Dabigatran
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Dabigatran Rivaroxaban- 13 C 6 Edoxaban Dabigatran- 13 C 6 Apixaban Rivaroxaban Time (min) Relative Abundance (%) 0. 0 1.0 2.0 3.0 0.0 1.0 2.0 3.0 Supplemental Digital Content 3. Typical post-column infusion ion suppression experimental data, collected whilst a solution of all analytes and internal standards (each 10 mg/L) was infused post-column via a syringe (10 µL/min). Shown are representative extracted ion chromatograms (± 5 ppm window) of a precipitated blank serum sample (grey trace) and a solvent blank (black trace). Overlaid are chromatograms to illustrate the retention times of the analytes.
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Transcript of Dabigatran
Dabigatran
Rivaroxaban-13C6
Edoxaban
Dabigatran-13C6
Apixaban
Rivaroxaban
Time (min)
Rel
ativ
e A
bund
ance
(%
)
0.0 1.0 2.0 3.0 0.0 1.0 2.0 3.0
Supplemental Digital Content 3. Typical post-column infusion ion suppression experimental data, collected whilst a solution of all analytes and internal standards (each 10 mg/L) was infused post-column via a syringe (10 µL/min). Shown are representative extracted ion chromatograms (± 5 ppm window) of a precipitated blank serum sample (grey trace) and a solvent blank (black trace). Overlaid are chromatograms to illustrate the retention times of the analytes.
