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M.R. Abbaszadegan Page 1 of 26
CURRICULUM VITAE
MOHAMMAD R. ABBASZADEGAN, MT (ASCP), Ph.D.
Professor
Head, Medical Genetic Research Center (MGRC), School of Medicine,
Mashhad University of Medical Sciences
&
Director, Division of Human Genetics
Avicenna Research Institute
&
Adjunct Faculty at the Arizona State University & George Mason University
Address: Division of Human Genetics, Avicenna Research Institute
Mashhad University of Medical Sciences
Ferdosi Square, Bu-Ali Sq., Mashhad, Khorasan, Iran Postal Code: 9196773117
(98-511) 7112343, Fax: (98-511) 7112343, Email: [email protected]
CERTIFICATION
Medical Geneticist: American Board of Medical Genetics, Board Eligible
Clinical Molecular Geneticist, National Human Genome Research Institute, NIH
Medical Technologist: American Society of Clinical Pathologist (ASCP)
Medical Laboratory Scientist: National Certifying Agency (NCA)
EDUCATION
8/90-5/95 Ph.D. in Pharmacology & Toxicology – Cancer Genetics
University of Arizona Medical Center, Tucson, Arizona 85721
Minor: Microbiology & Immunology
Major Advisor: William S. Dalton, M.D., Ph.D.
Dissertation: Molecular Mechanisms of Drug Resistance in Human Malignancies.
1/87-12/90 Master of Science in Applied Microbiology
Northern Arizona University, Flagstaff, Arizona 86011
Major Advisor: Emmanuel T. Akporiaye, Ph.D.
Thesis: Tumoricidal Activity of Tumor Infiltrating T-lymphocytes Against EMT6
(mammary carcinoma) Tumor Cells, Following the Injection of Viable or Irradiated
Tumor Cells
9/81-6/85 Bachelor of Science in Microbiology
University of Montana, Missoula, Montana 59801
PROFESSIONAL EXPERIENCE
M.R. Abbaszadegan Page 2 of 26
8/09-7/10 Adjunct Faculty at TGen and The Arizona State University (Sabbatical), The Translational
Genomics Research Institute (TGen), Phoenix, AZ 85004, Director: Jeff Trent, Ph.D.
7/03- 10/03 Fellowship –Diagnosis of Rare Genetic Diseases & their Prenatal Genetic Diagnosis,
GeneDx, Inc. DNA Diagnostic Institute affiliated with NIH, Director: Sherri Bale, Ph.D.,
FABCG.
1/98- 1/2000 Fellowship – Clinical Molecular Genetics, The American Board of Medical Genetics
NIH/ Georgetown / Children’s Medical Center Joint fellowship program
Program Director: Clair A. Francomano, M.D.
6/95- 11/97 Postdoctoral Fellow-Intramural Research Training Award (IRTA)
Diagnostic Development Branch
National Human Genome Research Institute, NIH, Bethesda, Maryland 20892
Advisor: Mark R. Hughes, M.D., Ph.D.
Project: Research and Development of new diagnostic assays for human genetic
diseases, Prenatal genetic diagnosis & Familial Breast Cancer
7/85-8/86 Medical Technology Internship Program
Bannock Regional Medical Center, Pocatello, Idaho 83204
Certificates: American Society of Clinical Pathologist (ASCP) & National Certifying
Agency (NCA)
RELEVANT WORK EXPERIENCE
8/2000-Now Assistant, Associate and now Professor, Medical Genetics
Head, Medical Genetics Research Center
Mashhad University of Medical Sciences
Mashhad, Iran
11/96- 8/98 Assistant Professor
Institute for Molecular & Human Genetics
Georgetown University Medical Center
3800 Reservoir Road, 4 Main, M4000
Washingtion D.C. 20007
6/95- 11/96 Postdoctoral Fellow
Diagnostic Development Branch
National Center for Human Genome Research, NIH, Bethesda, Maryland 20892
Principal investigator: Mark R. Hughes, M.D., Ph.D.
Project: Research and Development of new diagnostic assays for human
genetic diseases, Prenatal & Preimplantation genetic diagnosis & Familial
Breast Cancer
1/90-8/90 Research Assistant II
University of Arizona Medical Center, Tucson, Arizona 85721
Internal Medicine/Gastroenterology
Principal investigator: David Earnest, M.D.
M.R. Abbaszadegan Page 3 of 26
Project: Studying the mechanism of vitamin A potentiation of xenobiotic hepatotoxicity;
vitamin A activation of Kupffer cells in vitro and in vivo.
6/88-3/89 Medical Technologist
Public Health Service Indian Hospital, Tuba City, Arizona 86045 Laboratory Services
Laboratory Manager: Bruce Gardner
TEACHING EXPERIENCES
Courses taught:
Medical Genetics, Genetic Counseling Training Courses, Molecular and Cellular Biology, NIH training
courses for summer students and fellows, Laboratory Sciences, Immunobiology, General Biology, and
Bacteriology
AWARDS
6/1988 Sigma Xi, the Scientific Research Society
6/1995 National Institute of Health Intramural Research Training Award (IRTA)
3/1996 NIH Fellows Award for Research Excellence
12/2005 Khwarizmi First Award for Applied Medical Protocols (Congenital Adrenal Hyperplasia)
2013 3rd rank of the 19th Razi research festival on medical sciences
PROFESSIONAL SOCIETIES
American Society of Human Genetics
American Association for the Advancement of Science
Associate Member, American Association for Cancer Research
Student/Fellow Member, American Society for Microbiology
American Society of Medical Technologists
The Academy of Medical Sciences, I.R. of IRAN
SERVICE ACTIVITIES
Reviewer for the following Peer-Reviewed Journals:
World Journal of Gastroenterology, International Journal of Cancer, Archives of Iranian Medicine,
Eastern Mediterranean Health Journal, Genetic Testing, Iranian Journal of Public Health, Journal of
Research in Medical Sciences, Tumor Biology
Cancer therapeutics:
Preparation of DC-mRNA vaccine for treatment of Esophageal Squamous Cell Carcinoma (ESCC)
patients, DC-mRNA vaccine against gastric cancer stem cells, shRNA against MAML1, a notch
transactivation factor, master switch.
Biotechnology:
Designing, production and evalution of HTLVI, II diagnostic kit for detection of antibody against
HTLV virus, using HTLV recombinant Envelope proteins
Consulting for the following Institutions:
M.R. Abbaszadegan Page 4 of 26
Georgetown University Medical Center, Washington D.C.
GeneDx Inc., Gaithersburg, MD
Panacea Inc., Gaithersburg, MD
InnodevTech Inc., Phoenix, AZ
Metrics Instruments Inc., Phoenix, AZ
Civil, Environmental & Sustainable Engineering, Arizona State University, Tempe, AZ
GRANTS & Licensing a Technology
Primary Investigator:
1/15-7/17 MUMS research council and Presidential research award, Isolation of Gastric Cancer
stem cells (CSC) and preparation of DC-cell therapy using CSC mRNA.
6/14-6/16 MUMS research council, Isolation of ESCC Cancer stem cells and treating with
shRNA against MAML1, a notch signaling pathway master transactivator.
5/12-5/14 World Health Organization, EMGEN. Designing Conditional Sleeping Beauty
Transposition System for Modeling Esophageal Squamous Cell Carcinoma in Mouse
2/12-2/14 World Health Organization, EMGEN. Role of MAML1 in esophageal squamous
cell carcinoma cell biology
01/11-10/12 Mashhad University of Medical Sciences (MUMS) research council Joint Grant
Approval; Chimeric super-antigen synthesis for preparation of immunogenetherapy of Esophageal
Squamous Cell Carcinoma (ESCC) patients.
2/07-02/11 Digestive Disease Research Center, Tehran University of Medical Sciences (TUMS)
& Mashhad University of Medical Sciences (MUMS) research council Joint Grant Approval;
Preparation of DC-mRNA vaccine for treatment of Esophageal Squamous Cell Carcinoma (ESCC)
patients.
8/08-11/09 MUMS research council Grant; Evaluation of GST1 polymorphisms as biomarkers in
screening of ESCC.
5/06-6/08 MUMS research council Grant; Evaluation of Long DNA and BAT-26 Markers in
detection of colorectal cancer (CRC) by molecular analysis of patient's stool DNA in comparison with
normal subjects.
7/03-9/06 MUMS research council Grant; Molecular Analysis of CYP21A2 gene in 21-
hydroxylase deficiency and CYP11B in 11-hydroxylase deficiency in congenital adrenal hyperplasia
patients.
2/04-3/05 MUMS research council Grant; Mutation detection of TCIRG1 Gene in patients with
osteopetrosis.
4/00-5/04 National Medical Biotechnology Network Grant, Ministry of Health & Public
Services; Designing, production and evalution of HTLVI, II diagnostic kit for detection of antibody
against HTLV virus using HTLV recombinant Envelope proteins.
6/97-7/99 Department of Defense, Army Breast Cancer Grant - A case controlled study of
somatic changes in primary breast tumors from BRCA1 & BRCA2 mutation carriers compared to
sporadic breast tumors.
5/97-7/98 Transfer of technology “5’ Nuclease Allelic Discrimination Assay” - License
Agreement between Institute for Molecular & Human Genetics, Georgetown University Medical
Center and Institute of Medical Molecular Genetics, Berlin, Germany.
Co-Investigator:
M.R. Abbaszadegan Page 5 of 26
10/96-10/98 National Institute of Health, Screening for mutations in Breast and Ovarian Cancer
Susceptibility Genes, BRCA1 and BRCA2, in high risk families and psyco-social behavioral aspects of
this genetic testing (C. Lerman, P.I.).
6/97-7/99 Department of Defense, Army Breast Cancer Grant - Study of chromosomal
imbalances in microdissected breast tumor cells from a heterogenous population of cells derived from a
breast tumor section (B. Haddad, P.I.).
Research Projects in Iran*
*The projects that funding not specified was all approved by MUMS research council
Division of Human Genetic, Immunology Research Center, MUMS
Cancer Genetics:
1. Preparation of DC-mRNA vaccine for treatment of Esophageal Squamous Cell Carcinoma
(ESCC) patients (Joint Approval by Digestive Disease Research Center, Tehran University of
Medical Sciences & MUMS research council).
2. Evaluation of exfoliative cytology and new serum biomarkers in screening of ESCC (Approved
by national medical research council).
3. Evaluation of GST1 polymorphisms as biomarkers in screening of ESCC.
4. Evaluation of Long DNA and BAT-26 Markers in detection of colorectal cancer (CRC) by
molecular analysis of patient's stool DNA in comparison with normal subjects.
5. Evaluation of frequency of changes in P14 & P16 genes in CRC patients.
6. Prognostic Significance of Germ-line E-Cadherin Mutation in Familial Gastric Cancer.
7. Molecular analysis of Wnt signaling pathway in Gastric cancer.
8. Microsatellite analysis in CRC patients.
9. Study of the association of HPV infection and P53 mutation with ESCC.
10. Microsatellite markers analysis in endometrial & ovarian cancer.
11. Assessment of P53 mutation in pathological staging and surgical margins in squamous cell
carcinoma of the head and neck.
Medical Genetics:
1. Molecular Analysis of CYP21A2 gene in 21-hydroxylase deficiency and CYP11B in 11-
hydroxylase deficiency in congenital adrenal hyperplasia patients in Iran.
2. Friedreich Ataxia: Molecular detection of FRDA GAA repeats in proband from a family in
province of Khorasan.
3. Preimplantation Genetics Diagnosis of - thalassemia using single cell PCR techniques.
4. Carrier detection and prenatal diagnosis of Hemophilia A and Finding of their Common mutation
by Molecular Genetics in Khorasan province
5. Mutation detection of TCIRG1 Gene in patients with osteopetrosis by PCR & RT-PCR.
M.R. Abbaszadegan Page 6 of 26
6. Evaluation of HTLV-I tax polymorphism as a probable risk factor for HAM/TSP in Khorasanian
patients.
Biotechnology:
1. Designing, production and evalution of HTLVI, II diagnostic kit for detection of antibody against
HTLV virus using HTLV recombinant Envelope proteins.
Funded by National Medical Biotechnology Network
***************************************
GenBank new sequence submissions:
1. Homo sapiens perforin gene, intron 1 (AY489286.1)
2. Human T-lymphotropic virus 1 isolate MTA-1 from Iran truncated envelope glycoprotein gene, partial
cds (DQ911752.1)
3. Homo sapiens isolate patient 1 steroid 21-hydroxylase (CYP21A2) gene, exons 9, 10 and partial cds.
(EU236681)
4. Homo sapiens isolate patient 2 steroid 21-hydroxylase (CYP21A2) gene, exons 9, 10 and partial cds.
(EU236682)
5. Homo sapiens mitochondrial 11beta-hydroxylase (CYP11B1) gene, exons 7, 8 and partial cds; nuclear
gene for mitochondrial product.(EU236683)
6. Homo sapiens adenomatous polyposis coli gene, partial cds. (EU681189)
7. Homo sapiens beta-catenin gene, partial cds.(EU681190)
8. Homo sapiens adenomatous polyposis coli gene, partial cds. (EU681276)
9. Homo sapiens beta-catenin gene, partial cds. (EU681277)
10. Tetraogallus caspius isolate CS1 cytochrome b (cytb) gene, partial cds; mitochondrial.(EU106676)
11. Homo sapiens potassium channel inwardly rectifing subfamily J member 11 (KCNJ11) gene, complete
cds (GU170814.1).
12. Homo sapiens truncated mitochondrial cytochrome P450 11B1 (CYP11B1) gene, exon 2 and partial cds;
nuclear gene for mitochondrial product (GU201906.1)
BOOKS
Tafazoli AR, Abbaszadegan MR. Next Generation Sequencing Technologies in Medical
Genetics, C. Alexander Valencia, et al. Translated to Farsi, 2017.
Abbaszadegan MR, Ghazaee S, Keify F, Mirzaee F. Clinical Cytogenetics: Classical, Molecular
advances. (Farsi), 2012.
Abbaszadegan MR, Gholamin M, Invited Book Chapter: Human T-Cell Lymphotropic Virus
(HTLV-1) and Adult T-Cell Leukemia. Editors: Babusikova O, Dovat S, Payne KJ,: T-Cell
Leukemia (chapter2), October 2011.
M.R. Abbaszadegan Page 7 of 26
Abbaszadegan MR, Ghayour M: Genetic and Nutrition Chapter, Harrison’s Principle of Internal
Medicine, 16th Edition, Supervisors in Translation to Farsi, 2006
Ghazvini K, Rezaee AR, Mohammadian-Roshan G, Rezaee-Talab GH, Abbaszadegan MR:
Diagnostic Virology (Farsi), 2008
PUBLICATIONS Articles
Ardalan Khales, S., Abbaszadegan, M.R., Majd, A., Forghanifard, M. M. Linkage between EMT
and stemness state through molecular association between TWIST1 and NY-ESO1 in esophageal
squamous cell carcinoma. BiochimieVolume 163, August 2019, Pages 84-93
Moghbeli, M., Mosannen Mozaffari, H., Memar, B., Gholamin, M., Abbaszadegan, M.R. Role of
MAML1 in targeted therapy against the esophageal cancer stem cells. Journal of Translational
Medicine. Volume 17, Issue 1, 16 April 2019, Article number 126
Tafazoli, A., Behjati, F., Farhud, D.D., Abbaszadegan, M.R. Combination of genetics and
nanotechnology for down syndrome modification: A potential hypothesis and review of the
literature. Iranian Journal of Public Health.Volume 48, Issue 3, 12 March 2019, Pages 371-378
Shariat Razavi, S.M., Forghanifard, M.M., Kordi-Tamandani, D.M., Abbaszadegan, M.R.
MAML1 regulates EMT markers expression through NOTCH-independent pathway in breast
cancer cell line MCF7. Biochemical and Biophysical Research Communications
510(3), pp. 376-382
Bagheri, V., Abbaszadegan, M.R., Memar, B., Mahmoudian, R.A., Gholamin, M. Induction of T
cell-mediated immune response by dendritic cells pulsed with mRNA of sphere-forming cells
isolated from patients with gastric cancer. Life SciencesVolume 219, 15 February 2019, Pages 136-
143
Keyfi, F., Abbaszadegan, M.R., Sankian, M., Alijanpour, M., Varasteh, A. Mutation analysis of
genes related to methylmalonic acidemia: identification of eight novel mutations. Molecular
Biology ReportsVolume 46, Issue 1, 1 February 2019, Pages 271-285
Ghaemi, N., Ghahraman, M., Noroozi Asl, S., (...), Moghbeli, M., Abbaszadegan, M.R. Novel
DNA variation of GPR54 gene in familial central precocious puberty. Italian Journal of Pediatrics.
Volume 45, Issue 1, 11 January 2019, Article number 10
Moghbeli, M., Makhdoumi, Y., Soltani Delgosha, M., Abdollahi, A., Abbaszadegan, M.R.
ErbB1 and ErbB3 co-over expression as a prognostic factor in gastric cancer. Biological
research.Volume 52, Issue 1, 8 January 2019, Page 2
Forghanifard, M.M., Abbaszadegan, M.R., Moghbeli, M. Role of SIZN1 in esophageal squamous
cell carcinoma. Middle East Journal of Cancer, Volume 10, Issue 1, 1 January 2019, Pages 37-42
M.R. Abbaszadegan Page 8 of 26
Forghanifard, M.M., Naeimi Khorasanizadeh, P., Abbaszadegan, M.R., Javdani Mallak,
A., Moghbeli, M. Role of DIDO1 in Progression of Esophageal Squamous Cell Carcinoma. Journal
of Gastrointestinal Cancer2019
Golyan, F.F., Moghaddassian, M., Forghanifard, M.M., Mahmoudian, R.A., Abbaszadegan, M.R.
Whole Exome Sequencing Reveals a Novel Damaging Mutation in Human Fibroblast Activation
Protein in a Family with Esophageal Squamous Cell Carcinoma. Journal of Gastrointestinal
Cancer2019
Khorasani, Z.M., Bagheri, R.K., Yaghoubi, M.A., (...), Abbaszadegan, M.R., Sahebkar, A.
The association between serum irisin levels and cardiovascular disease in diabetic patients.
Diabetes and Metabolic Syndrome: Clinical Research and Reviews Volume 13, Issue 1,
January - February 2019, Pages 786-790
Vojdani, S., Milanizadeh, S., Molaei, F., (...), Talee, M.R., Abbaszadegan, M.R. Mutation
Screening of KCNQ1 and KCNE1 Genes in Iranian Patients With Jervell and Lange-Nielsen
Syndrome. Fetal and Pediatric Pathology 2019
Abbaszadegan, M.R., Moghbeli, M .Genetic and molecular origins of colorectal Cancer
among the Iranians: Diagnostic Pathology. Volume 13, Issue 1, 22 December 2018, Article
number 97. e
Keyfi, F.a,b,Ebrahimzadeh-Vesal, R.d,Zhiyan, N.b,e, Nayebi, M.f,Nasseri, M.b,
Abbaszadegan, M.R.,c. The relationship between MTHFR polymorphisms and abortion in
Iranian women. Gene ReportsVolume 13, December 2018, Pages 130-133
Khorashad, B.S.aRoshan, G.M.a, Reid, A.G.b,Aghili, Z.a,Moghadam, M.D.c,Khazai,
B.a,Hiradfar, M.d,Afkhamizadeh, M.e,Ghaemi, N.c,Talaei, A.a,Abbaszadegan, M.R.f
,Aarabi, A.f,Dastmalchi, S.g,Van de Grift, T.C.h,i, Childhood Sex-Typed Behavior and
Gender Change in Individuals with 46,XY and 46,XX Disorders of Sex Development: An
Iranian Multicenter Study(Article) Archives of Sexual Behavior, Volume 47, Issue 8, 1
November 2018, Pages 2287-229
Kassner, U.fb, Klose, G.fc, König, C.fd, König, W.ez, Otte, B.fe, Parhofer, K.ff, Schatz,
U.fa, Schmidt, N.ev, Steinhagen-Thiessen, E.fb, Vogt, A.ff, Antza, C.fi, Athyros, V.fi, Bilianou,
E.fj, Boufidou, A.fk, Chrousos, G.fl, Elisaf, M.fg, Garoufi, A.fm, Katsiki, N.fn, Kolovou,
G.fo, Kotsis, V.fi, Rallidis, L.fp, Rizos, C.fg, Skalidis, E.fq, Skoumas, I.fr, Tziomalos, K.fs,
Shawney, J.P.S.fw, Abbaszadegan, M.R.a, Overview of the current status of familial
hypercholesterolaemia care in over 60 countries - The EAS Familial Hypercholesterolaemia Studies
Collaboration (FHSC) AtherosclerosisVolume 277, 10 October 2018, Pages 234-255
Abbaszadegan, M.R.a,Riahi signaling pathways as activators for epidermal growth factor receptor
in esophageal squamous cell carcinoma, A.b,Forghanifard, M.M.c,Moghbeli, M.d WNT and
NOTCH . Cellular and Molecular Biology LettersOpen AccessVolume 23, Issue 1, 3 September
2018, Article number 42
M.R. Abbaszadegan Page 9 of 26
Motamedi Rad, N.a,Rezaeishahmirzadi, M.b, Shakeri, S.b, Abbaszadegan, M.Rc, Shekari, M.d
Association of IL-1B+3954 and IL-1RN polymorphisms in chronic gastritis and peptic
ulcer(Article)Iranian Journal of Public HealthOpen AccessVolume 47, Issue 9, 1 September 2018,
Pages 1363-1369
Abbaszadegan, M.R,b,Taghehchian, N.,br,Li, L.c,Aarabi, A.a, Moghbeli, M.d Contribution of
KCTD12 to esophageal squamous cell carcinoma(Article)(Open Access) BMC Cancer, Volume 18,
Issue 1, 29 August 2018, Article number 853
Abbaszadegan, M.R.a,b,Taghehchian, N.a,Aarabi, A.b,Moghbeli, M.cMAEL Cancer-
Testis Antigen as a Diagnostic Marker in Primary Stages of Gastric Cancer with
Helicobacter pylori Infection. Journal of Gastrointestinal Cancer,2018.
Khaleghizadeh M, Forghanifard MM, Rad A, Farshchian M, Hejazi Z, Gholamin M, Memar
B , Abbaszadegan MR. “Ectopic Expression of Human DPPA2 Gene in ESCC Cell Line
Using Retroviral System”. Avicenna journal of medical biotechnology 10, no. 2 (2018):75.
Bitaraf SM, Mahmoudian RA, Abbaszadegan MR, Mohseni Meybodi A, Taghehchian N,
Mansouri A, Forghanifard MM, Memar B, Gholamin M. “Association of Two CD44
Polymorphisms with Clinical Outcomes of Gastric Cancer Patients”. Asian Pacific Journal
of Cancer Prevention 19, no. 5 (2018):1313-8.
Molaei F, Forghanifard MM, Fahim Y, Abbaszadegan MR. “Molecular Signaling in
Tumorigenesis of Gastric Cancer”. Iranian biomedical journal 22, no.4 (2018):217-30.
Bagheri V, Memar B, Momtazi AA, Sahebkar A, Gholamin M, Abbaszadegan MR.
“Cytokine networks and their association with Helicobacter pylori infection in gastric
carcinoma”. Journal of cellular physiology 233, no.4 (2018): 2791-803.
Bagheri V, Memar B, Behzadi R, Aliakbarian M, Jangjoo A, Bahar MM, Talebi S, Gholamin M,
Abbaszadegan MR. “Isolation and identification of chemotherapy‐enriched sphere‐forming cells
from a patient with gastric cancer”. Journal of cellular physiology. Journal of Cellular Physiology
233(10), pp. 7036-7046
Farshchian M, Matin MM, Armant O, Geerts D, Dastpak M, Nakhaei-Rad S, Tajeran M,
Jebelli A, Shahriyari M, Bahrami M, Fallah A, Yaghoobi V, Mirahmadi M, Abbaszadegan
MR, Bahrami AR. “Suppression of dsRNA response genes and innate immunity following
Oct4, Stella, and Nanos2 overexpression in mouse embryonic fibroblasts”. Cytokine.
(2018); 106:1-1.
Ebrahimzadeh-Vesal R, Hosseini S, Moghaddassian M, Abbaszadegan MR. “Identification
of novel missense HEXB gene mutation in Iranian-child with juvenile Sandhoff disease”.
Meta Gene 30, no.12 (2017):83-7.
Khalilipour N, Baranova A, Jebelli A, Heravi-Moussavi A, Bruskin S, Abbaszadegan MR.
“Familial esophageal squamous cell carcinoma with damaging rare/germline mutations in
M.R. Abbaszadegan Page 10 of 26
KCNJ12/KCNJ18 and GPRIN2 genes”. Cancer Genetics. (2017); doi:
10.1016/j.cancergen.2017.11.011. Epub 2017
Bagerabad MB, Tavakolian S, Abbaszadegan MR, Kerachian MA. “Promoter
Hypermethylation of the Eyes Absent 4 Gene is a Tumor-Specific Epigenetic Biomarker in
Iranian Colorectal Cancer Patients”. Acta Medica Iranica 56, no.1 (2018):21-7.
Tafazoli A, Eshraghi P, Pantaleoni F, Vakili R, Moghaddassian M, Ghahraman M, Muto V,
Paolacci S, Golyan FF, Abbaszadegan MR. Novel mutations and their genotype-phenotype
correlations in patients with Noonan syndrome, using next-generation sequencing. Adv Med
Sci. 2017 Sep 26; 63(1):87-93. doi: 10.1016/j.advms.2017.07.001. [Epub ahead of print]
Karami Madani G, Rad A, Molavi M, Ardalan Khales S, Abbaszadegan MR, Forghanifard
MM. Predicting the Correlation of EZH2 and Cancer Stem Cell Markers in Esophageal
Squamous Cell Carcinoma. J Gastrointest Cancer. (2017) doi: 10.1007/s12029-017-9985-y.
[Epub ahead of print]
Abbaszadegan MR, Moghbeli M. “Role of MAML1 and MEIS1 in Esophageal Squamous
Cell Carcinoma Depth of Invasion”. Pathol Oncol Res. (2017) doi: 10.1007/s12253-017-
0243-1. [Epub ahead of print]
Houshmand M, Abbaszadegan MR, Kerachian MA. “Assessment of Bone Morphogenetic
Protein 3 Methylation in Iranian Patients with Colorectal Cancer.” Middle East J Dig Dis 9,
no.3 (2017):158-163.
Moghbeli M, Naghibzadeh B, Ghahraman M, Fatemi S, Taghavi M, Vakili R,
Abbaszadegan MR. "Mutations in HNF1A Gene are not a Common Cause of Familial
Young-Onset Diabetes in Iran." Indian Journal of Clinical Biochemistry (2017): 1-5.
Forouzanfar, Narjes, Ancha Baranova, Saman Milanizadeh, Alireza Heravi-Moussavi, Amir
Jebelli, Abbaszadegan MR. "Novel candidate genes may be possible predisposing factors
revealed by whole exome sequencing in familial esophageal squamous cell carcinoma."
Tumor Biology 39, no. 5 (2017): 1010428317699115.
Zeynalzadeh M, Tafazoli A, Aarabi A, Moghaddassian M, Ashrafzadeh F, Houshmand M,
Taghehchian N, Abbaszadegan MR. “Four novel mutations of the BCKDHA, BCKDHB
and DBT genes in Iranian patients with syrup urine disease”. Journal of Pediatric
Endocrinology and Metabolism 31, no.2 (2018):205-212.
Izadpanah MH, Abbaszadegan MR, Fahim Y, Forghanifard MM. “Ectopic expression of
TWIST1 upregulates the stemness marker OCT4 in the esophageal squamous cell carcinoma
cell line KYSE30”. Cellular & molecular biology letters 22, no.1 (2017):33.
Maroofian R, Riemersma M, Jae LT, Zhianabed N, Willemsen MH, Wissink-Lindhout WM,
Willemsen MA, de Brouwer AP, Mehrjardi MY, Ashrafi MR, Kusters B, Kleefstra T,
Jamshidi Y, Nasseri M, Pfundt R, Brummelkamp TR, Abbaszadegan MR, Lefeber DJ, van
Bokhoven H. “B3GALNT2 mutations associated with non-syndromic autosomal recessive
M.R. Abbaszadegan Page 11 of 26
intellectual disability reveal a lack of genotype–phenotype associations in the muscular
dystrophy-dystroglycanopathies”. Genome medicine. 9, no.1 (2017):118.
Tafazoli, Alireza, Peyman Eshraghi, Zahra Kamel Koleti, Abbaszadegan MR. "Noonan
syndrome–a new survey." Archives Med Science: AMS 13, no. 1 (2017): 215.
Bidokhti, Mahnaz Hashemi, Abbaszadegan MR, Noorieh Sharifi, Soodabeh Abbasi Sani,
Mohammad Mahdi Forghanifard. "Contribution of MAML1 in esophageal squamous cell
carcinoma tumorigenesis." Annals of Diagnostic Pathology 27 (2017): 79-82.
Sheibani, Shoaleh, Reihaneh Alsadat Mahmoudian, Abbaszadegan MR, Jamshidkhan
Chamani, Bahram Memar, Mehran Gholamin. "Expression analysis of matrix
metalloproteinase-13 in human gastric cancer in the presence of Helicobacter Pylori
infection." Cancer Biomarkers 18, no. 4 (2017): 349-356.
Shirkani, Afshin, Atena Mansouri, Abbaszadegan MR, Reza Faridhosseini, Farahzad
Jabbari Azad, and Mehran Gholamin. "GATA3 Gene Polymorphisms Associated with
Allergic Rhinitis in an Iranian Population." Reports of Biochemistry & Molecular Biology 5,
no. 2 (2017): 97.
Abbaszadegan MR, Bagheri V, Mahya Shariat Razavi, Amir Abbas Momtazi, Amirhossein
Sahebkar, Mehran Gholamin. "Isolation, identification, and characterization of cancer stem
cells: a review." J cellular physiology 8(232) (2016).
Khorashad, Behzad S., Ghasem M. Roshan, Alistair G. Reid, Zahra Aghili, Mehran
Hiradfar, Mozhgan Afkhamizadeh, Ali Talaei, Azadeh Aarabi, Nosrat Ghaemi, Negin
taghehchian, Hedieh Saberi, Nazanin Farahi, Abbaszadegan MR. "Sexual orientation and
medical history among Iranian people with Complete Androgen Insensitivity Syndrome and
Congenital Adrenal Hyperplasia." Journal of psychosomatic research 92 (2017): 55-62.
Moghbeli, Meysam, Somaye Chavoshi, Mahmud Tavallaie, Ezzat Dadkhah, Reza
Raeissosadati, Moein Farshchian, Mohsen Towliat Kashani, Abbaszadegan MR. "Guanylyl
Cyclase C as a tumor marker for detection of circulating tumor cells in the peripheral blood
of colorectal cancer patients." International Journal of Cancer Therapy and Oncology 4, no.
4 (2016).
Sahebi, Reza, Mahshid Malakootian, Baharak Balalaee, Alireza Shahryari, Masoud
Khoshnia, Abbaszadegan MR, Abdolvahab Moradi, and Seyed Javad Mowla. "Linc-ROR
and its spliced variants 2 and 4 are significantly up-regulated in esophageal squamous cell
carcinoma." Iranian journal of basic medical sciences 19, no. 10 (2016): 1131.
Najafi M, Abbaszadegan MR, Abolfazl Rad, Mahtab Dastpak, Samaneh Boroumand-
Noughabi, Forghanifard MM. "Crosstalk between SHH and stemness state signaling
pathways in esophageal squamous cell carcinoma." Journal of cell communication and
signaling 11, no. 2 (2017): 147-153.
Khorashad, Behzad S., Zahra Aghili, Baudewijntje PC Kreukels, Mehran Hiradfar, Ghasem
M. Roshan, Mozhgan Afkhamizadeh, Abbaszadegan MR, Nosrat Ghaemi, Behnaz Khazai,
M.R. Abbaszadegan Page 12 of 26
and P. T. Cohen-Kettenis. "Psychosexual Outcome among Iranian Individuals With 5α-
Reductase Deficiency Type 2 and its Relationship With Parental Sexism." The Journal of
Sexual Medicine 13, no. 11 (2016): 1629-1641.
Keyfi F, Abbaszadegan MR, Arndt Rolfs, Slobodanka Orolicki, Morteza Moghaddassian,
Abdolreza Varasteh. "Identification of a novel deletion in the MMAA gene in two Iranian
siblings with vitamin B12-responsive methylmalonic acidemia." Cellular & Molecular
Biology Letters 21, no. 1 (2016): 4.
Forghanifard MM, Abolfazl Rad, Moein Farshchian, Maryam Khaleghizadeh, Mehran
Gholamin, Meysam Moghbeli, Abbaszadegan MR. "TWIST1 upregulates the MAGEA4
oncogene." Molecular carcinogenesis 56, no. 3 (2017): 877-885.
Nariman-Saleh-Fam Z, Bastami M, Somi MH, Behjati F, Mansoori Y, Daraei A, Saadatian
Z, Nariman-Saleh-Fam L, Mahmoodzadeh H, Makhdoumi Y, Tabrizi FV, Ebrahimi-Sharif
B, Hezarian A, Naghashi S, Abbaszadegan MR, Tavakkoly-Bazzaz J. “miRNA-Related
Polymorphisms in miR-423 (rs6505162) and PEX6 (rs1129186) and Risk of Esophageal
Squamous Cell Carcinoma in an Iranian Cohort”. Genetic testing and molecular biomarkers
21, no. 6 (2017):382-90.
Rad, Abolfazl, Saeed Esmaeili Dizghandi, Abbaszadegan MR, Negin Taghechian, Maryam
Najafi, Forghanifard MM. "SOX1 is correlated to stemness state regulator SALL4 through
progression and invasiveness of esophageal squamous cell carcinoma." Gene 594, no. 2
(2016): 171-175.
Moghbeli, Meysam, Abolfazl Rad, Moein Farshchian, Negin Taghehchian, Mehran
Gholamin, Abbaszadegan MR. "Correlation between Meis1 and Msi1 in esophageal
squamous cell carcinoma." Journal of gastrointestinal cancer 47, no. 3 (2016): 273-277.
Nariman-Saleh-Fam, Ziba, Milad Bastami, Mohammad Hossein Somi, Naser Samadi,
Abbaszadegan MR, Farkhondeh Behjati, Hamid Ghaedi, Javad Tavakkoly-Bazzaz, Andrea
Masotti. "In silico dissection of miRNA targetome polymorphisms and their role in
regulating miRNA-mediated gene expression in esophageal cancer." Cell Biochemistry and
Biophysics 74, no 4 (2016): 483-497.
Moghbeli, Meysam, Abbaszadegan MR, Ebrahim Golmakani, and Mohammad Mahdi
Forghanifard. "Correlation of Wnt and NOTCH pathways in esophageal squamous cell
carcinoma." Journal of cell communication and signaling 10, no. 2 (2016): 129-135.
Moaven, Omeed, Hamid Raziee, Wilbur Bowne, Abbaszadegan MR, and Bryan C. Fuchs.
"Disease Biomarkers in Gastrointestinal Malignancies." Disease Markers 2016 (2016).
Aghdam, Maryam Nasiri, Abbaszadegan MR, Alireza Tafazoli, Mohammad Aslzare, and
Zohreh Mosavi. "Presence of the RET Cys634Tyr mutation and Gly691Ser functional
polymorphism in Iranian families with multiple endocrine neoplasia type 2A." Hormones
(Athens, Greece) 15, no. 1 (2016): 65.
M.R. Abbaszadegan Page 13 of 26
Sedighi, Maryam., Seyye Amir Aledavood, Abbaszadegan MR, Bahram Memar, Mahdi
Montazer, Mohammad Rajabian, and Mehran Gholamin. "Matrix Metalloproteinase-13-A
Potential Biomarker for Detection and Prognostic Assessment of Patients with Esophageal
Squamous Cell Carcinoma." Asian Pacific journal of cancer prevention: APJCP 17, no. 6
(2016): 2781.
Forghanifard, Mohammad Mahdi, Elham Emami Vahid, Ezzat Dadkhah, Mehran Gholamin,
Samaneh Broumand Noghabi, Martha Ghahraman, Mehdi Farzadnia, Abbaszadegan MR.
"Loss of heterozygosity and microsatellite instability as predictive markers among Iranian
esophageal cancer patients." Iranian Journal of Basic Medical Sciences 19, no. 7 (2016):
726-733.
Abbasi Sani Soodabeh, Mohammad Mahdi Forghanifard, Noorieh Sharifi, Mahnaz Hashemi
Bidokhti, Alireza Jian Bagherpoor, Abbaszadegan MR. "Investigation of melanoma-
associated antigen A4 cancer/testis antigen clinical relevance in esophageal squamous cell
carcinoma." Journal of Cancer Research and TherapeuticsOpen AccessVolume 14, Issue 5,
July-September 2018, Pages 1059-1064
Mahmoudian, Reihaneh Alsadat, Abbaszadegan MR, Mehran Gholamin. "Applying
Subtractive Hybridization Technique to Enrich and Amplify Tumor-Specific Transcripts of
Esophageal Squamous Cell Carcinoma." Pathology & Oncology Research 23, no. 2 (2017):
271-279.
Forghanifard MM, Sima Ardalan Khales, Moein Farshchian, Abolfazl Rad, Masoud
Homayouni-Tabrizi, Abbaszadegan MR. "Negative regulatory role of TWIST1 on SNAIL
gene expression." Pathology & Oncology Research 23, no. 1 (2017): 85-90.
Ghahraman M, Abbaszadegan MR, Vakili R, Hosseini S, Fardi Golyan F, Ghaemi N,
Forghanifard MM. "Identification of four novel mutations of the WFS1 gene in Iranian
Wolfram syndrome pedigrees." Acta diabetologica 53, no. 6 (2016): 899-904.
Moghbeli, Meysam, Ali Sadrizadeh, Mohammad Mahdi Forghanifard, Hooman Mosannen
Mozaffari, Ebrahim Golmakani, Abbaszadegan MR. "Role of Msi1 and PYGO2 in
esophageal squamous cell carcinoma depth of invasion." Journal of cell communication and
signaling 10, no. 1 (2016): 49-53.
Mallak, Afsaneh Javdani, Abbaszadegan MR, Pegah Naeemi Khorasanizadeh, and
Mohammad Mahdi Forghanifard. "Contribution of EVX1 in Aggressiveness of Esophageal
Squamous Cell Carcinoma." Pathology & Oncology Research 22, no. 2 (2016): 341-7.
Rad A, Farshchian M, Forghanifard MM, Matin MM, Bahrami AR, Dirk Geerts, A’rabi A,
Memar B, Abbaszadegan MR. "Predicting the molecular role of MEIS1 in esophageal
squamous cell carcinoma." Tumor Biology 37, no. 2 (2016): 1715-25.
Barooei, Roghayeh, Reihaneh Alsadat Mahmoudian, Abbaszadegan MR, Atena Mansouri,
and Mehran Gholamin. "Evaluation of thymic stromal lymphopoietin (TSLP) and its
correlation with lymphatic metastasis in human gastric cancer." Medical Oncology 32, no. 8
(2015): 217.
M.R. Abbaszadegan Page 14 of 26
Khaleghizadeh M, Abbaszadegan MR, Gholamin M, Forghanifard MM. "Isolation and
Cloning of Human Developmental Pluripotency Aassociated-2 Cancer Testis Gene." ژنتیک .در هزاره سوم
Moghbeli, Meysam, Mohammad Mahdi Forghanifard, Ali Sadrizadeh, Hooman Mosannen
Mozaffari, Ebrahim Golmakani, Abbaszadegan MR. "Role of Msi1 and MAML1 in
Regulation of Notch Signaling Pathway in Patients with Esophageal Squamous Cell
Carcinoma." Journal of gastrointestinal cancer 46, no. 4 (2015): 365-9.
Haghnejad L, Emamalizadeh B, Jamshidi J, Bidoki AZ, Ghaedi H, Ahmadi E, Abdollahi S,
Shahmohammadibeni N, Taghavi S, Fazeli A, Motallebi M, Zarneh AE,
Mohammadihosseinabad S, Abbaszadegan MR, Torkamandi S, Gavenaroudi MA, Pedram
N, Shahidi GA, Tafakhori A, Darvish H, Movafagh A. Variation in the miRNA-433 binding
site of FGF20 is a risk factor for Parkinson's disease in Iranian population. J Neurol Sci. 15;
355(2015):72-4.
Masoud Homayouni-Tabrizi, Ahmad Asoodeh, Abbaszadegan MR, Khadijeh
Shahrokhabadi, and Mahboobeh Nakhaie Moghaddam. "An identified antioxidant peptide
obtained from ostrich (Struthio camelus) egg white protein hydrolysate shows wound
healing properties." Pharmaceutical biology 53, no. 8 (2015): 1155-62.
Saeedeh Ghazaey, Fatemeh Keify, Farzaneh Mirzaei, Masumeh Maleki, Semiramis Tootian,
Mitra Ahadian, Abbaszadegan MR. "Chromosomal analysis of couples with repeated
spontaneous abortions in northeastern Iran." International journal of fertility & sterility 9,
no. 1 (2015): 47.
Mahmoudian, Reihaneh, Abbaszadegan MR, Atena Mansouri, and Mehran Gholamin.
"Amplification of Tumor Transcripts from Limited Quantity of Esophageal Squamous Cell
Carcinoma Tissue Samples." American Journal of Cancer Science 4, no. 1 (2015): 54-62.
Mehran Gholamin, Ali Bazi, Abbaszadegan MR. "Idiopathic lymphocytopenia." Current
opinion in hematology 22, no. 1 (2015): 46-52.
Forghanifard MM, Taleb S, Abbaszadegan MR. "Notch Signaling Target Genes are
Directly Correlated to Esophageal Squamous Cell Carcinoma Tumorigenesis." Patholgy &
Oncology Research. 21, no. 2 (2015):463-7.
Atena Mansouri, Foroughmand AM, Abbaszadegan MR, Bahram Memar, Reyhaneh
Mahmoodian, Mehran Gholamin; Expression analysis of CD44 isoforms S and V3, in
patients with esophageal squamous cell carcinoma. Iran J Basic Med Sci. 18, no. 4 (2015):
380-4.
Homayouni-Tabrizi, Masoud, Ahmad Asoodeh, Abbaszadegan MR, Khadijeh
Shahrokhabadi, Mahboobeh Nakhaei Moghaddam. “Identification of New Angiotansin-1
Converting Enzyme Inhibitory Peptide from Ostrich Egg White Protein Hydrolysate.”
Journal of Isfahan Medical School 32, no 301 (2014): 1-13
M.R. Abbaszadegan Page 15 of 26
Torkamandi S, Meysam Moghbeli, Moein Farshchian, Abolfazl Rad, Abbaszadegan MR.
"Role of Brg1 in progression of esophageal squamous cell carcinoma." Iranian journal of
basic medical sciences 17, no. 11 (2014): 912.
Zand-Karimi MR, Reza Faridhosseini, Abbaszadegan MR, Afshin Shirkani, Anali Riyahi,
Mehdi Montazar, Gholamin M. "Association of ADAM33 gene polymorphisms with
allergic asthma." Iranian Journal of Basic Medical Sciences 17, no. 9 (2014): 716-721.
Mansouri A, Abbaszadegan MR, Jamshid Sorouri Khorashad, Bahram Memar and Mehran
Gholamin. “The expression levels of CD44V6 are correlated with tumor invasion in
esophageal squamous cell Carcinoma patients.” afinidad 80, no. 574 (2014): 1186-1190.
Mansouri A, Abbaszadegan MR, Mehran Gholamin. "A Review on the Biology of Cancer
Stem Cells." Stem Cell Discovery 4, no. 04 (2014): 83.
Forghanifard MM, Mehran Gholamin, Omeed Moaven, Moein Farshchian, Martha
Ghahraman, Amir Aledavood, Abbaszadegan MR. "Neoantigen in esophageal squamous
cell carcinoma for dendritic cell-based cancer vaccine development." Medical Oncology 31,
no. 10 (2014): 191.
Sima Ardalan Khales, Abbaszadegan MR, Abbas Abdollahi, Reza Raeisossadati, Mohsen
Fallah Tousi, and Mohammad Mahdi Forghanifard. "SALL4 as a new biomarker for early
colorectal cancers." Journal of cancer research and clinical oncology141, no.2 (2014):229-35.
Taleb S, Abbaszadegan MR, Meysam Moghbeli, Nasim Hayati Roudbari, Forghanifard
MM. "HES1 as an Independent Prognostic Marker in Esophageal Squamous Cell
Carcinoma." Journal of gastrointestinal cancer 45, no. 4 (2014): 466-471.
Meysam Moghbeli, Faezeh Moghbeli, Mohammad Mahdi Forghanifard, Abbaszadegan
MR. "Cancer stem cell detection and isolation." Medical Oncology 31, no. 9 (2014): 69.
Kolsoum Rezaie Kahkhaie, Omeed Moaven, Abbaszadegan MR, Mehdi Montazer, and
Mehran Gholamin. "Specific MUC1 splice variants are correlated with tumor progression in
esophageal cancer." World Journal of surgery 38, no. 8 (2014): 2052-2057.
Mahdi Daliri, Abbaszadegan MR, Mostafa Mehrabi Bahar, Azadeh Arabi, Mona
Yadollahi, Azar Ghafari, Negin Taghehchian, and Seyed Rasoul Zakavi. "The role of BRAF
V600E mutation as a potential marker for prognostic stratification of papillary thyroid
carcinoma: a long-term follow-up study." Endocrine research 39, no. 4 (2014): 189-193.
Forghanifard MM, Ardalan Khales S, Javdani-Mallak A, Rad A, Farshchian M,
Abbaszadegan MM. "Stemness state regulators SALL4 and SOX2 are involved in
progression and invasiveness of esophageal squamous cell carcinoma." Medical Oncology
31, no. 4 (2014): 922.
Raeisossadati R, Abbaszadegan MR, Meysam Moghbeli, Alireza Tavassoli, Alexandre
Hiroaki Kihara, and Mohammad Mahdi Forghanifard. "Aberrant expression of DPPA2 and
M.R. Abbaszadegan Page 16 of 26
HIWI genes in colorectal cancer and their impacts on poor prognosis." Tumor Biology 35,
no. 6 (2014): 5299-5305.
Meysam Moghbeli, Mohammad Mahdi Forghanifard, Azadeh Aarabi, Akram Mansourian,
Abbaszadegan MR. "Clinicopathological sex-related relevance of Musashi1 mRNA
expression in esophageal squamous cell carcinoma patients." Pathology & Oncology
Research 20, no. 2 (2014): 427-433.
Moghaddasian M, Hamidreza Arab, Ezzat Dadkhah, Hamidreza Boostani, Azam Rezaei
Babak, Abbaszadegan MR. "Protein modeling of cathepsin C mutations found in Papillon–
Lefèvre syndrome." Gene 538, no. 1 (2014): 182-187.
Farzin Heravi, Abbaszadegan MR, Mohsen Merati, Nadia Hasanzadeh, Ezzat Dadkhah,
and Farzaneh Ahrari. "DNA Damage in Oral Mucosa Cells of Patients with Fixed
Orthodontic Appliances." Journal of dentistry (Tehran, Iran) 10, no. 6 (2013): 494.
Sahar Shekouhi, Fatemeh Baghbani, Mohammad Hasanzadeh Nazar-Abadi, Tayebeh
Hamzehloie, Abbaszadegan MR, Nafiseh Saghafi, Reza Raoofian et al. "Identification of
Xq22. 1-23 as a region linked with hereditary recurrent spontaneous abortion in a family."
Iranian Journal of Reproductive Medicine 11, no. 8 (2013): 659.
Moghbeli M, Moaven O, Memar B, Raziei HR, Aarabi A, Dadkhah E, Forghanifard MM,
Manzari F, Abbaszadegan MR. “Role of hMLH1 and E-cadherin promoter methylation in
the gastric cancer progression.” J Gastrointestinal cancer 45, no. 1 (2013):40-47.
Simin Mohseni, Abbaszadegan MR, Bahram Memar, Akram Mansourian, and Mehran
Gholamin. "Expression analysis of histidine decarboxylase in esophageal squamous cell
carcinoma patients." Annals of Biological Research, no. 4 (2013): 36-40
Saeedeh Ghazaey, Farzaneh Mirzaei, Mitra Ahadian, Fatemeh Keifi, Tootian Semiramis,
Abbaszadegan MR. "Pattern of chromosomal aberrations in patients from north East iran."
Cell Journal (Yakhteh) 15, no. 3 (2013): 258.
Hossein Naseh, Bahram Memar, Reza Bagheri, Mehdi Montazer, Abbaszadegan MR. "A
Cancer-Array Approach Elucidates the Immune Escape Mecha-nism and defects in the DNA
Repair System in Esophageal Squa-mous Cell Carcinoma." Archives of Iranian medicine 16,
no. 8 (2013): 463.
Moghbeli M, Abbaszadegan MR, Farshchian M, Montazer M, Raeisossadati R, Abdollahi
A, Forghanifard MM. "Association of PYGO2 and EGFR in esophageal squamous cell
carcinoma." Medical Oncology 30, no. 2 (2013): 1-9.
Forghanifard MM, Moghbeli M, Raeisossadati R, Tavassoli A, Javdani Mallak A,
Boroumand-Noughabi S, Abbaszadegan MR. "Role of SALL4 in the progression and
metastasis of colorectal cancer." J Biomed Sci 20, no. 6 (2013): 922.
Nosrat Ghaemi, Martha Ghahraman, Abbaszadegan MR, Alireza Baradaran-Heravi, and
Rahim Vakili. "Novel Mutation in the SLC19A2 Gene in an Iranian Family with Thiamine-
M.R. Abbaszadegan Page 17 of 26
Responsive Megaloblastic Anemia: A Series of Three Cases." Journal of clinical research in
pediatric endocrinology 5, no. 3 (2013): 199.
Meysam Moghbeli, Faezeh Moghbeli, Mohammad Mahdi Forghanifard, Ali Garayali,
Abbaszadegan MR. "Cancer stem cell markers in esophageal cancer." American Journal of
Cancer Science 2, no. 1 (2013): 37-50.
Abbaszadegan MR, Soolmaz Hassani, Rahim Vakili, Mohammad Reza Saberi, Alireza
Baradaran-Heravi, Azadeh A’rabi, Mahin Hashemipour et al. "Two novel mutations in
CYP11B1 and modeling the consequent alterations of the translated protein in classic
congenital adrenal hyperplasia patients." Endocrine 44, no. 1 (2013): 212-219.
Houshang Rafatpanah, Abdolrahim Rezaee, Mohammad Mehdi Etemadi, Reza Farid
Hosseini, Bita Khorram, Leila Afsahr, Graham Taylor, Naser Mokhber, Mahmoud
Mahmoudi, Abbaszadegan MR and et al. "The impact of interferon-alpha treatment on
clinical and immunovirological aspects of HTLV-1-associated myelopathy in northeast of
Iran." Journal of neuroimmunology 250, no. 1 (2012): 87-93.
Nosrat Ghaemi, Martha Ghahraman, Abbaszadegan MR, Alireza Baradaran, and Rahim
Vakili. "Novel mutation in the SLC19A2 gene in Thiamine-responsive megaloblastic
anemia (Rogers’ syndrome)." Iranian Journal of Neonatology 1, no. 3 (2012): 30-35.
Rahim Vakili, Martha Ghahraman, Nosrat Ghaemi, Batool Faraji, Mahin Hashemi poor, Elham
Ahmadi, Abbaszadegan MR, Masumeh Saeidi, and Bahram Naghibzadeh. "Clinical and
Molecular Genetic Analysis of Iranian Neonatal Diabetic Cases Demonstrating Mutations in
KCNJ11 gene." Iranian Journal of Neonatology Vol 3, no. 2 (2012): 85-90.
Nosrat Ghaemi, Rahim Vakili, Daniel Zamanfar, Abaszadegan MR, Marta Ghahraman, and
Benyamin Mohseni Saravi. "Roger’s Syndrome and Report of 3 Cases in Children." J
Mazandaran Univer Med Sciences, no. 89 (2012):27-31.
Nosrat Ghaemi, Samaneh Noroozi Asl, Abbaszadegan MR, Marta Ghahraman, and Rahim
Vakili. "GPR54 Gene Mutations in Iranian Girls with Central Familial Precocious Puberty."
Iranian Journal of Obstetrics, Gynecology & Infertility 15, no. 28 (2012): 31-33.
Forghanifard MM, Jafar Amani, Elaheh Gheybi, Abbaszadegan MR. "In silico analysis of
chimeric polytope of cancer/testis antigens for dendritic cell-based immune-gene therapy
applications." Gene Therapy and Molecular Biology 14 (2012): 87-96.
Ezzat Dadkhah, Masood Ziaee, Mohammad Hossein Davari, Toba Kazemi, Abbaszadegan
MR. "Informative STR Markers for Marfan Syndrome in Birjand, Iran." Iranian journal of
basic medical sciences 15, no. 5 (2012): 1020.
Shokoufeh Bonakdaran, Abbaszadegan MR, Ezzat Dadkhah, and Mohammad Khajeh
Dalouie. "Vitamin D receptor gene polymorphisms in type 1 diabetes mellitus: a new pattern
from Khorasan province, Islamic Republic of Iran." Eastern Mediterrian Health Journal, no.
18 (2012): 614-619
M.R. Abbaszadegan Page 18 of 26
Keify F, Narges Zhiyan, Farzaneh Mirzaei, Semiramis Tootian, Saeedeh Ghazaey,
Abbaszadegan MR. "Two novel familial balanced translocations t (8; 11) (p23; q21) and t
(6; 16) (q26; p12) implicated in recurrent spontaneous abortion." Archives of Iranian
Medicine 15, no. 4 (2012): 249.
Meysam Moghbeli, Mahmood Maleknejad, Azadeh Arabi, Abbaszadegan MR. "Mutational
analysis of uroporphyrinogen III cosynthase gene in Iranian families with congenital
erythropoietic porphyria." Molecular biology reports 39, no. 6 (2012): 6731-6735.
Forghanifard MM, Omeed Moaven, Moein Farshchian, Mehdi Montazer, Reza
Raeisossadati, Abbas Abdollahi, Meysam Moghbeli, Taher Nejadsattari, Kazem Parivar,
Abbaszadegan MR. "Expression analysis elucidates the roles of MAML1 and Twist1 in
esophageal squamous cell carcinoma aggressiveness and metastasis." Annals of surgical
oncology 19, no. 3 (2012): 743-749.
Moghbeli M, Moaven O, Dadkhah E, Farzadnia M, Roshan NM, Asadzadeh-Aghdaee H,
Mehrabi Bahar M, Raeisossadati R, Forghanifard MM, Bakhtiari, Baradaran Heravi A,
Abbaszadegan MR. "High frequency of microsatellite instability in sporadic colorectal
cancer patients in Iran." Genet Mol Res 10, no. 4 (2011): 3520-9.
Forghanifard MM, Gholamin M, Farshchian M, Moaven O, Memar B, Forghani MN,
Dadkhah E, Naseh H, Moghbeli M, Raeisossadati R, Abbaszadegan MR. "Cancer-testis
gene expression profiling in esophageal squamous cell carcinoma: identification of specific
tumor marker and potential targets for immunotherapy." Cancer biology & therapy 12, no. 3
(2011): 191-197.
Reza Raeisossadati, Moein Farshchian, Azita Ganji, Alieza Tavassoli, Arash Velayati, Ezzat
Dadkhah, Somaye Chavoshi, Mostafa Mehrabi Bahar, Bahram Memar, Mohammad Taghi
Rajabi Mashhadi, Hossein Naseh, Mohammad Mahdi Forghanifard, Meysam Moghbeli,
Omeed Moaven, Abbaszadegan MR. "Quantitative analysis of TEM-8 and CEA tumor
markers indicating free tumor cells in the peripheral blood of colorectal cancer patients."
International J colorectal disease 26, no. 10 (2011): 1265-1270.
Abbaszadegan MR, Fatemeh Keify, Farah Ashrafzadeh, Moein Farshchian, Khadivi Zand
Farhad, Mohammad Naser Teymoorzadeh, Faezeh Mojahedi, Mitra Ahadian and Reza
Ebrahimzadeh. "Gene dosage analysis of proximal spinal muscular atrophy carriers using
real-time PCR." Archives of Iranian medicine 14, no. 3 (2011): 188.
Amir Asnaashari, Mohammad Towhidi, Reza Farid-Hosseini, Abbaszadegan MR, Davood
Attaran, Seiedeh Sedigheh Fatemi, and Atefeh Amiri Darban. "Evaluation of Polymerase
Chain Reaction for Diagnosis of “Tuberculous Pleurisy”." Tanaffos 10, no. 1 (2011): 12.
Sahar Shekouhi, Majid Mojarrad, Hasanzadeh Nazar-Abadi M, Tayebeh Hamzeh-loui,
Abbaszadegan MR, Reza Raoofian, Nafiseh Saghafi, and Fatemeh Baghbani. "Tracking of
M.R. Abbaszadegan Page 19 of 26
involved loci in recurrent abortion located on X chromosome in women with X linked
idiopathic recurrent spontaneous abortion." Clinical Biochemistry 44, no. 13 (2011): 286.
Noushin Taghavi, Firouzeh Biramijamal, Masoud Sotoudeh, Omeed Moaven, Hooman
Khademi, Abbaszadegan MR, Malekzadeh R. "Association of p53/p21 expression with
cigarette smoking and prognosis in esophageal squamous cell carcinoma patients." World
journal of gastroenterology: World J Gastroent 16, no. 39 (2010): 4958.
Mehran Gholamin, Omeed Moaven, Moein Farshchian, Mahmoud Mahmoudi, Mojtaba
Sankian, Bahram Memar, Mohammad Naser. Forghani, Reza Malekzadeh, Mohammad
Taher Rajabi-Mashhadi, Abbaszadegan MR. "Induction of cytotoxic T lymphocytes
primed with tumor RNA-loaded dendritic cells in esophageal squamous cell carcinoma:
preliminary step for DC vaccine design." BMC cancer 10, no. 1 (2010): 261.
Noushin Taghavi, Masoud Sotoudeh, Firouzeh Biramijamal, Abbaszadegan MR, Hooman
Khademi, Masoud Sotoudeh, Shahrouz Khoshbakht, and Reza Malekzadeh. "P21
(waf1/cip1) gene polymorphisms and possible interaction with cigarette smoking in
esophageal squamous cell carcinoma in northeastern Iran: a preliminary study." Archives of
Iranian medicine 13, no. 3 (2010): 235.
Omeed Moaven, Hamid Reza Raziee, Hamid Reza Sima, Azita Ganji, Reza Malekzadeh,
Azadeh A’rabi, Abbas Abdollahi, Bahram Memar, Masoud Sotoudeh, Hossein Naseh,
Hamid Nekoui, Adeleh Razavipour, Mehran Gholamin, Ezzat Dadkhah, Moein Farshchian,
Abbaszadegan MR. "Interactions between Glutathione-S-Transferase M1, T1 and P1
polymorphisms and smoking, and increased susceptibility to esophageal squamous cell
carcinoma." Cancer epidemiology 34, no. 3 (2010): 285-290.
Noushin Taghavi, Firouzeh Biramijamal, Masoud Sotoudeh, Hooman Khademi, Reza
Malekzadeh, Omeed Moaven, Bahram Memar, Azadeh A'rabi, Abbaszadegan MR.
"P16INK4a hypermethylation and p53, p16 and MDM2 protein expression in esophageal
squamous cell carcinoma." BMC cancer 10, no. 1 (2010): 138.
Gholamin M, Moaven O, Farshchian M, Rajabi MT, Mahmoudi M, Sankian M, Sazgarnia
A, Ghahreman M, Abbaszadegan MR. "Highly efficient transfection of dendritic cells
derived from esophageal squamous cell carcinoma patient: optimization with green
fluorescent protein and validation with tumor RNA as a tool for immuno-genetherapy." Iran
J Biotechnol 8 (2010): 121-126.
Mitra Naseri, Gian Marco Ghiggeri, Gianluca Caridi, Abbaszadegan MR. "Five cases of
severe vesico-ureteric reflux in a family with an X-linked compatible trait." Pediatric
Nephrology 25, no. 2 (2010): 349-352.
Abbaszadegan MR, Hamid Asadzadeh Aghdayi, Forough Rastin, Ezzat Dadkhah, Maryam
Lotfalizadeh, Nema Mohamadian Roshan, Mahdi Farzadnia, Arash Velayati, and Azadeh
A'rabi. "Microsatellite Instability in Young Women with Endometrioid type Endometrial
Cancer." Iranian Journal of Public Health 38, no. 3 (2009): 24-30.
M.R. Abbaszadegan Page 20 of 26
Ameri, A., A. Alidousti, K. M. Sheibani, A. G. Motlagh, N. Valaei, M. H. Emranpour,
Abbaszadegan MR, Y. Hosseini, and M. Parvin. "Probing the relation between gene
promoters hypermethylation of RARB and p16 among patients with prostatic cancer of
different prognosis." Pejouhandeh 13, no. 6 (2009): 469-474.
Mohammad Reza Zali, Omeed Moaven, Hamid Asadzadeh Aghdaee, Kamran
Ghafarzadegan, Khadijeh Jami Ahmadi, K, Mehdi Farzadnia, Azadeh Arabi, Abbaszadegan
MR. “Clinicopathological significance of E-cadherin, beta-catenin and p53 expression in
gastric adenocarinoma.” J Res Med Sci 14, no. 4 (2009): 239-247.
Mehran Gholamin, Omeed Moaven, Bahram Memar, Moein Farshchian, Hossein Naseh,
Reza Malekzadeh, Masoud Sotoudeh, Mohammad Taghi Rjabi Mashhadi Mohammad Naser
Forghani, Farid Farokhi, Abbaszadegan MR. "Overexpression and interactions of
interleukin-10, transforming growth factor β, and vascular endothelial growth factor in
esophageal squamous cell carcinoma." World journal of surgery 33, no. 7 (2009): 1439-
1445.
Abbaszadegan MR, Omeed Moaven, Hamid Reza Sima, Kamran Ghafarzadegan, Azadeh
A'rabi, Mohammad Naser Forghani, Hamid Reza Raziee et al. "p16 promoter
hypermethylation: a useful serum marker for early detection of gastric cancer." World
journal of gastroenterology: WJG 14, no. 13 (2008): 2055.
Abbaszadegan MR, Alireza Modarresi, Farhad Khadivi-Zand, Arash Velayati: “Rare gross
deletion in T-cell immune regulator-1 gene in Iranian family with infantile malignant
osteopetrosis.” Saudi Med J 29, no 10, (2008): 1494-1496.
Abbaszadegan MR, Narges Jafarzadeh, Mojtaba Sankian, AbdolReza Varasteh, Mahmoud
Mahmoudi, Majid Sadeghizadeh, Fatemeh Khatami, and Neema Mehramiz. "Truncated
MTA-1: a pitfall in ELISA-based immunoassay of HTLV-1 infection." BioMed Research
International, (2008).
Mohammad Hassan Khazai, Jalil Tavakkol Afshari, Bahram Khazai, Javad Akbarzadeh,
Ladan Khazai, AbbaszadeganMR, Farhad Khadivizand. “IL-4 and interferon gama in
recently diagnosed type-1 diabetes, a case control study.” ARYA Atherosclerosis Journal 3,
no. 1, (2007): 1-7
Tooka Banaei, Darush Farrokh-Tehrani, Abbaszadegan MR. “The Genetics of Age Related
Macular Degeneration.” Bina J Ophthalmol 13, no. 1, (2007): 104-118
Alireza Baradaran‐Heravi, Rahim Vakili, Tiina Robins, Jonas Carlsson, Nosrat Ghaemi,
Azadeh A’rabi, Abbaszadegan MR. "Three novel CYP21A2 mutations and their protein
modelling in patients with classical 21‐hydroxylase deficiency from northeastern Iran."
Clinical endocrinology 67, no. 3 (2007): 335-341.
Abbaszadegan MR, Alireza Tavasoli, Arash Velayati, Hamid Reza Sima, Hassan
Vosooghinia, Mehdi Farzadnia, Hamid Asadzedeh, Mehran Gholamin, Ezzat Dadkhah, and
Azadeh Aarabi. "Stool-based DNA testing, a new noninvasive method for colorectal cancer
screening, the first report from Iran." World journal of gastroenterology: World J Gastr 13,
no. 10 (2007): 1528-1533.
M.R. Abbaszadegan Page 21 of 26
Abbaszadegan MR, Arash Velayati, Alireza Tavasoli, and Ezzat Dadkhah. "Rapid DNA
extraction protocol from stool, suitable for molecular genetic diagnosis of colon cancer."
Iranian Biomedical Journal 11, no. 3 (2007): 203-208.
Abbaszadegan MR, Masood Ziaee, Farhad Khadivi-zand, Zahra Badiee, Bahram Khazaei,
Zohreh Vahedian, Fahimeh Mehrabian and Ezzat Dadkhah. “Carrier detection of hemophilia
in Tyme A southern Khorasan using the 3 polymorphic sites of BclI, HindIII, and AlwNI.”
Blood 3, no. 4, (2007): 291-298.
Kamalidehghan B., Houshmand M., Panahi MS., Abbaszadegan MR, Ismail P., Shiroudi
MB.: TheY8.9 kb Deletion in Tumoral Cell mtDNA Is More Common than Other Deletions
in Gastric Cancer. Archives Med Res 37(7), 848-53 (2006).
Leyla Mostaan, Sefat, Abbaszadegan MR, Kamran Ghafarzadegan, Mohammad Seyedi,
Azadeh Aarabi, Maryam Salehi, and Monavar Afzal Aghaie. "Paper: Evaluationof E-
cadherin and its correlation with lymphatic metastasis and tumor grade in laryngeal SCC.” Ir
J. Otorhinolaryngology 18, no 44, (2006): 61-66
Mahdi Kahrom, Abbaszadegan MR, Hadi Kahrom, and Rahim Vakili. "Nager's acrofacial
dysostosis with hypertrophic cardiomyopathy." Saudi medical journal 27, no. 10 (2006):
1578-1581.
Abbaszadegan MR, Hamid Reza Raziee, Kamran Ghafarzadegan, Mohammad Taghi
Shakeri, Sima Afsharnezhad, and Mohammad Reza Ghavamnasiry. "Aberrant p16
methylation, a possible epigenetic risk factor in familial esophageal squamous cell
carcinoma." International journal of gastrointestinal cancer 36, no. 1 (2005): 47-53.
Rahim Vakili, Alireza Baradaran-Heravi, Babak Barid-Fatehi, Mehran Gholamin, Nosrat
Ghaemi, Abbaszadegan MR. "Molecular analysis of the CYP21 gene and prenatal
diagnosis in families with 21-hydroxylase deficiency in northeastern Iran." Hormone
research 63, no. 3 (2004): 119-124.
Houshang Rafatpanah, Vera Pravica, Reza Farid Hosseini, Abbaszadegan MR, Abbas
Tabatabaei, Abbas Goharjoo, Mohammed Mehdi Etemadi, and Ian V. Hutchinson.
"Association of a novel single nucleotide polymorphism in the human perforin gene with the
outcome of HTLV-I infection in patients from northeast Iran (Mash-had)." Human
immunology 65, no. 8 (2004): 839-846.
Ghaffarzadegan K, Zali MR, Jami Al-Ahmadi K, Hamid Asadzadeh, Abbaszadegan MR.
"Correlation of nuclear P53 Immunoreaction with the histopathologic features in gastric
carcinoma." Archives of Iranian Medicine 7, no. 4 (2004): 279-283.
Abbaszadegan MR, Hamid Reza Raziee, Kamran Ghafarzadegan, and Mohammad Reza
Ghavamnasiry. "p16/INK4a promoter hypermethylation in serum, blood and tumor of
patients with esophageal squamous cell carcinoma." IJBMS 6, no. 4 (2004): 4-9.
M.R. Abbaszadegan Page 22 of 26
Abbaszadegan MR, Omidi A, Niyazi A, Zoheidi MR, Gholamin M, Jami-Ahmadi K,
Ghaffarzadegan K: Prevalence of Human Papilloma Virus type 16 and 18 and expression of
mutant p53 in Esophageal Squamous Cell Carcinoma. Ir J. Basic Med Sci 4(6), 38-42 (2004)
Abbaszadegan MR, Mehran Gholamin, Abbas Tabatabaee, Reza Farid, Massoud Houshmand,
and Morteza Abbaszadegan. "Prevalence of human T-lymphotropic virus type 1 among blood
donors from Mashhad, Iran." Journal of clinical microbiology 41, no. 6 (2003): 2593-2595.
Abbaszadegn MR, Nazanin Pazouki and Mojtaba Sankian. “DNA extraction from Mutation
Detection Enhancement (MDE) gel stained with silver nitrate.” Protocol Online, (2003).
Hamid Yazdani, Daniel C. Chung, Do, Abbaszadegan MR, Kholoud Al-Khayer, Wai-Man
Chan, Milad Yazdani, Kazem Ghodsi, Elizabeth Engele and Elias Traboulsi E. “ A novel
PHOX2A/ARIX mutation in an Iranian family with Congenital Fibrosis of Extraocular
Muscles type 2-CFEOM2.” The American J Ophthalmology 5, no. 136, (2003): 861865
Farah Ashrafzade, Abbaszadegan MR, Nosrat Ghaemi. “Fragile X Syndrome a case report
with fingers anomaly.” Hamedan University Med. Science J 16, no. 2, (2003): 132-134.
Gelmann, David J. Steadman, Jing Ma, Natalie Ahronovitz, H. James Voeller, Sheridan
Swope, Abbaszadegan MR, Kevin M. Brown, Kate Strand, Richard B. Hayes, and Meir J.
Stampfer. “Occurrence of NKX3.1 C154T polymorphism M. R. in men with and without
prostate cancer and studies of its effect on protein function.” Cancer Res 62, no.9, (2002):
2654-9.
Farhad Farid-Hosseini, Pishnamaz Razieh, Reza Farid-Hosseini, Abbaszadegan MR,
Mahmoud Mahmoodi and Maryam Rasteen. “Expression of Interleukin-2R chain (CD25) on
peripheral blood lymphocytes in HTLV-I associated myelopathy/Tropical Spastic Paraparesis
patients.” Arch Ir Med 4, no. 4, (2001): 183-187.
Abbaszadegan MR, Shirdel A., Jamshid Soroori, Behjat Gholami and Mehran Gholamin.
“Detection of minimal residual disease in CML patients after bone marrow transplantation
using a semi-quantitative RT-PCR of BCR-ABL fusion gene (Persian).” Ir J. Basic Med
Sciences 4, no 4, (2001):183-187.
Eva Spitzer, Abbaszadegan MR, Frank Schmidt, Andrea Hauser, Ute Buwitt, Frank‐Roman
Lauter, Kathrin Pötschick, Jutta Krocker, Dirk Elling, and Richard Grosse. "Detection of
BRCA1 and BRCA2 mutations in breast cancer families by a comprehensive two‐stage
screening procedure." International journal of cancer 85, no. 4 (2000): 474-481.
Caryn Lerman, Chanita Hughes, Bruce J. Trock, Ronald E. Myers, David Main, Aba Bonney,
Abbaszadegan MR et al. "Genetic testing in families with hereditary nonpolyposis colon
cancer." JAMA 281, no. 17 (1999): 1618-1622.
Abbaszadegan MR, Abdolreza Varasteh, Mohammad Ali Khoshroo, Behjat Gholami, and
Mehran Gholamin. “Isolation and purification of TAX protein of HTLV-1 virus using
recombinant DNA Techniques.” I.R. Ir Biotechnology 3, (1999): 456-461.
M.R. Abbaszadegan Page 23 of 26
Abbaszadegan MR, Streuwing J., Brown KM., Snider J., Gore-Langton R., Hughes MR.:
Automated detection of highly prevalent mutations in BRCA 1 and 2 genes using a
fluorogenic PCR. Genetic Testing 1, (1998): 171-180.
Abbaszadegan MR, Cress AE., Futscher BW., Bellamy WT., Dalton WS.: Evidence for
cytoplasmic P-glycoprotein location associated with increased multidrug resistance and
resistance to chemosensitizers. Cancer Res 56, (1996): 5435-5442.
Abbaszadegan MR, Anne E. Cress, Bernard W. Futscher, William T. Bellamy, and William
S. Dalton. "Evidence for cytoplasmic P-glycoprotein location associated with increased
multidrug resistance and resistance to chemosensitizers." Cancer research 56, no. 23 (1996):
5435-5442.
Abbaszadegan MR, Bernard W. Futscher, Walter T. Klimecki, Alan List, and William S.
Dalton. "Analysis of multidrug resistance-associated protein (MRP) messenger RNA in
normal and malignant hematopoietic cells." Cancer Research 54, no. 17 (1994): 4676-4679.
Futscher Bernard W, Abbaszadegan MR, Frederick Domann, and William S. Dalton.
"Analysis of MRP mRNA in mitoxantrone-selected, multidrug-resistant human tumor cells."
Biochemical pharmacology 47, no. 9 (1994): 1601-1606.
Abril ER, Scuderi P, Abbaszadegan MR, Watzl B, Earnest DL.”Vitamin A indirectly
activates kupffer cells by stimulating cytokine production by peripheral blood mononuclear
leukocytes.” Cells Hep Sinusoid 3, (1991): 27-29.
Watzl B., Abril ER., Abbaszadegan MR, Scuderi P., Watson RR.” Effects of ethanol in vivo
on TNF secretion by cultured rat kupffer cells.” Cells Hep Sinusoid 3, (1991): 480-482.
CONFERENCE PROCEEDINGS, ABSTRACTS AND PRESENTATIONS
National and International Conference Proceedings; Selected few:
1. Meysam Moghbeli, Ebrahim Golmakani, Hooman Mosannen Mozaffari, Bahram Memar,
Mohammad Mahdi Forghanifard, Mehran Gholamin, Abbaszadegan MR. Role of NOTCH
Pathway in Targeted Therapy against the Esophageal Cancer Stem Cells. International
Nastaran Cancer Symposium-2016.
2. Amir Abbas Hamidi, Abbaszadegan MR, Mehran Gholamin, Bahram Memar, Ali Jangjoo.
Correlation Analysis Between H.Pylori And Expression Changes Of MAML1 And TWIST1
In Gastric Cancer Patients. International Nastaran Cancer Symposium-2016.
3. Ensiye Khorshidi, Reihaneh Alsadat Mahmoudian, Kazem Anvary, Abbaszadegan MR,
Mehran Gholamin. Assessment Of Changes In Isoforms Of MDM2 Gene, Before And After
The Effect Of 5-Fluorouracil In Esophageal Cancer Cell Lines MKYSE-30). International
Nastaran Cancer Symposium-2016.
M.R. Abbaszadegan Page 24 of 26
4. Mahya Shariat Razavi, Mohammad Mahdi Forghanifard, Dor Mohammad Kordi
Tamandani, Abbaszadegan MR. Key Factors In EMT: Critical Process In Breast Cancer
Malignancy. International Nastaran Cancer Symposium-2016.
5. Niloofar Vashahri Ghamsari, Reihaneh Alsadat Mahmoudian, Mohammad Mahdi
Forghanifard, Abbaszadegan MR, Samaneh Boroumand Noghabi, Shirin Taraz-Jamshidi,
Mehran Gholamin. Analysis of SNP Rs2252070 Of MMP13 Gene In Human Esophageal
Squamous Cell Carcinoma In Iranian Population. International Nastaran Cancer
Symposium-2016.
6. Mohammad eosein Izadpanah, Abbaszadegan MR, Mohammad Mahdi Forghanifard.
Impact Of TWIST1 On OCT-4 Gene Expression In Esophageal Carcinoma Cell Line
(KYSE-30). International Nastaran Cancer Symposium-2016.
7. Taghehchian N, Mashkani B, Yaghmaei P, Abbaszadegan MR. Evaluation Of Biological
Activity And Specificity Of Mesenchymal Epithelial Transition (MET) Proto-Oncogene In
KYSE-30 Cell Line. International Nastaran Cancer Symposium-2016.
8. Fahim Y, Abbaszadegan MR, Forghanifard MM. Clinical Significance Of TEAD4
Expression In Human Esophageal Squamous Cell Carcinoma. International Nastaran Cancer
Symposium-2016.
9. Mohammad Mahdi Forghanifard, Mohammad Hossein Izadpanah, Abbaszadegan MR.
Crosstalk Between EMT And Stemness State In Esophageal Squamous Cell Carcinoma.
International Nastaran Cancer Symposium-2016.
10. Reihaneh Alsadat Mahmoudian, Abbaszadegan MR, Mohammad Mahdi Forghanifard,
Meysam Moghbeli, Faezeh Moghbeli, Mehran Gholamin. Biological And
Clinicopathological Significance Of Cripto-1 Expression In The Progression Of Human
ESCC. International Nastaran Cancer Symposium-2016.
11. Fatemeh Mollaei, Mohammad Mahdi Forghanifard, Abbaszadegan MR. Molecular
Pathways In Gastric Cancer. International Nastaran Cancer Symposium-2016.
12. Fatemeh Fardi Golyan, Morteza Moghaddassian, Mohamad Mahdi Forghanifard, Samaneh
Talebi, Abbaszadegan MR. Whole-Exome Sequencing Reveals A Novel Damaging
Mutation un Seprase un A Family With Esophageal Squamous Cell Carcinoma.
International Nastaran Cancer Symposium-2016.
13. Azadeh Aarabi, Bahram Memar, Rahman Nooraie, Ezzat Dadkhah, Abbaszadegan MR.
Role of INPP5A in progression of esophageal squamous cell carcinoma. 1st International
Nastaran Cancer Symposium-2015
14. Negin Taghehchian, Mohammad Mahdi Forghanifard, Nooriehsharifi Sistani,
Abbaszadegan MR. Immunohistochemical Analysis of Transcription Factors TWIST1
Protein Expression in Esophageal Squamous Cell Carcinoma Patient. 1st International
Nastaran Cancer Symposium-2015
M.R. Abbaszadegan Page 25 of 26
15. Fatemeh Fardi Golyan, Mohamad Mehdi Forghanifar, Abbaszadegan MR. Identification of
Survivin Polymorphism in familial esophageal cancer based on Whole-Exome sequencing
data. 1st International Nastaran Cancer Symposium-2015
16. Abbaszadegan MR. Role of cancer susceptibility genes from DNA repair pathway in
familial Esophageal Squamous Cell Carcinoma. Cancer Susceptibility and Cancer
Susceptibility syndromes. 2014
17. Abbaszadegan MR. Cancer Stem Cells. Medical Genetic Congress. Tehran, Iran, 2013
18. Abbaszadegan MR. Probable genetic factors in Esophageal and gastric cancer
epidemiology. International Multidisciplinary Cancer Congress.
19. Abbaszadegan MR. Cancer stem cells. Medical Genetic Congeress. Tehran, Iran, 2012
20. Abbaszadegan MR. Novel gene search in esophageal squamous cell carcinoma. The Third
International Scientific and Practical Conference- postgenome 2012. Kazan, Russia, 2012.
21. Raeisossadat R, Forghanifard M.M, Sardari S, Tavassoli A, Moghbeli M, Abbaszadegan
MR. Developmental pluripotency associated- 2 (DPPA2) gene may be a metastatic marker
for colorectal cancer. European Human Genetics Conference 2012. Nurnberg, Germany,
2012.
22. Moghbeli M, Forghanifard M.M, Raeisossadat R, Broumand S, Abbaszadegan MR. HIWI
as a prognostic marker for early stages of colorectal cancer. European Human Genetics
Conference 2012. Nurnberg, Germany, 2012.
23. Forghanifard MM, Raeisossadat R, Moghbeli M, Tavassoli A, Montazar M, Gholamin M,
Abbaszadegan MR. Elucidation of SALL4 oncogenic role in colorectal cancer; the first
report. European Human Genetics Conference 2012. Nurnberg, Germany, 2012.
24. Dadkhah E, Moghaddasian M, Arab H, Bustani Farkoush H, Kazemi Noughabi M,
Abbaszadegan MR. Novel mutation in cathepsin C gene(CTSC) and modeling of mutated
protein in three Iranian families with Papillon Lefever Syndrome. European Human
Genetics Conference 2012.Nurnberg, Germany, 2012.
25. Abbaszadegan MR, Forghanifard MM. Impact of cancer testis antigens crosstalk with self
renewal cell signaling pathways in esophageal squamous cell carcinoma. European Human
Genetics Conference 2012.Nurnberg, Germany. June 23-26-2012. (Poster presentation).
26. Abbaszadegan MR, Saidi R, Moaven M, A'rabi A, Homaie-Shandiz F. Novel germ line
BRCA2 mutations in familial esophageal squamous cell carcinoma.12th Iranian Congress of
biochemistry & 4th International Congress of Biochemistry and Molecular Biology,
Mashhad, Iran, 2011.
27. Abbaszadegan MR, Ahadian M, Keify F. Molecular genetics of autosomal recessive
polycystic kidney disease. The 2nd International congress of Iranian Society of Pediatric
Nephrology, Mashhad, Iran, 2011.
M.R. Abbaszadegan Page 26 of 26
28. Arabi A, Meysam Moghbeli M, Maleknejad M, Abbaszadegan MR. Mutational Analysis of
Uroporphyrinogen III Synthase Gene in Iranian Families with Congenital Erythropoietic
Porphyria. Medical Genetic Congress 2011. Tehran, Iran, 2011.
29. Abbaszadegan MR, Saidi R, Moaven O, A'rabi, Homaei- Shandiz F, Gholamin M,
Noferesti GH. Sequential Familial Esophageal Squamous Cell Carcinoma and Breast cancer
in several Pedigrees with BRCA2 Mutations. Medical Genetic Congress 2011. Tehran, Iran,
2011.
30. Abbaszadegan MR, Saidi R, Moaven O, A'rabi A, Homaei- Shandiz F, Noferesti GH.
Familial Esophageal Squamous Cell Carcinoma and Breast cancer in several Pedigrees with
BRCA2 Mutations. European Human Genetics Conference 2011. Amsterdam RAI, the
Netherlands, 2011.
31. Forghanifard MM, Gholamin M, Abbaszadegan MR. In silico and ex vivo analysis of two
chimeric polytope constructs for applications in dendritic cell-based cancer immuno-
genetherapy. European Human Genetics Conference 2011. Amsterdam RAI, the
Netherlands, 2011.
32. Dadkhah E, Naseh H, Farshchian M, Memar B, Sankian M, Bagheri R, Forghanifard MM,
Abbaszadegan MR. New Biomarkers Detected for Esophageal Squamous Cell Carcinoma
using Chemiluminescent cDNA Microarray Gene Expression Profiling. European Human
Genetics Conference 2011. Amsterdam RAI, the Netherlands, 2011.
33. Moghbeli M, A'rabi A, Maleknejad M, Abbaszadegan MR. Mutational Analysis of
Uroporphyrinogen III Synthase Gene in Iranian Families with Congenital Erythropoietic
Porphyria. European Human Genetics Conference. Amsterdam RAI, the Netherlands, 2011.
34. Birjandinejad A, Abbaszadegan MR, Bagheri F, Taraz Jamshidi M, Mousavian A. Familial
osteoarthritis hip by acetabular dysplasia.1st International Congress on Hip Dysplasia, from
newborn to elderly, Mashhad, Iran, 2011.
35. Abbaszadegan MR. State-of-the-art cell-based cancer gene therapies: dendritic cell
vaccines. Iranian Congress on Biology and Applications of Stem Cells. Mashhad, Iran,
2011.
36. Abbaszadegan MR, Gholamin M, Forghanifard MM, Moaven O, Farshchian M, Memar B,
Forghani MN, Dendritic cell-based vaccine in cancer: Total RNA Vs Cancer Testis
Chimeric Antigens RNA in Esophageal Squamous Cell Carcinoma.1st annual scientific
meeting of middle- eastern association for cancer research. Tanta- Egypt, 27-29 Dec 2011.
37. Abbaszadegan MR. Ahadian M, keify F.Molecular genetics of autosomal recessive of
polycystic kidney disease.The 2th international congress of Iranian society of pediatric
nephrology. Mashhad, Iran, 2011.
38. Gholamin M, Moaven O, Farshchian M, Mahmoudi M, Sankian M, Memar B, Rajabi-
Mashhadi MT, Forghani MN, Malekzadeh R, Rajabi-Mashhadi MT, Abbaszadegan MR.
M.R. Abbaszadegan Page 27 of 26
Application of RNA molecule in cancer immunotherapy. Cancer Symposium. Mashhad,
Iran, 2010.
39. Abbaszadegan MR. Hereditary cancers. Cancer Symposium. Mashhad, Iran, 2010.
40. Dadkhah E, Farshchian M, Sankian M, Memar B, Naseh H, Forghani M, Kazemi M,
Abbaszadegan MR. Biomarker detection for Esophageal Squamous Cell Carcinoma using
chemiluminescent cDNA Microarray. Cancer Symposium. Mashhad, Iran, 2010.
41. Forghanifard MM, Farshchian M, Gholamin M, Forghani M, Raeisossadati R, Memar B,
Moaven O, Dadkhah E, Moghbeli M, Abbaszadegan MR. Impact of cancer/testis antigens
crosstalk with the major cell signaling pathways on esophageal squamous cell carcinoma.
Cancer Symposium. Mashhad, Iran, 2010.
42. Ghahraman M, Gholamin M, Me'mar B, Forghani MN, Abbaszadegan MR. Establishment
and Characterization of Esophageal Squamous Cell Carcinoma (ESCC) Cell Line from a
high-incidence area in Iran. Cancer Symposium. Mashhad, Iran, 2010.
43. Farshchian M, Yaghoubi V, Forghanifard MM, Naseh H, Raeisossadati R, Dadkhah E,
Forghani MN, Moghbeli M, Abbaszadegan MR. Gene expression analysis by Real-Time
PCR and PCR-Array technology shed light on pobable new roles of pygo2 in carcinogenesis
pathway of esophageal squamous cell carcinoma. Epigenetics and stem cell conference.
Copenhagen, Denmark, 2010.
44. Farshchian M, Yaghoubi V, Forghanifard MM, Naseh H, Raeisossadati R, Dadkhah E,
Forghani MN, Moghbeli M, Abbaszadegan MR. PYGO-2: A downstraem WNT signaling
component overexpression in esophageal squamous cell carcinoma. 11th Iranian Genetics
Congress, Tehran, Iran, 2010.
45. A'rabi A, Hassani S, Vakili R, Saberi MR, Baradaran-Heravi A, Hashemipour M, Razzaghi-
Azar M, Ahadian M, Keify F, Abbaszadegan MR. Prenatal Diagnosis in Families with 11-
Beta Hydroxylase Deficiency Leads Novel Mutations in Two Patients and their Parents.
11th Iranian Genetics Congress, Tehran, Iran, 2010.
46. Ghahraman M, Abbaszadegan MR, Ghaemi N, Noroozi S, Faraji B, Vakili R. A novel
mutation in the SLC19A2 gene in Iranian families with thiamine responsive megaloblastic
anemia, diabetes and deafness syndrome. 11th Iranian Genetics Congress, Tehran, Iran,
2010.
M.R. Abbaszadegan Page 28 of 26
47. Alizade Nakhayi M, Dadkhah E, Abbaszadegan MR. Heterozygosity analysis of four STR
loci from US Combined DNA Index System in a population of Khorasan province. 11th
Iranian Genetics Congress, Tehran, Iran, 2010.
48. Chavoshi S, Dadkhah E, Tavallaie M, Farshchian M, Raeissossadati R, Velayati A, Toliat
kashani M, Ganji A, Jangjoo A, Abbaszadegan MR. Quantitative analysis of Guanylyl
Cyclase c as a tumor marker, validates this marker for early detection of circulating tumor
cells in the peripheral blood of colorectal cancer patients. 11th Iranian Genetics Congress,
Tehran, Iran, 2010.
49. Raeissossadati R, Velayati A, Dadkhah E, Farshchian M, Chavoshi S, Tavassoli A, Mehrabi
Bahar M, Rajabi Mashhadi MT, Abbaszadegan MR. Absolute quantification of tumor
endothelial marker 8 in the peripheral blood of colorectal cancer patients with real-time RT-
PCR. 11th Iranian Genetics Congress, Tehran, Iran, 2010.
50. Forghanifard MM, Farshchian M, Gholamin M, Naseh H, Memar B, Rajabi Mashhadi MT,
Abbaszadegan MR. Comparative analysis of Cancer/testis antigens expression profile in
esophageal squamous cell carcinoma patients using 5’-nuclease assay in real-time PCR. 11th
Iranian Genetics Congress, Tehran, Iran, 2010.
51. Dadkhah E, Memar B, Naseh H, Sankian H, Farshchian M, Bagheri R, Ahmadi S, Moaven
O, Abbaszadegan MR: Microarray Gene Expression Profiling in Esophageal Squamous
Cell Carcinoma, the First Report from Iran. 11th Iranian Genetics Congress, Tehran, Iran, ,
2010 .
52. Abbaszadegan MR, Hassani S, Vakili R, Saberi MR, Baradaran-Heravi AR, A'rabi A,
Hashemipour M, Razzaghi_Azar M, Baratian A: Novel Mutations in CYP11B1 Gene and its
protein modeling in a Patient with 11β-Hydroxylase Deficiency in Iran. 59th Annual Meeting
of American Society of Human Genetics, Hawaii, 2009.
53. Abbaszadegan MR, Moaven O, Sima HR, Ghaffarzadegan K, Forghani MN, A'rabi A,
Raziee HR: A useful serum marker for early detection of gastric cancer, Aberrant p16
methylation. An AACR special conference in cancer research: Candidate pathways, whole
genome scans: Reconciling results, looking into the future, Carefree, Arizona, USA, 2008.
54. Abbaszadegan MR, Hassani S, Baradaran-heravi A, Vakili R, Arabi A, Razzaghi-azar M.
Novel mutation in CYP11B1 gene in a patient with 11- βhydroxylase deficiency in Iran. The
First International Congress on Health Genomics and Biotechnology, Tehran, Iran, 2007.
55. Abbaszadegan MR, Rastin F, Dadkhah E, Lotfalizadeh M. Microsatellite instability in
young Iranian women with endometrioid type endometrial cancer. The First International
Congress on Health Genomics and Biotechnology, Tehran, Iran, 2007.
56. Abbaszadegan MR, Baradaran Heravi A, Vakili R, Gholamin M, Ghaemi N: Three novel
CYP21A2 mutations and their protein modeling in patients with classical 21-hydroxylase
M.R. Abbaszadegan Page 29 of 26
deficiency from northeastern Iran. 3rd Annual Metabolic Diseases World Summit, San
Diego, CA, USA, 2007.
57. Abbaszadegan MR, Raziee HR, Afsharnejad S, Ghaffarzadegan K, Ghavamnasiri MR.
Aberrant p16 Methylation, a possible predisposing factor in familial esophageal squamous
cell carcinoma. 95th Annual meeting of American Association for Cancer Research,
Orlando, Fl, 2004.
58. Abbaszadegan MR, Heidari N, Pazuki N, Jami-Ahamadi K: Mitochondria DNA Alteration
in Gastric Cancer. The First Scientific Meeting of Asian Society for Meitochondrial
Research and Medicine. Seoul, Korea, February 2003.
Invited Presentations and Workshops; Selected few:
Abbaszadegan MR, Tavasoli A, Velayati A, Sima HR, Vosooghinia H, Farzadnia M,
Asadzedeh H, Gholamin M, Dadkhah E, Aarabi A. Stool-based DNA testing, a new
noninvasive method for colorectal cancer screening, the first report from Iran. The King
Hussein Cancer & Biotechnology Institute, The National Cancer Institute of the US, and
Duke University, Middle East and North Africa Cancer Research Conference, Amman,
Jordan, 3 – 4 Sept, 2007.
Abbaszadegan MR. Molecular Genetics & Epigenetic in upper G.I. Cancers. Advance
Molecular Genetics Course, Tehran, Iran, June 10-12, 2006.
Abbaszadegan MR. Molecular genetics and epigenetics in upper GI cancers. The first
Esophageal Cardia Cancer Summit, Scientific sponsors: ISMO, DDRC, IAGH, Iran &
IARC, France, Tehran, Iran, Dec. 13-14, 2005.
Abbaszadegan MR, Scientific Chair, Workshop: Bioinformatics, Webinar to MUMS, 2010.
Abbaszadegan MR, Scientific Chair, Workshop: Diagnostic techniques in Human
Genetics, MUMS, 2009.
Abbaszadegan MR, Scientific Chair, Workshop: Cloning in Eukaryotic Cells, MUMS,
2009.
STUDENTS AND POST DOCS ADVISED
M.Sc. Awarded:
Morshedi-Rad D. (in progress), Zargari F. (in progress), Mollaie F. 2017, Taghehchian N.
2016, Forouzanfar N. 2015, Fardi E. 2015, Khalilipour N. 2016, Hamidi A.2016, Sharifi S.
2015, Tafazzoli A 2014, Nasiri Aghdam M. 2014, Azaraz Sh. 2014, Mahmoudian R. 2013,
Ardalan S. 2013, Pirhoushyaran M. 2012, Taleb S. 2012, Moradi F. 2012, Raad A. 2012,
Torkamandi S. 2012, Raeissosadat R. 2010, Chavoshi S. 2010, Maleki M. 2010, Dadkhah E.
2009, Moghbeli M. 2009, Nakhaee M. 2009, Abrishami T. 2009, Razavipour E. 2009,
Sardari S. 2008, Emami Vahid E. 2006, Khatami F. 2006, Jafarzadeh N. 2006, Afsharnezhad
S. 2005, Pazuki N. 2004, Tohidi F. 2003, Khoshru M. 2002, Gholamin M. 2001,
M.R. Abbaszadegan Page 30 of 26
Ph.D. Awarded:
Reyhaneh Mahmoudian (in progress), Sima Ardalan (in progress), Mahya shariat Razavi (in
progress), Fatemeh Rafinia (in progress), Keyvani V (in progress), Vahid Bagheri 2017,
Meysam Moghbeli 2016, Mohammad Mahdi ForghaniFard 2011, Mehran Gholamin 2008
M.D. Final Thesis:
Oliazadeh P. (in progress), Zeinalzadeh M 2015, Sorouri A 2014, Soltani Delgosha M 2012,
Saeedi R 2012, Nooraee R 2012, Naghibzadeh B 2011, Moaven O 2007, Hassani S 2007,
Baradaran-Heravi AR 2004, Fatehi B 2004, Khameneh-Bagheri A 2001, Farid-hosseini F
2001, Sorouri-Kharashad J 2000.
Residency Final Thesis:
Mousavi L. (OB/Gyn Resident, in progress), Barabadian S. 2014, Abadian MB (Resident
Dermatology) 2009, Dehghan Menshadi H (Resident Pediatric) 2013, Shirkani A (Fellow-
allergy and clinical Immunology) 2013,Broumand S(Resident- Pthology) 2013, Daliri M
(Resident Surgery) 2013, Zand Karimi MR (Fellow- allergy and clinical Immunology) 2012,
Boostani HR (Resident-Periodental) 2011, Manzari F (Resident-Pathology) 2010, Naseh H.
(Resident-Pathology) 2010, Abadian M. (Resident-Dermatology) 2008, Badiei R. (Resident-
Syrgery) 2007, Rastin F. (Resident-OBGyn) 2007, Sarafraz F. (Fellow-OBGyn) 2006,
Post-Docs:
Mazloum Khorasani Z. (Endocrinology- in progress), Velayati A. (fellow-Neurology) 2009,
Razaei Babak A. (Resident-dentistry) 2005, Raziei HR (Resident- Oncology) 2005,
Niazi A. (Resident – Pathology) 2003, Zahidi MR. (Resident – Pathology) 2003,
Talasaz Firoozi E. (Pharm D-final thesis) 2000.