Delivering clinical research to make patients, and the NHS, better Gynaecology SSG Sept 2015...
-
Upload
esmond-andrews -
Category
Documents
-
view
215 -
download
0
Transcript of Delivering clinical research to make patients, and the NHS, better Gynaecology SSG Sept 2015...
Delivering clinical research to make patients, and the NHS, better
Gynaecology SSG Sept 2015
Research
Jenny Forrest, Sub Specialty LeadWendy Cook, Research Delivery Manager
dd/mm/yyyy
Gynaecological Tumour Group National Perspective
Data from Portfolio ODP – Cut off 21/08/15
Gynaecological Tumour Group National Perspective
Data from Portfolio ODP – Cut off 21/08/15
Network
2014/2015 2015/2016
Commercial Non-Commercial Total Rank Commercial Non-
Commercial Total Rank
East Midlands 12 65 77 9 1 9 10 13
Eastern 35 312 347 1 3 125 128 1
Greater Manchester 17 105 122 4 3 27 30 4
Kent, Surrey and Sussex 18 39 57 12 0 12 12 11
North East and North Cumbria 12 55 67 11 0 17 17 8
North Thames 22 104 126 3 1 20 21 5
North West Coast 10 64 74 10 1 10 11 12
North West London 12 107 119 5 3 31 34 2
South London 50 142 192 2 3 31 34 2
South West Peninsula 12 94 106 6 2 17 19 7
Thames Valley and South Midlands 0 19 19 15 0 4 4 15
Wessex 15 8 23 14 5 0 5 14
West Midlands 24 59 83 8 4 11 15 10
West of England 4 51 55 13 1 15 16 9
Yorkshire and Humber 24 79 103 7 2 18 20 6
Gynaecological Tumour Group Open StudiesSouth West Peninsula
Data from Portfolio ODP – Cut off 21/08/15
Study Name UKCRN ID Study Type Study
DesignOpen to New
Sites?Total
Recruitment
DNA Methylation Study 1449 Non-Commercial
Observational Yes (LC) 211
ICON8 Trials Programme 9812 Non-Commercial
Interventional Yes 80
INTERLACE 11775 Non-Commercial
Interventional Yes 8
Gynaecological Tumour Group South West Peninsula Sites
Data from Portfolio ODP – Cut off 21/08/15
Trust
2014/2015 2015/2016
Commercial Non-Commercial Total Commercial Non-
Commercial Total
Northern Devon Healthcare NHS Trust 0 5 5 0 0 0
Plymouth Hospitals NHS Trust 0 42 42 0 1 1
Royal Cornwall Hospitals NHS Trust 3 8 11 0 0 0
Royal Devon and Exeter NHS Foundation Trust 2 9 11 0 0 0
South Devon Healthcare NHS Foundation Trust 5 4 9 2 0 2
Taunton and Somerset NHS Foundation Trust 0 23 23 0 16 16
Yeovil District Hospital NHS Foundation Trust 2 3 5 0 0 0
Data from CRN SWP Activity Data from EDGE July 2015
Acronym UKCRN ID Study Type Trust Investigator Name End Date Target Recruitment 2015/2016
Recruitment RTT
CX.5 (SHAPE):Early Stage 1A2 and 1B1
17481 Non-Commercial
Royal Cornwall Hospitals NHS Trust
Galaal, Ms Khadra 13-Jul-22 28 0 0 -1
DESKTOP III 11498 Non-Commercial
Royal Cornwall Hospitals NHS Trust
Galaal, Ms Khadra 31-Aug-18 2 0 0 -42
DNA Methylation Study
1449 Non-Commercial
Plymouth Hospitals NHS Trust
Hughes, Mr Geoff 31-Dec-17 20 104 1 439
DNA Methylation Study
1449 Non-Commercial
Royal Cornwall Hospitals NHS Trust
Lopes, Mr Alberto 31-Dec-17 30 23 0 -5
DNA Methylation Study
1449 Non-Commercial
Taunton and Somerset NHS Foundation Trust
Milliken, Mr David 01-Oct-15 15 66 16 342
GROINSS-V II 4971 Non-Commercial
Royal Cornwall Hospitals NHS Trust
Lopes, Mr Alberto 31-Jan-17 5 0 0 -79
ICON8: Weekly Chemotherapy in Ovarian Cancer
9812 Non-Commercial
Northern Devon Healthcare NHS Trust
Scatchard, Dr Kate 30-Nov-14 25 17 0 -54
ICON8: Weekly Chemotherapy in Ovarian Cancer
9812 Non-Commercial
Royal Cornwall Hospitals NHS Trust
Bailey, Dr Nigel 30-Nov-14 8 11 0 120
ICON8: Weekly Chemotherapy in Ovarian Cancer
9812 Non-Commercial
Royal Devon and Exeter NHS Foundation Trust
Scatchard, Dr Kate 30-Nov-14 12 27 0 54
7
Gynaecological Tumour Group South West Peninsula Open Studies
Acronym UKCRN ID Study Type Trust Investigator Name End Date Target Recruitment 2015/2016
Recruitment RTT
INTERLACE 11775 Non-Commercial
Northern Devon Healthcare NHS Trust
Forrest , Dr Jennifer 01-Jun-16 3 4 0 58
INTERLACE 11775 Non-Commercial
Royal Devon and Exeter NHS Foundation Trust
Forrest, Dr Jenny 01-Jun-16 9 4 0 -27
NiCCC Trial (BIBF1120) 15374 Non-
Commercial
Taunton and Somerset NHS Foundation Trust
Barlow, Dr Clare 15-Nov-19 4 0 0 -5
PETROC/OV21 7472 Non-Commercial
Plymouth Hospitals NHS Trust
Yiannakis, Dr DeINTERLACE 01-Jun-18 5 3 0 1
nnis
TRIOC 12591 Non-Commercial
Plymouth Hospitals NHS Trust
Yiannakis, Dr Dennis 01-Oct-14 5 0 0 -207
Gynaecological Tumour Group South West Peninsula Sites
Data from Portfolio ODP – Cut off 21/08/15
Gynaecological Tumour Group Open Studies
Data from Portfolio ODP – Cut off 21/08/15
East Midlands
Study Name Total Recruitment
DNA Methylation Study 34
ENGOT-EN2-DGCG-EORTC-55102 4
GROINSS-V II 41
ICON8 Trials Programme 67
INTERLACE 14
NCRN - 2597 AEZS-108 vs doxorubicin in 2nd line advanced endometrial ca
5
NCRN - 3244 - Masitinib + Gemcitabine VS Gemcitabine in Ovarian Cancer
1
PARAGON 3
TRIOC: TroVax® in Relapsed Ovarian Cancer 1
Eastern
Study Name Total Recruitment
BriTROC1 - Sample collection study in recurrent HGSOC 28
CORAL: Cancer of the OvaRy Abiraterone triaL 8
CTCR-OV04 221
CTCR-OV05 13
Diffusion weighted Imaging Study in Cancer of the Ovary (DISCOVAR) 47
DNA Methylation Study 77
GROINSS-V II 48
ICON8 Trials Programme 122
INTERLACE 1
METRO-BIBF 8
NCRN - 2746 / ARIEL 3 - Rucaparib in platinum-sensitive high-grade gynaecological cancer
1
PARAGON 8
PAZOFOS 3
Uterine LMS study 1
Gynaecological Tumour Group Open Studies
Data from Portfolio ODP – Cut off 21/08/15
Greater Manchester
Study Name Total Recruitment
BriTROC1 - Sample collection study in recurrent HGSOC 11
DNA Methylation Study 1
GROINSS-V II 26
ICON8 Trials Programme 107
INTERLACE 3
Metformin for endometrial cancer RCT 17
METRO-BIBF 7
MIRENA study 22
NCRN - 2746 / ARIEL 3 - Rucaparib in platinum-sensitive high-grade gynaecological cancer
4
NCRN - 3244 - Masitinib + Gemcitabine VS Gemcitabine in Ovarian Cancer
1
PARAGON 8
PAZOFOS 3
TRIOC: TroVax® in Relapsed Ovarian Cancer 2
Kent, Surrey and SussexStudy Name Total Recruitment
DNA Methylation Study 33
ENGOT-EN2-DGCG-EORTC-55102 1
EORTC Quality of Life Module for patients with vulva cancer
8
GROINSS-V II 12
ICON8 Trials Programme 79
METRO-BIBF 4
PARAGON 8
TRIOC: TroVax® in Relapsed Ovarian Cancer 5
Gynaecological Tumour Group Open Studies
Data from Portfolio ODP – Cut off 21/08/15
North East and North Cumbria
Study Name Total Recruitment
BriTROC1 - Sample collection study in recurrent HGSOC
1
Diffusion weighted Imaging Study in Cancer of the Ovary (DISCOVAR)
3
DNA Methylation Study 186
GROINSS-V II 7
ICON8 Trials Programme 72
INTERLACE 2
PARAGON 12
North Thames
Study Name Total Recruitment
BriTROC1 - Sample collection study in recurrent HGSOC 24
DEPICT 12
DNA Methylation Study 68
GROINSS-V II 30
ICON8 Trials Programme 130
INTERLACE 22
METRO-BIBF 11
NCRN - 2746 / ARIEL 3 - Rucaparib in platinum-sensitive high-grade gynaecological cancer
4
Uterine LMS study 1
Gynaecological Tumour Group Open Studies
Data from Portfolio ODP – Cut off 21/08/15
North West Coast
Study Name Total Recruitment
ICON8 Trials Programme 106
INTERLACE 2
MAPPING 25
METRO-BIBF 5
NCRN - 2597 AEZS-108 vs doxorubicin in 2nd line advanced endometrial ca
1
PARAGON 9
TRIOC: TroVax® in Relapsed Ovarian Cancer 6
North West London
Study Name Total Recruitment
BriTROC1 - Sample collection study in recurrent HGSOC 22
CANC - 3792 REFMAL 339: ME-344 with Topotecan in Solid Tumors 2
DEPICT 5
Diffusion weighted Imaging Study in Cancer of the Ovary (DISCOVAR) 17
ICON8 Trials Programme 70
MAPPING 39
NCRN - 2597 AEZS-108 vs doxorubicin in 2nd line advanced endometrial ca
8
NCRN - 2746 / ARIEL 3 - Rucaparib in platinum-sensitive high-grade gynaecological cancer
2
ProGem2 - Acelarin(NUC1031) plus Carboplatin for recurrent ovarian cancer
14
The role of obesity and diabetes in endometrial cancer 31
BriTROC1 - Sample collection study in recurrent HGSOC 22
Gynaecological Tumour Group Open Studies
Data from Portfolio ODP – Cut off 21/08/15
South LondonStudy Name Total Recruitment
ADC as a Prognostic Biomarker in Cervical Cancer 95
BriTROC1 - Sample collection study in recurrent HGSOC 2
CORAL: Cancer of the OvaRy Abiraterone triaL 14
DEPICT 3
Diffusion weighted Imaging Study in Cancer of the Ovary (DISCOVAR) 47
ICON8 Trials Programme 72
MAPPING 13
METRO-BIBF 15
NCRN - 2597 AEZS-108 vs doxorubicin in 2nd line advanced endometrial ca
8
NCRN - 2746 / ARIEL 3 - Rucaparib in platinum-sensitive high-grade gynaecological cancer
5
PARAGON 17
PAZOFOS 4
Uterine LMS study 1
Thames Valley and South Midlands
Study Name Total Recruitment
ICON8 Trials Programme 35
METRO-BIBF 4
PARAGON 2
TRIOC: TroVax® in Relapsed Ovarian Cancer
3
Gynaecological Tumour Group Open Studies
Data from Portfolio ODP – Cut off 21/08/15
Wessex
Study Name Total Recruitment
DNA Methylation Study 66
ICON8 Trials Programme 23
NCRN - 3244 - Masitinib + Gemcitabine VS Gemcitabine in Ovarian Cancer
3
West Midlands
Study Name Total Recruitment
BriTROC1 - Sample collection study in recurrent HGSOC 3
DNA Methylation Study 1
EPIVIN trial 14
GROINSS-V II 25
ICON8 Trials Programme 155
INTERLACE 4
MAPPING 5
NCRN - 2597 AEZS-108 vs doxorubicin in 2nd line advanced endometrial ca
5
NCRN - 3244 - Masitinib + Gemcitabine VS Gemcitabine in Ovarian Cancer
2
PARAGON 2
ROCkeTS 4
Gynaecological Tumour Group Open Studies
Data from Portfolio ODP – Cut off 21/08/15
West of England
Study Name Total Recruitment
BriTROC1 - Sample collection study in recurrent HGSOC 4
CORAL: Cancer of the OvaRy Abiraterone triaL 8
DNA Methylation Study 77
GROINSS-V II 1
ICON8 Trials Programme 80
METRO-BIBF 5
PARAGON 1
TRIOC: TroVax® in Relapsed Ovarian Cancer 3
Yorkshire and Humber
Study Name Total Recruitment
Actinomycin-D vs Methotrexate for treatment of low risk GTN 4
BriTROC1 - Sample collection study in recurrent HGSOC 11
DNA Methylation Study 111
ENGOT-EN2-DGCG-EORTC-55102 3
GROINSS-V II 27
ICON8 Trials Programme 68
INTERLACE 9
METRO-BIBF 2
NCRN - 2597 AEZS-108 vs doxorubicin in 2nd line advanced endometrial ca 2
NCRN - 2746 / ARIEL 3 - Rucaparib in platinum-sensitive high-grade gynaecological cancer
3
PARAGON 5
SHAPE - Simple Hysterectomy And Pelvic node dissection in Early cervix cancer
1
Division 1- Cancer - Contacts
• Duncan Wheatley, Clinical Specialty Lead [email protected] 01872 258312
• Jenny Forrest, Sub specialty lead [email protected] 01392 402106
• Wendy Cook, Research delivery manager
[email protected] 01392 406995
• Ann Courtman, Administrator [email protected]
01392 406966
16