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Relue –Curriculum Vitae
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CURRICULUM VITAE
I. PERSONAL INFORMATION
NAME POSITION TITLE
Patricia A. Relue, Ph.D. Professor, Department of Bioengineering
ADDRESS WORK: ADDRESS HOME:
University of Toledo Department of Bioengineering 1610 N. Westwood Avenue 5062 Nitschke Hall, MS 303 Toledo, OH 43606 (419) 530-8098 (phone) (419) 530-8076 (FAX) [email protected]
2437 Barrington Drive Toledo, OH 43606 (419) 534-4568 (phone) (419) 345-5142 (cell) [email protected]
II. EDUCATION
YEAR(s) DEGREE INSTITUTION AND LOCATION FIELD OF STUDY
1994 Ph.D. The University of Michigan, Ann Arbor, MI Chemical Engineering
1990 M.S. The University of Michigan, Ann Arbor, MI Engineering
1988 B.S. The University of Toledo, Toledo, OH Magna Cum Laude, with Honors
Chemical Engineering
III. APPOINTMENTS AND EXPERIENCE
Date Institution and position University of Toledo unless otherwise noted
July 1, 2014 – present; Aug. 2000 – May 2001; May 1999 – Nov. 1999;
Undergraduate Program Director, Department of Bioengineering
April 2014 – present Professor, Department of Bioengineering
Mar. 2002 – Aug. 2010 Graduate Program Director, Department of Bioengineering
May 2001 – Dec. 2001 New Jersey Institute of Technology, Newark, NJ Visiting Professor (Sabbatical Leave, Department of Electrical and Computer Engineering
April 1999 – April 2014 Associate Professor, Department of Bioengineering
July 1996 – April 1999 Assistant Professor, Department of Bioengineering
Mar. 1995 – 2003 Medical College of Ohio, Toledo, OH Adjunct Assistant Professor, Department of Pathology
Nov. 1993 – July 1996 Assistant Professor, Department of Chemical Engineering
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IV. TEACHING
Courses taught in undergraduate and graduate curricula:
Course Title
ES 100 First Year Information (FYI)/Orientation
ES 110 Creativity and Problem Solving
CHE 201 Introduction to Chemical Engineering I
CHE 202 Introduction to Chemical Engineering II
CHE 211 Chemical Engineering I - Fluid Mechanics
CHE 317 Unit Operations Laboratory II
CHE 340 Applied Analysis
CHE 507/707 Chemical Engineering Seminar
BIOE 1000
BIOE 1010
Orientation & Introduction to Bioengineering*
Professional Development
BIOE 2100 Bioengineering Thermodynamics*
BIOE 2200 Biomaterials*
BIOE 3400 Biotransport Phenomena*
BIOE 3500 Bioprocessing Laboratory**
BIOE 4740/5740 Tissue Engineering*
BIOE 5110/7110 Principles of Bioengineering (transport)*
BIOE 5120/7120 Bioengineering Laboratory
BIOE 572/772 Introduction to Biomaterials Engineering*
BIOE 6710/8710 Tissue Engineering*
BIOE 5980/7980 Biophotonics*
BIOE 5980/7980 Research Methods for Bioengineers* * course developed by P. Relue; ** course developed with S.T. Sharfstein
Advanced Degree Candidates:
Mr. Peng Zhang, Ph.D candidate, Bioengineering Program
Ph.D. Graduates:
Defense Student and dissertation title
Dec. 2015 Ms. Kelly Marbaugh, “Theoretical and experimental studies on simultaneous-isomerization and reactive-extraction followed by back-extraction based process for furan production via a ketose sugar intermediate from hemicelluose hydrolysate (co-advisor with S. Varanasi)
Jan. 2015 Mr. Heng Shao, “Efficient production of “platform” organic acids from lignocellulosic and algal biomass carbohydrates, (co-advisor with S. Varanasi and S. Viamajala)
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Sept. 2012 Mr. Bin Li, “Innovative Methods for Improving Biomass Sugars Utilization,” (co-advisor with S. Varanasi)
Nov. 2010 Mr. Dawei Yuan, “Strategies for Efficient Fermentation of Biomass Derived Glucose and Xylose to Ethanol using Naturally Occurring Saccharomyces cerevisiae,” (co-advisor w/ S. Varanasi)
June 2006 Mr. Ye Yuan, “Polarized Spectra for Characterization of Tissue Metabolic State”
May 2001 Mr. Biao Cheng, “Study on the Inhibition of E. coli lac Operon Gene Expression by Antigene Oligonucleotides,” (co-advisor w/ R. Fournier)
July 1997 Mr. Jin Yuan, “Photodynamic Therapy: Mathematical Modeling and Experimental Studies”
M.S. Graduates:
Defense Student and thesis/project title
Aug. 2011 Mr. Alex Fitzthum, MSBS in Biomedical Sciences, “Growth Requirements and Metabolic End Products of Bifidobacteria,” Scholarly Project.
Apr. 2010 Ms. Susie Shi, “Development of experimental protocols for a heterogeneous bioscaffold-chondrocyte construct with application to a tissue engineered spinal disc,” (co-advisor w/ A. Nadarajah)
Dec. 2007 Ms. Silpa Chelikani, “Effects of Additives and Media Formulations in Shifting the Equilibrium of Xylose Isomerization Catalyzed by an Immobilized Enzyme System.”
Dec. 2000 Ms. Janel Lanphere, “Spectraphotometric Characteristics of Chromophores Found in Melanoma.”
Dec. 2000 Mr. Amit Nimunkar, “Wavelet and Statistical Analysis of Multispectral Skin Lesions.”
May 2000 Mr. Jonathan Schisler, “Effect of Antigene Triplex-Forming Oligonucleotides on Gene Expression.”
Dec. 1999 Ms. Kristin Smith, “Autofluorescence Imaging as a Method of Differentiation between Nevus, Dysplastic Nevus, and Malignant Melanoma.”
Aug. 1999 Mr. John Fisher, “Evaluation of E. coli on Glucose: Kinetic Parameter Estimations via Electrolytic Respirometry.”
Aug. 1999 Ms. Kelly Goodwin, “Imaging of Melanoma Cells in Monolayer cultures and Three-Dimensional Configurations.”
Aug. 1999 Ms. Jenae Johnson, “Optical Imaging of Melanoma Cells in 2-D and 3-D Culture with Agar Matrices.”
Aug. 1999 Mr. Shaoyong Chen, “Development of a Model System for Triplex-Oligonucleotide Blocked Gene Expression in E. coli.”
Feb. 1999 Ms. Xinhua Wang, “Calculation of the Parameters for E. coli Growth on Glucose.”
Aug. 1998 Ms. Kristen Eingle, M.S. Bioengineering (co-advised with R. Fournier), “Development of a Plasmid System for the Study of Oligonucleotide Binding.”
Dec. 1997 Ms. Sangita Sunduram, “Antisense Oligonucleotides: Use in Mammalian Cells.”
Aug. 1997 Mr. David Decamp, “A Molecular Modeling Investigation of Oligonucleotides Binding to Duplex DNA in the lac operon region of E. coli.”
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June 1997 Mr. Deepak Keni, “Mathematical Modeling of Antibody Targeted Photolysis.”
Mar. 1997 Ms. Ming Zhang, “Pharmacokinetic Modeling of Photosensitizer Distribution in the Rat.”
Undergraduate Research/Independent Study Projects Directed:
Date Student, affiliation, and project
Jan – May 2017
Mr. Jeremy Schreur, B.S. candidate in Chemical Engineering, NSF REU Fellow, “Large scale implementation of SIRE on AFEX-pretreated biomass hydrolysate.”
May – Aug 2016
Mr. Aaron McGinnis, B.S. candidate in Chemical Engineering, UT-OUR First Year Summer Research Experience, “Planning, Designing, and Building Infrastructure for the Sofia Quintero Art and Cultural Center.”
May – Aug 2016
Ms. Therese Orsagos, B.S. candidate in BIOE, NSF REU Fellow, “Establishing isomerization conditions that allow efficient separation of xylulose from mixed sugar hydrolysates.”
May – Aug 2016
Mr. Josh Robles, B.S. candidate in BIOE, NSF REU Fellow, “Isomerization and reactive extraction conditions for efficient separation of ketose sugars from biomass hydrolysates.”
May – Aug 2016
Mr. Jeremy Schreur, B.S. candidate in Chemical Engineering, NSF REU Fellow, “Comparison of SIRE-BE on simulated sugars and biomass hydrolysates.”
May – Aug 2016
Mr. Clinton Kulwicki, B.S. candidate in Chemical Engineering, NSF REU Fellow, “Varying pH, Volume Ratio, and Temperature of Glucose Fructose Solution During Back-Extraction to Achieve High Concentration and Purity of Fructose.”
Jan – May 2015
Mr. Corey Howe, B.S. candidate in BIOE, UT-OUR Academic Year Research Program, “Identification of necessary genes for the de novo biosynthesis of Dluciferin in fireflies.”
May – Aug 2014
Mr. Robert Ariss, B.S. candidate in BIOE, NSF REU, “Effect of volume ratio on reactive extraction efficiency of biomass sugars.”
May – Aug 2014
Ms. Rachel Wagner, B.S. candidate in BIOE, OUR-UT Undergraduate Research Programs, “Equilibrium reactive-extraction of biomass sugars: Evaluation of binding constants for process optimization.”
May – Aug 2014
Ms. Rebecca Shaheen, B.S. candidate in BIOE, UT-OUR First Year Summer Research Experience, “Extraction of Ketose from Aldose Sugars Using Simultaneous Isomerization and Reactive Extraction.”
May – July 2014
Ms. Lauren Spyker, B.S. candidate in BIOE, Independent study, “Staged stripping for separation of aldose and ketose sugars.”
May – Aug 2013
Mr. Vince Meyer, B.S. candidate in BIOE, UT Sullivan Honor’s Research Fellowship, “Improving sugar extraction and selectivity during simultaneous isomerization and reactive extraction by modification of the organic phase composition.”
May – Aug 2013
Mr. Jon Wimer, B.S. candidate in BIOE, OUR-UT Undergraduate Research Programs, “High Yield Production of Ketose Sugars Through Reactive Extraction: Evaluation of Mixed Sugar Extraction and Separation.”
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May – Aug 2013
Ms. Alexis Schwann, B.S. candidate in BIOE, UT-OUR First Year Summer Research Experience, “Measurement of Sugar-Boronic Acid Binding Affinity and Development of a Mathematical Binding Model.”
Aug 2012 – May 2013
Mr. Jeffrey Beagle, B.S. candidate in BIOE, independent study project, “Design of a large-scale sugar purification system.”
Aug 2012 – May 2013
Ms. Rachel Beeson, B.S. candidate in BIOE, independent study project, continuation of summer research project, “Simultaneous Isomerization and Reactive Extraction of Biomass Sugars for High yield Production of Fructose Sugar.”
May – Aug 2012
Mr. David Taylor, B.S. candidate in BIOE, UT-OUR Undergraduate Summer Research and Creative Activity Fellowship, “Simultaneous Isomerization and Reactive Extraction of Biomass Sugars for High yield Production of Ketose Sugars.”
May – Aug 2012
Mr. Kang Ke, B.S. candidate in BIOE, Summer Co-op Rotation, “Detoxification of Biomass Sugars for Succinic Acid Production.”
May – Aug 2012
Ms. Rachel Beeson, B.S. candidate in BIOE, Presidential Scholar Co-op Rotation, “Simultaneous Isomerization and Reactive Extraction of Biomass Sugars for High yield Production of Fructose Sugar.”
Oct 2011 – May 2012
Ms. Amber Hall, B.S. candidate in BIOE, UT STARS Fellow, “Synthesis of boronic acid compounds with preferential binding to xylose.”
May – Aug 2011
Ms. Amber Hall, B.S. candidate in BIOE, UT-OUR Undergraduate Summer Research and Creative Activity Fellowship, “ ‘Phase-switching’ to enhance isomerization of biomass sugars.”
Jan – May 2011
Ms. Amber Hall, B.S. candidate in BIOE, UT-OUR STARS Fellow, “Partitioning of boronic acids between aqueous and organic phases as a function of pH.”
May – Aug 2010
Mr. Zachary Reaver, B.S. candidate in BIOE, UT-OUR Undergraduate Summer Research and Creative Activity Fellowship, “Evaluation of Bipolar Membrane Electrodialysis for the Recovery of Borate from Biomass Sugars.”
May – Aug 2010
Mr. Alex Fitzthum, B.S. graduate in BIOE, “Microplate assay development for determining urease activity with phenol red.”
May – Aug 2010
Ms. Sasha Aquino, B.S. candidate in BIOE, UT Undergraduate Summer Research and Creative Activity Fellowship, “Isolation of urease enzyme from natural sources: purity and cost analysis for use in production of ethanol from biomass.”
May – Aug 2010
Ms. Mariem Amami, B.S. candidate in BIOE, “Determination of urease activity and recovery from jack beans using acetone extraction.”
May – Aug 2009
Ms. Kelly Marbaugh, B.S. graduate in BIOE, Summer Research, “Method for producing and purifying recombinant bacterial urease.”
Aug – Dec 2008
Mr. Steven Donnelly, B.S. candidate in BIOE, independent study, “Purification and spectrophotometric quantification of urease from pigeon peas.”
Aug – Dec 2008
Ms. Nisha Patel, B.S. candidate in BIOE, independent study, “Testing and development of urease quantification assays.”
Jan – Aug 2008
Ms. Mariem Amami, B.S. candidate in BIOE, Undergraduate Work Study, “Isolation of urease from pigeon peas.”
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May – Aug 2003
Ms. Samantha Keevey, B.S. candidate in BIOE, UT Undergraduate Summer Research and Creative Activity Fellowship, “Absorption and scattering properties of tissue engineered skin and melanoma tissue.”
May – Aug 2001
Mr. Rob Criss, B.S. candidate in BIOE, Research Co-Op rotation, “Measurement of calcium signaling in melanoma and nerve-like cells.”
May – Aug 2001
Mr. Dan Miller, B.S. candidate in BIOE, UT Undergraduate Summer Research and Creative Activity Fellowship, “Evaluation of Autofluorescence Characteristics of Melanoma Cells and Tissue Engineered Skin Equivalents.”
May 2000 – Dec 2001
Ms. Kristen Salzgeber, B.S. candidate in BIOE, UT Sullivan Honor’s Undergraduate Research Fellowship, “Measurement of intracellular calcium in A9-L cells.”
May – Dec 2000
Mr. Ryan Webb, B.S. candidate in BIOE, independent study, “Measurement of enzyme activity of immobilized and free -galactosidase.”
Jan – Aug 2000
Mr. Jeremy Heffner, B.S. candidate in BIOE, UT Sullivan Honor’s Undergraduate Research Fellowship, “Evaluation of fluorescent dyes for the measurement of intracellular calcium.”
Aug 1999 – May 2000
Ms. Kara Buehrer, B.S. candidate in BIOE, independent study, “Culture of melanoma tumorlets.”
Jan – Aug 1999
Ms. Sybille Thies, B.S. candidate in BIOE, independent study, “Respirometry: A guide to using the respirometer.”
May 1997 – Dec 1999
Mr. Kevin Biddell, B.S. candidate in BIOE, independent study and UT Honors Undergraduate Summer Research Fellowship, “Using Electrolytic Respirometry to Measure the Biodegradation Kinetics of Glucose in E. coli Cultures.”
Jan – May 1998
Mr. Wes Huff, B.S. candidate in ChE, independent study, “Setup and verification of an electrolytic respirometry system.”
June – Sept 1997
Ms. Kristen Given, B.S. candidate in ChE, UT Honors Undergraduate Summer Research Fellowship, “Effect of pH on the growth kinetics of Helicobacter pylori.”; continued with the measurement of the kinetics of -galactosidase expression in E. coli.”
Mar – May 1996
Mr. Chee Hong Chat, B.S. candidate in ChE, independent study, “Effect of Stir Rate on R3230AC Tumor Cells in a Sealed Chamber.”
June 1995 – June 1997
Mr. Lawrence Zimmerman, B.S. candidate in Che, UT Honors Undergraduate Summer Research Fellowship, “Intracellular Concentration of Calcium as a Measure of Cell Response;” continued with measurement of singlet oxygen consumption in monolayers of tumor cells.
Thesis and Dissertation Committees:
Date Student Degree Advisor
Mar 2017 Mr. Mohammadmatin Hanifzadeh PhD proposal defense (ChEE) S. Viamajala
Dec 2016 Mr. Suren Uswatta MS Bioengineering A. Jayasuriya
April 2016 Mr. Agastaswar Vadlamani PhD Chemical Engineering S. Viamajala
April 2015 Mr. Siamak Alipour PhD Chemical Engineering S. Varanasi
Feb 2014 Ms. Venkata Mantripragada PhD Biomedical Engineering A. Jayasuriya
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July 2013 Mr. Nathan Reaver MS Bioengineering B. Cameron
Mar 2013 Ms. Maggie Ditto MS Bioengineering E. Yildirim-Ayan
Mar 2013 Mr. Brandon Clarke MS Bioengineering B. Cameron
May 2012 Ms. WenWen Zhang MS Chemical Engineering S. Varanasi
Dec 2011 Mr. Huan Zhou PhD Biomedical Engineering S. Bhaduri
June 2011 Ms. Julie Matheny MS Bioengineering L. Berhan
Apr 2011 Mr. Mark Skopin PhD Bioengineering S. Molitor
Mar 2011 Ms. Carrie Baker M.S. Bioengineering L. Berhan
Mar 2011 Mr. Anthony Webb PhD proposal defense B. Cameron
July 2010 Mr. Varun Sendamangalem M.S. Bioengineering D.-S. Kim
June 2010 Ms. Andrea Pilon M.S. Bioengineering V. Goel
July 2009 Mr. Huan Zhou M.S. Bioengineering S. Bhaduri
Dec. 2008 Mr. Prasenjit Das Ph.D. Bioengineering R. Fournier
June 2008 Ms. Kripa Rao Ph.D. Chemical Engineering S. Varanasi
Dec 2007 Ms. Suneeth Mohan M.S. Bioengineering V. Goel
Apr 2007 Mr. Frank Licari M.S. Bioengineering S. Molitor
Oct 2006 Mr. Jian Zhou M.S. Bioengineering S. Molitor
Dec 2005 Ms. Yanfang Li Ph.D. Bioengineering B. Cameron
Dec 2005 Mr. Mingie Tong Ph.D. Bioengineering S. Molitor
July 2005 Ms. Archana Bhat M.S. Bioengineering R. Fournier
Apr 2005 Ms. Rebecca Long M.S. Bioengineering V. Goel
Jan 2004 Mr. Deepan Vora M.S. Bioengineering S. Molitor
Oct 2003 Mr. Mohammad Siraj Ph.D. candidate Bioengineering B. Cameron
May 2003 Ms. Ajaina Nezhuvingal M.S. Bioengineering B. Cameron
May 2003 Mr. Kevin Biddell Ph.D. candidate Bioengineering J. Johnson
Apr 2003 Mr. Rob Criss M.S. candidate Bioengineering P. Relue
Apr 2003 Ms. Libo Xu Ph.D. Med. & Biol. Chemistry J. Slama
May 2002 Ms. Kristin Smith Ph.D. candidate Bioengineering P. Relue
Apr 2001 Mr. Jinghong Li Ph.D. Bioengineering J. Johnson
Jan 2001 Ms. Rui Zhou Ph.D. Bioengineering S. Sharfstein
Jan 2001 Mr. Gang Liu M.S. Bioengineering B. Cameron
June 2000 Ms. Katie McNeeley M.S. Bioengineering S. Sharfstein
Aug 2000 Mr. Zhe Sun Ph.D. Bioengineering S. Sharfstein
Nov 1999 Mr. Saurabh Lauria Ph.D. candidate Bioengineering A. Dhawan
Oct 1999 Mr. Sachin Patwardhan Ph.D. candidate Bioengineering A. Dhawan
Oct 1999 Ms. Aiying Sun Ph.D. candidate Bioengineering P. Relue
June 1999 Ms. Xinyan Huang Ph.D. candidate Biology R. Komuniecki
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May 1999 Ms. Abeer El-Gharbauy Ph.D. candidate Med & Biol Chem
C. Hinman
Apr 1998 Mr. Amar Raheja Ph.D. Bioengineering A. Dhawan
Nov 1996 Dr. Guodong Chen Ph.D. Chemical Engineering R. Fournier & S. Varanasi
Aug 1996 Mr. Faming Shen M.S. Computer Sci & Eng J. Estell
May 1996 Mr. A. Ryan Baker M.S. Chemical Engineering R. Fournier
V. RESEARCH & PUBLICATIONS
Patents:
S. Varanasi, K. Rao, P. Relue, and D. Yuan, “System for Simultaneous Isomerization and Fermentation of Sugars,” US Doc ID 20130330800 A1, US. Pat. No. 9,528,104 B2 issued December 27, 2016.
S. Varanasi, P. Relue, B. Li, “Aldose-ketose transformation for separation and/or chemical conversion of C6 and C5 sugars from biomass materials,” US Doc ID 20130074397 A1, US Pat. No. 9,242,222, issued January 26, 2016.
S. Alipour, B. Li, S. Varanasi, P. Relue, and S. Viamajala, “Methods for high yield production of furans from biomass sugars at mild operating conditions,” US Doc ID 20160281120, published Sept 29, 2016.
H. Shao, A. Vadlamani, S. Viamajala, S. Varanasi, and P. Relue, “Enzymatic digestion of microalgal biomass for lipid, sugar and protein recovery,” US patent application 14/913896, US Doc ID 20160222421, published August 4, 2016.
S. Varanasi, P. Relue, B. Li, “Aldose-ketose transformation for separation and/or chemical conversion of C6 and C5 sugars from biomass materials,” US Appl No. 14/969899, US Doc ID 20160096857, April 7, 2016
S. Varanasi, K. Rao, P. Relue, and D. Yuan, “Methods of fermentation of xylose and hexose sugars,” US Doc ID 20100285552, US Pat No. 8,507,232, issued August 13, 2013.
Y. Yuan, P.A. Relue, and B.D. Cameron, “Method to Monitor Metabolic Changes in Living Cells Using Endogenous Polarization-Sensitive Fluorescence,” U.S. Provisional Patent Application Serial No. 60/843,183 filed Sept. 8, 2006; US Ser. No. 11/899,675 filed Sept. 6, 2007.
Refereed Journal Publications:
B. Li, P. Zhang, S. Varanasi, and P. Relue, “New route for enabling utilization of C5 and C6 sugars of lignocellulosic biomass by native S. cerevisiae for ethanol production,” in preparation for Bioresource Technology.
H. Shao, S. Varanasi, S. Viamajala, and P. Relue, “Detoxification of dilute-acid and ionic-liquid pretreated wheat straw hydrolysate to improve succinic acid fermentation,” in preparation for Biofuels, Bioproducts & Biorefining.
S. Alipour, H. Omidvarborna, S. Viamajala, P. Relue and S. Varanasi, "Enzymatic and catalytic hybrid method for levulinic acid synthesis from biomass sugars." Journal of Cleaner Production 143: 490-496, 2017.
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S. Alipour, S. Viamajala, P. Relue, and S. Varanasi, “High Yield 5-(hydroxymethyl)furfural production from biomass sugars under facile reaction conditions: a hybrid enzyme- and chemi-catalytic technology,” Green Chemistry, 18:4990-4998, 2016.
S. Alipour, H. Omidvarborna, S. Viamajala, P. Relue and S. Varanasi, "High concentration levulinic acid production from corn stover." RSC Advances 6(112): 111616-111621, 2016.
B. Li, S. Varanasi, and P. Relue, “High yield aldose-ketose transformation for isolation and facile conversion of biomass sugar to furan,” Green Chemistry, 15 (8): 2149 – 2157, 2013.
B. Li, P. Relue, and S. Varanasi, “Simultaneous isomerization and reactive extraction of biomass sugars for high yield production of ketose sugars,” Green Chemistry, 14:2436-2444, 2012.
D. Yuan, K. Rao, S. Varanasi, and P. Relue, “A viable method and configuration for fermenting biomass sugars to ethanol using native Saccharomyces cerevisiae,” Bioresource Technology, 117:92-98, 2012.
D. Yuan, K. Rao, P. Relue, and S. Varanasi, “Fermentation of biomass sugars to ethanol using native industrial yeast strains,” Bioresource Technology, 102(3):3246–3253, 2011.
K. Rao; S. Chelikani; P. Relue; and. S. Varanasi, “A Novel technique for Optimizing the Simultaneous-Isomerization-and-Fermentation (SIF) Approach of Converting Xylose to Ethanol,” Applied Biochemistry and Biotechnology, 146(1-3):101-117, 2008.
Y. Yuan and P. Relue, “Enzymatic degradation of human skin dermis revealed by fluorescence and reflectance spectroscopy,” Optics Express, 16(13):9857-9868, June 20, 2008.
Y. Yuan, Y. Li, B.D. Cameron, and P.A. Relue, “Fluorescence anisotropy of cellular NADH as a tool to study different metabolic properties of human melanocytes and melanoma cells,” IEEE Journal of Selected Topics in Quantum Electronics, 13(6, pt 1):1671-1679, Nov/Dec 2007.
S.V. Patwardhan, A.P. Dhawan, and P.A. Relue, “Monte Carlo Simulation of Light-Tissue Interaction: Three-Dimensional Voxel Based Simulation for Trans-Illumination-Based Imaging of Skin Lesions,” IEEE Transactions on Biomedical Engineering, 52(7):1227-1236, July 2005.
S.V. Patwardhan, A.P. Dhawan, and P.A. Relue, “Classification of Melanoma Using Tree-Structured Wavelet Transforms,” Computer Methods and Programs in Biomedicine, 72(3):223-239, Nov 2003.
B. Cheng, R.L. Fournier, P.A. Relue, and J. Schisler, “An experimental and theoretical study of the inhibition of Escherichia coli lac operon gene expression by antigene oligonucleotides,” Biotechnology and Bioengineering, 74(3):220-229, 2001.
B. Cheng, R.L. Fournier, and P.A. Relue, “The Inhibition of Escherichia coli lac Operon Gene Expression by Antigene Oligonucleotides – Mathematical Modeling,” Biotechnology and Bioengineering, 70(4):467-472, 2000.
J. Yuan, P.A. Mahama-Relue, R.L. Fournier, and J. Hampton, “Mathematical Model Predictions of Tissue Oxygenation and Singlet Oxygen Generation During Photodynamic Therapy,” Radiation Research, 148:386-394, 1997.
G. Chen, R.L. Fournier, S. Varanasi, and P.A. Mahama-Relue, “Helicobacter pylori Survival in Gastric Mucosa by Generation of a pH Gradient,” Biophysical Journal, 73(2):1081-1088, 1997.
P.A. Mahama and J.J. Linderman, “Monte Carlo Simulations of Membrane Signal Transduction Events: Effect of Receptor Blockers on G-Protein Activation,” Annals of Biomedical Engineering, 23:299-307, 1995.
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P.A. Mahama and J.J. Linderman “A Monte Carlo Study of the Dynamics of G-Protein Activation,” Biophysical Journal, 67:1345-1357, 1994.
P.A. Mahama and J.J. Linderman “Calcium Signaling in Individual BC3H1 Cells: Speed of Calcium Mobilization and Heterogeneity,” Biotechnology Progress, 10:45-54, 1994.
Book Chapters:
P.A. Relue, “Krogh Tissue Model of Tissue Oxygenation during Photodynamic Therapy,” Honorary Volume for Prof. D.D. Raftopoulos, Proceedings of the Symposium on Recent Advances in Mechanics, July 10-12, 1998, Department of Civil Engineering, Democritus University of Thrace, Greece, p. 110-124.
J.J. Linderman, P.A. Mahama, K.E. Forsten, and D.A. Lauffenburger, “Diffusion and Probability in Receptor Binding and Signaling,” Advances in Chemical Engineering, vol. 19, 1994, Academic Press, San Diego, CA, James Wei, Editor-in-Chief.
Conference Papers:
S.V. Patwardhan, A.P. Dhawan, and P.A. Relue, “Multi-Spectral Light Tissue Interaction Modeling for Skin Lesion Imaging,” 25th Proceedings of the Annual International Conference – IEEE EMBS, 2003, vol. 2:1019-1022.
S.V. Patwardhan, A.P. Dhawan, and P.A. Relue, “Wavelength Selection for Multi-Spectral Imaging of Skin Lesions,” Proc. IEEE 29th Annual Northeast Bioengineering Conference, 2003, p. 327-328.
S.V. Patwardhan, A.P. Dhawan, and P.A. Relue, “Tree structured wavelet transform signature for classification of melanoma,” SPIE Proceeding on Medical Imaging 2002: Image Processing p. 1085-1091, 2002.
A.J. Nimunkar, A.P. Dhawan, P.A. Relue, and S.V. Patwardhan, “Wavelet and statistical analysis for melanoma classification,” SPIE Proceeding on Medical Imaging, (4684-156) S16, February 2002.
S.T. Sharfstein and P.A. Relue, “Biotechnology and Bioprocessing Laboratory for Chemical Engineering and Bioengineering, Proceedings of the 2001 ASEE Annual Conference & Exposition, June 2001.
J.A. Hampton, P.A. Mahama, R.L. Fournier, and J.P. Henning, “Photodynamic Therapy: Computer Modeling of Diffusion and Reaction Phenomena,” SPIE Proceedings, vol. 2675, January 1996.
Conference presentations and posters: (FIRST AUTHOR IS PRESENTER)
P. Zhang, S. Varanasi, and P. Relue, “Simultaneous isomerization and reactive extraction followed by back extraction of sugars from biomass hydrolysate for high purity and yield of xylulose,” submitted to the ACS 21st Annual Green Chemistry and Engineering Conference, Reston, VA, June 13-15, 2017.
P. Zhang, S. Varanasi, and P. Relue, “New route of lignocellulosic biomass sugars fermentation to ethanol by native Saccharomyces cerevisiae,” 8th Annual Midwest Graduate Research Symposium, March 25, 2017.
S. Alipour, R. Beeson, S. Varanasi, P. Relue and S. Viamajala, “High-Yield Conversion of Glucose to 5-Hydroxymethylfurfural (HMF) Under Mild Reaction Conditions,” AICHE Annual Meeting, paper 431332, November 8-13, 2016, Salt Lake City, UT.
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P. Zhang, S. Varanasi and P. Relue, “Isolation of Ketose Sugars from Mixed Sugar Solutions Using Simultaneous-Isomerization-and-Reactive-Extraction (SIRE), Followed by Back-Extraction (BE)” 38th Symposium of Biotechnology for Fuels and Chemicals, Poster M21, April 25-28, 2016, Baltimore, MD.
R. Gogar, S. Viamajala, P. Relue, S. Varanasi, “Sustainable production of HMF from biomass hydrolysates,” Abstract ID: 2488486, ACS 20th Annual Green Chemistry & Engineering Conference, Portland, Oregon, June 14-16, 2016.
R. Gogar, S. Varanasi, P. Relue, “High yield production of furans from biomass hydrolysates using a hybrid enzyme and chemocatalytic technology,” 2016 NSF SBIR/STTR Phase II Grantee Conference, June 5-8, Atlanta, GA.
P. Relue, S. Varanasi, and S. Viamajala, “High yield production of furans from biomass hydrolysates using a hybrid enzyme- and chemo-catalytic technology,” Center for the Sustainable Use of Greenhouse Gases, Industry Planning Conference, June 24-25, 2015.
K. Marbaugh, S. Varanasi, P. Relue, and S. Viamajala, “High yield production of furans from biomass hydrolysates using a hybrid enzyme- and chemo-catalytic technology,” November 4, 2014, Poster, Center for the Sustainable Use of Greenhouse Gases, Industry Planning Conference, June 24-25, 2015.
S. Varanasi, S. Alipour, S. Viamajala, and P. Relue, “High yield production of furans from biomass hydrolyzates using a hybrid enzyme- and chemo-catalytic technology,” AICHE Annual Meeting, paper 388355, November 16-21, 2014, Atlanta, GA.
P. Relue, S. Varanasi, and S. Viamajala, “High yield production of furans from biomass hydrolysates using a hybrid enzyme- and chemo-catalytic technology,” November 4, 2014, Presentation, Center for the Sustainable Use of Greenhouse Gases Symposium, Ohio State University, Columbus, OH.
K. Marbaugh, S. Varanasi, P. Relue, and S. Viamajala, “High yield production of furans from biomass hydrolysates using a hybrid enzyme- and chemo-catalytic technology,” November 4, 2014, Poster, Center for the Sustainable Use of Greenhouse Gases Symposium, Ohio State University, Columbus, OH.
K. Marbaugh, B. Li, S. Varanasi, and P. Relue, “Xylulose to furfural: a mathematical modeling assessment of a new route to produce a high yield of furan,” 36th Symposium of Biotechnology for Fuels and Chemicals, Paper 4.04, April 28-May 1, 2014, Clearwater Beach, FL.
K. Marbaugh, B. Li, S. Varanasi, and P. Relue, “Xylulose to furfural: a mathematical modeling assessment of reaction kinetics for dehydration,” 36th Symposium of Biotechnology for Fuels and Chemicals, Poster, April 28-May 1, 2014, Clearwater Beach, FL.
P. Zhang, H. Shao, S. Varanasi, S. Viamajala and P. Relue, “Algae Fermentation to 2,3-Butanediol by Enterobacter cloacae,” 36th Symposium of Biotechnology for Fuels and Chemicals, Poster, April 28-May 1, 2014, Clearwater Beach, FL.
P. Zhang, B. Li, S. Varanasi, and P. Relue, “New route of lignocellulosic biomass sugars fermentation to ethanol by native Saccharomyces cerevisiae” 36th Symposium of Biotechnology for Fuels and Chemicals, Poster, April 28-May 1, 2014, Clearwater Beach, FL.
S. Alipour, S. Viamajala, P. Relue, and S. Varanasi, “Facile Production and In situ Esterification of HMF from Biomass Sugars in Ionic Liquid Media,” AICHE Annual Meeting, paper 726d, November 3-8, 2013, San Francisco, CA.
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B. Li, K. Marbaugh, P. Relue and S. Varanasi, “Xylulose to Furfural, a New Route to Produce High Yield of Furan,” AICHE Annual Meeting, paper 559b, November 3-8, 2013, San Francisco, CA.
H. Shao, S. Varanasi, P. Relue, and S. Viamajala, “Detoxification of Dilute-Acid and Ionic-Liquid Pretreated Wheat Straw Hydrolysates to Improve Succinic Acid Fermentation,” AICHE Annual Meeting, paper 220a, November 3-8, 2013, San Francisco, CA.
K. Marbaugh, B. Li, S. Varanasi and P. Relue, “Mathematical modeling of furfural production from high purity xylulose,” 35th Symposium of Biotechnology for Fuels and Chemicals, Poster 18-23, April 29-May 2, 2013, Portland, OR.
B. Li, P. Zhang, S. Varanasi and P. Relue, “Furfural production from xylulose in a bi-phasic reaction system,” 35th Symposium of Biotechnology for Fuels and Chemicals, Poster 18-24, April 29-May 2, 2013, Portland, OR.
P. Zhang, B. Li, H. Shao, S. Varanasi and P. Relue, “2,3-Butanediol production from xylulose fermentation,” 35th Symposium of Biotechnology for Fuels and Chemicals, Poster 2-14, April 29-May 2, 2013, Portland, OR.
B. Li, P. Zhang, S. Varanasi and P. Relue, “Simultaneous isomerization and reactive extraction of biomass sugars for efficient furan production via high yield ketose intermediate,” 35th Symposium of Biotechnology for Fuels and Chemicals, Poster 3-45, April 29-May 2, 2013, Portland, OR.
W. Porath, M. Ditto, and P. Relue, “Integrating Programmatic Curriculum, Student Development, and Peer Mentoring into an Introductory Course for the Major,” NACADA (National Academic Advising Association) Annual Conference, Nashville, TN, October 4-7, 2012.
B. Li, S. Varanasi, and P. Relue, “High yield ethanol production from fermentation of C5 and C6 biomass sugars by using native yeast,” AICHE Annual Meeting, paper 211b, October 2012, Pittsburgh, PA.
K. Marbaugh, S. Varanasi, and P. Relue, “Separation of sugars from biomass hydrolysates using plasticized liquid membranes,” AICHE Annual Meeting, paper 505c, October 2012, Pittsburgh, PA.
P. Relue, B. Li, and S. Varanasi, “One-pot homogeneous synthesis of furfural from high purity xylulose in aqueous media,” AICHE Annual Meeting, paper 129c, October 2012, Pittsburgh, PA.
H. Shao, B. Li, P. Relue, and S. Varanasi, “Detoxification of ionic-liquid pretreated wheat straw hydrolysate improves succinic acid fermentation performance,” 34th Symposium of Biotechnology for Fuels and Chemicals, Poster 13-28, April 30-May 3, 2012, New Orleans, LA.
K. Marbaugh, S. Varanasi, and P. Relue, “Characterization of plasticized liquid membranes with application for sugar separation,” 34th Symposium of Biotechnology for Fuels and Chemicals, Poster 13-30, April 30-May 3, 2012, New Orleans, LA.
B. Li, P. Relue, and S. Varanasi, “Simultaneous Isomerization and Reactive Extraction (SIRE) of Xylose for High Yield Production of Xylulose,” 34th Symposium of Biotechnology for Fuels and Chemicals, Poster 13-33, April 30-May 3, 2012, New Orleans, LA.
P. Relue, M. Ditto, and W. Porath, “Integrating Programmatic Curriculum, Student Development, and Peer Mentoring into an Introductory Course for the Major,” NACADA (National Academic Advising Association) Region 5 Conference, Akron, OH, April 11-13, 2012.
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B. Li, P. Relue, S. Varanasi, “Reactive extraction of biomass sugars for more efficient downstream conversion to products, AIChE Annual Meeting, Minneapolis, MN, October 2011.
H. Shao, B. Li, P. Relue, S. Viamajala, and S. Varanasi, “Efficient fermentation of biomass sugars to succinic acid,” 33rd Symposium on Biotechnology for Fuels & Chemicals, Seattle, WA, May 2011.
P. Relue, B. Li, D. Yuan, H. Shao, and S. Varanasi. “Evaluation of Oxianions for Shifting the Xylose:Xylulose Equilibrium with Immobilized Xylose Isomerase,” AIChE Annual Meeting, Salt Lake City, UT, November 2010.
P. Relue, B. Li, D. Yuan, H. Shao, and S. Varanasi. “Evaluation of Immobilized Boronic Acid for Shifting the Xylose:Xylulose Equilibrium with Immobilized Xylose Isomerase,” AIChE Annual Meeting, Salt Lake City, UT, November 2010.
D. Yuan, B. Li, H. Shao, S. Varanasi and P. Relue. “Adaptation of Native S. cerevisiae for Improved Xylulose Utilization,” 32nd Symposium on Biotechnology for Fuels and Chemicals, Clearwater Beach, FL, April 2010.
B. Li, D. Yuan, H. Shao, P. Relue and S. Varanasi. “Immobilization of urease for a microenvironmental pH control system: effect of media additives on enzyme activity,” 32nd Symposium on Biotechnology for Fuels and Chemicals, Clearwater Beach, FL, April 2010.
H. Shao, D. Yuan, B. Li, P. Relue and S. Varanasi. “Efficient fermentation of biomass sugars to lactic acid,” 32nd Symposium on Biotechnology for Fuels and Chemicals, Clearwater Beach, FL, April 2010.
B. Li, D. Yuan, P. Relue and S. Varanasi. “Theory for dual-layer co-immoblization of xylose isomerase with urease,” UT Midwest Graduate Research Symposium, Toledo, OH, March 2010.
D. Yuan, B. Li, S. Varanasi and P. Relue. “Efficient Bioconversion of Glucose and Xylose From Popar Hydrolysate to Ethanol,” UT Midwest Graduate Research Symposium, Toledo, OH, March 2010.
D. Yuan, B. Li, S. Varanasi and P. Relue. “A Native S. cerevisiae Fermentation Methodology for Converting Glucose and Xylose From Biomass Hydrolysate to Ethanol,” AIChE Annual Meeting, Nashville, TN, November 2009.
B. Li, D. Yuan, P. Relue and S. Varanasi. “Evaluation of Enzyme Immobilization Methods for Xylose-to-Xylulose Isomerization,” AIChE Annual Meeting, Nashville, TN, November 2009.
D. Yuan, P. Relue, and S. Varanasi, “A Viable Method for Fermenting Both Glucose and Xylose to Ethanol Using Native Yeast,” 31st Symposium on Biotechnology for Fuels & Chemicals, San Francisco, CA, May 2009.
P. Relue and S. Varanasi, “A novel SIF strategy for co-fermentation of C5 and C6 sugars with native yeast,” DOE Office of the Biomass Program, Biochemical Platform Review Meeting, Denver, CO, April 2009.
D. Yuan, P. Relue, and S. Varanasi, “A Simultaneous Isomerization and Fermentation (SIF) Process for Co-fermentation of Glucose and Xylose,” UT Graduate Student Association Research Symposium, Toledo, OH, received 1st place poster award, April 2009.
B. Li, D. Yuan, S. Varanasi, and P. Relue, “Xylose isomerization to xylulose with urease-coated xylose isomerase,” UT Graduate Student Association Research Symposium, Toledo, OH, received honorable mention poster award, April 2009.
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K. Rao, S. Varanasi, P. Relue, “A Novel Approach for Conversion of Xylose to Ethanol Using Native Strains of Yeast,” 30th Symposium on Biotechnology for Fuels & Chemicals, New Orleans, LA, May 2008.
K. Rao, S. Varanasi, and P. Relue, “A Novel Approach for Conversion of Xylose to Ethanol Using Native Yeast Strains,” AIChE 2007 Annual Meeting, Salt Lake City, UT, Nov 5-9, 2007.
K. Rao, S. Chelikani; P. Relue, and. S. Varanasi, “A Novel technique for Optimizing the Simultaneous-Isomerization-and-Fermentation (SIF) Approach of Converting Xylose to Ethanol,” 29th Symposium on Biotechnology for Fuels & Chemicals, Denver, CO, May 2007.
K. Rao, S. Chelikani, R. Fournier, P. Relue and S. Varanasi, “Novel Approach for Conversion of Xylose to Ethanol,” AIChE 2006 Annual Meeting, San Francisco, CA, Nov 12-17, 2006.
Y. Yuan, P.A. Relue, and B.D. Cameron, “Fluorescence Anisotropy Investigation of Metabolic Properties of Human Melanocytes and Melanoma Cells,” BMES Annual Meeting, Chicago, IL Oct 11-14, 2006.
Y. Yuan, Y. Li, R. Criss, P. A. Relue, B.D. Cameron, “Polarized fluorescence spectroscopy of skin for potential tissue diagnostics,” Great Lakes Photonics Symposium, June 7-11, 2004, Case Western Reserve University.
P. Relue and T. Phares, “Bioprocessing Laboratory at the University of Toledo,” PEBEL Conference on Laboratory Partnership, June 4-6, 2004, National Conference Center, Lansdowne, VA.
S.V. Patwardhan, A.P. Dhawan, and P.A. Relue, “Wavelength Selection for Multi-Spectral Imaging of Skin Lesions,” Proc. IEEE 29th Annual Northeast Bioengineering Conference, 2003, p. 327-328.
K.G. Smith and P.A. Relue, “Effects of Cellular Differentiation on Autofluorescence Emission from Tissue Engineered Epidermis,” 2002 BMES/EMBS Annual Fall Meeting, October 23-26, 2002, Houston, TX.
K.G. Smith, P.A. Relue, A.P. Dhawan, “Autofluorescence Characterization of Tissue Engineered Epidermis Towards Early Detection of Melanoma,” 2001 BMES Annual Fall Meeting, October 4-7, 2001, Raleigh-Durham, NC.
A. Kumar, A.P. Dhawan, P.A. Relue, P.K. Chaudhuri, “Restoration of Inhomogeneously Trans-Illuminated Color Images of Skin Lesions,” World Congress on Medical Physics and Biomedical Engineering, July 23-28, 2000, Chicago, IL.
Y. Chen, K. Biddell, A. Sun, P.A. Relue, J.D. Johnson, “An automatic cell counting method for optical images,” EMBS/BMES International Joint Conference, Oct. 13-16, 1999, Atlanta, GA.
A. Kumar, A.P. Dhawan, P. Relue, P.K. Chaudhuri, “Multi-Spectral Optical Imaging of Skin to Diagnose Malignant Melanoma,” EMBS/BMES International Joint Conference, Oct. 13-16, 1999, Atlanta, GA.
P.A. Relue, B. Cheng, and R.L. Fournier, “Study on the inhibition of E. coli lac operon gene expression by triplex-forming oligonucleotides,” 1998 Annual AIChE Meeting, Miami Beach, FL, Nov. 1998.
A. Sun and P.A. Relue, “In Vitro Studies of PDT-Induced Apoptosis,” BMES 1998 Annual Fall Meeting, Cleveland, OH, Oct. 1998.
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P.A. Relue, B. Cheng, R.L. Fournier, S. Varanasi, “Genetically Structured Model for Control of Gene Expression by Antigene Oligonucleotides,” 1997 Annual AIChE Meeting, Los Angeles, CA, Nov. 1997.
B. Cheng, R.L. Fournier, and P.A. Relue, “Model Prediction of the Inhibition of Gene Expression by Antigene Oligonucleotides,” BMES 1997 Annual Fall Meeting, San Diego, CA, Oct. 1997.
J. Yuan, P.A. Mahama, R.L. Fournier, J.A. Hampton, and C.A. Bennett, “Optimization of Singlet Oxygen Generation During PDT Treatment of Tumors,” 1996 Annual AIChE Meeting, Chicago, IL, Nov. 1996.
P.A. Mahama, R.L. Fournier, S. Varanasi, G. Chen, and J.P. Byers, “A Mathematical Model of Urease-Mediated Intracellular pH Control in Helicobacter pylori,” 1996 Annual AIChE Meeting, Chicago, IL, Nov. 1996.
J. Yuan, P.A. Mahama, R.L. Fournier, and J.A. Hampton, “An Investigation of Tumor Oxygenation and Cell Killing During Photodynamic Therapy,” 1995 Annual AIChE Meeting, Miami Beach, FL, Nov. 1995.
J.J. Linderman, P.A. Mahama, and L.D. Shea, “Modeling of Signal Transduction via G-Proteins,” Second International Conference on Cell Engineering, La Jolla, CA, Aug. 1995.
J.J. Linderman and P.A. Mahama, “Simulation of Ligand-Induced Activation of Membrane Proteins,” International Federation of Automatic Control (IFAC) Symposium on Modeling and Control in Biomedical Systems, Galveston, TX, Mar. 1994.
P.A. Mahama and J.J. Linderman, “Monte Carlo Simulations of Ligand-Induced Activation of Membrane Enzymes,” 1993 Annual AIChE Meeting, St. Louis, MO, Nov. 1993.
P.A. Mahama and J.J. Linderman, “Effect of Receptor Agonists/Antagonists on [Ca2+] Mobilization: Digital Fluorescence Imaging and Monte Carlo Modeling,” BMES 1993 Annual Fall Meeting, Memphis, TN, Oct. 1993.
P.A. Mahama and J.J. Linderman “Monte Carlo Simulation of Membrane Signal Transduction Events,” 1992 Annual AIChE Meeting, Miami Beach, FL, Nov. 1992.
P.A. Mahama and J.J. Linderman “Investigation of Calcium Signaling in BC3H1 Muscle Cells Using Digital Fluorescence Imaging,” 1991 Annual AIChE Meeting, Los Angeles, CA, Nov. 1991.
Invited Presentations:
“Tapping into Innovation: Engineering Design, Biobased Products, & BIOE Freshmen Design Experience,” Toledo Early College High School, Science Fair Symposium, May 6, 2016.
“Tapping into Innovation: Biobased Products, NSF I-Corps & BIOE Freshmen Design Club,” Believe in Ohio, presentation to high school students, Nov 20, 2015.
“Biobased Products from Lignocellulosic Biomass: Sugars to Platform Molecules,” FABE Department Seminar Series, Ohio State University Wooster Campus, November 25, 2014.
“Sustainability, energy and options: It’s all a matter of time,” Toledo Early College High School Career Symposium, April 20, 2012.
“Sustainability: A Panel Discussion,” M. Franchetti, G.G. Lipscomb, and P. Relue, UT Theta Tau Engineering Fraternity, March 21, 2011.
“Biomass to Fuel,” UT ACS Chemistry Club, Toledo, OH, April 26, 2010.
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“Forest Biomass to Fuel,” P. Relue and S. Varanasi, Society of American Foresters (Ohio Chapter), Spring Annual Meeting, OSU Campus, Columbus, OH, March 18, 2009.
“Biophotonics: Light at the Interface of Medicine and Engineering,” ASME, University of Toledo, February 13, 2008.
“Optical imaging and Photodynamic Therapy,” SWE, University of Toledo, November 7, 2007.
“Optical Imaging for Detection of Melanoma,” Short course/workshop on Biophotonics: Principles, Practice, and Applications, January 13-16, 2003, Manoa Valley, Hawaii.
“Tissue Engineered Melanoma Phantoms for Optical Imaging,” ACS Central/Great Lakes Regional Meeting, June 26-29, 2002, Ypsilanti, MI.
“Optical Methods of Cancer Treatment and Detection,” Department of Biomedical Engineering, New Jersey Institute of Technology, Newark, NJ, Feb. 2001.
“Tissue Optics and Melanoma Detection,” Department of Chemical Engineering, Virginia Tech, Blacksburg, VA, Dec. 2000.
“Biophotonics: Tumor Treatment and Tissue Characterization,” Department of Health Informatics, University of Medicine and Dentistry of New Jersey, Newark, NJ, July 2000.
“Can Engineers Improve Cancer Therapy?” Ford Motor Company, Scientific Research Laboratory, Dearborn, MI, July 1998.
“Mathematical Modeling of Photodynamic Therapy,” Molecular and Cellular Biology Seminar Series, The Medical College of Ohio, Toledo, OH, Feb. 1998.
“Photodynamic Therapy: Mathematical Modeling and Experimental Studies,” Department of Bioengineering Seminar Series, The University of Toledo, Toledo, OH, Jan. 1998.
“Mathematical Modeling of Tissue Oxygenation and Photodynamic Therapy,” Sequus Pharmaceuticals, Menlo Park, CA, Jan. 1998.
“Photodynamic Therapy: Mathematical Modeling and Experimental Studies,” Pharmacy Seminar Series, The University of Toledo, Toledo, OH, Oct. 1997.
“Digital Fluorescence Imaging and Applications,” Bioengineering Seminar Series, The University of Toledo, Toledo, OH, Mar. 1996.
“Calcium Signaling in Single Cells: Mathematical Modeling and Digital Fluorescence Imaging,” Biology Colloquium, The University of Toledo, Toledo, OH, Dec. 1994.
“Calcium Signaling in Single Cells,” Biological Sciences Seminar, Bowling Green State University, Bowling Green, OH, Apr. 1994.
“Signal Transduction in Single Cells: Digital Fluorescence Imaging and Mathematical Modeling,” Pharmacy Seminar Series, The University of Toledo, Toledo, OH, Feb. 1994.
Grants and contracts: funded
“High yield production of furans from biomass hydrolysates using a hybrid enzyme- and chemo-catalytic technology,” S. Varanasi and P. Relue, NSF PFI AIR-TT - GRAD Supplement, $10,000, May 2016 – April 2017.
“High yield production of furans from biomass hydrolysates using a hybrid enzyme- and chemo-catalytic technology,” S. Varanasi and P. Relue, NSF PFI AIR-TT - REU Supplement, $12,000, May 2016 – April 2017.
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“High yield production of furans from biomass hydrolysates using a hybrid enzyme- and chemo-catalytic technology,” S. Varanasi and P. Relue, NSF PFI AIR-TT - RET Supplement, $10,000, May 2016 – April 2017.
“High yield production of furans from biomass hydrolysates using a hybrid enzyme- and chemo-catalytic technology,” S. Varanasi and P. Relue, NSF Partnerships for Innovation Program: Accelerating Innovation Research - Technology Translation (PFI AIR-TT), $200,000, April 2015 – Oct 2017.
“Simultaneous Isomerization and Reactive Extraction of Biomass Sugars for High Yield Production of Ketose Sugars,” S. Varanasi and P. Relue, NSF CBET - GRAD Supplement, $10,000, May 2016 – April 2017.
“Simultaneous Isomerization and Reactive Extraction of Biomass Sugars for High Yield Production of Ketose Sugars,” S. Varanasi and P. Relue, NSF CBET - REU Supplement, $15,000, May 2016 – April 2017.
“Structured recitation for Freshman Design Experience in BIOE 1000,” P. Relue, UT Innovations in Teaching Award, $3,500, Summer 2015.
“Simultaneous Isomerization and Reactive Extraction of Biomass Sugars for High Yield Production of Ketose Sugars,” S. Varanasi and P. Relue, NSF CBET - REU Supplement, $15,000, Aug 2014 – July 2016.
“Simultaneous Isomerization and Reactive Extraction of Biomass Sugars for High Yield Production of Ketose Sugars,” S. Varanasi and P. Relue, National Science Foundation – CBET Division, $309,524, Aug 2012 – July 2017.
“Center for Algal Engineering Research and Commercialization,” S. Viamajala, S. Varanasi, C. Schall, and P. Relue, Ohio Third Frontier Wright Project Program, $2,970,063 (Ohio University lead, with $1,027,061 UT subcontract), July 2010 – July 2013.
“Development of co-immobilized enzyme pellets to replace GMOs for cellulosic ethanol,” G. Kumar, D. Sen (SuGanit), S. Varanasi, and P. Relue (UT), USDA-CREES SBIR Phase I, $80,000 (UT subcontract $20,000), Jan 2010 – May 2010.
“Scale up of Cellulosic Ethanol Process Based on Novel Biomass Pretreatment and Efficient Co-Fermentation,” SuGanit Systems, Inc and University of Toledo (S. Varanasi, C. Schall, P. Relue, and J. Anderson), 2009 Third Frontier Advanced Energy Program, $999,900, (UT subcontract $505,000), April 2009 – Dec 2011.
“A novel simultaneous-saccharification-fermentation strategy for efficient co-fermentation of C5 and C6 sugars using native, non-GMO yeasts,” S. Varanasi and P. Relue, Department of Energy (DOE) Office of Biomass Program, $499,784, Sept 2008 – June 2013.
“A Novel Cellulosic Biomass Fermentation Process for Ethanol Production,” S. Varanasi, P. Relue (UT), P. Parapati, and G. Kumar (SuGanit), 2008 Third Frontier Advanced Energy Program, $250,000, June 2008 – Aug 2009.
“Co-immobilized enzyme pellets for C5 and C6 sugar fermentation to ethanol,” P. Relue, 2008 UT URAF Summer Fellowship, $12,000, April 2008 – June 2009.
“Redevelopment of BIOE 1000 Introduction to Bioengineering,” P.A. Relue, Center for Teaching and Learning, $10,000, The University of Toledo, May – Dec, 2007.
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“Cost-competitive approach for ethanol production from lignocellulose biomass based on recombinant DNA technology,” P. Relue, UT Summer Research Fellowships and Research Grants Program, $5,500, May –Dec. 2005.
“Northern Ohio Center of Excellence in Product Development,” State of Ohio Third Frontier Product Development Pilot Program, Apr 2005 – Mar 2007, $1,231,600 (UT subcontract $140,000), Principal Investigator: S. Gage, CAMP, Inc.; UT - B. Cameron (PI), S. Molitor (co-I) and P. Relue (co-I).
“Polarization Sensitive Autofluorescence Imaging for Potential Skin Cancer Diagnostics,” B. Cameron (P.I.) and P. Relue (co-PI), Skin Cancer Foundation, $10,000, Apr 2003 – Mar 2004.
“Acoustic Emission Based Stress Fracture Surveillance System for Prediction of Stress Fractures,” O. Akkus (PI), P.A. Relue (co-I), V.K. Goel (co-I), and M.S. Hefzy (co-I), Department of Defense, U.S. Army Medical Research and Material Command, $199,179, Sept 2003 – Aug 2006.
“Enhancing Engineering Education in Biophotonics,” P.A. Relue, UT Center for Teaching and Learning, $300, used to cover partial tuition for shortcourse in Biophotonics, Jan 2003.
“Autofluorescence Imaging for the Characterization and Detection of Skin Lesions,” P. Relue (PI), A. Dhawan, and P. Chaudhuri, The Whitaker Foundation, $209,805, Jan 2000 – Dec 2002.
“Industrial Internship Program for Biomedical Engineering Students,” R. Fournier (Project Director), P. Relue, H. Kohler, The Whitaker Foundation, $180,000, May 1999- April 2002.
“Flow Cytometry System for Cellular Engineering Research,” P. Relue (PI), S. Sharfstein, and R. Fournier, National Science Foundation, $67,200, ($134,400, 50% UT cost share) June 1998 – May 2000.
“A Focus on Cellular and Physiologically-Based Medical Imaging,” R Fournier (Project Director), Team Members (HG Beebe, PK Chaudhuri, AP Dhawan, J Jankun, RW Komuniecki, J Lu, WS Messer, Jr., P. Relue, SX De Salles-Cunha, SH Selman), The Whitaker Foundation, $841,579, Nov 1998 – Aug 2002.
“Singlet oxygen exposure and apoptosis in tumor cells,” P. Relue, deArce Memorial Endowment Fund, $10,406, Dec. 1997 – Dec. 1998.
“Biotechnology and Bioprocessing Laboratory,” S. Sharfstein and P. Mahama, National Science Foundation Instrumentation and Laboratory Improvements Program, $28,849, ($57,698, 50% UT cost share) July 1997 – July 2000.
“Intracellular Engineering of Triplex Oligonucleotides for the Treatment of Bacterial Infections,” R. Fournier, P. Mahama, and S. Varanasi, UT Research Challenge Program, $37,905, Apr. 1996 – Dec. 1996.
“Fluorescence Imaging of Ligand-induced Calcium Imaging in Single Cells,” P. Mahama, UT Summer Research Fellowships and Research Grants Program, $7,412, June 1996 – Dec. 1996.
“Measuring the Kinetics of Cell Killing and the Mode of Cell Death Induced by Direct Cell Kill in Photodynamic Therapy,” deArce Memorial Endowment Fund, P. Mahama, $10,000, Mar. 1995 – Dec. 1995.
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Equipment donations:
“Fermentation controller module for undergraduate bioprocessing,” P. Relue, Eppendorf, Inc., Enfield, CT, Equipment value of ~$20,000 if purchased from the manufacturer, 2016.
“Enhancement of bioprocessing laboratory for bioengineering undergraduates,” P. Relue, Pfizer Drug Discovery Technologies Group, Ann Arbor MI, Equipment value of ~$250,000 if purchased from manufacturer, 2004.
“Using Electrolytic Respirometry to Determine Bacterial Respiration Rates and Biodegradability,” P. Relue, $60,000 equipment donation (electrolytic respirometer and computer acquisition system), Ford Motor Company, Mar. 1998.
VII. SERVICE
Professional Society Membership:
Date Organization/Society
2009 – 2015 Society for Industrial Microbiology (SIM)
2012 – 2013 National Academic Advising Association (NACADA)
1997 – 2004; 2014 – present
Biomedical Engineering Society (BMES)
1996 – 2004 American Association for the Advancement of Science (AAAS)
1988 – present American Institute of Chemical Engineers (AIChE)
1994 – 1996 American Society for Engineering Education (ASEE)
Honors and Awards:
Year Award/Recognition
2015 Alice H. Skeens Outstanding Woman Award, University Women’s Commission, The University of Toledo
2009-10; 2005-06; 1996-97
Outstanding Professor in Bioengineering, Biomedical Engineering Society student chapter, The University of Toledo
2007 Outstanding Teacher Award, College of Engineering, The University of Toledo
1998 Dean’s Merit Award, College of Engineering, The University of Toledo
1997 – present Sigma Xi, The University of Toledo
1997 Outstanding Teacher Award, The University of Toledo
Other Professional Service and Experience: Chaired Conference Sessions:
Date Conference and location Session Co-chair
April 2014 Symposium on Biotechnology for Fuels and Chemicals (Society for Industrial Microbiology)
Bioprocessing, Reactor Design, and Separations Technology I
Nov 1999 AIChE National Meeting, Dallas, TX Tissue Engineering
Nov 1998 AIChE National Meeting, Miami Beach, FL Cell Adhesion and Migration
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Nov 1997 AIChE National Meeting, Los Angeles, CA Emerging Issues in
Bioengineering Education
Nov 1996 AIChE National Meeting, Chicago, IL Receptor-Mediated Cell Phenomena
Other Professional Service and Experience: Conference Attendance and Continuing Education:
Date Conference/Course
Mar 2-6, 2016 VentureWell OPEN Conference, Portland, OR
July 22-23, 2015 Midwest Engineering & Entrepreneurship Network, Purdue University, Lafayette, IN
Apr 28-May 1, 2014
36th Symposium of Biotechnology for Fuels and Chemicals, Clearwater Beach, FL
Apr 29 – May 2, 2013
35th Symposium on Biotechnology for Fuels & Chemicals, Portland, OR
Oct 2012 AIChE National Meeting, Pittsburgh, PA
Apr 30 – May 3, 2012
34th Symposium on Biotechnology for Fuels & Chemicals, New Orleans, LA
May 2-6, 2011 33rd Symposium on Biotechnology for Fuels & Chemicals, Seattle, WA
Nov 2010 AIChE National Meeting, Salt Lake City, UT
Apr 18-22, 2010 32nd Symposium on Biotechnology for Fuels & Chemicals, Tampa, FL
Nov 2009 AIChE National Meeting, Nashville, TN
May 10-13, 2009 31st Symposium on Biotechnology for Fuels & Chemicals, San Francisco, CA
June 4-6, 2004 PEBEL Conference on Laboratory Partnership, National Conference Center, Lansdowne, VA
Jan 13-16, 2003 Short course: Biophotonics: Principles, Practice, and Applications, Manoa Valley, HI
Oct 2002 BMES Annual Fall Meeting, Houston, TX
Aug 2002 Whitaker Foundation Biomedical Engineering Research Grants Conference, San Diego, CA
June 26-29, 2002 ACS Central/Great Lakes Regional Meeting, Ypsilanti, MI
Jan 2002 SPIE Photonics West Conference, San Jose, CA
Nov 2001 AIChE National Meeting, Reno, NV
Oct 2001 BMES Annual Fall Meeting, Raleigh-Durham, NC
Aug 2001 Whitaker Foundation Biomedical Engineering Research Grants Conference, San Diego, CA
June 2001 NIH BECON Tissue Engineering Symposium, Washington D.C.
July 23-28, 2000 World Congress on Medical Physics and Biomedical Engineering, Chicago, IL
Nov 1999 AIChE National Meeting, Dallas, TX
May 1999 Flow cytometry training course, Becton-Dickinson, San Jose, CA
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Nov 1998 AIChE National Meeting, Miami Beach, FL
Oct 1998 BMES Annual Fall Meeting, Cleveland, OH
Nov. 1997 AIChE National Meeting, Los Angeles, CA
Oct 1997 BMES Annual Fall Meeting, San Diego, CA
July 14-19,1997 Shortcourse: Laboratory in Molecular and Cellular Science, Center for Engineering in Medicine, Massachusetts General Hospital, Boston, MA
Nov 1996 AIChE National Meeting, Chicago, IL
Nov 1995 AIChE National Meeting, Miami Beach, FL
Aug 1-5, 1995 Shortcourse: Tissue Engineering, Institute of Biosciences and Bioengineering, Rice University, Houston, TX
Nov 1993 AIChE National Meeting, St. Louis, MO
Oct 1993 BMES Annual Meeting, Memphis, TN
Nov 1992 AIChE National Meeting, Miami Beach, FL
Nov 1991 AIChE National Meeting, Los Angeles, CA
Nov 1990 AIChE National Meeting, Chicago, IL
Other Professional Service and Experience: Professional service:
Date Activity
Apr 1996 – Apr 1998
Computational Biology Review Panel, National Science Foundation, Arlington, VA
Jan –Sept. 1996 GRE Mathematical Reasoning - Pilot Test Development, Education Testing Service, Princeton, NJ
Jan – Dec 1995 Question Writer/Reviewer, GRE Subject Test in Engineering, Education Testing Service, Princeton, NJ
June 1995 – Jan 1996
Isaac Corporation, Consultant, Defiance, OH
Aug 1994 Ford Motor Company, Instructor, Creative Problem Solving, Avon Lake, OH
Other Professional Service and Experience: Manuscript reviewer:
Green Chemistry
Photochemistry and Photobiology
Biophysical Journal
The Journal of Theoretical Biology
IEEE Transactions on Biomedical Engineering
Other Professional Service and Experience: University, College, and Department:
UT/UM NSF I-Corps – Program coordinator; Faculty, Mentor and Teaching Team recruiter – Fall 2014/Spring 2015
UT Graduate Council, May 2005 – May 2014; Spring 2017
Chair, May 2008 – May 2009;
Curriculum Committee, May 2006 – May 2008; Aug 2010 - present;
Chair May 2006 – May 2008, Aug 2010 – May 2012, Oct. 2015 - present
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Executive Committee, May 2008 – May 2013;
Ad hoc committee to develop dissertation tracking system (GDOCS), Jan 2011 – Dec 2011.
UT Faculty Senate, 2007-2008; 2012 – present;
Academic Affairs Committee 2007-08; 2013-2015;
Academic Programs Committee, 2013 – present;
Committee on Committees 2009, 2013; 2014
Faculty Affairs Committee, 2012-13;
Student Affairs Committee, 2012-13.
UT Research Council, 2013- present.
University Committee on Sabbaticals, 2010 to present; Chair 2011-12; 2013-14; 2014-15, 2015-16
UT Outstanding Teacher Award selection committee, 2009, 2010, and 2011.
UT College of Engineering Dean search committee, 2017
UT College of Graduate Studies Dean search committee, 2008.
Undergraduate Summer Fellowship and Creative Activity Program, proposal reviewer, 2006
UT Radiation Safety Committee, 1998 – 2003; chair, 1998 – 2001
UT Sigma Xi; Outstanding Researcher Award Committee, 2001
UT Visual Arts Committee, 1998 – 1999
Biomedical Engineering PhD Program Administrative Committee, 2007 – present; Qualifying Examination (QE) Committee 2007-present
QE Chair, 2008, 2012, 2013, 2014, 2015, 2016
College of Engineering Diversity Committee, 2016 – present
College of Engineering Library Committee, 2003 – 2008
College of Engineering Dean’s Advisory Council, 2000 – 2003
Phi Sigma Rho Faculty Advisor, 1999 – present
SWE Faculty Advisor, 1999 - 2001
BIOE Department Personnel Committee, 1999 – present; Chair 2006-07; 2014-present.
BMES Faculty Advisor, 1999 – 2001; 2014 – present