DigiSight Technologies
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Transcript of DigiSight Technologies
Our Mission:
To integrate mobile-diagnostics into clinical care.
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DigiSight Integrates mHealth Data
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H Confidential
DigiSight Works With 13 Ophthalmic Tests Today
Test Mobile Technology
1) Visual acuity (Snellen near-vision equivalent) Mobile application
2) Amsler/Metamorphopsia Mobile application
3) Low light acuity Mobile application
4) Inverse acuity Mobile application
5) Contrast sensitivity Mobile application
6) Inverse contrast Mobile application
7) Low light contrast Mobile application
8) Color discrimination Mobile application
9) Acuity + contrast Mobile application
10) DigiGrid proprietary acuity Mobile application
11) Fundus images (in development) Smartphone Add-on
12) Anterior segment imaging (in development) Smartphone Add-on
13) Continuous IOP (in development) Implantable Device
3 Confidential
The Product: Single, Secure Portal for mHealth
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• Single Portal unites data feeds from multiple diagnostics to create a complete clinical view of patients
• Physician-friendly interface for patient examinations
• Data automatically linked to physician portal through cloud architecture
• Data is transmitted securely and in HIPAA-compliant way
• Creates comprehensive data-analytics by integrating all diagnostics Confidential
Use Cases Benefit Clinical Care And Financial Performance
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DigiSight
Platform
Financial/Workflow
Clinical Care
Research
Commercial
6 17 October 2014
Case Study: High Frequency Monitoring
Completed Clinical Studies to Date
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Name Title Location Sponsor
NEI Intravitreal Ranibizumab For Neovascular AMD: Treat And Extend Vs. Monthly Exams With PRN Therapy
Multiple sites NEI Genentech
LIBERTY A Clinical Trial To Assess The Impact Of Home Monitoring To Decrease The Treatment Burden For Neovascular Macular Degeneration
Retinal Consultants of Arizona (Phoenix, AZ)
Genentech
Diabetic Screening
Camera Phone Telemedicine-based Screening for Diabetic Eye Disease
SCVMC (Santa Clara, CA)
Completed
UCLA Use Of A Mobile Internet Application To Increase Communication Among The Diabetic Patient, Diabetologist And Ophthalmologist
Jules Stein Eye Institute (Los Angeles, CA)
UCLA
Kyung Hee University
Reliability Of The Smartphone-based Electronic Visual Acuity Testing; Applications In Remote Monitoring And Clinical Research Of Macular Pathology
Kyung Hee University (Seoul, Korea)
Kyung Hee University
CPMC Relationship between standard Snellen visual acuity and various tests of near VA
CPMC (San Francisco, CA)
DigiSight
Confidential
Clinical and Pilot Trial Partners
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Ophthalmology Is A Great Place To Start
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Concentrated Specialty
• 15,000 ophthalmologists in US • Diagnose, treat, follow patients • Efficient decision making process • Focused adoption strategy
Mobile Is Good For Ophth Dx
• Many diagnostics are mobile-friendly (eg - VA, Amsler, micro-perrimetry, IOP, refractive error)
Large & Motivated Patient Populations
• 30 million patients with AMD, DR, Glaucoma or Cataracts
• Loss of sight is one of most feared conditions and is chronic
• Neurological conditions diagnosed in part by ocular tests
Important Outcomes
• Blindness is expensive and a major cost for payers and society
Confidential
Large Patient Populations
Retinitis Pigmentosa
Retinal Vein Occlusion
AMD
Trauma
Glaucoma
DR/DME
Dry AMD
- 2.0 4.0 6.0 8.0 10.0 12.0 US Patients (MM)
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Team
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Name Past Companies Domain Experience
Doug Foster CEO
Robertson, Stephens Inc., Pequot Capital, Longitude Capital
• Medical device commercialization
• Finance
Alison Polkinhorne Vice President Product
Sun Microsystems, Ardent, Ipsilon, NVidia • Product management • UI/UX development
Doug Merrell Chief Software Architect
DuPont Company, VI Laboratories, Ardent
• Software engineering
Ed Kanner Vice President Finance
Ernst & Young LLC, Sanderling Ventures LLC, NEKTAR Therapeutics
• Finance • Human resources
Ritu Tandon Senior Business Manager
STEM Leadership, Education Pioneers • Product management
Jin Li iOS Engineer
IGT, Lucid Design, Reality Digital, Cengage Learning
• Software engineering
Mike Terry Consultant
Raytheon • Software engineering
>150 years experience with platform systems and healthcare ventures
Scientific Advisory Board Phil Rosenfeld, MD, PhD Bascom Palmer Eye Institute Miami, FL
Pravin Dugel, MD Retinal Consultants of Arizona Phoenix, AZ
George Williams, MD William Beaumont Hospital Detroit, MI
Larry Singerman, MD Retina Associates of Cleveland Cleveland, OH
Jeffrey Heier, MD Ophthalmic Consultants of Boston Boston, MA
David Boyer, MD Retina Vitreous Associates Los Angeles, CA
K. Bailey Freund, MD VRM Consultants New York, NY
Anne Fung, MD Genentech San Francisco, CA
Neil Friedman, MD Mid-Peninsula Ophthalmology Palo Alto, CA
Allen Ho, MD Mid Atlantic Retina Philadelphia, PA
David Brown, MD Retina Consultants Houston Houston, TX
Peter Kaiser, MD Cleveland Clinic Cleveland, OH
Michael Trese, MD William Beaumont Hospital Detroit, MI
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Conclusion
" Clear Strategy: Be the leading mHealth company for ophthalmology, then expand into other specialties
" Large Market: Over 30mm patients with acute ophthalmic conditions
" Unmet Need: mDx do not integrate into clinical practice; healthcare benefits from integrated data
" Expert Team: Medical device experience, software experience, and the world’s leading ophthalmologists
" Traction: DigiSight integrates 13 tests, used in multiple studies and by major pharma
13 Confidential