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cranBarriEr®The natural way to help maintain a healthy urinary tract.*

The Need

Women are naturally in need of urinary tract protection.

CompeTiTive SoluTioNS

Other supplements like CranActin® contain less cranberry extract per serving, while cranberry juice is loaded with carbs and calories.

The melaleuCa SoluTioN

A serving of CranBarrier delivers the optimal therapeutic dose of 1,000 mg of cranberry phytonutrients without all the sugar of cranberry juice to boost urinary tract health—plus a proprietary blend of blueberry and uva ursi (bearberry) extracts for additional urinary tract protection.*

The melaleuCa value

CranBarrier offers three-in-one urinary tract protection for just $13.44pc for a 30-day supply—without the cost, sugars, and carbs of cranberry juice.*

The urinary tract is made up of the kidneys, which filter waste from the blood; the ureters, which carry waste to the bladder; the urethra, which carries waste out of the body; and several muscles that allow you to hold and control urinary flow. Your kidneys work constantly, collecting excess water and waste from your blood, which is then stored in the bladder. Once your bladder is full, you feel the urge to urinate. Muscles surrounding the bladder contract while muscles holding back waste relax. The urine then passes from the body through the urethra. For generations, women have been told by their mothers to drink cranberry juice to promote urinary tract health. Once thought to be an old wives tale, there is now solid scientific evidence supporting the fact that supplementing your daily diet with cranberries can help promote a healthy urinary tract.

Cranberries: A History of Enhancing Urinary Tract HealthEuropean settlers in North America first called the fruit the “crane berry” because the vine blossoms resembled the bill, head, and neck of a crane. Over time, the name evolved into the modern “cranberry.” Common all over North America, cranberries have been found to contain a number of healthful key nutrients, including:

• anthocyanins—which are responsible for giving the cranberry its deep red color• proanthocyanins—an antioxidant and (according to some research) the effective

compound that helps urinary tract health• quercetin—a beneficial flavonoid that aids in urinary tract health

SuggeSTed uSe:Take two CranBarrier chewables daily. Chewables can be taken either with meals or on an empty stomach.

Consult your physician, health care practitioner, and/or pharmacist regarding any health problem and before using any supplements or before making changes in prescribed medications. The information presented herein is in no way intended as a substitute for medical counseling. Always read and follow label directions and warnings.

Supplement FactsServing Size 2 Tablets Servings Per Container 30

Calories

* Daily Value not established.

Ingredients: Xylitol, Molasses, Creamer, Honey, Natural Flavors, Silicon Dioxide, Magnesium Stearate (vegetable-derived), Stearic Acid (vegetable-derived).

10

5 mg

4g

2g

1000 mg

1740 mg

<1%

<1%

*

*

Amount Per Serving

% Daily Value

Cranberry Concentrate

(Vaccinium macrocarpon)

Proprietary Blend

Sodium

Total Carbohydrate

Sugar

Fructose, Blueberry (Vaccinium corymbosum and/or Vaccinium angustifolium), Bearberry (Arctostaphylos uva-ursi), Citric Acid, Glycyrrhiza Extract

* These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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A number of studies have shown the benefits of cranberries. In 1994, a groundbreaking study was published in the Journal of the American Medical Association (JAMA) which showed that the phytochemicals in cranberries are beneficial for the urinary tract.

1 A study published in the British Medical Journal confirmed the JAMA

research.2

Two more studies—one published in the Canadian Journal of Urology in 2002, the second published in 2003 in the American Journal of Clinical Nutrition demonstrated that the frequent consumption of fresh cranberry juice was associated with maintaining urinary tract health.

3,4

In addition to enhanced urinary tract health, cranberries are also beneficial to the body in other ways. (See sidebar.) Research indicates that the amount of cranberry extract required to promote urinary tract health and receive other benefits is 1,000 milligrams a day—about the same amount found in 10 ounces of pure, undiluted cranberry juice. Because many cranberry juice drinks are diluted with other juices and water to make them less bitter, it can take as much as 32 ounces of cranberry juice drink every day to get the recommended dose of cranberry needed. And because of its bitter taste, few people actually want to drink that much cranberry juice. What’s worse, cranberry juice is very high in sugar. Ten ounces of cranberry juice contains 46 grams of sugar. And juice mixes can add even more! There are cranberry supplements on the market that offer a low-sugar solution, but they are typically much more expensive than juice and fail to provide the research-recommended dose of 1,000 milligrams per day. (See comparisons in sidebar.) CranBarrier is an affordable, convenient way to get the research-recommended dose of cranberry—without the high daily dose of sugar. CranBarrier is made with the full 1,000 milligram dose that researchers have recommended as effective in urinary tract health. But CranBarrier doesn’t stop there.

CranBarrier’s Proprietary Blend of Blueberries and Uva Ursi (Bearberries)Research has shown that blueberry extracts have a beneficial effect similar to that of cranberries. A study published in the New England Journal of Medicine in 1991 reported that scientists had tested seven different fruit extracts and found that cranberry and blueberry effectively promoted urinary tract health.

9 A 5-year study published in 1998 in the New

England Journal of Medicine found that extracts from blueberries containing phytochemicals helped effectively support urinary tract health. CranBarrier also contains uva ursi, an herbal extract from bearberry which has a long history of use for urinary tract health dating back to the 1600s. Its effectiveness has recently been backed up by a scientific study in which the beneficial effect of uva ursi was evaluated in a double blind study of 57 women.

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The 3-in-1 formula of CranBarrier—which no other cranberry supplement contains—makes it the best natural supplement for urinary tract health of its kind.*

addiTioNal healTh BeNefiTS of CraNBerry*While numerous cultures have recognized the urinary health benefits of cranberries, recent research has also found that cranberries:• promote healthy teeth and gums

5*

• promote stomach health6*

• promote cognitive thinking by protecting the brain cells from free-radical damage

7*

• protect heart health by inhibiting LDL (“bad”) cholesterol oxidation

8*

addiTioNal ThiNgS you CaN do To maiNTaiN uriNary TraCT healThExperts agree that there are a number of diet and lifestyle changes, which, when incorporated into a daily routine, can help maintain urinary tract health.• Drink plenty of fluids• Urinate when you feel the urge; don’t

postpone visiting the bathroom• Wipe from the front to the back to

prevent bacteria from the intestines from getting into the urinary tract

• Cleanse the genital area daily and before sexual intercourse

• Urinate after sexual intercourse

* These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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Maintaining a Healthy Urinary Tract—NaturallyWhen it comes to maintaining a healthy urinary tract, natural solutions like CranBarrier work. With the therapeutic dose of 1,000 mg of cranberry extract—plus a proprietary blend of blueberry and uva ursi—CranBarrier is the best choice for urinary tract health.*

CraNBarrier iS a BeTTer ChoiCe aNd a BeTTer value

SupporTiNg reSearCh

1. J Avron, M Monane, et al., “Reduction of Bacteriuria and Pyruia After Ingestion of Cranberry Juice,” Journal of the American Medical Association, Vol. 271, No. 10, March 9, 1994, p. 751–754.

2. T Kontiokari et al., “Randomized trial of cranberry-lingonberry juice and Lactobacillus CG drink for the prevention of urinary tract infections in women,” British Medical Journal, Vol. 322, June 30, 2001, p. 1571.

3. L Stothers, “A randomized trial to evaluate the effectiveness and cost effectiveness of naturopathic cranberry products as prophylaxis against urinary tract infection in women,” Canadian Journal of Urology, Vol. 9, No. 3, June 2002, p.1558–1562.

4. T Kontiokari et al., “Dietary factors protecting women from urinary tract infection,” American Journal of Clinical Nutrition, Vol. 77, No. 3, March 2003, p. 600–604.

5. Weiss E et al., “Inhibitory effect of high-molecular-weight constituent of cranberry on adhesion of oral bacteria,” Critical Reviews in Food Science & Nutrition, Vol. 42 (supplement), 2002, p. 285–292.

6. O Burger et al., “Inhibition of Helicobacter pylori adhesion to human gastric mucus by a high-molecular-weight consistent of cranberry juice, “ Critical Reviews in Food Science & Nutrition, Vol. 42 (supplement), 2002, .

7. JA Joseph et al., The Color Code—A Revolutionary Eating Plan for Optimal Health, 1st ed., 2002.

8. CG Krueger et al., “Potential of cranberry flavonoids in the prevention of copper-induced LDL oxidation,” Polyphenols Communication, Freising-Weihenstephan (Germany), Vol. 2, 2000, p. 447–448.

9. I Ofek et al., “Anti-escherichia activity of cranberry and blueberry juices,” New England Journal of Medicine, Vol. 324, No. 22, 1991, p. 1599.

10. B Larsson, A Jonasson, S Fianu, “Prophylactic effect of UVA-E in women with recurrent cystitis: a preliminary report,” Current Therapeutic Research, Vol. 53, No. 4, April 1993, p. 441–443.

Product Monthly cost†

CranActin® $18.18

Ocean Spray® $34.99 Cranberry Juice

CranBarrier $13.44

† Preferred Customer price. All prices are equivalized to reflect the recommended 1,000 mg dose over 30 days. †Pricing from VitaminShoppe.com, May, 2010. Other competitor product prices from National Retail Grocers, May, 2010. Nutritional information based on 32 oz. of Ocean Spray Cranberry Juice. Product names are registered trademarks of their respective companies.

caloriEs carBs sugars

Ocean Spray® Premium 175 42.5g 42.5g Cranberry Blend

CranBarrier 10 3g 2g

* These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.