Samuel P. Gilmore28 Westhampton Way University of Richmond, VA 23173 215.704.9183 samuel.gilmore@richmond.edu

EDUCATIONUniversity of Richmond, Richmond, VA. May 2017Bachelor of Science in Biology, BIOL GPA: 3.7, General GPA: 3.49

Biology Honors ProgramHonors: Dean’s List: Fall 2015 – Spring 2016

Relevant Courses: BIOL 199 Genes, Neurons, and Behavior, BIOL 201 Genetics, BIOL 225 Evolution, BIOL 205 Cell Biology, BIOL 229 Microbiology, BIOL 307 Advanced Cell and Molecular Biology, BIOL 324 Molecular Virology, BIOL 354 Biological Basis of Neurodegenerative Disease, BIOL 390 Advances in Biology: Stem Cells and Ion Channels, CHEM 141 Intro Chemistry: Structure, Dynamics, and Synthesis, MATH 211 Calculus I, MATH 212 Calculus II, CHEM 205 Organic Chemistry I, CHEM 206 Organic Chemistry II, MATH 209 Intro to Statistical Modeling, PSYC 200 Methods and Analyses

PROFESSIONAL EXPERIENCESummer Research Fellow, University of Richmond, Department of Biology (Summer, 2015)

o Worked with Dr. Krista Stenger on studying the effects of a novel microtubule depolymerizer on the NF-kB pathway and, therefore, inflammation in mouse macrophages.

o Specifically, studied effects of an experimental microtubule depolymerizer and potential chemotherapeutic on the inflammatory signaling processes of the cell in order to characterize NF-kB translocation into the nucleus of activated macrophages.

Intern, Scheie Eye Institute, Philadelphia, Pa. Summers 2009-2011o Provided office aid to employees and Doctors: data entry, filing, mailing, and

organization.Volunteer: 2013-Present

o Assistant Program/Volunteer Coordinator, Shalom Farms, Richmond VA (2015-Present)o Intake Aide and Spanish Translator, Crossover Healthcare Clinic, Richmond, VA (2013-

2015)

RESEARCH/PUBLICATIONSUndergraduate Research Fall 2014 – Fall 2016 (ongoing) Undergraduate Research Associate, Stenger Lab, University of Richmond, VA

o Cellular and Molecular Immunological research studying the NF-kB pathway as implicated in the inflammatory response of mouse macrophages to bacterial markers. Notably, investigation into the translocation of NF-kB from the cytoplasm to the nucleus in these cells as mediated by microtubules.

o Currently writing a paper for publication: A pyrrole-based microtubule-depolymerizing compound reduces pro-inflammatory signaling in RAW264.7 macrophages

o Poster Presentations:- University of Richmond Summer Research Symposium (20151)- University of Richmond Student Research Symposium (20142, 20151)- Triangle Cytoskeletal Meeting, American Society for Cell Biology (20163)- American Society for Cell Biology Annual Meeting (20163)

Honors and Awards: Biology Honors Program, University of Richmond (in progress) Bonner Scholarship (2013 – Present), University of Richmond, Richmond, VA. Presidential Academic Scholarship (2013 – Present), University of Richmond, Richmond,

VA.

POSTER/PUBLICATION REFERENCES

[1] Samuel P. Gilmore, Anna Gonye, Elizabeth Li, and Dr. Krista Stenger. (2015) Effect ofa Novel Poly-Substituted Pyrrole NT-07-16 on the NF-kB Pathway and InflammatoryResponse in RAW 264.7 Macrophages. (poster; a continuation from the poster below)

[2] Samuel P. Gilmore, Anna Gonye, Elizabeth Li, and Dr. Krista Stenger. (2014) Effect ofa Novel Poly-Substituted Pyrrole NT-07-16 on the NF-kB Pathway and InflammatoryResponse in RAW 264.7 Macrophages. (poster)

[3] Samuel P. Gilmore, Anna Gonye, Elizabeth Li, and Dr. Krista Stenger. (2016) A Pyrrole-Based Microtubule-Depolymerizing Compound Reduces Pro-Inflammatory Signaling in RAW264.7 Macrophages. (poster)

LABORATORY/COMPUTER SKILLS Confocal Microscopy Fluorescence Microscopy ELISA Assay ImageJ Analysis Microorganism culturing and harvesting Immunocytochemistry and assorted biochemical measuring/analysis techniques Gel Electrophoresis and Western Blotting Microtome Fixing, Sectioning, and Analysis GraphPad PRISM Ample experience with journals/library research including PubMed, JStor, Sage, Etc. Internet, Microsoft Office Word, Powerpoint, Excel.

RESEARCH INTERESTS The interactions of the immune system and its components, specifically NF-kB, with

proteins/molecules implicated in neurodegenerative diseases such as Parkinson’s, Alzheimer’s, Machado-Joseph’s Disease, Huntington’s, ALS, etc.

Binding kinetics and protein conformational changes (due to mutation or external influence) of proteins implicated in neurodegeneration, as well as possible therapeutics and treatments for afflicted individuals.

Mechanisms and pathology of human disease, both genetic and infectious.

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