Cranial Ppt

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    1. Cranial nerves are parts of the PNS.

    2. They are attached to the part of the CNS called the

    brain stem (midbrain, pons and medulla).

    3. Exceptions are I and II which connect directly to

    higher levels of the brain.

    4. Innervate:

    Skeletal muscles

    Sensory structures

    Smooth muscles, cardiac muscles and

    secretory glands (ANS)

    CRANIAL NERVES: PRINCIPLESCRANIAL NERVES: PRINCIPLES

    OF ORGANIZATIONOF ORGANIZATION

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    BRAIBRAI

    NN

    SS

    PP

    II

    NN

    AA

    LL

    CC

    OO

    RR

    DD

    SPINALSPINALNERVES,NERVES,Plexuses &Plexuses &

    GangliaGanglia

    CRANIALCRANIAL

    NERVES,NERVES,Plexuses &Plexuses &

    GangliaGanglia

    PERIPHERALPERIPHERALNERVOUSNERVOUS

    SYSTEMSYSTEM (PNS)(PNS)

    CENTRAL NERVOUSCENTRAL NERVOUSSYSTEM (CNS)SYSTEM (CNS)

    Head &Head &

    neckneckincludingincluding

    visceraviscera

    Head, neck,Head, neck,thorax,thorax,

    abdomen,abdomen,

    pelvis,pelvis,

    includingincluding

    viscera,viscera,

    and limbsand limbs

    SkeletalSkeletalmuscle,muscle,

    SensorySensorystructures,structures,

    SmoothSmoothmusclemuscle**,,

    CardiacCardiacmusclemuscle**,,

    SecretorySecretoryglandsglands**

    TARGETTARGET

    STRUCTURESSTRUCTURES

    *Innervated by the ANS*Innervated by the ANS

    OVERVIEW OF THE NERVOUS SYSTEMOVERVIEW OF THE NERVOUS SYSTEM

    REGIONSREGIONS

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    CRANIAL NERVES:CRANIAL NERVES:

    GENERAL FEATURESGENERAL FEATURES

    TWELVE PAIRS

    ATTACHED TO

    BRAIN STEM

    Brain stem:

    Midbrain,

    Pons, and

    Medulla

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    II

    IIII

    IIIIII

    IVIV

    V1V1

    VIVI

    VIIVIIVIIIVIII

    IXIX

    XXXIXI XIIXII

    V2V2V3V3

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    CRANIAL NERVES:CRANIAL NERVES:

    COMPOSITIONCOMPOSITION

    Some are motor nerves III, IV, VI, XI, XII

    Some are sensory nerves I, II, VIII

    Others are mixed nerves V, VII, IX, X

    Some contain autonomic(preganglionic III, VII, IX, X

    parasympathetic) fibers

    originating in the brain stem

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    CRANIAL NERVES:CRANIAL NERVES:

    NUCLEINUCLEI

    MotorNucleusMotor

    Nucleus SkeletalMuscle

    SkeletalMuscle

    ParasympatheticNucleus

    ParasympatheticNucleus

    ParasympatheticGanglion

    ParasympatheticGanglion

    SmoothMuscleCardiacMuscleGlands

    SmoothMuscleCardiacMuscleGlands

    SensoryGanglionSensoryGanglion

    SkinMucosaSkinMucosa

    Sensory

    Nucleus

    Sensory

    Nucleus

    MIDBRAINMIDBRAIN

    PONS

    MEDULLAOBLONGATAMEDULLAOBLONGATA

    BRAIN STEM

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    AUTONOMIC NERVOUS SYSTEM

    Innervates structures that arenot under voluntary control

    Target structures are: smooth

    muscles, cardiac musclesand secretory glands

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    AUTONOMIC NERVOUS SYSTE

    Sympathetic Nervous System (SNS)

    = ThoracolumbarThoracolumbaroutflow

    cell bodies of origin in T1-L2 cord segments

    Parasympathetic nervous System (PSNS)

    = CraniosacralCraniosacraloutflow

    cell bodies of origin in brain stem and S2-S4 cord

    segments

    Both SNS andPSNS have CNS andPNS

    components

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    < < TARGETS

    Two Neurons in series involved

    in ANS innervations

    Pre-ganglionic Ganglion Post-ganglionic

    CNS:T1-L2 cord,Brain

    stem, S 2-4 cord

    PNS:

    Headandneck,

    thorax,abdomen,

    pelvis

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    V: TRIGEMINALV: TRIGEMINAL

    Mixed nerve with both sensory and motormotor

    functions

    Has a motor root and a sensory root

    Because it has a sensory component, it

    has a sensory ganglion, akin to the spinal

    ganglion

    Does NOT contain preganglionicparasympathetic fibers as it leaves the brainstem

    SS MM

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    TRIGEMINALTRIGEMINALTRIGEMINALTRIGEMINAL

    V1 (OPHTHALMIC): SENSORY

    V2 (MAXILLARY): SENSORY

    V3 (MANDIBULAR): SENSORY and MOTORMOTOR

    Three branches:

    SS MM

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    EXIT THROUGH FORAMINA AT THE BASE OF THE SKULL

    CRANIAL NERVES:CRANIAL NERVES:

    GENERAL FEATURESGENERAL FEATURES

    IIII

    IIIIII

    IVIVV1V1VIVI

    VIIVII

    VIIIVIIIIXIXXX

    II

    V2V2

    V3V3

    XIIXII

    XIXI

    XIXI

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    TRIGEMINAL:

    COURSE AND FEATURES

    TRIGEMINAL:

    COURSE AND FEATURES

    V1 : Superior orbital fissure OrbitSupraorbital notch

    and foramen

    V2

    : Foramen rotundum Pterygopalatine fossa

    Inferior orbital fissure

    Infraorbital foramen

    V3: Foramen ovale Infratemporal fossa

    Mandibular canalMental foramen

    Terminal branches in the face become cutaneous nerves in the head

    including the face.

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    Preganglionic fibers for these ganglia come from other cranial

    nerves and only the postganglionic fibers are conveyed by v to

    the target structures. Trigeminal has no preganglionic

    parasympathetic components arising from the brain stem.

    Preganglionic fibers for these ganglia come from other cranial

    nerves and only the postganglionic fibers are conveyed by v to

    the target structures. Trigeminal has no preganglionic

    parasympathetic components arising from the brain stem.

    V TRIGEMINAL:V TRIGEMINAL:

    GIVES ATTACHMENT TO 4 PARASYMPATHETIC GANGLIA:GIVES ATTACHMENT TO 4 PARASYMPATHETIC GANGLIA:

    CILIARY GANGLION, ATTACHED TO V1

    PTERYGOPALATINE GANGLION, ATTACHED TO V2

    SUBMANDIBULAR GANGLION, ATTACHED TO V3

    OTIC GANGLION ATTACHED TO V3

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    MAJOR FUNCTIONS: MOTOR: V3 MUSCLES OF MASTICATION*MAJOR FUNCTIONS: MOTOR: V3 MUSCLES OF MASTICATION*

    Not shown:

    Medial & lateral

    Pterygoids

    Moves jaw

    during

    chewing/

    Mastication;under

    voluntary and

    reflex

    conditions

    Moves jaw

    during

    chewing/

    Mastication;under

    voluntary and

    reflex

    conditions

    * 4 others: Mylohyoid, ant. belly of Digastric, Tensor tympani, Tensor palati

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    SENSORYDISTRIBUTIONOF V V1

    V2

    V3

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    V TRIGEMINAL:V TRIGEMINAL:

    Conveys sensations (touch, pain, pressure etc.)

    from skin of the head (face and scalp) and

    mucosa of cavities in the head

    Responsible for consciously perceived pain

    emanating from the head: toothache, headache

    and sinus pain

    SENSORY FUNCTIONS

    Provides sensory input for for 2 reflexes oftentested during a neurologic examination:

    Corneal reflex & Jaw jerk

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    Does not contain preganglionicparasympathetic axons.

    Gives attachment to 3 parasympathetic

    ganglia.

    Helps distribute postganglionicparasympathetic fibers to lacrimal and two

    salivary glands.

    V TRIGEMINAL

    Parasympathetic Functions

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    V TRIGEMINAL:V TRIGEMINAL:

    HAVE THE PATIENT RECOGNIZE TOUCH AND PAIN

    FROM THE SKIN TERRITORIES SUPPLIED BY EACH

    DIVISION.

    COMPARE THE TWO SIDES FOR EQUAL/UNEQUAL

    RESPONSES

    NEUROOGICAL EXAM-SENSORY

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    Cranial Nerve Video # 5

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    V TRIGEMINAL:V TRIGEMINAL:

    THE PATIENT LOOKS TO ONE SIDE

    THE OPPOSITE CORNEA IS GENTLYSTIMULATED BY A WISP OF COTTON.

    THE NORMAL RESPONSE IS A

    BILATERAL CLOSURE OF THE EYES.

    V1 IS THE AFFERENT LIMB OF THEREFLEX AND THE EFFERENT LIMB IS VII.

    CORNEAL REFLEXCORNEAL REFLEX

    NEUROOGICAL EXAM-SENSORY

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    Cranial Nerve Video #6

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    V TRIGEMINAL:V TRIGEMINAL:

    Have the patient clench her teeth and

    Palpate the contraction of the masseter

    And temporalis muscles.

    Have the patient move mandible, look for normal

    movements without any deviation to either side

    NEUROOGICAL EXAM-MOTOR

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    V TRIGEMINAL:V TRIGEMINAL:

    JAW JERKJAW JERK

    Keep the jaw relaxed and the mouth slightly open

    Tap the chin to stretch the temporalis and masseter

    Jaw closure in response

    Normally weak or absent, exaggerated in some

    motor neuron diseases

    NEUROOGICAL EXAM-MOTOR

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    Cranial Nerve Video # 7

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    V TRIGEMINAL:

    DYSFUNCTIONSV TRIGEMINAL:

    DYSFUNCTIONS

    1. Loss of sensations in areas innervated.

    2. Loss of corneal reflex when affected eye

    is stimulated. Stimulation of the intact eye will result ina bilateral normal response.

    3. Paralysis of muscles of mastication,

    resulting in difficulty in chewing, and aflattening of the side of the face

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    RelatedArticles, Links

    Neurol Clin.2004 Feb;22(1):185-206.

    Trigeminal neuralgia andglossopharyngealneuralgia.

    Rozen TD.

    Michigan Head-Painand Neurological Institute, 3120Professional Drive,AnnArbor,

    MI 48104, [email protected]

    Trigeminal neuralgia andglossopharyngealneuralgiaare

    extremelypainful conditionsthattypicallyafflictanolder

    population. Distinct clinical characteristicsguidethediagnosis

    oftheseuniquesyndromes. Treatmentinvolvesmedication

    firstandthensurgicalproceduresifapatientisrefractoryto

    medicinaltherapy.Antiepileptic medicationsarethemost

    effectiveagents forthesedisorders.

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    V TRIGEMINAL:V TRIGEMINAL:

    THE MORE COMMONLY MANIFESTED CONDITIONS ARE:

    TRIGEMINAL NEURALGIA TRIGEMINAL NEURALGIA

    HERPES ZOSTERAFFECTING TRIGEMINAL

    GANGLION

    HERPES ZOSTERAFFECTING TRIGEMINAL

    GANGLION

    DYSFUNCTIONS