CT Guided Ozonotherapy with Foraminal Approach for Cervical Herniated Discs:6 Months Follow- Up of...
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Transcript of CT Guided Ozonotherapy with Foraminal Approach for Cervical Herniated Discs:6 Months Follow- Up of...
CT Guided Ozonotherapy with Foraminal Approachfor Cervical Herniated Discs:6 Months Follow- Up
of 50 Patients
Vyletelka J., Labaj V.: Department of Neurology, Žilina,Slovakia
FIO 2007,Bologna, 12.-13.oct.2007
Kongres Talianskej Spoločnosti pre Ozonoterapiu
Patients and methods
- jan 2006 – mar 2007
- 50 patients 27 men
23 women
-age 29 – 69 years, mean age 47,7 years
- all patients provided informed consent
Patients and methods /cont./
Inclusion criteria:
Clinical: -cervical pain resistant for conservative management /drugs,
physiotherapy,bed rest/
-lasting at least 6 weeks
-neurological signs of nerve root involvement
Neuroradiologic: CT and/or MR evidence of cervical disc herniation
/corresponding with patient´s clinical symptoms/
with or without disc degeneration
Patients and methods /cont./
Exclusion criteria:
Patients- with major neurologic deficit
- with EMG features of neurogenic injury and /or denervation
- free fragments of herniated disc
Patients and methods /cont./
Method of aplication: foraminal under CT guidance
Procedure:
Desinfection of injection site
Local anesthesia using an ethyl chloride spray
22-gauge needle / Terumo /, 9 cm
Mixture O2-O3 konc.27ug/ml, volume 2 ml to neural foramen
2 ml to facet joint region
Equipment- ozone generator Alnitec,Cremosano,Italy – allowing the pho-
tometric detection of the concentration of O3 in the gas mix-
ture,constant pressure during the O3-intake operation
CT guided foraminal approach
Patients and methods /cont./
Follow-up:
-after 2 weeks, 3 - 6 months
-outcomes of treatment were classified using :
McGill Pain Questionnaire
modified McNab method
Outcomes evaluations
Visual Analog Scale / VAS /
Outcomes evaluations
Modified version of McNab method:
1.excellent – complete resolution of pain and return to activity before
2.good/satisfactory – reduction of pain by 50% and more
3.mediocre/poor – partial reduction of pain by 30% or less
4.worsening
Results
Disc treated
1. C 3/4 1 patients
2. C 4/5 1 patients
3. C 5/6 25 patients
4. C 6/7 25 patients
0
5
10
15
20
25
C3/4 C4/5 C5/6 C6/7
Treated discs
Results
Number of procedures:
-1x procedure 39 patients
-2x procedure 10 patients
-3x procedure 1 patients
0
5
10
15
20
25
30
35
40
1x 2x 3x
Number of aplications
Results
Modified version of McNab method:
1.excellent 23 / 46 % / patients2.good/satisfactory 18 / 36 % / patients3.mediocre/poor 7 / 14 % / patients4.worsening 2 / 4 % / patients
Surgery 5 / 10 % / patients 3 pt no improvement 2 pt improved
3. months excellent – good/satisfactory 85,00% 6. months 82,00%
82%
Results
McGill Pain Questionnaire – Visual Analog Scale / VAS /
-before treatment 6,22 points
-after treatment 2,64 points
change 3,58 points
Statistically evaluated with test : t-test
Interval reliability for mean values /Confidence interval/
Value of VAS schould be in interval reliability for mean values
(3,56; 4,35) in 95% probability
Results
Employment after tretment:
1.employed 40 patients / 80 % /
2.no employed 10 patients / 20 % / 5 / 10%/ pat pensioned
5 / 10%/ pat disabled
Complications
-no early or late neurological complications
-no infections
-pain in root distribution by injection of mixtrure O2O3
-vegetative symtoms / vertigo,dizzines,nausea,vomitting / -5 / 10% / of patients
Conclusion
Results :
1.VAS - change 3,58 / interval reliability / 3,56 – 4,35 / statist.signif
2.modified McNab Sc. - excellent / good results 82,0 %
This study confirm original results of italian ozonotherapists and their
recommendations that oxygen-ozone therapy schould be the first option
to treat cervical disk herniation that has failed to respond to conservative
management, before recourse to surgery or when surgery is not possible.