Current Research aug07 - Texas Department of State Health ... · Cherie Simpson, RN CNS Senior...
Transcript of Current Research aug07 - Texas Department of State Health ... · Cherie Simpson, RN CNS Senior...
AlzheimerAlzheimer’’s Diseases Disease--Update on Current Update on Current
ResearchResearchCherie Simpson, RN CNSCherie Simpson, RN CNS
Senior Adult Specialty Healthcare Senior Adult Specialty Healthcare and Researchand Research
New Twist on Current MedicinesNew Twist on Current Medicines
RivastigmineRivastigmine TransdermalTransdermal PatchPatchComparison of 23mg Comparison of 23mg DonepezilDonepezil SR to 10 mg IMSR to 10 mg IMMemantineMemantine
Delaying the progression of driving impairmentDelaying the progression of driving impairmentIn combination with Vitamin EIn combination with Vitamin ECompared to Compared to DonepezilDonepezil in early stagesin early stagesCommunicationCommunicationComprehensive, Individualized Management of AD Comprehensive, Individualized Management of AD and Caregiver Burdenand Caregiver Burden
New Twists New Twists
EstrogenEstrogen
TestosteroneTestosterone
LevadopaLevadopa
DHADHAIsoflavonesIsoflavonesAntioxidantsAntioxidants
Not Just Nutritional SupplementsNot Just Nutritional Supplements
Two In OneTwo In One
ZTZT--11
PRXPRX--03140314
LifeStyleLifeStyle
EXERCISE
Insulin/Glucose ConnectionInsulin/Glucose Connection
RosiglitazoneRosiglitazoneDD--pinitolpinitolSNIFF 120SNIFF 120
Altering or Preventing the DiseaseAltering or Preventing the Disease
VaccineVaccineWyeth/ElanWyeth/Elan (II, III soon)(II, III soon)Novartis/CytosNovartis/Cytos (I)(I)Merck (I)Merck (I)AffirisAffiris (I)(I)Institute of Molecular Institute of Molecular MedicineMedicine
Altering or Preventing the DiseaseAltering or Preventing the Disease
Selective AmyloidSelective Amyloid--beta lowering agents beta lowering agents ALAL--108108AntibioticsAntibioticsNonsteroidalNonsteroidalSimvastatinSimvastatinVitamin E and SeleniumVitamin E and Selenium
Future ResearchFuture Research--ItIt’’s On Goings On Going
SKSK--PCPC--B70M (II)B70M (II)HF0220 (II)HF0220 (II)GSK933776A (I)GSK933776A (I)PFPF--04360365 (I)04360365 (I)PAZPAZ--417, SAM315 (I)417, SAM315 (I)CTSCTS--2166 (going to II)2166 (going to II)
Treating the Behavioral and Treating the Behavioral and Psychological SymptomsPsychological Symptoms
DepressionDepression
ApathyApathy
AgitationAgitation
Disrupted sleepDisrupted sleep
Problems with Problems with Activities of Daily Activities of Daily LivingLiving
DepressionDepressionSertralineSertralineEscitalopramEscitalopramAntidepressant + Antidepressant + DonepezilDonepezil
ApathyApathyMethylphenidateMethylphenidate
Treating the Behavioral and Treating the Behavioral and Psychological SymptomsPsychological Symptoms
Treating the Behavioral and Treating the Behavioral and Psychological SymptomsPsychological Symptoms
AgitationAgitationMemantineMemantineAnitpsychotic/divalproexAnitpsychotic/divalproexDiscontinuation of antipsychoticDiscontinuation of antipsychoticPrazosinPrazosinBifeprunoxBifeprunox
Treating the Behavioral and Treating the Behavioral and Psychological SymptomsPsychological Symptoms
SleepSleep
BathingBathing
Other ResearchOther Research
REVEAL IIIREVEAL IIICouples CopingCouples CopingIntervention for AdultIntervention for Adult--Child CaregiversChild Caregivers
ResourcesResources
www.clinicaltrials.govwww.clinicaltrials.govSearch by Search by ““AlzheimerAlzheimer’’s Diseases Disease”” or by drug or by drug companycompany
www.alz.orgwww.alz.orgResearchResearch
www.alzforum.orgwww.alzforum.orgAlzheimerAlzheimer’’s Research Forums Research Forum