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D I S C U S S I O NC E N T E R

ESIC PHARMACISTESIC PHARMACISTOnlineTestSeries

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TOTAL 23 TEST WILL BE CONDUCTED

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ThetestseriesisdesignedforthepreparationofESICPHARMACISTEXAMandpromisestodeliveritsFinestintheexams.

TopicTest(Specifiedsyllabus)18

Aptitude,GeneralAwareness,GeneralIntelligence03

MockTest(FullLengthTest)02

TestwillbeconductedtillPHARMACISTEXAM

1

Multiple Choice Based Questions (MCQ) & Same as ESICF Pattern of the Test Series :

Pharmacistexamination.

F TimingsforTestSeries:

ForGK,GSandTopicwisetest:2Hr./100Questions

ForMockTest:3Hr./125Questions

oftheTestSerieswillbeEnglish.Medium

AccordingtoinstructionF Day&TimingsofExam:

Rankandalldetailliketotalnumberofstudentappear,IndividualF Announcementofresults:

Score, Highest score done by a student by this Every candidate judge their individual

performanceduringonlinetest.

Youcanseethe afterthecompletionoftest.F Answerkey

F JOINUS

ü Makeaonlinepaymenton andstartthetestinstantlyasperwww.gdconlinetest.in

theschedule.Ucanalsofollowthesame.

GENERAL INSTRUCTIONS FOR THE TEST SERIES GENERAL INSTRUCTIONS FOR THE TEST SERIES



2

Students can have difficulty and topicwise analysis after finishing the exam.Itgivesclearpictureaboutthestrongandweaktopicsandstudentcancomparetheirresultwithtoppers.

1. LevelwiseIndividualAverageScore

PERFORMANCE ANALYSIS OF STUDENT WITH TOPPER'S



3

2.Performaceanalysisofstudent

3.AccuracyAnalysis

4.TestCompletionTimeanalysis



Test TestType NO.ofQuestion,Marks&Time

TestNo.-1

TEST SERIES SYLLABUS

Syllabus

Pharmaceutics-I

GpatDiscussionCentreESICAllIndiaTestSeries

1.

4

TestNo.-2 Pharmaceutics-II

TestNo.-16 HealthEducationandCommunityPharmacy 100-Que.,300-mark120-min

100-Que.,300-mark120-min


2.

16.

TestNo.-3 PharmaceuticalChemistry-I3.

TestNo.-4 PharmaceuticalChemistry-II



4.

TestNo.-5 PharmacologyandToxicology5.

TestNo.-6 PharmacologyandToxicology



6.

TestNo.-7 PharmacologyandToxicology7.

TestNo.-8 Pharmacognosy



8.

TestNo.-9 Pharmacognosy 100-Que.,300-mark120-min

9.

TestNo.-10 Pharmaceuticaljurisprudence10.

TestNo.-11 Pharmaceuticaljurisprudence



11.

TestNo.-12 HumanAnatomyandPhysiology12.

TestNo.-13 HumanAnatomyandPhysiology



13.

TestNo.-14 BiochemistryandClinicalPathology 100-Que.,300-mark120-min

14.

TestNo.-15 BiochemistryandClinicalPathology 100-Que.,300-mark120-min

15.



5

TestNo.-17 HospitalandClinicalPharmacy17. 100-Que.,300-mark120-min

TestNo.-18 DrugStoreandBusinessManagement18. 100-Que.,300-mark120-min

TestNo.-19 ReasoningAptitude,GK,GS19. 100-Que.,300-mark120-min



TestNo.-22 FullLengthTest22. 125-Que.,375-mark 120-min

TestNo.-23 FullLengthTest23. 125-Que.,375-mark 120-min

S.No.

1.

2.

3.

4.

ExamType

Multiple

Choice

Questions

Subjects

Technical

Knowledge

Aptitude

General

Awareness

General

Intelligence

Questions Marks ExamDuration

2Hours

100

25

100

25

Total 125 125

EXAM PATTERN OF FINAL ESIC PHARMACIST EXAM

• Coding-Decoding. • Directions. • BloodRelations. • AlphabetSeries.

• Non-VerbalSeries. • DecisionMaking. • Statements&Conclusions. •NumberRanking.

• Clocks&Calendars. • DataInterpretation. • NumberSeries. • Syllogism.

• ArithmeticalReasoning. • EmbeddedFigures. • MirrorImages. • Analogy.

• Statements&Arguments. • CubesandDice.

Aptitude, General Intelligence



6

DETAIL SYLLABUS OF ESIC PHARMACIST

PHARMACEUTICS-I

1. Introductionofdifferentdosageforms:Theirclassificationwiththeirexamples-theirrelative

applications.Familiarizationwithnewdrugdeliverysystems.

2. IntroductiontoPharmacopoeiaswithspecialreferencetotheIndianPharmacopoeia.

3. Metrology:Systemsofweightsandmeasures.Calculationsincludingconversionfromonesystemto

anothersystem.Percentagecalculationsandadjustmentofproducts.Useofalligationmethodin

calculations.Isotonicsolutions.

4. Packagingofpharmaceuticals:Desirablefeaturesofacontainerandtypesofcontainers.Studyof

glass&plasticsasmaterialsforcontainersandrubberasamaterialforclosure-theirmeritsand

demerits.Introductiontoaerosolpackaging.

5. Sizereduction:Objectivesandfactorsaffectingsizereduction,methodsofsizereduction-studyof

Hammermill,ballmill,FluidenergymillandDisintegrator.

6. Sizeseparation:Sizeseparationbysifting.Officialstandardsforpowders.Sedimentationmethodsof

sizeseparation.ConstructionandworkingofCycloneseparator.

7. MixingandHomogenization:Liquidmixingandpowdermixing,mixingofsemisolids.Studyof

SilversonMixer-Homogenizer,planetaryMixer;Agitatedpowdermixer;TripleRollerMill;Propeller

Mixer,colloidMillandHandHomogeniser.Doubleconemixer.

8. ClarificationandFiltration:Theoryoffiltration,Filtermedia;Filteraidsandselectionoffilters.Study

ofthefollowingfiltrationequipments-FilterPress,sinteredfilters,Filtercandles,Metafilter.

9. ExtractionandGalenicals:

(a) Studyofpercolationandmacerationandtheirmodification,continuoushotextraction-

Applicationinthepreparationoftincturesandextracts.

(b) IntroductiontoAyurvedicdosageforms.

10. Heatprocess-Evaporation-Definition-Factorsaffectingevaporation-studyofevaporatingstilland

Evaporatingpan.

11. Distillation:SimpledistillationandFractionaldistillation,steamdistillationandvacuumdistillation.

Studyofvacuumstill,preparationofpurifiedwaterI.P.Constructionandworkingofthestillused

forthesame.

12. Introductiontodryingprocess:StudyofTrayDryers;FluidizedBedDryer,VacuumDryerandFreeze

Dryer.

13.Sterilization-Conceptofsterilizationanditsdifferencesfromdisinfections-Thermalresistanceof

microorganisms.Detailedstudyofthefollowingsterilizationprocess.

1. Sterilizationwithmoistheat

2. Dryheatsterilization

3. Sterilizationbyradiation

4. Sterilizationbyfiltration

5. Gaseoussterilization.



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Aseptictechniques:Applicationsofsterilizationprocessinhospitalsparticularlywithreferenceto

surgicaldressingsandintravenousfluids.Precautionsforsafeandeffectivehandlingofsterilization

equipment.

14. ProcessingofTablets:Definition;differenttypeofcompressedtablesandtheirproperties.Processes

involved in the production of tablets; Tablets excipients; Defects in tablets; Evaluation of Tablets;

Physical standards including Disintegration and Dissolution. Tablet coating-sugar coating; films

coating, enteric coating and micro-encapsulation (Tablet coating may be dealt in elementary

manner)

15. ProcessingofCapsules:Hardandsoftgelatincapsules;differentsizesofcapsules;fillingofcapsules;

handlingandstorageofcapsules.Specialapplicationsofcapsules.[

16. Studyofimmunologicalproductslikesera,vaccines,toxoids&theirpreparations.

PHARMACEUTICALCHEMISTRY-I

1. Generaldiscussiononthefollowinginorganiccompoundsincludingimportantphysicalandchemicalproperties,medicinalandpharmaceuticalusesstorageconditionsandchemicalincompatibility.

(A) Acids,basesandbuffers:Boricacid,Hydrochloricacid,StrongAmmoniumhydroxide,

Calciumhydroxide,Sodiumhydroxideandofficialbuffers.

(B) Antioxidants:Hypophosphorousacid,Sulphurdioxide,Sodiumbisulphate,Sodiummeta

bisulphite,Sodiumthiosulphate,NitrogenandSodiumnitrite.

(C) Gastrointestinalagents:

1. Acidifyingagents-DiluteHydrochloricacid.

2. Antacids-Sodiumbicarbonate,Aluminumhydroxidegel,Aluminumphosphate,

Calciumcarbonate,Magnesiumcarbonate,Magnesiumtrisilicate,Magnesium

oxide,Combinationsofantacidpreparations.

3. ProtectiveandAdsorbents-BismuthsubcarbonateandKaolin.

4. Salinecathartics-SodiumpotassiumtartrateandMagnesiumsulphate.

(D) TopicalAgents:

1. Protective-Talc,ZincOxide,Calamine,Zincstearate,Titaniumdioxide,siliconepolymers.

2. Antimicrobials andAstringents:Hydrogenperoxide*, Potassiumpermanganate,

Chlorinatedlime,Iodine,SolutionsofIodine,Povidone-iodine,Boricacid,Borax,

Silvernitrate,Mild silverprotein,Mercury, yellowMercuricoxide,Ammoniated

mercury.

3. Sulphuranditscompounds-Sublimedsulphur,Percipitatedsulphur,Selenium

sulphide.

4. Astringents-AlumandZincSulphate.

(E) DentalProducts:Sodiumfluoride,Stannousflouride,Calciumfluoride,Calciumcarbonate,

Sodiummetaphosphate,Di-calciumphosphate,Strontiumchloride,Zincchloride.

(F) Inhalants-Oxygen,Carbondioxide,Nitrousoxide.

(G) Respiratorystimulants:Ammoniumcarbonate.

(H) ExpectorantsandEmetics:Ammoniumchloride*,Potassiumiodide,Antimonypotassium

tartrate.

(I) Antidotes:Sodiumnitrite.



2. MajorIntraandExtracellularelectrolytes:

(A) Electrolytesusedforreplacementtherapy-Sodiumchlorideanditspreparations,

Potassiumchlorideanditspreparations.

(B) Physiologicalacid-basebalanceandelectrolytesused-Sodiumacetate,PotassiumAcetate,

SodiumbicarbonateInj.,Sodiumcitrate,Potassiumcitrate,Sodiumlactateinjection,

Ammoniumchlorideanditsinjection.

(C) Combinationoforalelectrolytepowdersandsolutions.

3. InorganicofficialcompoundsofIron,IodineandCalcium,FerrousSulphateandCalciumGluconate.

4. Radiopharmaceuticalsandcontrastmedia:Radioactivity-Alpha;BetaandGammaRadiations,

Biologicaleffectsofradiations,Measurementofradioactivity,G.M.Counter,Radioisotopes-their

uses,Storageandprecautionswithspecialreferencetotheofficialpreparations.Radioopaque

contrastmedia-Bariumsulfate.

5. QualitycontrolofDrugsandpharmaceuticals:Importanceofqualitycontrol,significanterrors,

methodsusedforqualitycontrol,sourcesofimpuritiesinpharmaceuticals.LimittestsforArsenic,

Chloride,Sulfate,IronandHeavymetals.

6. IdentificationtestsforcationsandanionsasperIndianPharmacopoeia.

PHARMACOGNOSY

1. Definition,historyandscopeofPharmacogonosyincludingindigenoussystemofmedicine.

2. Varioussystemsofclassificationofdrugsofnaturalorigin.

3. Adulterationanddrugevaluation;significanceofPharmacopoeialstandards.

4. Briefoutlineofoccurrence,distribution,outlineofisolation,identificationtests,

therapeuticeffects

andpharmaceuticalapplicationofalkaloids,terpenoids,glycosides,volatileoils,tanninsandresins.

5. Occurrence,distribution,organolepticevaluation,chemicalconstituentsincludingtestswherever

applicableandtherapeuticefficacyoffollowingcategoriesofdrugs.

(a) Laxatives:Aloes,Rhubarb,Castoroil,Ispaghula,Senna.

(b) Cardiotonics-Digitalis,Arjuna.

(c) Carminatives&G.I.regulators:Umbelliferousfruits,Coriander,Fennel,Ajowan,

Cardamom,Ginger,Blackpepper,Asafoetida,Nutmeg,Cinnamon,Clove.

(d) Astringents-Catechu.

(e) Drugsactingonnervoussystem:Hyoscyamus,Belladonna,Aconite,Ashwagandha,

Ephedra,Opium,Cannabis,Nux-vomica.

(f) Antihypertensive-Rauwolfia.

(g) Antitussives-Vasaka,Tolubalsam,Tulsi.

(h) Antirheumatics-Guggal,Colchicum.

(i)Antitumour-Vinca.

(j)Antileprotics-Chaulmoograoil.

(k) Antidiabetics-Pterocarpus,Gymnemasylvestro.

(l)Diuretics-Gokhru,Punarnava.

(m) Antidysenterics-Ipecacuanha.8



9

(n) Antisepticsanddisinfectants-Benzoin,Myrrh,Neem,Curcuma.

(o) Antimalarials-Cinchona.

(p) Oxytocics-Ergot.

(q) Vitamins-SharkliveroilandAmla.

(r) Enzymes-Papaya,Diastase,Yeast.

(s) Perfumesandflavoringagents-peppermintoil,Lemonoil,Orangeoil,lemongrassoil,

sandalwood.

(t) Pharmaceuticalaids-Honey,Arachisoil,starch,kaolin,pectin,oliveoil.Lanolin,Beeswax,

Acacia,Tragacanth,sodiumAlginate,Agar,Guargum,Gelatin.

(u) Miscellaneous:Liquorice,Garlic,picrorhiza,Diascorea,Linseed,shatavari,shankhpushpi,

pyrethrum,Tobacco.

6. Collectionandpreparationofcrudedrugsforthemarketasexemplifiedbyergot,opium,rauwolfia,

digitalisandsenna.

7. Studyofsource,preparationandidentificationoffibersusedinsuturesandsurgicaldressings

cotton,silk,woolandregeneratedfibers.

8. GrossanatomicalstudiesofSenna,Datura,Cinnamon,Cinchona,Coriander,Fennel,Clove,Ginger,

Nux-vomica,Ipecacuanha.

BIOCHEMISTRYANDCLINICALPATHOLOGY

1. IntroductiontoBiochemistry.

2. Briefchemistryandroleofproteins,polypeptidesandaminoacids,classification,Qualitativetests,

Biologicalvalue,Deficiencydiseases.

3. Briefchemistryandroleofcarbohydrates,classification,qualitativetests,Diseasesrelatedto

carbohydratemetabolism.

4. Briefchemistryandroleoflipids,classificationandqualitativetests.Diseasesrelatedtolipids

metabolism.

5. Briefchemistryandroleofvitaminsandcoenzymes

6. Roleofmineralsandwaterinlifeprocesses.

7. Enzymes:Briefconceptofenzymaticactionfactorsaffectingit.Therapeuticandpharmaceutical

importance.

8. Briefconceptofnormalandabnormalmetabolismofproteins,carbohydrateandlipids.

9. Introductiontopathologyofbloodandurine

(a) Lymphocytesandplatelets,theirroleinhealthanddisease

(b) Erythrocytes-Abnormalcellsandtheirsignificance

(c) Abnormalconstituentsofurineandtheirsignificanceindiseases.



HUMANANATOMYANDPHYSIOLOGY

1. ScopeofAnatomyandphysiology:DefinitionofvarioustermsusedinAnatomy.

2. Structureofcell,functionofitscomponentswithspecialreferencetomitochondriaandmicrosomes.

3. ElementaryTissues:Elementarytissuesofthebody,i.e.epithelialtissue,musculartissue,connective

tissueandnervoustissue.

4. StructureandfunctionofSkelton.Classificationofjointsandtheirfunction.Jointdisorders.

5. Compositionofblood,functionsofbloodelements.Bloodgroupandcoagulationofblood.Brief

informationregardingdisordersofblood.

6. Nameandfunctionsoflymphglands.

7. Structureandfunctionsofvariouspartsoftheheart.Arterialandvenoussystemwithspecialreference

tothenamesandpositionsofmainarteriesandveins.Bloodpressureanditsrecording.Brief

informationaboutcardiovasculardisorders.

8. Variouspartsofrespiratorysystemandtheirfunctions,physiologyofrespiration.

9. Variouspartsofurinarysystemandtheirfunctions,structureandfunctionsofkidney.Physiologyof

urineformation.Patho-physiologyofrenaldiseasesandedema.

10.Structureofskeletalmuscle,physiologyofmusclecontraction.Names,positions,attachmentsand

functionsofvariousskeletalmuscles.Physiologyofneuromuscularjunction.

11.Variouspartsofcentralnervoussystem,brainanditsparts,functionsandreflexaction.Anatomy

andphysiologyofautonomicnervoussystem.

12.Elementaryknowledgeofstructureandfunctionsoftheorgansoftaste,smell,ear,eyeandskin.

Physiologyofpain.

13.Digestivesystem:-Namesofvariouspartsofdigestivesystemandtheirfunctions.structureand

functionsofliver,physiologyofdigestionandabsorption.

14.EndocrineglandsandHormones.Locationofglands,theirhormonesandfunctions.

15.ReproductiveSystem:PhysiologyandAnatomyofReproductivesystem.

HEALTHEDUCATIONANDCOMMUNITYPHARMACY

1. Conceptofhealth:Definitionofphysicalhealth,mentalhealth,socialhealth,spiritualhealth

determinantsofhealth,indicatorsofhealth,conceptofdisease,naturalhistoryofdiseases,thedisease

agents,conceptofpreventionofdiseases.

2. Nutritionandhealth:Classificationoffoods,requirements,diseasesinducedduetodeficiencyof

proteins,vitaminsandminerals-treatmentandprevention.

3. Demographyandfamilyplanning:Demographycycle,fertility,familyplanning,contraceptive

methods,behavioralmethods,hormonalcontraceptives,populationproblemofIndia.

4. Firstaid:Emergencytreatmentinshock,snake-bite,burns,poisoning,heartdisease,fracturesand

resuscitationmethods,Elementsofminorsurgeryanddressings.

5. Environmentandhealth:Sourceofwatersupply,waterpollution,purificationofwater,healthand

air,noise,light-solidwastedisposalandcontrol-medicalentomology,arthropodbornediseasesand

theircontrol,rodents,animalsanddiseases.

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6. Fundamentalprinciplesofmicrobiology:Classificationofmicrobes,isolation,stainingtechniques

oforganismsandprevention.

7. Communicablediseases:Causativeagents,modeoftransmissionandprevention.

(a) Respiratoryinfections-chickenpox,measles,influenza,diphtheria,whoopingcoughand

tuberculosis.

(b) Intestinalinfection:poliomyelitis,Hepatitis,cholera,Typhoid,foodpoisoning,Hookworm

infection.

(c) Arthropodborneinfections:plague,Malaria,filariases.

(d) Surfaceinfection:Rabies,Trachoma,Tetanus,Leprosy.

(e) Sexuallytransmitteddiseases:Syphilis,Gonorrhoea,AIDS.

8. Non-communicablediseases:Causativeagents,prevention,careandcontrol:Cancer,Diabetes,

Blindness,Cardiovasculardisease.

9. Epidemiology:Itsscope,methods,uses,dynamicsofdiseasetransmission.Immunityand

immunization:Immunologicalproductsandtheirdoseschedule.Principlesofdiseasecontroland

prevention,hospitalacquiredinfection,preventionandcontrol.Disinfection,typesofdisinfection

procedures,for-faces,urine,sputum,roomlinen,dead-bodies,instruments.

PHARMACEUTICS-II

1. DispensingPharmacy:

(I)Prescriptions:Readingandunderstandingofprescriptions;Latintermscommonlyused

(Detailedstudyisnotnecessary),Modernmethodsofprescribing,adoptionofmetricsystem.

Calculationsinvolvedindispensing.

(II) Incompatibilitiesinprescriptions:studyofvarioustypesofincompatibilities-physical,

chemicalandtherapeutic.

(III) Posology:Doseanddosageofdrugs,factorsinfluencingdose,calculationsofdosesonthe

basisofage,sex,surfaceareaandveterinarydoses.

2. DispensedMedications:(Note:Adetailedstudyofthefollowingdispensedmedicationisnecessary.

Methodsofpreparationwiththeoreticalandpracticalaspects,useofappropriatecontainersand

closures.Speciallabelingrequirementsandstorageconditionsshouldbehigh-lighted).

(I)Powders:Typeofpowders-Advantagesanddisadvantagesofpowders,Granules,cachets

andtablettriturates.Preparationofdifferenttypesofpowdersencounteredinprescriptions.

Weighingmethods,possibleerrorsinweighing,minimumweighableamountsandweighing

ofamaterialbelowtheminimumweighableamount,geometricdilutionandproperusage

andcareofdispensingbalance.

(II) LiquidoralDosageforms:

a. Monophasic-Theoreticalaspectsincludingcommonlyusedvehicles,essentialadjuvant

likestabilizers,colorantsandflavors,withexamples.

Reviewofthefollowingmonophasicliquidswithdetailsofformulationandpracticalmethods. b. BiphasicLiquidDosageForms:

i. Suspensions:(elementarystudy)Suspensionscontainingdiffusiblesolidsandliquids

andtheirpreparations.Studyoftheadjuvantusedlikethickeningagents,wettingagents, 11



theirnecessityandquantitytobeincorporated,suspensionsofprecipitateformingliquids

liketinctures,theirpreparationsandstability.suspensionsproducedbychemicalreaction.

Anintroductiontoflocculated/non-flocculatedsuspensionsystem.

ii.Emulsions: Types of emulsions, identification of emulsion system, formulation of

emulsions, selection of emulsifying agent. Instabilities in emulsions, preservation of

emulsions.

c. Semi-SolidDosageForms:

i. Ointments:Typesofointments,classificationandselectionofdermatologicalvehicles.

Preparationandstabilityofointmentsbythefollowingprocesses:

(a) Trituration

(b) Fusion

(c) Chemicalreaction

(d) Emulsification.

ii. Pastes:Differencesbetweenointmentsandpastes,Basesofpastes.Preparationofpastes

andtheirpreservation.

iii.Jellies:Anintroductiontothedifferenttypesofjelliesandtheirpreparation.

iv.Anelementarystudyofpoultice.

v. Suppositoriesandpassaries:Theirrelativemeritsanddemerits,typesofsuppositories,

suppositorybases,classification,properties.preparationandpackingofsuppositories.

Useofsuppositoriesofdrugabsorption.

3. Dentalandcosmeticpreparations:IntroductiontoDentifrices,facialcosmetics,Deodorants.Anti

perspirants,shampoo,HairdressingsandHairremovers.

4. SterileDosageforms:

a. Parenteraldosageforms-Definition,Generalrequirementsforparenteraldosageforms.Types

ofparenteralformulations,vehicles,adjuvant,processingandpersonnel,Facilitiesandquality

control.PreparationofIntravenousfluidsandadmixtures-Totalparenteralnutrition,

Dialysisfluids.

b. Sterilitytesting:particulatemattermonitoring-Facultysealpackaging.

c. Ophthalmicproducts:studyofessentialcharacteristicsofdifferentophthalmicpreparations.

Formulation:additives,specialprecautionsinhandlingandstorageofophthalmicproducts.

PHARMACEUTICALCHEMISTRY-II

1. Introductiontothenomenclatureoforganicchemicalsystemswithparticularreferenceto

hetero-cyclicsystemcontainingupto3rings.

2. Thechemistryoffollowingpharmaceuticalorganiccompoundscoveringtheirnomenclature,chemical

structure,usesandtheimportantphysicalandchemicalproperties(chemicalstructureofonlythose

compoundsmarkedwithasterisk(*).Thestabilityandstorageconditionsandthedifferenttypeof

pharmaceuticalformulationsofthesedrugsandtheirpopularbrandnames:

(1) AntisepticsandDisinfectants:Proflavine*,Benzalkoniumchloride,Cetrimide,Chlorocresol,

chloroxylenol,Formaldehydesolution,Hexachlophene,Liquefiedphenol,Nitrofurantoin.12



(2) Sulphonamides: Sulphathiazole , Succ inylsulphathiazole , Sulphadimethoxine ,

sulphamethoxypyrdazine,sulpjamethoxazole,Co-trimoxazole,sulfacetamide*

(3) AntileproticDrugs:Clofazimine,Thiambutosine,Dapsone*,solapsone.

(4) Anti-tubercularDrugs:Isoniazid*,PAS*,Streptomycin,Rifampicin,Ethambutol*,

Thiacetazone,Ethionamide,cycloserine,pyrazinamide*.

(5) AntimoebicandAnthelminticDrugs:Emetine,Metronidazole,Halogenated

hydroxyquinolines,Diloxanidefuroate,Paromomycin,Piperazine*,Mebendazole,D.E.C.*

(6) Antibiotics:Benzylpenicillin*,Phenoxymethylpenicillin*,Benzathinepenicillin,Ampicillin*,

Cloxacillin,Carbencicillin,Gentamicin,Neomycin,Erythromycin,Tetracycline,Cephalexin,

Cephaloridine,Cephalothin,Griseofulvin,Chloramphenicol.

(7) Antifungalagents:Udecylenicacid,Tolnaftate,Nystatin,Amphotericin,Hamycin.

(8) AntimalarialDrugs:Chloroquine*,Amodiaquine,Primaquine,Proguanil,Pyrimethamine*,

Quinine,Trimethoprim.

(9) Tranquilizers:Chlorpromazine*,Prochlorperazine,Trifluoperazine,Thiothixene,

Haloperiodol*,Triperiodol,Oxypertine,Chlordizepoxide,Diazepam*,Lorazepam,

Meprobamate.

(10)Hypnotics:Phenobarbitone*,Methyprylon,Paraldehyde,Triclofosodium.

(11)GeneralAnaesthetics:Halothane*,Cyclopropane*,Diethylether*,Methohexitalsodium,

Thiopentalsodium,Trichloroethylene

(12)AntidepressantDrugs:Amitriptyline,Nortryptyline,Imperamine*,Phepelzine,Tranylcypromine.

(13)Analeptics:Theophylline,Caffeine*,Coramine*,Dextro-amphetamine.

(14)Adrenergicdrugs:Adrenaline*,Noradrenaline,Isoprenaline*,Phenylephrine,Salbutamol,

Terbutaline,Ephedrine*,Pseudoephedrine.

(15)Adrenergicantagonist:Tolazoline,Propranolol*,Practolol.

(16)CholinergicDrugs:Neostigmine*,Pyridostigmine,Pralidoxime,Pilocarpine,Physostigmine*.

(17)CholinergicAntagonists:Atropine*,Hyoscine,Homatropine,Propantheline*,Benztropine,

Tropicamide,Biperiden*.

(18)DiureticDrugs:Furosemide*,Chlorothiazide,Hydrochlorothiazide*,Benzthiazide,Urea*,

Mannitol*,EthacrynicAcid.

(19)CardiovascularDrugs:Ethylnitrite*,Glyceryltrinitrate,Alphamethyldopa,Guanethidine,

Clofibrate,Quinidine.

(20)HypoglycemicAgents:Insulin,Chlorpropamide*,Tolbutamide,Glibenclamide,Phenformin*,

Metformin.

(21)CoagulantsandAnticoagulants:Heparin,Thrombin,Menadione*,Bisphydroxy-coumarin,

Warfarinsodium.[3h]

(22)LocalAnaesthetics:Lignocaine*,Procaine*,Benzocaine.

(23)HistamineandantiHistaminicAgents:Histamine,Diphenhydramine*,Promethazine,

Cyproheptadine,Mepyramine*,Pheniramine,Chlorpheniramine*.

(24)Non-steriodalanti-inflammatoryagents:Indomethacin*,Phenylbutazone*,

Oxyphenbutazone,Ibuprofen. 13



(25)ThyroxineandAntithyroids:Thyroxine*,Methimazole,Methylthiouracil,Propylthiouracil.

(26)DiagnosticAgents:LopanoicAcid,Propyliodone,Sulfobromopthalein-sodium,

Indigotindisulfonate,IndigoCarmine,Evansblue,CongoRed,Fluoresceinsodium.

(27)Anticonvulsants,cardiacglycosides,Antiarrhythmic,Antihypertensives&Vitamins.

(28)SteroidalDrugs:Betamethasone,Cortisone,Hydrocortisone,Prednisolone,Progesterone,

Testosterone,Oestradiol,Nandrolone.

(29)Anti-NeoplasticDrugs:Actinomycin,Azathioprine,Busulphan,Chloramubucil,Cisplatin,

Cyclophosphamide,DaunorubicinHydrochoride,Fluorouracil,Mercaptopurine,

Methotrexate,Mytomycin.

PHARMACOLOGY&TOXICOLOGY

1. Introductiontopharmacology,scopeofpharmacology.

2. Routesofadministrationofdrugs,theiradvantagesanddisadvantages.Variousprocessesof

absorptionofdrugsandthefactorsaffectingthem.Metabolism,distributionandexcretionofdrugs.

3. Generalmechanismofdrugsactionandtheirfactorswhichmodifydrugsaction.

4. Pharmacologicalclassificationofdrugs.Thediscussionofdrugsshouldemphasizethefollowing

aspects:

(i)DrugsactingonthecentralNervoussystem:

a. Generalanaesthetics-adjunctiontoanaesthesia,intravenousanaesthetics.

b. Analgesicantipyreticsandnon-steroidalanti-inflammatorydrugs-Narcoticanalgesics,

Antirheumaticandanti-goutremedies,SedativesandHypnotics,

psychopharmacologicalagents,anticonvulsants,analeptics.

c. Centrallyactingmusclerelaxantsandantiparkinsonismagents.

(ii) Localanesthetics.

(iii) Drugsactingonautonomicnervoussystem.

a. Cholinergicdrugs,Anticholinergicdrugs,anticholinesterasedrugs.

b. Adrenergicdrugsandadrenergicreceptorblockers.

c. Neuroneblockersandganglionblockers.

d. Neuromuscularblockers,usedinmyastheniagravis.

(iv) Drugsactingoneye:Mydriatics,drugsusedinglaucoma.

(v) Drugsactingonrespiratorysystem:Respiratorystimulants,Bronchodilators,Nasal

decongestants,ExpectorantsandAntitussiveagents.

(vi) Antacids:Physiologicalroleofhistamineandserotonin,HistamineandAntihistamines,

prostaglandins.

(vii)Cardiovasculardrugs:Cardiotonics,Antiarrhythmicagents,Anti-anginalagents,

Antihypertensiveagents,peripheralVasodilatorsanddrugsusedinatherosclerosis.

(viii)Drugsactingonthebloodandbloodformingorgans.Haematinics,coagulantsand

anticoagulants,Haemostatic,Bloodsubstitutesandplasmaexpanders.

(ix) Drugsaffectingrenalfunction:Diureticsandanti-diuretics. 14



15

(x) Hormonesandhormoneantagonists-Hypoglycemicagents,Anti—thyroiddrugs,sex

hormonesandoralcontraceptives,corticosteroids.

(xi) Drugsactingondigestivesystem:Carminativesdigestants,Bitters,Antacidsanddrugs

usedinpepticulcer,purgatives,andlaxatives,Antidiarrohoeals,Emetics,Anti-emetics,and

Antispasmodics.

(xii)Chemotherapyofmicrobialdiseases:Urinaryantiseptics,sulphonamides,penicillin,

streptomycin,Tetracyclinesandotherantibiotics.Anti-tubercularagents,Antifungalagents,

antiviraldrugs,anti-leproticdrugs.

(xiii)Chemotherapyofprotozoaldiseases:Anthelminticdrugs.

(xiv)Chemotherapyofcancer.

(xv)Disinfectantsandantiseptics.

Note:Adetailedstudyoftheactionofdrugsoneachorganisnotnecessary.

PHARMACEUTICALJURISPRUDENCE

1. OriginandnatureofpharmaceuticallegislationinIndia.Itsscopeandobjectives.Evolutionof

the“Conceptofpharmacy”asanintegralpartoftheHealthcaresystem.

2. PrinciplesandsignificanceofprofessionalEthics.Criticalstudyofthecodeofpharmaceutical

EthicsdraftedbypharmacycouncilofIndia.

3. PharmacyAct,1948-TheGeneralstudyofthepharmacyActwithspecialreferencetoEducation

Regulations,Workingofstateandcentralcouncils,constitutionofthesecouncilsandfunctions,

RegistrationproceduresundertheAct.

4. TheDrugsandCosmeticsAct,1940-GeneralstudyoftheDrugsandcosmeticsActandtheRules

thereunder.Definitionsandsalientfeaturesrelatedtoretailandwholesaledistributionofdrugs.

ThepowersofInspectors,thesamplingproceduresandtheprocedureandformalitiesinobtaining

licensesundertherule.Facilitiestobeprovidedforrunningapharmacyeffectively.Generalstudyof

thescheduleswithspecialreferencetoschedulesC,C-1,F,G,J,H,PandXandsalientfeaturesof

labelingandstorageconditionsofdrugs.

5.TheDrugsandMagicRemedies(objectionableAdvertisement)Act,1954-Generalstudyofthe

Act,objectives,specialreferencetobelaidonAdvertisements,magicremediesandobjections1and

permittedadvertisements-diseaseswhichcannotbeclaimedtobecured.

6. NarcoticDrugsandpsychotropicsubstancesAct,1985-Abriefstudyoftheactwithspecial

referencetoitsobjectives,offencesandpunishment.

7. Briefintroductiontothestudyofthefollowingacts:

(1) LatestDrugs(pricecontrol)orderinforce.

(2) PoisonsAct1919(asamendedtodate)

(3) MedicinalandToiletpreparations(exciseDuties)Act,1955(asamendedtodate)

(4) MedicalTerminationofPregnancyAct,1971(asamendedtodate)



DRUGSTOREANDBUSINESSMANAGEMENT

1. Introduction-Trade,Industryandcommerce,Functionsandsubdivisionofcommerce,Introduction

toElementsforEconomicsandManagement.

2. FormsofBusinessOrganizations

3. ChannelsofDistribution.

4. DrugHouseManagement-selectionofsite,spaceLay-outandlegalrequirements.Importanceand

objectivesofpurchasing,selectionofsuppliers,creditinformation,tenders,contractsandprice

determinationandlegalrequirementsthereto.Codification,handlingofdrugstoresandotherhospital

supplies.

5. InventoryControl-objectsandimportance,moderntechniqueslikeABC,VEDanalysis,theleadtime,

inventorycarryingcost,safetystock,minimumandmaximumstocklevels,economicorderquantity,

scrapandsurplusdisposal.

6. Salespromotion,MarketResearch,Salesmanship,qualitiesofasalesman,Advertisingand

WindowDisplay.

7. BankingandFinance-Serviceandfunctionsofbank,Financeplanningandsourcesoffinance.

8. Introductiontotheaccountingconceptsandconventions.DoubleentryBookKeeping,Different

kindsofaccounts.

9. CashBook.

10.GeneralLedgerandTrialBalance.

11.ProfitandLossAccountandBalanceSheet.

12.Simpletechniquesofanalyzingfinancialstatements.IntroductiontoBudgeting.

HOSPITALANDCLINICALPHARMACY

PART-I:HOSPITALPHARMACY

1. Hospital-Definition,Function,classificationsbasedonvariouscriteria,organization,Management

andhealthdeliverysysteminIndia.

2. HospitalPharmacy:

a.Definition

b.FunctionsandobjectivesofHospitalpharmaceuticalservices.

c. Location,Layout,Flowchartofmaterialsandmen.

d.Personnelandfacilitiesrequirementsincludingequipmentsbasedonindividualandbasic

needs.

e. RequirementsandabilitiesrequiredforHospitalpharmacists.

3. DrugDistributionsysteminHospitals:

a. Out-patientservice

b. In-patientservices-TypesofservicesdetaileddiscussionofunitDosesystem,Floorwardstock

system,satellitepharmacyservices,centralsterileservices,Bedsidepharmacy. 16



4. Manufacturing:

a. Economicalconsiderations,estimationofdemand.

b. Sterilemanufacture-Largeandsmallvolumeparenterals,facilities,requirements,layout

productionplanning,man-powerrequirements.

c. Non-sterilemanufacture-Liquidorals,externals,Bulkconcentrates.

d.Procurementofstoresandtestingofrawmaterials.

e. NomenclatureandusesofsurgicalinstrumentsandHospitalEquipmentsandhealthaccessories.

5. P.T.C.(PharmacyTherapeuticCommittee)

6. HospitalFormularysystemandtheirorganization,functioning,composition.

7. DrugInformationserviceandDrugInformationBulletin.

8. Surgicaldressinglikecotton,gauze,bandagesandadhesivetapesincludingtheirpharmacopoeial

testsforquality.Otherhospitalsupplyeg.I.V.sets,B.G.sets,Ryalstubes,Catheters,Syringes,etc.

9. Applicationofcomputersinmaintenanceofrecords,inventorycontrol,medicationmonitoring,

druginformationanddatastorageandretrievalinhospitalretailpharmacyestablishment.

PARTII:CLINICALPHARMACY

10.IntroductiontoClinicalpharmacypractice:Definition,scope.

11.Moderndispensingaspects-Pharmacistsandpatientcounselingandadvicefortheuseofcommon

drugs,medicationhistory.

12.CommondailyterminologyusedinthepracticeofMedicine.

13.Disease,manifestationandPatho-physiologyincludingsalientsymptomstounderstand

thedisease

likeTuberculosis,Hepatitis,RheumatoidArthritis,Cardio-vasculardiseases,Epilepsy,Diabetes,Peptic

Ulcer,Hypertension.

14.Physiologicalparameterswiththeirsignificance.

15.DrugInteractions:

a.Definitionandintroduction.

b.MechanismofDrugInteraction.

c. Drug-druginteractionwithreferencetoanalgesics,diuretics,cardiovasculardrugs,Gastro

intestinalagents.VitaminsandHypoglycemicagents.

d.Drug-foodinteraction.

16.AdverseDrugReaction:

a.Definitionandsignificance.

b.Drug-InduceddiseasesandTeratogenicity.

17. Drugs in Clinical Toxicity: Introduction, general treatment of poisoning, systemic antidotes,

Treatment of insecticide poisoning, heavy metal poison, Narcotic drugs, Barbiturate, Organo

phosphoruspoisons.

18.Drugdependences,drugabuse,addictivedrugsandtheirtreatment,complications.

19.Bio-availabilityofdrugs,includingfactorsaffectingit.

17

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