapy Device Testing in the Visible Heart Model

Paul A. Iaizzo, PhD, Department of Surgery, University of Minnesota

Symposium Thursday, April 12, 8:00-9:30, Ballrooms B-D University Hotel Minneapolis Title Change: Challenges and Trends for Developing Efficient Algorithms for Simulating Complex Medical Devices on Supercomputers

Birali Runesha, Director of Research Computing, University of Chicago

Tuesday, April 10

8:15 a.m. Ballrooms A-D

Conference Welcome and Plenary Session

Moderators: Arthur Erdman, Conference Chair and William Durfee, Conference Co-Chair

Medical Technology: A Case for Optimism

Dale Wahlstrom, President & CEO, LifeScience Alley and The BioBusiness Alliance of Minnesota™

Keynote Address:

Protein Analogous Micelles: Versatile, Modular Nanomachines

Matthew Tirrell Institute for Molecular Engineering, Searle Chemistry Laboratory University of Chicago

10:30 a.m. - 12:00 p.m. Concurrent Technical Sessions

12:15 p.m.

Keynote LuncheonSponsored by Boston Scientific Corporation

Moderator: Paul Iaizzo, Conference Co-Chair

Challenges and Opportunities in Neuroengineering: Understanding and Interfacing with the Brain

Bin He, PhD, Distinguished McKnight University Professor, Director, Center for Neuroengineering, University of Minnesota

(Keynote lunches are a separate billable event, meal tickets are required.)

Memorial HallMcNamara Alumni Center

NEUROENGINEERING 2: NEUROMODULATION

Session Organizer: Ballroom ATay Netoff, University of Minnesota

Establishing an Expectation for Device Science & Research: Demand the Evidence

Dwight Nelson Medtronic, Inc.

Current Steering with Deep Brain Stimulation Devices

Matt Johnson University of Minnesota

Caveat Emptor: When New EEG Technologies Don’t Mix

William Stacey University of Michigan

2:00 p.m. - 3:30 p.m. Concurrent Technical Sessions

NEUROENDOVASCULAR DEVICES FOR TREATING STROKE AND VASCULAR MALFORMATION

Ski-U-MahSession Organizer: McNamara Alumni CenterAfshin Divani, University of Minnesota

Bench-to-Bedside Translational Research in Stroke: The Era of Endovascular and Minimally Invasive Approach

Afshin Divani University of Minnesota

Large Animal Models for Stroke Device Development and Testing

Andrew Grande University of Minnesota

Flow Diversion for Treatment of Cerebrovascular Aneurysms: A Paradigm Shift

Bharathidasan Jagadeesan University of Minnesota

Endovascular Treatment of Brain AVMsGustavo Rodriguez University of Minnesota

Hemodynamics and Medical Device Treatment of Cranial Aneurysms

Ricky Chow Lake Region Medical

Novel Methods for Treating Stroke with New Endovascular Devices

Ramu Tummala University of Minnesota

HUMAN FACTORS 1: BREAKTHROUGHS IN PROSTHETIC AND EXOSKELETON DEVICES

A.I. Johnson Great RoomSession Organizer: McNamara Alumni CenterKathleen Harder, University of Minnesota

Impedance Control of a Powered Lower Limb Prosthesis

Brian Lawson Vanderbilt University

Innovation in Prosthetics – The Michelangelo Myoelectric Hand

Peter Nohre Otto Bock HealthCare

Robotic Mobility Assistance for Persons with Paraplegia: Experience, Issues, and Needs

Peter Neuhaus Florida Institute for Human and Machine Cognition (IHMC)

prefunction area

10:00 a.m. - 10:30 a.m.

SPONSOR EXHIBIT SHOWCASE

MICRO & NANO DEVICES 2Session Organizer: Ballroom B

Sang-Hyun Oh, University of Minnesota

Micro/Nano Devices for Biomedical ApplicationsYogish Kudva Mayo Clinic

Graphene Devices for In Vivo BiosensingSteven Koester Univesity of Minnesota

Cells, Nanowires, and Electrodes: Three Examples of Integrated Electrofludics Applied to Detection of Flow, Cells and Cell Health

Mark Tondra Diagnostic Biosensors, LLC

NEUROENGINEERING 1: NEUROIMAGINGSession Organizer: Ballroom ATaner Akkin, University of Minnesota

Real-time Brain Imaging and Neurofeedback: The Potentials for New Therapeutic Approaches

Sylvain Baillet MEG Research

MRI Mapping of the Human Basal Ganglia and Thalamic Connectome

Christophe Lenglet University of Minnesota

Advanced Diffusion Imaging of the Human Cervical Spinal Cord and Nerve Roots

Matthew Kang Regions Hospital

ENGINEERED TISSUES Minnesota RoomSession Organizer: McNamara Alumni CenterRobert Tranquillo, University of Minnesota

Next Generation Tissue Engineered Vascular GraftsChristopher Breuer Yale School of Medicine

In Vivo Remodeling of a Completely Biological Vascular Graft

Robert Tranquillo University of Minnesota

Tissue Engineering Lungs from Bone MarrowAngela Panoskaltsis-Mortari University of Minnesota

Biomimetic Extracellular Matrix using Purified Collagen, Elastin and Heparin: Vascular Scaffolding

David Masters Gel-Del Technologies, Inc.

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Monday, April 9

Medical Device Innovation Workshop: “Becoming a Medical Technology Innovator”

7:00 a.m.

Registration and Continental Breakfast

CARDIOVASCULAR 1: CARDIAC KEYNOTE PRESENTATIONS

Session Organizer: Ballroom CPaul Iaizzo, University of Minnesota

Development of Implantable Sensors to Assess Hemodynamic Impact of Cardiac Arrhythmias

David Benditt University of Minnesota

Research and Development of Cardiovascular Devices in the National Cerebral and Cardiovascular Center, Osaka, Japan

Yoshiyuki Taenaka National Cardiovascular Center (NCVC)

MICRO & NANO DEVICES 1Session Organizer: Ballroom BRajesh Rajamani, University of Minnesota

Medical MEMS Electrochemical Actuators and Sensors for Drug Delivery Applications

Ellis Meng University of Southern California

Flexible Electronics: Materials, Circuits, and Design Methodologies

Chris Kim University of Minnesota

Soft Tissue Tension Measurement in Orthopaedic Surgery

Kalpesh Singal, Joan Bechtold and Rajesh Rajamani University of Minnesota

o r d e r o f p r e s e n t a t i o n s m a y v a r y

CARDIOVASCULAR 2: PRE-CLINICAL TESTING OF NOVEL CARDIOVASCULAR DEVICES

A.I Johnson Great Room Session Organizer: McNamara Alumni CenterLarry Carrier, Claret Medical, Inc. Moderator: Michael Morton, Medtronic, Inc.

Considerations for Development of Novel ProductsDeclan Dineen Medtronic, Inc.

Interactive Panel Discussion on a “Widget”Michael Morton Medtronic, Inc.

Approach and Methodology for Pre-Clinical Assessments

John Zentgraf NeoChord, Inc.

Pre-Clinical Evaluation of Novel Cardiovascular Devices – A Case Study: Transcatheter Heart Valve Substitutes

Tim Kelley Medtronic, Inc.

How an FDA Reviewer Handles UnknownsChangfu Wu Food and Drug Administration

MICRO & NANO DEVICES 3Session Organizer: Ballroom BTianhong Cui, University of Minnesota

Micromachined Piezoelectrics for Medical Sensors and Transducers

Xiaoning Jiang North Carolina State University

Applications of BioencapsulationAlptekin Aksan University of Minnesota

MEMS-Based Polymer Hot Embossing for Medical Devices

Tianhong Cui University of Minnesota

CARDIOVASCULAR 3: CARDIOVASCULAR MODELING

Session Organizer: Ballroom C Alex Hill, Medtronic, Inc.

Comparison of the Motion at the Origin of the Left Subclavian Between Pigs and Humans

Srinivasan Varahoor Medtronic, Inc.

Computational Modeling of Cardiovascular DevicesCarl Popelar Southwest Research Institute

Regulatory Perspective on Computational ModelingTina Morrison Food and Drug Administration

VALUING EARLY AND GLOBAL MEDICAL TECHNOLOGY WITHIN A UNIVERSITY

A.I. Johnson Great HallSession Organizer: McNamara Alumni CenterSteve Parente, University of Minnesota

Market Scanning Technology OpportunitiesMichael Finch University of Minnesota

Assessing a New TechnologyRandall Nelson Evergreen Medical Technology, LLC.

Franchising University-based Medical Technology Valuation

Steve Parente University of Minnesota

INTERNATIONAL STUDENT DESIGN SHOWCASE

5:30 - 7:30 p.m. Heratige Gallery

McNamara Alumni Center

The purpose of this showcase is to promote and publicize excellence in medical device design by teams of undergraduate and graduate students conducted as part of their course work.

See page 13 for a list of presenters and judges

prefunction area

3:30 p.m. - 4:00 p.m.


HUMAN FACTORS 2: USABILITY OF REMOTE CONTROLLED MEDICAL DEVICES

Session Organizer: Ballroom C Richard Stein, Starkey Hearing Technologies

Panel Discussion:

The Product Development Process and Human Factors Engineering Inputs

Lars Runquist Redgroup

Form Follows Function: Participatory DesignSean Hagen BlackHagen Design

Designing a Robotic Surgery User Interface ConsolePaul Hattan Devicix, LLC

Mapping 3D Mouse Controls to a Remotely Driven Cardiac Catheter

Dean Hooper Ximedica


PROSTHETICS AND ORTHOTICSSession Organizer: Ballroom AAndrew Hansen, Northwestern University

The RIC Arm and Other DevelopmentsJon Sensinger Northwestern University

Sub-ischial Prosthetic Socket with Vacuum-Assisted Suspension for Persons with Transfermoral Amputation

Stefania Fatone Northwestern University

Design Issues and Development Process of a Wheelchair Mounted Mobile Arm Support

Just Herder Delft University

Terrain Detection & Terrain Adaption in Prosthetic Feet

Urs Schneider Fraunhofer Institute IPA

ENTREPRENEURSHIP Ski-U-Mah Session Organizer: McNamara Alumni CenterKaren Kaehler, University of Minnesota

Panel Discussion: The Role of Corporate Strategic Investment in the Mix of Start-up Financing

Max Fiore American Medical Systems, Inc.

J. Robert Paulson, Jr. NxThera, Inc.

Andrew M. Weiss CoAxia, Inc.

MEDICAL DEVICE DESIGN Ski-U-Mah Session Organizer: McNamara Alumni CenterMary Beth Privitera, University of Cincinnati

Understanding and Applying FDA Draft Guidance for Improved Usability in Medical Devices

Tor Alden HS Design

User TestingStephen Nelson Medtronic, Inc.

MEDICAL DEVICES INDUSTRY JOB FAIR

5:30 - 7:30 p.m.

Hubert H. Humphrey Ballroom

Participating Companies:Aerotek

Minnetech Corporation

St. Jude Medical

Starkey Laboratories, Inc.

Wednesday, April 11

7:15 a.m. Ballrooms B-D

THREE-IN-FIVE COMPETITION

Moderator: Saurav Paul, University of Minnesota

Mercury Boot: A Way to Speed Recovery and Reduce Vascular Complications from Lower Extremity Surgery or Trauma

Larry Nilsson Twin Cities Orthopedics

Cranial Drilling Tool with Retracting Drill Bit Upon Skull Penetration

Paul Loschak Harvard University

Device to Assist Force Generation in High-load Orthopedic Actions

Gabrielle Tuijthof Delft University of Technology

Design of an Atraumatic Compliant Surgical Grasper

Carl Nelson University of Nebraska–Lincoln

7:30 p.m.

ADJOURN


7:00 a.m.


6

Development of a Minimally Invasive Thrombectomy Device

Andrew Puffer The University of Toledo

Design, Development, and Validation of KIDS-CRRT - A Safe and Accurate Pediatric Continuous Renal Replacement Device

Arvind Santhanakrishnan University of North Carolina

Precision Pneumatic Robot for MRI-Guided Neurosurgery

David Comber Vanderbilt University

A Biocompatible Resorbable Microfastening SystemMaria M. Salamon Research Support Instruments

Magnetic Mechanism for Wireless Capsule BiopsyMassimiliano Simi Vanderbilt University

HepatoSeal - Multimodal Mono-Bipolar Device for Liver Resection Surgery

Balakrishna Haridas University of Cincinnati

Judges:Ryan Egeland, EntrepreneurReed Heimbecher, St. Jude Medical Mike Hess, Medtronic, Inc. Michael Hoey, EntrepreneurDanny Sachs, Entrepreneur Randy Schiestl, Boston Scientific Corporation

CARDIOVASCULAR 5: CARDIAC ABLATIVE THERAPIES

Session Organizers: Ballroom C John Bischof, University of Minnesota; Paul Iaizzo, University of Minnesota

Cryoablation Devices Description and Review for the Treatment of Heart Arrhythmia

Jean-Pierre Lalonde Medtronic CryoCath LP

Ablative Therapy Device Testing at the Cellular and Tissue Level

John Bischof University of Minnesota

Ablative Therapy Device Testing in the Visible Heart Model

Paul Iaizzo University of Minnesota

Ablative Cardiac Therapies in the Clinic (UM Experience)

Lin Yee Chen University of Minnesota

WHAT’S NEW IN MINNESOTA TO SUPPORT THE MEDICAL DEVICE INDUSTRY

A.I. Johnson Great Room Session Organizer: McNamara Alumni Center

Jeremy Lenz, The BioBusiness Alliance of

Minnesota™

Overview of the Next Generation Business Resource Network

Rebekah Kent The BioBusiness Alliance of Minnesota™

Company AccelerationTodd Leonard The Minnesota Angel Network

Technology Assessment and The Applied Business Center

Cheryl Matter The BioBusiness Alliance of Minnesota™

Regulatory Science InitiativeShaye Mandle LifeScience Alley

9:00 a.m. - 10:30 a.m. Concurrent Technical Sessions

NEUROENGINEERING 3: CLOSED-LOOP NEUROMODULATION

Session Organizer: Ballroom AMatt Johnson, University of Minnesota

Chaotic Desynchronization with Closed-loop Neuromodulation

Tay Netoff University of Minnesota

Closed-loop Deep Brain Stimulation to Suppress Beta Activity in Parkinson’s Disease

Chuck Dorval University of Utah

Translational Research Tools and Methods for Exploring Closed-loop Neuromodulation

Tim Denison Medtronic, Inc.

FDA INNOVATION INITIATIVESession Organizers: Ballroom CRalph Hall, University of Minnesota

Innovation IssuesPaul Sobotka Entrepreneur in Residence; Food and Drug Administration

The Payer/Provider View of InnovationRichard Justman United Health

Innovation InititativeRalph Hall University of Minnesota

REHABILITATION ROBOTICSSession Organizer: Ballroom BJust Herder, Delft University of Technology

Robotic Rehabilitation – Market Pull or Industry Push?

Stefan Bircher Hocoma, Inc.

Design and Development of an Ankle Rehabilitation Robot (ARBOT): From Research to Product Development

Jody Saglia Italian Institute of Technology

Rehabilitation Robots as Alternative Treatment of Tremor

Eduardo Rocon Bioengineering Group, CSIC

CARDIOVASCULAR 4: CARDIAC ELECTROPHYSIOLOGY AND MAPPING

A.I Johnson Great Room Session Organizer: McNamara Alumni CenterBin He, University of Minnesota

Electrophysiological Imaging of Cardiac Arrhythmias

Bin He University of Minnesota

Optical Mapping of Voltage and Calcium in the Heart

Alena Talkachova University of Minnesota

Cardiac Electrical Mapping Technologies for In Situ and In Vitro Research

Michael Bateman University of Minnesota

MEDICAL DEVICE INNOVATION Ski-U-MahSession Organizer: McNamara Alumni CenterSaurav Paul, University of Minnesota

Is It a Device?Anantanand Rambachan Saint Olaf College

Legal Issues in Medical Device InnovationRuth Okediji University of Minnesota

Medical Device Innovation and EntrepreneurismMichael Hoey NxThera, Inc.

NEUROENGINEERING 4: NEW ADVANCES IN ELECTRODE TECHNOLOGIES

Session Organizer: Ballroom A Hubert Lim, University of Minnesota

Towards a Reliable Neural Interface: Probe Scaling and Flexible Materials to Multi-modalities

Euisik Yoon University of Michigan

11:00 a.m. - 12:30 p.m. Concurrent Technical Sessions

SURGICAL ROBOTICSSession Organizer: Ballroom BTimothy Kowalewski, University of Washington

A Hopeful Vision of the Future of Surgical RoboticsRobert Sweet University of Minnesota

A Surgeon’s Perspective on Strengths and Weaknesses of Surgical Robots

Kenneth Liao University of Minnesota

Computational Surgery: A New Field of ResearchTimothy Kowalewski University of Washington

prefunction area

10:30 a.m. - 11:00 a.m.


o r d e r o f p r e s e n t a t i o n s m a y v a r y 7

Conducting Polymers for Next Generation Implantable Electrodes

Jeffrey Hendricks Biotectix, LLC.

Enhancing Neural Electrodes with NanotechnologyJohn Ferguson University of Minnesota

Rehabilitation Using FES to Induce Muscle Co-contraction

Paola Jaramillo Virginia Tech

CONTRIBUTED PAPERS 1: SAFE ACCESSA.I. Johnson Great Room

Session Organizer: McNamara Alumni Center

Just Herder, Delft University of Technology

Magnetic Mechanism for Wireless Capsule BiopsyMassimiliano Simi Vanderbilt University

Cranial Drilling Tool with Retracting Drill Bit Upon Skull Penetration

Paul Loschak Harvard University

Variable Assessment for Design Monopolar Hot Biopsy Forceps

Randy Robert Ohio University

Design and Development of a Novel Puncture Access Device

Nikolai Begg Massachusetts Institute of Technology

Measuring Force and Fluid Pressure During Epidural Needle Insertion

Dennis J. van Gerwen Delft University of Technology


DESIGN FOR GLOBAL HEALTHSki-U-Mah

Session Organizer: McNamara Alumni CenterKathleen Sienko, University of Michigan

Innovating to Save More LivesHarshad Sanghvi Johns Hopkins University

From De-tuned to De-signed - Medical Devices for the Emerging Markets

Mike Hess Medtronic, Inc.

8:00 a.m. - 9:30 a.m.


LASER THERAPIES: TREATMENTS FOR CANCER AND DISEASE

Session Organizers: Ballroom AJohn Bischof, University of Minnesota; Gal Shafirstein, Roswell Park Cancer Institute

Clinical Use of Laser Thermal Ablation in the Prostate, Liver and Brain

David Woodrum Mayo Clinic

KTP Laser Tissue Ablation: Development and Experimental Validation of a New Numerical Model

John Bischof University of Minnesota

Laser Therapy for Head and Neck TumorsGal Shafirstein Roswell Park Cancer Institute

Photodynamic Therapy for Head and Neck CancerMerrill Biel University of Minnesota

LIVE SURGERY A.I. Johnson Great Room

McNamara Alumni Center

A University of Minnesota surgeon will be performing a minimally invasive surgical procedure at the University of Minnesota Medical School-Fairview Hospital. The surgery will be transmitted to the conference via live video feed. A moderator will be at the conference explaining the procedure and passing questions from the audience along to the surgeon. The objective of the session is to discuss the strengths, weaknesses and design opportunities for the tools and devices used in modern surgery.

POWER FOR IMPLANTED MEDICAL DEVICES

Session Organizers: Ballroom BLeon Radziemski, University of Minnesota; Rajesh Rajamani, University of Minnesota

Transcutaneous Energy Transmission for Implanted Blood Pumps

William Weiss Penn State Hershey Medical Center

Primary Battery Technologies for Implantable Medical Devices

Michael Root Boston Scientific Corporation

Battery-Less Wireless Instrumented Knee Replacement Implant

Rajesh Rajamani University of Minnesota

Overview of Rechargeable Batteries for Implanted Medical Devices

Prabhakar Tamirisa Medtronic, Inc.

COMPUTER-AIDED DESIGN OF MEDICAL DEVICES

Ski-U-Mah Session Organizer: McNamara Alumni CenterVictor Barocas, University of Minnesota

Imaging Methods and Image Analysis for Validation of Computer Models of Brain Biomechanics

Philip Bayly Washington University

Thermal and Fluid Flow Simulations in Health Care: Product Development and Safety Improvement

John Abraham University of St. Thomas

Computational Modeling of Vagus Nerve Stimulation

Matt Johnson University of Minnesota

Ballrooms B-D

WELCOME AND INTRODUCTION

Art Erdman, University of Minnesota Conference Chair

KEYNOTE ADDRESSES:

Efficient Algorithms for Simulating Complex Medical Devices on Supercomputers

Birali Runesha, Director of Research Computing, University of Chicago

What Industry Needs for Medical Device Virtual Prototyping

Randy Schiestl, PMP, Vice President of Global Operations and Technology, Engineering Services Group, Boston Scientific Corporation

Thursday, April 12

5:00 p.m.

ADJOURN


3:30 p.m. - 5:00 p.m.

SCIENTIFIC POSTER SESSION I

A complete list of titles and authors can be found on pages 14-15.

prefunction area

3:30 p.m. - 4:00 p.m.


7:00 a.m. prefunction area


o r d e r o f p r e s e n t a t i o n s m a y v a r y o r d e r o f p r e s e n t a t i o n s m a y v a r y8

12:45 p.m.

KEYNOTE, AWARD AND LUNCHEON

Sponsored by Medtronic, Inc.

Moderator: Arthur Erdman, University of Minnesota

Welcome by Commissioner Mark Phillips, Minnesota’s Department of Employment and Economic Development (DEED)

Recipient of the 2012 Design of Medical Devices Conference Award

Origins of the Medical Device Industry and Its Future

Norm Dann, Adjunct Assistant Professor, Innovation Fellows Program, Medical Device Center, University of Minnesota


Memorial HallMcNamara Alumni Center

CARDIOVASCULAR 6: CARDIAC DEVICES IN THE PEDIATRIC POPULATION

Session Organizer: Ballroom C James St. Louis, University of Minnesota

Mechanical Cardiac Support in the Pediatric Population

Mark Plunkett University of Kentucky

Top Five Pediatric Specific Device NeedsGwyneth Fischer University of Minnesota Amplatz Children’s Hospital

Support for the Failing Myocardium in the Pediatric Population: The Next Generation

James St. Louis University of Minnesota

Percutaneous Pulmonary Valve Implantation - Available for Use, but Ready for Primetime?

Daniel Gruenstein University of Minnesota

Symposium:

Virtual Prototyping of Medical Devices

Ballrooms B-D

KEYNOTE ADDRESSES:

Can Virtual Prototyping Change How Medical Devices are Approved?

Brian Fitzgerald, Food and Drug Administration

Using Virtual Worlds to Prototype Medical DevicesRichard J. Boyd, Chief Architect, Lockheed Martin Virtual World Labs

DoD Virtual Human Technology Brief: How Intelligent Agents are Creating New Ways to Interact with Devices

Thomas B. Talbot, MD, USC Institute for Creative Technologies, Chief Scientist, TATRC Armed Forces Simulation Institute for Medicine

10:00 a.m. - 11:45 a.m.


Needs for Appropriate, Affordable, Safe Medical Devices

Adriana Velazquez Berumen World Health Organization

The Magic of Science and EmpathyJon Polhamus GE Healthcare Global Design

CONTRIBUTED PAPERS 2 : SMOOTH OPERATION

Ski-U-Mah Session Organizer: McNamara Alumni CenterJust Herder, Delft University of Technology

Adjustable Stiffness Guide Catheter for Intracranial Intervention

Dev Amatya North Carolina State University

Memorial Hall McNamara Alumni Center

LUNCHEON KEYNOTE AND AWARDS

Sponsored by Saitama Prefecture, Japan

Moderator: William Durfee, University of Minnesota

Awards:

Three-in-Five AwardsPresented by Saurav Paul, University of Minnesota

Presentation of the Inaugural Class: IEM Academy of Medical Device Innovators

Presentation of the IEM Directors AwardPresented by Jeffrey McCullough, University of Minnesota

Keynote:

Immersive Stereoscopic Reviews in a Virtual Vehicle Environment from the Customer’s Perspective

Elizabeth Baron, Director of the VR Lab, Ford Motor Company


12:00 p.m.

3:30 p.m.

ADJOURN


2:00 p.m. - 3:30 p.m.

SCIENTIFIC POSTER SESSION 2

A complete list of titles and authors can be found on page 16-17.

3:30 p.m.

Tour departures will take place near the Registration Desk. See the tour ad on the next page of the program for information about the facilities.

CREST www.CREST.umn.edu/

EXPERIMENTAL SURGICAL SERVICES www.ess.umn.edu/

MEDICAL DEVICES CENTER www.mdc.umn.edu/

THE VISIBLE HEART LABORATORY www.vhlab.umn.edu/

TOURS

prefunction area

9:30 a.m. - 10:00 a.m.



prefunction area

2:00 p.m. - 2:30 p.m.



ORTHOPEDICS: 3 R’S - RESEARCH, REGULATORY, AND REIMBURSEMENT

A.I. Johnson Great Room Session Organizer: McNamara Alumni CenterJoan Bechtold, Excelen Center for Bone and Joint Research and Education and Minneapolis Medical Research FoundationModerator: Jennifer Marrone, Regulatory & Clinical Research Institute, Inc., RCRI®

Regulatory: Planning for Project SuccessMary Beth Henderson Regulatory & Clinical Research Institute, Inc., RCRI®

Research in Relation to Regulatory and Reimbursement Issues

Matt Kyle Circle Biologics, Inc.

Reimbursement: Proving the Clinical and Economic Value of New Technology

Mary Fautsch Regulatory & Clinical Research Institute, Inc., RCRI®

Analysis of the Looping Problems in Colonoscopy Using Bending Sensors

JungHun Choi Ohio University

Development of a Minimally Invasive Thrombectomy Device

Andrew Puffer The University of Toledo

A Robot Calibration Method for Minimally Invasive Surgery

Xiaoli Zhang Wilkes University

Precision Pneumatic Robot for MRI-Guided Neurosurgery

David Comber Vanderbilt University

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INAUGURAL CLASS: IEM ACADEMY OF MEDICAL DEVICE INNOVATORS

Kurt Amplatz

Henry Buchwald

Perry L. Blackshear Jr.

Richard DeWall

Robert Kaster

C. Walton Lillehei

Otto Schmitt

Owen Wangensteen

Warren Warwick

Join us on twitter for live tweets of session topics and presentations during DMD! #dmdconf

Guided tour departures will take place near the Registration Desk.

Medical devices center www.mdc.umn.edu

Tuesday, April 10 at 10:00 a.m., Wednesday, April 11 at 10:30 a.m., Thursday, April 12 at 3:30 p.m.The Medical Devices Center at the University of Minnesota is a unique interdisciplinary program that resides within the Institute for Engineering in Medicine. The MDC aims to strengthen interdisciplinary research among faculty in the health sciences and engineering in areas specifically related to medical devices. The center trains the next generation of medical device inventors (including the Innovation Fellows Program) and fosters new relationships with the medical device industry and government agencies to improve health care worldwide.The tour will highlight the 4,000 square ft. facility that is configured to promote interdisciplinary medical device development including needs assessment, creative brainstorming, prototyping and testing.

center for research education and siMulation technologies (crest) www.crest.umn.edu

Thursday, April 12 at 3:30 p.m. CREST (Center for Research in Education and Simulation Technologies) is the associated research branch of SimPORTAL (Simulation PeriOperative Resource for Training and Learning), the simulation center for the University of Minnesota Medical School. The mission of CREST is to be a world leader in the research and development of novel curricula and simulation models to drive the future of healthcare professional education.At the heart of our simulation work is an innovative method for building accurate, 3D reconstructions of human anatomy. Using real patient MR and CT data as reference models, and cadaveric photography for accurate texturing, our lab can construct any organ system, catered specifically to any patient, condition, or surgical procedure. Our method allows us to build organ systems in a variety of resolutions, ranging from low end meshes ideal for volumetric simulation, to high end meshes used for photo realistic animation and illustration. We also have an artificial tissue lab with analogue models benchmarked against our human tissue database. CREST is also the host and for Live 3D visualization, recording, and streaming between the FV operating rooms, the Medical School and the Medical Devices Center.

the visible heart® laboratory www.vhlab.umn.edu/atlasThursday, April 12 at 3:30 p.m. Dr. Paul Iaizzo has been at the University of Minnesota since 1990, performing research and teaching graduate and undergraduate courses. In 1997, Dr. Iaizzo and his coworkers created the Visible Heart® laboratory in collaboration with Medtronic, Inc. Today, this lab is a premiere place to perform translational systems physiology research that ranges from cellular and tissue studies to organ and whole body investigations. The VH Lab also has a unique human heart library. The Visible Heart® lab embodies a creative atmosphere which is energized by some of the best and brightest students at the University. Our lab staff has over 100 years of collective research experience and functions as a highly efficient and productive team.

experiMental surgical services www.ess.umn.edu

Thursday, April 12 at 3:30 p.m. At Experimental Surgical Services, we are experts in designing and conducting the appropriate research to determine the safety and efficiency of medical devices. We have more than 25 years of experience in pre-clinical assessment for the medical industry. In fact, we are the industry leader in researching and testing cardiac devices and surgical techniques. We complete over 500 open heart procedures and over 1,500 procedures annually. ESS is Directed by Richard W. Bianco who has more than 25 years of experience in the pre-clinical assessment of virtually every animal model. The ESS staff of in-house surgeons work with device companies to develop and validate research methods, provide consultation as necessary and offer interpretative and technical support.

G U I D E D T O U R S F E A T U R E D E X H I B I T S

interactive visualization lab http://ivlab.cs.umn.edu/

Tuesday, April 10 at 2:15 - 3:00 p.m., Wednesday, April 11 at 2:15 - 3:00 p.m., No Tour on ThursdayIV Lab research involves data visualization,computer graphics, and human-computer interaction. Current projects include visualization of time-varying (motion) data, large-scale data visualization, perceptually optimized visualization, 3D user interfaces, haptics, and pen and multi-touch input techniques. Our work is supported by the National Science Foundation, National Academies Keck Futures Initiative, grants from industry, and the University of Minnesota. The research group includes about 10 undergraduate and graduate students. The IV lab in 2-203 Keller Hall is equipped with high-end graphics workstations that drive a series of innovative visual displays and interactive devices. Major equipment includes a Multi-Surface, Multi-Touch Virtual Reality Environment and a 3D Haptic (Force-Feedback) Display. We also work regularly with the visualization facilities at the Minnesota Supercomputing Institute.

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F E A T U R E D E X H I B I T S

Reminder to complete the DMD Attendee Survey by April 29th!

www.dmd.umn.eduAs a thank you for your participation, we will be randomly drawing two names from the pool of those who have successfully submitted the survey.

The prizes include:

(1) One Night Stay at the University Hotel Minneapolis in Minneapolis, MN (1) Full Registration Fees PAID for the DMD 2013 Conference

Winners will be notified shortly after the survey closes. Your input is greatly appreciated!

Hands on Hearts ExhibitApril 10-12, 8 a.m. - 4 p.m. Big Ten Room, University Hotel Minneapolis An interactive display of perfusion fixed human hearts courtesy of the Visible Heart Laboratory and the Department of Surgery. This is a unique library of human hearts received from organ donors and their families via LifeSource and the University of Minnesota’s Anatomy Bequest Program.

Perfusion fixation dilates these hearts as if they were filled with blood (diastole). Additionally, computer stations will introduce The Atlas of Human Cardiac Anatomy website and utilize during the display.

www.vhlab.umn.edu

ExploraDomeSponsored by The Bell Museum and the University of Minnesota Department of Computer Science and Engineering

April 10-12, 8:00 a.m. - 4:00 p.m. Maroon & Gold Room, McNamara Alumni Center The ExploraDome is a portable, immersive learning environment where attendees experience “hands-on, minds-on” medical device knowledge. The ExploraDome program features anatomy and/or medical devices delivered underneath a 25-foot diameter dome. This system is the first portable dome in the world built around the dynamic scaling software known as Uniview. The ExploraDome is sponsored by the Bell Museum and the University of Minnesota Department of Computer Science and Engineering.

Simulation Technologies SuiteApril 10-12, 8:00 a.m. - 4:00 p.m.Alumni Room, University Hotel Minneapolis Advanced surgical and medical simulators for training and learning. See the latest simulation equipment used for research and training from the University of Minnesota Center for Research in Education and Simulation Technologies (CREST). For more information visit the CREST website at http://www.crest.umn.edu/

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MEDICAL DEVICES CENTERThe Medical Devices Center at the University of Minnesota is a unique interdisciplinary program that resides within the Institute for Engineering in Medicine. The center has a combined mission of basic research, applied and translational research education and training as well as outreach and public engagement all related to medical devices.

The Medical Devices Center aims to strengthen interdisciplinary research among faculty in the health sciences and engineering specifically related to medical devices. The center trains the next generation of medical device inventors and fosters new relationships with the medical device industry and government agencies to improve health care worldwide.

The MDC has many roles within the University of Minnesota including:

* Accelerating interdisciplinary medical device R&D * Funding new medical device projects based on a rigorous peer review process * Maintaining a core lab with common use equipment for creative prototyping * Facilitating connections to other centers and labs * Supporting UMN functions related to medical devices * Supporting UMN teaching and training programs of departments related to medical devices * Interfacing with the medical device industry * Improving healthcare worldwide

Medical Devices Center

MDC INNOVATION FELLOWS PROGRAM

The University of Minnesota is recruiting a cross-disciplinary team interested in collaborative medical device innovation. Those encouraged to apply include: postgraduate engineers, experienced physicians as well as those in their residency or fellowship training, bio-scientists, seasoned medical device professionals, business professionals, IP attorneys, medical practitioners and others with a special interest in collaborating on medical device innovation and development. Applicants must be dedicated to improving human health and well-being.

Responsibilities: • Identifying clinical needs, inventing, and creating & testing prototype solutions. • Generating 15-20 patent disclosures related to medical devices for treatment or diagnostics. • Observing at the University of Minnesota Academic Health Center and other leaders in the medical device industry.Eligibility: • Degree in engineering, medicine, or biosciences. Medical or Doctorate degrees preferred. • Evidence of innovation. • One or more years of research training required.Benefits: • Monthly salary and health benefits are provided for one year starting August 27, 2012. • Use of first class facilities and access to top MD’s, PhD’s and professors of engineering & medicine

How to Apply: For more information please see the Medical Devices Center website www.mdc.umn.edu. You will need to submit a cover letter, resume or curriculum vitae, statement of medical device product innovation interests, and contact information for three references. Positions will be filled on a rolling basis as qualified applicants apply. (Requisition Number 176677). The application deadline is Friday, April 20, 2012.

Please contact the Center’s Director, Arthur Erdman with questions: [email protected] or 612.625.8580

The University of Minnesota Medical Innovation Fellows Program is sponsored by the University of Minnesota Medical Devices Center, part of the Institute for Engineering in Medicine.

The University of Minnesota is committed to the policy that all persons shall have equal access to its programs, facilities, and employment without regard to race, color, creed, religion, national origin, sex, age, marital status, disability, public assistance status, veteran status, or sexual orientation.

INNOVATORS WANTED! Applications Now Being Accepted for the Medical Devices Center Innovation Fellows Program 2012-2013 Team

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The purpose of this showcase is to promote and publicize excellence in medical device design by teams of undergraduate and graduate students that have been conducted as part of their course work. Outstanding student designs will be judged on their entry documents and the poster presented by the students at the showcase held durig the DMD Conference. Teams are competing for one of three cash prizes: $500, $300, and $200.

# Title Author and Affliliation

1 Bison Microventure Cody Mathison, Andrew Dalman, Brittany Korynta, and Dustin Mueller, Manufacturing Engineering, North Dakota State University

2 Design of a Fully-Implantable Miniature Cardiac Electrical Stimulator for Research Purposes in a Rat

Andy Crisman, Department of Biomedical Engineering, University of Minnesota

3 The Solution to Postpartum Hemorrhage Anastasia Borok, Adam Clark, Luke Jungles, and Nathaniel Moller, Center for Bioengineering Innovation and Design, Johns Hopkins University

4 Mobile Vision: The Mobile Optometry Clinic Kevin Beale, George Chen, Richard Latimer, Minhee Park, and Adam Samaniego, Departments of Electrical Engineering and Bioengineering, Rice University

5 Flexible Endoclips for Effective Hemostasis of Gastrointestinal Bleeds

Barath Udayasuryan, Divya Sanghvi, and Krishan Prem Kumar, Department of Biomedical Engineering, University of Michigan

6 The Globoscope: A Cost-Effective, Portable Option for Endoscopy in Low-Resource Settings

Rebecca Hernandez, Charisma Kaushik, Jean Kim, Amy Liao, and Sabha Momin, Bioengineering, Rice University

7 Pneumatically Actuated Automated Suturing Device for Rapid Closure of Long Surgical Incisions

Carmen M. Graves, Faye Y. Wu, Steven Lam, Omar Y. Carrasquillo, Andrew T. Erickson, and Kyle R. Eberlin, Mechanical Engineering Department, MIT

8 BabyBeats: Fast, Reliable and Low-Cost Fetal Heart Rate Monitor

Lauren Smith, Brian Rayburn, Creighton Petty, and Geoffrey Russell, Biomedical Engineering Department, Center for Bioengineering Innovation and Design, Johns Hopkins University

9 Needle Tip and Syringe Pistol Design to Maximize Cellular Uptake in Thyroid Fine Needle Aspiration Biopsies

Robert Brik, Kevin Chen, Jisoo Kim, and Alex Speltz, Department of Mechanical Engineering, MIT; Alex Lesman, Electrical Engineering and Computer Science, MIT; William C. Faquin and Sareh Parangi, Massachusetts General Hospital

10 The SinuGlide Device: An insert for treatment of chronic sinusitis

Anastasia Borok, Creighton Petty, Lauren Smith, and Matron Varady (MSE Candidates), Department of Biomedical Engineering, Johns Hopkins University

11 An Assisted Obstetric Delivery Device for Resource Limited Settings

John P. Hessburg, Prithvi Murthy, Keval D. Patel, Daniel P. Ostrowski, and Kathleen H. Sienko, Depts of Biomedical and Mechanical Engineering, University of Michigan

12 Minimally-Invasive Specimen Removal with Contractible Mesh

Erika M. Bildsten, Deema Totah, Tyrel Waagen, Subarna Basnet, and Melody Kuna, Department of Mechanical Engineering, MIT; Ian Makey, Beth Israel Deaconess Medical Center

13 Design of an Assisted Blood Flow Occlusion Device for Liver Resection

Matthew Estrada, Yashraj Narang, Randall Briggs, Yamicia Connor, and Daniel Fourie, Department of Mechanical Engineering, MIT

14 On-chip bacterial detection and diagnosis with integrated mechanical micropump for low-resource settings

Ayeeshik Kole, Erica Curtis, and Erik Werner, Department of Biomedical Engineering, Vanderbilt University; Brian Lesniak and Ben Brantley, Department of Mechanical Engineering, Vanderbilt University

15 Cell phone based decision making and referral platform for pregnancy related complications in rural settings

Amir Sabet Sarvestani, Alparslan Emrah Bayrak, Vaibhav Jaguste, Alex Gardner, and Kathleen Sienko, University of Michigan, Mechanical and Biomedical Engineering Department

16 MAID: Magnet-Assisted Intubation Device Alexander Cooper, Elizabeth Flanagan, Shawna Hagen, and Jacob Thompson, Department of Biomedical Engineering, Georgia Institute of Technology

Showcase JudgesAlec Johnson, University of St. ThomasChristopher Scorzelli, Kablooe Design

Jay Kokate, Boston Scientific Corporation Jorie Soskin, Medtronic, Inc.

Karen Kaehler, Office for Technology Commercialization, UMNScott Smith, Medical Design Consultant

International Student Design ShowcaseTuesday, April 10, 5:30pm-7:30pm, Heritage Gallery, McNamara Alumni Center

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Scientific Poster Session 1 Wednesday, April 11, 3:30 p.m. - 5:30 p.m.

Hubert H. Humphrey Ballroom, University Hotel Minneapolis

Final one-page papers were published in the March 2012 Issue of the ASME Journal of Medical Devices Final one-page papers were published in the March 2012 Issue of the ASME Journal of Medical Devices

1. Combined bone-implant fixation : A pre-clinical hip stem evaluation Antonio Completo, Jose Simões, Fernando Fonseca, Antonio Ramos, Carlos Relvas, Mario Oliveira, Joana Pereira, and Susana Meireles, Department of Mechanical Engineering University of Aveiro, Portugal

2. Delivery of Warm Sclerosant Via Dual Balloon Catheter for Treatment of Venous Hypertension and Leg Ulcers Will Drasler, Kevin Nickels, and Gary Sullivan

3. Left-sided Epicardial Pacing Via A Transvenous Lead Delivery Julianne H. Eggum, Ryan P. Goff, David G. Benditt, Paul A. Iaizzo Departments of Surgery, Biomedical Engineering, and Medicine, University of Minnesota

4. In Vitro Testing of Trileaflet Polymer Heart Valves for Children Brianna Roux, Rose-Hulman Institute of Technology; Linxia Gu, Ph.D., Department of Mechanical and Materials Engineering, University of Nebraska-Lincoln

5. Experimental Study of Stent Conduit Interactions Shijia Zhao, Linxia Gu, Ph.D., Department of Mechanical and Materials Engineering, University of Nebraska-Lincoln

6. Development of a Real-time Heart Monitoring System for a Smart Phone DuckHee Lee, Ahmed Rabbi, and Reza Fazel-Rezai, Department of Electrical Engineering, University of North Dakota

7. Development of a Minimally Invasive Thrombectomy Device Andrew Puffer and Mohammad Elahinia, Ph.D., Nitinol Commercialization Accelerator, Department of Mechanical Engineering, The University of Toledo; Christopher Cooper, MD, Department of Cardiovascular Medicine, The University of Toledo Medical Center

8. Hemodynamics of AV Grafts for Hemodialysis Access Matthew Nelson and John Abraham, School of Engineering, University of St. Thomas

9. Development of The Embolic Protection Filter Device Modified With The Novel Antithrombogenic Polymer Hirokazu Sakaguchi, Yuka Sakaguchi, Kazuhiro Tanahashi, Medical Devices & Materials Research Unit, Advanced Materials Research Labs., Basic Research Center, Toray Industries, Inc.; Kyokun Uehara, Department of Cardiovascular Surgery, Graduate School of Medicine, Kyoto University; Mitsuru Sato, Yoshimasa Nagata, Kanji Inoue, PTMC Laboratory

10. Safe And Rapid Monitoring Of Transcutaneous Gases Using A Novel Non-Equilibruim Approach Madhubanti Chatterjee, Xudong Ge, Yordan Kostov, Govind Rao, Center for Advanced Sensor Technology (CAST), Department of Chemical and Biochemical Engineering, University of Maryland

11. The Quantification of Anatomical Dimensions within Fixed Cardiac Specimens Using Echocardiography Amanda L. Martel, Departments of Biomedical Engineering; Michael G. Bateman, Departments of Biomedical Engineering and Surgery University of Minnesota; Hanna R. Iaizzo, Department of Surgery University of Minnesota; Erica M. Hjelle, Department of Surgery University of Minnesota; Paul A. Iaizzo Departments of Biomedical Engineering and Surgery University of Minnesota

12. Using the Atlas of Human Cardiac Anatomy to aid in the Design of Cardiac Devices Christopher D. Rolfes, Department of Surgery and Biomedical Engineering, Medtronic, Inc.; Jason L. Quill, Medtronic, Inc.; Michael G. Bateman, Department of Surgery and Biomedical Engineering, Medtronic, Inc.; Alexander J. Hill, Medtronic, Inc.; Michael D. Eggen, Medtronic, Inc.; Paul A. Iaizzo, Department of Surgery and Biomedical Engineering

13. MRI-Compatible Guide-Wire with Improved Maneuverability for Endovascular Interventions Helene Clogenson, John van den Dobbelsteen, Jenny Dankelman, Delft University of Technology

14. Heart Sound Detection Using Laser Technology Jing Bai, Department of Electrical and Computer Engineering, University of Minnesota-Duluth; Girum Sileshi, Department of Electrical and Computer Engineering, University of Minnesota-Duluth; Glenn Nordehn, Department of Internal Medicine, Midwestern University, Chicago College of Osteopathic Medicine; Stanley Burns, Department of Electrical and Computer Engineering; Lorentz Wittmers, Department of Biomedical Sciences, University of Minnesota-Duluth

15. A 1.2V Comparator for Low Power ADC BioMedical Application Chia-Lin Hu and Ted Higman, Department of Electrical Engineering, University of Minnesota

16. Development of a Reliable and Versatile Photoplethysmograph Device Jami Johnson, Michelle Sabick, Ph.D., Seth Kuhlman, PE, Walt Seale, Ph.D., Department of Mechanical and Biomedical Engineering, Boise State University

17. Using Pressure Transducers for Noninvasive Detection of Heart and Respiratory Rates Matthew R. B. Dowden, Department of Mechanical Engineering, Virginia Tech; Al Wicks, Ph.D., Virginia Tech and Wake Forest University School of Biomedical Engineering and Sciences; Andre Muelenaer, MS, MD, Virginia Tech Carilion School of Medicine Virginia Tech and Wake Forest University School of Biomedical Engineering and Sciences

18. Modeling TETS to Optimize Performance for Ventricular Assist and Artificial Heart Devices V. Bluvshtein MSEE, L. Lucke, Ph.D. EE, Minnetronix, Inc.

19. Cryosurgical Simulations for Ablation Kidney Tumors John Abraham and Josh Jeske, School of Engineering, University of St. Thomas

20. Advanced Epidural Simulator with 3D Flexible Spine and Haptic Interface Neil Vaughan, School of Design, Engineering and Computing Bournemouth University; Venketesh N. Dubey, School of Design, Engineering and Computing Bournemouth University; Michael Y. K.Wee, Poole Hospital NHS Foundation Trust; Richard Isaacs, Poole Hospital NHS Foundation Trust

21. Decomposition of Multichannel Surface EMG Signals Based on Firing Pattern Checking Xiangjun Zhu, Zhijiang College, Zhejiang University of Technology, Department of Urology University of Minnesota; Yingchun Zhang, Department of Urology, University of Minnesota

22. A Framework for Medical Device Design Using CAD Synchronization and Remote High-performance FEA Computing Chi-Lun Lin, Department of Mechanical Engineering, University of Minnesota; Dane Coffey, Department of Computer Science and Engineering, University of Minnesota; Arthur Erdman, Department of Mechanical Engineering, University of Minnesota; Daniel Keefe, Department of Computer Science and Engineering, University of Minnesota

23. Validation Testing and Computational Models for Fatigue Analysis of Medical Devices Kenneth E. Perry, Ph.D., ECHOBIO LLC

24. Evaluate Medical Device Design Robustness by Combining Statistical and Probabilistic tools with Finite Element Analysis Atul Gupta, Endovascular Therapies, Medtronic Inc.; Patrick Koch, Dassault Systemes Simulia Corp.; Xiangyi (Cheryl) Liu, Dassault Systemes Simulia Corp.

25. A Microscale Model for the Mechanical Interaction of Collagen and Fibrin Networks Jeff Hyypio, Mohammad F. Hadi, Victor Lai and Victor H. Barocas, Department of Biomedical Engineering University of Minnesota

26. Simulation of Cutting Force Variation by Finite Element Method Yan Zhuang and Debao Zhou, Department of Mechanical and Industrial Engineering, University of Minnesota

27. Simulation to evaluate alternative approaches to blocking use errors Harold Thimbleby, Abigail Cauchi and Andy Gimblett, College of Science, University of Swansea

28. Use Error Analysis: Toward a Common Language Dean Hooper, Ximedica

29. Case Study on Repeatability of a Threshold-Based Calibration Method for Electrocutaneous Feedback Systems Jan Walter Schroeder, Smart Technology Research Centre, School of Design, Engineering & Computing, Bournemouth University; Venketesh N Dubey, Smart Technology Research Centre, School of Design, Engineering & Computing, Bournemouth University; Tamas Hickish, Smart Technology Research Centre, School of Design, Engineering & Computing, Bournemouth University, Royal Bournemouth Hospital; Jonathan Cole, Smart Technology Research Centre, School of Design, Engineering & Computing, Bournemouth University, Poole Hospital

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Final one-page papers were published in the March 2012 Issue of the ASME Journal of Medical Devices

Scientific Poster Session 1 Continued Wednesday, April 11, 3:30 p.m. - 5:30 p.m.

Hubert H. Humphrey Ballroom, University Hotel Minneapolis30. Design of a Radiolucent Cranial Fixation Device Mary Beth Privitera, M.Design, Bala Haridas, Ph.D., Mario Zuccarello, MD, School of Energy, Environment, Biological and Medical Engineering in partnership with the Department of Neurosurgery, University of Cincinnati

31. Human Factors Validation and Evaluation Testing the Differences and Subsequent Device Design Changes Virginia A. Lang, Ph.D., David M. Hirning, MS, Medical Device Human Factors, HirLan, Inc.

32. Development of Modular Ultrasound Transducer Grips to Reduce Work Related Musculoskeletal Disorders in Sonographers Seth Kuhlman, Center for Orthopaedic and Biomechanics Research, Boise State University; Carly Gerard, Center for Orthopaedic and Biomechanics Research, Boise State University; Brittany Siewert, Center for Orthopaedic and Biomechanics Research, Boise State University; Joie Burns, Department of Radiologic Sciences, Boise State University; Michelle Sabick, Center for Orthopaedic and Biomechanics Research, Boise State University

33. Fetal and Neonatal Heart Rate Monitor for Developing Countries Creighton R Petty, Department of Biomedical Engineering, Johns Hopkins University; Lauren L Smith, Department of Biomedical Engineering, Johns Hopkins University; Geoff R Russel, Department of Biomedical Engineering, Johns Hopkins University; Brian G Rayburn, Department of Biomedical Engineering, Johns Hopkins University; Harshad C Sanghvi, MD, Jhpiego, a Johns Hopkins Affiliate; Soumyadipta Acharya, MD, Ph.D., Department of Biomedical Engineering, Johns Hopkins University

34. Kinematic Control of Biaxial Tissue Testing Apparatus Corbin Reagan , Carl Nelson, Linxia Gu, Department of Mechanical and Materials Engineering; University of Nebraska-Lincoln

35. Perfused Tissue Model for Evaluation of Changes in Bulk Properties James Kennedy, Asad Rauf, Jessica Ashmead, John Lackey and Robert Hitchcock, Department of Bioengineering, University of Utah

36. Sterilization Effects on Rubber Materials Haiying Zhou, Yeng Moua, Ingrid Sayadeth and Tim Reski, Minnesota Rubber & Plastics

37. Portable Pneumatically-Powered Ankle-Foot Orthosis Arthur T. Johnson, Jafar Vossoughi and James Pan, Fischell Department of Bioengineering, University of Maryland

38. Preclinical Creep and Recovery of Absorbable Materials for Medical Devices Maureen L. Dreher, Ph.D. and Danny Hong Srinidhi Nagaraja, Ph.D., Office of Science & Engineering Laboratories, CDRH/FDA

39. Bench Testing of A Powered Transtibial Prosthesis Jinming Sun and Philip A. Voglewede, Department of Mechanical Engineering, Marquette University

40. Silent Aspiration Detection by Using the Sound Analysis Samaneh Sarraf Shirazi and Zahra Moussavi, Department of Electrical and Computer Engineering, University of Manitoba

41. Design and Testing of a Durable Implantable Position Sensor Brian Murphy and John Magill, Physical Sciences Inc.; Roger Kromann and Brent Yates, Embedded Systems Design; Brad Tricomi, Zach Peacock, Maria Papadaki, Maria Troulis, and Leonard Kaban, Massachusetts General Hospital

42. Extremely Simple Constant-gm Technique for Low Voltage Rail-to-Rail Amplifier Input Stage for Portable ECG Boram Lee and Ted Higman, Department of Electrical and Computer Engineering, University of Minnesota

43. Development of a NeuroMechano Stimulator for Rehabilitation of People with Incomplete Spinal Cord Injury Mohammadreza Moravati and Zahra Moussavi, Electrical & Computer Engineering, University of Manitoba

44. Data-Driven Design of a Dexterous Robotic Microsurgery System Frank L. Hammond III, Simon G. Talbot, Robert J. Wood and Robert D. Howe, School of Engineering and Applied Sciences, Harvard University

45. Medical Device for Micro Volume Platelet Separation from Whole Blood Steve Burris, Rochester BioMed LLC; Paul Sadler, Medical Innovations International Inc.

46. Device Time, Data Logging, and Virtual Medical Devices David Arney, Medical Device Plug-and-Play Interoperability Program, CIMIT, Department of Computer and Information Science, University of Pennsylvania; Pratyusha Mattegunta, Medical Device Plug-and-Play Interoperability Program, CIMIT; Andrew King, Department of Computer and Information Science, University of Pennsylvania; Insup Lee, Department of Computer and Information Science, University of Pennsylvania; Soojin Park, Departments of Neurology, Neurosurgery, Anesthesiology and Critical Care, Hospital of the University of Pennsylvania; Margaret Mullen-Fortino, Department of Computer and Information Science, University of Pennsylvania; Julian M. Goldman, Medical Device Plug-and-Play Interoperability Program, CIMIT

47. Development of a Point-of-Care Test for Differential Diagnosis of Fever in Resource-Constrained Settings: The Process Martin Omid Akhavan, Luis Ruben Soenksen, Luccie Wo, Divya Maxwell, James Barger, Soumyadipta Acharya, MD, Ph.D. and Stefan Riedel, MD, Ph.D., Center for Bioengineering Innovation and Design, Department of Biomedical Engineering, Johns Hopkins University

48. Active Implantable Medical Device Reliability Test Methods Bernie Bosley PE, Koumu Engineering, Inc.

49. Dry Gas-Phase Synthesis of Multicomponent Nanoparticles for Cancer Theranostics Pingyan Lei and Steven L. Girshick, Department of Mechanical Engineering, University of Minnesota

50. A Biocompatible Resorbable Microfastening System Maria M. Salamon, Daniel J. Sullivan and John F. Kline, Research Support Instruments

51. Wireless Galvanic Transmission Through Neural Tissue via Modulation of a Carrier Signal by a Passive Probe Andrew E. Papale, Graduate Program in Neuroscience, Univ. Minnesota; Ryan Mork,Dept. Electrical & Computer Engineering, U Minnesota; Chris Boldt, Department of Neuroscience, Univ. Minnesota; Jadin C. Jackson, Department of Biology, University of St. Thomas; John E. Ferguson, Medical Devices Center Fellow, Univ. Minnesota; A. David Redish, Department of Neuroscience, University of Minnesota

52. A Portable Biological Amplifier for Electrovestibulography (EVestG) Chathura Kumaragamage, Brian Lithgow and Zahra Moussavi, Department of Electrical and Computer Engineering, University of Manitoba

53. Virtual Reality Psychophysical Tests to Investigate Human Temporal and Spatial Processing Ability Ahmad Byagowi, Mari T. Garcia Campuzano, Cameron MacGregor and Zahra Moussavi, Department of Electrical and Computer Engineering, University of Manitoba

54. P-300 based Brain-Computer Interface Virtual Keyboard With Predictive Spelling Scott Gavett and Reza Fazel-Rezai, Department of Electrical Engineering, University of North Dakota

55. Evolution of the cost-effectiveness of Endovascular and Open Surgical Repair of Abdominal Aortic Aneurysms Isa C.T. Santos, Faculdade de Engenharia, Universidade do Porto; G. Scott Gazelle, Institute for Technology Assessment and Department of Radiology, Massachusetts General Hospital; Luís A. Rocha, Institute for Polymers and Composites/I3N, University of Minho; João Manuel RS Tavares, Faculdade de Engenharia, Universidade do Porto

56. Reducing Urinary Tract Infections with Superhydrophobic-Textile-Lined Catheters Tsung-chow Su, Department of Ocean & Mechanical Engineering, Florida Atlantic University; Gajanan Bhat, Materials Science & Engineering, University of Tennessee, Department of Ocean & Mechanical Engineering, Florida Atlantic University

57. Design of an Elastomeric Tubular Osmotic Pump for Intravesical Delivery of Lidocaine to the Bladder Heejin Lee, TARIS Biomedical, Department of Mechanical Engineering, Massachusetts Institute of Technology; Michael J. Cima, Department of Materials Science & Engineering, Koch Institute of Integrative Cancer Research, Massachusetts Institute of Technology

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Scientific Poster Session 2Thursday, April 12, 2:00 p.m. - 3:30 p.m.



1. Mercury Boot: A Way to Speed Recovery and Reduce Vascular Complications from Lower Extremity Surgery or Trauma Dawn Bardot, Gwenyth Fischer, Michael Dahl and Kiyoyuki Miyasaka, Senior Innovation Fellows Emeritus, Medical Devices Center, University of Minnesota

2. Analytical and Numerical Evaluation of an Improved Adjustable Bone Plate for Mandibular Fracture Repair Thomas M. Cervantes, Department of Mechanical Engineering, Massachusetts Institute of Technology; Alexander H. Slocum, Jr., Department of Mechanical Engineering, Massachusetts Institute of Technology; Joan C. Edwards School of Medicine, Marshall University; Edward B. Seldin, DMD, MD, Department of Oral and Maxillofacial Surgery, Massachusetts, General Hospital

3. Device to Assist Force Generation in High-load Orthopedic Actions Roel F.P. van Gorkum, Department of Biomechanical Engineering, Faculty of Mechanical, Maritime and Materials Engineering, Delft University of Technology; Jenny Dankelman, Department of Biomechanical Engineering, Faculty of Mechanical, Maritime and Materials Engineering, Delft University of Technology; Gabriëlle J.M. Tuijtho, Department of Biomechanical Engineering, Faculty of Mechanical, Maritime and Materials Engineering, Delft University of Technology, Department of Orthopedic Surgery, Academic Medical Centre

4. Biomechanics for Appropriate Sizing of Cervical Arthroplasty Hitesh Mehta, Ed Santos, Arin Ellingson and David Nuckley, Department of Biomedical Engineering, Department of Orthopaedic Surgery, University of Minnesota

5. Development and Validation of a Force Sensing Probe for Improved Accuracy of Spinal Surgery David J. Nuckley, David W. Polly, Jr., Tim Pommer and Arthur Erdman, Departments of Physical Medicine and Rehabilitation, Orthopaedic Surgery, and Mechanical Engineering, University of Minnesota

6. Next generation of a non-invasive-stimulated Muscle Force Assessment System to Study the ICU Patient Hans F. Ginz, Paul A. Iaizzo and William K. Durfee, Department of Anaesthesia, County Hospital Loerrach; Department of Anaesthesia, University Hospital, Basel; Departments of Surgery and Mechanical Engineering, University of Minnesota

7. Differential Spring Stiffness Design for Finger Therapy Exercise Device: Bio-inspired from Stiff Pathological Finger Joints Chen-Hua Yeow, School of Engineering and Applied Sciences, Harvard University, Department of Bioengineering, National University of Singapore; Andrew Baisch, School of Engineering and Applied Sciences, Harvard University; Robert Howe, School of Engineering and Applied Sciences, Harvard University; Simon Talbot, Department of Plastic Surgery, Brigham and Women’s Hospital; Conor Walsh, School of Engineering and Applied Sciences, Harvard University, Wyss Institute for Biologically Inspired Engineering, Harvard University

8. Hydraulic Ankle Foot Orthosis Jicheng Xia, Katherine Houle, Connor Mulcahy, and William Durfee, Department of Mechanical Engineering, University of Minnesota

9. Design and Initial Testing of a Hybrid FES Gait-Assist System Brenton Steinmann, Virinchi Mallela and William Durfee, Department of Mechanical Engineering, University of Minnesota

10. Mimetic Jar Device Capable of Measuring Dynamic Opening Forces: Development and Validation Arin M. Ellingson, Michelle Ferkel, Corey McGee and David J. Nuckley, Musculoskeletal Biomechanics Laboratory, University of Minnesota

11. Calibration of an Airflow Perturbation Device (APD) Arthur T. Johnson, Jafar Vossoughi and James Pan, Fischell Department of Bioengineering, University of Maryland

12. Stiffness Softening in Body Powered Hand Prosthesis Lodewijk Kluit, The Hague University, Academy for Technology, Innovation & Society; Nima Tolou, Delft University of Technology, Department of Biomedical Engineering; David Tiemens, The Hague University, Academy for Technology, Innovation & Society; Just Harder, Delft University of Technology, Department of Biomedical Engineering

13. Wearable Electrocutaneous Feed-back System: A Smart Device to Compensate for Sensation Loss Jan Walter Schroeder, Smart Technology Research Centre, School of Design, Engineering & Computing, Bournemouth University; Venketesh N Dubey, Smart Technology Research Centre, School of Design, Engineering & Computing, Bournemouth University; Tamas Hickish, Smart Technology Research Centre, School of Design, Engineering & Computing, Bournemouth University, Royal Bournemouth Hospital; Jonathan Cole, Smart Technology Research Centre, School of Design, Engineering & Computing, Bournemouth University, Poole Hospital

14. Adjustable stiffness guide catheter for intracranial intervention Devesh Amatya, Ph.D., Glenn Walker, Ph.D., Department of Biomedical Engineering, North Carolina State University; Ravish Sachar, MD, Wake Medical Center

15. Design of a Bi-Corporal Pump for the Treatment of Hydrocephalus Deric Cole, Shavonna Warren, Brian Kroeter, Michael Flatt, Kalyani Nair, Martin Morris, and Julian Lin, Department of Mechanical Engineering, Bradley University

16. The Effects of Tongue Position Corrective Device for Obstructive Sleep Apnea Syndrome in China Yueyang Chen, BS, College of Biological Sciences, University of Minnesota-Twin Cities; Haidong Chen, DDS, MS, Shanghai Guang Ren Anti-Snoring Health Center

17. Position of a Needle Tip Estimated with Fiber Bragg Gratings Kirsten Henken, Jenny Dankelman and John van den Dobbelsteen, Biomechanical Engineering, Delft University of Technology

18. Test Set-up to Study the Behavior of a Flexible Instrument in a Bent Tube Jitendra P. Khatait, Dannis M. Brouwer Ronald G.K.M. Aarts and Just L. Herder, Mechanical Automation & Mechatronics, University of Twente, the Netherlands

19. Measuring Force and Fluid Pressure during Epidural Needle Insertion Dennis J. van Gerwen and John J. van den Dobbelsteen, Department of Biomechanical Engineering, Delft University of Technology

20. Economical Communication Device for Persons with Disabilities Andrew Kapraun, Kyle Heaton and Jodi Prosise, Ph.D., Industrial Engineering, St. Ambrose University; MaryAnne Haslow-Hall, Elizabeth Wilson, Liz Koslow, Hank Yochum, Ph.D. and Scott Pierce, Ph.D., Engineering Science, Sweet Briar College

21. Modular Joystick Design for VR Surgical Skills Training Michael Head, Dept. of Mechanical and Materials Engineering; University of Nebraska-Lincoln; Carl A. Nelson, Dept. of Mechanical and Materials Engineering; University of Nebraska-Lincoln; Ka-Chun Siu, Dept. of Environmental, Agricultural, & Occupational Health; Univ. of Nebraska Medical Center

22. Evaluation Of Active Colonoscopy Training Model Ravindra V. Kale, Department of Mechanical Engineering; JungHun Choi, Department of Mechanical Engineering; David Drozek, College of Osteopathic Medicine, Ohio University

23. An Organ Positioner to Mitigate Collateral Tissue Damage in Esophagus during Atrial Fibrilation Walter Anderson, Ahmadreza Eshghinejad and Mohammad Elahinia, Nitinol Commercialization Accelerator, Department of Mechanical Engineering, University of Toledo

24. A Socially Assistive Robot for Meal-Time Cognitive Interventions Derek McColl, Department of Mechanical and Industrial Engineering, University of Toronto; Jeanie Chan, Department of Mechanical and Industrial Engineering, University of Toronto; Goldie Nejat, Department of Mechanical and Industrial Engineering, University of Toronto and Toronto Rehabilitation Institute

25. Cognitive and Physical Assistance for the Elderly in Kitchen Environments Maurizio Ficocelli, Department of Mechanical and Industrial Engineering, University of Toronto; Goldie Nejat, Department of Mechanical and Industrial Engineering, University of Toronto and Toronto Rehabilitation Institute

26. The Feasibility of Implanting a Microphone into Mouthguards for Sleep Apnea Assessment Udeesha Annakkage, Department of Electrical and Computer Engineering, University of Manitoba; Ali Azarbarzin, Department of Electrical and Computer Engineering, University of Manitoba, Ehealth, TRLabs; Zahra Moussavi, Department of Electrical and Computer Engineering, University of Manitoba, Ehealth, TRLabs, Riverview Health Center

27. Design, Development, and Validation of KIDS-CRRT - A Safe and Accurate Pediatric Continuous Renal Replacement Device Arvind Santhanakrishnan, Department of Biomedical Engineering, Georgia Institute of Technology & Emory University; Trent Nestle, Department of Biomedical Engineering, Georgia Institute of Technology & Emory University; Brian L. Moore, Emory University School of Medicine; Ajit P. Yoganathan, Department of Biomedical Engineering, Georgia Institute of Technology & Emory University; Matthew L. Paden, Division of Pediatric Critical Care, Emory University & Children’s Healthcare of Atlanta

28. Management of Postpartum Hemorrhage in the Developing World Adam J. Clark, Anastasia V. Borok, Luke T. Jungles and Nathaniel C. Moller, Center for Bioengineering Innovation and Design, Department of Biomedical Engineering, Johns Hopkins University

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Scientific Poster Session 2 ContinuedThursday, April 12, 2:00 p.m. - 3:30 p.m.


29. Cost-Effective Diagnosis of Pneumonia Raymond L. Watrous and Daniel K. Bogen, Departments of Electrical/Systems and Bioengineering, University of Pennsylvania

30. Hand-held Ultrasound Device for Dialysis Vascular Access Volume Flow Monitoring Grant H. Kruger, Department of Engineering; Robert E. Dodde, Department of Internal Medicine; Brian Thelen, Department of Statistics; William F. Weitzel, Department of Internal Medicine, University of Michiga

31. Percutaneous Biopsy Device Design with Haemostatic Bleeding Control Grant H. Kruger, Department of Engineering; William F. Weitzel, Department of Internal Medicine, University of Michigan

32. Alternative Sterilization Method for Heat Sensitive Products with Safe Residual Components Kristy Yates, Research Associate, Jon Olson, Microbiology Manager, Alan Au, Senior Product Manager, Tom Gentle, Director of Research & Development, Minntech Corp.

33. An Acoustic Sensor for Airflow in Pediatric Artificial Airways Thomas Ruscher, Department of Mechanical Engineering, Virginia Tech University; Al Wicks, Ph.D., Department of Mechanical Engineering, Virginia Tech, Virginia Tech-Wake Forest School of Biomedical Engineering and Sciences; Andre Muelenaer, MS, MD, Virginia Tech Carilion School of Medicine Virginia Tech-Wake Forest School of Biomedical Engineering and Sciences, Pediatric Medical Device Institute; Joseph Tamez, MD, Carilion Clinic

34. Material Handling System for Robotic NOTES: Open Loop Control & In Vivo Results Jeff Midday, Dept. of Mechanical & Materials Engineering, University of Nebraska–Lincoln; Carl Nelson, Dept. of Mechanical & Materials Engineering, University of Nebraska–Lincoln and Dept. of Surgery, Univ. of Nebraska Medical Center; Dmitry Oleynikov, Dept. of Surgery, Univ. of Nebraska Medical Center

35. Novel Pan-Tilt Stereoscopic Camera with Auto-Focus for LESS Robotic Surgery Eric J. Markvicka, Department of Mechanical and Materials Engineering University of Nebraska-Lincoln; Jack M. Mondry, Department of Mechanical and Materials Engineering, University of Nebraska-Lincoln; Shane M. Farritor Department of Mechanical and Materials Engineering, University of Nebraska-Lincoln; Dmitry Oleynikov, Department of Surgery, University of Nebraska Medical Center

36. Cranial Drilling Tool with Retracting Drill Bit Upon Skull Penetration Paul Loschak, Harvard School of Engineering and Applied Science Harvard University; Kechao Xiao, Harvard School of Engineering and Applied Science, Harvard University; Hao Pei, Harvard School of Engineering and Applied Science Harvard University, Wyss Institute for Biologically Inspired Engineering, Harvard University; Samuel B. Kesner, Harvard School of Engineering and Applied Science, Harvard University; Ajith J. Thomas, MD, Beth Israel Deaconess Medical Center; Conor Walsh, Ph.D., Harvard School of Engineering and Applied Science, Harvard University, Wyss Institute for Biologically Inspired Engineering, Harvard University

37. The MSIS Trocar: An Isolator System for Laparoscopic Surgery. Tim Horeman, FW Jansen and J Dankelman, Delft University of Technology, The Netherlands

38. Laparoscopic Simulation Device for Testing and Training Caroline Flowers, Nikolai Begg and Alexander Slocum, Department of Mechanical Engineering, Massachusetts Institute of Technology

39. Multi-Angle Rear-Viewing Endoscopic Tool (MARVEL) for Minimally Invasive Neurosurgeries Michael Shearn, Jet Propulsion Laboratory, California Institute of Technology; Sam Y. Bae, Jet Propulsion Laboratory, California Institute of Technology; Ron Korniski, Jet Propulsion Laboratory, California Institute of Technology; Harish Manohara, Jet Propulsion Laboratory, California Institute of Technology; Jack Mondry, University of Nebraska; Hrayr Shahinian, Skull Base Institute

40. Design and Development of a Novel Puncture Access Device Nikolai Begg, Department of Mechanical Engineering, Massachusetts Institute of Technology

41. Design of an Atraumatic Compliant Surgical Grasper Alan Goyzueta and Carl A. Nelson, Dept. of Mechanical & Materials Engineering, University of Nebraska–Lincoln

42. Mechanical Abdominal Wall Lifting Device for Laparoscopic Surgery Jared Ostdiek and Carl A. Nelson, Dept. of Mechanical & Materials Engineering, University of Nebraska-Lincoln

43. Analysis of the Looping Problems in Colonoscopy Using Bending Sensors JungHun Choi, Ph.D., Department of Mechanical Engineering/ Biomedical Engineering Program, Ohio University; David Drozek, D.O., College of Osteopathic Medicine, Department of Specialty Medicine, Ohio University

44. A Review to the Powered Drilling Devices for Craniotomy Ming-Huei Hsiao and Chin-Hsing Kuo, Department of Mechanical Engineering, National Taiwan University of Science and Technology

45. Variable Assessment for Design Monopolar Hot Biopsy Forceps Randy Robert, Department of Mechanical Engineering, Ohio University; Liang Chen, Biomedical Engineering Program, Ohio University; JungHun Choi, Department of Mechanical Engineering, Biomedical Engineering Program, Ohio University; David Drozek, Department of Specialty Medicine, Ohio University

46. A Robot Calibration Method for Minimally Invasive Surgery Songpo Li and Xiaoli Zhang, Department of Engineering and Physics, Wilkes University; Carl A. Nelson, Department of Mechanical and Materials Engineering, University of Nebraska-Lincoln

47. Efficient Motor Control for Handheld Surgical Devices V. Bluvshtein, MSEE and L. Lucke, Ph.D. EE, Minnetronix, Inc.

48. Non-Thermal Destruction of Prostate Cancer by Irreversible Electroporatioin Chunlan Jiang, Zhenpeng Qin, and John Bischof, Department of Mechanical Engineering, University of Minnesota; Gary Long, Ethicon Endo-Surgery, Inc

49. Precision Pneumatic Robot for MRI-Guided Neurosurgery David B. Comber, Diana Cardona, Robert J. Webster, Ph.D., and Eric J. Barth, Ph.D., Department of Mechanical Engineering, Vanderbilt University

50. Manual Active Cannula Deployment: Experimental Accuracy Evaluation in Free Space Marlena S. Clark, Jessica Burgner, Philip J. Swaney, and Robert J. Webster III, Department of Mechanical Engineering, Vanderbilt University

51. Electro Thermomechanical Behavior of a Smart Actuator for an Active Surgical Needle Naresh V. Datla, Department of Mechanical Engineering, Temple University; Mohammad Honarvar, Department of Mechanical Engineering, Temple University; Tuan M. Nguyen, Department of Mechanical Engineering, Temple University; Tarun K. Podder, Department of Radiation Oncology, East Carolina University; Yan Yu, Department of Radiation Oncology, Thomas Jefferson University; Adam P. Dicker, Department of Radiation Oncology, Thomas Jefferson University; Kurosh Darvish, Department of Mechanical Engineering, Temple University; Parsaoran Hutapea, Department of Mechanical Engineering, Temple University

52. Mechanical Characterization of Prostate Tissue-Mimicking Phantoms for the Development of an Active Surgical Needle Naresh V. Datla, Department of Mechanical Engineering, Temple University; Jing Y. Koo, Department of Mechanical Engineering, Temple University; Daniel J.W. Choi, Department of Mechanical Engineering, Temple University; Soroush Assari, Department of Mechanical Engineering, Temple University; Ali Hemmasizadeh, Department of Mechanical Engineering, Temple University; Tarun K. Podder, Department of Radiation Oncology, East Carolina University; Yan Yu, Department of Radiation Oncology, Thomas Jefferson University; Adam P. Dicker, Department of Radiation Oncology, Thomas Jefferson University; Kurosh Darvish, Department of Mechanical Engineering, Temple University; Parsaoran Hutapea, Department of Mechanical Engineering, Temple University

53. Magnetic Mechanism for Wireless Capsule Biopsy Massimiliano Simi, The BioRobotics Institute, Scuola Superiore Sant’Anna, Pisa, Italy and STORM Lab, Mechanical Engineering Department, Vanderbilt University; Giada Gerbonia, The BioRobotics Institute, Scuola Superiore Sant’Anna, Pisa, Italy; Arianna Menciassia, The BioRobotics Institute, Scuola Superiore Sant’Anna, Pisa, Italy; Pietro Valdastrib, STORM Lab, Mechanical Engineering Department, Vanderbilt University

54. HepatoSeal - Multimodal Mono-Bipolar Device for Liver Resection SurgeryScott Bala Haridas and Mary Beth Privitera, M.Design, School of Energy, Environment, Biological and Medical Engineering, University of Cincinnati Steven M Rudich, MD, Ph.D.., Department of Surgery, University of Cincinnati

55. Zero Drift Linerity Characterization of a Wireless Pressure Sensor Tanner Coleman, Sean Maass and Robert Hitchcock, University of Utah Department of Bioengineering

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2012 Contributed Papers Committee MembersCardiovascularMichael Eggen Medtronic, Inc. Jason Quill Medtronic, Inc. James St. Louis University of MinnesotaAlena Talkachova University of MinnesotaNeuroengineering Marom Bikson City University of New YorkSilvestro Micera Scuola Superiora Sant’Anna, Pisa, ItalyOrthopedicsJoan Bechtold Minneapolis Medical Research FoundationGabrielle Tuijthof Delft University of Technology, NLUrologicJong Yoon Qatar University, QatarRehabilitationVenkatesh Dubey Bournemouth University, UKAndrew H. Hansen Northwestern UniversityEngineered TissuesJan Herman Kuiper Keele University, UKMEMS and NanoJust Herder Delft University of Technology, NLSurgical ToolsPaul Breedveld Delft university of Technology, NLCarl Nelson University of Nebraska-LincolnAlexander Slocum Massachussetts Institute of TechnologyComputer Modeling and SimulationJohn van den Dobbelsteen Delft University of Technology, NLYunhe Shen University of MinnesotaDesign and Human FactorsKathleen Harder University of MinnesotaMedical Device Product Development ProcessMary Beth Privitera University of CincinnatiEdsko Hekman University of TwenteRegulatory and IPDap Hartmann Delft University of Technology, NLSpecial Devices Chin Hsing Kuo National Taiwan University of Science and

TechnologyGoldie Nejat University of Toronto, CanadaKathleen Sienko University of MichiganXiaoli Zhang Wilkes University

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2012 Technical Organizing CommitteeTaner Akkin Neuroengineering 1: NeuroimagingVictor Barocas Computer-Aided Design of Medical DevicesJoan Bechtold Orthopedics: 3 R’s - Research, Regulatory and ReimbursementJohn Bischof Cardiovascular 5: Cardiac Ablative Therapies

Laser Therapies: Treatments for Cancer and DiseaseLarry Carrier Cardiovascular 2: Pre-Clinical Testing of Novel Cardiovascular DevicesTianhong Cui Micro & Nano Devices 3Afshin Divani Neuroendovascular Devices for Treating Stroke and Vascular MalformationRalph Hall FDA Innovation InitiativeAndrew Hansen Prosthetics and OrthoticsKathleen Harder Human Factors 1Bin He Cardiovascular 4: Cardiac Electrophysiology and MappingJust Herder Contributed Papers 1

Contributed Papers 2Rehabilitation Robotics

Alex Hill Cardiovascular 3: Cardiac ModelingPaul Iaizzo Cardiovascular 1: Cardiac Keynotes

Cardiovascular 5: Cardiac Ablative TherapiesMatt Johnson Neuroengineering 3: Closed-Loop NeuromodulationKaren Kaehler EntrepreneurshipDan Keefe Symposium Chair “Virtual Prototyping of Medical Devices”Tim Kowalewski Surgical RoboticsJeremy Lenz What’s New in Minnesota to Support the Medical Device IndustryHugh Lim Neuroengineering 4: New Advances in Electrode TechnologiesTay Netoff Neuroengineering 2Sang-Hyun Oh Micro & Nano Devices 2Steve Parente Valuing Early and Global Medical Technology within a UniversitySaurav Paul Medical Device Innovation

Three-in-Five CompetitionMary Beth Privitera Medical Device DesignLeon Radziemski Power for Implanted Medical DevicesRajesh Rajamani Micro & Nano Devices 1

Power for Implanted Medical DevicesKathleen Sienko Design for Global HealthJames St. Louis Cardiovascular 6: Cardiac Devices in the Pediatric PopulationRick Stein Human Factors 2: Usability of Remote Controlled Medical DevicesBob Tranquillo Engineered Tissues

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2012 Design of Medical Devices 5K Fun Run/WalkMonday, April 9, 7:00 p.m.

The University of Minnesota Medical Device 2011-2012 Fellows and 2012 Design of Medical Devices Conference would like to thank all of the runners and walkers that participated in the Fourth Annual 5K Fun Run/Walk, Monday, April 9, at the University of Minnesota Campus.

Please join us next year for the Fifth Annual 5K Fun Run/Walk, Monday, April 8, at the University of Minnesota Campus.

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2012 DMD Conference Planning Committee: John Bischof, Conference Co-Chair Alyssa Davidson, Conference Coordinator William Durfee, Conference Co-Chair Arthur Erdman, Conference Chair Just Herder, Contributed Papers Chair Jenny Holden, Conference Administrator Paul Iaizzo, Conference Co-Chair Trisha Johnson, Conference Coordinator Saurav Paul, Conference Co-Chair Gary Williams, AV Technical Specialist

International Advisory Board: Just L. Herder Delft University of Technology, The Netherlands

Special thanks to: American Society of Mechanical Engineers BioBusiness Alliance of Minnesota Conference Volunteers Corey Benson and Staff D’Amico Catering Department of Biomedical Engineering, University of Minnesota Institute for Engineering in Medicine, University of Minnesota James McCabe Photography and Printing LifeScience Alley McNamara Almuni Center Office of Business Relations, University of Minnesota The University Hotel Minneapolis

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