Department of Physiology & Cell Biology Ben-Gurion University of the Negev, Israel

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Department of Physiology & Cell Biology Ben-Gurion University of the Negev, Israel Cardiac Arrhythmia Research Laboratory Basic Cardiac Research in FOHS, BGU Yoram Etzion, MD, PhD

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Basic Cardiac Research in FOHS, BGU. Yoram Etzion, MD, PhD. Cardiac Arrhythmia Research Laboratory. Department of Physiology & Cell Biology Ben-Gurion University of the Negev, Israel. Stimulation Protocol. Various methods to model cardiac pathology and to evaluate structure & function. - PowerPoint PPT Presentation

Transcript of Department of Physiology & Cell Biology Ben-Gurion University of the Negev, Israel

Page 1: Department of Physiology & Cell Biology Ben-Gurion University of the Negev, Israel

Department of Physiology & Cell BiologyBen-Gurion University of the Negev, Israel

Cardiac Arrhythmia Research Laboratory

Basic Cardiac Research in FOHS, BGU

Yoram Etzion, MD, PhD

Page 2: Department of Physiology & Cell Biology Ben-Gurion University of the Negev, Israel

Various methods to model cardiac pathology and to evaluate structure & function

WT akt2-/-

LV

RV

LV

RV

Infarcted LV

RV

Sinus rhythm

S4S3

1mV

500 ms

S2

Sustained VT

Stimulation Protocol

Page 3: Department of Physiology & Cell Biology Ben-Gurion University of the Negev, Israel

Human Cardiac geneticsRuti Parvari & Yoram Etzion

Identified Gene of Interest

Manipulation of the Gene of interest in the rodent heart

Evaluation of the function of theGene of interest in rodent heart


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