Developing A Volume Sensor for Use in the Ventricular ......NSF-REU Summer 2004 LPPDLPPD A....
12
LPPD A. Linninger, BIOE Seminar, Oct 2003 - 1 Developing A Volume Sensor for Use in the Ventricular System of the Brain Seminar Presentation in the Department of Chemical Engineering, University of Illinois at Chicago, Chicago, IL, August 5, 2004. Joel Stanfield Professor Andreas Linninger NSF-REU Summer 2004
Transcript of Developing A Volume Sensor for Use in the Ventricular ......NSF-REU Summer 2004 LPPDLPPD A....
LPPDLPPDA. Linninger, BIOE Seminar, Oct 2003 - 1
Developing A Volume Sensor for Use in the Ventricular System of the Brain
Developing A Volume Sensor for Use in the Ventricular System of the Brain
Seminar Presentation in the Department of Chemical Engineering, University of Illinois at Chicago, Chicago, IL, August 5, 2004.
Joel StanfieldProfessor Andreas Linninger
NSF-REU Summer 2004
LPPDLPPDA. Linninger, BIOE Seminar, Oct 2003 - 2
OverviewOverview
• Background
• Box Volume Sensor
• Submersible Volume Sensor
• Communicating Vessels
• Future Research
LPPDLPPDA. Linninger, BIOE Seminar, Oct 2003 - 3
The Human BrainThe Human Brain
• Brain Parenchyma• Ventricular System-Ventricles, Choroid Plexus, Cerebrospinal Fluid (CSF)
LPPDLPPDA. Linninger, BIOE Seminar, Oct 2003 - 4
HydrocephalusHydrocephalus
Normal Hydrocephalus
LPPDLPPDA. Linninger, BIOE Seminar, Oct 2003 - 5
Volume Sensor Model Volume Sensor Model
AC
Volt Meter
VM
AC Power Supply
Inner Electrodes
Container (glass)
Tap Water
LPPDLPPDA. Linninger, BIOE Seminar, Oct 2003 - 6
Box Volume SensorBox Volume Sensor
Procedure- 100 mL of solution initially- 5 mL of solution added every
minute- Voltage Drop recorded at the
end of every minute- Final Measurement at 275 mL
LPPDLPPDA. Linninger, BIOE Seminar, Oct 2003 - 7
Box Volume Sensor ExperimentTap Water
1.901.95
2.002.05
2.102.15
95 115 135 155 175 195 215 235 255 275
Volume (mL)
Volta
ge D
rop (
volts
) Experiment 1Experiment 2Experiment 3Experiment 4Experiment 5
LPPDLPPDA. Linninger, BIOE Seminar, Oct 2003 - 8
Submersible Volume SensorSubmersible Volume Sensor
LPPDLPPDA. Linninger, BIOE Seminar, Oct 2003 - 9
0.901.001.101.201.301.401.501.601.70
90 140 190 240 290
Volume(mL)
Volta
ge D
rop(v
olts) Trial 1
Trial 2Trial 3Trial 4Trial 5
Submersible SensorTap Water
LPPDLPPDA. Linninger, BIOE Seminar, Oct 2003 - 10
Communicating VesselsCommunicating Vessels
LPPDLPPDA. Linninger, BIOE Seminar, Oct 2003 - 11
Communicating Vessels
11.051.1
1.151.2
1.251.3
1.351.4
95 145 195 245
Volume(mL)
Volta
ge D
rop(
volts
) Comm. 1Comm. 2Comm. 3Single 1Single 2Single 3
LPPDLPPDA. Linninger, BIOE Seminar, Oct 2003 - 12
Future ResearchFuture Research
• Design of a Better Submersible Sensor
• Physics of the Sensor
• Test Accuracy
