Diseases of Salivary Glands Lab
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Transcript of Diseases of Salivary Glands Lab
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Diseases Of Salivary Glands
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This histological section
is taken from one of the
major salivary glands
1- What is the type of
Acini present?!
2- What is the most
3- Through what duct
this gland drains its
saliva into the oral
cavity?!
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This histological section
is taken from one of the
major salivary glands
1- What is the type of
Acini present?!
2- What is the most
3- Through what duct
this gland drains its
saliva into the oral
cavity?!
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7/30/2019 Diseases of Salivary Glands Lab
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This histological section
is taken from one of the
major salivary glands
1- What is the type of
Acini present?!
2- What is the most
3- Through what duct
this gland drains its
saliva into the oral
cavity?!
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These clinical pictures
show the various
locations of minor
salivary glands in the
oral cavity
1- What is the type of
Acini present?!
2- Name threedifferent locations
where such glands
cant be found?!
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This 50 years old female is presented
to the clinic for routine dental
examinationunilateral mildlyUpon examination,
tender swelling of the submandibular
is foundgland region
This is the result of the biopsy done!
1- What is the most likely diagnosis?!
- a a cau uc
condition?!
3- What in the history of the patient might
confirm diagnosis?!
4- Of the major salivary glands, which is
more commonly involved?!
5- Whats the best tool to diagnose duct
obstruction and glandular tissuedestruction in this condition?!
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Give me 3
differentialdiagnoses for
this
histologicalappearance!!
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This histological section from one
of the major salivary glands was
sent to you to reach definitivediagnosis
1- Describe this histological
appearance?!
2- What is the most likely diagnosis?!
3- What is the main cause behind such
condition?!
4- What is the structure represented by
the circle?!
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This 45 years old female is presented
to the clinic for routine dental
examinationbilateral painlessUpon examination,
isswelling of the parotid gland region
found
This is the result of the biopsy done!
1- What is the most likely diagnosis?!
- a cau co o
3- Of the salivary glands, which are more
commonly involved?!
4- When lacrimal glands are also involved,
then the condition is?!
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Non-caseating
granuloma
(macrophages)
SarcoidosisLymphocytes
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This 30 years old female is presented
to the clinic for routine dental
examinationthis yellowishUpon examination,
discoloration of the orifice of
Wharton's duct was noticed
This is the result of the biopsy done!
1- What is the most likely diagnosis?!
- a va y a , w c a o
commonly involved?!
3- What are the clinical features of this
condition?!
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Sialolith
Hyperplasticductal
epithelium
Salivary Calculus (Sialolith)
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This 30 years old male is
presented to the clinic for
consultationtwo deepUpon examination,
like ulcers were found on-crater
the hard palate
The patient states that theseulcers were just a swelling one
week ago
done!
1- What is the most likely diagnosis?!
2- What causes this condition?!
3- What is the clinical and histological
differential diagnosis for such
ulcers?!?!
4- Whats your management?!
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Lobular Necrosis Sequamous Metaplasia
Necrotizing Sialometaplasia
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Necrotizing Sialometaplasia
May start as small ulcerMay start as indurated swelling
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This 65 years old male is
presented to the clinic for
consultationoralUpon examination,
tissues looked dry,
smooth and glazed and
the tongue lookedatrophic, fissured and
Lobulated
dry gritty eyes
1- What is the cause of this
intraoral finding?!
2- What is the cause of this
ophthalmic finding?!
3- What is the most likely
diagnosis?!
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This 65 years old male is
presented to the clinic for
consultationoralUpon examination,
tissues looked dry, smooth
and glazed and the tongue
looked atrophic, fissured andLobulated
dryPatient complains from
1- Into how many categories this
condition is classified?!
rheumatoidIf this patient has-2
, then to what category youarthritis
can relate him?!
3- What are the components of the
European criteria to reach the finaldiagnosis?!
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This 65 years old male is presented to
the clinic for consultation
oral tissues lookedUpon examination,dry, smooth and glazed and the tongue
looked atrophic, fissured and
Lobulated
dry gritty eyesPatient complains from
1- Whom are mainly affected: males or
females?!
2- Into which category, oral and ocularsymptoms are more severe?!
3- What are the most important histological
features seen?!
4- What are the most important
investigatory methods?!
5- What is the most important
complication?!
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Lymphocytic infiltration
Sjgren syndrome
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Sjgren syndrome
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Snowstorm or cherry tree in blossom
Sjgren syndrome
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This 40 years old male is presented
to the clinic for consultation
Upon examination, Slowly growing,painless, rubbery swelling with
intact overlying skin or mucosa is
present
Patient is aware of lesion forseveral years
This is the result for the biopsy
1- What is the most likely diagnosis?!
2- Of the salivary glands, which is more
commonly involved?!?!
3- What are the most important
histological features seen?!
4- What is the best treatment option and
why?!
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Pleomorphic adenoma
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Pleomorphic adenoma
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Pleomorphic adenoma
Hyalinization Chondroid
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Keratin pearl
Pleomorphic adenoma
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This 50 years old male is presented
to the clinic for consultation
Upon examination, Slowly growing,
painless, rubbery swelling is
present
Patient is aware of lesion for
several years
This is the result for the biopsy
done!
1- What is the most likely diagnosis?!
2- What are the most important
histological features seen?!
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Warthin Tumor
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These histological sections were
sent to you to reach final diagnosis
1- What is the most likely diagnosis?!
2- What are the most important
histological features seen?!
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Canalicular adenoma
This 30 years old male is presented
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This 30 years old male is presented
to the clinic for consultation
Upon examination, Slowly growing,painless, rubbery swelling with
intact overlying skin or mucosa is
present
1- Give me 2 clinical differential
diagnoses?!
- ccor ng to t e sto og ca eatures,
what is the most likely diagnosis?!
2- Of the salivary glands, which is more
commonly involved?!?!
3- What are the most importanthistological features seen?!
4- What are the characteristic features of
low and high grade variants of the
condition?!
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Intermediatecells
Mucous cells Epidermoid cells
Mucoepidermoid
carcinoma
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High grade
Mucoepidermoid
carcinoma
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MucoepidermoidDifferentiation between High grade
carcinoma and Sequamous cell carcinoma through PAS stain
This 30 years old male is
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y
presented to the clinic for
consultationUpon examination, this oral
ulceration is seen
1- Give me 3 clinical differential
diagnoses?!
2- According to the histological
,
diagnosis?!
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These histological sections were
sent to you to reach final diagnosis
facialThe patient is present with
palsy and neurological
onsmanifestati
1- What is the most likely diagnosis?!
2- What are the most important histological
features seen?!
3- Is radiotherapy an acceptable treatment?!
4- Which carry better prognosis: cribriform or
solid types?!