David J. Hass, MD Assistant Clinical Professor of Medicine Yale University School of Medicine...

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Capsule Endoscopy: Clinical Case Vignettes David J. Hass, MD Assistant Clinical Professor of Medicine Yale University School of Medicine Gastroenterology Center of Connecticut, P.C.

Transcript of David J. Hass, MD Assistant Clinical Professor of Medicine Yale University School of Medicine...

Page 1: David J. Hass, MD Assistant Clinical Professor of Medicine Yale University School of Medicine Gastroenterology Center of Connecticut, P.C.

Capsule Endoscopy:Clinical Case Vignettes

David J. Hass, MDAssistant Clinical Professor of Medicine

Yale University School of MedicineGastroenterology Center of Connecticut, P.C.

Page 2: David J. Hass, MD Assistant Clinical Professor of Medicine Yale University School of Medicine Gastroenterology Center of Connecticut, P.C.

Case # 4

72 year-old male

Profuse diarrhea and night sweats

25 pound weight loss over six months

Page 3: David J. Hass, MD Assistant Clinical Professor of Medicine Yale University School of Medicine Gastroenterology Center of Connecticut, P.C.

Case # 4

Slightly cachectic

Physical exam otherwise unremarkable

Page 4: David J. Hass, MD Assistant Clinical Professor of Medicine Yale University School of Medicine Gastroenterology Center of Connecticut, P.C.

Case # 4

WBC 18,000 with a slight lymphocytic predominanceNormal chemistriesESR 120

Negative celiac serologiesNormal IgA level, normal chromogranin A levelNegative stool studies

Page 5: David J. Hass, MD Assistant Clinical Professor of Medicine Yale University School of Medicine Gastroenterology Center of Connecticut, P.C.

Case # 4

Negative EGDNegative ColonoscopyCT scan – borderline enlarged lymphadenopathyNormal gallium scanNormal small bowel series

A capsule endoscopy was performed….

Page 6: David J. Hass, MD Assistant Clinical Professor of Medicine Yale University School of Medicine Gastroenterology Center of Connecticut, P.C.

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Page 7: David J. Hass, MD Assistant Clinical Professor of Medicine Yale University School of Medicine Gastroenterology Center of Connecticut, P.C.
Page 8: David J. Hass, MD Assistant Clinical Professor of Medicine Yale University School of Medicine Gastroenterology Center of Connecticut, P.C.
Page 9: David J. Hass, MD Assistant Clinical Professor of Medicine Yale University School of Medicine Gastroenterology Center of Connecticut, P.C.

Case # 4

Double balloon enteroscopy performed for tissue sampling

Diagnosis: Small bowel diffuse large B-cell lymphoma

Patient underwent CHOP chemotherapy with a good clinical response, dying of an unrelated cause 3 yrs after his diagnosis of lymphoma.

Page 10: David J. Hass, MD Assistant Clinical Professor of Medicine Yale University School of Medicine Gastroenterology Center of Connecticut, P.C.

Case # 4Diffuse large B cell lymphoma of the small bowel is an

uncommon neoplasm. In contrast to gastric lymphoma, small bowel B cell lymphomas do not appear to be associated with H pylori.

Capsule endoscopy has proven useful for diagnosis of obscure causes of gastrointestinal illness. In this case, making the diagnosis of a mass lesion that was not found using other methods.