CURRICULUM VITAE: ZAIN GUDURU, M.D

CONTENT ORGANIZATION

I. GENERAL INFORMATION

II. EDUCATION

III. PROFESSIONAL EXPERIENCES

IV. ACADEMIC APPOINTMENTS

V. HOSPITAL or CLINICAL APPOINTMENTS

VI. CONSULTING ACTIVITIES

VII. TEACHING ACTIVITIES

VIII. ADVISING ACTIVITIES IX. ADMINISTRATIVE ACTIVITIES & UNIVERSITY SERVICE

X. SPECIAL ASSIGNMENTS

XI. HONORS & AWARDS

XII. PROFESSIONAL ACTIVITIES, PUBLIC SERVICE & PROFESSIONAL DEVELOPMENT

XIII. SPEAKING ENGAGEMENTS

XIV. RESEARCH & INTELLECTUAL CONTRIBUTIONS

XV. OTHER ACTIVITIES

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Date Prepared: 14 April 2021

CURRICULUM VITAE

ZAIN GUDURU, MDAssistant professor, Clinical Title Series

Department of NeurologyUniversity of Kentucky College of Medicine

UK HeathCare

I. GENERAL INFORMATION

Office Address 740 S Limestone St, Suite # J 464Lexington, KY 40515.

Email zain.guduru@uky.eduzain2811@gmail.com

Telephone (602) 758-7459Fax (859)-323-5943

Professional Licensure

12/2010-present Indian Medical Council, IndiaAndhrapradesh Medical Council, India.

07/2012-present National Provider Identification. 121529139806/2013-06/2016 Pennsylvania Board of Medical Licensure.

Graduate Medical Trainee. MT20479105/2016-12/2016 Pennsylvania Board of Medical Licensure. MD45795403/2017-02/2022 Kentucky Board of Medical Licensure. 49966. 07/2017-09/2022 United States Dept. of Justice Drug Enforcement

Administration. FG6713691

Board Certification

07/2011 Educational Council for Foreign Medical Graduates (ECFMG) Certificate. 07956717

09/2016 American Board of Psychiatry and Neurology, Inc. Diplomate, Neurology

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Research Certification

07/2013-present Collaborative Institutional Training Initiative (CITI). 4033207

09/2016-present Movement Disorders Society-Unified Parkinson’s Disease Rating Scale (UPDRS)

09/2016-present Unified Dyskinesia Rating Scale (UDysRS)09/2016-present Unified Dystonia Rating Scale (UDRS)09/2016-present Clinical Global Impression Scale (CGI-S)07/2017-06/2023 GCP certification for clinical trials involving

investigational drugs. 3622860907/2019-07/2022 Group 1 Biomedical Investigators and Key Personnel.

2418182501/2021-01/2022 Responsible Conduct of Research (Basic Course).

40250209

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II. EDUCATION

UndergraduateNone (Undergraduate degree not required prior to medical school in India).

Professional/Graduate

08/2004-05/2009 MBBS from Rangaraya Medical College, NTR University of Health Sciences, Andhrapradesh, India.

05/2009-12/2010 Mandatory Internship (part of MBBS), Gandhi Medical College, Hyderabad, India.

Post-Graduate

07/2012-06/2013 Preliminary Internal Medicine Residency. Montefiore Wakefield Hospital, Albert Einstein College of Medicine, Bronx, NY.

07/2013-06/2016 Neurology Residency. Allegheny General Hospital, Pittsburgh, PA.

07/2016-06/2017 Movement Disorders Fellowship. Augusta University, Augusta, GA.

ContinuingCME credit hours2016-now: 286.

CME Conferences attended

1 04/2015 67th American Academy of Neurology Annual Meeting, Washington DC.

2 04/2016 MDS-PAS Movement Disorders School for Neurology Residents, Atlanta, GA.

3 04/2016 68th American Academy of Neurology Annual Meeting, Vancouver, BC, Canada.

4 07/2016 A comprehensive review of Movement Disorders for the clinical practitioner. International Parkinson and Movement Disorders Society, Aspen, CO.

5 02/2017 1st Movement Disorders Society-Pan American Section (MDS-PAS) Parkinson's Disease Congress, Miami, FL.

6 04/2017 69th American Academy of Neurology Annual Meeting, Boston, MA

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7 10/2017 2017 Bluegrass Regional Movement Disorders Symposium, Lexington, KY

8 04/2018 70th American Academy of Neurology Annual Meeting, Los Angeles, CA.

9 05/2018 2018 Practical Update in Neurology & Neurosurgery, Lexington, KY.

10 10/2018 22nd International Congress: International Parkinson and Movement Disorders Society, Hong Kong.

11 04/2019 71st American Academy of Neurology Annual Meeting, Philadelphia, PA

12 05/2019 2019 Practical Update in Neurology & Neurosurgery, Lexington, KY.

13 06/2019 2019 Bluegrass Regional Movement Disorders Symposium, Indianapolis, IN.

14 09/2019 23rd International Congress: International Parkinson and Movement Disorders Society, Nice, France.

15 05/2020 2020 Practical Update in Neurology & Neurosurgery, Lexington, KY.

16 08/2020 A Comprehensive Review of Movement Disorders for the Clinician. Virtual Course by International Parkinson and Movement Disorders Society.

17 09/2020 24th International Congress: International Parkinson and Movement Disorders Society. Virtual Conference.

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III. PROFESSIONAL EXPERIENCES

07/2017 to present University of Kentucky Health CareLexington, KYAssistant Professor, Department of Neurology. Full time.

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IV. ACADEMIC APPOINTMENTS07/2017-present University of Kentucky

Lexington, KYAssistant Professor, Clinical Title Series, non-tenure track,full time. Department of Neurology.

Visiting Professorship

09/2018: Narayana Medical College, Nellore, Andhrapradesh, India. Included review of development of research, collaboration efforts with UK, medical students interaction about career goals post-graduation and presented Grand Rounds once on 09/10/2018, “Dopamine Synthesis Defects.”

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V. HOSPITAL OR CLINICAL APPOINTMENTS

07/2017-Present University of Kentucky A.B. Chandler Hospital, Lexington, KY.Staff Neurologist, Department of Neurology.

07/2017-Present University of Kentucky Good Samaritan Hospital, Lexington, KY. Staff Neurologist, Department of Neurology.

07/2017-06/2020 Rockcastle Regional Hospital, Mt. Vernon, KY.Consulting Staff Privileges, Neurology.

07/2017-06/2020 Good Samaritan Clinic, Lexington, KY. Staff Privileges.

07/2018-Present Federal Medical Center, Lexington, KY. Consulting Staff Privileges (Telemedicine).

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VI. CONSULTING ACTIVITIES

Local, State/Regional

01/2021-present: Lake Cumberland Regional HospitalSomerset, KYDirector, Neurology DidacticsInternal Medicine & Family Medicine Residency Programs.

National/International

07/2019-present Narayana Medical College, Narayana Institutions, Nellore, Andhrapradesh, India. Medical college Advisor.

07/2019-present American Academy of Neurology Consortium of Neurology Program Directors (CNPD).Member.

10/2019-present Narayana Medical College, Narayana Institutions, Nellore, Andhrapradesh, India. International advisory member on the research advisory board.

03/2021-present Parkinson’s Study Group (PSG) Biomarkers Working Group. Member.

03/2021-present Parkinson’s Study Group (PSG) Non-motor symptoms Working Group. Member.

05/2021 2021 International Science and Engineering Fair.Grand Awards Judge: Category of translational medical science.

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VII. TEACHING ACTIVITIES

University Faculty

1 07/2013-06/2016 Allegheny General HospitalPittsburgh, PA. Involved in teaching medical students, junior neurology and non- neurology residents during residency via lectures and direct patient care in the inpatient and outpatient settings.

2 07/2016-06/2017 Augusta UniversityAugusta, GA. Involved in teaching medical students, junior neurology and non-neurology residents during fellowship via lectures and direct patient care in the inpatient and outpatient settings.

3 07/2017-present University of Kentucky College of MedicineLexington, KY. Resident education and evaluation2017-2020, on average I have spent 6 weeks per year on our inpatient service and then 4 days a week in clinic during outpatient weeks. 07/2020-present, on average I have spent 6 weeks per year on our inpatient service and then 2 days a week in clinic during outpatient weeks.

4 07/2017-present University of Kentucky College of MedicineLexington, KY. Neurology residents-Primary mentor for 3 adult neurology residents-Secondary mentor for 3 adult neurology residents for projects. -Interactions with all adult neurology and child neurology residents include inpatient work, outpatient work in the Kentucky Neuroscience Institute and supervision of adult neurology resident clinic.

5 07/2017-present University of Kentucky College of MedicineLexington, KY. MD 832: Clerkship in Neurology, Third-year medical students

-Average of 2 students per week during my neurology inpatient service. -One medical student per week rotates in my neurology/movement disorders clinic. -Evaluation scores are on par with our departmental level.

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6 07/2017-present University of Kentucky College of MedicineLexington, KY. NEU 850: AI in Neurology, Fourth-year medical students pursuing career in neurology.

-1 student per week/ average of 3 students per year during my neurology inpatient service.

7 07/2017-present University of Kentucky College of MedicineLexington, KY. Lecturer, Movement Disorders Flipped Classroom course

- 1 lecture every 3 months-3rd year medical students (10-15 students each didactic).

8 07/2017-present University of Kentucky College of MedicineLexington, KY. Lecturer, Botulinum toxin injections workshop for movement disorders

-1 per year-32 Adult and Child Neurology Residents.

9 07/2018-present University of Kentucky College of MedicineLexington, KY. Didactic course leader, Interesting Case Conference

- 1 per month, - 32 Adult and child neurology residents.

I have started this conference as APD, with the program director in 2018.

10 07/2018-present University of Kentucky College of MedicineLexington, KY. I have volunteered every year to host students in my clinics (observership):

First year medical students, as a part of ICM1 Longitudinal Clinical Experience Program (1-2 per year)

Pre-med students, as a part of UK COM Summer Medical Observership Program (1-2 per year).

11 07/2018-present University of Kentucky College of MedicineLexington, KY. Didactic course leader, Movement Disorders Video Rounds

- 1 lecture per month- 30 Adult neurology residents, child neurology residents, medical students on neurology rotation, movement disorders APPs and Brain Restoration Center team members.

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I have started these video rounds at UK.

12 03/2019-present University of Kentucky College of MedicineLexington, KY. MD817 Neuroscience and Neuroanatomy Course Lecturer- Approach to Motor systems. (3 hours)

-1 per year-100 First year medical students (UK, Bowling Green and since 2021, Northern Kentucky students).

MD817 Neuroscience and Neuroanatomy Course Lecturer- Approach to Sleep (2 hours)

-1 per year-100 First year medical students (UK, Bowling Green and since 2021, Northern Kentucky students).

13 06/2019-present University of Kentucky College of MedicineLexington, KY. Moderator/preceptor, GME Unit level SWARM

-1 every 2 months. -32 Adult and Child Neurology Residents.

I serve as SWARM faculty champion for Department of Neurology.

14 07/2020-present University of Kentucky College of MedicineLexington, KY. Moderator, Morbidity and Mortality (M&M) Conference

- 1 every 3 months. - 27 Adult Neurology Residents.

Professional Course/Program Faculty:

1 10/2017 2017 Bluegrass Movement Disorders Symposium. Lexington, KY. Podium presentation of three movement disorders cases.

2 05/2018 University of Kentucky College of Medicine Lexington, KY. 2018 Practical Update Neurology & Neurosurgery.“Tremor.”

3 10/2018-02/2019

University of Kentucky College of Medicine Lexington, KY. Academy of Medical Educators’ Clinical Teaching Development Program.

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4 05/2019 University of Kentucky College of Medicine Lexington, KY. 2019 Practical Update Neurology & Neurosurgery. “Medical Management of Parkinson’s disease.”

5 04/2019 Vanderbilt UniversityNashville, TN. 1st Annual Junior Faculty Forum on Common Movement Disorders.

Abortive strategies for Off periods in Parkinson’s disease. Neurotoxin injections techniques.

6 06/2019 2019 Bluegrass Movement Disorders Symposium. Indianapolis, IN.

“Drug Induced Movement Disorders.” Podium presentation of three movement disorders cases.

7 05/2020 Commonwealth Neurological SocietyLouisville, KY.12th Annual Advances in Neurology“Drug Induced Movement Disorders.”

8 05/2020 University of Kentucky College of MedicineLexington, KY.2020 Practical Update in Neurology & Neurosurgery.“Recognition and management of Dystonia.”

9 11/2020-03/2021

University of Kentucky College of MedicineLexington, KY Academy of Medical Educators’ Classroom Teaching Course.

VIII.ADVISING ACTIVITIES

1 03/2018-04/2019 University of Kentucky College of Medicine

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Lexington, KY. Sadia Waheed, M.B.B.S.Research assistant in movement disorders (MDs) and MDs clinic.Achievement: Adult Neurology residency at Florid Atlantic University.

2 05/2018-06/2018 University of Kentucky College of MedicineLexington, KY. Saniya Pervin, M.B.B.S. from Kasturba medical college, India. Acting Internship for a month.Achievement: Adult Neurology residency at University of Kentucky.

3 06/2018-06/2019 University of Kentucky College of MedicineLexington, KY. Samia Jahan, M.B.B.S.Research assistant in movement disorders (MDs) and MDs clinic.

4 10/2018-04/2019 University of Kentucky College of MedicineLexington, KY. Dhanunjaya Rao Ginjupally, M.B.B.S., M.S.Visiting physician: Functional Neurosurgery in Movement Disorders.

5 04/2019-02/2020 University of Kentucky College of MedicineLexington, KY. Rani Priyanka Vasireddy, M.B.B.S.Research assistant in movement disorders (MDs) and MDs clinic.Achievement: Adult Neurology resident at University of Kentucky.

6 07/2019-08/2019 University of Kentucky College of MedicineLexington, KY. Anvesh Bhalabhadra, M.B.B.S. from Gandhi Medical College, India.Achievement: Adult Neurology residency at University of Connecticut.

7 08/2019-09/2019 University of Kentucky College of MedicineLexington, KY. Sandeep Sekhon, M.B.B.S. from Lady Harding Medical College, India.

College students

04/2019-08/2019

University of Kentucky College of MedicineLexington, KY. John MarcumRising College Sophomore (Summer Medical Observership Program).Achievement: Joined medical school at UKCOM in 2020.

PhD Doctorate

07/2019-06/2020

University of Kentucky College of MedicineLexington, KY.

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Nader El-Seblani, MD, PhD. Mentor during his PhD: work with brain restoration center on Parkinson’s disease. Achievement: Adult Neurology Residency at University of Pennsylvania.

Medical students

1 07/2018-06/2019

Dylan Ryan, 4th year medical student. Achievement: Neurology Residency at Duke University.

2 08/2018-09/2018

Timothy Libecap, first year Medical Student (MD/PhD program, Longitudinal Clinical Experience for ICM1). Achievement: American Academy of Neurology Medical Student Experience at AAN annual conference.

3 07/2019-06/2020

Molly Bates, 4th year medical student. Achievement: Neurology Residency at University of Kentucky.

4 08/2019-02/2020

Grant Austin, first year Medical Student (Longitudinal Clinical Experience for ICM1).

5 08/2019-02/2020

Kaitlyn Weyman, first year Medical Student (Longitudinal Clinical Experience for ICM1).

6 07/2020-present

Cory Owens, 4th year medical student. Achievement: Adult Neurology Residency at University of Kentucky.

7 07/2020-present

Jessica Creager, 4th year medical student. Achievement: Adult Neurology Residency at Mayo Clinic, FL.

8 07/2020-present

Andrew Welleford, 4th year medical student. Achievement: Adult Neurology Residency at University of Kentucky.

9 07/2020-present

Anthony Donigian, 3rd year medical student.

Neurology residents

1 07/2018-06/2020

Tarek Ali, MD, MA.Achievement:

Recipient of Movement Disorders Fellowship at UKCOM. Assistant Professor of Neurology at University of Kentucky

in 2021. 2 07/2018-

currentJason Chisolm, MD. Achievement: Chosen as Associate Chief Resident.

3 07/2019-current

Omar Al-Janabi, MD, PhD. Achievement: American Academy of Neurology Resident Scholarship.

4 07/2018-06/2019

Swathi Pradeep, MD. Achievement: Movement Disorders Fellowship at UT Houston.

5 07/2019-present

Gabriela Keeton, MD. Achievement: Academic chief resident, Neurology residency.

6 07/2019-present

Julie Zhou, MD. Mentor for quality improvement project: Topic: “Resident documentation Education for accurate billing.”

7 07/2020-present

Kini Tonse, MD. Mentor for quality improvement project: Topic: “Virtual Didactics: feedback questionnaire.”

8 07/2018- Fawad Yousuf, MD. Achievement:

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present 02/2021: University of Kentucky Graduate Medical Education Resident of the Month, American Academy of Neurology Resident Scholarship.

9 07/2020-present

Paige Sutton, MD. Achievement: Clinical Chief Resident, Dept of Neurology, University of Kentucky.

10 07/2020-present

Kyle Darpel, MD.Achievement: Chief Resident, Dept of Neurology, University of Kentucky.

11 01/2020-present

Pinar Coskun, MD. Achievement: American Academy of Neurology Futures in Neurologic Scholar.

12 07/2020-present

Chintan Rupareliya, MD.

13 07/2020-present

Wenyang Li, MD.

Neurosurgery resident

07/2019-present Tripp Hines, MD

Movement Disorders Fellow

07/2020-present Tarek Ali, MD, MA. Achievement: Joining as Assistant Professor of Neurology at University of Kentucky in 07/2021.

Invited Referee for Academic Appointment, Promotion or Tenure

Recommendation for appointment at Rank of Assistant Professor, Clinical title series. Department of Neurology University of Kentucky College of Medicine, Lexington, KY

06/2019 Recommendation for appointment to rank of Assistant Professor. 04/2020 Recommendation for appointment to rank of Associate Professor. 07/2020 Recommendation for appointment to rank of Assistant Professor 10/2020 Recommendation for appointment to rank of Assistant Professor.10/2020 Recommendation for appointment to rank of Associate Professor. 11/2020 Recommendation for appointment to rank of Assistant Professor.

Department of Neurology Nizam’s Institute of Medical Sciences (NIMS), Hyderabad, India.

02/2020-present External Examiner for Ph.D. in Neurology.

Invited ACGME program review at University of Kentucky College of Medicine

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08/2018-12/2018: Reviewed 6 residency/fellowship programs. 01/2019-12/2019: Reviewed 7 residency/fellowship programs.01/2020-12/2020: Reviewed 6 residency/fellowship programs.

IX. ADMINISTRATIVE ACTIVITIES & UNIVERSITY SERVICE

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Department

University of Kentucky College of MedicineLexington, KY.

Administration & Clinical Operations

07/2018- present Chair of Adult Neurology Residency Program Evaluation Committee (PEC).

07/2018-present Member of Adult Neurology Residency, Recruitment committee. Annually review about 600 applications and select 60-80 candidates for interviews.

07/2018-present Member of Adult Neurology Residency, Clinical Competency committee.

07/2019-present Teleneurology rotation director, Adult Neurology Residency.07/2020-present Resident Research rotation course co-director, Adult Neurology

Residency.

Education & Research

07/2020-present Moderator, Department of Neurology, Morbidity & Mortality Conference.

07/2020-present GME unit level SWARM Champion, Department of Neurology.

College

University of Kentucky College of MedicineLexington, KY.

Administration & Clinical Operations

1 09/2017-09/2018

Acting Internship director, Adult Neurology.

2 12/2017-Present Faculty Advisor for Student Interest Group in Neurology (SIGN) and SIGN leader.

3 03/2018-09/2018

Advanced Development Director, Adult Neurology.

4 07/2018-Present Member of Program Review Committee, University of Kentucky Graduate Medical Education (GME).

5 09/2018-07/2020

Associate Program Director, Adult Neurology Residency (ACGME approved).

6 07/2019 Played an important role in facilitating the collaboration of University of Kentucky and Narayana Medical College and hospital (India): Clinical Student Exchange Agreement.

7 07/2019-present Member of Pain Medicine Fellowship Program Evaluation Committee, University of Kentucky College of Medicine.

8 02/2020-Present Faculty advisor for American Academy of Neurology (AAN) SIGN shadow-me kick off program, University of Kentucky College of Medicine.

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9 07/2020-Present Member of Admissions Interviewer, University of Kentucky College of Medicine.

10 07/2020-Present Program Director, Adult Neurology Residency (ACGME approved).

Education & Research

11 07/2020-Present Member of Education Sub-committee, University of Kentucky Graduate Medical Education.

Medical Center

University of Kentucky College of MedicineLexington, KY.

07/2019-present

Administration & Clinical Operations

Member of Patient experience committee, Kentucky Neuroscience Institute.

Education & Research

07/2017-Present Member of Brain Restoration Committee (BRC), University of Kentucky: A multidisciplinary clinical and scientific research team to direct clinical trials and pre-clinical science research to find new treatments and identify biomarkers for Parkinson’s disease.

X. SPECIAL ASSIGNMENTS

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XI. HONORS & AWARDS

1 06/2014 Travel Award, Pennsylvania Neurological society annual meeting. 2 02/2015 Travel Award, American Society of Neuroimaging. 3 04/2015 Resident scholarship award, American Academy of Neurology annual

meeting.

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4 01/2017 Travel Award, 1st MDS-Pan-American Society (MDS-PAS) Congress. 5 04/2017 Future Clinical Researchers in Neurology and Neuroscience Scholarship,

American Academy of Neurology (AAN) annual meeting.6 10/2017 New member scholarship, Huntington’s study group (HSG) annual

event. 7 08/2018 Travel fellowship award, Parkinson’s Study Group (PSG) annual

meeting and symposium.8 09/2018 Travel Award, Movement Disorders Society (MDS) International

Congress. 9 10/2018 UK Neurology Pilot Grant (20,000$). A pilot study for quantification of

balance deficits in Parkinson’s disease after deep brain stimulation. Pilot trial at University of Kentucky, as a Principal-investigator.

10 02/2019 CCTS (Center for clinical and translational science) Pilot grant (46,000$). A pilot study to examine apomorphine-induced BOLD activation in patients with Parkinson’s disease. Pilot trial at University of Kentucky, as a Principal-investigator.

11 05/2020 Travel fellowship award, Parkinson’s Study Group (PSG) annual meeting and symposium. But conference was cancelled because of COVID.

12 02/2021 Academy of Medical Educators Excellence in Medical Education Award in the area of Teaching.

13 03/2021 Patient donation to me of $10,000 to spend on neurology residency program.

XII. PROFESSIONAL ACTIVITIES, PUBLIC SERVICE & PROFESSIONAL DEVELOPMENT

Membership:

1 10/2010-present Andhrapradesh Medical Council.2 12/2013-present American Academy of Neurology. 3 12/2014-12/2015 American Epilepsy Society.4 08/2016-present International Parkinson’s and Movement Disorders Society5 07/2017-present Association of Indian Neurologists in America.

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6 08/2017-present Commonwealth Neurological Society7 10/2017-present Huntington’s Study Group.8 10/2017-present Parkinson’s Study Group.9 08/2020-present American Neurological Association.

Regional:

01/2021-present Director, Neurology Didactics, Internal Medicine & Family Medicine Residency Programs, Lake Cumberland Regional Hospital, Somerset, KY.

01/2021-present Co-Director, Residents and Fellows Section, Commonwealth Neurological Society.

National/International:

06/2017-04/2019 Residents & Fellows (R&F) section leader, Association of Indian Neurologists in America (AINA)

07/2018-present Member of AAN Synapse Connected Community: Consortium of Neurology Program Directors.

08/2018-present Member of Special interest groups: Neurosurgery Disorders Special Interest Group, Pediatric Movement Disorders Special Interest Group, Young Members Group, International Movement Disorders Society.

09/2019-present International advisory member on the research advisory board of Narayana Medical Institutions, Nellore, India.

04/2021-04/2022 Selected as “Mentee” for 2021 American Academy of Neurology Director Mentorship Leadership Program. Mentor: Dr. Sachin Kedar (Professor, Dept of Neurology, University of Nebraska).

04/2021-04/2022 Selected as “Mentor” for Neurology Resident and Fellow Section (RFS) Mentored review program.

Review panel:

12/2019 University of Kentucky Center for Clinical and Translational Science (CCTS) grant reviewer. Early career award.

12/2019 University of Kentucky Center for Clinical and Translational Science (CCTS) grant reviewer. High impact award.

07/2020 American Neurological Association annual meeting abstracts reviewer.

Journal Peer-Reviewing

Ad Hoc Reviewer:

07/2019-present CNS Spectrums, Cambridge University Press. 07/2019-present Drugs, Adis journals, Springer Publisher. 08/2019-present The journal of clinical pharmacology, Wiley Publisher. 11/2019-present Journal of Geriatric Psychiatry and Neurology, SAGE publisher.

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02/2020-present Clinical Nephrology, Dustri-Verlag publisher04/2020-present Movement Disorders Clinical Practice, Wiley Publisher.07/2020-present Journal of Movement Disorders, Korean Movement Disorders

Society.

Media Contributions

1. 11/17/2017 Bleacher Report. “UK QB’s Triumph over Tourette’s May Be Hard to believe, but It’s inspiring many.” Expert opinion of Tourette’s syndrome. https://bleacherreport.com/articles/2744644-uk-qbs-triumph-over-tourettes-may-be-hard-to-believe-but-its-inspiring-many

2. 04/02/2019 Association of Indian Neurologists in America (AINA) interviews 2018 lifetime achievement award winner: Dr. Vinay Chaudhry. https://www.4aina.com/Latest-news?pg=5

3. https://www.4aina.com/resources/Documents/Dr.%20Chaudhry%20AINA %20interview.m4a

4. 04/10/2019 UK health care: “Listen: How innovative treatments are changing the outlook for Parkinson's patients.” https://ukhealthcare.uky.edu/wellness-community/blog/listen-how-innovative-treatments-are-changing-outlook-parkinsons-patients

5. 02/12/2020 UK Now, UK Healthcare magazine: “New to America and Facing a rare condition, patient credits UK for regaining ability to walk.” https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fuknow.uky.edu%2Fuk-healthcare%2Fnew-america-and-facing-rare-condition-patient-credits-uk-regaining-ability-walk&data=02%7C01%7Czain.guduru%40uky.edu%7C0a7bba34967e49fbec0508d7afd586dd%7C2b30530b69b64457b818481cb53d42ae%7C0%7C0%7C637171203928768646&sdata=nzbM0rWQ%2F4aeE4JRqsWflTBmT0l7k0D5PbXQWufCNdU%3D&reserved=0

6. 03/17/2020 UK Now, UK Healthcare magazine: “A pilot study to examine apomorphine-induced BOLD activation in patients with Parkinson’s disease. Pilot trial at University of Kentucky, as a Principal-investigator. http://uknow.uky.edu/research/uk-research-could-help-predict-progression-parkinsons-disease

7. 03/25/2020 Parkinson’s News Today. “Study to Test MRI Technique for Possible Early Parkinson’s Diagnosis.” https://parkinsonsnewstoday.com/2020/03/25/study-to-test-mri-technique-for-early-parkinsons-diagnosis-university-kentucky/

8. 08/05/2020 University of Kentucky Health Care Interview. https://www.youtube.com/watch?v=H6RIwKRrdwQ

Professional Development

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International

1. 01/2018: 3rd annual conference of the Movement Disorders Society of India (MDSICON), Hyderabad, Telangana, India.

2. 09/2018: Annual International Congress, Movement Disorders Society, Hong Kong. 3. 09/2019: Annual International Congress, Movement Disorders Society, Nice, France. 4. 09/2020: Annual International Congress, Movement Disorders Society, Virtual

Conference.

National

1. 04/2015: 67th American Academy of Neurology Annual Meeting, Washington DC. 2. 04/2016: 68th American Academy of Neurology Annual Meeting, Vancouver, BC,

Canada.3. 04/2017: 69th American Academy of Neurology Annual Meeting, Boston, MA.4. 04/2018: 70th American Academy of Neurology Annual Meeting, Los Angeles, CA. 5. 05/2018: Parkinson’s Study Group 29th annual meeting and 31st annual symposium, Jersey

City, NJ. 6. 11/2018: 31st Huntington’s Study Group Annual event, Houston, TX. 7. 04/2019: 71st American Academy of Neurology Annual Meeting, Philadelphia, PA. 8. 04/2019: Parkinson’s Study Group 30th annual meeting and 32nd annual symposium,

Phoenix, AZ. 9. 04/2019: Forum on Common Movement Disorders for Junior Faculty. Vanderbilt

University, Nashville, TN. Offered 28 AMA PRA Category 1 credits, two American Board of Psychiatry and Neurology approved Part IV Maintenance of Certification (MOC) activities.

10. 04/2020: 72nd American Academy of Neurology Annual Meeting, virtual conference.

Regional

10/2017 Bluegrass Movement Disorders Symposium, Lexington, KY.

05/2018 Practical Update in Neurology, Neurosurgery, Lexington, KY.

05/2018 10th Commonwealth Neurological Society,Louisville, KY.

05/2019 Practical Update in Neurology and Neurosurgery, Lexington, KY.

06/2019 Bluegrass Movement Disorders Symposium, Indianapolis, IN.

05/2020 12th Annual Advances in Neurology, Commonwealth Neurological Society. Virtual conference by University of Louisville, Louisville, KY.

05/2020 Practical Update in Neurology and Neurosurgery, Lexington, KY. Virtual Conference.

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University of Kentucky College of Medicine

1 11/2018-03/2019 University of Kentucky College of Medicine Academy of Medical Educators’ Clinical Teaching Development Program. Lexington, KY.

2 09/2020 Fall faculty development session: “Writing a specific aims page”, presented by Dr. Douglas Andres. Lexington, KY.

3 10/2020 Promotion and Dossier Readiness: “Tips and strategies for success”, presented by Drs. Blalock and Schumacher. Lexington, KY.

4 10/2020 Fall faculty development session: “Stress in shifting world: factors and fixes”, presented by Ms. Mareen Dennis. Lexington, KY.

5 10/2020 Faculty development session: “Individual Precepting workshop” presented by Dr. Kristy Deep. Lexington, KY.

6 10/2020 Faculty development session: “Teaching Learners in the Group”, presented by Dr. Kristy Deep. Lexington, KY.

7 10/2020 Faculty development session: “Pause, Pivot, Promotion and the pandemic: Promotion Strategies”, presented by Dr. Lisa Tannock. Lexington, KY.

8 10/2020 Faculty development session: “Effective feedback”, presented by Dr. Amber Pincavage. Lexington, KY.

9 11/2020-03/2021 University of Kentucky College of Medicine Academy of Medical Educators’ Classroom Teaching Development Program. Lexington, KY.

10 01/2021 UK Faculty development session: “Race Matters: Race, Racism & Healthcare” presented by Dr. Anita Fernander. Lexington, KY.

11 02/2021 UK Faculty development session: “Mentee up! How to get the most out of a mentoring relationship” presented by Dr. John Ragsdale. Lexington, KY.

12 04/2021 Faculty development session: “Promotion and Dosier preparation”, presented by Dr. Lisa Tannock. Lexington, KY.

13 04/2021 Faculty development session: “Should Justin T Bieber be promoted to be the Associate Professor. You be the judge”, presented by Dr. Michael Rowland. Lexington, KY.

XIII. SPEAKING ENGAGEMENTS

Local

1 05/2015 Allegheny General Hospital, Pittsburgh, PA.Department of Neurology, Research day Conference. “Medication Reduction After DBS Placement in Parkinson’s Disease.”

2 06/2015 Allegheny General Hospital, Pittsburgh, PA.Department of Neurology, Morbidity and Mortality Conference. “Acute spinal cord injury.”

3 02/2016 Allegheny General Hospital, Pittsburgh, PA.

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Combined neurology, neurosurgery, pathology and radiology conference. “Tuberculosis cerebral vasculitis with multiple small strokes.”

4 11/2016 Augusta University, Augusta, GA.Department of Neurology, Noon didactic Conference. “Cerebellar ataxia.”

5 12/2016 Augusta University, Augusta, GA.Department of Physical therapy. Noon conference. “Spinal cord disorders.”

6 12/2016 Augusta University, Augusta, GA.Department of Internal Medicine. Noon conference. “Parkinson’s disease and Parkinsonism.”

7 05/2017 Augusta University, Augusta, GA.Department of Neurology, Grand Rounds. “Dopamine Synthesis Defects.”

8 05/2017 Augusta University, Augusta, GA.Department of Neurology, Noon didactic Conference. “Deep Brain Stimulation.”

9 08/2017 University of Kentucky College of MedicineLexington, KY. Department of Neurology, Grand Rounds. “Dopamine Synthesis Defects.”

10 12/2017 University of Kentucky College of MedicineLexington, KY. Department of Neurology, Student Interest Group in Neurology (SIGN) meeting. “Neurology journey and career.”

11 12/2017 University of Kentucky College of MedicineLexington, KY. Department of Neurology, Resident Noon Conference. Fellowship panel discussion with residents to encourage them to pursue Movement Disorders career.

12 12/2017-present

University of Kentucky College of MedicineLexington, KY. Department of Neurology, Neurosurgery and Neuroscience (including neurology residents) Monthly Movement Disorders Video Rounds. This was developed and introduced by me in 2017.

13 12/2017-present

University of Kentucky College of MedicineLexington, KY. Department of Neurology. Monthly Flip class on “Introduction to Movement Disorders” for third year medical students.

14 03/2018 University of Kentucky College of MedicineLexington, KY. Department of Neurology, Resident Noon Conference. “Tremor.”

15 05/2018 University of Kentucky College of MedicineLexington, KY. 2018 Practical Update Neurology & Neurosurgery, University of Kentucky. “Tremor.”

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16 06/2018 University of Kentucky College of MedicineLexington, KY. Department of Neurology, Grand Rounds. “Gait abnormalities in Movement Disorders.”

17 07/2018 University of Kentucky College of MedicineLexington, KY. Department of Neurology, Grand Rounds. “Movement Disorders Emergencies.”

18 07/2018-present

University of Kentucky College of MedicineLexington, KY. Department of Neurology. Monthly Interesting Case Conference.

19 09/2018 University of Kentucky College of MedicineLexington, KY. Department of Physical Medicine and Rehabilitation (PMR). Morning didactic for PMR residents. “Parkinson’s disease.”

20 09/2018 University of Kentucky College of MedicineLexington, KY. Department of Pediatric Neurology. Grand Rounds. “Pediatric Movement Disorders.”

21 10/2018, 12/2019, 12/2020

University of Kentucky College of MedicineLexington, KY. Department of Neurology, Resident Noon Conference. “Botulinum toxin in dystonia.”

22 03/2019 University of Kentucky College of MedicineLexington, KY. Lecture for First year Medical Students (MD 817). “Approach to sleep.”

23 03/2019 University of Kentucky College of MedicineLexington, KY. Lecture for First year Medical Students (MD 817). “Approach to motor systems.”

24 05/2019 University of Kentucky College of MedicineLexington, KY. Practical Update Neurology & Neurosurgery.“Medical Management of Parkinson’s disease.”

25 06/2019 University of Kentucky College of MedicineLexington, KY. Department of Preventive Medicine. “Neurotoxic exposure in the worker.”

26 07/2019 University of Kentucky College of MedicineLexington, KY. Department of Pediatric Neurology. Grand Rounds. “Pediatric Movement Disorders Part 1 (tremor, parkinsonism, dystonia).”

27 08/2019 University of Kentucky College of MedicineLexington, KY. Department of Pediatric Neurology. Grand Rounds. “Pediatric Movement

28

Disorders Part 2 (tics, stereotypies, chorea, myoclonus).”28 03/2020 University of Kentucky College of Medicine

Lexington, KY. Lecture for First year Medical Students (MD 817). “Approach to sleep.”

29 03/2020 University of Kentucky College of MedicineLexington, KY. Lecture for First year Medical Students (MD 817). “Approach to motor systems.”

30 04/2020 University of Kentucky College of MedicineLexington, KY. Department of Physical Medicine and Rehabilitation (PMR). “Parkinson’s disease and atypical parkinsonism.”

31 04/2020 University of Kentucky College of MedicineLexington, KY. Department of Family Medicine. Grand Rounds. “Introduction to Movement Disorders.”

32 04/2020 University of Kentucky College of MedicineLexington, KY. Faculty meeting, Department of Neurology: “Introduction of combined general service and development of team leadership skills among senior residents.”

33 05/2020 University of Kentucky College of MedicineLexington, KY. Department of Neurology, Grand rounds. “Time is cerebellum: Immune mediated Cerebellar ataxias.”

34 05/2020 University of Kentucky College of MedicineLexington, KY. 2020 Practical Update in Neurology & Neurosurgery. “Recognition and management of Dystonia.”

35 06/2020 University of Kentucky College of MedicineLexington, KY. Faculty meeting, Department of Neurology: “What makes good feedback.”

36 07/2020 University of Kentucky College of MedicineLexington, KY. Faculty meeting, Department of Neurology: “Introduction of Research Program in Residency and Research Mentor-Mentee program.”

37 07/2020-present

University of Kentucky College of MedicineLexington, KY. Department of Neurology, Biweekly Resident-PD meeting presentations.

38 07/2020-present

University of Kentucky College of MedicineLexington, KY. Precept/Moderate Morbidity and Mortality Conference, Department of Neurology, University of Kentucky COM (4 per year).

39 07/2020- University of Kentucky College of Medicine

29

present Lexington, KY. GME level SWARM faculty champion. Precept the unit level SWARMs for adult Neurology residents (3 per year).

40 09/2020 University of Kentucky College of MedicineLexington, KY. Faculty meeting, Department of Neurology: “Introduction to Career/Academic mentor, Virtual Residency Interviews and Sub-Specialty cases in Resident Clinic.”

41 10/2020 University of Kentucky College of MedicineLexington, KY. UK SIGN: “Neurologists: A day in the life.”

42 10/2020 University of Kentucky College of MedicineLexington, KY. Department of Pediatric Neurology. Grand Rounds. “Chorea and Dystonia in Pediatric Population.”

43 12/2020 University of Kentucky College of MedicineLexington, KY. Department of Neurology, Grand Rounds. “Autoimmune/ Paraneoplastic movement disorders.”

44 02/2021 University of Kentucky College of MedicineLexington, KY. Lecture for First year Medical Students (MD 817): “Approach to motor systems.”

45 03/2021 University of Kentucky College of MedicineLexington, KY. Lecture for First year Medical Students (MD 817). “Approach to sleep.”

State/Regional

To medical professionals

1 05/2018 University of Kentucky, Lexington, KY.2018 Practical Update in Neurology & Neurosurgery: “Tremor”

2 06/2019 Bluegrass Movement Disorders Symposium, Indianapolis, IN. “Drug Induced Movement Disorders.”

3 05/2019 University of Kentucky, Lexington, KY.2019 Practical Update in Neurology & Neurosurgery: “Medical Management of Parkinson’s disease.”

4 05/2020 Commonwealth Neurological Society. 12th Annual Advances in Neurology. Virtual conference by University of Louisville, Louisville, KY. “Drug Induced Movement Disorders.”

5 05/2020 University of Kentucky, Lexington, KY.

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2020 Practical Update in Neurology & Neurosurgery: “Recognition and management of Dystonia.”

6 10/2020 Pikeville Medical Center, Pikeville, KY. Department of Neurology grand rounds: “Stroke induced movement disorders.”

7 02/2021 Lake Cumberland Hospital, Somerset, KY. Department of Internal Medicine and Family Medicine. Noon conference: “Introduction to Movement Disorders.”

To non-medical professionals

1 03/2017 Parkinson’s foundation, Augusta, GA. Lunch & Learn course for Parkinson’s disease patients and caregivers of Georgia. “Non-motor symptoms in Parkinson’s disease: Dark side of the moon.”

2 04/2017 Lake Oconee Moves, Lake Oconee, GA. Lunch & learn course for Parkinson’s disease patients and caregivers in Lake Oconee. “Non-motor symptoms in Parkinson’s disease: Dark side of the moon.”

3 05/2017 CSRA Parkinson’s support group, Augusta, GA. “Non-motor symptoms in Parkinson’s disease: Dark side of the moon.”

4 08/2017 Lexington Area Parkinson’s Support Group (LAPSG), Lexington, KY. “Non-motor symptoms in Parkinson’s disease: Dark side of the moon.”

5 04/2018 Everything is science 2018 (University of Kentucky organized regional event), Lexington, KY. “Head to head- the science of ageing and brain.”

6 02/2018 Lexington Area Parkinson’s Support Group (LAPSG), Lexington, KY. “Medication management of Parkinson’s disease.”

7 03/2018 University of Kentucky sponsored guest lecture, Lexington, KY.“Drug Induced Movement Disorders.”

8 08/2018 Rockcastle Regional Hospital, Mt Vernon, KY.“Introduction and Management of Parkinson’s disease.”

9 10/2018 Keynote speaker at “Gathering for good” (Lexington Area Parkinson’s Support Group annual meeting), Lexington, KY.“Myths and mistakes in the treatment of Parkinson’s disease.”

10 11/2018 Frankfurt Parkinson’s Support Group, Frankfurt, KY. “Medication management of Parkinson’s disease.”

11 05/2019 Curie Learning, Richmond, VA. Motivational speech for high school students who have interest in medical field. “A career as a doctor.”

12 03/2020 Lexington Area Parkinson’s Support Group (LAPSG), Lexington, KY. “Nutrition and Parkinson’s disease.”

13 04/2020 Parkinson’s International Foundation, Lexington, KY.“COVID19 and Parkinson’s Disease”

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National

1 04/2019 Vanderbilt University, Nashville, TN.1st Annual Junior Faculty Forum on Common Movement Disorders. “Abortive strategies for Off periods in Parkinson’s disease.”

2 04/2019 Vanderbilt University, Nashville, TN.1st Annual Junior Faculty Forum on Common Movement Disorders. “Neurotoxin injections techniques.”

3 2019-present Monthly Professor Movement Disorders video rounds with multiple movement disorders specialists from different regions in USA which is led by Professor Dr. Kapil D Sethi.

4 06/2020 University of Tennessee, Memphis, TN. Didactic lecture to Neurology Residents. “Dystonia and gait disorders.”

5 07/2020 University of Tennessee, Memphis, TN. Didactic lecture to Neurology Residents. “Movement Disorders Emergencies and Drug Induced Movement Disorders.”

6 01/2021 University of Tennessee, Memphis, TN. Grand rounds, Department of Neurology. “Autoimmune/ Paraneoplastic movement disorders.”

7 03/2021 University of Tennessee, Memphis, TN. Didactic lecture to Neurology Residents. “Tremor and parkinsonism.”

8 03/2021 American Society of Neuroimaging Educational Rounds, Buffalo, NY. “Neuroimaging in Movement Disorders.”

9 04/2021 University of Tennessee, Memphis, TN. Didactic lecture to Neurology Residents. “Dystonia, Chorea and tics.”

International

10/2018 Narayana Medical College, Nellore, Andhrapradesh, India. Grand Rounds. “Dopamine Synthesis Defects.”

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XIV. RESEARCH & INTELLECTUAL CONTRIBUTIONS

A. PUBLICATIONS

Peer-Reviewed Original Research in Professional, Scientific or Educational Journals

1. Ramanathan S, Rana S, Guduru Z et al. Unusual case of recurrent SMART (Stroke-like migraine attacks after radiation therapy) syndrome. Annals of Indian Academy of Neurology 2016; 19 (3); 399-401.

2. Guduru Z, Purohit A, Pu F, Rana S. Amyloid myopathy as the presenting feature of Lymphoplasmacytic Lymphoma. Annals of Indian Academy of Neurology 2017, 20 (1); 77-78.

3. Guduru Z, Morgan J, Sethi K. Anterocollis as an “off” phenomenon in Parkinson’s disease. Movement Disorders Clinical Practice Nov/Dec 2017, 4 (6); 901-902.

4. Guduru Z, Sethi KD. Bilateral facial spasm following Guillian-Barre syndrome. Tremor and other Hyperkinetic Movements 2018;8, DOI: 10.7916/D83X9PPX.

5. Quintero J E, Guduru Z, Zhang Z et al. Validations of apormorphine-induced BOLD activation correlations in hemiparkinsonian Rhesus Macaques. Neuroimage: Clinical 22 (2019) 101724.

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6. Pradeep S, Ali T, Guduru Z. Ataxia with Vitamin E deficiency with predominant cervical dystonia. Movement Disorders Clinical Practice 2019 Dec 30;7(1):100-103.

7. Avasarala J, Guduru Z, Mullins S et al. Can a diagnosis of multiple sclerosis be made without ruling out neuromyelitis optica spectrum disorder? Multiple Sclerosis & Related Disorders Vol 40, May 2020, 101949.

8. Wellford A, Guduru Z, Gerhardt G et al. RNA-Seq of Human Peripheral Nerve in Response to Injury: Distinctive Analysis of The Nerve Repair Pathways. Cell transplantation Volume 29: 1–13.

9. Bates M, Chisolm J, Avasarala J, Guduru Z. Anti-MOG and Anti-AQP4 Positive Neuromyelitis Optica Spectrum Disorder in a Patient with Myasthenia Gravis. Multiple Sclerosis and Related Disorders 44, 102205.

10.Keeton G, Ali T, Sudhakar P, and Guduru Z. A Case of Lance Adams Syndrome with See-Saw Nystagmus. Neurology 96 (5), e816-e816.

11.Vasireddy R, Sokola B, Guduru Z. New generation VMAT2 inhibitors induced parkinsonism. Clinical Parkinsonism and Related Disorders Vol 3, 2020, 100078.

12.Donigian A, Lightner D, Toupin N, Guduru Z. Acquired movement disorders secondary to giant tumefactive perivascular spaces. Journal of Movement Disorders.

13.Avasarala J, Guduru Z, Sokola B et al. Use of anti-TNF-alpha therapy in Crohn’s disease is associated with increased incidence of Multiple Sclerosis. Multiple Sclerosis and Related Disorders.

14.Gera G, Guduru Z, Quintero J et al. Gait and balance changes with investigational peripheral nerve cell therapy during deep brain stimulation in people with Parkinson’s disease. Brain Sci. 2021, 11, 500.

Non-Peer-Reviewed Articles, Editorials, Reviews in Professional, Scientific or Educational Journals

1. Guduru Z, Purohit A, Rana S. Aortic dissection presenting as anterior spinal cord syndrome. Drexel Medical Journal, 2015.

2. Guduru Z, Purohit A, Ramanathan S, Rana S. Steroid-responsive encephalopathy: Cerebral amyloid angiopathy-related inflammation. Drexel Medical Journal, 2015.

3. Guduru Z, Baser S, Leichliter T. Medication reduction after DBS placement in Parkinson’s disease. Movement Disorders Vol 32, No. 9, pp. e7.

4. Thandampallayam M, Guduru Z. Diagnostic dilemma: Anti-GAD chorea versus late onset Huntington’s disease. Commonwealth Neurological Society Residents and Fellows section, 2021.

Book Chapters:

1. “Therapy of Movement Disorders: A Case-Based Approach” on Treatment of Paroxysmal Nonkinesigenic Dyskinesia. Guduru Z and Sethi KD. Editors: Stephen Reich and Stewart Factor. May 2019. Springer International publishing.

2. “Paroxysmal movement disorders- A practical, concise guide” on Paroxysmal Nonkinesigenic dyskinesia. Guduru Z and Sethi KD (Chapter 4). Editors: Kapil

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Sethi, Robert Erro and Kailash Bhatia. eBook ISBN: 978-3-030-53721-0. DOI: 10.1007/978-3-030-53721-0. November 2020. Springer International publishing.

XIV. RESEARCH & INTELLECTUAL CONTRIBUTIONS - continued

B. ABSTRACT PRESENTATIONS [specify type: Podium, Poster, Exhibit, Electronic, Educational Exhibit, Scientific Exhibit; oldest at top, newest at bottom in each section]

Local/State/Regional Meetings

1 10/2014 Ramanathan S; Guduru Z; Purohit A, Malhotra K; Rana S. “Acute necrotizing vasculitis mimicking glioblastoma multiformae in a patient with neuromyelitis optica.” Pennsylvania Neurological Society, Pittsburgh, PA. Poster.

2 10/2014 Ramanathan S; Guduru Z; Purohit A, Malhotra K; Rana S. “Non-convulsive status epilepticus in multiple sclerosis: two cases and review.” Pennsylvania Neurological Society, Pittsburgh, PA. Poster.

3 10/2018 Guduru Z, Gera G, Quintero J, Van Horne C, Gerhardt G. “Peripheral nerve grafts implanted into the substantia nigra in patients with

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Parkinson’s disease during deep brain stimulation surgery: 2-year follow-up study of gait parameters.” 2018 3rd annual Kentucky Neuroscience Institute (KNI) clinical-translational research symposium, Lexington, KY. Poster.

4 10/2018 Quintero JE, Guduru, Z, Gerhardt GA et al. “Validations of Apomorphine (APO)-Induced BOLD Activation Correlations in Hemi-parkinsonian Rhesus Macaques.” 2018 3rd annual Kentucky Neuroscience Institute (KNI) clinical-translational research symposium, Lexington, KY. Poster.

5 05/2019 Guduru Z, Pradeep S. “A lesson in prompt diagnosis: Ataxia with Vitamin E deficiency.” 2019 Resident Trainee Research day, University of Kentucky, Lexington, KY. Poster.

6 05/2019 Guduru Z, Ali T. “DBS programming in tremor predominant, dyskinesia predominant and rigid-akinetic predominant Parkinson’s disease.” 2019 Resident Trainee Research day, University of Kentucky, Lexington, KY. Poster.

7 05/2019 Guduru Z, Ali T. “Simple partial seizure presenting with dystonic features in acute stroke.” 2019 Resident Trainee Research day, University of Kentucky, Lexington, KY. Poster.

8 10/2020 Donigian A, Toupin D, Guduru Z. “Acquired Movement Disorders Secondary to Tumefactive Virchow Robin Spaces.” 2020 Neuroscience Clinical Translational Research Symposium, Kentucky Neuroscience Institute and UK Department of Neurology, Lexington, KY. Poster.

9 10/2020 Ali T, Guduru Z. “Rapid-Onset Dystonia Parkinsonism: Evolution of Clinical Phenotype 26 Years Post Diagnosis.” 2020 Neuroscience Clinical Translational Research Symposium, Kentucky Neuroscience Institute and UK Department of Neurology, Lexington, KY. Poster.

10 10/2020 Sekhon S, Guduru Z.  “MRI Findings in Acute Hyperammonemic Encephalopathy Secondary to Acetaminophen Toxicity.” 2020 Neuroscience Clinical Translational Research Symposium, Kentucky Neuroscience Institute and UK Department of Neurology, Lexington, KY. Poster.

11 03/2021 Kini T, Guduru Z, Sudhakar P. “Virtual didactics: survey by neurology residents at University of Kentucky” Resident Trainee Research day 2021, University of Kentucky, Lexington, KY. Podium presentation.

12 03/2021 Ali T, Guduru Z. “Caudal Zona Incerta DBS in tremor.” Resident Trainee Research day 2021, University of Kentucky, Lexington, KY. Podium presentation.

National Meetings

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1 01/2014 Ramanathan S; Guduru Z; Shaikh N; Malhotra K; Rana S. “Corpus Callosum lesion: stroke or glioblastoma?” 37th American Society of Neuroimaging, Sarasota, Florida. Poster.

2 01/2014 Ramanathan S, Malhotra K, Guduru Z, Shaikh N, Rana S. “Tumefactive Demyelination: Biopsy dilemma.” 37th American Society of Neuroimaging, Sarasota, Florida. Poster.

3 01/2014 Ramanathan S, Malhotra K, Guduru Z, Shaikh N, Rana S. “Conversion of Posterior reversible encephalopathy syndrome into irreversible cytotoxic edema and acute infarct.” 37th American Society of Neuroimaging, Sarasota, Florida. Poster.

4 01/2015 Guduru Z; Ramanathan S; Sreedhar G; Leichliter T; Rana S. “Recurrent SMART syndrome: be smart and avoid invasive testing!!” 38th American Society of Neuroimaging, Carefree, Arizona. Poster.

5 01/2015 Purohit A; Guduru Z; Dike N; Synowiec A. “Amyloid spells: diagnostic dilemma.” 38th American Society of Neuroimaging, Carefree, Arizona. Poster.

6 12/2015 Guduru Z; Agrawal D; Purohit A; Synowiec A. “LGI-1 autoimmune synaptic encephalitis: EEG as a biomarker?” 2015 American Epilepsy Society annual meeting, Philadelphia, PA. Poster.

7 01/2016 Guduru Z, Purohit A, Rana S. “TB Vasculitis and Strokes in an Immunocompetent: Rare Diagnosis becomes more rarer if not Thought.” 39th American Society of Neuroimaging, Orlando, FL. Poster.

8 01/2016 Purohit A, Guduru Z, Chaparala S, Tayal A. “Atrioesophageal Fistulas after Pulmonary Vein Isolation: a rare and deadly complication.” 39th American Society of Neuroimaging, Orlando, FL. Poster.

9 04/2016 Guduru Z, Schrmake C, Baser S, Leichliter T. “Medication Reduction After DBS Placement in Parkinson’s Disease.” 68th American Academy of Neurology, Vancouver, BC, Canada. Poster.

10 05/2016 Guduru Z. Case series of Pantothenate kinase-associated neurodegeneration (PKAN). 7th Movement Disorders Society- Pan American Society (MDS-PAS) school for young neurologists, Atlanta GA. Podium presentation.

11 02/2017 Guduru Z, Kurek J, Morgan J, Sethi K. “Bilateral facial movements following Guillain-Barre syndrome.” 1st Pan-American Parkinson’s disease and movement disorders congress, Miami, FL. Poster.

12 02/2017 Guduru Z. “Severe restless leg syndrome uncovered by Phenergan given for vomiting.” 1st Pan-American Parkinson’s disease and movement disorders congress, Miami, FL. Podium presentation. Travel award.

13 05/2017 Purohit A, Arwani M, Shah L, Nandra K, Rana S, Guduru Z. “Peripheral neuropathy as a presenting feature Creutzfeldt Jakob Disease.”

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2017 American Association of Neuromuscular & Electrodiagnostic Medicine annual meeting, Phoenix, AZ. Poster.

14 04/2018 Guduru Z, Sethi K. “Bilateral facial movements following Guillian-Barre syndrome.” 70th American Academy of Neurology (AAN) annual meeting, Los Angeles, CA. Electronic poster.

15 08/2018 Guduru Z, Baser S, Leichliter T. “Medication reduction after DBS placement in Parkinson’s disease.” Parkinson’s Study Group 29th annual meeting and 31st annual symposium, Jersey City, NJ. Poster.

16 02/2019 Van Horne C, Quintero G, Gurwell J, Guduru Z, Hines T. “Autologous Repair Cell Grafts to the Substantia Nigra Produce Clinically Important Changes that are Stable at 2 Years.” 70th Southern Neurosurgical Society Annual Meeting, Key Largo, FL. Poster.

17 02/2020 Rickard K, Guduru Z, Gera G et al. “Gait Improvements with Peripheral Nerve Graft during Deep Brain Stimulation in People with Parkinson’s Disease.” 2020 Combined Sections Meeting (CSM), Denver, CO. Poster.

18 04/2020 Vasireddy R, Khan Q, Guduru Z. "Infant presenting with Autoimmune NMDA Positive encephalitis secondary to Herpes Simplex Encephalitis: A Case Report." 72nd American Academy of Neurology (AAN) annual meeting. E-Poster.

19 04/2020 Vasireddy R, Ali T, Guduru Z. "Parkinsonism secondary to use of valbenazine and reversal with the addition of levodopa: A Case Report " 72nd American Academy of Neurology (AAN) annual meeting. E-Poster.

20 04/2020 Bates M, Chisolm J, Avasarala J, Guduru Z. "Anti-MOG and Anti-AQP4 Positive Neuromyelitis Optica Spectrum Disorder in a Patient with Myasthenia Gravis." 72nd American Academy of Neurology (AAN) annual meeting. E-Poster.

21 04/2020 Alkhasova M, Avasarala J, Sutton P, Pettigrew L, Guduru Z. “Neuromyelitis Optica Spectrum Disorders Misdiagnosed as Multiple Sclerosis: Can Current Diagnostic Guidelines Separate the Two Diseases?” 72nd American Academy of Neurology (AAN) annual meeting. E-Poster.

22 05/2020 Guduru Z, Gerhardt G, Van Horne C et al. “Seven-year review of DBS Plus: A clinical trial platform for combining delivery of investigational therapeutics with deep brain stimulation surgery in patients with Parkinson’s disease.” Parkinson’s Study Group (PSG). Poster was accepted but meeting was cancelled. PSG travel fellowship award.

23 06/2020 van Horne C, Guduru Z, Gerhardt G et al. “Seven-year review of DBS Plus: A clinical trial platform for combining delivery of investigational therapeutics with deep brain stimulation surgery in patients with Parkinson’s disease.” 2020 American Society for Stereotactic and Functional Neurosurgery. Poster was accepted but meeting was cancelled.

24 06/2020 Quintero JE, Guduru Z, van Horne CG et al. “Repair cells survive direct delivery and may provide support to substantia nigra dopaminergic neurons in a patient with Parkinson’s disease receiving

38

an investigational cell therapy.” 2020 American Society for Stereotactic and Functional Neurosurgery. Poster was accepted but meeting was cancelled.

25 09/2020 Donigian A, Toupin D, Guduru Z. “Acquired Movement Disorders Secondary to Tumefactive Virchow Robin Spaces.”  2020 American Neurological Association (ANA) virtual conference. E-Poster.

26 09/2020 Ali T, Guduru Z. Poster presentation. “Rapid-Onset Dystonia Parkinsonism: Evolution of Clinical Phenotype 26 Years Post Diagnosis.” 2020 American Neurological Association (ANA) virtual conference. E-Poster.

27 09/2020 Sekhon S, Guduru Z. “MRI Findings in Acute Hyperammonemic Encephalopathy Secondary to Acetaminophen Toxicity.” 2020 American Neurological Association (ANA) virtual conference. E-Poster.

28 04/2021 Kini T, Guduru Z, Sudhakar P. “Virtual didactics: survey by neurology residents at University of Kentucky” 73rd American Academy of Neurology virtual annual meeting. E-Poster.

29 04/2021 Ali T, Guduru Z. "Non-Ketotic Hyperglycemic Hemichorea/ Hemiballism.” 73rd American Academy of Neurology virtual annual meeting. E-Poster.

30 04/2021 Al-Janabi O, Yousuf F, Helgren L, Guduru Z. "Two Cases: of COVID-19 Encephalitis: case series" 73rd American Academy of Neurology virtual annual meeting. E-Poster.

International Meetings

1 09/2018 Guduru Z. “Two siblings with head shaking and loss of balance.” 22nd International Congress Movement Disorders Society, Hong Kong. Podium presentation. (12 cases from around the world, are selected for podium presentation per year for this podium presentation).

2 09/2018 Guduru Z, Gera G, Quintero J, Van Horne C, Gerhardt G. “Peripheral nerve grafts implanted into the substantia nigra in patients with Parkinson’s disease during deep brain stimulation surgery: 2-year follow-up study of gait parameters.” 22nd International Congress Movement Disorders Society, Hong Kong. Poster.

3 06/2019 Ginjupally D, Hines T, Guduru Z. “Ipsilateral STN and contralateral Caudal Zona incerta stimulation in patient with Tremor predominant Parkinson’s disease.” 18th Biennial Meeting of the World Society for stereotactic and functional Neurosurgery (WSSFN), New York City, NY. Poster.

4 09/2019 Guduru Z, Ali T, Ginjupally D, Van Horne C. “DBS Programming in Tremor and Akinetic-Rigid Predominant Parkinson’s Disease.” 23rd International Congress Movement Disorders Society, Nice, France. Poster.

5 09/2019 Guduru Z, Ali T, Gurwell J, Ginjupally D. “GNAO1 gene mutation: generalized dystonia without epilepsy. 23rd International Congress Movement Disorders Society, Nice, France. Poster.

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6 09/2019 Guduru Z, Ali T, Ginjupally D, Van Horne C. “Dystonic storm with a change of stimulation from constant voltage to constant current.” 23rd International Congress Movement Disorders Society, Nice, France. Poster.

7 09/2019 Ali T, Ginjupally D, Guduru Z. “Left STN DBS and right CZi DBS in a patient with Tremor-predominant Parkinson’s disease.” 23rd International Congress Movement Disorders Society, Nice, France. Poster.

8 09/2019 Ali T, Ginjupally D, Guduru Z. “Stiff limb syndrome progressing to stiff man syndrome in a non-diabetic man.” 23rd International Congress Movement Disorders Society, Nice, France. Poster.

9 09/2019 Ali T, Ginjupally D, Guduru Z. “Simple partial status epilepticus presenting with dystonic features in acute stroke.” 23rd International Congress Movement Disorders Society, Nice, France. Poster.

10 09/2019 Gera G, Guduru Z, Quintero J et al. “Improvements in gait deficits with peripheral nerve grafts implanted into the substantia nigra in patients with Parkinson’s disease during deep brain stimulation surgery: 2-year follow-up study.” 23rd International Congress Movement Disorders Society, Nice, France. Poster.

11 09/2019 Ginjupally D, Van Horne C, Guduru Z. “Evidence of survival of Peripheral nerve grafts implanted into the Substantia nigra in patients with Parkinson’s disease during deep brain stimulation surgery.” 23rd International Congress Movement Disorders Society, Nice, France. Poster.

12 09/2019 Ginjupally D, Van Horne C, Guduru Z. “Deep brain stimulation in Caudal Zona incerta: Case series.” 23rd International Congress Movement Disorders Society, Nice, France. Poster.

13 06/2020 Slevin J, Guduru Z, Van Horne C et al. “Determining the safety and feasibility of unilateral cell therapy delivery to the substantia nigra for the goal of disease modification.” XXV World Congress on Parkinson’s Disease and Related Disorders, Prague, Czech Republic. Poster.

14 09/2020 Van Horne C, Guduru Z, Gerhardt G et al. “Two-year outcome of autologous peripheral nerve grafting to the substantia nigra at the time of DBS surgery.” 24th International Congress Movement Disorders Society, virtual meeting. Poster.

15 09/2020 Quintero J, Slevin J, Guduru Z, Gurwell J, Gerhardt G, van Horne C. “Unilateral delivery of cell-based therapy to the putamen and substantia nigra in patients with Parkinson’s disease who have an existing DBS system.” 24th International Congress Movement Disorders Society, virtual meeting. Poster.

16 09/2020 Keeton G, Ali T, Sudhakar P, Guduru Z. “A case of Lance Adams Syndrome with See Saw nystagmus. 24th International Congress Movement Disorders Society, virtual meeting. Poster.

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17 09/2020 Ali T, Keeton G, Yamasaki T, Guduru Z. “Catatonia, Parkinsonism and Dystonia in a patient with Osmotic Demyelination Syndrome.” 24th International Congress Movement Disorders Society, virtual meeting. Poster.

XIV. RESEARCH & INTELLECTUAL CONTRIBUTIONS - continued

C. SPONSORED RESEARCH PROJECTS, GRANT & CONTRACT ACTIVITIES [oldest at top, newest at bottom in each section; include Pending]

Active

Project Title: DBS plus: Pilot Study to Evaluate the Safety and Feasibility of Implanting Autologous Peripheral Nerve Grafts in Subjects with Parkinson's Disease Undergoing Deep Brain Stimulation Surgery and Treatment.

Project Number: NCT#02369003Principal Investigator(s): Craig Van Horne, MDRole in Project: Sub-InvestigatorEffort: 0 %Institution/University: University of KentuckySource of Funding: ExtramuralSponsor:                                 University of Kentucky: Department of NeurosurgeryDuration of Project: 01/2018-presentTotal Award: Grant Number: Account # 1215511400.

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Project Title: P2B001: Phase 3, Twelve-week, Multi-Center, Multinational, Randomized, Double-Blind, Double-Dummy, Parallel Group Study to Determine the Efficacy, Safety and Tolerability of P2B001Once Daily Compared to its Individual Components in Subjects with Early Parkinson’s Disease and to a calibration Arm of Pramipexole ER. I have enrolled 11 patients in this trial and stood in top 10 patient recruitment centers (target was to enroll 6 patients).

Project Number:Principal Investigator(s): Zain Guduru, MDRole in Project: Principal-InvestigatorEffort: 2.5 %Institution/University: University of KentuckySource of Funding: ExtramuralSponsor name: Pharmaceutical Research AssociatesDuration of Project: 07/2018 -presentTotal Award: Received: $ 95,774. Grant Number: Account # 3048113855

Project Title: A pilot study for quantification of balance deficits in Parkinson’s disease after deep brain stimulation. UK Neurology Pilot Grant.

Project Number:Principal Investigator(s): Zain Guduru, MDRole in Project: Principal-InvestigatorEffort: 1%Institution/University: University of Kentucky: Department of NeurologySource of Funding: IntramuralDuration of Project: 02/2019 -presentTotal Award: $ 20,000Grant Number: Account # 1013173750

Project Title: A pilot study to examine apomorphine-induced BOLD activation in patients with Parkinson’s disease. CCTS (Center for clinical and translational science) Pilot grant.

Project Number:Principal Investigator(s): Zain Guduru, MDRole in Project: Principal-InvestigatorEffort: 0 %Institution/University: University of Kentucky: Center for clinical and translational science. Source of Funding: IntramuralDuration of Project: 07/2019 -presentTotal Award: 46,000$Grant Number: Account # 1013178070

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Project Title Trial Of Parkinson's And Zoledronic Acid (TOPAZ)Project NumberPrincipal Investigator(s) John Slevin, MD Role in Project Co-Investigator Effort:  0Institution/University University of Kentucky Source of Funding ExtramuralSponsor Parkinsons FoundationDuration of Project 04/20-06/22Total Award:  $ 0Grant number: 3200003558

Project Title: Characterization of a specialty Normal pressure Hydrocephalus (NPH) clinic. The purpose of this study is to collect a systematic, standardized, standard-of-care database on patients suspected of having NPH at the UK Kentucky Neuroscience Institute (KNI) Clinic.

Project Number: IRB number: 44619, University of Kentucky.Principal Investigator(s): Charles Smith, MDRole in Project: Sub-InvestigatorEffort: 0 %Institution/University: University of KentuckySource of Funding: IntramuralSponsor:                                 University of Kentucky: Department of Neurology. Duration of Project: 07/2020 -presentTotal Award: Grant Number: Account # None (PI Funded).

Project Title: RAD-PD: Registry for the advancement of Deep Brain Stimulation in Parkinson’s.

Project Number:Principal Investigator(s): Zain Guduru, MDRole in Project: Principal-InvestigatorEffort: 2.5%Institution/University: University of KentuckySource of Funding: ExtramuralSponsor Name:      Neuropoint Alliance Incorporated. Duration of Project: 01/2021-presentTotal Award: Budget of $20,100. Grant Number: Account # 3048114993.

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Project Title: Molecular and functional biomarkers of Parkinson’s disease (Quadrant Biosciences).

Project Number:Principal Investigator(s): Zain Guduru, MDRole in Project: Principal-InvestigatorEffort: 5%Institution/University: University of KentuckySource of Funding: ExtramuralSponsor Name:      Quadrant Biosciences Incorporated. Duration of Project: 03/2021 -presentTotal Award: Budget of $436,282. Grant Number: Account # 3048114927.

Project Title: CVL-751-PD-001. A phase 3, double-blind, randomized, placebo-controlled, parallel-group, 27-week trial to evaluate the efficacy, safety and tolerability of two fixed doses of tavapadon in early Parkinson’s disease (tempo – 1 trial).

Project Number:Principal Investigator(s): Zain Guduru, MDRole in Project: Principal-InvestigatorEffort: 1%Institution/University: University of KentuckySource of Funding: ExtramuralSponsor Name: Syneos Health LLCDuration of Project: 03/2021-presentTotal Award: Budget of $150,240; Received: $9,431Grant Number: Account # 3048114762

Project Title: CVL-751-PD-003. A phase 3, double-blind, randomized, placebo-controlled, parallel-group, flexible- dose, 27-week trial to evaluate the efficacy, safety, and tolerability of tavapadon as adjunctive therapy for Parkinson’s disease in levodopa-treated adults with motor fluctuations (tempo-3 trial).

Project Number:Principal Investigator(s): Zain Guduru, MDRole in Project: Principal-InvestigatorEffort: 2.5%Institution/University: University of KentuckySource of Funding: ExtramuralDuration of Project: 03/2021 -presentTotal Award: Budget of $126,095Grant Number: Account # Pending UK Account Number.

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Project Title: CVL-751-PD-004. 58-week open-label trial of tavapadon in parkinson’s disease (tempo-4 trial). Pending regulatory documents and IRB approval.

Project Number:Principal Investigator(s): Zain Guduru, MDRole in Project: Principal-InvestigatorEffort: 2%Institution/University: University of KentuckySource of Funding: ExtramuralDuration of Project: 03/2021 -presentTotal Award: Budget of $86,009; Received: $0Grant Number: Account # 3048115051

Inactive

Project Title A Phase 3, Multicenter, Randomized, Double-Blind, Placebo- Controlled Study with an Open-Label Phase to Determine the Efficacy and Safety of Tozadenant as Adjunctive Therapy in Levodopa-Treated Patients with Parkinson’s Disease Experiencing End-of-Dose “Wearing-Off” (TOZ-PD).

Project Number Biotie TOZ-CL05Principal Investigator(s) John Morgan, MD Role in Project Sub-Investigator Effort:  0%Institution/University Augusta UniversitySource of Funding ExtramuralSponsor Biotie TherapiesDuration of Project 8/25/15-5/16/18Total Award:  7 subjects enrolledGrant number: N/A Clinical trial

Project Title An Open-Label, Phase 3 Study Examining the Long-Term Safety, Tolerability and Efficacy of APL-130277 in Levodopa Responsive Patients with Parkinson’s Disease Complicated by Motor Fluctuations (“OFF” Episodes).

Project NumberPrincipal Investigator(s) John Morgan, MD Role in Project Sub-Investigator Effort:  0%Institution/University Augusta UniversitySource of Funding ExtramuralSponsor Cynapsus Therapeutics IncDuration of Project 10/7/15-8/25/16Total Award:  0 subjects enrolledGrant number: N/A Clinical trial

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Project Title DUOGLOBE: Duodopa/duopa in patients with advanced Parkinson’s disease a global observation study evaluating long term effectiveness.

Project Number NCT02611713Principal Investigator(s) John Slevin, MD Role in Project Sub-Investigator Effort:  0%Institution/University University of Kentucky Source of Funding ExtramuralSponsor AbbVie IncorporatedDuration of Project 02/2016-02/2018Total Award:  $5,500Grant number: 3048113030

Project Title A Phase 3, Open-Label Study of the Safety, Efficacy, and Tolerability of Apomorphine Administered by Continuous Subcutaneous Infusion in Advanced Parkinson’s Disease Patients with Unsatisfactory Control on Available Therapy.

Project Number USWM-AP2-3000Principal Investigator(s) Kapil Sethi, MD Role in Project Sub-Investigator Effort:  0%Institution/University Augusta UniversitySource of Funding ExtramuralSponsor US WorldMeds, LLCDuration of Project  6/21/16-7/25/18Total Award:  2 subjects enrolledGrant number: N/A Clinical trial

Project Title A multicenter, international, open-label, safety study of ND0612, a solution of levodopa/carbidopa delivered via a pump system as a continuous subcutaneous infusion in subjects with advanced Parkinson's Disease (UBeyoNDU).

Project Number UBeyoNDU ND0612H-012Principal Investigator(s) John Morgan, MD Role in Project Sub-Investigator Effort:  0%Institution/University Augusta UniversitySource of Funding ExtramuralSponsor NeuroDerm Ltd.Duration of Project 3/24/17 -5/3/18Total Award:  0 subjects enrolled

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Grant number: N/A Clinical trial

Project Title M15-562: A Randomized, Double-Blind, Placebo-Controlled Multiple Dose Study to Assess Efficacy, Safety, Tolerability, and Pharmacokinetics of ABBV-8E12 in Progressive Supranuclear Palsy.

Project Number NCT02985879Principal Investigator(s) John Slevin, MD Role in Project Sub-Investigator Effort:  2.5 %Institution/University University of Kentucky Source of Funding ExtramuralSponsor AbbVie Incorporated.Duration of Project 04/2017-10/2020Total Award:  $390,271Grant number: 3048113480

Project Title STEADY PD III: A Phase 3 double-blind placebo-controlled parallel group study of isradipine as a disease modifying agent in subjects with early Parkinson disease.

Project Number NCT02168842Principal Investigator(s) John Slevin, MD Role in Project Sub-Investigator Effort:  1%Institution/University University of Kentucky Source of Funding ExtramuralSponsor Northwestern UniversityDuration of Project 04/2017-03/2018Total Award:  $30,662Grant number: 3200001328

Project Title CTH-301: An Open-Label, Phase 3 Study Examining the Long-Term Safety, Tolerability and Efficacy of APL-130277 in Levodopa Responsive Patients with Parkinson#s Disease Complicated by Motor Fluctuations (#OFF# Episodes)

Project Number NCT02542696Principal Investigator(s) John Slevin, MD Role in Project Sub-Investigator Effort:  1.5%Institution/University University of Kentucky Source of Funding Extramural

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Sponsor Sunovion Pharmaceuticals IncorporatedDuration of Project 05/2017-01/2021Total Award:  $85,760Grant number: 3048113525

Project Title An Open-Label, Phase 3 Study Examining the Long-Term Safety, Tolerability and Efficacy of APL-130277 in Levodopa Responsive Patients with Parkinson’s Disease Complication by Motor Fluctuations (“OFF” Episodes).

Project Number NCT02542696 Principal Investigator(s) John Slevin, MD Role in Project Co-Investigator Effort:  1%Institution/University University of Kentucky Source of Funding ExtramuralSponsor Sunovion PharmaceuticalsDuration of Project 05/2017-07/2018Total Award:  $ 31,051Grant number: 3048113526

Project Title A Randomized, Double-Blind, Placebo-Controlled Multiple Dose Study to Assess Efficacy, Safety, Tolerability, and Pharmacokinetics of ABBV-8E12 in Progressive Supranuclear Palsy.

Project Number M15-562 PSPPrincipal Investigator(s) John Morgan, MD Role in Project Sub-Investigator Effort:  0%Institution/University Augusta UniversitySource of Funding ExtramuralSponsor AbbVie Incorporated.Duration of Project 6/14/17-8/24/20Total Award:  3 subjects enrolledGrant number: N/A Clinical trial

Project Title TOZ-CL06: A Multicenter, Open-Label Study to Evaluate the Safety and Tolerability of Tozadenant as Adjunctive Therapy in Levodopa-Treated Patients with Parkinson’s Disease Experiencing End of Dose “Wearing-Off”.

Project Number NCT03051607Principal Investigator(s) John Slevin, MD Role in Project Sub-Investigator Effort:  0.5%

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Institution/University University of Kentucky Source of Funding ExtramuralSponsor Biotie Therapeutics IncorporatedDuration of Project 5/12/2017 to 4/2/2018Total Award:  $9,002Grant number: 3048113551

Project Title NILO-PD study: Safety and tolerability of daily oral administration of nilotinib (150-300mg once daily) in Parkinson's Disease.

Project Number NCT03205488Principal Investigator(s) John Slevin, MD Role in Project Sub-Investigator Effort:  0.5%Institution/University University of Kentucky Source of Funding ExtramuralSponsor Northwestern UniversityDuration of Project 11/7/2017 to 9/17/2019Total Award:  $5,540Grant number: 3048113744

Project Title M15-739: An open label study in subjects with Parkinson’s disease to evaluate the safety and tolerability of titration and continuous subcutaneous infusion of ABBV-951 for up to 4 weeks in an outpatient environment.

Project Number NCT03374917Principal Investigator(s) John Slevin, MD Role in Project Sub-Investigator Effort:  1.5%Institution/University University of Kentucky Source of Funding ExtramuralSponsor AbbVie IncorporatedDuration of Project 2/28/2018 to 1/6/2020Total Award:  $46,513Grant number: 3048113815

Project Title M15-563: Phase 2 extension of Study M15-562 to assess the long-term safety, tolerability and efficacy of ABBV-8E12 in subjects with progressive supranuclear palsy.

Project Number NCT03391765Principal Investigator(s) John Slevin, MD Role in Project Sub-Investigator Effort:  2.5%

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Institution/University University of Kentucky Source of Funding ExtramuralSponsor AbbVie IncorporatedDuration of Project 03/2018-06/2020Total Award:  $254,030Grant number: 3048113829

Project Title M15-738: A Single Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of 24- and 74-Hour Subcutaneous Infusions of ABBV-951 in Subjects with Parkinson’s Disease.

Project Number NCT03033498Principal Investigator(s) John Slevin, MD Role in Project Sub-Investigator Effort:  1.5%Institution/University University of Kentucky Source of Funding ExtramuralSponsor AbbVie IncorporatedDuration of Project 3/13/2018 to 3/5/2020Total Award:  $74,714Grant number: 3048113840

Project Title M15-741: A 52-Week, Open-label, Single-arm Study to Evaluate the Safety and Tolerability of 24-hour Daily Exposure of Continuous Subcutaneous Infusion of ABBV-951 in Subjects with Parkinson's Disease.

Project Number NCT04379050Principal Investigator(s) John Slevin, MD Role in Project Sub-Investigator Effort:  1 %Institution/University University of Kentucky Source of Funding ExtramuralSponsor AbbVie IncorporatedDuration of Project 5/1/2019 to 6/14/2021Total Award:  $35,120Grant number: 3048114491

Project Title ND0612-317: A multicenter, randomized, active-controlled, double-blind, double-dummy, parallel group clinical trial, investigating the efficacy, safety, and tolerability of continuous subcutaneous ND0612 infusion in comparison to oral IR-LD/CD in subjects with Parkinson’s disease experiencing motor fluctuations (BouNDless).

Project Number NCT04006210

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Principal Investigator(s) John Slevin, MD Role in Project Sub-Investigator Effort:  0 %Institution/University University of Kentucky Source of Funding ExtramuralSponsor Syneos Health LLCDuration of Project 12/3/2019 to 12/11/2020Total Award:  $ 0Grant number: 3048114599

XV. OTHER ACTIVITIES

1. 05/2018: Contributed to the Neurology Grand rounds Jeopardy at University of Kentucky.

2. 05/2018: Developed CPX tremor case for UK College of Medicine for third year medical students.

3. 08/2020: SNMA medical student conference: guided African or African American students for neurology residency. Organized by University of Kentucky.

4. 10/2020: National Hispanic Medical Association (NHMA) council of residents faculty webinar: guided Hispanic medical students for neurology residency.

5. 11/2020: Sharing our innovative 4:1 resident schedule with Residency Program Director, University of Oklahoma.

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