CTMA / DLD-Bio « Academic - Military - Industrial » Interface · protection DG SANCO Health...
Transcript of CTMA / DLD-Bio « Academic - Military - Industrial » Interface · protection DG SANCO Health...
CTMA / DLD-Bio
« Academic - Military - Industrial » Interface
EU
Commission
Bio threats
Biomedical
EU Defense
Agency NATO
networks
UCL and CUSL
Academic hospital
CTMA DLD-Bio
EU Space
Agency
Military partners
Integrated Mission Group in Security (IMG-S)
Academic partners In
tera
tion
al
Nati
on
al
Industrial partnership
and valorisation
(SME’s, industries)
Regional / federal
R&D projects
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Civ-Mil cooperation : vision / mission B
io –
Na
no
– IC
T
Iso
latio
n
C
on
ve
rge
nce
CTMA multidisciplinary - multinational R&D Programme
Set-Up multidisciplinary convergence, national and international partnerships
Scientific Expertise
Invention, Patent
Valorisation, Spin-off
Economic value
Civ-Mil transfert of dual Technologies:
CTMA « R&D CBRN-Matrix »
Civ-Mil Joint contribution
BioEDEP,
JIP-CBRN,
CBRN Cat B
COST, PASR,
FP7
Horizon 2020
IAP/ARTES20
Phase-1
Phase-2
EDA
Marshall plan
Biowin, Waleo,
WBHealth
FEDER
Erasmus Mundi
Regional / Federal
R&D projects
BE-MOD
RHID-projects
Interuniv. Attraction
Pole (PIC)
Brain-Belspo
EC
ESA
NATO
IMG-S (CBRN Think tank)
MED
LAND
DLD
BE-Biotech
(SME’s, Industries)
The matrix allows to spread costs, to mutualize the benefits and to decrease the failure rate
CBRN-SIBCRA
Science for Peace & Sec
(SPS)
• CBRN Threats: same issues, shared concerns and some
similiraties in preparedness at the Civ and Mil level
• Observations
– 1: Major biothreat crisis : from « mil » to « civ-mil » cooperation !
– 2: Dual use testing in specialised « reach back » infrastructure
– 3: From «reach back testing » to «on-site testing» !
– 4: Deployability & in-field testing: new constraints and R&D activities !
– 5: How to integrate «space-technologies» and « which ones» ? ,
• Way ahead: Civ-Mil R&D // Ops-tools integrator // Multiuse
Civ-Mil cooperation: the rationale ?
années heures Hours Days Years
Dea
ths
C / E
B C / E
B
Biological agents : Mostly covert incidents with delayed lethality
Impact = (% affected) X (speed of spread)
Risk = Likelihood X Impact
EU Bodies
Industry, Stakeholders, NGO’s, Researchers, Experts, etc.
Member States
(Committees)
CBRN Policy implementation:
a coordinated approach
EU Policies EU Research
DG RTD
Research
DG CNECT
Comm.
JRC
Joint Res.
Centre
DG ENTR
Security DG TAXUD
Border
surveillance
DG MOVE
Transport
DG TRADE
Trade
ECHO
Civil
protection
DG SANCO
Health
Security
Agencies
DG HOME
CBRNE Action
Plan
DG DEVCO
CBRN Centres
Of excellence
EEAS
Ext. security
FPI
Foreign Policy
Instr.
EDA
Defense
(EFC)
DG ENV
Environment
(Seveso)
+ UN Bodies, NATO
DG ENER
Energy
CBRN CoE : Eight Regions
Ukraine /Caucasus (2011)
South East Asia (2010)
Middle East (2011)
Africa -1(2011)
Africa-2 (2011)
Planned
Mediterrean Basin
Central Asia
Protect Recover
Respond Prevent
Deter
Ac
tio
ns
to
un
de
rta
ke
ag
ain
st
cau
ses
Ac
tio
ns t
o u
nd
ert
ak
e
ag
ain
st
eff
ects
Before incident During After incident
CBRN Defence System
PREPAREDNESS /
PLANNING RESPONSE / RECOVERY
DETECTION- MONITORING
- IDENTIFICATION
SITUATIONAL AWARENESS & RESILIENCE
CBRN Life Cycle
CB
RN
In
cid
en
t -
Co
nseq
uen
ces
- C
risis
Man
ag
em
en
t
De
cis
ion
Su
pp
ort
- C
om
mu
nic
ati
on
• CBRN Threats: same issues, shared concerns and some
similiraties in preparedness at the Civ and Mil level
• Observations
– 1: Major biothreat crisis : from « mil » to « civ-mil » cooperation !
– 2: Dual use testing in specialised « reach back » infrastructure
– 3: From «reach back testing » to «on-site testing» !
– 4: Deployability & in-field testing: new constraints and R&D activities !
– 5: How to integrate «space-technologies» and « which ones» ? ,
• Way ahead: Civ-Mil R&D // Ops-tools integrator // Multiuse
Civ-Mil cooperation: the rationale !
Observation 1
B-threats are a shared « Civ - Mil concern»
Shift from « Mil-WMD» to « Civ-Mil»- R&D prompted by
- Globalization (missions, intercontinental trips…)
- Rapidly emerging diseases
- Risks arise from remote, poorly accessible areas with weak
health care support
Civ-Mil cooperation: the rationale !
Anthrax : from disease-endemic area to bioterrorism
Accidental (benign) human infection
Deliberate release Civ human infection !
Outside «military field» !
Deadly anthrax cases
Countless anthrax copycats
« Weapanized deadly anthrax»
…BUT
White powder – Anthrax BELGACOM towers, Belgium, 11 Jan 2013
From weapons to major natural outbreaks: From Variola to EBOLA and Monkeypox
Smallpox
Viral Hemorraghic
Fever
Biological weapons
Viral Hemorraghic Fevers in Africa : 2012 3 different outbreaks ! Copyright 2012 - CTMA/DLD-Bio
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Death rate : 50- 70%
Monkeypox, Chickenpox… or Smallpox ?
Some are very contagious and lethal
Need for rapid differential (Mpx) diagnostic tests !
Common Mil-Civ Needs:
Joint efforts and cooperation
VIRUSES FUNGI PROTOZOAE BACTERIA PRIONS (?)
Challenges: Rapid, specific and sensitive DIM
- Deadly for human beings, animals and crops
- Contaminating the environment
TOXINS
Mitigate CBRN risks : Identification tools and technologies
Alike / Dual !
Intentional release only
CBRN cases
Natural outbreak –
Endemic zone
Daily infections
Hospital – Ops «in-field»
POTENTIAL THREATS OCCASIONAL THREATS COMMON THREATS
Best validation & trg model
NOT EXPECTED in environment
Civ-Mil Concern only if
Terrorism - Risk in war zone (Ops)
PRESENT in natural environment
Civ-Mil Concern
Risk in Epid & endemic area in Ops
COMMON in daily life
Civ-Mil Risk anytime, anywhere
Observation 2
Need for rapid, sensitive, reliable detection and
identification of B-agents
Heavy infrastructure (reach back laboratory)
Civ-Mil cooperation: the rationale !
Observation 3
CBRN threats require « rapid on-site testing»:
The concept «Light Fieldable Laboratory or LiFi »
Size ? Specificity ? Sensitivity ? Type of Samples?
Tools (analytical, communication, GIS/EO, Sat
Navigation [GPS/GNSS], robots) ?
Example of Civ-Mil interface
Light Field Bio-Laboratory for Emergencies
Interoperable platform
for CRBN or Health crisis
Identical HEART
CIVILIAN specifications MILITARY specifications
Common Civ-Mil specifications
– Analytical equipement
– Communication, site selection,
georeferencing
– Expertise (human resources)
– Full CBRN shelter protection
– Heavy shelter, slowly deployable
– Sampling team
– Ops military C2
– B-specific
– Light Fieldable
– First responders (nurses, MD)
– GOARN / WHO / EC DEVCO
Scarce « Ops-certified » structure – funding? Several « Ops-certified » structure – joint
capacity is possible – funding possible !!!
Observation 4 « Increased deployability »and « on-site testing :
New constraints = New R&D field for
« Civ-Mil » CBRN activities»
e.g.,Emerging technologies for rapid identification (Protein, DNA,
RNA, multiplexing, isothermal amplification…);
Biosafety (inactivation of pathogens), reagents lyophilization
Example of Civ-Mil cooperation
Light Field Bio-Laboratory for Emergencies
Lifi for
Civ-Mil cooperation in Africa ?
240 Km
Monkeypox MWEKA
Outbreaks 2007 & 2008
RESISTANT TUBERCULOSIS
MALARIA
DREPANOCYTOSIS...etc...
EBOLA
Endemic Monkeypox
area
Deployment in Ops
conditions
No dedicated aircraft !
C130 normal rotation: 3days
Copyright 2012 - CTMA/DLD-Bio
Light Fieldable Detection Laboratory
Kananga, RDC, April 2009
Modular structure : scalability – joint intervention
Successful monitoring of health-threatening
agents nearby a Military settlement
• Monkeypox outbreak - Submitted for publication;
- Oral presentation, Biodefense conference
congress, München, 22 Oct 2013
• Ebola outbreak
Real-time PCR
• Resistant Tuberculosis
Endpoint-PCR
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Observation 5
Light fieldable laboratory:
Communication is crucial !
Needs for integrating CBRN and space tech:
How ? Which ones?
Example of Civ-Mil cooperation
Light Field Bio-Laboratory for Emergencies
29 Integration of Space-based technologies/ tools :
Sat Communications, Sat Navigation (GPS/GNSS), Earth observation (site selection)
Communication between the mobile lab team
the reach back facility and the Ops center ?
– Inter-secure network communication
– Access to distant database
– Information and image transmission
– ….
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B-LiFE
Biological Light Fieldable Laboratory for Emergencies
Proof of Concept 29 Nov 2012
(Anthrax spread in EC premises in Brussels)
Sampling team with smartphones and dedicated applications
Permanent Location
Sampling Process
Alerts Process
Real-Time and smart communication with all necessary parties
Direct connection to central server
Uses all functionalities of last generation phones
Cie CBRN
Bn ….
Copyright 2012- CTMA / DLD-Bio
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Georeferencing Samples
& Sampling team
Earth Observation: (a) Site selection Candidate deployment sites 50-500m (b) Sampling team guidance Sat- and phone-guidance
Soccer field RMS
Copyright 2012 - CTMA/DLD-Bio
• CBRN Threats at a glance
• Observations
– 1: Major biothreat crisis : from « mil » to « civ-mil » cooperation» !
– 2: Dual use testing in specialised « reach back » infrastucture
– 3: From «reach back testing » to «on-site testing» !
– 4: Deployability & in-field testing: new constraints and R&D activities !
– 5: How to integrate «space-technologies» and « which one » ? ,
• Way ahead: Civ-Mil R&D // Ops-tools integrator // Multiuse
Civ-Mil cooperation: way ahead !
Integration of other new technologies
• Energy production and consumption
• Type of shelter
• Improved preanalytical steps (sampling,
processing)
• Link between sampling and processing – robots ?
• Reagents (lyophilisation - Ops)
• Biosafety (glovebox, inactivation)
• Communication (secure data transsmission)
• Logistics, Waste…..
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Deployable laboratory
connected to EU
projects: CBRN matrix
1. FP7-SEC-PRACTICE (2011):
Preparedness and Resilience
against CBRN Terrorism using
Integrated Concepts and
Equipment
2. FP7- SEC-MIRACLE (2013):
MobIle Laboratory for the Rapid
Assessment of CBRN Threats
Located within and outside the EU
(CTMA Coordination )
3. FP7-SEC-EDEN (2013): End-user
driven DEmo for CBRNE
4. FP7-SEC-CAERUS (2014):
Evidence-based policy for post-
crisis stabilisation:bridging the gap
BioEDEP: 2d generation
deployable tactical field
analysis system (project
n°6, phase 1)
EFC
B-LiFE - IAP/ARTES20:
Biological Light Fieldable
laboratory for
Emergencies (CTMA
Coordination)
ESA
EDA
EC-FP7-SEC (CBRN)
CBRN
matrix
CBRN Mil R&D:
Take home message ?
•Mil CBRN Defence capacities are needed … but it
will be difficult to progress as «stand alone» !
•Need for enhanced Civ-Mil joint cooperation –EFC is the “first” craddle….. Not the end !
–ESA and NATO should be part of it !
Due to financial pressure and societal evolution,
survival of “CBRN Mil R&D” implies to meet “wider
societal needs and better EU integration” 38