Dietary Modification in Various Imbalance of Endocrine Production

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    DIETARY MODIFICATION IN VARIOUS IMBALANCE OF

    ENDOCRINE PRODUCTION

    ( dr. Dimyati Burhanuddin, Msc)

    The Deviation of normal metabolic pathway, result to

    Abnormal production of one or more hormones

    Deficiency of an enzymes

    Modification of ecretion

    ! effect the balance of endocrine production

    !diseases

    "ypo#lycemia ! shoc$ (insuline shoc$)

    %aused by &

    'nsuline overdose

    Decrease of available #lucose

    o food

    oss of food

    *ver eercise

    +pontaneous hypo#lycemia disorder of carbohydrate metabolism ( functional, or#anic)

    'n functional hyperinsulinism ! stimulative type of hypo#lycemia ( no or#anic lesion )

    %arbohydrate islet cells (hi#h respons)

    "yperinsulinism

    "ypo#lycemia

    -

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    'n or#anic lesion (post #astro intestimal operation)

    %arbohydrate

    di#estion

    rapid #lucose absorption

    sudden elevation of blood #lucose

    islet cells

    hyperinsulinism

    hypo#lycemia

    Dietary principle

    carbohydrate & restricted to levels below -// #r (01 1/ # , if no improvment)

    protein & hi#h protein diet (-2/ -3/ #r)

    ! available blood #lucose, protein decrease to 1/ 4

    5at & when blood level of carbohydrate and protein have been estabilshed,

    fat for the remainin# calories (in available need)

    Dietary plannin#

    6se food echan#e list

    Ade7uate amount of fruits and ve#etables

    Mil$ ! limited

    +upplement %a

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    Adrenocortical insuicienc!

    (Addison8s disease)

    Adrenal corte ! Atrophy (un$nown ori#in)

    ! impairment the function

    +ome causes & tubercolosis

    adrenal ectomy

    hypophysectomy

    ! absence of adrenocortical hormones

    9lucocorticoids

    %ortisol re#ulates the metabolism of carbohydrate, protein and fat.

    'n absence & rapid #lyco#en depletion, followed by hypo#lecemia (in a few

    hours

    After meals)

    Mineralocorticoids

    Aldosterone & maintainin# electrolite homeostatis (espec a : ;)

    a retention

    ; ecretion

    The production is not under the influence pituitary

    Deficiency aldosterone &

    'ncrease Naecretion

    'ncrease " retention

    ead to & lar#e salt loss < water

    Dehydration

    "ypotension e.t.c

    Andro#enic hormones

    =

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    +timulate protein synthesis in absence &

    >ei#ht loss

    Tissue wastin#

    ?eduction of muscle stren#th

    5ati7ue

    Dietary modification

    mild insuff &

    "i#her salt inta$e

    5re7uent meals

    (1 @ times a day)

    +evere insuff &

    Minerals metabolism in s controlled by #ivin# D*%A

    (dioycarticosterone acetate)

    "i#h protein and low carbohdydrate reduces the

    stimulation of insuline

    5re7uent intervals of meals

    Avoid simple carbohydrate candy, su#ar, e.t.c

    Thyroid "ormones

    ?e#ulates the oidation rate within the cells to influences

    hysical and mental #rowth

    5unctionin# of the nervous : muscles tissues

    %irculatory activity

    utrient metabolism

    'n the low level of blood thyro#lobulin

    3

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    Thyroid stimulatin# hormon (T+")

    (hypophsis anterior)

    +timulate

    Activity of thyroid #land increase

    ! with draw circulatory iodide

    ! concentrate

    ! oidizes ! iodine

    C

    Thyro#lobuline di iodotyrosine incorporate totyrosine

    %omple triiodotyronine to forms

    thyroine

    %irculatory

    B' protein bindin# iodine

    "yperthyroidism Eophtalmic #oiter

    Thyrotoicosis

    9rave disease

    Basedow8s diseases

    Disturbance of thyroid function due to the eessive secretion of thyroid #land with a

    conse7uent increase in the metabolic rate

    %hief symptomes &

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    wei#ht loss

    Eessive

    rominence of the eyes

    Enlar#ement of thyroid #land

    'ncrease appetide

    wea$ness

    cardic failure

    serum B' elevated

    basal metabolic increase 1/ 4 or more

    increase of nitro#en metabolism ! destruction of tissue protein

    ecretion of %a and increase ! osteoporosis, bone structure

    Dietary modification &

    restore normal nutrition

    3/// 1/// calories

    rotein -// -21 #r

    %a 2 = #rFday

    +upplement vit D, vit A, B comple, vit %

    "ypothroidism

    Decrease production of thyroid hormon

    ;nown as myedema (adult), cretinism (infant)

    #OINT DISEASE

    Arthritis

    @

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    ?heumatism

    9out

    ?heumaticfever &

    in child or youn# adult

    in adu7uate treatment

    permanent dema#e of heart

    osteoarthritis (de#enerative arthritis)

    especially women youn# adults

    inflamation, paintful

    cause (theory) &

    infection

    hypersensitivity

    hereditary

    metabolic disorders

    sympotmes & fati7ue

    pain

    stiffness

    deformity

    the disease is pro#ressive

    the symptomes may spontaneously dissapear but reappear

    later

    supportive diet

    in #ood nutritional status ! normal diet

    obese ! low calorie diet (wei#ht loss)

    0

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    in poor nutritional status ! hi#h calorie and protein diet (wei#ht #ain)

    in steroid therapy, when a retention

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    *idized

    6ric acid

    6ric acid is also synthesized in the body from simple carbon and nitro#en compound.

    +tores in liver and tissues

    Eerated in urine and via the bile into intestinal

    tract

    Dietary modification &

    owFrestriction purine diet

    urine content of blood (per -// #r)

    9roup ' & (/ -1 m#)

    ve#etables caviar

    fruits nuts

    mil$ butter

    chesse #elatin

    e##s su#ar

    bread and cereal fish roe

    9roup '' & (1/ -1/ m#)

    meats dry beans

    poultry peas

    fish spinach

    sea food oatmeal

    9roup ''' & (-1/ m# over)

    sweet breads $idney

    sardines meat etract

    liver brains

    I

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    purine restriction (#roup '', limited amount)

    ener#y obese low calorie diet (-2// -@// cal) in interval time

    protein restricted to about @/ #Fday

    fruits G = l per day

    coffe, tea ! allowed

    Osteo$orosis

    deficiency disease

    mostly the result of endocrine disorders

    hyperthyroidism

    hyperparathyroidism

    hyperadrenocortism

    acrome#aly

    immobilization

    rheumatoid arthritis

    sic$le cell anemia

    nutritional deficiency

    symptomes &

    low bac$ pain

    vertebral fracture

    Metabolic chan#es &

    characterized by a reduction in the total bone mass

    ne#ative balance of %a, , and level in blood

    Dietary treatment

    estro#en and andro#en

    (anabolic effect, mineral retention)

    -/

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    %a is recommended (-,1 # Fday)

    +upplement & %a

    Jit D

    rotein & (hi#h protein inta$e)

    --