Cutaneous Fungal Infectionskau.edu.sa/Files/0001143/Files/22600_fungus.pdf · 2009-04-20 ·...
Transcript of Cutaneous Fungal Infectionskau.edu.sa/Files/0001143/Files/22600_fungus.pdf · 2009-04-20 ·...
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Cutaneous Fungal Infections
Dr Sameer ZimmoAssociate Professor of DermatologyAssociate Professor of Dermatology
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Cutaneous Fungal Infections
oDermatophytosis - "ringworm" disease of theoDermatophytosis ringworm disease of the nails, hair, and/or stratum corneum of the skin caused by fungi called dermatophytescaused by fungi called dermatophytes. oDermatomycosis - more general name for any skin disease caused by a fungusany skin disease caused by a fungus.
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Species found in different anamorphic genera are the cause of different clinicalgenera are the cause of different clinical
manifestations of ring worm
• Microsporum - infections on skin and hair p(not the cause of TINEA UNGUIUM)
• Epidermophyton infections on skin and• Epidermophyton - infections on skin and nails (not the cause of TINEA CAPITIS)
• Trichophyton - infections on skin, hair, and nails.
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M j f iMajor sources of ringworm infectioninfection
• Schools, military camps, prisons. • Warm damp areas (e.g., tropics, moisture
accumulation in clothing and shoes)accumulation in clothing and shoes).• Animals (e.g., dogs, cats, cattle, poultry,
t )etc.).
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Clinical manifestations of ringworm infections are called different names oninfections are called different names on
basis of location of infection sites• tinea capitis - ringworm infection of the head,
scalp, eyebrows, eyelashes f f• tinea corporis - ringworm infection of the body
(smooth skin)• tinea cruris ringworm infection of the groin• tinea cruris - ringworm infection of the groin
(jock itch) • tinea unguium - ringworm infection of the nailstinea unguium - ringworm infection of the nails • tinea barbae - ringworm infection of the beard • tinea manuum - ringworm infection of the handtinea manuum ringworm infection of the hand • tinea pedis - ringworm infection of the foot
(athlete's foot) ( )
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Tinea corporis body ringwormTinea corporis – body ringworm
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Tinea Cruris Jock ItchTinea Cruris – Jock Itch
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Tinea CapitisTinea Capitis
Gray PatchGray Patch
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Ectothrix and EndothrixEctothrix and Endothrix
Fluorescing hair (under Wood's lamp) is seen in dogs and cats i f t d ith d t h tinfected with some dermatophytes
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DERMATOPHYTESDERMATOPHYTES
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Tinea Unguium Nail InfectionTinea Unguium – Nail Infection
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DiagnosisDiagnosis
• Woods lamb examination. • KOH examination: MicroscopicKOH examination: Microscopic
examination of slides of skin scrapings, nail scrapings and hair Often tissuenail scrapings, and hair. Often tissue suspended in 10 % KOH solution to help clear tissue.
• Culture: Isolation of the fungus fromCulture: Isolation of the fungus from infected tissue.
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145145
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140140
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Microsporum canisTeleomorph: Arthroderma otaeTeleomorph: Arthroderma otae
http://www.doctorfungus.org/thefungi/microsporum_canis.htmhttp://www.mycology.adelaide.edu.au/Fungal_Descriptions/Dermatophytes/Microsporum/Microsporum_canis.html
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Microsporum gypseumMicrosporum gypseum
http://www.mycology.adelaide.edu.au/Fungal_Descriptions/Dermatophytes/Microsporum/Microsporum_gypseum.htm
http://www.doctorfungus.org/thefungi/microsporum_gypseum.htm
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TreatmentTreatment
• Topical – Azoles e.g., Canasten, Daktarin, Nizoralg , , ,– Ally amine e.g., Lamifen.
• Systemic y– Azoles e.g. Sporanox, Diflucan.
Ally amine e g Lamifen– Ally amine e.g., Lamifen