CURRICULUM VITAE Dr. Michael J. Soares · CURRICULUM VITAE Dr. Michael J. Soares Personal...

Soares – September 2008

CURRICULUM VITAE

Dr. Michael J. Soares

Personal Information

Born: November 26, 1954; Chico, California

Marital Status: Married (Marlene Marie) and one child (Jared Thomas)

Present position: University Distinguished Professor Director of the Institute of Maternal-Fetal BiologyVice Chair for Research and DirectorDivision of Cancer & Developmental BiologyDepartment of Pathology & Laboratory Medicine

Work Address: Institute of Maternal-Fetal BiologyUniversity of Kansas Medical Center39th and Rainbow BoulevardKansas City, KS 66160

Telephone numbers: (913) 588-5691 (office); (913) 588-5774 (administrative office); (913) 588-5690 (laboratory)

Fax number: (913) 588-8287

Electronic mail: [email protected]

For appointments and assistance, contact: Stacy McClure, B.A.Senior Coordinator(913) [email protected]

Education

B.A. 1976 Psychology California State University, ChicoUndergraduate advisors: Dr. Michael J. Erpino

Dr. William D. Kalberer (deceased)

Ph.D. 1981 Reproductive Biology University of Hawaii, HonoluluDissertation advisor: Dr. Joan C. Hoffmann

Postdoctoral training:

1981-83 Molecular Endocrinology University of California, Santa CruzAdvisor: Dr. Frank Talamantes

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mailto:[email protected]

mailto:[email protected]


1983-84 Developmental and Cell Baylor College of Medicine, HoustonBiologyAdvisor: Dr. Stanley R. Glasser

Academic Positions

August 1984 to 1989 - Assistant ProfessorDepartment of PhysiologyThe University of Kansas Medical Center

July 1, 1989 to 1993 - Associate Professor with tenureDepartment of PhysiologyThe University of Kansas Medical Center

July 1, 1993 to 2004 - ProfessorDepartment of Molecular & Integrative PhysiologyThe University of Kansas Medical Center

August, 1984 to present - Member of the Mental Retardation and Human Development Research Center; The University of Kansas Medical Center

October, 1992 to present - Member of the Center for Reproduction SciencesThe University of Kansas Medical Center

August, 2002 to present - ProfessorDepartment of Obstetrics & Gynecology, The University of Kansas Medical Center

August, 2002 to present - Director Institute of Maternal-Fetal BiologyThe University of Kansas Medical Center

July, 2004 to present - Professor and DirectorDivision of Cancer & Developmental BiologyDepartment of Pathology & Laboratory MedicineThe University of Kansas Medical Center

September 2005 to present - Program DirectorKansas BIRCWH Faculty Development Program in Women’s Health Research

July 2006 to present - Vice Chair for ResearchDepartment of Pathology & Laboratory Medicine

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The University of Kansas Medical Center

January 1, 2007 to present - University Distinguished ProfessorThe University of Kansas Medical Center

Committees

KUMC, Graduate School five-year review of the Department of Anatomy graduate program,Spring, 1986.

KUMC, Department of Physiology graduate student advisory committee, June, 1987, 1996.

KUMC, Aging Center grant review committee, Fall, 1987.

KUMC, Medical School Admissions Committee, 1988, 1990, 1991.

KUMC, Medical School Research Committee, July 1, 1988, through June 30, 1991.

Ralph L. Smith Mental Retardation Research Center Advisory Committee, 1988-1989.

KUMC, Dissertation committees for: Carla Green (Biochemistry), Sandy Elliott (Physiology), Cathy Sagrillo (Physiology), G. Lian (Anatomy), X. Zhang (Anatomy), S. Xiao (Biochemistry), S. Shang (Biochemistry), Jean Hiebert (Physiology), Karen Kover (Physiology), Xiao-ning Wang (Physiology), Rebecca J. Flietstra (Physiology), Danhua Wang (Anatomy), Wenjiang Chu (Anatomy), Jeremy Chien (Physiology) Gerald Call (Physiology), Peter Opdam (Pharmacology), Tim Burnett (Anatomy & Cell Biology), Theingi Thway (Physiology), Wen-Bin Tsai (Anatomy & Cell Biology), Ryan Gill (Pathology), Erik Rytting (Pharmaceutical Chemistry, University of Kansas-Lawrence), Kara Wagoner (Physiology), Amber Young (Pharmaceutical Chemistry, University of Kansas-Lawrence), Elizabeth Taglauer (Anatomy & Cell Biology), Pallabi Mitra (Pharmaceutical Chemistry, University of Kansas-Lawrence), Sara Turk (Molecular & Integrative Physiology), David Scoville (Pathology & Laboratory Medicine); Emily McDonald (Molecular & Integrative Physiology).

KUMC, Institutional Animal Care and Use Committee, 1991 to 1994.

KUMC, Biological Lecture Series Seminar Program Committee June 1991 to 1996.

KUMC, Advisory Committee for the Center for Reproduction Research, October, 1992 to 1995.

KUMC, Search Committee for the Chairman of the Department of Physiology, 1992 to1993.

Advisory Committee for the KUMC Hispanic Center of Excellence, 1993 to 1994.

KUMC, Department of Physiology Search Committee for Molecular/Reproductive Biologist,

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October 1993 to March 1994

KUMC, Search Committee for the Hall Distinguished Professor in Molecular Medicine, February, 1994 to 1995

KUMC, Radiation Safety Committee, 1994 to 1996.

KUMC, Basic Sciences Graduate Student Core Curriculum and Interdisciplinary ProgramCommittee, September 1994 to July 1995.

KUMC, Advisory committee for the University of Kansas Medical Center Mental Retardation and Human Development Research Center, January, 1995 to 1998

KUMC, Department of Physiology, Chair of Search Committee for an Assistant Professor in thearea of "Signal Transduction in Reproduction and Cancer", April, 1996 to October, 1996

KUMC, Interdisciplinary Graduate Program Advisory Committee, 1996 to 1998

KUMC, Kansas Health Foundation Scholar Program in Cancer Research Steering Committee,July 1996 to 1999

KUMC, Department of Physiology, Promotion and Tenure Committee, September 1996 to 1998, 2001- 2003.

KUMC, Department of Physiology, Chair of Faculty Retreat Organizing Committee, September1996 to November 1996

KUMC, Director, NIH Supported Reproductive Biology Training Program, The University of Kansas Medical Center, September 1996 to 2000.

KUMC, Search Committee for Chair of the Department of Pediatrics, 1996 to 1997

KUMC, Department of Physiology, Chair of Search Committee for an Assistant Professor in thearea of “Developmental Genetics/Gene Targeting”, May 1997 to May 1998

KUMC, School of Medicine Research Task Force Committee, July 1997 to December 1997

KUMC, Director, Center for Reproductive Sciences DNA Sequencing Core, 1997 to 2000.

KUMC, Department of Physiology, Search Committee for an Assistant Professor in the area of“Prostate Biology”, May 1999 to January 2000

KUMC, Associate Director, University of Kansas Medical Center Training Program inBiomedical Research, July 1999 to December 2002

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KUMC, Laboratory Animal Resources Policy and Advisory committee, October 2000 to September 2001

KUMC, Division of Urologic Surgery, Search Committee for a Research Assistant Professor in the area of “Prostate Biology”, August 2001 to December 2001.

Kansas Cancer Institute Leadership Council, January 2002 to January 2003.

KUMC, Search Committee for the recruitment of the Hall Family Endowed Professorship, August 2002 to December 2003.

KUMC, School of Medicine Research Advisory Committee, November 2002 to present.

KUMC, Institute of Maternal-Fetal Biology and the Department of Pathology & Laboratory Medicine, Chair of a faculty search committee for a faculty member in the field of Developmental Biology, July 2003 to May 2004.

KUMC, Department of Pathology & Laboratory Medicine, Promotion and Tenure Committee, September 2003 to present.

KUMC, Transgenic Core Laboratory Oversight Committee, July, 2004 to July 2005, 2006 to present.

KUMC, Institute of Maternal-Fetal Biology and the Department of Pathology & Laboratory Medicine, Chair of a faculty search committee for a faculty member in the field of Mouse Developmental Genetics, August 2004 to June 2005.

KUMC Research Institute Technology Transfer Advisory Committee, June 2005 to present.

KUMC Intercampus Liason Committee, 2005 to 2007.

KUMC, Department of Molecular & Integrative Physiology, Member of a faculty search committee for a Cancer Biologist, August 2005 to May 2006.

KUMC, Institute of Maternal-Fetal Biology and the Department of Pathology & Laboratory Medicine, Chair of a faculty search committee for a faculty member in the field of Transcription/Chromatin Biology.

KUMC, Department of Pathology & Laboratory Medicine, Kansas Cancer Research Institute, and the BIRCWH Program, Chair of a faculty search committee for a faculty member in the field of Breast Cancer Research, August 2007 to January 2008.

KUMC, M.D./Ph.D. Admissions Committee, August 2008 to present.

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Meetings Organized and Consulting

Member of the program committee for a symposium in honor of Dr. Howard A. Bern, entitled: "Cellular signals controlling uterine function", Wichita, Kansas, September, 1989.

Organizer of a Serono Symposia USA sponsored symposium entitled: "Trophoblast cells: Pathways for Maternal-Embryonic Communication", Las Vegas, Nevada, August 6-9th, 1992.

Member of the organizing committee for an international symposium entitled: "The Maternal-Placental-Fetal Dialogue", Maui, Hawaii, February, 1996

Member of the program committee for the Annual Meeting of the Society for the Study of Reproduction, Portland Oregon, July 1996-97

Consultant for the Division of Reproduction, National Institute of Animal Industry, Tsukuba Science City, Japan, November 1996 to 2003

Member of the program committee for the Annual Meeting of the Society for the Study of Reproduction, College Station, Texas, July 1997-98

Member of the organizing committee for the 4th International Federation of Placental Associations meeting, Tokyo, Japan, October 1998

Member of the program committee for the Annual Meeting of the Society for the Study of Reproduction, Madison, Wisconsin, July 1999-2000

Member of the program committee for the Annual Meeting of the Society for the Study of Reproduction, Ottawa, Canada, July 2000-2001

Member of the program committee for the Annual Meeting of the Society for the Study of Reproduction, Baltimore, MD, July 2001-2002

Consultant for the Perinatal Research Center, Department of Pediatrics, University of Colorado Health Sciences Center, Aurora, CO, on a research project entitled: “Fetoplacental amino acid metabolism in IUGR pregnancies”, July 2002-June 2007

Organizer of an American Physiological Society sponsored symposium entitled: "The Maternal-Fetal Dialogue”, Washington, D.C., April 17-21st, 2004

Member of the International Scientific Committee for the Placenta Association of Americas Meeting, Asilomar, California, 2004

Chair, Organizing Committee for the Annual Gilbert S. Greenwald Symposium in Reproductive Biology, Kansas City, Missouri, December 2006 to October 2007.

Consultant for the Center of Biomedical Research Excellence for Perinatal Biology, Brown

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University, Providence, Rhode Island, June 2007 to present

Examiner, Doctor of Philosophy Thesis, The University of Adelaide, Australia, 2008.

Teaching Experience

Endocrinology sections of the Medical Physiology course and a graduate level physiology coursefor allied health students, 1985 to 2004.

Course coordinator for a team-taught graduate level physiology course for allied health students,1989-1992.

Participation in team-taught courses in Reproductive Physiology, Endocrinology, Developmental Biology, Cell Physiology, Stem Cell Biology, Signal Transduction, and Grant Writing, 1985 to present.

Faculty coordinator for the University of Kansas Medical Center Minority Access to ResearchCareers Summer Research Training Program, 1986-1989.

Coordinator of KUMC Reproductive and Developmental Biology Seminar program, 1987 to1992.

Course coordinator for a team-taught graduate level Reproductive Physiology course, 1993 to1998

Honorary Societies and Awards

Phi Kappa Phi Honors Society, California State University, ChicoAchievement Rewards for College Scientists Scholarship, 1980-81National Research Service Award Postdoctoral Fellowship, 1982-84University of Kansas School of Medicine Faculty Research Award, 1989Griff T. Ross Award from the Endocrine Society (for an outstanding abstract/poster in the area of

reproductive physiology), 1990Distinguished Visiting Scientist, University of Tokyo, Tokyo, Japan, 1994Adriana & Luisa Castellucci Award (Recognition for outstanding achievement in placenta

research), 1995Chancellor’s Club Research Award, University of Kansas, 2001Gabriel Bialy Lecture in Reproductive Biology, Southern Illinois University, 2004Dolph C. Simons, Sr., Research Award in the Biomedical Sciences, Higuchi Research

Achievement Award, University of Kansas, 2004University Distinguished Professor, University of Kansas, January 1, 2007 to present

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Professional Societies

American Physiological Society

The Endocrine Society:Professional service: Editorial Board of Endocrinology, 1998 to 2002; Membership Committee, June, 1998 to 2001

Society for the Study of Reproduction:Professional service: Editorial Board of Biology of Reproduction, 1990-1995; Annual Meeting Program Committee, 1996-1998; 1999-2000, 2000-2001, 2001-2002; 2005-2006Publication Committee, 2001-2002Strategic Planning Subcommittee, 2003Nominating Committee, 2005-2006Board of Reviewing Editors for Biology of Reproduction (2005 to present)

International Society for Stem Cell Research

Research Interests

Our laboratory is interested in the regulation of cell differentiation, especially as related to trophoblast stem cells, and signaling pathways controlling their developmental fate. We are also interested in species-specific reproductive adaptations to physiological stressors and signaling events involved in the establishment and maintenance of pregnancy; including investigations on the prolactin gene family, intrauterine inflammatory and immune cells, uterine vasculature, decidual cells, and the invasive trophoblast cell lineage. Invited Lectures

“Some aspects of the control of placental lactogen secretion in the mouse”,Endocrinology Group, Department of Zoology, University of California, Berkeley, California, March, 1982.

“Placental lactogens: developmental landmarks for trophoblast giant cell differentiation in the mouse and rat”, Department of Anatomy, University of California, Davis School of Medicine, Davis, California, November, 1983.

“Comparative biology of placental lactogens”, Department of Developmental andCell Biology, University of California, Irvine, California, January, 1984.

“Placental lactogens and trophoblast giant cell differentiation”, Gordon Research Conference on the Mammalian Genital Tract, Plymouth State College, Plymouth, New Hampshire, July, 1984.

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“Differentiation of rat trophoblast cells in vitro”, Department of Physiology & Biophysics, University of Illinois Medical Center, Chicago, Illinois, October, 1985.

“Growth and differentiation of the rat chorioallantoic placenta”, Reproductive Biology Program, Department of Medicine, McMaster University, Hamilton, Ontario, Canada, April, 1986.

“Cellular and biochemical aspects of placental morphogenesis in the rat”, Department of Structural Biology, University of Missouri, Kansas City, Missouri, December, 1987.

“Trophoblast cell differentiation: expression of the placental prolactin family”, Perinatal Research Institute, Children's Hospital, University of Cincinnati, Cincinnati, January, 1991.

“Cell- and temporal-specific expression of the rat placental prolactin gene family”, Department of Animal Science, University of Tennessee, Knoxville, February, 1991.

“Trophoblast cell endocrine differentiation”, Department of Obstetrics & Gynecology, University of Utah, Salt Lake City, UT, March 1991.

“Trophoblast cell endocrine differentiation: expression of the placental prolactin gene family”, Women's Research Institute, Wichita, Kansas, November, 1991.

“Trophoblast cell differentiation: expression of the placental prolactin gene family”, Department of Obstetrics & Gynecology, Stanford University, Stanford, California, December 1991.

“Trophoblast cell differentiation and the placental prolactin family”, Department of Biology, University of California, Santa Cruz, CA, January, 1992.

“Rat placental prolactin family”, Gordon Research Conference on Prolactin, Oxnard, California, February, 1992.

“Trophoblast cell differentiation: expression of the placental prolactin gene family”, Department of Obstetrics & Gynecology, Washington University, St. Louis, MO, April, 1992.

“Trophoblast cell differentiation”, Gordon Research Conference on Reproductive Tract Biology, Plymouth, New Hampshire, July, 1992.

“Trophoblast cell differentiation: expression of the placental prolactin gene family”, Serono U.S.A. Symposium, Trophoblast cells: Pathways for maternal-embryonic communication. Las Vegas, Nevada, August, 1992.

“Endocrine differentiation of the placenta”, Reproductive Biology Research Center, Department of Cell Biology, Vanderbilt University, Nashville, TN, March, 1993.

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“Trophoblast cell differentiation”, Reproductive Sciences Research Center, Department of Biochemistry, Cell Biology, and Molecular Biology, Northwestern University, Evanston, IL, March, 1994.

“Trophoblast cell differentiation”, Cecil H. and Ida Green Center for Reproductive Biology Sciences, University of Texas, Southwestern Medical Center, Dallas, TX, March 1994.

“The placental and uterine prolactin gene family” and “Control of trophoblast cell differentiation”, Laboratory of Cellular Biochemistry, Veterinary Medical Sciences, The University of Tokyo, Japan, November, 1994.

“Control of trophoblast cell differentiation”, The Sixth Annual Lake Shirakaba Conference on the Biology of Pregnancy, Chino, Japan, November, 1994.

“Trophoblast cell differentiation and expression of the placental prolactin family” Division of Animal Reproduction, National Institute of Animal Industry, Tsukuba City, Japan, November, 1994.

“Control of trophoblast and decidual cell signaling systems”, Department of Obstetrics & Gynecology, Kobe University, Kobe, Japan, November, 1994.

“The extrapituitary prolactin family”, Department of Reproductive and Developmental Toxicology, Shionogi and Co., Ltd., Osaka, Japan, November, 1994.

“Trophoblast cell differentiation: an in vitro model”, Division of Reproductive Biology, Department of Obstetrics & Gynecology, University of Pennsylvania Medical Center, Philadelphia, PA, April, 1995.

“Trophoblast cell differentiation: in vitro models and regulatory circuits”, Fifth Biennial Symposium entitled: The Continuation of Development in the Adult: Regulation of Cell Growth, Death, and Differentiation in the Reproductive System, Center for Studies in Reproduction, University of Maryland, Baltimore, Maryland, June, 1995.

“Trophoblast cells: mediators of maternal-embryonic communication”, Keynote address at the Annual Teratology Society Meeting, Newport Beach California, June 1995

“Trophoblast, decidua, and the prolactin family”, VIth Meeting of the European Placenta Group Joint Meeting with the Rochester Trophoblast Conference, Spa, Belgium, September, 1995.

“Trophoblast cell differentiation and the placental prolactin gene family”, Department of Biology, University of Texas-San Antonio, December, 1995

“Differentiation of trophoblast endocrine cells”, The Maternal-Placental-Fetal Dialogue, an

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International Workshop sponsored by the Science and Technology of Japan. Maui, Hawaii, February, 1996

“Molecular mechanisms of placental development”, 39th Nestle Nutrition Workshop, Sussex, England, May, 1996

“Molecular mechanisms of placental development”, Royal College of Physicians, London, England, May, 1996

“Trophoblast cell differentiation: acquisition of endocrine activities”, Rochester Trophoblast Conference, Banff, Alberta, Canada, September 1996

“Placental prolactin family and pregnancy”, President's Symposium, at the 1997 Annual Meeting of the Society for the Study of Reproduction, Portland, OR, August, 1997

“Molecular mechanisms of placental development” and “The prolactin gene family and pregnancy”, 8th Annual Colorado Clinical Scholars Program, Aspen CO, September, 1997

“The uteroplacental prolactin family”, Regeneron Pharmaceuticals, Tarrytown, NY, Feb, 1998

“The uteroplacental prolactin family: signals for the establishment and maintenance of pregnancy”, Department of Molecular Biology, University of Missouri, Kansas City, MO, March 1998

“Differentiation of trophoblast endocrine cells”, Symposium title: Developmental Biology of Endocrine Systems, 80th Annual Meeting of the Endocrine Society, New Orleans, LA, June 1998

“Uteroplacental signals in the establishment of pregnancy”, International Workshop on Embryogenesis and Implantation, Hawaii, Hawaii, February 1999

“The uteroplacental prolactin family: activators of signaling pathways ensuring viviparity”, Arbeitskreis Molekularbiologie in der Frauenheikunde (AMF) Workshop, Rostock, Germany, June 1999

“Novel uteroplacental cytokines regulating immune cells: the prolactin family”, Institute of Medical Biochemistry and Molecular Biology, University of Rostock, Rostock, Germany, June 1999

“Uteroplacental signals in the establishment of pregnancy”, Department of Physiology, Colorado State University, Fort Collins, CO, September, 1999

“Uteroplacental prolactin family and pregnancy”, Department of Obstetrics & Gynecology, Washington University School of Medicine, St. Louis, MO, January, 2000

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“Uteroplacental prolactin family: immunological regulators of viviparity?”, Gordon Research Conference on Prolactin, Ventura, California, February, 2000

“The uteroplacental prolactin family: a determinant of viviparity?”, Reproductive Biology Program, Univeristy of Texas-Houston, March, 2000

“The prolactin family and pregnancy”, London Regional Cancer Center, University of Western Ontario, London, Canada, September, 2000

“The prolactin family and pregnancy”, Reproductive Biology Group, Texas A&M University, College Station, TX, March, 2001

“Placental hormones and targeting of natural killer cells”, European Placental Group, Sorrento, Italy, September, 2001

“The placenta and the prolactin family”, 4th Symposium for Regeneration and Tissue Engineering Technology in Placenta, Tokyo, Japan, November, 2001

“Biology of viviparity: the placenta and the prolactin family”, Department of Obstetrics & Gynecology, University of Colorado, Denver, CO, November, 2001

“The prolactin family and pregnancy”, Frontiers in Reproduction Fifth Annual Symposium: Immune Mechanisms in Pregnancy, Boston, MA, June, 2002

“The prolactin family and pregnancy”, Children’s Mercy Hospital, Kansas City, Missouri, November, 2002

“Biology at the maternal-fetal interface: the prolactin gene family expansion”, Department of Physiology, Wright State University, Ohio, November, 2002

“The prolactin family expansion and pregnancy”, Reproductive Biology Program, University of Kentucky, Lexington, Kentucky, May 2003

“The prolactin family and pregnancy”, International Conference on the Female Reproductive Tract, Frauenchiemse, Germany, June, 2003

“Maternal-fetal interface, trophoblast invasion, and pregnancy-specific cytokines”, NIDA Sponsored Workshop on Placental Proteins, Drug Transport, and Fetal and Perinatal Development”, Bethesda, Maryland, August, 2003

“Maternal-fetal interface and pregnancy-specific cytokines”, Reproductive Biology Program, University of Missouri, Columbia, December, 2003.

“Prolactin family expansion and the maternal-fetal interface”, American Physiological Society

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Symposium on the Maternal-Fetal Dialogue, Washington D.C., April, 2004

“Prolactin family expansion and the maternal-fetal interface”, Gabriel Bialy Lecture in Reproductive Biology, Southern Illinois University School of Medicine, April, 2004

“Invasive trophoblast cells: what we can learn from rodents?”, Presidential Symposium, American Society Reproductive Immunology, St. Louis, MO, June 2004

“Gestation stage dependent interactions between trophoblast cells and natural killer cells”, Mini-Symposium on Reproductive Immunology, Annual Meeting for the Society for the Study of Reproduction, Vancouver, British Columbia, Canada, August, 2004

“Prolactin family and pregnancy-dependent adaptations”, Cooperative Reproductive Science Research Center, Morehouse School of Medicine, Atlanta, Georgia, October 2004

“The prolactin family and adaptations to pregnancy”, Reproductive Biology Group, Brown University, Providence, Rhode Island, December 2005

“The prolactin family and adaptations to pregnancy”, PROLACTIN FAMILY GORDON RESEARCH CONFERENCE, Ventura, California, January 2006

“Prolactin family expansion and pregnancy”, GORDON RESEARCH CONFERENCE ON REPRODUCTIVE SYSTEMS BIOLOGY, Connecticut College, New London, Connecticut, June 2006

“Genetic aspects of pregnancy-dependent adaptations to hypoxia”, THE 12th INTERNATIONAL FEDERATION OF PLACENTAL ASSOCIATIONS MEETING, Kobe, Japan, September 2006

“The prolactin family and pregnancy-dependent adaptations”, JAPANESE SOCIETY OF ANIMAL REPRODUCTION, Nagoya, Japan, September 2006

“The prolactin family and pregnancy-dependent adaptations to hypoxia”, Department of Biological Sciences, University of Delaware, Newark, Delaware, October 2006

“Uteroplacental adaptations to hypoxia”, Department of Obstetrics & Gynecology, Loma Linda University, Loma Linda, California, April 2007

“The prolactin family and pregnancy-dependent adaptations to physiological stressors” Integrated Biomedical Sciences Program, Loma Linda University, Loma Linda, California, April 2007

“Genetic aspects regulating placentation”, Perinatal Research Center, Loma Linda University, Loma Linda, California, April 2007

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“Uteroplacental adaptations”, Seminars on Maternal-Fetal Interactions, University of São Paulo, Brazil, October 2007

“The prolactin family and the maternal-fetal interface”, Seminars on Maternal-Fetal Interactions, University of São Paulo, Brazil, October 2007

“Uteroplacental Adaptations”, Latin American Symposium on Maternal-Fetal Interaction – Placenta, Los Cocos, Argentina, November 2007

“The prolactin family and placentation”, Latin American Symposium on Maternal-Fetal Interaction – Placenta, Los Cocos, Argentina, November 2007

“Uteroplacental adaptations”, NICHD Lecturer, Perinatal Research Society, Santa Fe, New Mexico, September, 2008

Ad hoc reviewer

Biochimica Biophysica ActaBMC Developmental BiologyBMC GenomicsDevelopmentDevelopmental BiologyDevelopmental DynamicsEndocrinologyEuropean Journal of BiochemistryGeneGenesisHuman ReproductionJournal of Biological ChemistryJournal of Clinical Endocrinology & MetabolismJournal of Clinical InvestigationJournal of Reproductive ImmunologyMammalian GenomeMolecular Biology and EvolutionMolecular CarcinogenesisMolecular & Cellular EndocrinologyMolecular & Cellular BiologyMolecular EndocrinologyMolecular PharmaceuticsNature Medicine

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Pediatric ResearchPhysiological GenomicsPlacentaProceedings of the National Academy of Sciences, USAReproduction

Editorial Boards and Editorships:

Biology of Reproduction Editorial Board (1990 to 1995)Board of Reviewing Editors (2005 to present)

Trophoblast Research (1996 to 2000)

Endocrinology (1998 to 2002)

Journal of Endocrinology (2000 to 2005) Editorial Board, Jan 2000-October 2000Senior Editor, October 2000-2005

Reproductive Biology Insights (2008-present)Honorary Editorial Board

National Advisory Panels:

National Institutes of Health: Human Embryology and Development II Study Section (1993 to 1996)

National Institutes of Health: Reproductive Biology Study Section (Ad hoc, 1998)

National Institutes of Health, NICHD, Chair of Program Project Site Visit, (July, 1999)

National Institutes of Health, NICHD, Special Emphasis Panel Review for the Women’s Health Initiative Institutional Faculty Development Awards (April, 2000)

National Institutes of Health, NICHD, Special Study Sections, (October, 2004, July 2005, October 2008)

National Institutes of Health, NICHD, Special Emphasis Panel Review for the Women’s Health Initiative Institutional Faculty Development Awards (March 2007)

Ad hoc Grant Reviews

National Science FoundationUnited States Department of Agriculture

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Medical Research Council of CanadaUnited States-Israel Bi-national Agricultural Research and Development FundAmericas Fellowship Program, 2002, 2003Australian Brewers’ Foundation Medical Research Grant Program, 2004Israel Science Foundation, 2005Wellcome Trust, 2006Science Foundation of Ireland, 2007Austrian Science Fund, 2007

Trainees

Undergraduate students:

Barbara Foster (1985-86)Kathleen D. Schaberg (Summer 1986)Catherine S. Pinal (Summer 1986)Sarvepalli Jokhai (Summer 1987)Gary Podschun (Summer 1987)Michael Chang (Summer 1987)Kendall Boone (1988)H. Philip Owens (Summer 1988)Adam Newman (Summer 1991)Sean Vellucci (Summer 1993, Summer 1995)Richard Heck (Summer 1994)Michael J. Riley (Summer 1994)David Razafsky (Summer 2000)Kerry McGonigle (Summer 2001)My-Linh H. Trinh (2001-2003)Kristin Woo (Summer 2002)Darya Kahlili (Summer 2004)Jessica Lerner (Summer 2005)Naomi Butler (Summer 2008)

Medical students:

Daniel Prohaska (Summer 1992)Sandra Archer (Summer 1999); Recipient of a Summer Research Fellowship from the Endocrine

SocietyRobert Ray (Spring 2007)

Graduate students:

Teresa N. Faria (1987-1991); Recipient of a Fulbright Predoctoral Fellowship; Ph.D. degree awarded August 1991; Present address: Research Scientist, Bristol-Myers Squibb, New

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Brunswick, New Jersey

Xing-jian Lu (July, 1990-1993; M.S. degree awarded May 1993); Present address: Private practice physician, Kansas City area.

Gary P. Hamlin (1991 to 1994); Ph.D. degree awarded October 1994; Present address: Associate Lecturer in Pharmacology/Physiology in the Department of Molecular Sciences, James Cook University of North Queensland, Townsville, Queensland, Australia

Christine A. Rasmussen (1993-1996); Ph.D. degree awarded April 1996; Present address: Legal consultant, Kansas City area.

Thomas J. Peters (1995 to 1998); Recipient of a Kansas Health Foundation Fellowship and the W.S. Sutton Scholarship Award; Ph.D. degree awarded April 1998; Present address: Instructor, St. Louis Community College, St. Louis, Missouri.

Jennifer K. Ho-Chen (2003 to 2007); Recipient of an Individual National Research Service Award Predoctoral Fellowship from the National Institutes of Health, F31 HD045052, $113,936 (direct costs), July 2003, June 2007; Ph.D. degree awarded June 2007.

Lindsey N. Canham (2005 to present) Recipient of a Predoctoral Training Award from the KUMC Biomedical Training Program (2007-2008). Recipient of a Travel Award for the International Federation of Placental Associations Annual Meeting, Kingston, Ontario, 2007.

Damayanti Chakraborty (2007 to present) Recipient of the Poster Award at the 2007 Annual Greenwald Symposium.

Visiting graduate students:

Andrea Bertazolli Albieri (1996); Recipient of a FAPESP fellowship; Present address: Department of Cell Biology, University of Sao Paulo, Brazil.

Postdoctoral Fellows:

Dr. Swapan De (1986-87); Present position: Staff Scientist, Laboratory of Molecular Biology, National Institute of Mental Health, Bethesda, Maryland

Dr. Mamata De (1986-87); Present position: Staff Scientist, Marion Merrell Dow, Inc., Cincinnati, OH

Dr. Kazuyoshi Hashizume (1987-88, 1992); Present position: Professor of Physiology, Iwate University, Moriaka, Japan.

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Dr. Santanu Deb (1987-93); Recipient of a Kansas Health Foundation Fellowship; Present position: Department of Homeland Security, Skokie, Illinois.

Dr. Wendy Jo Campbell (1988-89); Recipient of a Kansas Health Foundation Fellowship; Present position: Streck Laboratories, Inc., Industrial Road, Omaha, Nebraska

Dr. Katherine F. Roby (1990-1992); Recipient of a Kansas Health Foundation Fellowship and an Individual National Research Service Award Postdoctoral Fellowship from the National Institutes of Health; Present position: Research Associate Professor, Department of Anatomy & Cell Biology, University of Kansas Medical Center

Dr. Toshiya Yamamoto (1992-1994); Recipient of a Kansas Health Foundation Fellowship; Present position: Chief, Department of Obstetrics & Gynecology, Sakai Municipal Hospital, Osaka, Japan

Dr. Takayuki Kamei (1993-1996); Present position: Staff Scientist, Takeda Chemical Industries, Osaka, Japan

Dr. Guoli Dai (1994-1998); Present position: Research Assistant Professor, Department of Pharmacology, Toxicology, and Therapeutics, The University of Kansas Medical Center, Kansas City, Kansas

Dr. Kyle E. Orwig (1994-1998); Recipient of a Lalor Foundation Fellowship and a Kansas Health Foundation Fellowship; Present position: Assistant Professor, Department of Obstetrics & Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Magee Women’s Research Institute, Pittsburgh, PA

Dr. Heiner Müller (1995-1997); Recipient of a Fellowship from the Deutsche Forschungsgemeinschaft of Germany; Present position: Associate Professor, Department of Obstetrics & Gynecology, University of Rostock, Rostock, Germany

Dr. Toru Takahashi (1997, 2001-2002); Present position: Staff Scientist, Department of Reproductive Biology and Technology, National Institute of Agrobiological Sciences, Ibaraki, Japan

Dr. Ryuta Ishimura (1997); Recipient of a Fellowship from the Japan Society for the Promotion of Science; Present position: Postdoctoral Associate, Jackson Laboratories, Bar Harbor, Maine.

Dr. Gregory Knipp (1997-1999); Recipient of a Postdoctoral Fellowship from the American Heart Association; Present position: Assistant Professor, Department of Pharmaceutics, Purdue University, West Lafayette, IN

Dr. Danhua Wang (1997-2000); Recipient of a Kansas Health Foundation Fellowship; Present position: Research Scientist, Department of Obstetrics & Gynecology, University of California,

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Los Angeles, CA

Dr. Rupasri Ain (1999-2003); Recipient of a University of Kansas Medical Center Training Program in Biomedical Sciences Postdoctoral Fellowship (1999-2000) and a Postdoctoral Fellowship from the American Heart Association (2000-2002); Present position: Research Scientist, National Centre for Biological Sciences, Bangalore, India.

Dr. Long-jiang Shao (2001-2002); Present position: Research Associate, Department of Obstetrics & Gynecology, Baylor College of Medicine.

Dr. Shigeki Ohboshi (2002-2004) Present position: Assistant Professor, Department of Animal Science, Nippon Veterinary and Animal Science University, 1-7-1 Kyonan, Musashino, Tokyo, Japan.

Dr. Juan A. Arroyo (2003-2004) Present position: Instructor, Department of Obstetrics & Gynecology, University of Colorado Health Sciences Center, Denver, Colorado.

Dr. Juan J. Bustamante (2003-2007) Recipient of a Minority Postdoctoral Training NIH Award, Supplement to HD20676 (2003 to 2007). Present position: Assistant Professor, Department of Pharmaceutical Sciences, Texas A&M University, Kingsville, TX.

Dr. S.M. Khorshed Alam (2003-2006) Recipient of a Postdoctoral Training Award from the KUMC Biomedical Training Program (2004-2005). Recipient of a Lalor Travel Award for the Society for the Study of Reproduction Annual Meeting, Vancouver, British Columbia, 2004. Present position: Senior Research Scientist, Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, Kansas

Dr. Toshihiro Konno (2003-2007) Recipient of a Travel Award for the International Federation of Placental Associations Annual Meeting, Tokyo, Japan, 2006. Present position: Research Assistant Professor, Department of Pathology & Laboratory Medicine, University of Kansas Medical Center, Kansas City, Kansas

Dr. Lea A. Rempel (2005-2007) Recipient of a Postdoctoral Training Award from the KUMC Biomedical Training Program (2005-2006); Recipient of a Travel Award for the International Federation of Placental Associations Annual Meeting, Kingston, Ontario, 2007. Present position: Research Physiologist, U.S. Meat Animal Research Center, Reproduction Research Unit, USDA, Clay Center, Nebraska.

Dr. Gracy X. Rosario (January 2006- April 2008) Recipient of a Postdoctoral Training Award from the KUMC Biomedical Training Program (2006-2007). Recipient of a Travel Award for the International Federation of Placental Associations Annual Meeting, Kingston, Ontario, 2007. Recipient of a Postdoctoral Fellowship from the American Heart Association, AHA Identification Number: 0725751Z, $85,000 (direct costs), July 1, 2007 to June 30, 2009. Present position: Developmental and Regenerative Biology Group, Institute of Medical Biology, Singapore.

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Dr. Mohammad Azharul Karim Rumi (June 2007-July 2008) Present position: Research Assistant Professor, Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, Kansas.

Dr. Dong-Soo Lee (August 2007-present)

Dr. Kazuo Asanoma (September 2007-present)

Current Laboratory Staff

Stacy McClure, Senior CoordinatorDr. Toshihiro Konno, Research Assistant ProfessorDr. Mohammad Azharul Karim Rumi, Research Assistant ProfessorDr. S.M. Khorshed Alam, Senior Research ScientistDr. Dong-Soo Lee, Postdoctoral fellowDr. Kazuo Asanoma, Postdoctoral fellowLindsey N. Canham, Graduate StudentDamayanti Chakraborty, Graduate StudentBrent Canham, Research AssistantAmanda Crowley, Research Assistant

Research Support

National Research Service Award Postdoctoral Fellowship, "Control of Placental Lactogen Secretion", Principal Investigator, Michael J. Soares, $18,468 (direct costs)/year, September 1, 1982, through July 31, 1984.

American Cancer Society Small Grants Program, "Control of Tumorigenic Trophoblast Cells", Principal Investigator, Michael J. Soares, $5,000 (total direct costs), January 1, 1985, through December 31, 1985.

National Institutes of Health, "Trophoblast Differentiation", RO1-HD20676, Principal Investigator, Michael J. Soares, $228,341 (total direct costs), July 1, 1986, through April 30, 1990.

Flossie West Memorial Trust, "Uterine and Hormonal Control of Placental Cell Tumorigenicity", Principal Investigator, Michael J. Soares, $25,000 (total direct costs), January 1, 1987, through December 31, 1987.

National Institutes of Health, "Trophoblast Prolactin-like Proteins", RO1-HD22208, Principal Investigator, Michael J. Soares, $254,469 (total direct costs), May 1, 1987, through April 30, 1990.

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Wesley/Kansas Health Foundation, "A Multidisciplinary Program for Cancer Research and Training", Subgrant to Michael J. Soares, $20,000 (direct costs)/year, July 1, 1988, through June 30, 1996.

National Institutes of Health, "Trophoblast Differentiation", RO1-HD20676, Principal Investigator, Michael J. Soares, $579,059 (total direct costs), May 1, 1990 through April 30, 1995.

National Institutes of Health, "Biology of the Placental Prolactin Family", RO1-HD29036, Principal Investigator, Michael J. Soares, $394,253 (total direct costs), April 1, 1992 through March 31, 1996 (continuation of HD22208).

National Institutes of Health, "Trophoblast Cells", partial support for a conference,HD28954, Principal Investigator, Michael J. Soares, $8,488 (total direct costs), April 1, 1992 through March 30, 1993.

United States Department of Agriculture, "Trophoblast Conference", partial support for a conference, USDA 9202625, Principal Investigator, Michael J. Soares, $6,005 (total direct costs), July 1, 1992 through June 30, 1993.

National Institutes of Health, "Decidual Signals in the Establishment of Pregnancy", RO1-HD29797, Principal Investigator, Michael J. Soares, $551,211 (total direct costs) April 1, 1994 through March 30, 2000.

National Institute of Drug Abuse, "In vitro cell culture model for the placental barrier: transport and metabolism of drugs of abuse", NIDA RFP-NO1DA-4-7405, Principal Investigator, Dr. Kenneth L. Audus of The University of Kansas, Department of Pharmaceutical Chemistry, subcontract to Michael J. Soares, $50,812 (total direct costs), October 1, 1994 through September 30, 1999.

National Institutes of Health, "Trophoblast Differentiation", RO1-HD20676, Principal Investigator, Michael J. Soares, $617,600 (total direct costs), February 1, 1996 through January 31, 2001.

National Institutes of Health, "Reproductive Biology Training Grant", T32 HD07455, Principal Investigator, Michael J. Soares, $268,914 (total direct costs), May 1, 1996 through April 30, 2001.

J.B. Reynolds Foundation, "Biology at the Maternal-Fetal Interface", Principal Investigator, Michael J. Soares , $6,000 (total direct costs), January 1, 1997 through December 31, 2000.

National Institutes of Health, "Pregnancy-specific Modulation of Natural Killer Cells", RO1-HD37123, Principal Investigator, Michael J. Soares, $501,197 (total direct costs), August 1, 1999 through July 30, 2002.

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National Institutes of Health, "Novel Cytokine-Natural Killer Cell Signaling", RO3-HD38430, Principal Investigator, Michael J. Soares, $100,000 (total direct costs), March 1, 2000 through February 28, 2002.

Mellon Foundation, “Maternal Adaptations to Implantation”, Principal Investigators, Michael J. Soares and Guoli Dai, $420,000 (total direct costs), April 1, 2000 through March 31, 2003 [Faculty development award for Dr. Guoli Dai] National Institutes of Health, “Maternal Adaptations to Pregnancy”, RO1-HD40413, Principal Investigator, Michael J. Soares, $180,000 (total direct costs) April 6, 2001 through March 31, 2002. [This project was originally approved for four years. It was terminated early and rolled into PO1-HD39878, see below].

National Institutes of Health, "Trophoblast Differentiation", RO1-HD20676, Principal Investigator, Michael J. Soares, $1,025,000 (total direct costs), May 1, 2002 through April 30, 2007.

National Institutes of Health, “Trophoblast Differentiation-Supplement for Dr. Juan Jose Bustamante”, RO1-HD20676-S1, Principal Investigator, Michael J. Soares, $230,000 (total direct costs), May 1, 2002 through April 30, 2007

National Institutes of Health, “Biology at the Maternal-Fetal Interface”, PO1-HD39878, Principal Investigator, Michael J. Soares, $3,097,300 (total direct costs), April 1, 2002 through March 31, 2007. Dr. Soares is Principal Investigator of Subproject No. I, “Decidual Signals in the Establishment of Pregnancy”, $839,158 (total direct costs) and Director of the “Administrative Core”, $247,941 (total direct costs).

National Institutes of Health, “Trophoblast Differentiation-Supplement for Human Embryonic Stem Cell Research, RO1-HD20676-S2, Principal Investigator, Michael J. Soares, $150,000 (total direct costs), May 1, 2003 through April 30, 2005.

Hall Family Foundation, “Hypoxia and Vascular Programming”, Principal Investigator, Michael J. Soares, $300,000 (total direct costs). September 15, 2003 through September 14, 2005.

National Institutes of Health, “Biology at the Maternal-Fetal Interface-Supplement for Human Embryonic Stem Cell Research”, PO1-HD39878-S1, Principal Investigator, Michael J. Soares, $150,000 (total direct costs), April 1, 2004 through March 31, 2006.

National Institutes of Health, “Regulation of Pregnancy-Dependent Adaptations”, RO1-HD048861, Principal Investigator, Michael J. Soares, $1,012,500 (total direct costs), July 20, 2005 through May 31, 2010.

National Institutes of Health, “BIRCWH Career Development Program in Women’s Health”, K12 HD052027, Principal Investigator, Patricia A. Thomas, Program Director, Michael J. Soares, $2,312,500 (total direct costs), October 1, 2005 through September 30, 2010.

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National Institutes of Health, “Regulation of Pregnancy-Dependent Adaptations-Supplement for Human Embryonic Stem Cell Research”, RO1-HD048861-S1, Principal Investigator, Michael J. Soares, $150,000 (total direct costs), July 20, 2005 through May 31, 2007.

National Institutes of Health, “Physiological Genomics of Pregnancy”, R21-HD049503, Prinicpal Investigator, Michael J. Soares, $228,250 (total direct costs), August 1, 2006 through July 31, 2008.

National Institutes of Health, “Decidual Cell Adaptations to Physiological Stressors”, RO1-HD055523, Principal Investigator, Michael J. Soares, $1,037,500 (total direct costs), April 12, 2007 through March 31, 2012.

National Institutes of Health, “Trophoblast Differentiation”, RO1-HD20676, Principal Investigator, Michael J. Soares, $1,037,500 (total direct costs), May 7, 2007 through April 30, 2012.

National Institutes of Health, “Trophoblast Differentiation”, RO1-HD20676-S1 for the generation of knock-out mice, Principal Investigator, Michael J. Soares, $13,125 (total direct costs), August 1, 2008 through July 31, 2010.

List of Publications (chronological order)

1. Soares, M.J., Kalberer, W.D. and Erpino, M.J. (1977). Progestagen effects on elicitation of aggressive behaviour in male mice. Journal of Endocrinology 73, 507-510.

2. Soares, M.J., Kalberer, W.D. and Erpino, M.J. (1978). Progesterone: effects on investigatory preferences, aggression and olfaction in orchidectomized, testosterone-treated mice. Behavioral Biology 23, 260-266.

3. Soares, M.J. and Chamley, W.A. (1980). A critical time period for the vagino- cervical stimulus to induce immediate pseudopregnancy in the diestrous rat. Australian Journal Biological Sciences 33, 709-712.

4. Soares, M.J. and Hoffmann, J.C. (1981). Seasonal reproduction in the mongoose, Herpestes auropunctatus. I. Androgen, luteinizing hormone, and follicle stimulating hormone in the male. General & Comparative Endocrinology 44, 350-358.

5. Soares, M.J., Colosi, P. and Talamantes, F. (1982). The development and characterization of a homologous radioimmunoassay for mouse placental lactogen. Endocrinology 110, 668-670.

6. Soares, M.J. and Diamond, M. (1982). Pregnancy and chin-marking in the rabbit, Oryctolagus cuniculus. Animal Behavior 30, 941-943.

7. Soares, M.J. and Hoffmann, J.C. (1982). Seasonal reproduction in the mongoose, Herpestes

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auropunctatus. II. Testicular responsiveness to luteinizing hormone. General & Comparative Endocrinology 47, 226-234.

8. Soares, M.J. and Hoffmann, J.C. (1982). Seasonal reproduction in the mongoose, Herpestes auropunctatus. III. Regulation of gonadotropin secretion in the male. General & Comparative Endocrinology 47, 235-242.

9. Soares, M.J. and Hoffmann, J.C. (1982). Melatonin suppression of post- castration serum luteinizing hormone and follicle stimulating hormone responses in the male mongoose, Herpestes auropunctatus. General & Comparative Endocrinology 48, 525-528.

10. Soares, M.J. and Hoffmann, J.C. (1982). Role of daylength in the regulation of reproductive function in the male mongoose, Herpestes auropunctatus. Journal of Experimental Zoology 224, 365-369.

11. Soares, M.J. and Talamantes, F. (1982). Placental and serum hormone changes during the second-half of pregnancy in the hamster. Biology of Reproduction 27, 523-529.

12. Soares, M.J. and Talamantes, F. (1982). Gestational effects on placental and serum androgen, progesterone, and prolactin-like activity in the mouse. Journal of Endocrinology 93, 29-36.

13. Matt, K.S., Soares, M.J., Talamantes, F. and Bartke, A. (1983). Effects of handling and ether anesthesia on serum prolactin levels in the golden hamster. Proceedings of the Society of Experimental Biology & Medicine 173, 463-466.

14. Soares, M.J., Colosi, P., Ogren, L. and Talamantes, F. (1983). Identification and partial characterization of a lactogen from the midpregnant mouse conceptus. Endocrinology 112, 1313-1317.

15. Soares, M.J., Colosi, P. and Talamantes, F. (1983). Development of a homologous radioimmunoassay for secreted hamster prolactin. Proceedings of the Society of Experimental Biology & Medicine 172, 379-381.

16. Soares, M.J. and Talamantes, F. (1983). Genetic and litter size effects on serum placental lactogen in the mouse. Biology of Reproduction 29, 165-171.

17. Soares, M.J. and Talamantes, F. (1983). Midpregnancy elevation of serum androstenedione levels in the C3H/HeN mouse: placental origin. Endocrinology 113, 1408-1412.

18. Steger, R.W., Bartke, A., Goldman, B.D., Soares, M.J. and Talamantes, F. (1983). Effects of short photoperiod on the ability of golden hamster pituitaries to secrete prolactin and gonadotropins in vitro. Biology of Reproduction 29, 872-878.

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19. Bartke, A., Siler-Khodr, T.M., Soares, M.J., Talamantes, F., Goldman, B.D., Hogan, M.P. and Hebert, A. (1984). Does prolactin modify testosterone feedback in the hamster? Pituitary grafts alter the ability of testosterone to suppress LH and FSH release in castrated male hamsters. Endocrinology 115, 1506-1510.

20. Hoffmann, J.C., Soares, M.J., Nelson, M.L. and Cullin, A.M. (1984). Seasonal reproduction in the mongoose, Herpestes auropunctatus. IV. Organ weights and serum hormone levels in the female. General & Comparative Endocrinology 55, 306-314.

21. Matt, K.S., Bartke, A., Soares, M.J. and Talamantes, F. (1984). Does prolactin modify testosterone feedback in the hamster? Suppression of plasma prolactin inhibits photoperiod decreases in testosterone feedback sensitivity. Endocrinology 115, 2098-2103.

22. Soares, M.J., Bartke, A., Colosi, P. and Talamantes, F. (1984). Identification of placental lactogen in pregnant Snell and Ames dwarf mice. Proceedings of the Society for Experimental Biology & Medicine 175, 106-108.

23. Soares, M.J. and Talamantes, F. (1984). Pre-parturitional changes in serum prolactin, placental lactogen, growth hormone, progesterone, and corticosterone in the C3H/HeN mouse. Journal of Developmental Physiology 6, 423-429.

24. Steger, R.W., Bartke, A., Matt, K.S., Soares, M.J. and Talamantes, F. (1984). Neuroendocrine changes in male hamsters following photostimulation. Journal of Experimental Zoology 229, 467-474.

25. Amador, A., Klemcke, H.G., Bartke, A., Soares, M.J., Siler-Khodr, T.M. and Talamantes, F. (1985). Effects of different numbers of ectopic pituitary transplants on regulation of testicular LH/hCG and prolactin receptors in the hamster (Mesocricetus auratus). Journal of Reproduction & Fertility 73, 483-489.

26. Huseby, R.A., Soares, M.J. and Talamantes, F. (1985). Ectopic pituitary grafts in mice: hormone levels, effects on fertility, and the development of adenomyosis uteri, prolactinomas and mammary carcinomas. Endocrinology 116, 1440-1448.

27. Soares, M.J., Julian, J.A. and Glasser, S.R. (1985). Trophoblast giant cell release of placental lactogens: temporal and regional characteristics. Developmental Biology 107, 520-526.

28. Soares, M.J. and Talamantes, F. (1985). Placental lactogen secretion in the mouse: in vitro responses, ovarian and progesterone influences. Journal of Experimental Zoology 234, 97-104.

29. Stallings, M.H., Matt, K.S., Amador, A., Bartke, A., Siler-Khodr, T.M., Soares, M.J. and Talamantes, F. (1985). Regulation of testicular LH/hCG receptors in golden hamsters

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(Mesocricetus auratus) during development. Journal of Reproduction & Fertility 75, 663-670.

30. Glasser, S.R., Julian, J., Munir, M.I. and Soares, M.J. (1987). Biological markers during early pregnancy: trophoblastic signals of the peri-implantation period. Environmental Health Perspectives 74, 129-147.

31. Soares, M.J. and Glasser, S.R. (1987). Placental lactogen production and functional differentiation of rat trophoblast cells in vitro. Journal of Reproduction & Fertility 79, 335-341.

32. Soares, M.J. (1987). Developmental changes in the intraplacental distribution of placental lactogen and alkaline phosphatase in the rat. Journal of Reproduction & Fertility 79, 93-98.

33. Soares, M.J., Schaberg, K.D., Pinal, C.S., De, S.K., Bhatia, P. and Andrews, G.K. (1987). Establishment of a rat placental cell line expressing characteristics of extraembryonic membranes. Developmental Biology 124, 134-144.

34. Campbell, G.T., Wagoner, J., Colosi, P., Soares, M.J. and Talamantes, F. (1988). Development and retention of phenotypically specialized cells in pituitary allografts in the hamster. Cell Tissue Research 251, 215-220.

35. Hunt, J.S. and Soares, M.J. (1988). Expression of histocompatibility antigens, transferrin receptors, intermediate filaments, and alkaline phosphatase by in vitro cultured rat placental cells and rat placental cells in situ. Placenta 9, 159-171.

36. Hunt, J.S., Suzuki, Y., Wood, G.W. and Soares, M.J. (1988). Ultrastructure of cultured rat placental cells. Placenta 9, 147-158.

37. Soares, M.J., De, S.K., Foster, B.A., Julian, J.A. and Glasser, S.R. (1988). Identification of multiple low molecular weight placental lactogens produced by rat trophoblast cells. Journal of Endocrinology 116, 101-106.

38. De, M., Hunt, J.S. and Soares, M.J. (1988). Stimulation of rat placental cell DNA synthesis by transferrin. Biology of Reproduction 38, 1123-1128.

39. Soares, M.J., McMaster, M.T., De, S.K., De, M., Chang, M., Jokhai, S. and Hunt, J.S. (1988). Mouse and rat placental cell lines express abundant amounts of laminin. Placenta 9, 313-326.

40. Soares, M.J., De, M., Pinal, C.S. and Hunt, J.S. (1989). Cyclic adenosine- 3',5'-monophosphate analogues modulate rat placental cell growth and differentiation. Biology of Reproduction 40, 435-447.

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41. Hunt, J.S., Deb, S., Faria, T.N., Wheaton, D. and Soares, M.J. (1989). Isolation of phenotypically distinct trophoblast cell lines from normal rat chorioallantoic placentas. Placenta 10, 161-177.

42. Deb, S., Hashizume, K., Boone, K., Southard, J.N., Talamantes, F., Rawitch, A. and Soares, M.J. (1989). Antipeptide antibodies reveal structural and functional characteristics of rat placental lactogen-II. Molecular & Cellular Endocrinology 63, 45-56.

43. Ogle, T.F., Mills, T.M. and Soares, M.J. (1989). Changes in cytosolic and nuclear progesterone receptors during pregnancy in rat placenta. Biology of Reproduction 40, 1012-1019.

44. Campbell, W.J., Deb, S., Kwok, S.C.M., Joslin, J., and Soares, M.J. (1989). Differential expression of placental lactogen-II and prolactin-like protein-A in the rat chorioallantoic placenta. Endocrinology 125, 1565-1574.

45. Hunt, J.S., Soares, M.J., Lei, M.-G., Smith, R.N., Wheaton, D., Atherton, R. and Morrison, D.C. (1989). Products of LPS-activated macrophages (TNF-α, TGF-ß) but not LPS modify DNA synthesis by trophoblast cells exhibiting the 80 KDA LPS-binding protein. Journal of Immunology 143, 1606-1613.

46. Deb, S., Youngblood, T., Rawitch, A. and Soares, M.J. (1989). Placental prolactin-like protein-A: identification and characterization of two major glycoprotein species with antipeptide antibodies. Journal of Biological Chemistry 264, 14348-14353.

47. Meager, R., Amsden, A., Hunt, J., Soares, M.J., Sogor, L. and Smith, R.N. (1990). Placental CSF-like activity. Experimental Hematology 18, 448-451.

48. Faria, T.N., Deb, S., Kwok, S.C.M., Talamantes, F. and Soares, M.J. (1990). Ontogeny of placental lactogen-I and placental lactogen-II expression in the developing rat placenta. Developmental Biology 141, 279-291.

49. Faria, T.N., Deb, S., Kwok, S.C.M., Vandeputte, M., Talamantes, F. and Soares, M.J. (1990). Transplantable rat choriocarcinoma cells express placental lactogen: identification of placental lactogen-I immunoreactive protein and messenger ribonucleic acid. Endocrinology 127, 3131-3137.

50. Deb, S. and Soares, M.J. (1990). Characterization of placental prolactin-like protein-A in intracellular and extracellular compartments. Molecular & Cellular Endocrinology 74, 163-172.

51. Faria, T.N., Ogren, L., Talamantes, F., Linzer, D.I.H. and Soares, M.J. (1991). Localization of placental lactogen-I in trophoblast giant cells of the mouse placenta. Biology of Reproduction 44, 327-331.

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52. Deb, S., Faria, T.N., Roby, K.F., Larsen, D., Kwok, S.C.M., Talamantes, F. and Soares, M.J. (1991). Identification and characterization of a new member of the placental prolactin family: placental lactogen-I variant. Journal of Biological Chemistry 266, 1605-1610.

53. Campbell, W.J., Larsen, D., Deb., S., Kwok, S.C.M. and Soares, M.J. (1991) Expression of alkaline phosphatase in differentiated rat labyrinthine trophoblast tissue. Placenta 12, 227-237.

54. Deb, S., Roby, K.F., Faria, T.N., Larsen, D., and Soares, M.J. (1991) Identification and immunochemical characterization of a major placental secretory protein related to the prolactin-growth hormone family, prolactin-like protein-C. Endocrinology 128, 3066-3072.

55. Roby, K.F., Larsen, D., Deb, S., and Soares, M.J. (1991) Generation and characterization of antipeptide antibodies to rat cytochrome P-450 side chain cleavage enzyme. Molecular & Cellular Endocrinology 79, 13-20.

56. Soares, M.J. and Proudman, J.P. (1991) Turkey and chicken prolactins stimulate the proliferation of rat Nb2 lymphoma cells. Proceedings of the Society for Experimental Biology & Medicine 197, 384-386.

57. Deb, S., Roby, K.F., Faria, T.N., Szpirer, C., Levan, G., Kwok, S.C.M., and Soares, M.J. (1991) Molecular cloning and characterization of prolactin-like protein-C complementary deoxyribonucleic acid. Journal of Biological Chemistry 266, 23027-23032.

58. Faria, T.N. and Soares, M.J. (1991) Trophoblast cell differentiation: establishment, characterization, and modulation of a rat trophoblast cell line expressing members of the placental prolactin family. Endocrinology 129, 2895-2906.

59. Glasser, S.R., Julian, J., Mani, S.K., Mulholland, J., Munir, M.I., Lampelo, S. and Soares, M.J. (1991). Blastocyst-endometrial relationships: reciprocal interactions between uterine epithelial and stromal cells and blastocysts. Trophoblast Research 5, 229-280.

60. Soares, M.J., Faria, T.N., Roby, K.F., and Deb, S. (1991) Pregnancy and the prolactin family of hormones: coordination of anterior pituitary, uterine, and placental expression. Endocrine Reviews 12, 402-423.

61. Arbogast, L.A., Soares, M.J., Tomogane, H., and Voogt, J.L. (1992) A trophoblast specific factor(s) suppresses circulating PRL levels and increases tyrosine hydroxylase activity in tuberoinfundibular dopaminergic neurons. Endocrinology 131, 105-113.

62. Tomogane H, Arbogast L.A., Soares M.J., Robertson, M., and Voogt, J.L. (1993) A factor(s) from a rat trophoblast cell line inhibits prolactin secretion in vitro and in vivo. Biology of Reproduction 48, 325-332.

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63. Vu, A.L., Green, C.B., Roby, K.F., Soares, M.J., Fei, D.T.W., Chen, A.B., and Kwok, S.C.M. (1993) Expression of biologically active porcine prorelaxin in Chinese hamster ovary cells. Life Sciences 52, 1055-1061.

64. Roby, K.F., Deb, S., Gibori, G., Szpirer, C., Levan, G., Kwok, S.C.M., and Soares, M.J. (1993) Decidual prolactin related protein: identification, molecular cloning and characterization. Journal of Biological Chemistry 268, 3136-3142.

65. Shida, M.M., Ng, Y.-K., Soares, M.J., Linzer, D.I.H. (1993) Trophoblast-specific transcription from the mouse placental lactogen I gene promoter. Molecular Endocrinology 12, 181-188.

66. Deb, S., Hamlin, G.P., Kwok, S.C.M., and Soares, M.J. (1993) Heterologous expression and characterization of prolactin-like protein-A: identification of serum binding proteins. Journal of Biological Chemistry 268, 3298-3305.

67. Roby, K.F. and Soares, M.J. (1993) Trophoblast cell differentiation and organization: role of fetal and ovarian signals. Placenta 14, 529-545.

68. Ogle, T.F., Soares, M.J., Zhou, Y., Chorich, L., and Mahesh, V.B. (1993) Regulation of the estrogen receptor and estrogen receptor messenger ribonucleic acid in rat uteroplacental tissues during pregnancy. Life Science Advances 12, 1-12.

69. Kwok, S.C.M., Soares, M.J., McMurtry, J.P., and Yurewicz, E.C. (1993) Binding characteristics and immunolocalization of porcine seminal protein, PSP-I. Molecular Reproduction & Development 35, 244-250.

70. Arbogast, L.A., Soares, M.J., Robertson, M.C., and Voogt, J.L. (1993) A trophoblast-specific factor(s) increases tyrosine hydroxylase activity in fetal hypothalamic cell cultures. Endocrinology 133, 111-120.

71. Kwok, S.C.M., Yang, D., Dai, G., Soares, M.J., Chen, S., and McMurtry, J.P. (1993) Molecular cloning and sequence analysis of two porcine seminal proteins, PSP-I and PSP-II: new members of the sperm adhesin family. DNA & Cell Biology 12, 605-610.

72. Lu, X.-J., Deb, S., and Soares, M.J. (1994) Spontaneous differentiation of trophoblast cells along the spongiotrophoblast pathway: expression of members of the placental prolactin gene family and modulation by retinoic acid. Developmental Biology 163, 86-97.

73. Yamamoto, T., Roby, K.F., Kwok, S.C.M., and Soares, M.J. (1994) Transcriptional activation of cytochrome P450 side chain cleavage enzyme expression during trophoblast cell differentiation. Journal of Biological Chemistry 269, 6517-6523.

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74. Hamlin, G.P., Lu, X.-J., Roby, K.F., and Soares, M.J. (1994) Recapitulation of the pathway for trophoblast giant cell differentiation in vitro: stage-specific expression of members of the prolactin gene family. Endocrinology 134, 2390-2396.

75. Roby, K.F., Hamlin, G.P., Soares, M.J., and Hunt, J.S. (1994) Differential responses of phenotypically distinct rat trophoblast cell lines to MHC class I antigen-inducing cytokines. Placenta 15, 577-590.

76. Yamaguchi, M., Ogren, L., Endo, H., Soares, M.J., and Talamantes, F. (1994) Co-localization of placental lactogen-I, placental lactogen-II, and proliferin in the mouse placenta at midpregnancy. Biology of Reproduction 51, 1188-1192.

77. Gu, Y., Soares, M.J., Srivastava, R.K., and Gibori, G. (1994) Expression of decidual prolactin-related protein in the rat decidua. Endocrinology 135, 1422-1427.

78. Hamlin, G.P. and Soares, M.J. (1995) Regulation of DNA synthesis in proliferating and differentiating trophoblast cells: involvement of transferrin, transforming growth factor-β, and tyrosine kinases. Endocrinology 136, 322-331.

79. Soares, M.J., Chapman, B.M., Kamei, T., and Yamamoto, T. (1995) Trophoblast cell differentiation: lessons from the genetics of early pregnancy loss and trophoblast neoplasia. Development, Growth & Differentiation 37, 355-364

80. Yamamoto, T., Chapman, B.M., Clemens, J.W., Richards, J.S., and Soares, M.J. (1995) Analysis of cytochrome P450 side-chain cleavage gene promoter activation during trophoblast cell differentiation. Molecular & Cellular Endocrinology 113, 183-194

81. De, S.K., Larsen, D.B., and Soares, M.J. (1995) Trophoendodermal stem cell-derived extracellular matrices: absence of detectable entactin and presence of multiple laminin species. Placenta 16, 701-718

82. Cohick, C.B., Dai, G., Xu, L., Deb, S., Kamei, T., Levan, G., Szpirer, C., Kwok, S.C.M., and Soares, M.J. (1996) Placental lactogen-I variant utilizes the prolactin receptor signaling pathway. Molecular & Cellular Endocrinology 116, 49-58

83. Soares, M.J., Chapman, B.M., Rasmussen, C.A., Dai, G., Kamei, T., and Orwig, K.E. (1996) Differentiation of trophoblast endocrine cells. Placenta 17, 277-289

84. Shirai, T., Itonori, S., Soares, M.J., Shiota, K., Ogawa, T. (1996) Ganglioside composition of the rat choriocarcinoma cell line, Rcho-1. Glycoconjugate Journal 13, 415-421

85. Voogt, J.L., Soares, M.J., Robertson, M.C., and Arbogast, L.A. (1996) Rat placental lactogen-I abolishes nocturnal prolactin surges in the pregnant rat. Endocrine 4, 233-238

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86. Yamamoto, T., Chapman, B.M., Johnson, D.C., Givens, C.R., Mellon, S.H., and Soares, M.J. (1996) Cytochrome P450 17α-hydroxylase gene expression in differentiating rat trophoblast cells. Journal of Endocrinology 150, 161-168

87. Grümmer, R., Hellmann, P., Traub, O., Soares, M.J., and Winterhager, E. (1996) Regulation of connexin 31 gene expression upon retinoic acid treatment in rat choriocarcinoma cells. Experimental Cell Research 227, 23-32

88. Dai, G., Liu, B., Levan, G., Szpirer, C., Kwok, S.C.M., and Soares, M.J. (1996) Prolactin-like protein-C variant: complementary DNA, unique six exon gene structure, and trophoblast cell-specific expression. Endocrinology 137, 5009-5019

89. Dai, G., Imagawa, W., Liu, B., Levan, G., Szpirer, C., Kwok, S.C.M., and Soares, M.J. (1996) Rcho-1 trophoblast cell placental lactogens: complementary DNAs, heterologous expression, and biological activities. Endocrinology 137, 5020-5027

90. Rasmussen, C.A., Hashizume, K., Orwig, K.E., Xu, L., and Soares, M.J. (1996) Decidual prolactin-related protein: heterologous expression and characterization. Endocrinology 137, 5558-5566

91. Orwig, K.E., Rasmussen, C.A., and Soares, M.J. (1997) Decidual signals in the establishment of pregnancy: the prolactin family. Trophoblast Research 10, 329-343

92. Cohick, C.B., Xu, L., and Soares, M.J. (1997) Placental prolactin-like protein-B: heterologous expression and characterization of placental and decidual species. Journal of Endocrinology 152, 291-302

93. Manzella, S.M., Dharmesh, S.M., Cohick, C.B., Soares, M.J., Baenziger, J.U. (1997) Developmental regulation of a pregnancy-specific oligosaccharide structure, NeuAcα2,6GalNAcβ1,4GlcNAc on select members of the rat placental prolactin family. Journal of Biological Chemistry 271, 4775-4782

94. Rasmussen, C.A., Orwig, K.E., Vellucci, S., and Soares, M.J. (1997) Dual expression of prolactin-related protein in decidua and trophoblast tissues during pregnancy. Biology of Reproduction 55, 647-654

95. Orwig, K.E., Dai, G., Rasmussen, C.A., and Soares, M.J. (1997) Decidual/trophoblast prolactin related protein: characterization of gene structure and cell-specific expression. Endocrinology 138, 2491-2500

96. Shi, F., Soares, M.J., Avery, M., Liu, F., Zhang, X., and Audus, K.L. (1997) Permeability and metabolic properties of a trophoblast cell line (HRP-1) derived from normal rat placenta. Experimental Cell Research 234, 147-155

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97. Yamamoto, T., Chapman, B.M., and Soares, M.J. (1997) Protein kinase C-dependent and independent mechanisms controlling rat trophoblast cell DNA synthesis and differentiation. Journal of Reproduction & Fertility 111, 15-20

98. Kamei, T., Hamlin, G.P., Chapman, B.M., Burkhardt, A.L., Bolen, J.B., and Soares, M.J. (1997) Signaling pathways controlling trophoblast cell differentiation: Src-family protein tyrosine kinases. Biology of Reproduction 57, 1302-1311

99. Liu, F., Soares, M.J., and Audus, K.L. (1997) Permeability properties of monolayers of the human trophoblast cell line, BeWo. American Journal of Physiology 273, C1596-C1604

100.Orwig, K.E., Ishimura, R., Müller, H., Liu, B., and Soares, M.J. (1997) Identification and characterization of a mouse homolog for decidual/trophoblast prolactin-related protein. Endocrinology 139, 5511-5517

101.Müller, H., Ishimura, R., Orwig, K.E., Liu, B., and Soares, M.J. (1998) Homologues for prolactin-like protein-A and B are present in the mouse. Biology of Reproduction 58, 45-51

102.Soares, M.J., Dai, G., Orwig, K.E., Peters, T.J., and Müller, H.M. (1998) The uteroplacental prolactin family and pregnancy. Biology of Reproduction 58, 273-284

103.Das, U.G., Sadiq, F., Soares, M.J., Hay, W.W., and Devaskar, S.U. (1998) Time dependent physiological regulation of rodent and ovine placental glucose transporter (Glut 1) protein. American Journal of Physiology 274, R339-R348

104.Müller, H., Orwig, K.E., and Soares, M.J. (1998) Identification of two new members of the mouse prolactin family. Biochimica Biophysica Acta 1396, 251-258

105.Müller, H., Dai, G., and Soares, M.J. (1998) Placental lactogen-I (PL-I) target tissues identified with an alkaline phosphatase-PL-I fusion protein. Journal of Histochemistry & Cytochemistry 46, 737-744

106.Orwig, K.E., Wolfe, M.W., Cohick, C.B., Dai, G., Peters, T.J., and Soares, M.J. (1998) Trophoblast-specific regulation of endocrine-related genes. Trophoblast Research 11, 65-85

107.Amura, C.R., Kamei, T., Ito, N., Soares, M.J., and Morrison, D.C. (1998) Differential regulation of lipopolysaccharide (LPS) activation pathways in mouse macrophages by LPS binding proteins. Journal of Immunology 161, 2552-2560

108.Dai, G., Chapman, B.M., Liu, B., Wang, D., Orwig, K.E., White, R.A., Preuett, B., and Soares, M.J. (1998) A new mouse member of the prolactin-like protein-C subfamily: structure and expression. Endocrinology 139, 5157-5163

109.Kenagy, J., Liu, F., Soares, M.J., and Audus, K.L. (1998) Gestational and smoking effects on peptidase activity in the placenta. Peptides 19, 1659-1666

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110.Peters, T.J., Albieri, A., Bevilaqua, E., Chapman, B.M., Crane, L., Hamlin, G.P., Seiki, M., and Soares, M.J. (1999) Differentiation-dependent expression of gelatinase B/MMP-9 in rat trophoblast cells. Cell & Tissue Research 295, 287-296

111.Dai, G., Chapman, B.M., Wang, D., White, R.A., Preuett, B., and Soares, M.J. (1999) Prolactin-like protein-A gene structure and chromosomal mapping. Mammalian Genome 10, 78-80.

112.Knipp, G.T., Audus, K.L., and Soares, M.J. (1999) Nutrient transport across the placenta. Advanced Drug Delivery Reviews 38, 41-58

113.Müller, H., Liu, B., Croy, B.A., Head, J.R., Hunt, J.S., Dai, G., and Soares, M.J. (1999) Uterine natural killer cells are targets for a trophoblast cell-specific cytokine, prolactin-like protein-A. Endocrinology 140, 2711-2720

114.Orwig, K.E. and Soares, M.J. (1999) Transcriptional activation of the decidual/trophoblast prolactin-related protein gene. Endocrinology 140, 4032-4039

115.Dai, G., Wolfe, M.W., and Soares, M.J. (1999) Distinct regulatory regions from the prolactin-like protein-C variant promoter direct trophoblast giant cell versus spongiotrophoblast cell-specific expression. Endocrinology 140, 4691-4698

116.Sahgal, N., Knipp, G.T., Liu, B., Chapman, B.M., Dai, G., and Soares, M.J. (2000) Identification of two new nonclassical members of the rat prolactin family. Journal of Molecular Endocrinology 24, 95-108

117.Lee, Y., Yang, S.-P., Soares, M.J., and Voogt, J.L. (2000) Distribution of prolactin releasing peptide (PrRP) mRNA in the rat brain. Brain Research Bulletin 51, 171-176

118.Peters, T.J. Chapman, B.M., Wolfe, M.W. and Soares, M.J. (2000) Placental lactogen-I gene activation in differentiating trophoblast cells: extrinsic and intrinsic regulation involving mitogen-activated protein kinase signaling pathways. Journal of Endocrinology 165, 443-456

119.Knipp, G.T., Liu, B., Audus, K.L., Fujii, H., Ono, T., and Soares, M.J. (2000) Fatty acid transport regulatory proteins in the developing rat placenta and in trophoblast cell culture models. Placenta 21, 367-375

120.Dai, G., Wang, D., Liu, B., Kasik, J.W., Müller, H., White, R.A., Hummel, G.S., and Soares, M.J. (2000) Three novel paralogs of the rodent prolactin gene family. Journal of Endocrinology 166, 63-75

121.Bittorf, T., Jaster, R., Soares, M.J., Seiler, J., Brock, J., Friese, K., and Müller, H. (2000) Induction of erythroid proliferation and differentiation by a trophoblast-specific cytokine

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involves activation of the Jak/STAT pathway. Journal of Molecular Endocrinology 25, 253-262

122.Wang, D., Ishimura, R., Walia, D.S., Müller, H., Dai, G., Hunt, J.S., Lee, N.A., Lee, J.J., and Soares, M.J. (2000) Eosinophils are cellular targets of the novel uteroplacental heparin-binding cytokine, decidual/trophoblast prolactin-related protein. Journal of Endocrinology 167, 15-29

123.Peters, T.J., Chapman, B.M., and Soares, M.J. (2000) Trophoblast differentiation: an in vitro model for trophoblast giant cell development. Methods in Molecular Biology 137, 301-311

124.Ain, R., Müller, H., Sahgal, N., Dai, G., and Soares, M.J. (2002) Uteroplacental prolactin family: immunological regulators of viviparity. Neuroimmune Biology 2, 187-202

125.Audus, K.L., Soares, M.J., and Hunt, J.S. (2002) Characteristics of the fetal/maternal interface with potential usefulness in the development of future immunological and pharmacological strategies. Journal of Pharmacology and Experimental Therapeutics 301, 402-409

126.Ain, R., Tash, J.S., and Soares, M.J. (2002) A simple method for the in situ detection of eosinophils. Journal of Immunological Methods 260, 273-278

127.Kamei, T., Jones, S.R., Chapman, B.M., McGonigle, K., Dai, G., and Soares, M.J. (2002) Activation and involvement of the phosphatidylinositol 3-kinase/akt-signaling pathway in the endocrine differentiation of trophoblast cells. Molecular Endocrinology 16, 1469-1481

128.Dai, G., Lu, L., Tang, S., Peal, M.J., and Soares, M.J. (2002) The prolactin family miniarray: a tool for evaluating uteroplacental/trophoblast endocrine cell phenotypes. Reproduction 124, 755-765

129.Wiemers, D.O., Shao, L.-J., Ain, R., Dai, G., and Soares, M.J. (2003) The mouse prolactin gene family locus. Endocrinology 144, 313-325

130.Ain, R., Tash, J.S., and Soares, M.J. (2003) Prolactin-like protein-A is a functional modulator of natural killer cells at the maternal-fetal interface. Molecular and Cellular Endocrinology 204, 65-74

131.Ain, R., Canham, L.N., and Soares, M.J. (2003) Gestational stage-dependent intrauterine trophoblast cell invasion in the rat and mouse: novel endocrine phenotype and regulation. Developmental Biology 260, 176-190

132.Zhou, F.-F., Tanaka, K., Soares, M.J., and You, G. (2003) Characterization of an organic anion transport system in a placental cell line. American Journal of Physiology 285, E1103-E1109

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133.Wiemers, D.O., Ain R, Ohboshi, S., and Soares, M.J. (2003) Migratory trophoblast cells express a newly identified member of the prolactin gene family. Journal of Endocrinology 179, 335-346

134.Soares, M.J. and Wolfe, M.W. (2004) Human embryonic stem cells ‘assemble’ and fulfill their developmental ‘destiny’. Endocrinology 145, 1514-1516

135.Ain, R. and Soares, M.J. (2004) Is the metrial gland really a gland? Journal of Reproductive Immunology 61, 129-131

136.Soares, M.J. (2004) The prolactin and growth hormone families: pregnancy-specific hormones/cytokines at the maternal-fetal interface. Reproductive Biology & Endocrinology 2, 51 (http://www.rbej.com/content/2/1/51)

137.Asano, N., Kondoh, M., Ebiara, C., Fujii, M., Soares, M.J., Nakashima, E., Sato, M., and Watanabe, Y. (2004) Expression profiles of zinc transporters in rodent placental models. Toxicology Letters 154, 45-53

138.Ain, R., Trinh, M.-L., and Soares, M.J. (2004) Interleukin-11 signaling is required for the differentiation of natural killer cells at the maternal-fetal interface. Developmental Dynamics 231, 700-708

139.Ain, R., Dai, G., Dunmore, J.H., Godwin, A.R., and Soares, M.J. (2004) A prolactin family paralog regulates reproductive adaptations to a physiological stressor. Proceedings of the National Academy of Sciences U.S.A. 101, 16543-16548

140.Thadani, P.V., Strauss, J.F., Dey, S.K., Anderson, V.M., Audus, K.L., Coats, K.S., Cross, J.C., Erlebacher, A., Ganapathy, V., Linzer, D.I., Miller, R.K., Novak, D.A., Rapaka, R.S., Sadovsky, Y., Salafia, C.M., Soares, M.J., and Unadkat, J. (2004) NIDA conference report on placental proteins, drug transport, and fetal development. American Journal of Obstetrics and Gynecology 191, 1858-1862

141.Rider, V., Potapova, T, Dai, G., and Soares, M.J. (2005) Stimulation of a rat uterine stromal cell line in culture reveals a molecular switch for endocrine-dependent differentiation. Journal of Endocrinology 184, 119-127

142.Ain, R., Canham, L.N., and Soares, M.J. (2005) Dexamethasone-induced intrauterine growth restriction impacts the placental prolactin family and the insulin-like growth factor-II/Akt signaling pathway. Journal of Endocrinology 185, 253-263

143.Arroyo, J.A., Konno, T., Khalili, D., and Soares, M.J. (2005) A simple in vivo approach to investigate invasive trophoblast cells. International Journal of Developmental Biology 49, 977-980.

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http://www.rbej.com/content/2/1/51


144.Berghorn, K.A., Clark, P.A., Encarnacion, B., DeRegis, C.J., Folger, J., Morasso, M.I., Soares, M.J., Wolfe, M.W., and Roberson, M.S. (2005) Developmental expression of the homeobox protein Distal-less 3 and its relationship to progesterone production in mouse placenta. Journal of Endocrinology 186, 315-323

145.Sahgal, N., Canham, L.N., Konno, T., Wolfe, M.W., and Soares, M.J. (2005) Modulation of trophoblast stem cell and giant cell phenotypes: analyses using the Rcho-1 cell model. Differentiation 73, 452-462.

146.Soares, M.J., Alam, S.M.K., Konno, T., Ho-Chen, J.K., and Ain, R. (2006) The prolactin gene family and pregnancy-dependent adaptations. Animal Science Journal 77, 1-9.

147.Alam, S.M.K., Ain, R., Konno, T., Ho-Chen, J.K., and Soares, M.J. (2006) The rat prolactin gene family locus: species-specific gene family expansion. Mammalian Genome 17, 858-877.

148.Singh, U., Yu, Y., Kalinina, E., Konno, T., Sun, T., Wakayama, T., Soares, M.J., Hemberger, M., and Fundele, R.H. (2006) Carboxypeptidase E in the mouse placenta. Differentiation 74, 648-660.

149.Alam, S.M.K., Konno, T., Dai, G., Lu, L., Wang, D., Dunmore, J.H., Godwin, A.R., and Soares, M.J. (2007) A uterine decidual cell cytokine ensures pregnancy-dependent adaptations to a physiological stressor. Development 134, 407-415.

150.Ho-Chen, J.K., Bustamante, J.J., and Soares, M.J. (2007) Prolactin-like protein-F subfamily of placental hormones/cytokines: responsiveness to maternal hypoxia. Endocrinology 148, 559-565.

151.Konno, T., Rempel, L.A., Arroyo, J.A., and Soares, M.J. (2007) Pregnancy in the Brown Norway rat: a model for investigating the genetics of placentation. Biology of Reproduction 76, 709-718.

152.Soares, M.J., Konno, T., and Alam, S.M.K. (2007) The prolactin family: effectors of pregnancy-specific adaptations. Trends in Endocrinology and Metabolism 18, 114-121.

153.Soares, M.J., Alam, S.M.K., Duckworth, M.L., Horseman, N.D., Konno, T., Linzer, D.I.H., Maltais, L.J., Nilsen-Hamilton, M., Shiota, K., Smith, J.R., and Wallis, M. (2007) A standardized nomenclature for the mouse and rat prolactin superfamilies. Mammalian Genome 18, 154-156.

154.Bustamante, J.J., Dai, G., and Soares, M.J. (2008) Pregnancy and lactation modulate maternal splenic growth and development of the erythroid lineage in the rat and mouse. Reproduction, Fertility, and Development 20, 303-310.

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155.Takahashi, T., Yamada, O., Soares, M.J., and Hashizume, K. (2008) Bovine prolactin-related protein-I is anchored to the extracellular matrix through interactions with type IV collagen. Journal of Endocrinology 196, 225-234.

156.Rosario, G.X., Konno, T., and Soares, M.J. (2008) Maternal hypoxia-activated endovascular trophoblast cell invasion. Developmental Biology 314, 362- 375.

157.Yu, Y., Singh, U., Shi, W., Konno, T., Soares, M.J., Geyer R., and Fundele, R. (2008) Influence of murine maternal hyperglycemia on placental morphology, gene expression, and function. Archives of Physiology and Biochemistry 110, 99-110.

158.Truog, W.E., Xu, D., Ekekezie, I.I., Mabry, S., Rezaiekhaligh, M., Svojanovsky, S., and Soares, M.J. (2008) Chronic hypoxia and rat lung development: analysis by morphometry and directed microarray. Pediatric Research 64, 56-62.

159.Chaturvedi, G., Simone, P.D., Ain, R., Soares, M.J., and Wolfe, M.W. (2008) Noggin maintains pluripotency of human embryonic stem cells grown on Matrigel. Cell Proliferation, in press.

160.Alam, S.M.K., Konno, T., Sahgal, N., Lu, L., and Soares, M.J. (2008) Decidual cells produce a heparin-binding prolactin family cytokine with putative intrauterine regulatory actions. Journal of Biological Chemistry 283, 18957-18968.

161.Dai, G., Bustamante, J.J., and Soares, M.J. (2008) Maternal hepatic growth response to pregnancy in the mouse. American Journal of Physiology, submitted.

Chapters in Books

1. Hoffmann, J.C. and Soares, M.J. (1983). Anterior pituitary function in seasonal breeders. In A.J. Bhnatagar (ed.), The Anterior Pituitary, Raven Press: New York, pp. 295-312

2. Talamantes, F., Soares, M.J., Colosi, P., Haro, L. and Ogren, L. (1984). The biochemistry and physiology of mouse placental lactogen. In F. Mena and C. Valverde (eds.), Frontiers and Perspectives of Prolactin Secretion: A multidisciplinary approach. Academic Press: New York, pp. 31-39

3. Talamantes, F., Colosi, P., Soares, M.J., Markoff, E., Haro, L., Lopez, J., Marr, G., and Ogren, L. (1985). Studies on the biochemistry and physiology of mouse prolactin, growth hormone and placental lactogen. In B. Lofts and W.N. Holmes (eds.), Proceedings of the Ninth International Symposium on Comparative Endocrinology. Hong Kong University Press: Hong Kong, pp. 569-571

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4. Soares, M.J., Talamantes, F., Handwerger, S. (1993) A tribute to Henry G. Friesen, M.D. In M.J. Soares, S. Handwerger, and F. Talamantes (eds), Trophoblast Cells: Pathways for Maternal-Embryonic Communication, Springer-Verlag, New York, pp. xix-xxi

5. Soares, M.J., Faria, T.N., Hamlin, G.P., Lu, X.-J., and Deb, S. (1993) Trophoblast cell differentiation: expression of the placental prolactin family. In M.J. Soares, S. Handwerger, and F. Talamantes (eds), Trophoblast Cells: Pathways for Maternal-Embryonic Communication, Springer-Verlag, New York, pp. 43-65

6. Soares, M.J., Chapman, B.M., Hamlin, G.P., Kamei, T., and Yamamoto, T. (1995) Control of trophoblast cell differentiation: the Rcho-1 trophoblast cell model. Biology of Pregnancy, T. Nakayama & T. Makino (eds), Keiseisha Publishers, Tokyo, Japan, pp. 50-60

7. Hunt, J.S. and Soares, M.J. (1996) Features of the maternal-fetal interface. In: HLA and the Maternal-Fetal Relationship. J.S. Hunt (ed), Landes Publishing Co., Austin, TX, pp. 1-26

8. Hunt, J.S. and Soares, M.J. (1996) The placenta. In The Physiology of Immunity, J.A. Marsh and M.D. Kendall (eds), CRC Press, Boca Raton, pp. 277-295

9. Soares, M.J. (1997) Molecular mechanisms of placental development. In: Placental Function and Fetal Nutrition. F.C. Battaglia (ed), Lippincott-Aven Publishers, Philadelphia, pp. 41-53

10. Soares, M.J., Dai, G., Cohick, C.B., Müller, H., and Orwig, K.E. (1998) The rodent placental prolactin family and pregnancy. In: Endocrinology of Pregnancy, F.W. Bazer (ed), Humana Press Inc., New Jersey, pp. 145-176

11. Audus, K.L., Liu, F., Ampasavate, C., Soares, M.J., and Stobaugh, J.F. (1998) Factors regulating peptide passage across the placental barrier. In: Alfred Benzon Symposium 43, Peptide and Protein Delivery, Munksgaard International Publishers Ltd., Copenhagen, pp. 67-74

12. Soares, M.J., Wang, D., Sahgal, N., Müller, H., and Dai, G. (2000) Uteroplacental signals in the establishment of pregnancy: The prolactin family. In: Clone Animals and Placentation, K. Hashizume (ed), Yokendo Publishers, Tokyo, Japan, pp. 123-130

13. Soares, M.J. and Linzer, D.I.H. (2001) Rodent prolactin family and pregnancy. In: Prolactin, N.D. Horseman (ed), Kluwer Academic Publishers, Norwell, MA , pp. 139-167

14. Sahgal, N., Canham, L.N., Canham, B., and Soares, M.J. (2006) Rcho-1 trophoblast cells: a model for studying trophoblast differentiation. In: Placenta and Trophoblast: Methods and Protocols, Vol. 1. M.J. Soares and J.S. Hunt (eds), Humana Press, Totowa, New Jersey, pp. 159-178

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15. Ain, R., Konno, T., Canham, L.N., and Soares, M.J. (2006) Phenotypic analysis of the placenta in the rat. In: Placenta and Trophoblast: Methods and Protocols, Vol. 1. M.J. Soares and J.S. Hunt (eds), Humana Press, Totowa, New Jersey, pp. 295-313

16. Müller, H. and Soares, M.J. (2006) Alkaline phosphatase fusion proteins as tags for identifying targets for placental ligands. In: Placenta and Trophoblast: Methods and Protocols, Vol 2. M.J. Soares and J.S. Hunt (eds), Humana Press, Totowa, New Jersey, pp. 331-340

17. Ho-Chen, J.K., Ain, R., Alt, A., Wood, J.G., Gonzalez, N.C., and Soares, M.J. (2006) Hypobaric-hypoxia as a tool to study pregnancy-dependent responses at the maternal-fetal interface. In: Placenta and Trophoblast: Methods and Protocols, Vol. 2. M.J. Soares and J.S. Hunt (eds), Humana Press, Totowa, New Jersey, pp. 427-434

18. Soares, M.J., Alam, S.M.K., Konno, T., and Ain, R. (2007) The prolactin family: regulators of uterine biology. In: The Endometrium-Molecular, Cellular and Clinical Perspectives, 2nd

Edition, J. Aplin, A. Fazleabas, S.R. Glasser, L. Giudice (eds), Taylor and Francis Publishers, London, pp. 342-353

Books (Edited)

Soares, M.J., Handwerger, S., and Talamantes, F. (1993) Trophoblast Cells: Pathways for Maternal-Embryonic Communication. Springer-Verlag, New York

Soares, M.J. and Hunt, J.S. (2006) Placenta and Trophoblast: Methods and Protocols, Vol. 1. Humana Press, New Jersey.

Soares, M.J. and Hunt, J.S. (2006) Placenta and Trophoblast: Methods and Protocols, Vol. 2. Humana Press, New Jersey.

Book Reviews

Soares, M.J. (1994) review of: "Molecular and Cellular Biology of Reproduction", G. Spera, A. Fabbrini, L. Gnessi, Bardin C.W. (eds), Raven Press, New York, 296 pp, 1992. In: Modern Pathology 7, 627

Papers presented

1. Soares, M.J. and Hoffmann, J.C. (1980). Seasonal variations in serum androgen and luteinizing hormone levels in the male mongoose, Herpestes auropunctatus. 13th Annual meeting of the Society for the Study of Reproduction, Abstract No. 130.

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2. Soares, M.J., Colosi, P. and Talamantes, F. (1982). Identification and preliminary characterization of a midpregnancy prolactin-like hormone secreted by mouse decidua-giant cell organ cultures. 64th Annual meeting of the Endocrine Society, Abstract No. 878.

3. Soares, M.J. and Talamantes, F. (1982). Midpregnancy elevation of serum androstenedione levels in the C3H/HeN mouse: placental origin. 33rd Annual Fall meeting of the American Physiological Society, Abstract No. 29.18.

4. Soares, M.J. and Talamantes, F. (1983). Fetal and ovarian influences on placental lactogen secretion in the mouse. Western Regional Conference on Comparative Endocrinology, Berkeley, California, Abstract No. 11.

5. Klemcke, H., Bartke, A., Soares, M.J., Talamantes, F. and Borer, K. (1983). Autoregulation of testicular prolactin receptors in golden hamsters. 65th Annual meeting of the Endocrine Society, Abstract no. 804.

6. Soares, M.J., Julian, J.A. and Glasser, S.R. (1983). Trophoblast giant cell transformation from ectoplacental cone cells. 23rd Annual meeting of the American Society for Cell Biology, Abstract no. 205.

7. Glasser, S.R., Soares, M.J. and Julian, J. (1984). Morphological and functional differentiation of rat trophectoderm in vitro: organization of microtubules, expression of cytokeratins and rat placental lactogen in midgestation trophoblast giant cells. International Symposium on Mammalian Reproduction and Early Development. Tokyo, Japan.

8. Soares, M.J. and Glasser, S.R. (1984). Multiple low molecular weight placental lactogen variants secreted by trophoblast giant cells in vitro. 24th Annual meeting of the American Society for Cell Biology, Abstract no. 990.

9. Soares, M.J. and Glasser, S.R. (1985). Progesterone modulates the differentiation of trophoblast giant cells in vitro. Tenth International Congress of the International Society of Developmental Biologists, Los Angeles, California.

10. Glasser, S.R., Julian, J., Munir, M.I and Soares, M.J. (1987). Biomarkers during early pregnancy: endometrial and trophoblastic signals. National Research Council/National Academy of Sciences, Environmental Protection Agency and National Institute of Environmental Health Sciences: Role of Biological markers in Reproductive and Developmental Toxicology, Washington, D.C.

11. Soares, M.J., De, S.K. and Andrews, G.K. (1987). Establishment of a rat placental cell line expressing characteristics of extraembryonic membranes. Fifth International Meeting of International Society of Differentiation, Boulder, Colorado.

12. De, S.K. and Soares, M.J. (1987). Purification and partial characterization of two biochemically different laminins from tissue transplants derived from a rat placental cell line.

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Fifth International Meeting of the International Society of Differentiation, Boulder, Colorado.

13. vom Saal, F.S., Even, M.D., Soares, M.J. and Johnson, D.C. (1987). Maternal stress reduces placental 17α-hydroxylase and C17,20 lyase activity in mice (Mus musculus). 20th Annual Meeting of the Society for the Study of Reproduction, Champaign-Urbana, Illinois.

14. Soares, M.J., Hashizume, K., Deb, S. and Hunt, J.S. (1988). Placental lactogen-II and related peptides identified in the chorioallantoic placenta and trophoblast cell lines with antipeptide antisera. Reproductive Tract Biology Gordon Conference, Brewster Academy, Wolfeboro, New Hampshire, July, 1988.

15. Deb, S., Boone, K., Rawitch, A. and Soares, M.J. (1988). Generation of antipeptide antibodies to rat placental lactogen-II. 21st Annual Meeting of the Society for the Study of Reproduction, Seattle, Washington.

16. Hashizume, K., Hasegawa, Y., Miyamoto, K., Igarashi, M. and Soares, M.J. (1988). Developmental changes in the expression of proteins antigenically related to inhibin and gonadotropin releasing hormone (GnRH) in the rat chorioallantoic placenta and in a rat placental cell line. 21st Annual Meeting of the Society for the Study of Reproduction, Seattle, Washington.

17. Deb, S., Campbell, W.J., Youngblood, T., Rawitch, A. and Soares, M.J. (1989). Placental prolactin-like protein-A: identification and characterization of two major glycoprotein species with antipeptide antibodies. 71st Annual Meeting of the Endocrine Society, Seattle, Washington.

18. Campbell, W.J., Deb, S., Kwok, S.C.M. and Soares, M.J. (1989). Differential expression of placental prolactins in junctional and labyrinth zones of the rat placenta. 71st Annual Meeting of the Endocrine Society, Seattle, Washington.

19. Campbell, W.J. and Soares, M.J. (1989). Establishment of a porcine embryonically-derived cell line. 22nd Annual Meeting of the Society for the Study of Reproduction, Columbia, Missouri.

20. Hunt, J.S., Soares, M.J. and Morrison, D.C. (1989). Products of LPS-activated macrophages (TNF-α, TGF-ß) but not LPS modify DNA synthesis by LPS receptor- bearing rat trophoblast cells. 4th International Congress of Reproductive Immunology, Kiel, Federal Republic of Germany.

21. Faria, T.N., Deb., S., Kwok, S.C.M., Talamantes, F. and Soares, M.J. (1990). Ontogeny of placental lactogen-I and placental lactogen-II expression in the developing rat placenta. 72nd

Annual Meeting of the Endocrine Society, Atlanta, Georgia.

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22. Deb, S. and Soares, M.J. (1990). Prolactin-like protein-A circulates as biologically latent disulfide-linked high molecular weight complexes. 72nd Annual Meeting of the Endocrine Society, Atlanta, Georgia.

23. Hunt, J.S. and Soares, M.J. (1990). Cytokine influences on rat trophoblast cells. International Conference on Placenta, Tokyo, Japan.

24. Roby, K.F. and Soares, M.J. (1991). Endocrine differentiation of rat trophoblast cells: roles of the fetus, ovary, and ovarian steroid hormones. 73rd Annual Meeting of the Endocrine Society, Washington, DC.

25. Faria, T.N. and Soares, M.J. (1991). Establishment and characterization of a placental lactogen-secreting rat trophoblast cell line. 73rd Annual Meeting of the Endocrine Society, Washingtion, DC.

26. Roby, K.F. and Soares, M.J. (1991). Biochemical characterization of rat decidual and placental prolactin-like protein-B immunoreactive proteins. 24th Annual Meeting of the Society for the Study of Reproduction, Vancouver, BC.

27. Arbogast, L.A., Soares, M.J., and Voogt, J.L. (1991) A placental factor increases tyrosine hydroxylase (TH) activity in tuberoinfundibular dopaminergic (TIDA) neurons. 1991 Annual Meeting of the Society for Neuroscience, New Orleans, LA.

28. Shida, M., Ng, Y.K., Soares, M.J., and Linzer, D.I.H. (1991) Tissue specific expression of the mouse placental lactogen I gene. Annual Meeting of the American Society of Cell Biology, Boston, MA.

29. Deb, S., Hamlin, G., Roby, K.F., Kwok, S.C.M., and Soares, M.J. (1992) Generation and characterization of recombinant prolactin-like protein-A. GORDON CONFERENCE ON PROLACTIN, Oxnard, California, February, 1992.

30. Shida, M., Ng, Y.K., Soares, M.J., and Linzer, D.I.H. (1992) Transcriptional regulation of mouse placental lactogen I gene expression: role of AP-1. 74th Annual Meeting of the Endocrine Society, San Antonio, Texas.

31. Arbogast, L.A., Soares, M.J., Robertson, M.C., and Voogt, J.L. (1992) A trophoblast-specific factor(s) increases tyrosine hydroxylase (TH) activity in fetal hypothalamic cell cultures. Annual Meeting of the Society for Neuroscience, Anaheim, California.

32. Yamamoto, T., Roby, K.F., and Soares, M.J. (1993) Transcriptional activation of cytochrome P450 side chain cleavage enzyme expression during trophoblast cell differentiation. 75th Annual Meeting of the Endocrine Society, Las Vegas, Nevada.

33. Yamaguchi, M., Ogren, L., Endo, H., Soares, M.J., Sullivan, W., and Talamantes, F. (1993) Production of mouse placental lactogen-I, placental lactogen-II, proliferin, and proliferin

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related protein by the same giant cell and differential regulation by epidermal growth factor. 75th Annual Meeting of the Endocrine Society, Las Vegas, Nevada.

34. Shiota, K., Itonori, S., Soares, M.J., Ohashi, Y, and Ogawa, T. (1993) Expression of glycolipids and placental lactogen mRNA in rat choriocarcinoma cell line (Rcho-1). International Symposium on Glycoconjugates, Krakow, Poland.

35. Gu, Y., Soares, M.J., and Gibori, G. (1993) Rat decidual PRL-related protein gene: cell specific expression and regulation. 26th Annual Meeting of the Society for the Study of Reproduction, Fort Collins, Colorado.

36. Kwok, S.C.M., Yang, D., Dai, G., Soares, M.J., Chen, S., and McMurtry, J.P. (1993) Molecular cloning and sequence analysis of two porcine seminal proteins, PSP-I and PSP-II. 26th Annual Meeting of the Society for the Study of Reproduction, Fort Collins, Colorado.

37. Sadiq, H.F., Morgenthaler, T.A., Schroeder, R.E., Soares, M.J., and Devaskar, S.U. (1994) Effects of hypoxia and glucose on placental glucose transporters. Annual Meeting of the American Pediatric Society.

38. Yamamoto, T., Chapman, B.M., Clemens, J.W., Richards, J.S., and Soares, M.J. (1994) Analysis of cytochrome P450 side-chain cleavage gene promoter activation during trophoblast cell differentiation. 76th Annual Meeting of the Endocrine Society, Anaheim, California.

39. Rasmussen, C.A., Hashizume, K., Vellucci, S., and Soares, M.J. (1994) Decidual prolactin- related protein: heterologous expression and characterization. 76th Annual Meeting of the Endocrine Society, Anaheim, California.

40. Hellmann, P., Gruemmer, R., Traub, O., Soares, M., Winterhager, E., and Spray, D.C. (1994) Human and rat choriocarcinoma cell lines express connexins 40 and 31, endowing these cells with unusual physiological properties. Annual Meeting of the American Society for Cell Biology, San Francisco, California.

41. Cohick, C.B., Dai, G., Xu, L., Deb, S., Kamei, T., Kwok, S.C.M., and Soares, M.J. (1995) Heterologous expression and characterization of placental lactogen-I variant. 77th Annual Meeting of the Endocrine Society, Washington D.C.

42. Hattori, N., Imai, A., Hirosawa, M., Soares, M.J., Shiota, K., and Ogawa, T. (1995) Molecular diversity of immunoreactive rat placental lactogens at mid-pregnancy. 28th Annual Meeting of the Society for the Study of Reproduction, Davis, CA

43. Hirsosawa, M., Hattori, N., Soares, M.J., Shiota, K., and Ogawa, T. (1995) Production of recombinant placental lactogen-I mosaic (rPL-Im) by a baculovirus system. 28th Annual Meeting of the Society for the Study of Reproduction, Davis, CA

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44. Kamei, T. and Soares, M.J. (1995) Identification of a novel serine-threonine kinase activated during trophoblast giant cell differentiation. 28th Annual Meeting of the Society for the Study of Reproduction, Davis, CA

45. Orwig, K.E. and Soares, M.J. (1995) Establishment and characterization of a rat primary decidual cell culture system that expresses and secretes the decidual prolactin related protein. 28th Annual Meeting of the Society for the Study of Reproduction, Davis, CA

46. Rasmussen, C.A., Orwig, K.E., and Soares, M.J. (1995) Ontogeny of decidual prolactin-related protein expression in the rat during pregnancy. 28th Annual Meeting of the Society for the Study of Reproduction, Davis, CA

47. Grummer, R., Reub, B., Hellmann, P., Soares, M.J., and Winterhager, E. (1995) Regulation of connexin gene expression during trophoblast differentiation. Annual Meeting of the American Society for Cell Biology, Washington, D.C.

48. Rasmussen, C.A., Orwig, K.E., and Soares, M.J. (1996) Characterization and possible functions of decidual prolactin-related protein. "The Maternal-Placental-Fetal Dialogue" an International Workshop sponsored by the Science and Technology Agency of Japan. Maui, Hawaii

49. Kamei, T., Hamlin, G.P., and Soares, M.J. (1996) Lyn tyrosine protein kinase activation and intracellular interactions during trophoblast giant cell differentiation. "The Maternal-Placental-Fetal Dialogue" an International Workshop sponsored by the Science and Technology Agency of Japan. Maui, Hawaii

50. Orwig, K.E., Dai, G., and Soares, M.J. (1996) Decidual prolactin related protein gene structure is unique among prolactin family members. 78th Annual Meeting of the Endocrine Society, San Francisco, CA

51. Dai, G. and Soares, M.J. (1996) Prolactin-like protein-C variant: unique six exon gene structure, and expression. 78th Annual Meeting of the Endocrine Society, San Francisco, CA

52. Dai, G. and Soares, M.J. (1996) Rcho-1 trophoblast cell placental lactogens: complementary DNAs, heterologous expression and biological activities. 29th Annual Meeting of the Society for the Study of Reproduction, London, Ontario.

53. Liu, F., Soares, M.J., Audus, K.L. (1996) Permeability properties of human trophoblast cell (BeWo) monolayers. Annual Meeting of the American Association of Pharmaceutical Sciences, Seattle, WA

54. Liu, F., Soares, M.J., Kenagy, J., and Audus, K.L. (1996) Metabolic properties of the human placenta: tissue, primary trophoblast cultures, and a trophoblast cell line (BeWo). Annual Meeting of the American Association of Pharmaceutical Sciences, Seattle, WA

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55. Liu, F., Soares, M.J., Audus, K.L. (1996) Permeability and biochemical properties of BeWo trophoblast cell monolayers. 13th Annual Rochester Trophoblast Conference, Banff, Canada

56. Peters, T.J. and Soares, M.J. (1996) Regulation of placental lactogen-I in differentiating trophoblast cells. 13th Annual Rochester Trophoblast Conference, Banff, Canada

57. Müller, H., Dai, G., and Soares, M.J. (1997) Generation and characterization of a placental lactogen-I (PL-I)-alkaline phosphatase fusion protein for the identification of PL-I target tissues. 79th Annual Meeting of the Endocrine Society, Minneapolis, MN

58. Peters, T.J., Das, S.K., Dey, S.K., and Soares, M.J. (1997) Trophoblast giant cell endocrine differentiation via autocrine/paracrine mechanisms involving the epidermal growth factor receptor signaling pathway. 79th Annual Meeting of the Endocrine Society, Minneapolis, MN

59. Chapman, B.M. and Soares, M.J. (1997) Receptor and nonreceptor tyrosine kinases in proliferating and differentiating trophoblast cells. 79th Annual Meeting of the Endocrine Society, Minneapolis, MN

60. Dai, G., Wolfe, M.W., and Soares, M.J. (1997) Distinct regulatory regions from the prolactin-like protein-C variant promoter direct trophoblast giant cell versus spongiotrophoblast cell-specific expression. 79th Annual Meeting of the Endocrine Society, Minneapolis, MN

61. Orwig, K.E. and Soares, M.J. (1997) Promoter analysis of the gene encoding the decidual/trophoblast prolactin-related protein. 30th Annual Meeting of the Society for the Study of Reproduction, Portland, OR

62. Peters, T.J., Albieri, A., Bevilaqua, E., and Soares, M.J. (1997) Differentiation-dependent expression of gelatinase B/MMP-9 in rat trophoblast cells. 30th Annual Meeting of the Society for the Study of Reproduction, Portland, OR

63. Cohick, C.B. and Soares, M.J. (1998) Transcriptional regulation of P450 side-chain cleavage gene in differentiating trophoblast cells. 80th Annual Meeting of the Endocrine Society, New Orleans, LA

64. Müller, H., Dai, G., Croy, B.A., Head, J.R., Liu, B., and Soares, M.J. (1998) Pregnancy-associated natural killer cells are regulated by a trophoblast-specific cytokine. 80th Annual Meeting of the Endocrine Society, New Orleans, LA

65. Wang, D., Ishimura, R., Müller, H., Dai, G., and Soares, M.J. (1998) Target cells for decidual/trophoblast prolactin-related protein within the uteroplacental compartment. 80th Annual Meeting of the Endocrine Society, New Orleans, LA

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66. Dai, G., Takahashi, T., Liu, B., Chapman, B.M., Müller, H., and Soares, M.J. (1998) Heterologous expression and identification of target tissues for prolactin-like protein-C (PLP-C) and PLP-C variant (PLP-Cv). 80th Annual Meeting of the Endocrine Society, New Orleans, LA

67. Dai, G., Liu, B., Chapman, B.M., Orwig, K.E., Wang, D., and Soares, M.J. (1998) A new mouse member of the prolactin-like protein-C subfamily: structure and expression. 80th Annual Meeting of the Endocrine Society, New Orleans, LA

68. Sahgal, N., Knipp, G.T., Liu, B., Chapman, B.M., Dai, G., and Soares M.J. (1999) Characterization of two nonclassical members of the placental prolactin family from the rat. Annual Meeting for the Society for Pediatric Research, San Francisco, CA

69. Wang, Q., Soares, M.J., Fujii, H., and Knipp, G.T. (2000) Temporal and spatial patterns of expression of PPAR and RXR isoforms in the rat placenta. APS Eastern Regional Meeting, Parsippany, NJ.

70. Dai, G., Wang, D., Liu, B., Kasik, J.W., Müller, H., White, R.A., Hummel, G.S., and Soares, M.J. (2000) Three novel paralogs of the rodent prolactin gene family. 33th Annual Meeting of the Society for the Study of Reproduction, Madison, WI

71. Ain, R., Tash, J., and Soares, M.J. (2001) Trophoblast-derived cytokine prolactin-like protein-A: a regulator of uterine natural killer cells during the establishment of pregnancy. FASEB 2001, Orlando, FL

72. Sahgal, N., Dai, G., Lu, L., and Soares, M.J. (2001) Identification of cellular targets for a new member of the decidual prolactin gene family, prolactin-like protein-J. Pediatric Academic Societies Annual Meeting, Baltimore, MD

73. Kamei, T., Jones, S.R., Chapman, B.M., Beal, J.M., Tang, S., Lu, L., Dai, G., and Soares, M.J. (2001) Activation of the phosphatidylinositol 3-kinase/akt signaling pathway during trophoblast cell differentiation. 83th Annual Meeting of the Endocrine Society, Denver CO

74. Sahgal, N., Tang, S., Dai, G., Soares, M.J. (2001) Placental responses to fetal death: depletion of glycogen cells and upregulation of insulin-like growth factor binding protein-2 and nutrient transport protein messenger RNAs. 83th Annual Meeting of the Endocrine Society, Denver CO

75. Ain, R., Lu, L., Dai, G., and Soares, M.J. (2001) Targeted expression of prolactin-like protein-A to smooth muscle cells in transgenic mice. 83th Annual Meeting of the Endocrine Society, Denver CO

76. Dai, G., Lu, L., Tang, S., Sahgal, N., and Soares, M.J. (2001) Evaluation of placental/trophoblast cell phenotypes with a prolactin family DNA miniarray. 83th Annual Meeting of the Endocrine Society, Denver CO

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77. Rider, V., Dai, G., and Soares, M.J. (2001) Regulation of rat uterine stromal cell differentiation. 34th Annual Meeting of the Society for the Study of Reproduction, Ottawa, Canada

78. Müller, H., Soares, M.J., Jeschke, U., Reimer, T., Friese, K. (2001) Identification of a candidate natural killer cell receptor for prolactin-like protein-A. Annual Meeting of the European Placental Group, Sorrento, Italy

79. Wiemers, D.O., Ain, R., Shao, L.-J., Dai, G., and Soares, M.J. (2002) The mouse prolactin gene family locus. 84th Annual Meeting of the Endocrine Society, San Francisco, California.

80. Sahgal, N., Kent, L.N., Dai, G., and Soares, M.J. (2002) Experimental modulation of trophoblast stem cell and trophoblast giant cell phenotypes. 84th Annual Meeting of the Endocrine Society, San Francisco, California.

81. Takahashi, T., Lu, L., Ain, R., Alt, A., Li, C., Dai, G., Hashizume, K., Schuler, L.A., and Soares, M.J. (2002) A strategy for identifying bovine prolactin family interactions with target tissues. 35th Annual Meeting of the Society for the Study of Reproduction, Baltimore, Maryland

82. Dai, G., Peal, M.J., and Soares, M.J. (2002) Hepatomegaly and hepatic gene expression during pregnancy in the mouse. 35th Annual Meeting of the Society for the Study of Reproduction, Baltimore, Maryland

83. Alt, A., Dai, G., Peal, M.J., Ain, R., and Soares, M.J. (2002) Pregnancy-dependent splenomegaly and splenic gene expression. 35th Annual Meeting of the Society for the Study of Reproduction, Baltimore, Maryland

84. Ain, R., Dai, G., and Soares, M.J. (2002) Trophoblast cells invading the uterine mesometrial triangle possess a novel endocrine phenotype. 35th Annual Meeting of the Society for the Study of Reproduction, Baltimore, Maryland

85. Sahgal, N., Canham, L.N., and Soares, M.J. (2003) Fetal regulation of trophoblast cell invasion into the maternal uterine mesometrial vascular compartment. Annual Meeting of the Society for Pediatric Research, Seattle, Washington

86. Canham, L.N., Sahgal, N., Wolfe, M.W., and Soares, M.J. (2003) Selective involvement of the phosphatidylinositol 3-kinase/Akt signaling pathway in the regulation of trophoblast cell differentiation. 36th Annual Meeting of the Society for the Study of Reproduction, Cincinnati, Ohio

87. Ohboshi, S., Ain, R., Wiemers, D.O., and Soares, M.J. (2003) Migratory trophoblast cells express a newly identified member of the prolactin gene family: a putative regulator of maternal liver function. 36th Annual Meeting of the Society for the Study of Reproduction,

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Cincinnati, Ohio

88. Ain, R., Canham, L.N., and Soares, M.J. (2003) Migratory trophoblast cell fate: modulation by glucocorticoids. 9th International Federation of Placental Associations and 10th European Placental Group Meeting, Mainz, Germany

89. Casillian, A.J., Gonzalez, N.C., Ain, R., Soares, M.J., and Wood, J.G. (2004) Upregulation of heme oxygenase-1 and inducible nitric oxide synthase mediates microvascular acclimatization to systemic hypoxia. Annual FASEB Meeting, Washington, D.C.

90. Arroyo, J.A., Ain, R., and Soares, M.J. (2004) A simple in vivo approach to investigate the regulation of trophoblast cell invasion. 37th Annual Meeting of the Society for the Study of Reproduction, Vancouver, British Columbia, Canada

91. Ho-Chen, J.K., Bustamante, J.J., and Soares, M.J. (2004) Trophoblast cell responses to restricted oxygen. 37th Annual Meeting of the Society for the Study of Reproduction, Vancouver, British Columbia, Canada

92. Bustamante, J.J., Takahashi, T., Dai, G., and Soares, M.J. (2004) Prolactin-like protein-C binds to hepatocytes via a mechanism independent of the prolactin receptor. 37th Annual Meeting of the Society for the Study of Reproduction, Vancouver, British Columbia, Canada

93. Alam, S.M.K., Konno, T., Sahgal, N., Li, C., Lu, L., Canham, L.N., and Soares, M.J. (2004) Decidual cells produce a heparin-binding cytokine, prolactin-like protein-J: expression and biological targets. 37th Annual Meeting of the Society for the Study of Reproduction, Vancouver, British Columbia, Canada

94. Ohboshi, S. and Soares, M.J. (2004) Phosphatidylinositol 3-kinase/Akt signaling pathway and 14-3-3 ligand interactions modulate the endocrine phenotype of trophoblast cells. 37th

Annual Meeting of the Society for the Study of Reproduction, Vancouver, British Columbia, Canada

95. Konno, T., Alam, S.M.K., Dai, G., Lu, L., Wang, D., Dunmore, J., Godwin, A.R., and Soares, M.J. (2004) Decidual prolactin-related protein gene targeting: insights into expression and biological actions. 37th Annual Meeting of the Society for the Study of Reproduction, Vancouver, British Columbia, Canada

96. Sahgal, N. and Soares, M.J. (2004) Gestationally dependent invasion of trophoblast into the maternal uterine mesometrial compartment is regulated by fetal signals. 37th Annual Meeting of the Society for the Study of Reproduction, Vancouver, British Columbia, Canada

97. Truog, W.E., Xu, D., Mabry, S., Rezaiekhaligh, M., and Soares, M.J. (2005) Postnatal hypoxia and acinar lung development: analysis by microarray and histology microarray. Society for Pediatric Research, May.

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98. Ho-Chen, J.K. and Soares, M.J. (2005) Maternal adaptation to hypobaric hypoxia. 87th

Annual Meeting of the Endocrine Society, San Diego, CA.

99. Alam, S.M.K., Sahgal, N., and Soares, M.J. (2005) Identification of new members of the rat prolactin gene family. 87th Annual Meeting of the Endocrine Society. San Diego, CA.

100.Bustamante, J.J. and Soares, M.J. (2005) Pregnancy and lactation modulate hepatic and splenic growth and gene expression. 87th Annual Meeting of the Endocrine Society, San Diego, CA.

101.Alam, S.M.K., Crowley, A.R., Ain, R., and Soares, M.J. (2006) Regulation of pregnancy-dependent adaptations to hypoxia. 39th Annual Meeting of the Society for the Study of Reproduction, Omaha, Nebraska.

102.Bustamante, J.J., Copple, B., and Soares, M.J. (2006) Pregnancy-dependent hepatomegaly is associated with increased expression of the nephroblastoma overexpressed gene (NOV/CCN3). 39th Annual Meeting of the Society for the Study of Reproduction, Omaha, Nebraska.

103.Canham, L.N. and Soares, M.J. (2006) Regulation of steroidogenesis in differentiating trophoblast giant cells: a role for the phosphatidylinositol 3-kinase/akt signaling pathway. 39th Annual Meeting of the Society for the Study of Reproduction, Omaha, Nebraska.

104.Ho-Chen, J.K., Ain, R., and Soares, M.J. (2006) Adaptations to maternal hypoxia in the mouse and rat during late gestation. 39th Annual Meeting of the Society for the Study of Reproduction, Omaha, Nebraska.

105.Konno, T., Rempel, L.A., Arroyo, J.A., and Soares, M.J. (2006) Pregnancy failure in the Brown Norway rat is associated with impaired trophoblast invasion. 39th Annual Meeting of the Society for the Study of Reproduction, Omaha, Nebraska.

106.Rempel, L.A., Konno, T., and Soares, M.J. (2006) Placental insufficiency in the Brown Norway rat. 39th Annual Meeting of the Society for the Study of Reproduction, Omaha, Nebraska.

107.Konno, T., Rempel, L.A., Larson, M., and Soares, M.J. (2007) Establishment of pregnancy in the Brown Norway rat: origins of its distinct placentation. International Federation of Placental Associations, Kingston, Ontario, Canada.

108.Rempel, L.A., Konno, T., Larson, M., and Soares, M.J. (2007) Impact of maternal environment and embryonic genotype on placentation. International Federation of Placental Associations, Kingston, Ontario, Canada.

109.Canham, L.N., Sahgal, N., and Soares, M.J. (2007) Discovery of genes differentially regulated during trophoblast cell differentiation. International Federation of Placental

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Associations, Kingston, Ontario, Canada.

110.Rosario, G.X. and Soares, M.J. (2007) Hypoxia-activated endovascular trophoblast cell invasion. International Federation of Placental Associations, Kingston, Ontario, Canada.

111.Alam S.M.K., Konno, T., Sahgal, N., and Soares, M.J. (2007) Prolactin-like protein-J: expression and biological targets. International Federation of Placental Associations, Kingston, Ontario, Canada.

112.Rumi, M.A.K., Canham, L.N., Asanoma, K., Gowda, S., and Soares, M.J. (2008) A differentiation state-specific promoter for tracking trophoblast cell decisions. 6th

International Society for Stem Cell Research Annual Meeting, Philadelphia, PA

113.Canham, L.N., Rumi, M.A.K., Asanoma, K., and Soares, M.J. (2008) Cell lineage decisions in the differentiation of rat trophoblast stem cells: involvement of the phosphatidylinositol 3-kinase signaling pathway and fos-like antigen 1. 6th International Society for Stem Cell Research Annual Meeting, Philadelphia, PA

114.Asanoma, K., Lee, D.-S., and Soares, M.J. (2008) Isolation of stem cells from rat blastocysts possessing the capacity to differentiate along the trophoblast cell lineage. 6th International Society for Stem Cell Research Annual Meeting, Philadelphia, PA

115.Konno, T., Crowley, A.R., Rempel, L.A, Ho-Chen, J.K., Rumi, M.A.K., Butler, N.E., Asanoma, K., Alam, S.M.K., and Soares, M.J. (2008) Placentation in the rat is modulated by regulatory information on Chromosome 17. Gordon Research Conference-Reproductive Tract Biology, Proctor Academy, Andover, New Hampshire.

116.Lee, D.-S., Rumi, M.A.K., Konno, T., and Soares, M.J. (2008) Trophoblast-specific gene transfer in the rat using lentiviral vector delivery. Gordon Research Conference-Reproductive Tract Biology, Proctor Academy, Andover, New Hampshire.

117.Chakraborty, D., Konno, T., and Soares, M.J. (2008) Uterine natural killer cells: homing and effects on rat placentation. Gordon Research Conference-Reproductive Tract Biology, Proctor Academy, Andover, New Hampshire.

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CURRICULUM VITAE Dr. Michael J. Soares · CURRICULUM VITAE Dr. Michael J. Soares Personal...

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